Linda P. Spear - Publications

Affiliations: 
State University of New York, Binghamton, Vestal, NY, United States 

245 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Crews FT, Robinson DL, Chandler LJ, Ehlers CL, Mulholland PJ, Pandey SC, Rodd ZA, Spear LP, Swartzwelder HS, Vetreno RP. Mechanisms of persistent neurobiological changes following adolescent alcohol exposure: NADIA Consortium findings. Alcoholism, Clinical and Experimental Research. PMID 31335972 DOI: 10.1111/acer.14154  0.84
2019 Landin JD, Palac M, Carter JM, Dzumaga Y, Santerre-Anderson JL, Fernandez GM, Savage LM, Varlinskaya EI, Spear LP, Moore SD, Swartzwelder HS, Fleming RL, Werner DF. General anesthetic exposure in adolescent rats causes persistent maladaptations in cognitive and affective behaviors and neuroplasticity. Neuropharmacology. PMID 30926450 DOI: 10.1016/j.neuropharm.2019.03.022  0.88
2018 Kim EU, Varlinskaya EI, Dannenhoffer CA, Spear LP. Adolescent intermittent ethanol exposure: Effects on pubertal development, novelty seeking, and social interaction in adulthood. Alcohol (Fayetteville, N.Y.). 75: 19-29. PMID 30326391 DOI: 10.1016/j.alcohol.2018.05.002  0.88
2018 Dannenhoffer CA, Kim EU, Saalfield J, Werner DF, Varlinskaya EI, Spear LP. Oxytocin and vasopressin modulation of social anxiety following adolescent intermittent ethanol exposure. Psychopharmacology. PMID 30141056 DOI: 10.1007/s00213-018-5003-8  0.88
2016 Doremus-Fitzwater TL, Spear LP. Reward-centricity and attenuated aversions: An adolescent phenotype emerging from studies in laboratory animals. Neuroscience and Biobehavioral Reviews. PMID 27524639 DOI: 10.1016/j.neubiorev.2016.08.015  1
2016 Spear LP, Silveri MM. INTRODUCTION: SPECIAL ISSUE ON THE ADOLESCENT BRAIN. Neuroscience and Biobehavioral Reviews. PMID 27497719 DOI: 10.1016/j.neubiorev.2016.08.004  1
2016 Varlinskaya EI, Kim EU, Spear LP. Chronic intermittent ethanol exposure during adolescence: Effects on stress-induced social alterations and social drinking in adulthood. Brain Research. PMID 27048754 DOI: 10.1016/j.brainres.2016.03.050  0.88
2016 Fernández MS, Fabio MC, Miranda-Morales RS, Virgolini MB, De Giovanni LN, Hansen C, Wille-Bille A, Nizhnikov ME, Spear LP, Pautassi RM. Age-related effects of chronic restraint stress on ethanol drinking, ethanol-induced sedation, and on basal and stress-induced anxiety response. Alcohol (Fayetteville, N.Y.). PMID 26830848 DOI: 10.1016/j.alcohol.2015.11.009  1
2016 Saalfield J, Spear L. The ontogeny of ethanol aversion Physiology and Behavior. 156: 164-170. DOI: 10.1016/j.physbeh.2016.01.011  1
2015 Shnitko TA, Spear LP, Robinson DL. Adolescent binge-like alcohol alters sensitivity to acute alcohol effects on dopamine release in the nucleus accumbens of adult rats. Psychopharmacology. PMID 26487039 DOI: 10.1007/s00213-015-4106-8  1
2015 Kim EU, Spear LP. Sex-dependent consequences of pre-pubertal gonadectomy: Social behavior, stress and ethanol responsivity. Behavioural Brain Research. 296: 260-269. PMID 26386303 DOI: 10.1016/j.bbr.2015.09.022  1
2015 Spear LP. Adolescent alcohol exposure: Are there separable vulnerable periods within adolescence? Physiology & Behavior. 148: 122-30. PMID 25624108 DOI: 10.1016/j.physbeh.2015.01.027  1
2015 Varlinskaya EI, Truxell EM, Spear LP. Ethanol intake under social circumstances or alone in sprague-dawley rats: impact of age, sex, social activity, and social anxiety-like behavior. Alcoholism, Clinical and Experimental Research. 39: 117-25. PMID 25623411 DOI: 10.1111/acer.12604  1
2015 Varlinskaya EI, Truxell EM, Spear LP. Sex differences in sensitivity to the social consequences of acute ethanol and social drinking during adolescence. Behavioural Brain Research. 282: 6-13. PMID 25557799 DOI: 10.1016/j.bbr.2014.12.054  1
2015 Usala JM, Celio MA, Lisman SA, Day AM, Spear LP. A field investigation of the effects of drinking consequences on young adults' readiness to change. Addictive Behaviors. 41: 162-8. PMID 25452061 DOI: 10.1016/j.addbeh.2014.10.016  1
2015 Varlinskaya EI, Spear LP. Social consequences of ethanol: Impact of age, stress, and prior history of ethanol exposure. Physiology & Behavior. 148: 145-50. PMID 25431835 DOI: 10.1016/j.physbeh.2014.11.062  1
2014 Shnitko TA, Kennerly LC, Spear LP, Robinson DL. Ethanol reduces evoked dopamine release and slows clearance in the rat medial prefrontal cortex. Alcoholism, Clinical and Experimental Research. 38: 2969-77. PMID 25581652 DOI: 10.1111/acer.12587  1
2014 McClory AJ, Spear LP. Effects of ethanol exposure during adolescence or in adulthood on Pavlovian conditioned approach in Sprague-Dawley rats. Alcohol (Fayetteville, N.Y.). 48: 755-63. PMID 25449366 DOI: 10.1016/j.alcohol.2014.05.006  1
2014 Vetreno RP, Broadwater M, Liu W, Spear LP, Crews FT. Adolescent, but not adult, binge ethanol exposure leads to persistent global reductions of choline acetyltransferase expressing neurons in brain. Plos One. 9: e113421. PMID 25405505 DOI: 10.1371/journal.pone.0113421  1
2014 Broadwater MA, Liu W, Crews FT, Spear LP. Persistent loss of hippocampal neurogenesis and increased cell death following adolescent, but not adult, chronic ethanol exposure. Developmental Neuroscience. 36: 297-305. PMID 24993092 DOI: 10.1159/000362874  1
2014 Varlinskaya EI, Truxell E, Spear LP. Chronic intermittent ethanol exposure during adolescence: effects on social behavior and ethanol sensitivity in adulthood. Alcohol (Fayetteville, N.Y.). 48: 433-44. PMID 24928792 DOI: 10.1016/j.alcohol.2014.01.012  1
2014 Saalfield J, Spear L. Developmental differences in the effects of alcohol and stress on heart rate variability Physiology and Behavior. 135: 72-80. PMID 24907690 DOI: 10.1016/j.physbeh.2014.05.037  1
2014 Morales M, Varlinskaya EI, Spear LP. Pre-pubertal gonadectomy and the social consequences of acute ethanol in adolescent male and female rats. Hormones and Behavior. 66: 209-19. PMID 24816080 DOI: 10.1016/j.yhbeh.2014.04.015  1
2014 Spear LP, Swartzwelder HS. Adolescent alcohol exposure and persistence of adolescent-typical phenotypes into adulthood: a mini-review. Neuroscience and Biobehavioral Reviews. 45: 1-8. PMID 24813805 DOI: 10.1016/j.neubiorev.2014.04.012  1
2014 Broadwater M, Spear LP. Consequences of adolescent or adult ethanol exposure on tone and context fear retention: effects of an acute ethanol challenge during conditioning. Alcoholism, Clinical and Experimental Research. 38: 1454-60. PMID 24588350 DOI: 10.1111/acer.12382  1
2014 Morales M, Schatz KC, Anderson RI, Spear LP, Varlinskaya EI. Conditioned taste aversion to ethanol in a social context: impact of age and sex. Behavioural Brain Research. 261: 323-7. PMID 24406726 DOI: 10.1016/j.bbr.2013.12.048  1
2014 Broadwater MA, Spear LP. Tone conditioning potentiates rather than overshadows context fear in adult animals following adolescent ethanol exposure. Developmental Psychobiology. 56: 1150-5. PMID 24339140 DOI: 10.1002/dev.21186  1
2014 Spear LP. Adolescents and alcohol: acute sensitivities, enhanced intake, and later consequences. Neurotoxicology and Teratology. 41: 51-9. PMID 24291291 DOI: 10.1016/j.ntt.2013.11.006  1
2014 Day AM, Celio MA, Lisman SA, Spear LP. Gender, history of alcohol use and number of drinks consumed predict craving among drinkers in a field setting. Addictive Behaviors. 39: 354-7. PMID 24148138 DOI: 10.1016/j.addbeh.2013.10.014  1
