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David S. Gokhin, Ph.D. - Publications

Affiliations: 
2009 Bioengineering University of California, San Diego, La Jolla, CA 
Area:
Biomedical, Biomechanics
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31 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Smith AS, Nowak RB, Zhou S, Giannetto M, Gokhin DS, Papoin J, Ghiran IC, Blanc L, Wan J, Fowler VM. Myosin IIA interacts with the spectrin-actin membrane skeleton to control red blood cell membrane curvature and deformability. Proceedings of the National Academy of Sciences of the United States of America. PMID 29610350 DOI: 10.1073/Pnas.1718285115  0.43
2017 Nowak RB, Papoin J, Gokhin DS, Casu C, Rivella S, Lipton JM, Blanc L, Fowler VM. Tropomodulin1 Controls Erythroblast Enucleation via Regulation of F-Actin in the Enucleosome. Blood. PMID 28729432 DOI: 10.1182/Blood-2017-05-787051  0.412
2017 Sui Z, Gokhin DS, Nowak RB, Guo X, An X, Fowler VM. Stabilization of F-actin by tropomyosin isoforms regulates the morphology and mechanical behavior of red blood cells. Molecular Biology of the Cell. PMID 28720661 DOI: 10.1091/Mbc.E16-10-0699  0.431
2016 Gokhin DS, Fowler VM. Software-based measurement of thin filament lengths: an open-source GUI for Distributed Deconvolution analysis of fluorescence images. Journal of Microscopy. PMID 27644080 DOI: 10.1111/Jmi.12456  0.408
2016 Cheng C, Gokhin DS, Nowak RB, Fowler VM. Sequential Application of Glass Coverslips to Assess the Compressive Stiffness of the Mouse Lens: Strain and Morphometric Analyses. Journal of Visualized Experiments : Jove. PMID 27166880 DOI: 10.3791/53986  0.328
2016 Gokhin DS, Fowler VM. Feisty filaments: actin dynamics in the red blood cell membrane skeleton. Current Opinion in Hematology. 23: 206-214. PMID 27055045 DOI: 10.1097/Moh.0000000000000227  0.453
2015 Gokhin DS, Ochala J, Domenighetti AA, Fowler VM. Tropomodulin 1 directly controls thin filament length in both wild-type and tropomodulin 4-deficient skeletal muscle. Development (Cambridge, England). 142: 4351-62. PMID 26586224 DOI: 10.1242/Jcs.184986  0.548
2015 Gokhin DS, Nowak RB, Khoory JA, Piedra Ade L, Ghiran IC, Fowler VM. Dynamic actin filaments control the mechanical behavior of the human red blood cell membrane. Molecular Biology of the Cell. 26: 1699-710. PMID 25717184 DOI: 10.1091/Mbc.E14-12-1583  0.442
2015 Yuen M, Sandaradura SA, Dowling JJ, Kostyukova AS, Moroz N, Quinlan KG, Lehtokari VL, Ravenscroft G, Todd EJ, Ceyhan-Birsoy O, Gokhin DS, Maluenda J, Lek M, Nolent F, Pappas CT, et al. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy. The Journal of Clinical Investigation. 125: 456-7. PMID 25654555 DOI: 10.1172/Jci80057  0.48
2014 Gokhin DS, Dubuc EA, Lian KQ, Peters LL, Fowler VM. Alterations in thin filament length during postnatal skeletal muscle development and aging in mice. Frontiers in Physiology. 5: 375. PMID 25324783 DOI: 10.3389/Fphys.2014.00375  0.543
2014 Yuen M, Sandaradura SA, Dowling JJ, Kostyukova AS, Moroz N, Quinlan KG, Lehtokari VL, Ravenscroft G, Todd EJ, Ceyhan-Birsoy O, Gokhin DS, Maluenda J, Lek M, Nolent F, Pappas CT, et al. Leiomodin-3 dysfunction results in thin filament disorganization and nemaline myopathy. The Journal of Clinical Investigation. 124: 4693-708. PMID 25250574 DOI: 10.1172/Jci75199  0.528
2014 Lewis RA, Yamashiro S, Gokhin DS, Fowler VM. Functional effects of mutations in the tropomyosin-binding sites of tropomodulin1 and tropomodulin3. Cytoskeleton (Hoboken, N.J.). 71: 395-411. PMID 24922351 DOI: 10.1002/Cm.21179  0.355
2014 Yamashiro S, Gokhin DS, Sui Z, Bergeron SE, Rubenstein PA, Fowler VM. Differential actin-regulatory activities of Tropomodulin1 and Tropomodulin3 with diverse tropomyosin and actin isoforms. The Journal of Biological Chemistry. 289: 11616-29. PMID 24644292 DOI: 10.1074/Jbc.M114.555128  0.522
2014 McKeown CR, Nowak RB, Gokhin DS, Fowler VM. Tropomyosin is required for cardiac morphogenesis, myofibril assembly, and formation of adherens junctions in the developing mouse embryo. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 243: 800-17. PMID 24500875 DOI: 10.1002/Dvdy.24115  0.402
2014 Gokhin DS, Tierney MT, Sui Z, Sacco A, Fowler VM. Calpain-mediated proteolysis of tropomodulin isoforms leads to thin filament elongation in dystrophic skeletal muscle. Molecular Biology of the Cell. 25: 852-65. PMID 24430868 DOI: 10.1091/Mbc.E13-10-0608  0.54
