| Year |
Citation |
Score |
| 2023 |
Ma CH, Kumar D, Jayaram M, Ghosh SK, Iyer VR. The selfish yeast plasmid exploits a SWI/SNF-type chromatin remodeling complex for hitchhiking on chromosomes and ensuring high-fidelity propagation. Plos Genetics. 19: e1010986. PMID 37812641 DOI: 10.1371/journal.pgen.1010986 |
0.427 |
|
| 2021 |
Ma CH, Javanmardi K, Finkelstein IJ, Jayaram M. Disintegration promotes protospacer integration by the Cas1-Cas2 complex. Elife. 10. PMID 34435949 DOI: 10.7554/eLife.65763 |
0.363 |
|
| 2021 |
Kumar D, Prajapati HK, Mahilkar A, Ma CH, Mittal P, Jayaram M, Ghosh SK. The selfish yeast plasmid utilizes the condensin complex and condensed chromatin for faithful partitioning. Plos Genetics. 17: e1009660. PMID 34270553 DOI: 10.1371/journal.pgen.1009660 |
0.435 |
|
| 2020 |
Fan HF, Su BY, Ma CH, Rowley PA, Jayaram M. A bipartite thermodynamic-kinetic contribution by an activating mutation to RDF-independent excision by a phage serine integrase. Nucleic Acids Research. PMID 32479633 DOI: 10.1093/Nar/Gkaa401 |
0.344 |
|
| 2019 |
Ma CH, Su BY, Maciaszek A, Fan HF, Guga P, Jayaram M. A Flp-SUMO hybrid recombinase reveals multi-layered copy number control of a selfish DNA element through post-translational modification. Plos Genetics. 15: e1008193. PMID 31242181 DOI: 10.1371/Journal.Pgen.1008193 |
0.562 |
|
| 2019 |
Sau S, Ghosh SK, Liu YT, Ma CH, Jayaram M. Hitchhiking on chromosomes: A persistence strategy shared by diverse selfish DNA elements. Plasmid. PMID 30726706 DOI: 10.1016/J.Plasmid.2019.01.004 |
0.522 |
|
| 2018 |
Fan HF, Ma CH, Jayaram M. Single-Molecule Tethered Particle Motion: Stepwise Analyses of Site-Specific DNA Recombination. Micromachines. 9. PMID 30424148 DOI: 10.3390/Mi9050216 |
0.471 |
|
| 2016 |
Xia J, Chen LT, Mei Q, Ma CH, Halliday JA, Lin HY, Magnan D, Pribis JP, Fitzgerald DM, Hamilton HM, Richters M, Nehring RB, Shen X, Li L, Bates D, ... ... Jayaram M, et al. Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase. Science Advances. 2: e1601605. PMID 28090586 DOI: 10.1126/Sciadv.1601605 |
0.476 |
|
| 2016 |
Fan HF, Hsieh TS, Ma CH, Jayaram M. Single-molecule analysis of ϕC31 integrase-mediated site-specific recombination by tethered particle motion. Nucleic Acids Research. 44: 10804-10823. PMID 27986956 DOI: 10.1093/Nar/Gkw861 |
0.485 |
|
| 2016 |
Liu YT, Chang KM, Ma CH, Jayaram M. Replication-dependent and independent mechanisms for the chromosome-coupled persistence of a selfish genome. Nucleic Acids Research. PMID 27492289 DOI: 10.1093/Nar/Gkw694 |
0.504 |
|
| 2015 |
Sau S, Liu YT, Ma CH, Jayaram M. Stable persistence of the yeast plasmid by hitchhiking on chromosomes during vegetative and germ-line divisions of host cells. Mobile Genetic Elements. 5: 1-8. PMID 26442178 DOI: 10.1080/2159256X.2015.1031359 |
0.483 |
|
| 2015 |
Jayaram M, Ma CH, Kachroo AH, Rowley PA, Guga P, Fan HF, Voziyanov Y. An Overview of Tyrosine Site-specific Recombination: From an Flp Perspective. Microbiology Spectrum. 3. PMID 26350308 DOI: 10.1128/Microbiolspec.Mdna3-0021-2014 |
0.478 |
|
| 2015 |
Cannon B, Kachroo AH, Jarmoskaite I, Jayaram M, Russell R. Hexapeptides That Inhibit Processing of Branched DNA Structures Induce a Dynamic Ensemble of Holliday Junction Conformations. The Journal of Biological Chemistry. 290: 22734-46. PMID 26209636 DOI: 10.1074/Jbc.M115.663930 |
0.334 |
|
| 2015 |
Rowley PA, Kachroo AH, Ma CH, Maciaszek AD, Guga P, Jayaram M. Stereospecific suppression of active site mutants by methylphosphonate substituted substrates reveals the stereochemical course of site-specific DNA recombination. Nucleic Acids Research. 43: 6023-37. PMID 25999343 DOI: 10.1093/Nar/Gkv513 |
0.409 |
|
| 2015 |
Fan HF, Cheng YS, Ma CH, Jayaram M. Single molecule TPM analysis of the catalytic pentad mutants of Cre and Flp site-specific recombinases: contributions of the pentad residues to the pre-chemical steps of recombination. Nucleic Acids Research. 43: 3237-55. PMID 25765648 DOI: 10.1093/Nar/Gkv114 |
0.406 |
|
| 2014 |
Yen-Ting-Liu, Sau S, Ma CH, Kachroo AH, Rowley PA, Chang KM, Fan HF, Jayaram M. The partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells. Microbiology Spectrum. 2. PMID 25541598 DOI: 10.1128/microbiolspec.PLAS-0003-2013 |
