David Ish-Horowicz - Publications

Affiliations: 
1977-2013 Developmental Genetics Cancer Research UK, Belfast, Northern Ireland, United Kingdom 
 2013- Cell and Developmeantal Biology University College London, London, United Kingdom 
Area:
segmentation, RNA localisation, post-transcriptional control of gene expression

76 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Prajapati RS, Mitter R, Vezzaro A, Ish-Horowicz D. is required for axial elongation and segmentation in vertebrate embryos. Biology Open. PMID 31988092 DOI: 10.1242/Bio.047290  0.461
2020 Samuels TJ, Järvelin AI, Ish-Horowicz D, Davis I. Imp/IGF2BP levels modulate individual neural stem cell growth and division through mRNA stability. Elife. 9. PMID 31934860 DOI: 10.7554/Elife.51529  0.342
2017 Yang CP, Samuels TJ, Huang Y, Yang L, Ish-Horowicz D, Davis I, Lee T. Imp and Syp RNA-binding proteins govern decommissioning of Drosophila neural stem cells. Development (Cambridge, England). PMID 28851709 DOI: 10.1242/Dev.149500  0.306
2017 Yang L, Titlow J, Ennis D, Smith C, Mitchell J, Young FL, Waddell S, Ish-Horowicz D, Davis I. Single molecule fluorescence in situ hybridisation for quantitating post-transcriptional regulation in Drosophila brains. Methods (San Diego, Calif.). PMID 28651965 DOI: 10.1016/J.Ymeth.2017.06.025  0.377
2014 Hayashi R, Handler D, Ish-Horowicz D, Brennecke J. The exon junction complex is required for definition and excision of neighboring introns in Drosophila. Genes & Development. 28: 1772-85. PMID 25081352 DOI: 10.1101/Gad.245738.114  0.366
2014 Terenzio M, Golding M, Russell MR, Wicher KB, Rosewell I, Spencer-Dene B, Ish-Horowicz D, Schiavo G. Bicaudal-D1 regulates the intracellular sorting and signalling of neurotrophin receptors. The Embo Journal. 33: 1582-98. PMID 24920579 DOI: 10.15252/Embj.201387579  0.324
2014 Soza-Ried C, Öztürk E, Ish-Horowicz D, Lewis J. Pulses of Notch activation synchronise oscillating somite cells and entrain the zebrafish segmentation clock. Development (Cambridge, England). 141: 1780-8. PMID 24715465 DOI: 10.1242/Dev.102111  0.66
2014 Hayashi R, Wainwright SM, Liddell SJ, Pinchin SM, Horswell S, Ish-Horowicz D. A genetic screen based on in vivo RNA imaging reveals centrosome-independent mechanisms for localizing gurken transcripts in Drosophila. G3 (Bethesda, Md.). 4: 749-60. PMID 24531791 DOI: 10.1534/G3.114.010462  0.367
2013 Hoyle NP, Ish-Horowicz D. Transcript processing and export kinetics are rate-limiting steps in expressing vertebrate segmentation clock genes. Proceedings of the National Academy of Sciences of the United States of America. 110: E4316-24. PMID 24151332 DOI: 10.1073/Pnas.1308811110  0.418
2012 Stauber M, Laclef C, Vezzaro A, Page ME, Ish-Horowicz D. Modifying transcript lengths of cycling mouse segmentation genes. Mechanisms of Development. 129: 61-72. PMID 22326607 DOI: 10.1016/J.Mod.2012.01.006  0.427
2011 Roffey JR, Hammonds T, Raynham T, Dillon C, Hyde C, Pearl L, Ish-Horowicz D. Abstract C126: Molecular profiling of the HES transcription factor-TLE co-repressor protein-protein interaction site. Molecular Cancer Therapeutics. 10. DOI: 10.1158/1535-7163.Targ-11-C126  0.365
2010 Rallis C, Pinchin SM, Ish-Horowicz D. Cell-autonomous integrin control of Wnt and Notch signalling during somitogenesis. Development (Cambridge, England). 137: 3591-601. PMID 20876653 DOI: 10.1242/Dev.050070  0.387
2010 Bullock SL, Ringel I, Ish-Horowicz D, Lukavsky PJ. A'-form RNA helices are required for cytoplasmic mRNA transport in Drosophila. Nature Structural & Molecular Biology. 17: 703-9. PMID 20473315 DOI: 10.1038/Nsmb.1813  0.677
