Kevin Nicholas Hascup - Publications

Affiliations: 
Karolinska Institute, Stockholm, Sweden 
Area:
Glutamate Neurotransmission, Neurobiology, Behavioral Pharmacology

55 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Fang Y, Peck MR, Quinn K, Chapman JE, Medina D, McFadden SA, Bartke A, Hascup ER, Hascup KN. Senolytic intervention improves cognition, metabolism, and adiposity in female APP mice. Geroscience. PMID 39120687 DOI: 10.1007/s11357-024-01308-8  0.793
2024 Ikiz ED, Hascup ER, Bae C, Hascup KN. Microglial Piezo1 mechanosensitive channel as a therapeutic target in Alzheimer's disease. Frontiers in Cellular Neuroscience. 18: 1423410. PMID 38957539 DOI: 10.3389/fncel.2024.1423410  0.767
2024 McFadden SA, Peck MR, Sime LN, Cox MF, Ikiz ED, Findley CA, Quinn K, Fang Y, Bartke A, Hascup ER, Hascup KN. Thermotherapy has Sexually Dimorphic Responses in APP/PS1 Mice. Biorxiv : the Preprint Server For Biology. PMID 38586039 DOI: 10.1101/2024.03.26.586836  0.795
2023 Fang Y, Peck MR, Quinn K, Medina D, Roy S, McFadden SA, Bartke A, Hascup KN, Hascup ER. Senolytic Intervention Improves Cognition, Metabolism, and Adiposity in Female APP Mice. Biorxiv : the Preprint Server For Biology. PMID 38168356 DOI: 10.1101/2023.12.12.571277  0.79
2023 Britz J, Ojo E, Haque N, Dhukhwa A, Hascup ER, Hascup KN, Tischkau SA. Sex-Dependent Effects of Chronic Circadian Disruption in AβPP/PS1 Mice. Journal of Alzheimer's Disease : Jad. PMID 38143343 DOI: 10.3233/JAD-230089  0.754
2023 Findley CA, McFadden SA, Hill T, Peck MR, Quinn K, Hascup KN, Hascup ER. Altered Hippocampal Glutamatergic Neurotransmission and Cognitive Impairment in APP Knock-In Mice. Biorxiv : the Preprint Server For Biology. PMID 38106074 DOI: 10.1101/2023.12.05.570100  0.807
2023 Yuan R, Hascup E, Hascup K, Bartke A. Relationships among Development, Growth, Body Size, Reproduction, Aging, and Longevity - Trade-Offs and Pace-Of-Life. Biochemistry. Biokhimiia. 88: 1692-1703. PMID 38105191 DOI: 10.1134/S0006297923110020  0.744
2023 McDaniel JT, Hascup KN, Hascup ER, Ezigbo UG, Weidhuner AM, Henson H, Albright DL. Cognitive function among military veterans with STEM occupations. Military Medical Research. 10: 55. PMID 37986137 DOI: 10.1186/s40779-023-00491-7  0.742
2023 Fang Y, Medina D, Stockwell R, McFadden S, Quinn K, Peck MR, Bartke A, Hascup KN, Hascup ER. Sexual dimorphic metabolic and cognitive responses of C57BL/6 mice to Fisetin or Dasatinib and quercetin cocktail oral treatment. Geroscience. PMID 37296266 DOI: 10.1007/s11357-023-00843-0  0.778
2023 Findley CA, McFadden SA, Cox MF, Sime LN, Peck MR, Quinn K, Bartke A, Hascup KN, Hascup ER. Prodromal Glutamatergic Modulation with Riluzole Impacts Glucose Homeostasis and Spatial Cognition in Alzheimer's Disease Mice. Journal of Alzheimer's Disease : Jad. PMID 37248899 DOI: 10.3233/JAD-221245  0.786
2023 Bartke A, Hascup E, Hascup K. Responses to Many Anti-Aging Interventions Are Sexually Dimorphic. The World Journal of Men's Health. PMID 37118966 DOI: 10.5534/wjmh.230015  0.76