0.461 |
|
| 2014 |
Sau S, Conrad MN, Lee CY, Kaback DB, Dresser ME, Jayaram M. A selfish DNA element engages a meiosis-specific motor and telomeres for germ-line propagation. The Journal of Cell Biology. 205: 643-61. PMID 24914236 DOI: 10.1083/Jcb.201312002 |
0.517 |
|
| 2014 |
Ma CH, Liu YT, Savva CG, Rowley PA, Cannon B, Fan HF, Russell R, Holzenburg A, Jayaram M. Organization of DNA partners and strand exchange mechanisms during Flp site-specific recombination analyzed by difference topology, single molecule FRET and single molecule TPM. Journal of Molecular Biology. 426: 793-815. PMID 24286749 DOI: 10.1016/J.Jmb.2013.11.017 |
0.449 |
|
| 2013 |
Jayaram M. Mathematical validation of a biological model for unlinking replication catenanes by recombination. Proceedings of the National Academy of Sciences of the United States of America. 110: 20854-5. PMID 24335590 DOI: 10.1073/Pnas.1321214111 |
0.498 |
|
| 2013 |
Fan HF, Ma CH, Jayaram M. Real-time single-molecule tethered particle motion analysis reveals mechanistic similarities and contrasts of Flp site-specific recombinase with Cre and λ Int. Nucleic Acids Research. 41: 7031-47. PMID 23737451 DOI: 10.1093/Nar/Gkt424 |
0.49 |
|
| 2013 |
Chan KM, Liu YT, Ma CH, Jayaram M, Sau S. The 2 micron plasmid of Saccharomyces cerevisiae: a miniaturized selfish genome with optimized functional competence. Plasmid. 70: 2-17. PMID 23541845 DOI: 10.1016/J.Plasmid.2013.03.001 |
0.581 |
|
| 2013 |
Jayaram M, Chang KM, Ma CH, Huang CC, Liu YT, Sau S. Topological similarity between the 2μm plasmid partitioning locus and the budding yeast centromere: evidence for a common evolutionary origin? Biochemical Society Transactions. 41: 501-7. PMID 23514143 DOI: 10.1042/Bst20120224 |
0.516 |
|
| 2013 |
Liu YT, Ma CH, Jayaram M. Co-segregation of yeast plasmid sisters under monopolin-directed mitosis suggests association of plasmid sisters with sister chromatids. Nucleic Acids Research. 41: 4144-58. PMID 23423352 DOI: 10.1093/Nar/Gkt096 |
0.525 |
|
| 2013 |
Ma CH, Cui H, Hajra S, Rowley PA, Fekete C, Sarkeshik A, Ghosh SK, Yates JR, Jayaram M. Temporal sequence and cell cycle cues in the assembly of host factors at the yeast 2 micron plasmid partitioning locus. Nucleic Acids Research. 41: 2340-53. PMID 23275556 DOI: 10.1093/Nar/Gks1338 |
0.604 |
|
| 2011 |
Jayaram M. Association of a centromere specific nucleosome with the yeast plasmid partitioning locus: Implications beyond plasmid partitioning. Mobile Genetic Elements. 1: 203-207. PMID 22479687 DOI: 10.4161/Mge.1.3.17431 |
0.47 |
|
| 2011 |
Huang CC, Chang KM, Cui H, Jayaram M. Histone H3-variant Cse4-induced positive DNA supercoiling in the yeast plasmid has implications for a plasmid origin of a chromosome centromere. Proceedings of the National Academy of Sciences of the United States of America. 108: 13671-6. PMID 21807992 DOI: 10.1073/Pnas.1101944108 |
0.641 |
|
| 2011 |
Huang CC, Hajra S, Ghosh SK, Jayaram M. Cse4 (CenH3) association with the Saccharomyces cerevisiae plasmid partitioning locus in its native and chromosomally integrated states: implications in centromere evolution. Molecular and Cellular Biology. 31: 1030-40. PMID 21173161 DOI: 10.1128/Mcb.01191-10 |
0.512 |
|
| 2010 |
Rowley PA, Kachroo AH, Ma CH, Maciaszek AD, Guga P, Jayaram M. Electrostatic suppression allows tyrosine site-specific recombination in the absence of a conserved catalytic arginine. The Journal of Biological Chemistry. 285: 22976-85. PMID 20448041 DOI: 10.1074/jbc.M110.112292 |
0.305 |
|
| 2010 |
Ghosh SK, Huang CC, Hajra S, Jayaram M. Yeast cohesin complex embraces 2 micron plasmid sisters in a tri-linked catenane complex. Nucleic Acids Research. 38: 570-84. PMID 19920123 DOI: 10.1093/Nar/Gkp993 |
0.543 |
|
| 2009 |
Ma CH, Kachroo AH, Macieszak A, Chen TY, Guga P, Jayaram M. Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase. Plos One. 4: e7248. PMID 19789629 DOI: 10.1371/journal.pone.0007248 |
0.342 |
|
| 2009 |
Ma CH, Rowley PA, Macieszak A, Guga P, Jayaram M. Active site electrostatics protect genome integrity by blocking abortive hydrolysis during DNA recombination. The Embo Journal. 28: 1745-56. PMID 19440204 DOI: 10.1038/emboj.2009.131 |
0.381 |
|
| 2009 |
