Year |
Citation |
Score |
2011 |
Eberhart AJ, Imbriglio JE, Procter DJ. Nucleophilic ortho allylation of aryl and heteroaryl sulfoxides Organic Letters. 13: 5882-5885. PMID 21999481 DOI: 10.1021/Ol2025197 |
0.352 |
|
2009 |
Mangion I, Strotman N, Drahl M, Imbriglio J, Guidry E. Dynamic kinetic asymmetric allylation of hydrazines and hydroxylamines. Organic Letters. 11: 3258-60. PMID 19588911 DOI: 10.1055/S-0029-1218085 |
0.386 |
|
2003 |
Imbriglio JE, Vasbinder MM, Miller SJ. Dual catalyst control in the amino acid-peptide-catalyzed enantioselective Baylis-Hillman reaction. Organic Letters. 5: 3741-3. PMID 14507219 DOI: 10.1021/Ol035466B |
0.315 |
|
2001 |
Imbriglio JE, Rainier JD. [2+2+1] Cycloadditions of ynol ethers. The synthesis of iron complexes of 3-alkoxycyclopentadienones Tetrahedron Letters. 42: 6987-6990. DOI: 10.1016/S0040-4039(01)01473-3 |
0.563 |
|
2000 |
Rainier JD, Imbriglio JE. The synthesis and chemoselective reactivity of 3-aminocyclopentadienones The Journal of Organic Chemistry. 65: 7272-6. PMID 11076583 DOI: 10.1021/Jo001044T |
0.573 |
|
1999 |
Rainier JD, Imbriglio JE. Synthesis and Chemoselective Reactivity of 3-aminocyclopentadienones Organic Letters. 1: 2037-2039. DOI: 10.1021/Ol9912128 |
0.524 |
|
Low-probability matches (unlikely to be authored by this person) |
2005 |
Mennen SM, Blank JT, Tran-Dubé MB, Imbriglio JE, Miller SJ. A peptide-catalyzed asymmetric Stetter reaction. Chemical Communications (Cambridge, England). 195-7. PMID 15724183 DOI: 10.1039/B414574G |
0.263 |
|
2006 |
Vasbinder MM, Imbriglio JE, Miller SJ. Amino acid-peptide-catalyzed enantioselective Morita-Baylis-Hillman reactions Tetrahedron. 62: 11450-11459. DOI: 10.1016/J.Tet.2006.05.005 |
0.25 |
|
2008 |
Imbriglio JE, DiRocco D, Raghavan S, Ball RG, Tsou N, Mosley RT, Tata JR, Colletti SL. The synthesis and conformational analysis of amino acid-tetrahydroanthranilic acid hybrids Tetrahedron Letters. 49: 4897-4900. DOI: 10.1016/j.tetlet.2008.05.148 |
0.216 |
|
2018 |
McLaren DG, Han S, Murphy BA, Wilsie L, Stout SJ, Zhou H, Roddy TP, Gorski JN, Metzger DE, Shin MK, Reilly DF, Zhou HH, Tadin-Strapps M, Bartz SR, Cumiskey AM, ... ... Imbriglio JE, et al. DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates. Cell Metabolism. PMID 29706567 DOI: 10.1016/J.Cmet.2018.04.004 |
0.141 |
|
1996 |
Imbriglio J, Patel P, Rotello VM. Model systems for cofactor activity. Biomimetic reduction of vitamin K by 1,3-propanedithiol Heteroatom Chemistry. 7: 293-294. |
0.125 |
|
2022 |
Dixon T, MacPherson D, Mostofian B, Dauzhenka T, Lotz S, McGee D, Shechter S, Shrestha UR, Wiewiora R, McDargh ZA, Pei F, Pal R, Ribeiro JV, Wilkerson T, Sachdeva V, ... ... Imbriglio J, et al. Predicting the structural basis of targeted protein degradation by integrating molecular dynamics simulations with structural mass spectrometry. Nature Communications. 13: 5884. PMID 36202813 DOI: 10.1038/s41467-022-33575-4 |
0.119 |
|
2020 |
