Jay Rappaport - Publications

Affiliations: 
Biomedical Neuroscience Temple University, Philadelphia, PA, United States 
Area:
Neuroscience Biology, Molecular Biology, Virology Biology

90 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann SE, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, ... ... Rappaport J, et al. The Impact of SIV-Induced Immunodeficiency on SARS-CoV-2 Disease, Viral Dynamics, and Antiviral Immune Response in a Nonhuman Primate Model of Coinfection. Viruses. 16. PMID 39066335 DOI: 10.3390/v16071173  0.403
2024 Thirugnanam S, Wang C, Zheng C, Grasperge BF, Datta PK, Rappaport J, Qin X, Rout N. High IL-1β and IL-18 Levels Associate with Gut Barrier Disruption and Monocyte Activation During Chronic SIV Infection with Long-Term Suppressive Antiretroviral Therapy. Biorxiv : the Preprint Server For Biology. PMID 38948748 DOI: 10.1101/2024.06.14.599106  0.304
2023 Melton A, Rowe LA, Penney T, Krzykwa C, Goff K, Scheuermann S, Melton HJ, Williams K, Golden N, Green KM, Smith B, Russell-Lodrigue K, Dufour JP, Doyle-Meyers LA, Schiro F, ... ... Rappaport J, et al. The Impact of SIV-Induced Immunodeficiency on Clinical Manifestation, Immune Response, and Viral Dynamics in SARS-CoV-2 Coinfection. Biorxiv : the Preprint Server For Biology. PMID 38014096 DOI: 10.1101/2023.11.15.567132  0.361
2023 Thirugnanam S, Walker EM, Schiro F, Aye PP, Rappaport J, Rout N. Enhanced IL-17 Producing and Maintained Cytolytic Effector Functions of Gut Mucosal CD161CD8 T Cells in SIV-Infected Rhesus Macaques. Viruses. 15. PMID 37766350 DOI: 10.3390/v15091944  0.423
2021 Spitsin S, Pappa V, Kinder A, Evans DL, Rappaport J, Douglas SD. Effect of aprepitant on kynurenine to tryptophan ratio in cART treated and cART naïve adults living with HIV. Medicine. 100: e25313. PMID 34114978 DOI: 10.1097/MD.0000000000025313  0.413
2020 Vakili S, Fischer T, Rappaport J. M2 differentiation of MonoMac-1 cell line induced by M-CSF and glucocorticoid pathways. Journal of Cellular Physiology. PMID 32052452 DOI: 10.1002/Jcp.29638  0.423
2019 Kearns AC, Velasquez S, Liu F, Dai S, Chen Y, Lehmicke G, Gordon J, Rappaport J, Qin X. Elevated indoleamine-2,3-dioxygenase enzyme activity in a novel mouse model of HIV-associated atherosclerosis. Aids (London, England). 33: 1557-1564. PMID 31306164 DOI: 10.1097/Qad.0000000000002255  0.527
2017 Spector SA, Rappaport J. HIV cure strategists: ignore the central nervous system at your patients' peril. Aids (London, England). 31: 167-168. PMID 27898594 DOI: 10.1097/Qad.0000000000001268  0.523
2016 Cornwell WD, Wagner W, Lewis MG, Fan X, Rappaport J, Rogers TJ. Effect of chronic morphine administration on circulating dendritic cells in SIV-infected rhesus macaques. Journal of Neuroimmunology. 295: 30-40. PMID 27235346 DOI: 10.1016/J.Jneuroim.2016.04.007  0.306
2015 Rappaport J, Volsky DJ. Role of the macrophage in HIV-associated neurocognitive disorders and other comorbidities in patients on effective antiretroviral treatment. Journal of Neurovirology. 21: 235-41. PMID 25933548 DOI: 10.1007/S13365-015-0346-Y  0.569
2015 Rappaport J, Volsky DJ. Role of the macrophage in HIV-associated neurocognitive disorders and other comorbidities in patients on effective antiretroviral treatment Journal of Neurovirology. DOI: 10.1007/s13365-015-0346-y  0.392
