Christiane Frahm - Publications

Affiliations: 
Department of Neurology, Jena 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Baumann A, Hernández-Arriaga A, Brandt A, Sánchez V, Nier A, Jung F, Kehm R, Höhn A, Grune T, Frahm C, Witte OW, Camarinha-Silva A, Bergheim I. Microbiota profiling in aging-associated inflammation and liver degeneration. International Journal of Medical Microbiology : Ijmm. 311: 151500. PMID 33813306 DOI: 10.1016/j.ijmm.2021.151500  0.6
2021 Graf J, Zhang C, Marguet SL, Herrmann T, Flossmann T, Hinsch R, Rahmati V, Guenther M, Frahm C, Urbach A, Neves RM, Witte OW, Kiebel SJ, Isbrandt D, Hübner CA, et al. A limited role of NKCC1 in telencephalic glutamatergic neurons for developing hippocampal network dynamics and behavior. Proceedings of the National Academy of Sciences of the United States of America. 118. PMID 33782119 DOI: 10.1073/pnas.2014784118  0.6
2020 Srivastava A, Barth E, Ermolaeva MA, Guenther M, Frahm C, Marz M, Witte OW. Tissue-specific Gene Expression Changes Are Associated with Aging in Mice. Genomics, Proteomics & Bioinformatics. PMID 33309863 DOI: 10.1016/j.gpb.2020.12.001  0.6
2019 Barth E, Srivastava A, Stojiljkovic M, Frahm C, Axer H, Witte OW, Marz M. Conserved aging-related signatures of senescence and inflammation in different tissues and species. Aging. 11. PMID 31606727 DOI: 10.18632/aging.102345  0.6
2019 Hernández-Arriaga A, Baumann A, Witte OW, Frahm C, Bergheim I, Camarinha-Silva A. Changes in Oral Microbial Ecology of C57BL/6 Mice at Different Ages Associated with Sampling Methodology. Microorganisms. 7. PMID 31443509 DOI: 10.3390/microorganisms7090283  0.6
2019 Irizar PA, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, et al. Publisher Correction: Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly. Nature Communications. 10: 2459. PMID 31150008 DOI: 10.1038/S41467-019-10559-5  0.6
2019 Ceanga M, Keiner S, Grünewald B, Haselmann H, Frahm C, Couillard-Després S, Witte OW, Redecker C, Geis C, Kunze A. Stroke accelerates and uncouples intrinsic and synaptic excitability maturation of mouse hippocampal DCX+ adult-born granule cells. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 30617211 DOI: 10.1523/Jneurosci.3303-17.2018  0.6
2018 Aramillo Irizar P, Schäuble S, Esser D, Groth M, Frahm C, Priebe S, Baumgart M, Hartmann N, Marthandan S, Menzel U, Müller J, Schmidt S, Ast V, Caliebe A, König R, et al. Transcriptomic alterations during ageing reflect the shift from cancer to degenerative diseases in the elderly. Nature Communications. 9: 327. PMID 29382830 DOI: 10.1038/S41467-017-02395-2  0.6
2017 Tadić V, Malci A, Goldhammer N, Stubendorff B, Sengupta S, Prell T, Keiner S, Liu J, Guenther M, Frahm C, Witte OW, Grosskreutz J. Sigma 1 receptor activation modifies intracellular calcium exchange in the G93A(hSOD1) ALS model. Neuroscience. PMID 28723387 DOI: 10.1016/j.neuroscience.2017.07.012  0.6
2016 Frahm C, Srivastava A, Schmidt S, Mueller J, Groth M, Guenther M, Ji Y, Priebe S, Platzer M, Witte OW. Transcriptional profiling reveals protective mechanisms in brains of long-lived mice. Neurobiology of Aging. 52: 23-31. PMID 28110102 DOI: 10.1016/j.neurobiolaging.2016.12.016  0.6
2016 Jaenisch N, Liebmann L, Guenther M, Hübner CA, Frahm C, Witte OW. Reduced tonic inhibition after stroke promotes motor performance and epileptic seizures. Scientific Reports. 6: 26173. PMID 27188341 DOI: 10.1038/srep26173  0.6
2015 Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, et al. Branched-chain amino acid catabolism is a conserved regulator of physiological ageing. Nature Communications. 6: 10043. PMID 26620638 DOI: 10.1038/ncomms10043  0.6
2015 Jahic A, Khundadze M, Jaenisch N, Schüle R, Klimpe S, Klebe S, Frahm C, Kassubek J, Stevanin G, Schöls L, Brice A, Hübner CA, Beetz C. The spectrum of KIAA0196 variants, and characterization of a murine knockout: implications for the mutational mechanism in hereditary spastic paraplegia type SPG8. Orphanet Journal of Rare Diseases. 10: 147. PMID 26572744 DOI: 10.1186/s13023-015-0359-x  0.6