2014 Willey AR, Spear LP. Effects of ethanol on social approach and 50 kHz ultrasonic vocalization production in adolescent male Sprague-Dawley rats. Developmental Psychobiology. 56: 857-63. PMID 24122618 DOI: 10.1002/dev.21143  1
2014 Celio MA, Usala JM, Lisman SA, Johansen GE, Vetter-O'Hagen CS, Spear LP. Are we drunk yet? Motor versus cognitive cues of subjective intoxication. Alcoholism, Clinical and Experimental Research. 38: 538-44. PMID 24117655 DOI: 10.1111/acer.12276  1
2014 Morales M, Spear LP. The effects of an acute challenge with the NMDA receptor antagonists, MK-801, PEAQX, and ifenprodil, on social inhibition in adolescent and adult male rats. Psychopharmacology. 231: 1797-807. PMID 24043344 DOI: 10.1007/s00213-013-3278-3  1
2014 Anderson RI, Spear LP. Age differences in ethanol discrimination: acquisition and ethanol dose generalization curves following multiple training conditions in adolescent and adult rats. Alcoholism, Clinical and Experimental Research. 38: 186-94. PMID 23952249 DOI: 10.1111/acer.12255  1
2014 Morales M, Anderson RI, Spear LP, Varlinskaya EI. Effects of the kappa opioid receptor antagonist, nor-binaltorphimine, on ethanol intake: impact of age and sex. Developmental Psychobiology. 56: 700-12. PMID 23754134 DOI: 10.1002/dev.21137  1
2014 Anderson RI, Morales M, Spear LP, Varlinskaya EI. Pharmacological activation of kappa opioid receptors: aversive effects in adolescent and adult male rats. Psychopharmacology. 231: 1687-93. PMID 23604334 DOI: 10.1007/s00213-013-3095-8  1
2014 Spear LP. The use of psychopharmacological procedures to analyse the ontogeny of learn i ng and retention: Issues andconcerns Ontogeny of Learning and Memory. 135-156.  1
2013 Spear LP. ADOLESCENTS AND ALCOHOL. Current Directions in Psychological Science. 22: 152-157. PMID 25309054 DOI: 10.1177/0963721412472192  1
2013 Varlinskaya EI, Truxell EM, Spear LP. Repeated restraint stress alters sensitivity to the social consequences of ethanol differentially in early and late adolescent rats. Pharmacology, Biochemistry, and Behavior. 113: 38-45. PMID 24161685 DOI: 10.1016/j.pbb.2013.10.016  1
2013 Anderson RI, Bush PC, Spear LP. Environmental manipulations alter age differences in attribution of incentive salience to reward-paired cues. Behavioural Brain Research. 257: 83-9. PMID 24050888 DOI: 10.1016/j.bbr.2013.09.021  1
2013 Varlinskaya EI, Vetter-O'Hagen CS, Spear LP. Puberty and gonadal hormones: role in adolescent-typical behavioral alterations. Hormones and Behavior. 64: 343-9. PMID 23998677 DOI: 10.1016/j.yhbeh.2012.11.012  1
2013 Broadwater M, Spear LP. Consequences of ethanol exposure on cued and contextual fear conditioning and extinction differ depending on timing of exposure during adolescence or adulthood. Behavioural Brain Research. 256: 10-9. PMID 23938333 DOI: 10.1016/j.bbr.2013.08.013  1
2013 Broadwater M, Spear LP. Age differences in fear retention and extinction in male Sprague-Dawley rats: effects of ethanol challenge during conditioning. Behavioural Brain Research. 252: 377-87. PMID 23810415 DOI: 10.1016/j.bbr.2013.06.029  1
2013 Acevedo MB, Pautassi RM, Spear NE, Spear LP. Age-dependent effects of stress on ethanol-induced motor activity in rats. Psychopharmacology. 230: 389-98. PMID 23775530 DOI: 10.1007/s00213-013-3163-0  1
2013 Day AM, Celio MA, Lisman SA, Johansen GE, Spear LP. Acute and chronic effects of alcohol on trail making test performance among underage drinkers in a field setting. Journal of Studies On Alcohol and Drugs. 74: 635-41. PMID 23739029  1
2013 Morales M, Varlinskaya EI, Spear LP. Anxiolytic effects of the GABA(A) receptor partial agonist, L-838,417: impact of age, test context familiarity, and stress. Pharmacology, Biochemistry, and Behavior. 109: 31-7. PMID 23664899 DOI: 10.1016/j.pbb.2013.05.004  1
2013 Morales M, Varlinskaya EI, Spear LP. Low doses of the NMDA receptor antagonists, MK-801, PEAQX, and ifenprodil, induces social facilitation in adolescent male rats. Behavioural Brain Research. 250: 18-22. PMID 23651880 DOI: 10.1016/j.bbr.2013.04.050  1
2013 Willey AR, Spear LP. The effects of pre-test social deprivation on a natural reward incentive test and concomitant 50 kHz ultrasonic vocalization production in adolescent and adult male Sprague-Dawley rats. Behavioural Brain Research. 245: 107-12. PMID 23454851 DOI: 10.1016/j.bbr.2013.02.020  1
2013 Willey AR, Spear LP. Effects of acute ethanol administration and chronic stress exposure on social investigation and 50kHz ultrasonic vocalizations in adolescent and adult male Sprague-Dawley rats. Pharmacology, Biochemistry, and Behavior. 105: 17-25. PMID 23360955 DOI: 10.1016/j.pbb.2013.01.012  1
2013 Spear LP. Adolescent neurodevelopment. The Journal of Adolescent Health : Official Publication of the Society For Adolescent Medicine. 52: S7-13. PMID 23332574 DOI: 10.1016/j.jadohealth.2012.05.006  1
2013 Broadwater M, Varlinskaya EI, Spear LP. Effects of voluntary access to sweetened ethanol during adolescence on intake in adulthood. Alcoholism, Clinical and Experimental Research. 37: 1048-55. PMID 23278242 DOI: 10.1111/acer.12049  1
2013 Anderson RI, Agoglia AE, Morales M, Varlinskaya EI, Spear LP. Stress, κ manipulations, and aversive effects of ethanol in adolescent and adult male rats. Neuroscience. 249: 214-22. PMID 23276674 DOI: 10.1016/j.neuroscience.2012.12.028  1
2013 Morales M, Spear LP. Differences in sensitivity to ethanol-induced conditioned taste aversions emerge after pre- or post-pubertal gonadectomy in male and female rats. Behavioural Brain Research. 240: 69-75. PMID 23195111 DOI: 10.1016/j.bbr.2012.11.020  1
2013 Varlinskaya EI, Vogt BA, Spear LP. Social context induces two unique patterns of c-Fos expression in adolescent and adult rats. Developmental Psychobiology. 55: 684-97. PMID 22851043 DOI: 10.1002/dev.21064  1
2013 Spear LP. The Role of Brain Development in Drug Effect and Drug Response Biological Research On Addiction. 271-280. DOI: 10.1016/B978-0-12-398335-0.00028-5  1
2012 Doremus-Fitzwater TL, Barreto M, Spear LP. Age-related differences in impulsivity among adolescent and adult Sprague-Dawley rats. Behavioral Neuroscience. 126: 735-41. PMID 22889309 DOI: 10.1037/a0029697  1
2012 Morales M, Varlinskaya EI, Spear LP. Evidence for conditioned place preference to a moderate dose of ethanol in adult male Sprague-Dawley rats. Alcohol (Fayetteville, N.Y.). 46: 643-8. PMID 22784435 DOI: 10.1016/j.alcohol.2012.06.001  1
2012 Vetter-O'Hagen CS, Spear LP. The effects of gonadectomy on sex- and age-typical responses to novelty and ethanol-induced social inhibition in adult male and female Sprague-Dawley rats. Behavioural Brain Research. 227: 224-32. PMID 22036699 DOI: 10.1016/j.bbr.2011.10.023  1
2012 Varlinskaya EI, Spear LP. Increases in anxiety-like behavior induced by acute stress are reversed by ethanol in adolescent but not adult rats. Pharmacology, Biochemistry, and Behavior. 100: 440-50. PMID 22024161 DOI: 10.1016/j.pbb.2011.10.010  1
2012 Willey AR, Spear LP. Development of anticipatory 50 kHz USV production to a social stimuli in adolescent and adult male Sprague-Dawley rats. Behavioural Brain Research. 226: 613-8. PMID 22004980 DOI: 10.1016/j.bbr.2011.10.001  1