Daurio NA, Zhou H, Chen Y, Sheth PR, Imbriglio JE, McLaren DG, Tawa P, Rachdaoui N, Previs MJ, Kasumov T, O'Neil J, Previs SF. Examining targeted protein degradation from physiological and analytical perspectives: Enabling translation between cells and subjects. Acs Chemical Biology. PMID 32930572 DOI: 10.1021/acschembio.0c00380 |
0.097 |
|
2009 |
Imbriglio JE, Chang S, Liang R, Raghavan S, Schmidt D, Smenton A, Tria S, Schrader TO, Jung JK, Esser C, Taggart AK, Cheng K, Carballo-Jane E, Gerard Waters M, Tata JR, et al. GPR109a agonists. Part 1: 5-Alkyl and 5-aryl-pyrazole-tetrazoles as agonists of the human orphan G-protein coupled receptor GPR109a. Bioorganic & Medicinal Chemistry Letters. 19: 2121-4. PMID 19307116 DOI: 10.1016/J.Bmcl.2009.03.014 |
0.086 |
|
2017 |
Chitraju C, Mejhert N, Haas JT, Diaz-Ramirez LG, Grueter CA, Imbriglio JE, Pinto S, Koliwad SK, Walther TC, Farese RV. Triglyceride Synthesis by DGAT1 Protects Adipocytes from Lipid-Induced ER Stress during Lipolysis. Cell Metabolism. 26: 407-418.e3. PMID 28768178 DOI: 10.1016/J.Cmet.2017.07.012 |
0.08 |
|
2011 |
McLaren DG, He T, Wang SP, Mendoza V, Rosa R, Gagen K, Bhat G, Herath K, Miller PL, Stribling S, Taggart A, Imbriglio J, Liu J, Chen D, Pinto S, et al. The use of stable-isotopically labeled oleic acid to interrogate lipid assembly in vivo: assessing pharmacological effects in preclinical species. Journal of Lipid Research. 52: 1150-61. PMID 21415123 DOI: 10.1194/Jlr.M011049 |
0.08 |
|
2019 |
Petrilli WL, Adam GC, Erdmann RS, Abeywickrema P, Agnani V, Ai X, Baysarowich J, Byrne N, Caldwell JP, Chang W, DiNunzio E, Feng Z, Ford R, Ha S, Huang Y, ... ... Imbriglio JE, et al. From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9. Cell Chemical Biology. PMID 31653597 DOI: 10.1016/J.Chembiol.2019.10.002 |
0.07 |
|
1997 |
Niemz A, Imbriglio J, Rotello VM. Model systems for flavoenzyme activity: One- and two-electron reduction of flavins in aprotic hydrophobic environments Journal of the American Chemical Society. 119: 887-892. DOI: 10.1021/Ja963704A |
0.068 |
|
2010 |
Imbriglio JE, Chang S, Liang R, Raghavan S, Schmidt D, Smenton A, Tria S, Schrader TO, Jung JK, Esser C, Holt TG, Wolff MS, Taggart AK, Cheng K, Carballo-Jane E, et al. GPR109a agonists. Part 2: pyrazole-acids as agonists of the human orphan G-protein coupled receptor GPR109a. Bioorganic & Medicinal Chemistry Letters. 20: 4472-4. PMID 20615702 DOI: 10.1016/J.Bmcl.2010.06.041 |
0.059 |
|
2021 |
Petrilli WL, Adam GC, Erdmann RS, Abeywickrema P, Agnani V, Ai X, Baysarowich J, Byrne N, Caldwell JP, Chang W, DiNunzio E, Feng Z, Ford R, Ha S, Huang Y, ... ... Imbriglio JE, et al. From Screening to Targeted Degradation: Strategies for the Discovery and Optimization of Small Molecule Ligands for PCSK9. Cell Chemical Biology. 28: 243. PMID 33607006 DOI: 10.1016/j.chembiol.2021.01.019 |
0.056 |
|
2011 |
Imbriglio JE, DiRocco D, Bodner R, Raghavan S, Chen W, Marley D, Esser C, Holt TG, Wolff MS, Taggart AK, Waters MG, Tata JR, Colletti SL. The discovery of high affinity agonists of GPR109a with reduced serum shift and improved ADME properties. Bioorganic & Medicinal Chemistry Letters. 21: 2721-4. PMID 21185185 DOI: 10.1016/j.bmcl.2010.11.116 |
