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Hiromasa Funato - Publications

Affiliations: 
Toho University, Ōta-ku, Tōkyō-to, Japan 
Area:
Neuroanatomy
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34 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Nakai A, Kashiwagi M, Fujiyama T, Iwasaki K, Hirano A, Funato H, Yanagisawa M, Sakurai T, Hayashi Y. Crucial role of TFAP2B in the nervous system for regulating NREM sleep. Molecular Brain. 17: 13. PMID 38413970 DOI: 10.1186/s13041-024-01084-8  0.322
2023 Elhosainy A, Suzuki-Abe H, Kaushik MK, Kim SJ, Saitoh T, Ishikawa Y, Hotta-Hirashima N, Miyoshi C, Funato H, Yanagisawa M. Face validation and pharmacologic analysis of Sik3 mutant mouse as a possible model of idiopathic hypersomnia. European Journal of Pharmacology. 175877. PMID 37356786 DOI: 10.1016/j.ejphar.2023.175877  0.311
2022 Kim SJ, Hotta-Hirashima N, Asano F, Kitazono T, Iwasaki K, Nakata S, Komiya H, Asama N, Matsuoka T, Fujiyama T, Ikkyu A, Kakizaki M, Kanno S, Choi J, Kumar D, ... ... Funato H, et al. Kinase signalling in excitatory neurons regulates sleep quantity and depth. Nature. PMID 36477539 DOI: 10.1038/s41586-022-05450-1  0.314
2022 Zhou R, Wang G, Li Q, Meng F, Liu C, Gan R, Ju D, Liao M, Xu J, Sang D, Gao X, Zhou S, Wu K, Sun Q, Guo Y, ... ... Funato H, et al. A signalling pathway for transcriptional regulation of sleep amount in mice. Nature. PMID 36477534 DOI: 10.1038/s41586-022-05510-6  0.312
2022 Fujiyama T, Takenaka H, Asano F, Miyanishi K, Hotta-Hirashima N, Ishikawa Y, Kanno S, Seoane-Collazo P, Miwa H, Hoshino M, Yanagisawa M, Funato H. Mice Lacking Cerebellar Cortex and Related Structures Show a Decrease in Slow-Wave Activity With Normal Non-REM Sleep Amount and Sleep Homeostasis. Frontiers in Behavioral Neuroscience. 16: 910461. PMID 35722192 DOI: 10.3389/fnbeh.2022.910461  0.31
2021 Tsuneoka Y, Funato H. Cellular Composition of the Preoptic Area Regulating Sleep, Parental, and Sexual Behavior. Frontiers in Neuroscience. 15: 649159. PMID 33867927 DOI: 10.3389/fnins.2021.649159  0.303
2021 Iwasaki K, Fujiyama T, Nakata S, Park M, Mioshi C, Hotta-Hirashima N, Ikkyu A, Kakizaki M, Sugiyama F, Mizuno S, Abe M, Sakimura K, Takahashi S, Funato H, Yanagisawa M. Induction of mutant allele in neurons in late infancy increases sleep need. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 33558433 DOI: 10.1523/JNEUROSCI.1004-20.2020  0.325
2020 Nakai A, Fujiyama T, Nagata N, Kashiwagi M, Ikkyu A, Takagi M, Tatsuzawa C, Tanaka K, Kakizaki M, Kanuka M, Kawano T, Mizuno S, Sugiyama F, Takahashi S, Funato H, et al. Sleep Architecture in Mice Is Shaped by the Transcription Factor AP-2β. Genetics. PMID 32878901 DOI: 10.1534/Genetics.120.303435  0.425
2020 Hirose Y, Kitazono T, Sezaki M, Abe M, Sakimura K, Funato H, Handa H, Vogt KE, Yanagisawa M. Hypnotic effect of thalidomide is independent of teratogenic ubiquitin/proteasome pathway. Proceedings of the National Academy of Sciences of the United States of America. PMID 32848052 DOI: 10.1073/Pnas.1917701117  0.373
2020 Honda T, Takata Y, Cherasse Y, Mizuno S, Sugiyama F, Takahashi S, Funato H, Yanagisawa M, Lazarus M, Oishi Y. Ablation of Ventral Midbrain/Pons GABA Neurons Induces Mania-like Behaviors with Altered Sleep Homeostasis and Dopamine DR-mediated Sleep Reduction. Iscience. 23: 101240. PMID 32563157 DOI: 10.1016/J.Isci.2020.101240  0.421