Cui H, Ghosh SK, Jayaram M. The selfish yeast plasmid uses the nuclear motor Kip1p but not Cin8p for its localization and equal segregation. The Journal of Cell Biology. 185: 251-64. PMID 19364922 DOI: 10.1083/Jcb.200810130 |
0.603 |
|
| 2007 |
Ghosh SK, Hajra S, Jayaram M. Faithful segregation of the multicopy yeast plasmid through cohesin-mediated recognition of sisters. Proceedings of the National Academy of Sciences of the United States of America. 104: 13034-9. PMID 17670945 DOI: 10.1073/Pnas.0702996104 |
0.553 |
|
| 2007 |
Yin Z, Suzuki A, Lou Z, Jayaram M, Harshey RM. Interactions of phage Mu enhancer and termini that specify the assembly of a topologically unique interwrapped transpososome. Journal of Molecular Biology. 372: 382-96. PMID 17669422 DOI: 10.1016/J.Jmb.2007.06.086 |
0.374 |
|
| 2007 |
Jayaram M. Split target specificity of ResT: a design for protein delivery, site selectivity and regulation of enzyme activity? Molecular Microbiology. 64: 575-9. PMID 17462008 DOI: 10.1111/j.1365-2958.2007.05700.x |
0.379 |
|
| 2007 |
Ma CH, Kwiatek A, Bolusani S, Voziyanov Y, Jayaram M. Unveiling hidden catalytic contributions of the conserved His/Trp-III in tyrosine recombinases: assembly of a novel active site in Flp recombinase harboring alanine at this position. Journal of Molecular Biology. 368: 183-96. PMID 17367810 DOI: 10.1016/J.Jmb.2007.02.022 |
0.388 |
|
| 2007 |
Du Q, Livshits A, Kwiatek A, Jayaram M, Vologodskii A. Protein-induced local DNA bends regulate global topology of recombination products. Journal of Molecular Biology. 368: 170-82. PMID 17337001 DOI: 10.1016/J.Jmb.2007.02.010 |
0.409 |
|
| 2006 |
Harshey RM, Jayaram M. The mu transpososome through a topological lens. Critical Reviews in Biochemistry and Molecular Biology. 41: 387-405. PMID 17092824 DOI: 10.1080/10409230600946015 |
0.5 |
|
| 2006 |
Bolusani S, Ma CH, Paek A, Konieczka JH, Jayaram M, Voziyanov Y. Evolution of variants of yeast site-specific recombinase Flp that utilize native genomic sequences as recombination target sites. Nucleic Acids Research. 34: 5259-69. PMID 17003057 DOI: 10.1093/Nar/Gkl548 |
0.405 |
|
| 2006 |
Hajra S, Ghosh SK, Jayaram M. The centromere-specific histone variant Cse4p (CENP-A) is essential for functional chromatin architecture at the yeast 2-microm circle partitioning locus and promotes equal plasmid segregation. The Journal of Cell Biology. 174: 779-90. PMID 16966420 DOI: 10.1083/Jcb.200603042 |
0.491 |
|
| 2006 |
Ghosh SK, Hajra S, Paek A, Jayaram M. Mechanisms for chromosome and plasmid segregation. Annual Review of Biochemistry. 75: 211-41. PMID 16756491 DOI: 10.1146/Annurev.Biochem.75.101304.124037 |
0.528 |
|
| 2006 |
Mehta S, Yang XM, Jayaram M, Velmurugan S. Erratum: A novel role for the mitotic spindle during DNA segregation in yeast: Promoting 2μm Plasmid-Cohesin Association (Molecular and Cellular Biology (2005) 25, 10 (4283-4298)) Molecular and Cellular Biology. 26. DOI: 10.1128/Mcb.01041-06 |
0.704 |
|
| 2005 |
Dobson MJ, Pickett AJ, Velmurugan S, Pinder JB, Barrett LA, Jayaram M, Chew JS. The 2 microm plasmid causes cell death in Saccharomyces cerevisiae with a mutation in Ulp1 protease. Molecular and Cellular Biology. 25: 4299-310. PMID 15870298 DOI: 10.1128/Mcb.25.10.4299-4310.2005 |
0.415 |
|
| 2005 |
Mehta S, Yang XM, Jayaram M, Velmurugan S. A novel role for the mitotic spindle during DNA segregation in yeast: promoting 2 microm plasmid-cohesin association. Molecular and Cellular Biology. 25: 4283-98. PMID 15870297 DOI: 10.1128/Mcb.25.10.4283-4298.2005 |
0.77 |
|
| 2005 |
Yin Z, Jayaram M, Pathania S, Harshey RM. The Mu transposase interwraps distant DNA sites within a functional transpososome in the absence of DNA supercoiling. The Journal of Biological Chemistry. 280: 6149-56. PMID 15563455 DOI: 10.1074/Jbc.M411679200 |
0.392 |
|
| 2005 |
Voziyanov Y, Grainge I, Jayaram M. Applications of fungal site-specific recombination as a tool in biotechnology and basic biology Applied Mycology and Biotechnology. 5: 189-210. DOI: 10.1016/S1874-5334(05)80010-3 |
0.442 |
|
| 2004 |
Jayaram M, Mehta S, Uzri D, Voziyanov Y, Velmurugan S. Site-specific recombination and partitioning systems in the stable high copy propagation of the 2-micron yeast plasmid. Progress in Nucleic Acid Research and Molecular Biology. 77: 127-72. PMID 15196892 DOI: 10.1016/S0079-6603(04)77004-X |