2015 Schmidt C, Frahm C, Schneble N, Müller JP, Brodhun M, Franco I, Witte OW, Hirsch E, Wetzker R, Bauer R. Phosphoinositide 3-Kinase γ Restrains Neurotoxic Effects of Microglia After Focal Brain Ischemia. Molecular Neurobiology. PMID 26452362 DOI: 10.1007/s12035-015-9472-z  0.6
2014 Jaenisch N, Popp A, Guenther M, Schnabel J, Witte OW, Frahm C. Pro-apoptotic function of GABA-related transcripts following stroke. Neurobiology of Disease. 70: 237-44. PMID 24983209 DOI: 10.1016/j.nbd.2014.06.015  0.6
2014 Boehme M, Guenther M, Stahr A, Liebmann M, Jaenisch N, Witte OW, Frahm C. Impact of indomethacin on neuroinflammation and hippocampal neurogenesis in aged mice. Neuroscience Letters. 572: 7-12. PMID 24796813 DOI: 10.1016/j.neulet.2014.04.043  0.6
2014 Sieber MW, Guenther M, Jaenisch N, Albrecht-Eckardt D, Kohl M, Witte OW, Frahm C. Age-specific transcriptional response to stroke. Neurobiology of Aging. 35: 1744-54. PMID 24529500 DOI: 10.1016/j.neurobiolaging.2014.01.012  0.6
2013 Liebmann M, Stahr A, Guenther M, Witte OW, Frahm C. Astrocytic Cx43 and Cx30 differentially modulate adult neurogenesis in mice. Neuroscience Letters. 545: 40-5. PMID 23618652 DOI: 10.1016/j.neulet.2013.04.013  0.6
2013 Sieber MW, Jaenisch N, Brehm M, Guenther M, Linnartz-Gerlach B, Neumann H, Witte OW, Frahm C. Attenuated inflammatory response in triggering receptor expressed on myeloid cells 2 (TREM2) knock-out mice following stroke. Plos One. 8: e52982. PMID 23301011 DOI: 10.1371/journal.pone.0052982  0.6
2012 Stahr A, Frahm C, Kretz A, Bondeva T, Witte OW, Wolf G. Morg1(+/-) heterozygous mice are protected from experimentally induced focal cerebral ischemia. Brain Research. 1482: 22-31. PMID 22982595 DOI: 10.1016/j.brainres.2012.09.017  0.6
2012 Schmidt S, Bruehl C, Frahm C, Redecker C, Witte OW. Age dependence of excitatory-inhibitory balance following stroke. Neurobiology of Aging. 33: 1356-63. PMID 21257232 DOI: 10.1016/j.neurobiolaging.2010.11.019  0.6
2011 Sieber MW, Claus RA, Witte OW, Frahm C. Attenuated inflammatory response in aged mice brains following stroke. Plos One. 6: e26288. PMID 22028848 DOI: 10.1371/journal.pone.0026288  0.6
2010 Sieber MW, Recknagel P, Glaser F, Witte OW, Bauer M, Claus RA, Frahm C. Substantial performance discrepancies among commercially available kits for reverse transcription quantitative polymerase chain reaction: a systematic comparative investigator-driven approach. Analytical Biochemistry. 401: 303-11. PMID 20226159 DOI: 10.1016/j.ab.2010.03.007  0.6
2010 Jaenisch N, Witte OW, Frahm C. Downregulation of potassium chloride cotransporter KCC2 after transient focal cerebral ischemia. Stroke; a Journal of Cerebral Circulation. 41: e151-9. PMID 20044519 DOI: 10.1161/STROKEAHA.109.570424  0.6
2010 Sieber MW, Guenther M, Kohl M, Witte OW, Claus RA, Frahm C. Inter-age variability of bona fide unvaried transcripts Normalization of quantitative PCR data in ischemic stroke. Neurobiology of Aging. 31: 654-64. PMID 18606480 DOI: 10.1016/j.neurobiolaging.2008.05.023  0.6
2009 Popp A, Jaenisch N, Witte OW, Frahm C. Identification of ischemic regions in a rat model of stroke. Plos One. 4: e4764. PMID 19274095 DOI: 10.1371/journal.pone.0004764  0.6
2009 Popp A, Urbach A, Witte OW, Frahm C. Adult and embryonic GAD transcripts are spatiotemporally regulated during postnatal development in the rat brain. Plos One. 4: e4371. PMID 19190758 DOI: 10.1371/journal.pone.0004371  0.6
2008 Knopp A, Frahm C, Fidzinski P, Witte OW, Behr J. Loss of GABAergic neurons in the subiculum and its functional implications in temporal lobe epilepsy. Brain : a Journal of Neurology. 131: 1516-27. PMID 18504292 DOI: 10.1093/brain/awn095  0.6