2012 Vetter-O'Hagen CS, Spear LP. Hormonal and physical markers of puberty and their relationship to adolescent-typical novelty-directed behavior. Developmental Psychobiology. 54: 523-35. PMID 21953609 DOI: 10.1002/dev.20610  1
2012 Willey AR, Anderson RI, Morales M, Ramirez RL, Spear LP. Effects of ethanol administration on corticosterone levels in adolescent and adult rats. Alcohol (Fayetteville, N.Y.). 46: 29-36. PMID 21917408 DOI: 10.1016/j.alcohol.2011.08.005  1
2011 Spear LP. Adolescent neurobehavioral characteristics, alcohol sensitivities, and intake: Setting the stage for alcohol use disorders? Child Development Perspectives. 5: 231-238. PMID 22328900 DOI: 10.1111/j.1750-8606.2011.00182.x  1
2011 Spear LP. Rewards, aversions and affect in adolescence: emerging convergences across laboratory animal and human data. Developmental Cognitive Neuroscience. 1: 392-400. PMID 21918675 DOI: 10.1016/j.dcn.2011.08.001  1
2011 Broadwater M, Varlinskaya EI, Spear LP. Different chronic ethanol exposure regimens in adolescent and adult male rats: effects on tolerance to ethanol-induced motor impairment. Behavioural Brain Research. 225: 358-62. PMID 21782854 DOI: 10.1016/j.bbr.2011.07.013  1
2011 Vetter-O'Hagen CS, Sanders KW, Spear LP. Evidence for suppressant effects of testosterone on sex-typical ethanol intake in male Sprague-Dawley rats. Behavioural Brain Research. 224: 403-7. PMID 21726585 DOI: 10.1016/j.bbr.2011.06.020  1
2011 Celio MA, Vetter-O'Hagen CS, Lisman SA, Johansen GE, Spear LP. Integrating field methodology and web-based data collection to assess the reliability of the Alcohol Use Disorders Identification Test (AUDIT). Drug and Alcohol Dependence. 119: 142-4. PMID 21724340 DOI: 10.1016/j.drugalcdep.2011.05.035  1
2011 Vetter-O'Hagen CS, Spear LP. The effects of gonadectomy on age- and sex-typical patterns of ethanol consumption in Sprague-Dawley rats. Alcoholism, Clinical and Experimental Research. 35: 2039-49. PMID 21651581 DOI: 10.1111/j.1530-0277.2011.01555.x  1
2011 Morales M, Varlinskaya EI, Spear LP. Age differences in the expression of acute and chronic tolerance to ethanol in male and female rats. Alcoholism, Clinical and Experimental Research. 35: 1614-24. PMID 21599716 DOI: 10.1111/j.1530-0277.2011.01508.x  1
2011 Doremus-Fitzwater TL, Spear LP. Amphetamine-induced incentive sensitization of sign-tracking behavior in adolescent and adult female rats. Behavioral Neuroscience. 125: 661-7. PMID 21534648 DOI: 10.1037/a0023763  1
2011 Broadwater M, Varlinskaya EI, Spear LP. Chronic intermittent ethanol exposure in early adolescent and adult male rats: effects on tolerance, social behavior, and ethanol intake. Alcoholism, Clinical and Experimental Research. 35: 1392-403. PMID 21352250 DOI: 10.1111/j.1530-0277.2011.01474.x  1
2011 Ramirez RL, Varlinskaya EI, Spear LP. Effect of the selective NMDA NR2B antagonist, ifenprodil, on acute tolerance to ethanol-induced motor impairment in adolescent and adult rats. Alcoholism, Clinical and Experimental Research. 35: 1149-59. PMID 21352242 DOI: 10.1111/j.1530-0277.2011.01448.x  1
2011 Anderson RI, Spear LP. Autoshaping in adolescence enhances sign-tracking behavior in adulthood: impact on ethanol consumption. Pharmacology, Biochemistry, and Behavior. 98: 250-60. PMID 21238477 DOI: 10.1016/j.pbb.2011.01.004  1
2011 Pautassi RM, Myers M, Spear LP, Molina JC, Spear NE. Ethanol induces second-order aversive conditioning in adolescent and adult rats. Alcohol (Fayetteville, N.Y.). 45: 45-55. PMID 21187242 DOI: 10.1016/j.alcohol.2010.10.004  1
2011 Robinson DL, Zitzman DL, Smith KJ, Spear LP. Fast dopamine release events in the nucleus accumbens of early adolescent rats. Neuroscience. 176: 296-307. PMID 21182904 DOI: 10.1016/j.neuroscience.2010.12.016  1
2011 Spear LP. Brain Development Encyclopedia of Adolescence. 1: 87-95. DOI: 10.1016/B978-0-12-373951-3.00006-5  1
2010 Anderson RI, Varlinskaya EI, Spear LP. Ethanol-induced conditioned taste aversion in male sprague-dawley rats: impact of age and stress. Alcoholism, Clinical and Experimental Research. 34: 2106-15. PMID 20860618 DOI: 10.1111/j.1530-0277.2010.01307.x  1
2010 Varlinskaya EI, Doremus-Fitzwater TL, Spear LP. Repeated restraint stress alters sensitivity to the social consequences of ethanol in adolescent and adult rats. Pharmacology, Biochemistry, and Behavior. 96: 228-35. PMID 20478326 DOI: 10.1016/j.pbb.2010.05.011  1
2010 Doremus-Fitzwater TL, Spear LP. Age-related differences in amphetamine sensitization: effects of prior drug or stress history on stimulant sensitization in juvenile and adult rats. Pharmacology, Biochemistry, and Behavior. 96: 198-205. PMID 20471409 DOI: 10.1016/j.pbb.2010.05.005  1
2010 Spear LP, Varlinskaya EI. Sensitivity to ethanol and other hedonic stimuli in an animal model of adolescence: implications for prevention science? Developmental Psychobiology. 52: 236-43. PMID 20222058 DOI: 10.1002/dev.20457  1
2010 Ramirez RL, Spear LP. Ontogeny of ethanol-induced motor impairment following acute ethanol: assessment via the negative geotaxis reflex in adolescent and adult rats. Pharmacology, Biochemistry, and Behavior. 95: 242-8. PMID 20138187 DOI: 10.1016/j.pbb.2010.01.013  1
2010 Varlinskaya EI, Spear LP. Sensitization to social anxiolytic effects of ethanol in adolescent and adult Sprague-Dawley rats after repeated ethanol exposure. Alcohol (Fayetteville, N.Y.). 44: 99-110. PMID 20113878 DOI: 10.1016/j.alcohol.2009.09.036  1
2010 Doremus-Fitzwater TL, Varlinskaya EI, Spear LP. Motivational systems in adolescence: possible implications for age differences in substance abuse and other risk-taking behaviors. Brain and Cognition. 72: 114-23. PMID 19762139 DOI: 10.1016/j.bandc.2009.08.008  1
2009 Windle M, Spear LP, Fuligni AJ, Angold A, Brown JD, Pine D, Smith GT, Giedd J, Dahl RE. Transitions into underage and problem drinking: summary of developmental processes and mechanisms: ages 10-15. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 32: 30-40. PMID 23104445  1
2009 Masten AS, Faden VB, Zucker RA, Spear LP. A developmental perspective on underage alcohol use. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 32: 3-15. PMID 23104443  1
2009 Vetter-O'Hagen C, Varlinskaya E, Spear L. Sex differences in ethanol intake and sensitivity to aversive effects during adolescence and adulthood Alcohol and Alcoholism. 44: 547-554. PMID 19767625 DOI: 10.1093/alcalc/agp048  1
2009 Willey AR, Varlinskaya EI, Spear LP. Social interactions and 50 kHz ultrasonic vocalizations in adolescent and adult rats. Behavioural Brain Research. 202: 122-9. PMID 19447288 DOI: 10.1016/j.bbr.2009.03.025  1
2009 Doremus-Fitzwater TL, Varlinskaya EI, Spear LP. Social and non-social anxiety in adolescent and adult rats after repeated restraint. Physiology & Behavior. 97: 484-94. PMID 19345235 DOI: 10.1016/j.physbeh.2009.03.025  1
2009 Doremus-Fitzwater TL, Varlinskaya EI, Spear LP. Effects of pretest manipulation on elevated plus-maze behavior in adolescent and adult male and female Sprague-Dawley rats. Pharmacology, Biochemistry, and Behavior. 92: 413-23. PMID 19344672 DOI: 10.1016/j.pbb.2009.01.006  1