0.656 |
|
| 2004 |
Yang XM, Mehta S, Uzri D, Jayaram M, Velmurugan S. Mutations in a partitioning protein and altered chromatin structure at the partitioning locus prevent cohesin recruitment by the Saccharomyces cerevisiae plasmid and cause plasmid missegregation. Molecular and Cellular Biology. 24: 5290-303. PMID 15169893 DOI: 10.1128/Mcb.24.12.5290-5303.2004 |
0.764 |
|
| 2004 |
Konieczka JH, Paek A, Jayaram M, Voziyanov Y. Recombination of hybrid target sites by binary combinations of Flp variants: mutations that foster interprotomer collaboration and enlarge substrate tolerance. Journal of Molecular Biology. 339: 365-78. PMID 15136039 DOI: 10.1016/J.Jmb.2004.03.060 |
0.331 |
|
| 2004 |
Jayaram M, Mehta S, Uzri D, Velmurugan S. Segregation of the yeast plasmid: similarities and contrasts with bacterial plasmid partitioning. Plasmid. 51: 162-78. PMID 15109823 DOI: 10.1016/J.Plasmid.2004.02.005 |
0.735 |
|
| 2003 |
Velmurugan S, Mehta S, Jayaram M. Selfishness in moderation: evolutionary success of the yeast plasmid. Current Topics in Developmental Biology. 56: 1-24. PMID 14584724 DOI: 10.1016/S0070-2153(03)01005-6 |
0.718 |
|
| 2003 |
Velmurugan S, Mehta S, Uzri D, Jayaram M. Stable propagation of 'selfish' genetic elements. Journal of Biosciences. 28: 623-36. PMID 14517366 DOI: 10.1007/Bf02703338 |
0.707 |
|
| 2003 |
Pathania S, Jayaram M, Harshey RM. A unique right end-enhancer complex precedes synapsis of Mu ends: the enhancer is sequestered within the transpososome throughout transposition. The Embo Journal. 22: 3725-36. PMID 12853487 DOI: 10.1093/Emboj/Cdg354 |
0.399 |
|
| 2003 |
Voziyanov Y, Konieczka JH, Stewart AF, Jayaram M. Stepwise manipulation of DNA specificity in Flp recombinase: progressively adapting Flp to individual and combinatorial mutations in its target site. Journal of Molecular Biology. 326: 65-76. PMID 12547191 DOI: 10.1016/S0022-2836(02)01364-5 |
0.497 |
|
| 2002 |
Mehta S, Yang XM, Chan CS, Dobson MJ, Jayaram M, Velmurugan S. The 2 micron plasmid purloins the yeast cohesin complex: a mechanism for coupling plasmid partitioning and chromosome segregation? The Journal of Cell Biology. 158: 625-37. PMID 12177044 DOI: 10.1083/Jcb.200204136 |
0.758 |
|
| 2002 |
Grainge I, Pathania S, Vologodskii A, Harshey RM, Jayaram M. Symmetric DNA sites are functionally asymmetric within Flp and Cre site-specific DNA recombination synapses. Journal of Molecular Biology. 320: 515-27. PMID 12096907 DOI: 10.1016/S0022-2836(02)00517-X |
0.494 |
|
| 2002 |
Pathania S, Jayaram M, Harshey RM. Path of DNA within the Mu transpososome. Transposase interactions bridging two Mu ends and the enhancer trap five DNA supercoils. Cell. 109: 425-36. PMID 12086600 DOI: 10.1016/S0092-8674(02)00728-6 |
0.447 |
|
| 2002 |
Voziyanov Y, Stewart AF, Jayaram M. A dual reporter screening system identifies the amino acid at position 82 in Flp site-specific recombinase as a determinant for target specificity. Nucleic Acids Research. 30: 1656-63. PMID 11917027 DOI: 10.1093/Nar/30.7.1656 |
0.412 |
|
| 2001 |
Grainge I, Lee J, Xu CJ, Jayaram M. DNA recombination and RNA cleavage activities of the Flp protein: Roles of two histidine residues in the orientation and activation of the nucleophile for strand cleavage Journal of Molecular Biology. 314: 717-733. PMID 11733992 DOI: 10.1006/Jmbi.2001.5194 |
0.439 |
|
| 2001 |
Sau AK, DeVue Tribble G, Grainge I, Frohlich RF, Knudsen BR, Jayaram M. Biochemical and kinetic analysis of the RNase active sites of the integrase/tyrosine family site-specific DNA recombinases. The Journal of Biological Chemistry. 276: 46612-23. PMID 11585826 DOI: 10.1074/Jbc.M106492200 |
0.427 |
|
| 2001 |
Lisby M, Olesen JR, Skouboe C, Krogh BO, Straub T, Boege F, Velmurugan S, Martensen PM, Andersen AH, Jayaram M, Westergaard O, Knudsen BR. Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation. The Journal of Biological Chemistry. 276: 20220-7. PMID 11283003 DOI: 10.1074/Jbc.M010991200 |
0.389 |
|
| 2001 |
