Joel Pachter - Publications

Affiliations: 
Pharmacology  University of Connecticut Health Center, Farmington, CT, United States 

64 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2014 Shrestha B, Paul D, Pachter JS. Alterations in tight junction protein and IgG permeability accompany leukocyte extravasation across the choroid plexus during neuroinflammation. Journal of Neuropathology and Experimental Neurology. 73: 1047-61. PMID 25289890 DOI: 10.1097/NEN.0000000000000127  1
2014 Wang X, Kimbrel EA, Ijichi K, Paul D, Lazorchak AS, Chu J, Kouris NA, Yavanian GJ, Lu SJ, Pachter JS, Crocker SJ, Lanza R, Xu RH. Human ESC-derived MSCs outperform bone marrow MSCs in the treatment of an EAE model of multiple sclerosis. Stem Cell Reports. 3: 115-30. PMID 25068126 DOI: 10.1016/j.stemcr.2014.04.020  1
2014 Shrestha B, Ge S, Pachter JS. Resolution of central nervous system astrocytic and endothelial sources of CCL2 gene expression during evolving neuroinflammation. Fluids and Barriers of the Cns. 11: 6. PMID 24589378 DOI: 10.1186/2045-8118-11-6  1
2014 Paul D, Ge S, Lemire Y, Jellison ER, Serwanski DR, Ruddle NH, Pachter JS. Cell-selective knockout and 3D confocal image analysis reveals separate roles for astrocyte-and endothelial-derived CCL2 in neuroinflammation. Journal of Neuroinflammation. 11: 10. PMID 24444311 DOI: 10.1186/1742-2094-11-10  1
2014 Kooij G, Kroon J, Paul D, Reijerkerk A, Geerts D, van der Pol SM, van Het Hof B, Drexhage JA, van Vliet SJ, Hekking LH, van Buul JD, Pachter JS, de Vries HE. P-glycoprotein regulates trafficking of CD8(+) T cells to the brain parenchyma. Acta Neuropathologica. 127: 699-711. PMID 24429546 DOI: 10.1007/s00401-014-1244-8  1
2014 Severini C, Passeri PP, Ciotti M, Florenzano F, Possenti R, Zona C, Di Matteo A, Guglielmotti A, Calissano P, Pachter J, Mercanti D. Bindarit, inhibitor of CCL2 synthesis, protects neurons against amyloid-β-induced toxicity Journal of Alzheimer's Disease. 38: 281-293. PMID 23948942 DOI: 10.3233/JAD-131070  1
2014 Shrestha B, Paul D, Pachter JS. Alterations in Tight Junction Protein and IgG Permeability Accompany Leukocyte Extravasation Across the Choroid Plexus During Neuroinflammation Journal of Neuropathology and Experimental Neurology. DOI: 10.1097/NEN.0000000000000127  1
2013 Paul D, Cowan AE, Ge S, Pachter JS. Novel 3D analysis of Claudin-5 reveals significant endothelial heterogeneity among CNS microvessels. Microvascular Research. 86: 1-10. PMID 23261753 DOI: 10.1016/j.mvr.2012.12.001  1
2012 Ge S, Shrestha B, Paul D, Keating C, Cone R, Guglielmotti A, Pachter JS. The CCL2 synthesis inhibitor bindarit targets cells of the neurovascular unit, and suppresses experimental autoimmune encephalomyelitis. Journal of Neuroinflammation. 9: 171. PMID 22788993 DOI: 10.1186/1742-2094-9-171  1
2012 Demarest TG, Murugesan N, Shrestha B, Pachter JS. Rapid expression profiling of brain microvascular endothelial cells by immuno-laser capture microdissection coupled to TaqMan ® Low Density Array Journal of Neuroscience Methods. 206: 200-204. PMID 22425714 DOI: 10.1016/j.jneumeth.2012.02.023  1
2012 Murugesan N, Demarest TG, Madri JA, Pachter JS. Brain regional angiogenic potential at the neurovascular unit during normal aging. Neurobiology of Aging. 33: 1004.e1-16. PMID 22019053 DOI: 10.1016/j.neurobiolaging.2011.09.022  1
2012 Murugesan N, Paul D, Lemire Y, Shrestha B, Ge S, Pachter JS. Active induction of experimental autoimmune encephalomyelitis by MOG 35-55 peptide immunization is associated with differential responses in separate compartments of the choroid plexus Fluids and Barriers of the Cns. 9. DOI: 10.1186/2045-8118-9-15  1
2011 Murugesan N, Macdonald J, Ge S, Pachter JS. Probing the CNS microvascular endothelium by immune-guided laser-capture microdissection coupled to quantitative RT-PCR. Methods in Molecular Biology (Clifton, N.J.). 755: 385-94. PMID 21761321 DOI: 10.1007/978-1-61779-163-5_32  1