2009 Varlinskaya EI, Spear LP. Ethanol-induced social facilitation in adolescent rats: role of endogenous activity at mu opioid receptors. Alcoholism, Clinical and Experimental Research. 33: 991-1000. PMID 19302088 DOI: 10.1111/j.1530-0277.2009.00920.x  1
2009 Wilmouth CE, Spear LP. Hedonic sensitivity in adolescent and adult rats: taste reactivity and voluntary sucrose consumption. Pharmacology, Biochemistry, and Behavior. 92: 566-73. PMID 19264093 DOI: 10.1016/j.pbb.2009.02.009  1
2009 Spear LP. Heightened stress responsivity and emotional reactivity during pubertal maturation: Implications for psychopathology. Development and Psychopathology. 21: 87-97. PMID 19144224 DOI: 10.1017/S0954579409000066  1
2008 Ristuccia RC, Spear LP. Autonomic responses to ethanol in adolescent and adult rats: a dose-response analysis. Alcohol (Fayetteville, N.Y.). 42: 623-9. PMID 18952397 DOI: 10.1016/j.alcohol.2008.08.002  1
2008 Pautassi RM, Myers M, Spear LP, Molina JC, Spear NE. Adolescent but not adult rats exhibit ethanol-mediated appetitive second-order conditioning. Alcoholism, Clinical and Experimental Research. 32: 2016-27. PMID 18782343 DOI: 10.1111/j.1530-0277.2008.00789.x  1
2008 Ristuccia RC, Spear LP. Adolescent and adult heart rate responses to self-administered ethanol. Alcoholism, Clinical and Experimental Research. 32: 1807-15. PMID 18657128 DOI: 10.1111/j.1530-0277.2008.00752.x  1
2008 Windle M, Spear LP, Fuligni AJ, Angold A, Brown JD, Pine D, Smith GT, Giedd J, Dahl RE. Transitions into underage and problem drinking: developmental processes and mechanisms between 10 and 15 years of age. Pediatrics. 121: S273-89. PMID 18381494 DOI: 10.1542/peds.2007-2243C  1
2008 Masten AS, Faden VB, Zucker RA, Spear LP. Underage drinking: a developmental framework. Pediatrics. 121: S235-51. PMID 18381492 DOI: 10.1542/peds.2007-2243A  1
2008 McCulloch M, Zhou X, Xu Y, Brunell S, Spear L. Determination of endocannabinoid receptor antagonist SR141716 (rimonabant) in plasma by liquid chromatograph tandem mass spectrometry Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences. 863: 258-265. PMID 18258497 DOI: 10.1016/j.jchromb.2008.01.020  1
2008 Varlinskaya EI, Spear LP. Social interactions in adolescent and adult Sprague-Dawley rats: impact of social deprivation and test context familiarity. Behavioural Brain Research. 188: 398-405. PMID 18242726 DOI: 10.1016/j.bbr.2007.11.024  1
2008 Spear L. Brain development and typical adolescent behaviour patterns (part 2) | Le développement du cerveau et les patterns de conduites typiques pendant l'adolescence (2 e partie) Psn. 6: 197-204. DOI: 10.1007/s11836-008-0070-2  1
2008 Spear L. Brain development and typical adolescent behaviour patterns (part 1) | Le développement du cerveau et les patterns de conduites typiques pendant l'adolescence (1re partie) Psn. 6: 149-154. DOI: 10.1007/s11836-008-0068-9  1
2007 Doremus-Fitzwater TL, Spear LP. Developmental differences in acute ethanol withdrawal in adolescent and adult rats. Alcoholism, Clinical and Experimental Research. 31: 1516-27. PMID 17760786 DOI: 10.1111/j.1530-0277.2007.00457.x  1
2007 Vetter CS, Doremus-Fitzwater TL, Spear LP. Time course of elevated ethanol intake in adolescent relative to adult rats under continuous, voluntary-access conditions. Alcoholism, Clinical and Experimental Research. 31: 1159-68. PMID 17511750 DOI: 10.1111/j.1530-0277.2007.00417.x  1
2007 Calabrese EJ, Bachmann KA, Bailer AJ, Bolger PM, Borak J, Cai L, Cedergreen N, Cherian MG, Chiueh CC, Clarkson TW, Cook RR, Diamond DM, Doolittle DJ, Dorato MA, Duke SO, ... ... Spear L, et al. Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicology and Applied Pharmacology. 222: 122-8. PMID 17459441 DOI: 10.1016/j.taap.2007.02.015  1
2007 Molina JC, Spear NE, Spear LP, Mennella JA, Lewis MJ. The International society for developmental psychobiology 39th annual meeting symposium: Alcohol and development: beyond fetal alcohol syndrome. Developmental Psychobiology. 49: 227-42. PMID 17380525 DOI: 10.1002/dev.20224  1
2007 Ristuccia RC, Hernandez M, Wilmouth CE, Spear LP. Differential expression of ethanol-induced hypothermia in adolescent and adult rats induced by pretest familiarization to the handling/injection procedure. Alcoholism, Clinical and Experimental Research. 31: 575-81. PMID 17374036 DOI: 10.1111/j.1530-0277.2007.00341.x  1
2007 Spear LP. Assessment of adolescent neurotoxicity: rationale and methodological considerations. Neurotoxicology and Teratology. 29: 1-9. PMID 17222532 DOI: 10.1016/j.ntt.2006.11.006  1
2007 Varlinskaya EI, Spear LP. Chronic tolerance to the social consequences of ethanol in adolescent and adult Sprague-Dawley rats. Neurotoxicology and Teratology. 29: 23-30. PMID 17055219 DOI: 10.1016/j.ntt.2006.08.009  1
2006 Wilmouth CE, Spear LP. Withdrawal from chronic nicotine in adolescent and adult rats. Pharmacology, Biochemistry, and Behavior. 85: 648-57. PMID 17173961 DOI: 10.1016/j.pbb.2006.10.021  1
2006 Varlinskaya EI, Spear LP. Ontogeny of acute tolerance to ethanol-induced social inhibition in Sprague-Dawley rats. Alcoholism, Clinical and Experimental Research. 30: 1833-44. PMID 17067347 DOI: 10.1111/j.1530-0277.2006.00220.x  1
2006 Miller MW, Spear LP. The alcoholism generator. Alcoholism, Clinical and Experimental Research. 30: 1466-9. PMID 16930208 DOI: 10.1111/j.1530-0277.2006.00177.x  1
2006 Brunell SC, Spear LP. Effects of acute ethanol or amphetamine administration on the acoustic startle response and prepulse inhibition in adolescent and adult rats. Psychopharmacology. 186: 579-86. PMID 16758242 DOI: 10.1007/s00213-006-0380-9  1
2006 Doremus TL, Varlinskaya EI, Spear LP. Factor analysis of elevated plus-maze behavior in adolescent and adult rats. Pharmacology, Biochemistry, and Behavior. 83: 570-7. PMID 16678892 DOI: 10.1016/j.pbb.2006.03.019  1
2006 Varlinskaya EI, Spear LP. Differences in the social consequences of ethanol emerge during the course of adolescence in rats: social facilitation, social inhibition, and anxiolysis. Developmental Psychobiology. 48: 146-61. PMID 16489593 DOI: 10.1002/dev.20124  1
2005 Spear LP, Varlinskaya EI. Low dose effects in psychopharmacology: ontogenetic considerations. Nonlinearity in Biology, Toxicology, Medicine. 3: 97-111. PMID 19330157 DOI: 10.2201/nonlin.003.01.006  0.88
2005 Ristuccia RC, Spear LP. Sensitivity and tolerance to autonomic effects of ethanol in adolescent and adult rats during repeated vapor inhalation sessions. Alcoholism, Clinical and Experimental Research. 29: 1809-20. PMID 16269910 DOI: 10.1097/01.alc.0000183010.72764.cd  1
2005 Doremus TL, Brunell SC, Rajendran P, Spear LP. Factors influencing elevated ethanol consumption in adolescent relative to adult rats. Alcoholism, Clinical and Experimental Research. 29: 1796-808. PMID 16269909 DOI: 10.1097/01.alc.0000183007.65998.aa  1
2005 Barron S, White A, Swartzwelder HS, Bell RL, Rodd ZA, Slawecki CJ, Ehlers CL, Levin ED, Rezvani AH, Spear LP. Adolescent vulnerabilities to chronic alcohol or nicotine exposure: findings from rodent models. Alcoholism, Clinical and Experimental Research. 29: 1720-5. PMID 16205372 DOI: 10.1097/01.alc.0000179220.79356.e5  1
2005 Brunell SC, Spear LP. Effect of stress on the voluntary intake of a sweetened ethanol solution in pair-housed adolescent and adult rats. Alcoholism, Clinical and Experimental Research. 29: 1641-53. PMID 16205364 DOI: 10.1097/01.alc.0000179382.64752.13  1