2010 Vanrobays E, Jennings BH, Ish-Horowicz D. Identification and mapping of induced chromosomal deletions using sequence polymorphisms. Biotechniques. 48: 53-60. PMID 20078428 DOI: 10.2144/000113348  0.747
2009 Stauber M, Sachidanandan C, Morgenstern C, Ish-Horowicz D. Differential axial requirements for lunatic fringe and Hes7 transcription during mouse somitogenesis. Plos One. 4: e7996. PMID 19956724 DOI: 10.1371/Journal.Pone.0007996  0.459
2009 Jennings B, Harvey R, Ish-Horowicz D. 05-P006 Regulation of transcriptional elongation by spt5 during drosophila development Mechanisms of Development. 126: S114. DOI: 10.1016/J.Mod.2009.06.211  0.658
2008 Jennings BH, Ish-Horowicz D. The Groucho/TLE/Grg family of transcriptional co-repressors. Genome Biology. 9: 205. PMID 18254933 DOI: 10.1186/Gb-2008-9-1-205  0.683
2008 Jennings BH, Wainwright SM, Ish-Horowicz D. Differential in vivo requirements for oligomerization during Groucho-mediated repression. Embo Reports. 9: 76-83. PMID 18034187 DOI: 10.1038/Sj.Embor.7401122  0.67
2008 Molenaar C, Ish-Horowicz D. Dissecting RNA localisation pathways in neuroblasts and neurons in the Drosophila embryo Developmental Biology. 319: 577. DOI: 10.1016/J.Ydbio.2008.05.388  0.312
2006 Jennings BH, Pickles LM, Wainwright SM, Roe SM, Pearl LH, Ish-Horowicz D. Molecular recognition of transcriptional repressor motifs by the WD domain of the Groucho/TLE corepressor. Molecular Cell. 22: 645-55. PMID 16762837 DOI: 10.1016/J.Molcel.2006.04.024  0.653
2005 Kidd T, Abu-Shumays R, Katzen A, Sisson JC, Jiménez G, Pinchin S, Sullivan W, Ish-Horowicz D. The epsilon-subunit of mitochondrial ATP synthase is required for normal spindle orientation during the Drosophila embryonic divisions. Genetics. 170: 697-708. PMID 15834145 DOI: 10.1534/Genetics.104.037648  0.502
2004 Hughes JR, Bullock SL, Ish-Horowicz D. Inscuteable mRNA localization is dynein-dependent and regulates apicobasal polarity and spindle length in Drosophila neuroblasts. Current Biology : Cb. 14: 1950-6. PMID 15530398 DOI: 10.1016/J.Cub.2004.10.022  0.696
2004 Jennings BH, Shah S, Yamaguchi Y, Seki M, Phillips RG, Handa H, Ish-Horowicz D. Locus-specific requirements for Spt5 in transcriptional activation and repression in Drosophila. Current Biology : Cb. 14: 1680-4. PMID 15380072 DOI: 10.1016/J.Cub.2004.08.066  0.726
2004 Bullock SL, Stauber M, Prell A, Hughes JR, Ish-Horowicz D, Schmidt-Ott U. Differential cytoplasmic mRNA localisation adjusts pair-rule transcription factor activity to cytoarchitecture in dipteran evolution. Development (Cambridge, England). 131: 4251-61. PMID 15280214 DOI: 10.1242/Dev.01289  0.727
2004 Aerne B, Ish-Horowicz D. Receptor tyrosine phosphatase psi is required for Delta/Notch signalling and cyclic gene expression in the presomitic mesoderm. Development (Cambridge, England). 131: 3391-9. PMID 15226256 DOI: 10.1242/Dev.01222  0.469
2004 Hozumi K, Negishi N, Suzuki D, Abe N, Sotomaru Y, Tamaoki N, Mailhos C, Ish-Horowicz D, Habu S, Owen MJ. Delta-like 1 is necessary for the generation of marginal zone B cells but not T cells in vivo. Nature Immunology. 5: 638-44. PMID 15146182 DOI: 10.1038/Ni1075  0.337
2003 Aerne B, Stoker A, Ish-Horowicz D. Chick receptor tyrosine phosphatase Psi is dynamically expressed during somitogenesis. Gene Expression Patterns : Gep. 3: 325-9. PMID 12799079 DOI: 10.1016/S1567-133X(03)00038-3  0.326
2003 le Roux I, Lewis J, Ish-Horowicz D. Notch activity is required to maintain floorplate identity and to control neurogenesis in the chick hindbrain and spinal cord. The International Journal of Developmental Biology. 47: 263-72. PMID 12755331  0.613