2020 Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Honda T, Choi J, Asano F, Mizuno S, Takahashi S, Yanagisawa M, Funato H. Loss of the conserved PKA sites of SIK1 and SIK2 increases sleep need. Scientific Reports. 10: 8676. PMID 32457359 DOI: 10.1038/S41598-020-65647-0  0.421
2019 Yamabe M, Horie K, Shiokawa H, Funato H, Yanagisawa M, Kitagawa H. MC-SleepNet: Large-scale Sleep Stage Scoring in Mice by Deep Neural Networks. Scientific Reports. 9: 15793. PMID 31672998 DOI: 10.1038/S41598-019-51269-8  0.334
2019 Kakizaki M, Tsuneoka Y, Takase K, Kim SJ, Choi J, Ikkyu A, Abe M, Sakimura K, Yanagisawa M, Funato H. Differential Roles of Each Orexin Receptor Signaling in Obesity. Iscience. 20: 1-13. PMID 31546102 DOI: 10.1016/J.Isci.2019.09.003  0.324
2019 Furuse T, Mizuma H, Hirose Y, Kushida T, Yamada I, Miura I, Masuya H, Funato H, Yanagisawa M, Onoe H, Wakana S. A new mouse model of GLUT1-deficiency syndrome exhibits abnormal sleep-wake patterns and alterations of glucose kinetics in the brain. Disease Models & Mechanisms. PMID 31399478 DOI: 10.1242/Dmm.038828  0.347
2019 Miyoshi C, Kim SJ, Ezaki T, Ikkyu A, Hotta-Hirashima N, Kanno S, Kakizaki M, Yamada M, Wakana S, Yanagisawa M, Funato H. Methodology and theoretical basis of forward genetic screening for sleep/wakefulness in mice. Proceedings of the National Academy of Sciences of the United States of America. PMID 31337678 DOI: 10.1073/Pnas.1906774116  0.399
2019 Kim SJ, Miyoshi C, Ezaki T, Ikkyu A, Hotta-Hirashima N, Kanno S, Kakizaki M, Yamada M, Wakana S, Funato H, Yanagisawa M. A step towards demystifying sleep physiology: Forward genetics approach in mice Ibro Reports. 6. DOI: 10.1016/J.Ibror.2019.07.534  0.378
2019 Park M, Miyoshi C, Fujiyama T, Kakizaki M, Ikkyu A, Choi J, Mizuno S, Takahashi S, Funato H, Yanagisawa M. Increased sleep need in mice lacking the PKA phosphorylation site in SIK1 and SIK2 Ibro Reports. 6. DOI: 10.1016/J.Ibror.2019.07.245  0.372
2018 Honda T, Fujiyama T, Miyoshi C, Ikkyu A, Hotta-Hirashima N, Kanno S, Mizuno S, Sugiyama F, Takahashi S, Funato H, Yanagisawa M. A single phosphorylation site of SIK3 regulates daily sleep amounts and sleep need in mice. Proceedings of the National Academy of Sciences of the United States of America. 115: 10458-10463. PMID 30254177 DOI: 10.1073/Pnas.1810823115  0.41
2018 Iwasaki K, Komiya H, Kakizaki M, Miyoshi C, Abe M, Sakimura K, Funato H, Yanagisawa M. Ablation of central serotonergic neurons decreased REM sleep and attenuated arousal response Frontiers in Neuroscience. 12: 535. PMID 30131671 DOI: 10.3389/Fnins.2018.00535  0.398
2018 Shigiyama F, Kumashiro N, Tsuneoka Y, Igarashi H, Yoshikawa F, Kakehi S, Funato H, Hirose T. Mechanisms of sleep deprivation-induced hepatic steatosis and insulin resistance in mice. American Journal of Physiology-Endocrinology and Metabolism. 315. PMID 29989853 DOI: 10.1152/Ajpendo.00072.2018  0.37
2018 Wang Z, Ma J, Miyoshi C, Li Y, Sato M, Ogawa Y, Lou T, Ma C, Gao X, Lee C, Fujiyama T, Yang X, Zhou S, Hotta-Hirashima N, Klewe-Nebenius D, ... ... Funato H, et al. Quantitative phosphoproteomic analysis of the molecular substrates of sleep need. Nature. PMID 29899451 DOI: 10.1038/S41586-018-0218-8  0.395
2018 Komiya H, Miyoshi C, Iwasaki K, Hotta-Hirashima N, Ikkyu A, Kanno S, Honda T, Gosho M, Hamada H, Satoh T, Fukamizu A, Funato H, Yanagisawa M. Sleep/Wake Behaviors in Mice During Pregnancy and Pregnancy-Associated Hypertensive Mice. Sleep. 41. PMID 29309677 DOI: 10.1093/Sleep/Zsx209  0.37