Frøhlich RF, Hansen SG, Lisby M, Grainge I, Westergaard O, Jayaram M, Knudsen BR. Inhibition of Flp recombinase by the topoisomerase I-targeting drugs, camptothecin and NSC-314622. The Journal of Biological Chemistry. 276: 6993-7. PMID 11152668 DOI: 10.1074/Jbc.C000901200 |
0.342 |
|
| 2000 |
Grainge I, Buck D, Jayaram M. Geometry of site alignment during Int family recombination: Antiparallel synapsis by the Flp recombinase Journal of Molecular Biology. 298: 749-764. PMID 10801346 DOI: 10.1006/Jmbi.2000.3679 |
0.44 |
|
| 2000 |
Velmurugan S, Yang XM, Chan CS, Dobson M, Jayaram M. Partitioning of the 2-microm circle plasmid of Saccharomyces cerevisiae. Functional coordination with chromosome segregation and plasmid-encoded rep protein distribution. The Journal of Cell Biology. 149: 553-66. PMID 10791970 DOI: 10.1083/Jcb.149.3.553 |
0.695 |
|
| 2000 |
Tribble G, Ahn YT, Lee J, Dandekar T, Jayaram M. DNA recognition, strand selectivity, and cleavage mode during integrase family site-specific recombination Journal of Biological Chemistry. 275: 22255-22267. PMID 10748094 DOI: 10.1074/Jbc.M908261199 |
0.522 |
|
| 2000 |
Lee J, Tribble G, Jayaram M. Resolution of tethered antiparallel and parallel holliday junctions by the Flp site-specific recombinase Journal of Molecular Biology. 296: 403-419. PMID 10669597 DOI: 10.1006/Jmbi.1999.3472 |
0.485 |
|
| 1999 |
Grainge I, Jayaram M. The integrase family of recombinases: Organization and function of the active site Molecular Microbiology. 33: 449-456. PMID 10577069 DOI: 10.1046/J.1365-2958.1999.01493.X |
0.415 |
|
| 1999 |
Voziyanov Y, Pathania S, Jayaram M. A general model for site-specific recombination by the integrase family recombinases. Nucleic Acids Research. 27: 930-41. PMID 9927723 DOI: 10.1093/Nar/27.4.930 |
0.443 |
|
| 1999 |
Lee J, Jayaram M, Grainge I. Wild-type Flp recombinase cleaves DNA in trans Embo Journal. 18: 784-791. PMID 9927438 DOI: 10.1093/Emboj/18.3.784 |
0.472 |
|
| 1998 |
Velmurugan S, Ahn YT, Yang XM, Wu XL, Jayaram M. The 2 micrometer plasmid stability system: analyses of the interactions among plasmid- and host-encoded components. Molecular and Cellular Biology. 18: 7466-77. PMID 9819432 DOI: 10.1128/Mcb.18.12.7466 |
0.621 |
|
| 1998 |
Xu CJ, Ahn YT, Pathania S, Jayaram M. Flp ribonuclease activities. Mechanistic similarities and contrasts to site-specific DNA recombination. The Journal of Biological Chemistry. 273: 30591-8. PMID 9804830 DOI: 10.1074/Jbc.273.46.30591 |
0.383 |
|
| 1998 |
Knudsen BR, Lee J, Lisby M, Westergaard O, Jayaram M. Alcoholysis and strand joining by the Flp site-specific recombinase: Mechanistically equivalent reactions mediated by distinct catalytic configurations Journal of Biological Chemistry. 273: 22028-22036. PMID 9705345 DOI: 10.1074/Jbc.273.34.22028 |
0.437 |
|
| 1998 |
Xu CJ, Grainge I, Lee J, Harshey RM, Jayaram M. Unveiling two distinct ribonuclease activities and a topoisomerase activity in a site-specific DNA recombinase Molecular Cell. 1: 729-739. PMID 9660956 DOI: 10.1016/S1097-2765(00)80072-6 |
0.439 |
|
| 1998 |
Lee J, Voziyanov Y, Pathania S, Jayaram M. Structural alterations and conformational dynamics in Holliday junctions induced by binding of a site-specific recombinase. Molecular Cell. 1: 483-93. PMID 9660933 DOI: 10.1016/S1097-2765(00)80049-0 |
0.385 |
|
| 1997 |
Ahn YT, Wu XL, Biswal S, Velmurugan S, Volkert FC, Jayaram M. The 2μm-plasmid-encoded Rep1 and Rep2 proteins interact with each other and colocalize to the Saccharomyces cerevisiae nucleus Journal of Bacteriology. 179: 7497-7506. PMID 9393716 DOI: 10.1128/Jb.179.23.7497-7506.1997 |
0.393 |
|
| 1997 |
Lee J, Tonozuka T, Jayaram M. Mechanism of active site exclusion in a site-specific recombinase: Role of the DNA substrate in conferring half-of-the-sites activity Genes and Development. 11: 3061-3071. PMID 9367987 DOI: 10.1101/Gad.11.22.3061 |
0.441 |
|
| 1997 |
Lee J, Jayaram M. A tetramer of the Flp recombinase silences the trimers within it during resolution of a Holliday junction substrate Genes and Development. 11: 2438-2447. PMID 9308970 DOI: 10.1101/Gad.11.18.2438 |
0.481 |
|
| 1997 |
Saxena P, Whang I, Voziyanov Y, Harkey C, Argos P, Jayaram M, Dandekar T. Probing Flp: A new approach to analyze the structure of a DNA recognizing protein by combining the genetic algorithm, mutagenesis and non-canonical DNA target sites Biochimica Et Biophysica Acta - Protein Structure and Molecular Enzymology. 1340: 187-204. PMID 9252106 DOI: 10.1016/S0167-4838(97)00017-4 |