2005 Spear LP, Varlinskaya EI. Adolescence. Alcohol sensitivity, tolerance, and intake. Recent Developments in Alcoholism : An Official Publication of the American Medical Society On Alcoholism, the Research Society On Alcoholism, and the National Council On Alcoholism. 17: 143-59. PMID 15789864  1
2004 Douglas LA, Varlinskaya EI, Spear LP. Rewarding properties of social interactions in adolescent and adult male and female rats: impact of social versus isolate housing of subjects and partners. Developmental Psychobiology. 45: 153-62. PMID 15505797 DOI: 10.1002/dev.20025  1
2004 Wilmouth CE, Spear LP. Adolescent and adult rats' aversion to flavors previously paired with nicotine. Annals of the New York Academy of Sciences. 1021: 462-4. PMID 15251930 DOI: 10.1196/annals.1308.065  1
2004 Varlinskaya EI, Spear LP. Changes in sensitivity to ethanol-induced social facilitation and social inhibition from early to late adolescence. Annals of the New York Academy of Sciences. 1021: 459-61. PMID 15251929 DOI: 10.1196/annals.1308.064  1
2004 Ristuccia RC, Spear LP. Adolescent ethanol sensitivity: hypothermia and acute tolerance. Annals of the New York Academy of Sciences. 1021: 445-7. PMID 15251926 DOI: 10.1196/annals.1308.061  1
2004 Rajendran P, Spear LP. The effects of ethanol on spatial and nonspatial memory in adolescent and adult rats studied using an appetitive paradigm. Annals of the New York Academy of Sciences. 1021: 441-4. PMID 15251925 DOI: 10.1196/annals.1308.060  1
2004 Doremus TL, Varlinskaya EI, Spear LP. Age-related differences in elevated plus maze behavior between adolescent and adult rats. Annals of the New York Academy of Sciences. 1021: 427-30. PMID 15251922 DOI: 10.1196/annals.1308.057  1
2004 Spear LP. Adolescence and the trajectory of alcohol use: introduction to part VI. Annals of the New York Academy of Sciences. 1021: 202-5. PMID 15251890 DOI: 10.1196/annals.1308.025  1
2004 Spear LP. Adolescent brain development and animal models. Annals of the New York Academy of Sciences. 1021: 23-6. PMID 15251870 DOI: 10.1196/annals.1308.002  1
2004 Silveri MM, Spear LP. The effects of NMDA and GABAA pharmacological manipulations on acute and rapid tolerance to ethanol during ontogeny. Alcoholism, Clinical and Experimental Research. 28: 884-94. PMID 15201631  1
2004 Silveri MM, Spear LP. Characterizing the ontogeny of ethanol-associated increases in corticosterone. Alcohol (Fayetteville, N.Y.). 32: 145-55. PMID 15163565 DOI: 10.1016/j.alcohol.2003.12.004  1
2004 Varlinskaya EI, Spear LP. Acute ethanol withdrawal (hangover) and social behavior in adolescent and adult male and female Sprague-Dawley rats. Alcoholism, Clinical and Experimental Research. 28: 40-50. PMID 14745301 DOI: 10.1097/01.ALC.0000108655.51087.DF  1
2004 Dahl R, Spear LP, Kelley A, Shaikh R, Clayton R. Adolescent brain development: Vulnerabilities and opportunities - Preface Annals of the New York Academy of Sciences. 1021: xi-xii. DOI: 10.1196/annals.1308.067  1
2003 Douglas LA, Varlinskaya EI, Spear LP. Novel-object place conditioning in adolescent and adult male and female rats: effects of social isolation. Physiology & Behavior. 80: 317-25. PMID 14637231 DOI: 10.1016/j.physbeh.2003.08.003  1
2003 Doremus TL, Brunell SC, Varlinskaya EI, Spear LP. Anxiogenic effects during withdrawal from acute ethanol in adolescent and adult rats. Pharmacology, Biochemistry, and Behavior. 75: 411-8. PMID 12873633 DOI: 10.1016/S0091-3057(03)00134-5  1
2002 Spear LP. Alcohol's effects on adolescents. Alcohol Research & Health : the Journal of the National Institute On Alcohol Abuse and Alcoholism. 26: 287-91. PMID 12875039  1
2002 Varlinskaya EI, Spear LP. Acute effects of ethanol on social behavior of adolescent and adult rats: role of familiarity of the test situation. Alcoholism, Clinical and Experimental Research. 26: 1502-11. PMID 12394283 DOI: 10.1097/01.ALC.0000034033.95701.E3  1
2002 Vastola BJ, Douglas LA, Varlinskaya EI, Spear LP. Nicotine-induced conditioned place preference in adolescent and adult rats. Physiology & Behavior. 77: 107-14. PMID 12213508 DOI: 10.1016/S0031-9384(02)00818-1  1
2002 Spear LP. The adolescent brain and the college drinker: biological basis of propensity to use and misuse alcohol. Journal of Studies On Alcohol. Supplement. 71-81. PMID 12022731  1
2002 Spear LP, Silveri MM, Casale M, Katovic NM, Campbell JO, Douglas LA. Cocaine and development: a retrospective perspective. Neurotoxicology and Teratology. 24: 321-7. PMID 12009487 DOI: 10.1016/S0892-0362(02)00194-0  1
2002 Silveri MM, Spear LP. The effects of NMDA and GABAA pharmacological manipulations on ethanol sensitivity in immature and mature animals. Alcoholism, Clinical and Experimental Research. 26: 449-56. PMID 11981119  1
2002 Kraebel KS, Brasser SM, Campbell JO, Spear LP, Spear NE. Developmental differences in temporal patterns and potentiation of isolation-induced ultrasonic vocalizations: influence of temperature variables. Developmental Psychobiology. 40: 147-59. PMID 11857329 DOI: 10.1002/dev.10022  1
2001 Silveri MM, Spear LP. Acute, rapid, and chronic tolerance during ontogeny: observations when equating ethanol perturbation across age. Alcoholism, Clinical and Experimental Research. 25: 1301-8. PMID 11584149  1
2001 Cheslock SJ, Varlinskaya EI, Petrov ES, Silveri MM, Spear LP, Spear NE. Ethanol as a reinforcer in the newborn's first suckling experience. Alcoholism, Clinical and Experimental Research. 25: 391-402. PMID 11290850  1
2001 Varlinskaya EI, Spear LP, Spear NE. Acute effects of ethanol on behavior of adolescent rats: role of social context. Alcoholism, Clinical and Experimental Research. 25: 377-85. PMID 11290848  1
2000 Campbell JO, Bliven TD, Silveri MM, Snyder KJ, Spear LP. Effects of prenatal cocaine on behavioral adaptation to chronic stress in adult rats. Neurotoxicology and Teratology. 22: 845-50. PMID 11120390 DOI: 10.1016/S0892-0362(00)00104-5  1
2000 Cheslock SJ, Varlinskaya EI, Silveri MM, Petrov ES, Spear LP, Spear NE. Acute effects of ethanol and the first suckling episode in the newborn rat. Alcoholism, Clinical and Experimental Research. 24: 996-1002. PMID 10924002  1
2000 Spear LP. The adolescent brain and age-related behavioral manifestations. Neuroscience and Biobehavioral Reviews. 24: 417-63. PMID 10817843 DOI: 10.1016/S0149-7634(00)00014-2  1
2000 Campbell JO, Wood RD, Spear LP. Cocaine and morphine-induced place conditioning in adolescent and adult rats. Physiology & Behavior. 68: 487-93. PMID 10713288 DOI: 10.1016/S0031-9384(99)00225-5  1
2000 Silveri MM, Spear LP. Ontogeny of ethanol elimination and ethanol-induced hypothermia. Alcohol (Fayetteville, N.Y.). 20: 45-53. PMID 10680716 DOI: 10.1016/S0741-8329(99)00055-5  1
2000 Spear LP. Neurobehavioral changes in adolescence Current Directions in Psychological Science. 9: 111-114.  1
1999 Katovic NM, Gresack JE, Spear LP. Schedule-induced polydipsia: gender-specific effects and consequences of prenatal cocaine and postnatal handling. Pharmacology, Biochemistry, and Behavior. 64: 695-704. PMID 10593192 DOI: 10.1016/S0091-3057(99)00152-5  1