2018 Shigiyama F, Kumashiro N, Yoshikawa F, Tsuneoka Y, Funato H, Hirose T. Mechanisms of Hepatic Steatosis and Insulin Resistance Induced by Sleep Deprivation in Mice Diabetes. 67. DOI: 10.2337/Db18-1848-P  0.331
2017 Tsuneoka Y, Yoshida S, Takase K, Oda S, Kuroda M, Funato H. Neurotransmitters and neuropeptides in gonadal steroid receptor-expressing cells in medial preoptic area subregions of the male mouse. Scientific Reports. 7: 9809. PMID 28852050 DOI: 10.1038/S41598-017-10213-4  0.321
2016 Funato H, Miyoshi C, Fujiyama T, Kanda T, Sato M, Wang Z, Ma J, Nakane S, Tomita J, Ikkyu A, Kakizaki M, Hotta-Hirashima N, Kanno S, Komiya H, Asano F, et al. Forward-genetics analysis of sleep in randomly mutagenized mice. Nature. PMID 27806374 DOI: 10.1038/Nature20142  0.405
2016 Kanda T, Tsujino N, Kuramoto E, Koyama Y, Susaki EA, Chikahisa S, Funato H. Sleep as a biological problem: an overview of frontiers in sleep research Journal of Physiological Sciences. 66: 1-13. DOI: 10.1007/S12576-015-0414-3  0.38
2014 Wang Z, Liu S, Kakizaki M, Hirose Y, Ishikawa Y, Funato H, Yanagisawa M, Yu Y, Liu Q. Orexin/hypocretin activates mTOR complex 1 (mTORC1) via an Erk/Akt-independent and calcium-stimulated lysosome v-ATPase pathway. The Journal of Biological Chemistry. 289: 31950-9. PMID 25278019 DOI: 10.1074/Jbc.M114.600015  0.341
2014 Takase K, Kikuchi K, Tsuneoka Y, Oda S, Kuroda M, Funato H. Meta-analysis of melanin-concentrating hormone signaling-deficient mice on behavioral and metabolic phenotypes. Plos One. 9: e99961. PMID 24924345 DOI: 10.1371/Journal.Pone.0099961  0.346
2010 Funato H, Sato M, Sinton CM, Gautron L, Williams SC, Skach A, Elmquist JK, Skoultchi AI, Yanagisawa M. Loss of Goosecoid-like and DiGeorge syndrome critical region 14 in interpeduncular nucleus results in altered regulation of rapid eye movement sleep. Proceedings of the National Academy of Sciences of the United States of America. 107: 18155-60. PMID 20921407 DOI: 10.1073/Pnas.1012764107  0.417
2010 Otsuki K, Uchida S, Wakabayashi Y, Matsubara T, Hobara T, Funato H, Watanabe Y. Aberrant REST-mediated transcriptional regulation in major depressive disorder. Journal of Psychiatric Research. 44: 378-84. PMID 19846118 DOI: 10.1016/J.Jpsychires.2009.09.009  0.301
2010 Hobara T, Uchida S, Otsuki K, Matsubara T, Funato H, Matsuo K, Suetsugi M, Watanabe Y. Altered gene expression of histone deacetylases in mood disorder patients. Journal of Psychiatric Research. 44: 263-70. PMID 19767015 DOI: 10.1016/J.Jpsychires.2009.08.015  0.312
2010 Funato H, Sato M, Sinton CM, Gautron L, Williams SC, Elmquist JK, Kuroda M, Skoultchi AI, Yanagisawa M. Loss of Goosecoid-like and Dgcr14 in interpeduncular nucleus alters the expression of REM sleep Neuroscience Research. 68. DOI: 10.1016/J.Neures.2010.07.109  0.393
2008 Kelz MB, Sun Y, Chen J, Cheng Meng Q, Moore JT, Veasey SC, Dixon S, Thornton M, Funato H, Yanagisawa M. An essential role for orexins in emergence from general anesthesia. Proceedings of the National Academy of Sciences of the United States of America. 105: 1309-14. PMID 18195361 DOI: 10.1073/Pnas.0707146105  0.33
2006 Funato H, Kobayashi A, Watanabe Y. Differential effects of antidepressants on dexamethasone-induced nuclear translocation and expression of glucocorticoid receptor. Brain Research. 1117: 125-34. PMID 16956592 DOI: 10.1016/J.Brainres.2006.08.029  0.325
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