0.463 |
|
| 1997 |
Jayaram M. The cis-trans paradox of integrase Science. 276: 49-51. PMID 9122709 DOI: 10.1126/Science.276.5309.49 |
0.324 |
|
| 1997 |
Knudsen BR, Dahlstrøm K, Westergaard O, Jayaram M. The yeast site-specific recombinase Flp mediates alcoholysis and hydrolysis of the strand cleavage product: Mimicking the strand-joining reaction with non-DNA nucleophiles Journal of Molecular Biology. 266: 93-107. PMID 9054973 DOI: 10.1006/Jmbi.1996.0767 |
0.478 |
|
| 1996 |
Lee J, Whang I, Jayaram M. Assembly and orientation of Flp recombinase active sites on two-, three- and four-armed DNA substrates: Implications for a recombination mechanism Journal of Molecular Biology. 257: 532-549. PMID 8648622 DOI: 10.1006/Jmbi.1996.0183 |
0.505 |
|
| 1996 |
Voziyanov Y, Lee J, Whang I, Jayaram M. Analyses of the first chemical step in Flp site-specific recombination: Synapsis may not be a pre-requisite for strand cleavage Journal of Molecular Biology. 256: 720-735. PMID 8642593 DOI: 10.1006/Jmbi.1996.0120 |
0.506 |
|
| 1996 |
Yang JY, Jayaram M, Harshey RM. Positional information within the MU transposase tetramer: Catalytic contributions of individual monomers Cell. 85: 447-455. PMID 8616899 DOI: 10.1016/S0092-8674(00)81122-8 |
0.412 |
|
| 1995 |
Lee J, Jayaram M. Role of partner homology in DNA recombination: Complementary base pairing orients the 5′-hydroxyl for strand joining during Flp site-specific recombination Journal of Biological Chemistry. 270: 4042-4052. PMID 7876153 DOI: 10.1074/Jbc.270.8.4042 |
0.498 |
|
| 1995 |
Kim K, Namgoong SY, Jayaram M, Harshey RM. Step-arrest mutants of Phage Mu transposase: Implications in DNA-protein assembly, Mu end cleavage, and strand transfer Journal of Biological Chemistry. 270: 1472-1479. PMID 7836417 DOI: 10.1074/Jbc.270.3.1472 |
0.438 |
|
| 1995 |
Yang JY, Kim K, Jayaram M, Harshey RM. A domain sharing model for active site assembly within the Mu A tetramer during transposition: The enhancer may specify domain contributions Embo Journal. 14: 2374-2384. PMID 7774595 DOI: 10.1002/J.1460-2075.1995.Tb07232.X |
0.338 |
|
| 1995 |
Kimball AS, Kimball ML, Jayaram M, Tullius TD. Chemical probe and missing nucleoside analysis of flp recombinase bound to the recombination target sequence Nucleic Acids Research. 23: 3009-3017. PMID 7659525 DOI: 10.1093/Nar/23.15.3009 |
0.467 |
|
| 1995 |
Lee J, Jayaram M. Junction mobility and resolution of holliday structures by Flp site-specific recombinase: Testing partner compatibility during recombination Journal of Biological Chemistry. 270: 19086-19092. PMID 7642573 DOI: 10.1074/Jbc.270.32.19086 |
0.426 |
|
| 1995 |
Yang JY, Jayaram M, Harshey RM. Enhancer-independent variants of phage Mu transposase: Enhancer-specific stimulation of catalytic activity by a partner transposase Genes and Development. 9: 2545-2555. PMID 7590234 DOI: 10.1101/Gad.9.20.2545 |
0.398 |
|
| 1995 |
Lee J, Jayaram M. Functional roles of individual recombinase monomers in strand breakage and strand union during site-specific DNA recombination Journal of Biological Chemistry. 270: 23203-23211. PMID 7559468 DOI: 10.1074/Jbc.270.39.23203 |
0.496 |
|
| 1994 |
Namgoong SY, Jayaram M, Kim K, Harshey RM. DNA-protein cooperativity in the assembly and stabilization of Mu strand transfer complex: Relevance of DNA phasing and att site cleavage Journal of Molecular Biology. 238: 514-527. PMID 8176742 DOI: 10.1006/Jmbi.1994.1311 |
0.502 |
|
| 1994 |
Yang SH, Jayaram M. Generality of the shared active site among yeast family site-specific recombinases. The ARg site-specific recombinase follows the Flp paradigm Journal of Biological Chemistry. 269: 12789-12796. PMID 8175691 |
0.307 |
|
| 1994 |
Jayaram M. Phosphoryl transfer in Flp recombination: a template for strand transfer mechanisms Trends in Biochemical Sciences. 19: 78-82. PMID 8160270 DOI: 10.1016/0968-0004(94)90039-6 |
0.448 |
|
| 1994 |
Lee J, Whang I, Jayaram M. Directed protein replacement in recombination full sites reveals trans-horizontal DNA cleavage by Flp recombinase Embo Journal. 13: 5346-5354. PMID 7957100 DOI: 10.1002/J.1460-2075.1994.Tb06869.X |