1999 Varlinskaya EI, Spear LP, Spear NE. Social behavior and social motivation in adolescent rats: role of housing conditions and partner's activity. Physiology & Behavior. 67: 475-82. PMID 10549884 DOI: 10.1016/S0031-9384(98)00285-6  1
1999 Hecht GS, Spear NE, Spear LP. Changes in progressive ratio responding for intravenous cocaine throughout the reproductive process in female rats. Developmental Psychobiology. 35: 136-45. PMID 10461127 DOI: 10.1002/(SICI)1098-2302(199909)35:2<136::AID-DEV6>3.0.CO;2-K  1
1999 Silveri MM, Spear LP. Ontogeny of rapid tolerance to the hypnotic effects of ethanol. Alcoholism, Clinical and Experimental Research. 23: 1180-4. PMID 10443983  1
1999 Campbell JO, Fogarty JA, Spear LP. Inhibition of nitric oxide synthesis with L-NAME suppresses isolation-induced ultrasounds in rat pups. Pharmacology, Biochemistry, and Behavior. 63: 45-53. PMID 10340523 DOI: 10.1016/S0091-3057(98)00233-0  1
1999 Campbell J, Spear LP. Effects of early handling on amphetamine-induced locomotor activation and conditioned place preference in the adult rat. Psychopharmacology. 143: 183-9. PMID 10326781 DOI: 10.1007/s002130050934  1
1998 Wood RD, Tirelli E, Snyder KJ, Heyser CJ, LaRocca TM, Spear LP. Evidence for behavioral sensitization to cocaine in preweanling rat pups. Psychopharmacology. 138: 114-23. PMID 9718280 DOI: 10.1007/s002130050653  1
1998 Snyder KJ, Katovic NM, Spear LP. Longevity of the expression of behavioral sensitization to cocaine in preweanling rats. Pharmacology, Biochemistry, and Behavior. 60: 909-14. PMID 9700975 DOI: 10.1016/S0091-3057(98)00078-1  1
1998 Spear LP, Campbell J, Snyder K, Silveri M, Katovic N. Animal behavior models. Increased sensitivity to stressors and other environmental experiences after prenatal cocaine exposure. Annals of the New York Academy of Sciences. 846: 76-88. PMID 9668399 DOI: 10.1111/j.1749-6632.1998.tb09728.x  1
1998 Silveri MM, Spear LP. Decreased sensitivity to the hypnotic effects of ethanol early in ontogeny. Alcoholism, Clinical and Experimental Research. 22: 670-6. PMID 9622449 DOI: 10.1111/j.1530-0277.1998.tb04310.x  1
1998 Wood RD, Spear LP. Prenatal cocaine alters social competition of infant, adolescent, and adult rats. Behavioral Neuroscience. 112: 419-31. PMID 9588488 DOI: 10.1037/0735-7044.112.2.419  1
1998 Hecht GS, Spear NE, Spear LP. Alterations in the reinforcing efficacy of cocaine in adult rats following prenatal exposure to cocaine. Behavioral Neuroscience. 112: 410-8. PMID 9588487 DOI: 10.1037/0735-7044.112.2.410  1
1998 Bannoura MD, Kraebel KS, Spear LP, Spear NE. Effects of preweanling ethanol odor exposure on ethanol preference. Alcohol (Fayetteville, N.Y.). 15: 213-7. PMID 9539378 DOI: 10.1016/S0741-8329(97)00122-5  1
1997 Goodwin GA, Bliven T, Kuhn C, Francis R, Spear LP. Immediate early gene expression to examine neuronal activity following acute and chronic stressors in rat pups: examination of neurophysiological alterations underlying behavioral consequences of prenatal cocaine exposure. Physiology & Behavior. 61: 895-902. PMID 9177564 DOI: 10.1016/S0031-9384(96)00615-4  1
1996 Spear LP, File SE. Methodological considerations in neurobehavioral teratology. Pharmacology, Biochemistry, and Behavior. 55: 455-7. PMID 8981575 DOI: 10.1016/S0091-3057(96)00272-9  1
1996 Spear LP. Assessment of the effects of developmental toxicants: pharmacological and stress vulnerability of offspring. Nida Research Monograph. 164: 125-45. PMID 8809870  1
1996 Specht SM, Burright RG, Spear LP. Behavioral components of milk-induced activation in neonatal rat pups. Perceptual and Motor Skills. 82: 903-11. PMID 8774030 DOI: 10.2466/pms.1996.82.3.903  1
1996 McKinzie DL, Lee JS, McKinzie JH, Spear LP, Spear NE. Ontogenetic differences in ethanol-induced impairment of context and CS learning Psychobiology. 24: 306-313.  1
1995 Wood RD, Molina VA, Wagner JM, Spear LP. Play behavior and stress responsivity in periadolescent offspring exposed prenatally to cocaine. Pharmacology, Biochemistry, and Behavior. 52: 367-74. PMID 8577803 DOI: 10.1016/0091-3057(95)00120-L  1
1995 Heyser CJ, Spear NE, Spear LP. Effects of prenatal exposure to cocaine on Morris water maze performance in adult rats. Behavioral Neuroscience. 109: 734-43. PMID 7576217 DOI: 10.1037/0735-7044.109.4.734  1
1995 Goodwin GA, Rajachandran L, Moody CA, Francis R, Kuhn CM, Spear LP. Effects of prenatal cocaine exposure on haloperidol-induced increases in prolactin release and dopamine turnover in weanling, periadolescent, and adult offspring. Neurotoxicology and Teratology. 17: 507-14. PMID 7565497 DOI: 10.1016/0892-0362(95)00010-O  1
1995 Laviola G, Wood RD, Kuhn C, Francis R, Spear LP. Cocaine sensitization in periadolescent and adult rats. The Journal of Pharmacology and Experimental Therapeutics. 275: 345-57. PMID 7562570  1
1994 Leskawa KC, Jackson GH, Moody CA, Spear LP. Cocaine exposure during pregnancy affects rat neonate and maternal brain glycosphingolipids. Brain Research Bulletin. 33: 195-8. PMID 8275339 DOI: 10.1016/0361-9230(94)90251-8  1
1994 Spear LP, Frambes NA, Goodwin GA, Moody CA. The 5-HT1A agonist 8-OH-DPAT increases attachment maintenance but decreases suckling-related intake in 17-18-day-old rat pups. Pharmacology, Biochemistry, and Behavior. 47: 133-9. PMID 8115414 DOI: 10.1016/0091-3057(94)90122-8  1
1994 Goodwin GA, Molina VA, Spear LP. Repeated exposure of rat pups to isolation attenuates isolation-induced ultrasonic vocalization rates: reversal with naltrexone. Developmental Psychobiology. 27: 53-64. PMID 8112488 DOI: 10.1002/dev.420270106  1
1994 Molina VA, Wagner JM, Spear LP. The behavioral response to stress is altered in adult rats exposed prenatally to cocaine. Physiology & Behavior. 55: 941-5. PMID 8022916 DOI: 10.1016/0031-9384(94)90083-3  1
1994 Molina VA, Heyser CJ, Spear LP. Chronic variable stress enhances the stimulatory action of a low dose of morphine: reversal by desipramine. European Journal of Pharmacology. 260: 57-64. PMID 7957627 DOI: 10.1016/0014-2999(94)90009-4  1
1994 de Bartolomeis A, Austin MC, Goodwin GA, Spear LP, Pickar D, Crawley JN. Dopaminergic and peptidergic mRNA levels in juvenile rat brain after prenatal cocaine treatment. Brain Research. Molecular Brain Research. 21: 321-32. PMID 7909578 DOI: 10.1016/0169-328X(94)90263-1  1
1994 Heyser CJ, Rajachandran L, Spear NE, Spear LP. Responsiveness to cocaine challenge in adult rats following prenatal exposure to cocaine. Psychopharmacology. 116: 45-55. PMID 7862930 DOI: 10.1007/BF02244870  1
1994 McKinzie DL, Lee J, Bronfen JH, Spear LP, Spear NE. Context and tone conditioning are selectively impaired by ethanol in the preweanling rat: effects of dose and time of administration. Behavioral and Neural Biology. 62: 201-9. PMID 7857242 DOI: 10.1016/S0163-1047(05)80018-4  1
1994 Molina VA, Heyser CJ, Spear LP. Chronic variable stress or chronic morphine facilitates immobility in a forced swim test: reversal by naloxone. Psychopharmacology. 114: 433-40. PMID 7855201 DOI: 10.1007/BF02249333  1
1994 Heyser CJ, McKinzie DL, Athalie F, Spear NE, Spear LP. Effects of prenatal exposure to cocaine on heart rate and nonassociative learning and retention in infant rats. Teratology. 49: 470-8. PMID 7747268 DOI: 10.1002/tera.1420490607  0.84