2011 Murugesan N, Macdonald JA, Lu Q, Wu SL, Hancock WS, Pachter JS. Analysis of mouse brain microvascular endothelium using laser capture microdissection coupled with proteomics. Methods in Molecular Biology (Clifton, N.J.). 686: 297-311. PMID 21082378  1
2010 Zeevi N, Pachter J, McCullough LD, Wolfson L, Kuchel GA. The blood-brain barrier: geriatric relevance of a critical brain-body interface. Journal of the American Geriatrics Society. 58: 1749-57. PMID 20863334 DOI: 10.1111/j.1532-5415.2010.03011.x  1
2010 Macdonald JA, Murugesan N, Pachter JS. Endothelial cell heterogeneity of blood-brain barrier gene expression along the cerebral microvasculature Journal of Neuroscience Research. 88: 1457-1474. PMID 20025060 DOI: 10.1002/jnr.22316  1
2009 Ge S, Murugesan N, Pachter JS. Astrocyte-and endothelial-targeted CCL2 conditional knockout mice: Critical tools for studying the pathogenesis of neuroinflammation Journal of Molecular Neuroscience. 39: 269-283. PMID 19340610 DOI: 10.1007/s12031-009-9197-4  1
2008 Macdonald JA, Murugesan N, Pachter JS. Validation of immuno-laser capture microdissection coupled with quantitative RT-PCR to probe blood-brain barrier gene expression in situ Journal of Neuroscience Methods. 174: 219-226. PMID 18692089 DOI: 10.1016/j.jneumeth.2008.07.009  1
2008 Lu Q, Murugesan N, Macdonald JA, Wu SL, Pachter JS, Hancock WS. Analysis of mouse brain microvascular endothelium using immuno-laser capture microdissection coupled to a hybrid linear ion trap with Fourier transform-mass spectrometry proteomics platform Electrophoresis. 29: 2689-2695. PMID 18481836 DOI: 10.1002/elps.200700936  1
2008 Ge S, Song L, Serwanski DR, Kuziel WA, Pachter JS. Transcellular transport of CCL2 across brain microvascular endothelial cells Journal of Neurochemistry. 104: 1219-1232. PMID 18289346 DOI: 10.1111/j.1471-4159.2007.05056.x  1
2007 Niciu MJ, Ma XM, El Meskini R, Pachter JS, Mains RE, Eipper BA. Altered ATP7A expression and other compensatory responses in a murine model of Menkes disease. Neurobiology of Disease. 27: 278-91. PMID 17588765 DOI: 10.1016/j.nbd.2007.05.004  1
2007 Song L, Ge S, Pachter JS. Caveolin-1 regulates expression of junction-associated proteins in brain microvascular endothelial cells Blood. 109: 1515-1523. PMID 17023578 DOI: 10.1182/blood-2006-07-034009  1
2006 Ge S, Pachter JS. Isolation and culture of microvascular endothelial cells from murine spinal cord Journal of Neuroimmunology. 177: 209-214. PMID 16806499 DOI: 10.1016/j.jneuroim.2006.05.012  1
2005 Pachter JS, Song L, Coisne C, Dehouck B. Technical caveats in identifying the source of endothelial cells in cultures derived from brain microvessels (multiple letters) Laboratory Investigation. 85: 1449-1452. PMID 16237457 DOI: 10.1038/labinvest.3700333  1
2005 Kinnecom K, Pachter JS. Selective capture of endothelial and perivascular cells from brain microvessels using laser capture microdissection. Brain Research. Brain Research Protocols. 16: 1-9. PMID 16168706 DOI: 10.1016/j.brainresprot.2005.08.002  1
2005 Dzenko KA, Song L, Ge S, Kuziel WA, Pachter JS. CCR2 expression by brain microvascular endothelial cells is critical for macrophage transendothelial migration in response to CCL2 Microvascular Research. 70: 53-64. PMID 15927208 DOI: 10.1016/j.mvr.2005.04.005  1
2005 Ge S, Song L, Pachter JS. Where is the blood-brain barrier ... Really? Journal of Neuroscience Research. 79: 421-427. PMID 15635601 DOI: 10.1002/jnr.20313  1
2004 Song L, Pachter JS. Monocyte chemoattractant protein-1 alters expression of tight junction-associated proteins in brain microvascular endothelial cells Microvascular Research. 67: 78-89. PMID 14709405 DOI: 10.1016/j.mvr.2003.07.001  1
2004 Ge S, Pachter JS. Caveolin-I Knockdown by Small Interfering RNA Suppresses Responses to the Chemokine Monocyte Chemoattractant Protein-1 by Human Astrocytes Journal of Biological Chemistry. 279: 6688-6695. PMID 14660607 DOI: 10.1074/jbc.M311769200  1