0.523 |
|
| 1994 |
Whang I, Lee J, Jayaram M. Active-site assembly and mode of DNA cleavage by Flp recombinase during full-site recombination Molecular and Cellular Biology. 14: 7492-7498. PMID 7935464 DOI: 10.1128/Mcb.14.11.7492 |
0.464 |
|
| 1993 |
Kimball AS, Lee J, Jayaram M, Tullius TD. Sequence-specific cleavage of DNA via nucleophilic attack of hydrogen peroxide, assisted by Flp recombinase Biochemistry. 32: 4698-4701. PMID 8490015 DOI: 10.1021/Bi00069A002 |
0.432 |
|
| 1993 |
Serre MC, Lei-Zheng, Jayaram M. DNA splicing by an active site mutant of Flp recombinase: Possible catalytic cooperativity between the inactive protein and its DNA substrate Journal of Biological Chemistry. 268: 455-463. PMID 8416950 |
0.348 |
|
| 1993 |
Lee J, Jayaram M. Mechanism of site-specific recombination: Logic of assembling recombinase catalytic site from fractional active sites Journal of Biological Chemistry. 268: 17564-17570. PMID 8349636 |
0.375 |
|
| 1993 |
Chen JW, Yang SH, Jayaram M. Tests for the fractional active-site model in Flp site-specific recombination: Assembly of a functional recombination complex in half-site and full-site strand transfer Journal of Biological Chemistry. 268: 14417-14425. PMID 8314800 |
0.325 |
|
| 1993 |
Miyazaki A, Momany M, Szaniszlo PJ, Jayaram M, Ootaki T. Chitin synthase-encoding gene(s) of the Zygomycete fungus Phycomyces blakesleeanus. Gene. 134: 129-34. PMID 8244024 DOI: 10.1016/0378-1119(93)90186-7 |
0.343 |
|
| 1992 |
Serre MC, Jayaram M. Half-site strand transfer by step-arrest mutants of yeast site-specific recombinase Flp Journal of Molecular Biology. 225: 643-649. PMID 1602475 DOI: 10.1016/0022-2836(92)90391-V |
0.415 |
|
| 1992 |
Serre MC, Evans BR, Araki H, Oshima Y, Jayaram M. Half-site recombinations mediated by yeast site-specific recombinases Flp and R. Journal of Molecular Biology. 225: 621-42. PMID 1602474 DOI: 10.1016/0022-2836(92)90390-6 |
0.405 |
|
| 1992 |
Chen JW, Lee J, Jayaram M. DNA cleavage in trans by the active site tyrosine during Flp recombination: Switching protein partners before exchanging strands Cell. 69: 647-658. PMID 1586945 DOI: 10.1016/0092-8674(92)90228-5 |
0.496 |
|
| 1992 |
Araki H, Nakanishi N, Evans BR, Matsuzaki H, Jayaram M, Oshima Y. Site-specific recombinase, R, encoded by yeast plasmid pSR1. Journal of Molecular Biology. 225: 25-37. PMID 1583692 DOI: 10.1016/0022-2836(92)91023-I |
0.418 |
|
| 1992 |
Chen JW, Evans BR, Yang SH, Araki H, Oshima Y, Jayaram M. Functional analysis of box I mutations in yeast site-specific recombinases Flp and R: pairwise complementation with recombinase variants lacking the active-site tyrosine. Molecular and Cellular Biology. 12: 3757-65. PMID 1508181 DOI: 10.1128/Mcb.12.9.3757 |
0.427 |
|
| 1992 |
Lee J, Serre MC, Yang SH, Whang I, Araki H, Oshima Y, Jayaram M. Functional analysis of Box II mutations in yeast site-specific recombinases Flp and R. Significance of amino acid conservation within the Int family and the yeast sub-family Journal of Molecular Biology. 228: 1091-1103. PMID 1474580 DOI: 10.1016/0022-2836(92)90317-D |
0.37 |
|
| 1992 |
Jing-Wen C, Evans B, Rosenfeldt H, Jayaram M. Bending-incompetent variants of Flp recombinase mediate strand transfer in half-site recombinations: role of DNA bending in recombination Gene. 119: 37-48. PMID 1398089 DOI: 10.1016/0378-1119(92)90064-V |
0.492 |
|
| 1991 |
Chen JW, Evans BR, Yang SH, Teplow DB, Jayaram M. Domain of a yeast site-specific recombinase (Flp) that recognizes its target site. Proceedings of the National Academy of Sciences of the United States of America. 88: 5944-8. PMID 2068070 DOI: 10.1073/Pnas.88.14.5944 |
0.418 |
|
| 1991 |
Chen JW, Evans BR, Zheng L, Jayaram M. Tyr60 variants of Flp recombinase generate conformationally altered protein-DNA complexes. Differential activity in full-site and half-site recombinations. Journal of Molecular Biology. 218: 107-18. PMID 2002496 DOI: 10.1016/0022-2836(91)90877-9 |
0.515 |
|
| 1991 |
Kuo CF, Zou A, Jayaram M, Getzoff E, Harshey R. DNA-protein complexes during attachment-site synapsis in Mu DNA transposition Embo Journal. 10: 1585-1591. PMID 1851088 |
0.403 |
|
| 1991 |