2023 Findley CA, Cox MF, Lipson AB, Bradley R, Hascup KN, Yuede C, Hascup ER. Health disparities in aging: Improving dementia care for Black women. Frontiers in Aging Neuroscience. 15: 1107372. PMID 36845663 DOI: 10.3389/fnagi.2023.1107372  0.745
2022 Fang Y, Medina D, Stockwell R, McFadden S, Hascup ER, Hascup KN, Bartke A. Resistance to mild cold stress is greater in both wild-type and long-lived GHR-KO female mice. Geroscience. 45: 1081-1093. PMID 36527583 DOI: 10.1007/s11357-022-00706-0  0.772
2022 McFadden S, Sime LN, Cox MKF, Findley CA, Peck MR, Quinn K, Fang Y, Bartke A, Hascup ER, Hascup KN. Chronic, Mild Hypothermic Environmental Temperature does not Ameliorate Cognitive Deficits in an Alzheimer's Disease Mouse. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 36398842 DOI: 10.1093/gerona/glac223  0.792
2022 Cox MF, Hascup ER, Bartke A, Hascup KN. Friend or Foe? Defining the Role of Glutamate in Aging and Alzheimer's Disease. Frontiers in Aging. 3: 929474. PMID 35821835 DOI: 10.3389/fragi.2022.929474  0.79
2022 McDaniel JT, Hascup ER, Hascup KN, Trivedi M, Henson H, Rados R, York M, Albright DL, Weatherly T, Frick K. Psychological Resilience and Cognitive Function Among Older Military Veterans. Gerontology & Geriatric Medicine. 8: 23337214221081363. PMID 35252475 DOI: 10.1177/23337214221081363  0.75
2022 Hascup ER, Sime LN, Peck MR, Hascup KN. Amyloid-β stimulated hippocampal lactate release is coupled to glutamate uptake. Scientific Reports. 12: 2775. PMID 35177691 DOI: 10.1038/s41598-022-06637-2  0.801
2021 Britz J, Ojo E, Dhukhwa A, Saito T, Saido TC, Hascup ER, Hascup KN, Tischkau SA. Assessing Sex-Specific Circadian, Metabolic, and Cognitive Phenotypes in the AβPP/PS1 and APPNL - F/NL - F Models of Alzheimer's Disease. Journal of Alzheimer's Disease : Jad. PMID 34897085 DOI: 10.3233/JAD-210629  0.763
2021 Schneider A, Victoria B, Schiavon Cousen MI, Fang Y, McFadden S, Darcy J, Gesing A, Hascup ER, Hascup KN, Bartke A, Masternak MM. Growth hormone signaling shapes the impact of environmental temperature on transcriptomic profile of different adipose tissue depots in male mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 34614153 DOI: 10.1093/gerona/glab291  0.769
2021 Bartke A, Hascup E, Hascup K, Masternak MM. Growth Hormone and Aging: New Findings. The World Journal of Men's Health. PMID 33663025 DOI: 10.5534/wjmh.200201  0.763
2020 Bartke A, Brannan S, Hascup E, Hascup K, Darcy J. Energy Metabolism and Aging. The World Journal of Men's Health. PMID 33151044 DOI: 10.5534/Wjmh.200112  0.76
2020 Hascup KN, Findley CA, Britz J, Esperant-Hilaire N, Broderick SO, Delfino K, Tischkau S, Bartke A, Hascup ER. Riluzole Attenuates Glutamatergic Tone and Cognitive Decline in AβPP/PS1 Mice. Journal of Neurochemistry. PMID 33107040 DOI: 10.1111/jnc.15224  0.808
2020 Hascup ER, Hascup KN. Toward refining Alzheimer's disease into overlapping subgroups. Alzheimer's & Dementia (New York, N. Y.). 6: e12070. PMID 32885025 DOI: 10.1002/trc2.12070  0.775