2003 Song L, Pachter JS. Culture of murine brain microvascular endothelial cells that maintain expression and cytoskeletal association of tight junction-associated proteins In Vitro Cellular and Developmental Biology - Animal. 39: 313-320. PMID 14613336 DOI: 10.1290/1543-706X(2003)039<0313:COMBME>2.0.CO;2  1
2003 Pachter JS, De Vries HE, Fabry Z. The blood-brain barrier and its role in immune privilege in the central nervous system Journal of Neuropathology and Experimental Neurology. 62: 593-604. PMID 12834104  1
2002 Andjelkovic AV, Song L, Dzenko KA, Cong H, Pachter JS. Functional expression of CCR2 by human fetal astrocytes Journal of Neuroscience Research. 70: 219-231. PMID 12271471 DOI: 10.1002/jnr.10372  1
2001 Dzenko KA, Andjelkovic AV, Kuziel WA, Pachter JS. The chemokine receptor CCR2 mediates the binding and internalization of monocyte chemoattractant protein-1 along brain microvessels Journal of Neuroscience. 21: 9214-9223. PMID 11717355  1
2001 Andjelkovic AV, Zochowski MR, Morgan F, Pachter JS. Qualitative and quantitative analysis of monocyte transendothelial migration by confocal microscopy and three-dimensional image reconstruction. In Vitro Cellular & Developmental Biology. Animal. 37: 111-20. PMID 11332736 DOI: 10.1290/1071-2690(2001)037<0111:QAQAOM>2.0.CO;2  1
2000 Andjelkovic AV, Kerkovich D, Pachter JS. Monocyte: Astrocyte interactions regulate MCP-1 expression in both cell types Journal of Leukocyte Biology. 68: 545-552. PMID 11037977  1
2000 Andjelkovic AV, Pachter JS. Characterization of binding sites for chemokines MCP-1 and MIP-1α on human brain microvessels Journal of Neurochemistry. 75: 1898-1906. PMID 11032879 DOI: 10.1046/j.1471-4159.2000.0751898.x  1
2000 Akiyama H, Barger S, Barnum S, Bradt B, Bauer J, Cole GM, Cooper NR, Eikelenboom P, Emmerling M, Fiebich BL, Finch CE, Frautschy S, Griffin WS, Hampel H, Hull M, ... ... Pachter J, et al. Inflammation and Alzheimer's disease. Neurobiology of Aging. 21: 383-421. PMID 10858586 DOI: 10.1016/S0197-4580(00)00124-X  1
2000 Antic A, Dzenko KA, Pachter JS. Engagement of the scavenger receptor is not responsible for β-amyloid stimulation of monocytes to a neurocytopathic state Experimental Neurology. 161: 96-101. PMID 10683276 DOI: 10.1006/exnr.1999.7265  1
2000 Weltzien RB, Pachter JS. Visualization of beta-amyloid peptide (Aβ) phagocytosis by human mononuclear phagocytes: Dependency on Aβ aggregate size Journal of Neuroscience Research. 59: 522-527. PMID 10679791 DOI: 10.1002/(SICI)1097-4547(20000215)59:4<522::AID-JNR7>3.0.CO;2-L  1
1999 Andjelkovic AV, Kerkovich D, Shanley J, Pulliam L, Pachter JS. Expression of binding sites for chemokines on human astrocytes Glia. 28: 225-235. PMID 10559781 DOI: 10.1002/(SICI)1098-1136(199912)28:3<225::AID-GLIA6>3.0.CO;2-6  1
1999 Andjelkovic AV, Spencer DD, Pachter JS. Visualization of chemokine binding sites on human brain microvessels. The Journal of Cell Biology. 145: 403-12. PMID 10209033 DOI: 10.1083/jcb.145.2.403  1
1998 Andjelkovic AV, Nikolic B, Pachter JS, Zecevic N. Macrophages/microglial cells in human central nervous system during development: An immunohistochemical study Brain Research. 814: 13-25. PMID 9838024 DOI: 10.1016/S0006-8993(98)00830-0  1
1998 Andjelkovic AV, Pachter JS. Central nervous system endothelium in neuroinflammatory, neuroinfectious, and neurodegenerative disease Journal of Neuroscience Research. 51: 423-430. PMID 9514196 DOI: 10.1002/(SICI)1097-4547(19980215)51:4<423::AID-JNR2>3.0.CO;2-E  1
1997 Dzenko KA, Weltzien RB, Pachter JS. Suppression of Aβ-induced monocyte neurotoxicity by antiinflammatory compounds Journal of Neuroimmunology. 80: 6-12. PMID 9413254 DOI: 10.1016/S0165-5728(97)00128-8  1
1997 Pachter JS. Inflammatory mechanisms in Alzheimer disease: The role of beta-amyloid/glial interactions Molecular Psychiatry. 2: 91-95. PMID 9106224  1
1997 Bhandari V, Lu H, Pachter J, Kresch MJ. Actin depolymerization is developmentally regulated in rat type II cells exposed to terbutaline Pediatric Research. 41: 166-171. PMID 9029633  1