Ootaki T, Miyazaki A, Fukui J, Kimura Y, Umemura S, Okazaki R, Jayaram M. A high efficient method for introduction of exogenous genes into Phycomyces blakesleeanus Japanese Journal of Genetics. 66: 189-195. DOI: 10.1266/Jjg.66.189 |
0.347 |
|
| 1991 |
Kuo C, Zou A, Jayaram M, Getzoff E, Harshey R. DNA-protein complexes during attachment-site synapsis in Mu DNA transposition. The Embo Journal. 10: 1585-1591. DOI: 10.1002/J.1460-2075.1991.Tb07679.X |
0.497 |
|
| 1990 |
Parsons RL, Evans BR, Zheng L, Jayaram M. Functional analysis of Arg-308 mutants of Flp recombinase. Possible role of Arg-308 in coupling substrate binding to catalysis. The Journal of Biological Chemistry. 265: 4527-33. PMID 2407737 |
0.373 |
|
| 1988 |
Lebreton B, Prasad PV, Jayaram M, Youderian P. Mutations that improve the binding of yeast FLP recombinase to its substrate Genetics. 118: 393-400. PMID 3284782 DOI: 10.1093/genetics/118.3.393 |
0.328 |
|
| 1988 |
Jayaram M, Crain KL, Parsons RL, Harshey RM. Holliday junctions in FLP recombination: resolution by step-arrest mutants of FLP protein. Proceedings of the National Academy of Sciences of the United States of America. 85: 7902-6. PMID 3054874 DOI: 10.1073/Pnas.85.21.7902 |
0.324 |
|
| 1988 |
Parsons RL, Prasad PV, Harshey RM, Jayaram M. Step-arrest mutants of FLP recombinase: implications for the catalytic mechanism of DNA recombination. Molecular and Cellular Biology. 8: 3303-10. PMID 2974924 DOI: 10.1128/mcb.8.8.3303-3310.1988 |
0.344 |
|
| 1987 |
Prasad PV, Young LJ, Jayaram M. Mutations in the 2-microns circle site-specific recombinase that abolish recombination without affecting substrate recognition. Proceedings of the National Academy of Sciences of the United States of America. 84: 2189-93. PMID 3104911 |
0.396 |
|
| 1987 |
Govind NS, Jayaram M. Rapid localization and characterization of random mutations within the 2 micron circle site-specific recombinase: a general strategy for analysis of protein function. Gene. 51: 31-41. PMID 2885247 DOI: 10.1016/0378-1119(87)90471-9 |
0.418 |
|
| 1986 |
Jayaram M. Association of reciprocal exchange with gene conversion between the repeated segments of 2-μm circle Journal of Molecular Biology. 191: 341-354. PMID 3029381 DOI: 10.1016/0022-2836(86)90131-2 |
0.482 |
|
| 1986 |
Jayaram M. Mating type-like conversion promoted by the 2 micrograms circle site-specific recombinase: implications for the double-strand-gap repair model Molecular and Cellular Biology. 6: 3831-3837. PMID 3025614 DOI: 10.1128/mcb.6.11.3831-3837.1986 |
0.414 |
|
| 1986 |
Jayaram M, Sumida S, Young LJ. Inducible expression of REP1 causes inducible expression of the 2 micron circle stability system. Current Genetics. 11: 85-91. PMID 2834084 DOI: 10.1007/BF00378198 |
0.304 |
|
| 1985 |
Jayaram M, Sutton A, Broach JR. Properties of REP3: A cis-acting locus required for stable propagation of the Saccharomyces cerevisiae plasmid 2μm circle Molecular and Cellular Biology. 5: 2466-2475. PMID 3915543 DOI: 10.1128/mcb.5.9.2466-2475.1985 |
0.397 |
|
| 1985 |
Jayaram M. Two-micrometer circle site-specific recombination: The minimal substrate and the possible role of flanking sequences Proceedings of the National Academy of Sciences of the United States of America. 82: 5875-5879. PMID 3898075 |
0.322 |
|
| 1983 |
Jayaram M, Li YY, Broach JR. The yeast plasmid 2μ circle encodes components required for its high copy propagation Cell. 34: 95-104. PMID 6883512 DOI: 10.1016/0092-8674(83)90139-3 |
0.46 |
|
| 1983 |
Broach JR, Li YY, Feldman J, Jayaram M, Abraham J, Nasmyth KA, Hicks JB. Localization and sequence analysis of yeast origins of DNA replication. Cold Spring Harbor Symposia On Quantitative Biology. 47: 1165-73. PMID 6345070 DOI: 10.1101/Sqb.1983.047.01.132 |
0.329 |
|
| 1983 |
Jayaram M, Broach JR. Yeast plasmide 2-μm circle promotes recombination within bacterial transposon Tn5 Proceedings of the National Academy of Sciences of the United States of America. 80: 7264-7268. PMID 6316350 DOI: 10.1073/Pnas.80.23.7264 |
0.393 |
|
| 1982 |
Broach JR, Guarascio VR, Jayaram M. Recombination within the yeast plasmid 2μ circle is site-specific Cell. 29: 227-234. PMID 6286142 DOI: 10.1016/0092-8674(82)90107-6 |
0.462 |
|
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