0.055 |
|
2014 |
Blizzard TA, Chen H, Kim S, Wu J, Bodner R, Gude C, Imbriglio J, Young K, Park YW, Ogawa A, Raghoobar S, Hairston N, Painter RE, Wisniewski D, Scapin G, et al. Discovery of MK-7655, a β-lactamase inhibitor for combination with Primaxin®. Bioorganic & Medicinal Chemistry Letters. 24: 780-5. PMID 24433862 DOI: 10.1016/j.bmcl.2013.12.101 |
0.05 |
|
2015 |
Imbriglio JE, Shen DM, Liang R, Marby K, You M, Youm HW, Feng Z, London C, Xiong Y, Tata J, Verras A, Garcia-Calvo M, Song X, Addona G, McLaren DG, et al. The Discovery and Pharmacology of a Novel Class of Diacylglycerol Acyltransferase 2 (DGAT2) Inhibitors. Journal of Medicinal Chemistry. PMID 26561979 DOI: 10.1021/acs.jmedchem.5b01345 |
0.043 |
|
2017 |
Sanders JM, Beshore DC, Culberson JC, Fells JI, Imbriglio JE, Gunaydin H, Haidle AM, Labroli M, Mattioni BE, Sciammetta N, Shipe WD, Sheridan RP, Suen LM, Verras A, Walji AM, et al. Informing the selection of screening hit series with in silico absorption, distribution, metabolism, excretion, and toxicity profiles. Journal of Medicinal Chemistry. PMID 28418656 DOI: 10.1021/Acs.Jmedchem.6B01577 |
0.039 |
|
2021 |
Choy J, Kan Y, Cifelli S, Johnson J, Chen M, Shiao LL, Zhou H, Previs S, Lei Y, Johnstone R, Liaw A, Saigal A, Hu L, Ramos R, Visconti R, ... ... Imbriglio J, et al. High-Throughput Screening to Identify Small Molecules That Selectively Inhibit APOL1 Protein Level in Podocytes. Slas Discovery : Advancing Life Sciences R & D. 24725552211026245. PMID 34218698 DOI: 10.1177/24725552211026245 |
0.038 |
|
2016 |
Wickham LA, Sitko G, Stranieri-Michener M, Handt L, Basso A, Fried S, Chu L, Maderia M, Owens K, Castriota G, Chen Z, Metzger JM, Imbriglio J, Wang X, Cai TQ. Differential anti-thrombotic benefit and bleeding risk profiles of antagonists of protease-activated receptor 1 and 4 in Cynomolgus Macaques. Thrombosis Research. PMID 27318768 DOI: 10.1016/j.thromres.2016.06.007 |
0.033 |
|
2020 |
Lam PY, Kutchukian P, Anand R, Imbriglio J, Andrews C, Padilla H, Vohra A, Lane S, Parker DL, Taracido IC, Johns DG, Beerens M, MacRae CA, Caldwell J, Sorota S, et al. Cyp1 inhibition prevents doxorubicin-induced cardiomyopathy in a zebrafish heart failure model. Chembiochem : a European Journal of Chemical Biology. PMID 32003101 DOI: 10.1002/Cbic.201900741 |
0.032 |
|
2020 |
Zhang J, Muise ES, Han S, Kutchukian PS, Costet P, Zhu Y, Kan Y, Zhou H, Shah V, Huang Y, Saigal A, Akiyama TE, Shen XL, Cai TQ, Shah K, ... ... Imbriglio J, et al. Molecular Profiling Reveals a Common Metabolic Signature of Tissue Fibrosis. Cell Reports. Medicine. 1: 100056. PMID 33205063 DOI: 10.1016/j.xcrm.2020.100056 |
0.026 |
|
2015 |
Song XS, Zhang J, Chen X, Palyha O, Chung C, Sonatore LM, Wilsie L, Stout S, McLaren DG, Taggart A, Imbriglio JE, Pinto S, Garcia-Calvo M, Addona GH. Identification of DGAT2 Inhibitors Using Mass Spectrometry. Journal of Biomolecular Screening. PMID 26403520 DOI: 10.1177/1087057115607463 |
0.026 |
|
Hide low-probability matches. |