1993 Spear LP, Heyser CJ. Is use of a cellulose-diluted diet a viable alternative to pair-feeding? Neurotoxicology and Teratology. 15: 85-9. PMID 8510611 DOI: 10.1016/0892-0362(93)90066-W  1
1993 Hunt PS, Molina JC, Rajachandran L, Spear LP, Spear NE. Chronic administration of alcohol in the developing rat: expression of functional tolerance and alcohol olfactory aversions. Behavioral and Neural Biology. 59: 87-99. PMID 8476387 DOI: 10.1016/0163-1047(93)90795-J  1
1993 Robinson SR, Moody CA, Spear LP, Smotherman WP. Effects of dopamine and kappa opioid receptors on fetal responsiveness to perioral stimuli. Developmental Psychobiology. 26: 37-50. PMID 8382637 DOI: 10.1002/dev.420260104  1
1993 Smotherman WP, Moody CA, Spear LP, Robinson SR. Fetal behavior and the endogenous opioid system: D1 dopamine receptor interactions with the kappa opioid system. Physiology & Behavior. 53: 191-7. PMID 8381974 DOI: 10.1016/0031-9384(93)90030-J  1
1993 Hunt PS, Kraebel KS, Rabine H, Spear LP, Spear NE. Enhanced ethanol intake in preweanling rats following exposure to ethanol in a nursing context. Developmental Psychobiology. 26: 133-53. PMID 8314435 DOI: 10.1002/dev.420260302  1
1993 Goodwin GA, Moody CA, Spear LP. Prenatal cocaine exposure increases the behavioral sensitivity of neonatal rat pups to ligands active at opiate receptors. Neurotoxicology and Teratology. 15: 425-31. PMID 8302244 DOI: 10.1016/0892-0362(93)90060-2  1
1993 Rajachandran L, Spear NE, Spear LP. Effects of the combined administration of the 5-HT3 antagonist MDL 72222 and ethanol on conditioning in the periadolescent and adult rat. Pharmacology, Biochemistry, and Behavior. 46: 535-42. PMID 8278430 DOI: 10.1016/0091-3057(93)90541-Z  1
1993 Spear LP. Missing pieces of the puzzle complicate conclusions about cocaine's neurobehavioral toxicity in clinical populations: importance of animal models. Neurotoxicology and Teratology. 15: 307-9; discussion 31. PMID 8277924 DOI: 10.1016/0892-0362(93)90031-I  1
1993 Moody CA, Robinson SR, Spear LP, Smotherman WP. Fetal behavior and the dopamine system: activity effects of D1 and D2 receptor manipulations. Pharmacology, Biochemistry, and Behavior. 44: 843-50. PMID 8097042 DOI: 10.1016/0091-3057(93)90015-L  1
1993 Chen WJ, Spear LP, Spear NE. Disruptive influence of norepinephrine depletion on sensory preconditioning, but not first-order conditioning, in preweanling rats. Behavioral and Neural Biology. 60: 110-7. PMID 7509594 DOI: 10.1016/0163-1047(93)90187-M  1
1993 Heyser CJ, Spear NE, Spear LP. Effects of prenatal exposure to cocaine on discrimination learning in adult rats Nida Research Monograph Series. 116.  1
1992 Heyser CJ, Miller JS, Spear NE, Spear LP. Prenatal exposure to cocaine disrupts cocaine-induced conditioned place preference in rats. Neurotoxicology and Teratology. 14: 57-64. PMID 1593980 DOI: 10.1016/0892-0362(92)90029-A  1
1992 Chen WJ, Spear LP, Spear NE. Enhancement of sensory preconditioning by a moderate dose of ethanol in infant and juvenile rats. Behavioral and Neural Biology. 57: 44-57. PMID 1567333 DOI: 10.1016/0163-1047(92)90746-Q  1
1992 Akbari HM, Kramer HK, Whitaker-Azmitia PM, Spear LP, Azmitia EC. Prenatal cocaine exposure disrupts the development of the serotonergic system. Brain Research. 572: 57-63. PMID 1535274 DOI: 10.1016/0006-8993(92)90450-N  1
1992 Heyser CJ, Goodwin GA, Moody CA, Spear LP. Prenatal cocaine exposure attenuates cocaine-induced odor preference in infant rats. Pharmacology, Biochemistry, and Behavior. 42: 169-73. PMID 1528939 DOI: 10.1016/0091-3057(92)90461-N  1
1992 Minabe Y, Ashby CR, Heyser C, Spear LP, Wang RY. The effects of prenatal cocaine exposure on spontaneously active midbrain dopamine neurons in adult male offspring: an electrophysiological study. Brain Research. 586: 152-6. PMID 1511345 DOI: 10.1016/0006-8993(92)91387-T  1
1992 Goodwin GA, Heyser CJ, Moody CA, Rajachandran L, Molina VA, Arnold HM, McKinzie DL, Spear NE, Spear LP. A fostering study of the effects of prenatal cocaine exposure: II. Offspring behavioral measures. Neurotoxicology and Teratology. 14: 423-32. PMID 1488037 DOI: 10.1016/0892-0362(92)90053-D  1
1992 Heyser CJ, Molina VA, Spear LP. A fostering study of the effects of prenatal cocaine exposure: I. Maternal behaviors. Neurotoxicology and Teratology. 14: 415-21. PMID 1488036 DOI: 10.1016/0892-0362(92)90052-C  1
1992 Heyser CJ, Spear NE, Spear LP. Effects of prenatal exposure to cocaine on conditional discrimination learning in adult rats. Behavioral Neuroscience. 106: 837-45. PMID 1445659 DOI: 10.1037/0735-7044.106.5.837  1
1992 Moody CA, Frambes NA, Spear LP. Psychopharmacological responsiveness to the dopamine agonist quinpirole in normal weanlings and in weanling offspring exposed gestationally to cocaine. Psychopharmacology. 108: 256-62. PMID 1355920 DOI: 10.1007/BF02245109  1
1992 Eilam D, Szechtman H, Spear LP. Quinpirole alters quadruped activity in rats from the second postnatal week. Developmental Psychobiology. 25: 275-89. PMID 1352505 DOI: 10.1002/dev.420250405  1
1992 Moody CA, Spear LP. Effects of acute dopamine depletion on responsiveness to D1 and D2 receptor agonists in infant and weanling rat pups. Psychopharmacology. 107: 39-49. PMID 1350350 DOI: 10.1007/BF02244963  1
1992 Moody CA, Spear LP. Ontogenetic differences in the psychopharmacological responses to separate and combined stimulation of D1 and D2 dopamine receptors during the neonatal to weanling age period. Psychopharmacology. 106: 161-8. PMID 1347951 DOI: 10.1007/BF02801967  1
1992 Zigmond MJ, Spear LP. Neuroscience training in the USA and Canada: observations and suggestions. Trends in Neurosciences. 15: 379-83. PMID 1279858 DOI: 10.1016/0166-2236(92)90183-9  1
1991 Spear LP, Frambes NA, Goodwin G. Low doses of the 5-HT1A receptor agonist 8-OH-DPAT increase ingestive behavior in late preweanling and postweanling, but not neonatal rat pups. European Journal of Pharmacology. 203: 9-15. PMID 1839148 DOI: 10.1016/0014-2999(91)90784-N  1
1991 Rajachandran L, Goodwin GA, Spear LP. Psychopharmacological effects of MK-801 in infant and preweanling rat pups. Pharmacology, Biochemistry, and Behavior. 40: 291-5. PMID 1805233 DOI: 10.1016/0091-3057(91)90555-G  1
1991 Hunt PS, Spear LP, Spear NE. An ontogenetic comparison of ethanol-mediated taste aversion learning and ethanol-induced hypothermia in preweanling rats. Behavioral Neuroscience. 105: 971-83. PMID 1777109 DOI: 10.1037/0735-7044.105.6.971  1
1991 Chen WJ, Lariviere NA, Heyser CJ, Spear LP, Spear NE. Age-related differences in sensory conditioning in rats. Developmental Psychobiology. 24: 307-26. PMID 1752352 DOI: 10.1002/dev.420240502  1
1991 Clow DW, Hammer RP, Kirstein CL, Spear LP. Gestational cocaine exposure increases opiate receptor binding in weanling offspring. Brain Research. Developmental Brain Research. 59: 179-85. PMID 1655306 DOI: 10.1016/0165-3806(91)90098-4  1
1990 Heyser CJ, Chen WJ, Miller J, Spear NE, Spear LP. Prenatal cocaine exposure induces deficits in Pavlovian conditioning and sensory preconditioning among infant rat pups. Behavioral Neuroscience. 104: 955-63. PMID 2285493 DOI: 10.1037/0735-7044.104.6.955  1
1990 Kirstein CL, Traber J, Gispen WH, Spear LP. ACTH-induced behaviors and their modulation by serotonergic agonists differ in neonatal and weanling rat pups. Psychopharmacology. 100: 151-8. PMID 2154832 DOI: 10.1007/BF02244398  1