2020 Hascup KN, Findley CA, Sime LN, Hascup ER. Hippocampal alterations in glutamatergic signaling during amyloid progression in AβPP/PS1 mice. Scientific Reports. 10: 14503. PMID 32879385 DOI: 10.1038/s41598-020-71587-6  0.81
2020 Solis E, Hascup KN, Hascup ER. Alzheimer's Disease: The Link Between Amyloid-β and Neurovascular Dysfunction. Journal of Alzheimer's Disease : Jad. PMID 32597813 DOI: 10.3233/JAD-200473  0.773
2020 Hascup ER, Hascup KN. Does SARS-CoV-2 infection cause chronic neurological complications? Geroscience. PMID 32451846 DOI: 10.1007/s11357-020-00207-y  0.746
2020 Fang Y, McFadden S, Darcy J, Hascup ER, Hascup KN, Bartke A. Lifespan of long-lived growth hormone receptor knockout mice was not normalized by housing at 30°C since weaning. Aging Cell. e13123. PMID 32110850 DOI: 10.1111/Acel.13123  0.784
2019 Findley CA, Bartke A, Hascup KN, Hascup ER. Amyloid Beta-Related Alterations to Glutamate Signaling Dynamics During Alzheimer's Disease Progression. Asn Neuro. 11: 1759091419855541. PMID 31213067 DOI: 10.1177/1759091419855541  0.779
2019 Hascup KN, Britz J, Findley CA, Tischkau S, Hascup ER. LY379268 Does Not Have Long-Term Procognitive Effects nor Attenuate Glutamatergic Signaling in AβPP/PS1 Mice. Journal of Alzheimer's Disease : Jad. PMID 30909243 DOI: 10.3233/Jad-181231  0.819
2018 Hascup ER, Broderick SO, Russell MK, Fang Y, Bartke A, Boger HA, Hascup KN. Diet-Induced Insulin Resistance Elevates Hippocampal Glutamate as well as VGLUT1 and GFAP Expression in AβPP/PS1 Mice. Journal of Neurochemistry. PMID 30472734 DOI: 10.1111/Jnc.14634  0.81
2016 Hascup KN, Lynn MK, Fitzgerald PJ, Randall S, Kopchick JJ, Boger HA, Bartke A, Hascup ER. Enhanced Cognition and Hypoglutamatergic Signaling in a Growth Hormone Receptor Knockout Mouse Model of Successful Aging. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 27208894 DOI: 10.1093/Gerona/Glw088  0.806
2016 Hascup KN, Hascup ER. Soluble Amyloid-β42 Stimulates Glutamate Release through Activation of the α7 Nicotinic Acetylcholine Receptor. Journal of Alzheimer's Disease : Jad. PMID 27163813 DOI: 10.3233/JAD-160041  0.801
2016 Hascup KN, Broderick SO, Hascup ER. O4-03-06: Diet-Induced Obesity Causes Glutamatergic Dysregulation and Exacerbates Memory Impairment in ABPP/PS1 Mice Alzheimer's & Dementia. 12: P339-P339. DOI: 10.1016/J.Jalz.2016.06.623  0.769
2016 Hascup KN, Broderick SO, Hascup ER. P4-008: Can Alzheimer’S-Related Cognitive Decline be Delayed Through Prodromal Treatment? Evidence from a Mouse Model of Alzheimer’s Disease Alzheimer's & Dementia. 12: P1017-P1017. DOI: 10.1016/J.Jalz.2016.06.2097  0.772
2015 Hascup KN, Hascup ER. Altered neurotransmission prior to cognitive decline in AβPP/PS1 mice, a model of Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 44: 771-6. PMID 25374106 DOI: 10.3233/JAD-142160  0.813
2015 Hascup KN, Broderick SO, Hascup ER. O2-12-01: Soluble amyloid-β42 activates α7nAChR in vivo and alters glutamatergic neurotransmission prior to cognitive decline in Aβpp/ps1 mice Alzheimer's & Dementia. 11: P202-P202. DOI: 10.1016/J.Jalz.2015.07.195  0.785