2014 Rappaport J. Editorial: the monocyte/macrophage in the pathogenesis of AIDS: the next frontier for therapeutic intervention in the CNS and beyond: part I. Current Hiv Research. 12: 75-6. PMID 25088181 DOI: 10.2174/1570162X1202140725100102  0.313
2014 Fischer T, Wyatt CM, D'Agati VD, Croul S, McCourt L, Morgello S, Rappaport J. Mononuclear phagocyte accumulation in visceral tissue in HIV encephalitis: evidence for increased monocyte/macrophage trafficking and altered differentiation. Current Hiv Research. 12: 201-12. PMID 25026899 DOI: 10.2174/1570162X12666140713165141  0.572
2014 Pitcher J, Abt A, Myers J, Han R, Snyder M, Graziano A, Festa L, Kutzler M, Garcia F, Gao WJ, Fischer-Smith T, Rappaport J, Meucci O. Neuronal ferritin heavy chain and drug abuse affect HIV-associated cognitive dysfunction. The Journal of Clinical Investigation. 124: 656-69. PMID 24401274 DOI: 10.1172/Jci70090  0.773
2013 Cornwell WD, Lewis MG, Fan X, Rappaport J, Rogers TJ. Effect of chronic morphine administration on circulating T cell population dynamics in rhesus macaques. Journal of Neuroimmunology. 265: 43-50. PMID 24090653 DOI: 10.1016/J.Jneuroim.2013.09.013  0.351
2013 Kogan M, Deshmane S, Sawaya BE, Gracely EJ, Khalili K, Rappaport J. Inhibition of NF-κB activity by HIV-1 Vpr is dependent on Vpr binding protein. Journal of Cellular Physiology. 228: 781-90. PMID 23001849 DOI: 10.1002/Jcp.24226  0.621
2012 Kogan M, Fischer-Smith T, Kaminsky R, Lehmicke G, Rappaport J. CSF-1R up-regulation is associated with response to pharmacotherapy targeting tyrosine kinase activity in AML cell lines. Anticancer Research. 32: 893-9. PMID 22399609  0.739
2012 Kogan M, Haine V, Ke Y, Wigdahl B, Fischer-Smith T, Rappaport J. Macrophage colony stimulating factor regulation by nuclear factor kappa B: a relevant pathway in human immunodeficiency virus type 1 infected macrophages. Dna and Cell Biology. 31: 280-9. PMID 21895511 DOI: 10.1089/Dna.2011.1357  0.793
2011 Kogan M, Rappaport J. HIV-1 accessory protein Vpr: relevance in the pathogenesis of HIV and potential for therapeutic intervention. Retrovirology. 8: 25. PMID 21489275 DOI: 10.1186/1742-4690-8-25  0.719
2010 Rom I, Darbinyan A, White MK, Rappaport J, Sawaya BE, Amini S, Khalili K. Activation of HIV-1 LTR by Rad51 in microglial cells. Cell Cycle (Georgetown, Tex.). 9: 3715-22. PMID 20890127 DOI: 10.4161/Cc.9.18.12930  0.538
2010 Rappaport J, Berger JR. Genetic testing and HIV dementia: teasing out the molecular mechanisms of disease. Aids (London, England). 24: 1585-7. PMID 20523202 DOI: 10.1097/Qad.0B013E32833Ac7E8  0.442
2010 Fischer-Smith T, Rappaport J. HIV Co-receptors: The brain perspective Chemokine Receptors and Neuroaids: Beyond Co-Receptor Function and Links to Other Neuropathologies. 33-50. DOI: 10.1007/978-1-4419-0793-6_3  0.783
2009 Stettner MR, Nance JA, Wright CA, Kinoshita Y, Kim WK, Morgello S, Rappaport J, Khalili K, Gordon J, Johnson EM. SMAD proteins of oligodendroglial cells regulate transcription of JC virus early and late genes coordinately with the Tat protein of human immunodeficiency virus type 1. The Journal of General Virology. 90: 2005-14. PMID 19420158 DOI: 10.1099/Vir.0.011072-0  0.469