1990 Scalzo FM, Ali SF, Frambes NA, Spear LP. Weanling rats exposed prenatally to cocaine exhibit an increase in striatal D2 dopamine binding associated with an increase in ligand affinity. Pharmacology, Biochemistry, and Behavior. 37: 371-3. PMID 2150444 DOI: 10.1016/0091-3057(90)90350-Q  1
1990 Frambes NA, Kirstein CL, Moody CA, Spear LP. 5-HT1A, 5-HT1B and 5-HT2 receptor agonists induce differential behavioral responses in preweanling rat pups. European Journal of Pharmacology. 182: 9-17. PMID 2144825 DOI: 10.1016/0014-2999(90)90488-R  1
1990 Hunt PS, Molina JC, Spear LP, Spear NE. Ethanol-mediated taste aversions and state-dependency in preweanling (16-day-old) rats. Behavioral and Neural Biology. 54: 300-22. PMID 2078162 DOI: 10.1016/0163-1047(90)90650-U  1
1990 Enters EK, Specht SM, Spear LP. Injection of 5,7-dihydroxytryptamine into the B3 raphe region of neonatal rat pups induces hyperalgesia but only slight alterations in ingestion-related behaviors. Behavioral and Neural Biology. 53: 244-57. PMID 1691912 DOI: 10.1016/0163-1047(90)90475-L  1
1990 Hammer RP, Clow DW, Spear LP. Opioid involvement in the rewarding effects of chronic cocaine. Nida Research Monograph. 105: 182-8. PMID 1652069  1
1989 Spear LP, Kirstein CL, Frambes NA. Cocaine effects on the developing central nervous system: behavioral, psychopharmacological, and neurochemical studies. Annals of the New York Academy of Sciences. 562: 290-307. PMID 2742285  1
1989 Specht SM, Spear LP. Histamine-elicited drinking in weanling and adult rats. Physiology & Behavior. 45: 63-70. PMID 2727143 DOI: 10.1016/0031-9384(89)90166-2  1
1989 Spear LP, Kirstein CL, Bell J, Yoottanasumpun V, Greenbaum R, O'Shea J, Hoffmann H, Spear NE. Effects of prenatal cocaine exposure on behavior during the early postnatal period. Neurotoxicology and Teratology. 11: 57-63. PMID 2725442 DOI: 10.1016/0892-0362(89)90086-X  1
1989 Spear LP, Specht SM, Kirstein CL, Kuhn CM. Anterior and posterior, but not cheek, intraoral cannulation procedures elevate serum corticosterone levels in neonatal rat pups. Developmental Psychobiology. 22: 401-11. PMID 2721821 DOI: 10.1002/dev.420220407  1
1989 Spear LP, Kirstein CL, Frambes NA, Moody CA. Neurobehavioral teratogenicity of gestational cocaine exposure. Nida Research Monograph. 95: 232-8. PMID 2640970  1
1989 Spear LP, Frambes NA, Kirstein CL. Fetal and maternal brain and plasma levels of cocaine and benzoylecgonine following chronic subcutaneous administration of cocaine during gestation in rats. Psychopharmacology. 97: 427-31. PMID 2498938 DOI: 10.1007/BF00439542  1
1988 Enters EK, Spear LP. Ontogenetic transitions in the psychopharmacological response to serotonergic manipulations. Psychopharmacology. 96: 161-8. PMID 3148141  0.8
1988 Linville DG, Spear LP. Cholinergic influences on wall climbing and its ontogenetic decline. Psychopharmacology. 95: 200-7. PMID 3137598 DOI: 10.1007/BF00174510  1
1988 Kirstein CL, Spear LP. 5-HT1A, 5-HT1B and 5-HT2 receptor agonists induce differential behavioral responses in neonatal rat pups. European Journal of Pharmacology. 150: 339-45. PMID 2970973 DOI: 10.1016/0014-2999(88)90016-7  1
1988 Enters EK, Spear LP. Serotonergic and opiate interactions in the modulation of drug- and environmental-induced analgesia in the neonatal rat pup. Behavioral and Neural Biology. 50: 80-97. PMID 2840888  0.8
1987 Molina JC, Hoffmann H, Spear LP, Spear NE. Sensorimotor maturation and alcohol responsiveness in rats prenatally exposed to alcohol during gestational day 8. Neurotoxicology and Teratology. 9: 121-8. PMID 3657747 DOI: 10.1016/0892-0362(87)90088-2  1
1987 Molina JC, Serwatka J, Enters EK, Spear LP, Spear NE. Acute alcohol intoxication disrupts brightness but not olfactory conditioning in preweanling rats. Behavioral Neuroscience. 101: 846-53. PMID 3426798 DOI: 10.1037/0735-7044.101.6.846  1
1986 Spear LP, Penson J, Linville DG. GABA and behavioral inhibition in the neonatal rat pup. Psychopharmacology. 90: 106-11. PMID 3094052 DOI: 10.1007/BF00172880  1
1985 Scalzo FM, Spear LP. Chronic haloperidol during development attenuates dopamine autoreceptor function in striatal and mesolimbic brain regions of young and older adult rats. Psychopharmacology. 85: 271-6. PMID 3923514 DOI: 10.1007/BF00428186  1
1985 Emerich DF, Scalzo FM, Enters EK, Spear NE, Spear LP. Effects of 6-hydroxydopamine-induced catecholamine depletion on shock-precipitated wall climbing of infant rat pups. Developmental Psychobiology. 18: 215-27. PMID 3921418 DOI: 10.1002/dev.420180303  1
1985 Spear LP, Enters EK, Aswad MA, Louzan M. Drug and environmentally induced manipulations of the opiate and serotonergic systems alter nociception in neonatal rat pups. Behavioral and Neural Biology. 44: 1-22. PMID 3841749  0.8
1985 Spear LP, Enters EK, Linville DG. Age-specific behaviors as tools for examining teratogen-induced neural alterations. Neurobehavioral Toxicology and Teratology. 7: 691-5. PMID 3835468  1
1985 Molina JC, Serwatka J, Spear LP, Spear NE. Differential ethanol olfactory experiences affect ethanol ingestion in preweanlings but not in older rats. Behavioral and Neural Biology. 44: 90-100. PMID 3834925 DOI: 10.1016/S0163-1047(85)91226-9  1
1985 Ristine LA, Spear LP. Is there a "serotonergic syndrome" in neonatal rat pups? Pharmacology, Biochemistry, and Behavior. 22: 265-9. PMID 2858868  0.01
1985 Spear LP, Scalzo FM. Ontogenetic alterations in the effects of food and/or maternal deprivation on 5-HT, 5-HIAA and 5-HIAA/5-HT ratios. Brain Research. 350: 143-57. PMID 2580603 DOI: 10.1016/0165-3806(85)90258-5  1
1984 Molina JC, Moyano HF, Spear LP, Spear NE. Acute alcohol exposure during gestational day 8 in the rat: effects upon physical and behavioral parameters. Alcohol (Fayetteville, N.Y.). 1: 459-64. PMID 6543578 DOI: 10.1016/0741-8329(84)90022-3  1
1984 Barrett BA, Rizzo T, Spear NE, Spear LP. Stimulus selection in passive avoidance learning and retention: weanling, periadolescent, and young adult rats. Behavioral and Neural Biology. 42: 23-32. PMID 6508690 DOI: 10.1016/S0163-1047(84)90388-1  1
1982 Smith GJ, Spear LP, Spear NE. Detection of cholinergic mediation of behavior in 7-, 9-, and 12-day old rat pups. Pharmacology, Biochemistry, and Behavior. 16: 805-9. PMID 7089037 DOI: 10.1016/0091-3057(82)90239-8  1
1982 Barrett BA, Caza P, Spear NE, Spear LP. Wall climbing, odors from the home nest and catecholaminergic activity in rat pups. Physiology & Behavior. 29: 501-7. PMID 6891075 DOI: 10.1016/0031-9384(82)90273-6  1
1982 Caza PA, Spear LP. Pharmacological manipulation of milk-induced behaviors in three-day-old rat pups. Pharmacology, Biochemistry, and Behavior. 16: 481-6. PMID 6123119  0.68
1980 Caza PA, Spear LP. Ontogenesis of morphine-induced behavior in the rat. Pharmacology, Biochemistry, and Behavior. 13: 45-50. PMID 7190709  0.68
1979 Infurna RN, Spear LP. Developmental changes in amphetamine-induced taste aversions. Pharmacology, Biochemistry, and Behavior. 11: 31-5. PMID 493297  0.48
1979 Smith GJ, Spear LP, Spear NE. Ontogeny of cholinergic mediation of behaviors in the rat. Journal of Comparative and Physiological Psychology. 93: 636-47. PMID 479401  1
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