2003 Bullock SL, Zicha D, Ish-Horowicz D. The Drosophila hairy RNA localization signal modulates the kinetics of cytoplasmic mRNA transport. The Embo Journal. 22: 2484-94. PMID 12743042 DOI: 10.1093/emboj/cdg230  0.662
2002 Morales AV, Yasuda Y, Ish-Horowicz D. Periodic Lunatic fringe expression is controlled during segmentation by a cyclic transcriptional enhancer responsive to notch signaling. Developmental Cell. 3: 63-74. PMID 12110168 DOI: 10.1016/S1534-5807(02)00211-3  0.445
2002 Bullock SL, Ish-Horowicz D. Cell polarity: Oskar seeks PARtner for a stable relationship. Nature Cell Biology. 4: E117-8. PMID 11988750 DOI: 10.1038/Ncb0502-E117  0.667
2001 Mailhos C, Modlich U, Lewis J, Harris A, Bicknell R, Ish-Horowicz D. Delta4, an endothelial specific notch ligand expressed at sites of physiological and tumor angiogenesis. Differentiation; Research in Biological Diversity. 69: 135-44. PMID 11798067 DOI: 10.1046/J.1432-0436.2001.690207.X  0.616
2001 Bullock SL, Ish-Horowicz D. Conserved signals and machinery for RNA transport in Drosophila oogenesis and embryogenesis. Nature. 414: 611-6. PMID 11740552 DOI: 10.1038/414611A  0.369
2001 Baker DA, Mille-Baker B, Wainwright SM, Ish-Horowicz D, Dibb NJ. Mae mediates MAP kinase phosphorylation of Ets transcription factors in Drosophila. Nature. 411: 330-4. PMID 11357138 DOI: 10.1038/35077122  0.382
2001 Hirsinger E, Malapert P, Dubrulle J, Delfini MC, Duprez D, Henrique D, Ish-Horowicz D, Pourquié O. Notch signalling acts in postmitotic avian myogenic cells to control MyoD activation. Development (Cambridge, England). 128: 107-16. PMID 11092816  0.626
2000 Jiang YJ, Aerne BL, Smithers L, Haddon C, Ish-Horowicz D, Lewis J. Notch signalling and the synchronization of the somite segmentation clock. Nature. 408: 475-9. PMID 11100729 DOI: 10.1038/35044091  0.663
2000 Firtel RA, Ish-Horowicz D. Differentiation and gene regulation. A rich developmental stew Current Opinion in Genetics & Development. 10: 469-70. PMID 10980422 DOI: 10.1016/S0959-437X(00)00114-3  0.394
2000 Jouve C, Palmeirim I, Henrique D, Beckers J, Gossler A, Ish-Horowicz D, Pourquié O. Notch signalling is required for cyclic expression of the hairy-like gene HES1 in the presomitic mesoderm. Development (Cambridge, England). 127: 1421-9. PMID 10704388  0.662
1999 Lall S, Francis-Lang H, Flament A, Norvell A, Schüpbach T, Ish-Horowicz D. Squid hnRNP protein promotes apical cytoplasmic transport and localization of Drosophila pair-rule transcripts. Cell. 98: 171-80. PMID 10428029 DOI: 10.1016/S0092-8674(00)81012-0  0.414
1999 Chadwick BP, Kidd T, Sgouros J, Ish-Horowicz D, Frischauf AM. Cloning, mapping and expression of UBL3, a novel ubiquitin-like gene. Gene. 233: 189-95. PMID 10375635 DOI: 10.1016/S0378-1119(99)00138-9  0.542
1999 Jiménez G, Verrijzer CP, Ish-Horowicz D. A conserved motif in goosecoid mediates groucho-dependent repression in Drosophila embryos. Molecular and Cellular Biology. 19: 2080-7. PMID 10022895 DOI: 10.1128/Mcb.19.3.2080  0.405
1998 Adam J, Myat A, Le Roux I, Eddison M, Henrique D, Ish-Horowicz D, Lewis J. Cell fate choices and the expression of Notch, Delta and Serrate homologues in the chick inner ear: parallels with Drosophila sense-organ development. Development (Cambridge, England). 125: 4645-54. PMID 9806914  0.617
1998 Palmeirim I, Dubrulle J, Henrique D, Ish-Horowicz D, Pourquié O. Uncoupling segmentation and somitogenesis in the chick presomitic mesoderm. Developmental Genetics. 23: 77-85. PMID 9706696 DOI: 10.1002/(Sici)1520-6408(1998)23:1<77::Aid-Dvg8>3.0.Co;2-3  0.686
1998 Crowe R, Henrique D, Ish-Horowicz D, Niswander L. A new role for Notch and Delta in cell fate decisions: patterning the feather array. Development (Cambridge, England). 125: 767-75. PMID 9435296  0.647