2014 Hascup KN, Hascup ER. Electrochemical techniques for subsecond neurotransmitter detection in live rodents. Comparative Medicine. 64: 249-55. PMID 25296011  0.768
2013 Eriksson TM, Alvarsson A, Stan TL, Zhang X, Hascup KN, Hascup ER, Kehr J, Gerhardt GA, Warner-Schmidt J, Arango-Lievano M, Kaplitt MG, Ogren SO, Greengard P, Svenningsson P. Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11. Molecular Psychiatry. 18: 1096-105. PMID 23032875 DOI: 10.1038/Mp.2012.130  0.776
2013 Hascup ER, Hascup KN, Talauliker PM, Price DA, Pomerleau F, Quintero JE, Huettl P, Gratton A, Strömberg I, Gerhardt GA. Sub-second measurements of glutamate and other neurotransmitter signaling using enzyme-based ceramic microelectrode arrays Neuromethods. 80: 179-199. DOI: 10.1007/978-1-62703-370-1-8  0.749
2013 Hascup KN, Hascup ER, Littrell OM, Hinzman JM, Werner CE, Davis VA, Burmeister JJ, Pomerleau F, Quintero JE, Huettl P, Gerhardt GA. Microelectrode array fabrication and optimization for selective neurochemical detection Neuromethods. 80: 27-54. DOI: 10.1007/978-1-62703-370-1-2  0.713
2012 Hascup ER, Hascup KN, Pomerleau F, Huettl P, Hajos-Korcsok E, Kehr J, Gerhardt GA. An allosteric modulator of metabotropic glutamate receptors (mGluRâ‚‚), (+)-TFMPIP, inhibits restraint stress-induced phasic glutamate release in rat prefrontal cortex. Journal of Neurochemistry. 122: 619-27. PMID 22578190 DOI: 10.1111/j.1471-4159.2012.07784.x  0.785
2011 Hascup KN, Hascup ER, Stephens ML, Glaser PE, Yoshitake T, Mathé AA, Gerhardt GA, Kehr J. Resting glutamate levels and rapid glutamate transients in the prefrontal cortex of the Flinders Sensitive Line rat: a genetic rodent model of depression. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology. 36: 1769-77. PMID 21525860 DOI: 10.1038/Npp.2011.60  0.775
2011 Hascup KN, Bao X, Hascup ER, Hui D, Xu W, Pomerleau F, Huettl P, Michaelis ML, Michaelis EK, Gerhardt GA. Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum. Asn Neuro. 3. PMID 21446915 DOI: 10.1042/An20110005  0.803
2011 Michaelis EK, Wang X, Pal R, Bao X, Hascup KN, Wang Y, Wang WT, Hui D, Agbas A, Choi IY, Belousov A, Gerhardt GA. Neuronal Glud1 (glutamate dehydrogenase 1) over-expressing mice: increased glutamate formation and synaptic release, loss of synaptic activity, and adaptive changes in genomic expression. Neurochemistry International. 59: 473-81. PMID 21397652 DOI: 10.1016/J.Neuint.2011.03.003  0.704
2011 Alvarsson A, Eriksson T, Stan T, Hascup K, Hascup E, Gerhardt G, Svenningsson P. P.1.c.041 The effects of 5-HT1B receptor modulation on glutamatergic neurotransmission in vivo European Neuropsychopharmacology. 21: S276-S277. DOI: 10.1016/S0924-977X(11)70432-1  0.753
2010 Hascup ER, Hascup KN, Stephens M, Pomerleau F, Huettl P, Gratton A, Gerhardt GA. Rapid microelectrode measurements and the origin and regulation of extracellular glutamate in rat prefrontal cortex. Journal of Neurochemistry. 115: 1608-20. PMID 20969570 DOI: 10.1111/J.1471-4159.2010.07066.X  0.784
