James M. Laird, Ph.D. - Publications

Affiliations: 
2007 Case Western Reserve University, Cleveland Heights, OH, United States 
Area:
Organic Chemistry

17 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2019 Bi W, Jang GF, Zhang L, Crabb JW, Laird J, Linetsky M, Salomon RG. The Adductomics of Isolevuglandins: Oxidation of IsoLG Pyrrole Intermediates Generates Pyrrole⁻Pyrrole Crosslinks and Lactams. High-Throughput. 8. PMID 31083423 DOI: 10.3390/ht8020012  0.725
2016 Bi W, Jang GF, Zhang L, Crabb JW, Laird J, Linetsky MD, Salomon RG. Molecular Structures of Isolevuglandin-protein Cross Links. Chemical Research in Toxicology. PMID 27599534 DOI: 10.1021/Acs.Chemrestox.6B00141  0.703
2014 Saeed AM, Duffort S, Ivanov D, Wang H, Laird JM, Salomon RG, Cruz-Guilloty F, Perez VL. The oxidative stress product carboxyethylpyrrole potentiates TLR2/TLR1 inflammatory signaling in macrophages. Plos One. 9: e106421. PMID 25184331 DOI: 10.1371/Journal.Pone.0106421  0.583
2014 Cruz-Guilloty F, Saeed AM, Duffort S, Cano M, Ebrahimi KB, Ballmick A, Tan Y, Wang H, Laird JM, Salomon RG, Handa JT, Perez VL. T cells and macrophages responding to oxidative damage cooperate in pathogenesis of a mouse model of age-related macular degeneration. Plos One. 9: e88201. PMID 24586307 DOI: 10.1371/Journal.Pone.0088201  0.591
2013 Cruz-Guilloty F, Saeed AM, Echegaray JJ, Duffort S, Ballmick A, Tan Y, Betancourt M, Viteri E, Ramkhellawan GC, Ewald E, Feuer W, Huang D, Wen R, Hong L, Wang H, ... Laird JM, et al. Infiltration of proinflammatory m1 macrophages into the outer retina precedes damage in a mouse model of age-related macular degeneration. International Journal of Inflammation. 2013: 503725. PMID 23533946 DOI: 10.1155/2013/503725  0.646
2013 Charvet CD, Laird J, Xu Y, Salomon RG, Pikuleva IA. Posttranslational modification by an isolevuglandin diminishes activity of the mitochondrial cytochrome P450 27A1. Journal of Lipid Research. 54: 1421-9. PMID 23479405 DOI: 10.1194/Jlr.M035790  0.654
2012 Poliakov E, Gubin A, Laird J, Gentleman S, Salomon RG, Redmond TM. The mechanism of fenretinide (4-HPR) inhibition of β-carotene monooxygenase 1. New suspect for the visual side effects of fenretinide. Advances in Experimental Medicine and Biology. 723: 167-74. PMID 22183330 DOI: 10.1007/978-1-4614-0631-0_23  0.549
2011 Gu X, Zhang W, Choi J, Li W, Chen X, Laird JM, Salomon RG. An (1)O2 route to γ-hydroxyalkenal phospholipids by vitamin E-induced fragmentation of hydroperoxydiene-derived endoperoxides. Chemical Research in Toxicology. 24: 1080-93. PMID 21568309 DOI: 10.1021/Tx200093M  0.761
2011 Charvet C, Liao WL, Heo GY, Laird J, Salomon RG, Turko IV, Pikuleva IA. Isolevuglandins and mitochondrial enzymes in the retina: mass spectrometry detection of post-translational modification of sterol-metabolizing CYP27A1. The Journal of Biological Chemistry. 286: 20413-22. PMID 21498512 DOI: 10.1074/Jbc.M111.232546  0.635
2011 Choi J, Laird JM, Salomon RG. An efficient synthesis of γ-hydroxy-α,β-unsaturated aldehydic esters of 2-lysophosphatidylcholine. Bioorganic & Medicinal Chemistry. 19: 580-7. PMID 21123073 DOI: 10.1016/J.Bmc.2010.10.058  0.667
2011 Choi J, Zhang W, Gu X, Chen X, Hong L, Laird JM, Salomon RG. Lysophosphatidylcholine is generated by spontaneous deacylation of oxidized phospholipids. Chemical Research in Toxicology. 24: 111-8. PMID 20973507 DOI: 10.1021/Tx100305B  0.747
2010 Mesaros C, Gugiu BG, Zhou R, Lee SH, Choi J, Laird J, Blair IA, Salomon RG. A 13-Oxo-9,10-epoxytridecenoate phospholipid analogue of the genotoxic 4,5-epoxy-2E-decenal: detection in vivo, chemical synthesis, and adduction with DNA. Chemical Research in Toxicology. 23: 516-27. PMID 20131875 DOI: 10.1021/Tx9002484  0.742
2009 Lu L, Gu X, Hong L, Laird J, Jaffe K, Choi J, Crabb J, Salomon RG. Synthesis and structural characterization of carboxyethylpyrrole-modified proteins: mediators of age-related macular degeneration. Bioorganic & Medicinal Chemistry. 17: 7548-61. PMID 19786352 DOI: 10.1016/J.Bmc.2009.09.009  0.752
2009 Li W, Laird JM, Lu L, Roychowdhury S, Nagy LE, Zhou R, Crabb JW, Salomon RG. Isolevuglandins covalently modify phosphatidylethanolamines in vivo: detection and quantitative analysis of hydroxylactam adducts. Free Radical Biology & Medicine. 47: 1539-52. PMID 19751823 DOI: 10.1016/J.Freeradbiomed.2009.09.003  0.666
2008 Govindarajan B, Laird J, Sherman R, Salomon RG, Bhattacharya SK. Neuroprotection in glaucoma using calpain-1 inhibitors: regional differences in calpain-1 activity in the trabecular meshwork, optic nerve and implications for therapeutics. Cns & Neurological Disorders Drug Targets. 7: 295-304. PMID 18673213 DOI: 10.2174/187152708784936644  0.705
2008 Chen X, Zhang W, Laird J, Hazen SL, Salomon RG. Polyunsaturated phospholipids promote the oxidation and fragmentation of gamma-hydroxyalkenals: formation and reactions of oxidatively truncated ether phospholipids. Journal of Lipid Research. 49: 832-46. PMID 18165704 DOI: 10.1194/Jlr.M700598-Jlr200  0.672
2008 Govindarajan B, Laird J, Salomon RG, Bhattacharya SK. Isolevuglandin-modified proteins, including elevated levels of inactive calpain-1, accumulate in glaucomatous trabecular meshwork. Biochemistry. 47: 817-25. PMID 18085799 DOI: 10.1021/Bi701517M  0.723
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