2007 Haupt C, Witte OW, Frahm C. Up-regulation of Connexin43 in the glial scar following photothrombotic ischemic injury. Molecular and Cellular Neurosciences. 35: 89-99. PMID 17350281 DOI: 10.1016/j.mcn.2007.02.005  0.6
2007 Tolner EA, Frahm C, Metzger R, Gorter JA, Witte OW, Lopes da Silva FH, Heinemann U. Synaptic responses in superficial layers of medial entorhinal cortex from rats with kainate-induced epilepsy. Neurobiology of Disease. 26: 419-38. PMID 17350275 DOI: 10.1016/j.nbd.2007.01.009  0.6
2007 Haupt C, Witte OW, Frahm C. Temporal profile of connexin 43 expression after photothrombotic lesion in rat brain. Neuroscience. 144: 562-70. PMID 17112677 DOI: 10.1016/j.neuroscience.2006.09.054  0.6
2006 Haupt C, Tolner EA, Heinemann U, Witte OW, Frahm C. The combined use of non-radioactive in situ hybridization and real-time RT-PCR to assess gene expression in cryosections. Brain Research. 1118: 232-8. PMID 16996035 DOI: 10.1016/j.brainres.2006.08.037  0.6
2006 Frahm C, Siegel G, Grass S, Witte OW. Stable expression of the vesicular GABA transporter following photothrombotic infarct in rat brain. Neuroscience. 140: 865-77. PMID 16616431 DOI: 10.1016/j.neuroscience.2006.02.045  0.6
2004 Frahm C, Haupt C, Weinandy F, Siegel G, Bruehl C, Witte OW. Regulation of GABA transporter mRNA and protein after photothrombotic infarct in rat brain. The Journal of Comparative Neurology. 478: 176-88. PMID 15349978 DOI: 10.1002/cne.20282  0.6
2004 Hartmann K, Stief F, Draguhn A, Frahm C. Ionotropic GABA receptors with mixed pharmacological properties of GABAA and GABAC receptors. European Journal of Pharmacology. 497: 139-46. PMID 15306198 DOI: 10.1016/J.Ejphar.2004.06.044  0.6
2004 Frahm C, Haupt C, Witte OW. GABA neurons survive focal ischemic injury. Neuroscience. 127: 341-6. PMID 15262324 DOI: 10.1016/j.neuroscience.2004.05.027  0.6
2003 Frahm C, Stief F, Zuschratter W, Draguhn A. Unaltered control of extracellular GABA-concentration through GAT-1 in the hippocampus of rats after pilocarpine-induced status epilepticus. Epilepsy Research. 52: 243-52. PMID 12536057 DOI: 10.1016/S0920-1211(02)00233-4  0.6
2001 Frahm C, Draguhn A. GAD and GABA transporter (GAT-1) mRNA expression in the developing rat hippocampus. Brain Research. Developmental Brain Research. 132: 1-13. PMID 11744102 DOI: 10.1016/S0165-3806(01)00288-7  0.6
2001 Engel D, Pahner I, Schulze K, Frahm C, Jarry H, Ahnert-Hilger G, Draguhn A. Plasticity of rat central inhibitory synapses through GABA metabolism. The Journal of Physiology. 535: 473-82. PMID 11533137 DOI: 10.1111/J.1469-7793.2001.00473.X  0.6
2001 Frahm C, Engel D, Draguhn A. Efficacy of background GABA uptake in rat hippocampal slices. Neuroreport. 12: 1593-6. PMID 11409722 DOI: 10.1097/00001756-200106130-00016  0.6
2000 Frahm C, Engel D, Piechotta A, Heinemann U, Draguhn A. Presence of gamma-aminobutyric acid transporter mRNA in interneurons and principal cells of rat hippocampus. Neuroscience Letters. 288: 175-8. PMID 10889336 DOI: 10.1016/S0304-3940(00)01217-9  0.6
2000 Engel D, Endermann U, Frahm C, Heinemann U, Draguhn A. Acute effects of gamma-vinyl-GABA on low-magnesium evoked epileptiform activity in vitro. Epilepsy Research. 40: 99-107. PMID 10863137 DOI: 10.1016/S0920-1211(00)00112-1  0.6
1999 Sabau A, Frahm C, Pfeiffer M, Breustedt J, Piechotta A, Numberger M, Engel D, Heinemann U, Draguhn A. Age-dependence of the anticonvulsant effects of the GABA uptake inhibitor tiagabine in vitro. European Journal of Pharmacology. 383: 259-66. PMID 10594317 DOI: 10.1016/S0014-2999(99)00628-7  0.6
1998 Engel D, Schmitz D, Gloveli T, Frahm C, Heinemann U, Draguhn A. Laminar difference in GABA uptake and GAT-1 expression in rat CA1. The Journal of Physiology. 512: 643-9. PMID 9769410 DOI: 10.1111/J.1469-7793.1998.643Bd.X  0.6
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