1997 Palmeirim I, Henrique D, Ish-Horowicz D, Pourquié O. Avian hairy gene expression identifies a molecular clock linked to vertebrate segmentation and somitogenesis. Cell. 91: 639-48. PMID 9393857 DOI: 10.1016/S0092-8674(00)80451-1  0.663
1997 Jiménez G, Paroush Z, Ish-Horowicz D. Groucho acts as a corepressor for a subset of negative regulators, including Hairy and Engrailed. Genes & Development. 11: 3072-82. PMID 9367988 DOI: 10.1101/Gad.11.22.3072  0.731
1997 Paroush Z, Wainwright SM, Ish-Horowicz D. Torso signalling regulates terminal patterning in Drosophila by antagonising Groucho-mediated repression. Development (Cambridge, England). 124: 3827-34. PMID 9367438  0.371
1997 Henrique D, Hirsinger E, Adam J, Le Roux I, Pourquié O, Ish-Horowicz D, Lewis J. Maintenance of neuroepithelial progenitor cells by Delta-Notch signalling in the embryonic chick retina. Current Biology : Cb. 7: 661-70. PMID 9285721 DOI: 10.1016/S0960-9822(06)00293-4  0.744
1997 Henrique D, Tyler D, Kintner C, Heath JK, Lewis JH, Ish-Horowicz D, Storey KG. cash4, a novel achaete-scute homolog induced by Hensen's node during generation of the posterior nervous system. Genes & Development. 11: 603-15. PMID 9119225 DOI: 10.1101/Gad.11.5.603  0.623
1996 Jiménez G, Pinchin SM, Ish-Horowicz D. In vivo interactions of the Drosophila Hairy and Runt transcriptional repressors with target promoters. The Embo Journal. 15: 7088-98. PMID 9003784  0.324
1996 Myat A, Henrique D, Ish-Horowicz D, Lewis J. A chick homologue of Serrate and its relationship with Notch and Delta homologues during central neurogenesis. Developmental Biology. 174: 233-47. PMID 8631496 DOI: 10.1006/Dbio.1996.0069  0.761
1995 Henrique D, Adam J, Myat A, Chitnis A, Lewis J, Ish-Horowicz D. Expression of a Delta homologue in prospective neurons in the chick. Nature. 375: 787-90. PMID 7596411 DOI: 10.1038/375787A0  0.757
1995 Chitnis A, Henrique D, Lewis J, Ish-Horowicz D, Kintner C. Primary neurogenesis in Xenopus embryos regulated by a homologue of the Drosophila neurogenic gene Delta. Nature. 375: 761-6. PMID 7596407 DOI: 10.1038/375761A0  0.73
1994 Paroush Z, Finley RL, Kidd T, Wainwright SM, Ingham PW, Brent R, Ish-Horowicz D. Groucho is required for Drosophila neurogenesis, segmentation, and sex determination and interacts directly with hairy-related bHLH proteins. Cell. 79: 805-15. PMID 8001118 DOI: 10.1016/0092-8674(94)90070-1  0.768
1991 Davis I, Ish-Horowicz D. Apical localization of pair-rule transcripts requires 3' sequences and limits protein diffusion in the Drosophila blastoderm embryo. Cell. 67: 927-40. PMID 1959136 DOI: 10.1016/0092-8674(91)90366-7  0.441
1990 Ish-Horowicz D, Davis I. Intracellular transcript localisation in early embryos Cell Biology International Reports. 14: 9. DOI: 10.1016/0309-1651(90)90146-P  0.352
1989 Ish-Horowicz D, Pinchin SM, Ingham PW, Gyurkovics HG. Autocatalytic ftz activation and metameric instability induced by ectopic ftz expression. Cell. 57: 223-32. PMID 2495181 DOI: 10.1016/0092-8674(89)90960-4  0.561
1987 Ish-Horowicz D, Pinchin SM. Pattern abnormalities induced by ectopic expression of the Drosophila gene hairy are associated with repression of ftz transcription. Cell. 51: 405-15. PMID 3664640 DOI: 10.1016/0092-8674(87)90636-2  0.31
1987 Flavell AJ, Dyson J, Ish-Horowicz D. A novel GC-rich dispersed repeat sequence in Drosophila melanogaster. Nucleic Acids Research. 15: 4035-48. PMID 2884623 DOI: 10.1093/Nar/15.10.4035  0.347