1996 Shanley JD, Biegel D, Pachter JS. A rapid and sensitive radioimmunoassay for the detection of human cytomegalovirus binding and infection of human fibroblasts Journal of Virological Methods. 58: 121-129. PMID 8783157 DOI: 10.1016/0166-0934(95)02000-4  1
1996 London JA, Biegel D, Pachter JS. Neurocytopathic effects of β-amyloid-stimulated monocytes: A potential mechanism for central nervous system damage in Alzheimer disease Proceedings of the National Academy of Sciences of the United States of America. 93: 4147-4152. PMID 8633031 DOI: 10.1073/pnas.93.9.4147  1
1996 Biegel D, Pachter JS. Adhesion of monocytic and astroglial cells: Effects of inflammatory mediators Neuroscience Research Communications. 18: 47-55. DOI: 10.1002/(SICI)1520-6769(199601)18:1<47::AID-NRC139>3.0.CO;2-9  1
1995 Biegel D, Spencer DD, Pachter JS. Isolation and culture of human brain microvessel endothelial cells for the study of blood-brain barrier properties in vitro. Brain Research. 692: 183-9. PMID 8548302 DOI: 10.1016/0006-8993(95)00511-N  1
1994 Biegel D, Pachter JS. Growth of brain microvessel endothelial cells on collagen gels: Applications to the study of blood-brain barrier physiology and CNS inflammation In Vitro Cellular and Developmental Biology - Animal. 30: 581-588. PMID 7820308 DOI: 10.1007/BF02631256  1
1993 Sharpless K, Biegel D, Yang T, Pachter JS. β-Actin mRNA-binding proteins associated with the cytoskeletal framework European Journal of Biochemistry. 212: 217-225. PMID 8444157  1
1992 Biegel D, Pachter JS. mRNA association with cytoskeletal framework likely represents a physiological binding event Journal of Cellular Biochemistry. 48: 98-106. PMID 1583074  1
1992 Pachter JS. Association of mRNA with the cytoskeletal framework: Its role in the regulation of gene expression Critical Reviews in Eukaryotic Gene Expression. 2: 1-18. PMID 1543896  1
1991 Biegel D, Pachter JS. 'In situ' translation: Use of the cytoskeletal framework to direct cell-free protein synthesis In Vitro Cellular and Developmental Biology - Animal. 27: 75-85. PMID 2013556  1
1988 Yen TJ, Gay DA, Pachter JS, Cleveland DW. Autoregulated changes in stability of polyribosome-bound beta-tubulin mRNAs are specified by the first 13 translated nucleotides Molecular and Cellular Biology. 8: 1224-1235. PMID 2835666  1
1987 Napolitano EW, Pachter JS, Liem RK. Intracellular distribution of mammalian stress proteins. Effects of cytoskeletal-specific agents. The Journal of Biological Chemistry. 262: 1493-504. PMID 2879839  1
1987 Pachter JS, Yen TJ, Cleveland DW. Autoregulation of tubulin expression is achieved through specific degradation of polysomal tubulin mRNAs Cell. 51: 283-292. PMID 2444342 DOI: 10.1016/0092-8674(87)90155-3  1
1985 Napolitano EW, Pachter JS, Chin SS, Liem RK. beta-Internexin, a ubiquitous intermediate filament-associated protein. The Journal of Cell Biology. 101: 1323-31. PMID 3900089  1
1985 Liem RK, Pachter JS, Napolitano EW, Chin SS, Moraru E, Heimann R. Associated proteins as possible cross-linkers in the neuronal cytoskeleton. Annals of the New York Academy of Sciences. 455: 492-508. PMID 2417528  1
1985 Pachter JS, Liem RK. alpha-Internexin, a 66-kD intermediate filament-binding protein from mammalian central nervous tissues. The Journal of Cell Biology. 101: 1316-22. PMID 2413040  1
1984 Pachter JS, Liem RK. The differential appearance of neurofilament triplet polypeptides in the developing rat optic nerve. Developmental Biology. 103: 200-10. PMID 6425096 DOI: 10.1016/0012-1606(84)90021-6  1
1983 Tokutake S, Hutchison SB, Pachter JS, Liem RK. A batchwise purification procedure of neurofilament proteins. Analytical Biochemistry. 135: 102-5. PMID 6322610 DOI: 10.1016/0003-2697(83)90736-4  1
1979 Miller BL, Pachter JS, Valzelli L. Brain tryptophan in isolated aggressive mice Neuropsychobiology. 5: 11-15. PMID 571054  1
Show low-probability matches.