2014 Ochala J, Gokhin DS, Iwamoto H, Fowler VM. Pointed-end capping by tropomodulin modulates actomyosin crossbridge formation in skeletal muscle fibers. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 28: 408-15. PMID 24072783 DOI: 10.1096/Fj.13-239640  0.518
2014 Domenighetti AA, Chu PH, Wu T, Sheikh F, Gokhin DS, Guo LT, Cui Z, Peter AK, Christodoulou DC, Parfenov MG, Gorham JM, Li DY, Banerjee I, Lai X, Witzmann FA, et al. Loss of FHL1 induces an age-dependent skeletal muscle myopathy associated with myofibrillar and intermyofibrillar disorganization in mice. Human Molecular Genetics. 23: 209-25. PMID 23975679 DOI: 10.1093/Hmg/Ddt412  0.479
2013 Yamamoto DL, Vitiello C, Zhang J, Gokhin DS, Castaldi A, Coulis G, Piaser F, Filomena MC, Eggenhuizen PJ, Kunderfranco P, Camerini S, Takano K, Endo T, Crescenzi M, Luther PK, et al. The nebulin SH3 domain is dispensable for normal skeletal muscle structure but is required for effective active load bearing in mouse. Journal of Cell Science. 126: 5477-89. PMID 24046450 DOI: 10.1242/Dev.106625  0.406
2013 Gokhin DS, Fowler VM. A two-segment model for thin filament architecture in skeletal muscle. Nature Reviews. Molecular Cell Biology. 14: 113-9. PMID 23299957 DOI: 10.1038/Nrm3510  0.519
2012 Gokhin DS, Nowak RB, Kim NE, Arnett EE, Chen AC, Sah RL, Clark JI, Fowler VM. Tmod1 and CP49 synergize to control the fiber cell geometry, transparency, and mechanical stiffness of the mouse lens. Plos One. 7: e48734. PMID 23144950 DOI: 10.1371/Journal.Pone.0048734  0.568
2012 Ochala J, Gokhin DS, Pénisson-Besnier I, Quijano-Roy S, Monnier N, Lunardi J, Romero NB, Fowler VM. Congenital myopathy-causing tropomyosin mutations induce thin filament dysfunction via distinct physiological mechanisms. Human Molecular Genetics. 21: 4473-85. PMID 22798622 DOI: 10.1093/Hmg/Dds289  0.431
2012 Yamashiro S, Gokhin DS, Kimura S, Nowak RB, Fowler VM. Tropomodulins: pointed-end capping proteins that regulate actin filament architecture in diverse cell types. Cytoskeleton (Hoboken, N.J.). 69: 337-70. PMID 22488942 DOI: 10.1002/Cm.21031  0.51
2012 Gokhin DS, Kim NE, Lewis SA, Hoenecke HR, D'Lima DD, Fowler VM. Thin-filament length correlates with fiber type in human skeletal muscle. American Journal of Physiology. Cell Physiology. 302: C555-65. PMID 22075691 DOI: 10.1152/Ajpcell.00299.2011  0.538
2011 Gokhin DS, Fowler VM. The sarcoplasmic reticulum: Actin and tropomodulin hit the links. Bioarchitecture. 1: 175-179. PMID 22069510 DOI: 10.4161/bioa.1.4.17533  0.438
2011 Gokhin DS, Fowler VM. Tropomodulin capping of actin filaments in striated muscle development and physiology. Journal of Biomedicine & Biotechnology. 2011: 103069. PMID 22013379 DOI: 10.1155/2011/103069  0.589
2011 Gokhin DS, Fowler VM. Cytoplasmic gamma-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers. The Journal of Cell Biology. 194: 105-20. PMID 21727195 DOI: 10.1083/Jcb.201011128  0.576
2011 Gokhin DS, Fowler VM. Cytoplasmic γ-actin and tropomodulin isoforms link to the sarcoplasmic reticulum in skeletal muscle fibers The Journal of General Physiology. 138. DOI: 10.1085/Jgp1382Oia1  0.533
2010 Gokhin DS, Lewis RA, McKeown CR, Nowak RB, Kim NE, Littlefield RS, Lieber RL, Fowler VM. Tropomodulin isoforms regulate thin filament pointed-end capping and skeletal muscle physiology. The Journal of Cell Biology. 189: 95-109. PMID 20368620 DOI: 10.1085/Jgp1355Oia4  0.545
2009 Gokhin DS, Bang ML, Zhang J, Chen J, Lieber RL. Reduced thin filament length in nebulin-knockout skeletal muscle alters isometric contractile properties. American Journal of Physiology. Cell Physiology. 296: C1123-32. PMID 19295172 DOI: 10.1152/Ajpcell.00503.2008  0.465
2008 Zhang J, Bang ML, Gokhin DS, Lu Y, Cui L, Li X, Gu Y, Dalton ND, Scimia MC, Peterson KL, Lieber RL, Chen J. Syncoilin is required for generating maximum isometric stress in skeletal muscle but dispensable for muscle cytoarchitecture. American Journal of Physiology. Cell Physiology. 294: C1175-82. PMID 18367591 DOI: 10.1152/Ajpcell.00049.2008  0.415
2008 Gokhin DS, Ward SR, Bremner SN, Lieber RL. Quantitative analysis of neonatal skeletal muscle functional improvement in the mouse. The Journal of Experimental Biology. 211: 837-43. PMID 18310108 DOI: 10.1242/Jeb.014340  0.392
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