1986 Sinclair JH, Burke JF, Ish-Horowicz D, Sang JH. Functional analysis of the transcriptional control regions of the copia transposable element. The Embo Journal. 5: 2349-2354. PMID 16453706 DOI: 10.1002/J.1460-2075.1986.Tb04503.X  0.575
1986 Ingham PW, Ish-Horowicz D, Howard KR. Correlative changes in homoeotic and segmentation gene expression in Krüppel mutant embryos of Drosophila. The Embo Journal. 5: 1659-65. PMID 16453692 DOI: 10.1002/J.1460-2075.1986.Tb04409.X  0.573
1985 Ingham PW, Pinchin SM, Howard KR, Ish-Horowicz D. Genetic Analysis of the Hairy Locus in DROSOPHILA MELANOGASTER. Genetics. 111: 463-86. PMID 17246301  0.518
1985 Ish-Horowicz D, Howard KR, Pinchin SM, Ingham PW. Molecular and genetic analysis of the hairy locus in Drosophila. Cold Spring Harbor Symposia On Quantitative Biology. 50: 135-44. PMID 3006986 DOI: 10.1101/Sqb.1985.050.01.019  0.45
1985 Ingham PW, Howard KR, Ish-Horowicz D. Transcription pattern of the Drosophila segmentation gene hairy Nature. 318: 439-445. DOI: 10.1038/318439a0  0.587
1984 Burke JF, Pinchin SM, Ish-Horowicz D, Sinclair JH, Sang JH. Integration of Drosophila heat-shock genes transfected into cultured Drosophila melanogaster cells. Somatic Cell and Molecular Genetics. 10: 579-88. PMID 6438809 DOI: 10.1007/BF01535223  0.562
1984 Sang JH, Sinclair JH, Burke JF, Ish-Horowicz D. Rescue of a Drosophila temperature-sensitive mutant cell line by DNA transfection. Somatic Cell and Molecular Genetics. 10: 573-7. PMID 6438808 DOI: 10.1007/BF01535222  0.529
1984 Burke JF, Sinclair JH, Sang JH, Ish-Horowicz D. An assay for transient gene expression in transfected Drosophila cells, using [3H]guanine incorporation. The Embo Journal. 3: 2549-54. PMID 6096129 DOI: 10.1002/J.1460-2075.1984.Tb02172.X  0.611
1983 Flavell AJ, Ish-Horowicz D. The origin of extrachromosomal circular copia elements. Cell. 34: 415-9. PMID 6616617 DOI: 10.1016/0092-8674(83)90375-6  0.3
1982 Ish-Horowicz D. Somatic gene amplification during Drosophila oogenesis. Nature. 296: 806-7. PMID 6803174 DOI: 10.1038/296806A0  0.358
1982 Burke JF, Ish-Horowicz D. Expression of Drosophila heat shock genes is regulated in Rat-cells. Nucleic Acids Research. 10: 3821-30. PMID 6287421 DOI: 10.1093/Nar/10.13.3821  0.337
1982 Udvardy A, Sümegi J, Tóth EC, Gausz J, Gyurkovics H, Schedl P, Ish-Horowicz D. Genomic organization and functional analysis of a deletion variant of the 87A7 heat shock locus of Drosophila melanogaster. Journal of Molecular Biology. 155: 267-80. PMID 6281448 DOI: 10.1016/0022-2836(82)90005-5  0.56
1981 Flavell AJ, Ish-Horowicz D. Extrachromosomal circular copies of the eukaryotic transposable element copia in cultured Drosophila cells. Nature. 292: 591-5. PMID 6265802 DOI: 10.1038/292591A0  0.302
1980 Ish-Horowicz D, Pinchin SM. Genomic organization of the 87A7 and 87Cl heat-induced loci of Drosophila melanogaster. Journal of Molecular Biology. 142: 231-45. PMID 6255167 DOI: 10.1016/0022-2836(80)90047-9  0.355
1979 Ish-Horowicz D, Pinchin SM, Schedl P, Artavanis-Tsakonas S, Mirault ME. Genetic and molecular analysis of the 87A7 and 87C1 heat-inducible loci of D. melanogaster. Cell. 18: 1351-8. PMID 117906 DOI: 10.1016/0092-8674(79)90245-9  0.676
1979 Ish-Horowicz D, Pinchin SM, Gausz J, Gyurkovics H, Bencze G, Goldschmidt-Clermont M, Holden JJ. Deletion mapping of two D. melanogaster loci that code for the 70,000 dalton heat-induced protein. Cell. 17: 565-71. PMID 113104 DOI: 10.1016/0092-8674(79)90264-2  0.557
1977 Ish-Horowicz D, Holden JJ, Gehring WJ. Deletions of two heat-activated loci in Drosophila melanogaster and their effects on heat-induced protein synthesis. Cell. 12: 643-52. PMID 411575 DOI: 10.1016/0092-8674(77)90264-1  0.643
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