2009 Bao X, Pal R, Hascup KN, Wang Y, Wang WT, Xu W, Hui D, Agbas A, Wang X, Michaelis ML, Choi IY, Belousov AB, Gerhardt GA, Michaelis EK. Transgenic expression of Glud1 (glutamate dehydrogenase 1) in neurons: in vivo model of enhanced glutamate release, altered synaptic plasticity, and selective neuronal vulnerability. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 29: 13929-44. PMID 19890003 DOI: 10.1523/Jneurosci.4413-09.2009  0.689
2009 Hascup ER, af Bjerkén S, Hascup KN, Pomerleau F, Huettl P, Strömberg I, Gerhardt GA. Histological studies of the effects of chronic implantation of ceramic-based microelectrode arrays and microdialysis probes in rat prefrontal cortex. Brain Research. 1291: 12-20. PMID 19577548 DOI: 10.1016/j.brainres.2009.06.084  0.771
2009 Hascup K, Hascup E, Gerhardt G, Mathé A, Kehr J. P.2.10 Neuropeptide Y modulation of the gluta-matergic system in the Flinders Sensitive Line rat: a rat model of depression European Neuropsychopharmacology. 19: S41-S42. DOI: 10.1016/S0924-977X(09)70048-3  0.78
2009 Hascup E, Hascup K, Pomerleau F, Huettl P, Gerhardt G, Kehr J. P.2.09 The source of resting and physiologically-evoked L-glutamate levels in prefrontal cortex in awake rats European Neuropsychopharmacology. 19: S40-S41. DOI: 10.1016/S0924-977X(09)70047-1  0.765
2008 Hascup KN, Hascup ER, Pomerleau F, Huettl P, Gerhardt GA. Second-by-second measures of L-glutamate in the prefrontal cortex and striatum of freely moving mice. The Journal of Pharmacology and Experimental Therapeutics. 324: 725-31. PMID 18024788 DOI: 10.1124/jpet.107.131698  0.806
2008 Michaelis EK, Bao X, Pal R, Hascup K, McKerchar T, Xu W, Hui D, Agbas A, Wang X, Pinkston J, Pomerleau F, Huettl P, Fowler S, Michaelis M, Gerhardt G. P4-259: Transgenic expression of glutamate gehydrogenase 1 in neurons: An in vivo model of hyperglutamatergic nervous system and chronic neurodegeneration Alzheimer's & Dementia. 4: T747-T747. DOI: 10.1016/J.Jalz.2008.05.2328  0.668
2008 Stephens ML, Spencer DD, Cavus I, Hsiao MC, Song D, Deadwyler SA, Hampson RE, Putz D, Quintero JE, Bensalem-Owen MK, Hascup KN, Rutherford EC, Day BK, Nickell JR, Pomerleau F, et al. Microelectrode-Based Epilepsy Therapy: A Hybrid Neural Prosthesis Incorporating Seizure Prediction and Intervention with Biomimetic Maintenance of Normal Hippocampal Function Computational Neuroscience in Epilepsy. 559-586. DOI: 10.1016/B978-012373649-9.50036-3  0.723
2006 Hascup KN, Broderick SO, Russell MK, Boger HA, Hascup ER. P2-160: DIETARY INSULIN RESISTANCE IMPAIRS COGNITION AND ELEVATES HIPPOCAMPAL GLUTAMATE DYNAMICS IN AβPP/PS1 MICE Alzheimer's & Dementia. 14: P729-P730. DOI: 10.1016/J.Jalz.2018.06.847  0.79
2006 Hascup KN, Broderick SO, Britz J, Hascup ER. P2-062: RILUZOLE AS AN EARLY THERAPEUTIC AGENT FOR ALZHEIMER'S DISEASE Alzheimer's & Dementia. 14: P690-P690. DOI: 10.1016/J.Jalz.2018.06.747  0.761
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