2009 Deshmane SL, Mukerjee R, Fan S, Del Valle L, Michiels C, Sweet T, Rom I, Khalili K, Rappaport J, Amini S, Sawaya BE. Activation of the oxidative stress pathway by HIV-1 Vpr leads to induction of hypoxia-inducible factor 1alpha expression. The Journal of Biological Chemistry. 284: 11364-73. PMID 19204000 DOI: 10.1074/Jbc.M809266200  0.483
2008 Fischer-Smith T, Bell C, Croul S, Lewis M, Rappaport J. Monocyte/macrophage trafficking in acquired immunodeficiency syndrome encephalitis: lessons from human and nonhuman primate studies. Journal of Neurovirology. 14: 318-26. PMID 18780233 DOI: 10.1080/13550280802132857  0.825
2008 Fischer-Smith T, Tedaldi EM, Rappaport J. CD163/CD16 coexpression by circulating monocytes/macrophages in HIV: potential biomarkers for HIV infection and AIDS progression. Aids Research and Human Retroviruses. 24: 417-21. PMID 18373432 DOI: 10.1089/Aid.2007.0193  0.804
2008 Sahaf B, Atkuri K, Heydari K, Malipatlolla M, Rappaport J, Regulier E, Herzenberg LA, Herzenberg LA. Culturing of human peripheral blood cells reveals unsuspected lymphocyte responses relevant to HIV disease. Proceedings of the National Academy of Sciences of the United States of America. 105: 5111-6. PMID 18364393 DOI: 10.1073/Pnas.0712363105  0.549
2008 Kaminski R, Darbinian N, Sawaya BE, Slonina D, Amini S, Johnson EM, Rappaport J, Khalili K, Darbinyan A. Puralpha as a cellular co-factor of Rev/RRE-mediated expression of HIV-1 intron-containing mRNA. Journal of Cellular Biochemistry. 103: 1231-45. PMID 17722108 DOI: 10.1002/Jcb.21503  0.433
2008 Sahaf B, Atkuri K, Heydari K, Rappaport J, Herzenberg LA, Herzenberg LA. Tat Protein Enables HIV Infection of PBMC at Physiological Oxygen Levels The Faseb Journal. 22: 508-508. DOI: 10.1096/Fasebj.22.2_Supplement.508  0.497
2007 Mueller YM, Petrovas C, Do DH, Altork SR, Fischer-Smith T, Rappaport J, Altman JD, Lewis MG, Katsikis PD. Early establishment and antigen dependence of simian immunodeficiency virus-specific CD8+ T-cell defects. Journal of Virology. 81: 10861-8. PMID 17670818 DOI: 10.1128/Jvi.00813-07  0.813
2007 Fischer-Smith T, Croul S, Bell C, Lewis M, Rappaport J. Alterations in CD163+/CD16+ monocytes/macrophages in CNS and blood in HIV-1 and SIV associated CNS disease Journal of Neuropathology and Experimental Neurology. 66: 458. DOI: 10.1097/01.Jnen.0000268977.83663.B8  0.807
2006 Haine V, Fischer-Smith T, Rappaport J. Macrophage colony-stimulating factor in the pathogenesis of HIV infection: potential target for therapeutic intervention. Journal of Neuroimmune Pharmacology : the Official Journal of the Society On Neuroimmune Pharmacology. 1: 32-40. PMID 18040789 DOI: 10.1007/S11481-005-9003-1  0.824
2006 Datta PK, Rappaport J. HIV and complement: hijacking an immune defense. Biomedicine & Pharmacotherapy = Biomã©Decine & Pharmacothã©Rapie. 60: 561-8. PMID 16978830 DOI: 10.1016/J.Biopha.2006.07.087  0.538
2006 Kaniowska D, Kaminski R, Amini S, Radhakrishnan S, Rappaport J, Johnson E, Khalili K, Del Valle L, Darbinyan A. Cross-interaction between JC virus agnoprotein and human immunodeficiency virus type 1 (HIV-1) Tat modulates transcription of the HIV-1 long terminal repeat in glial cells. Journal of Virology. 80: 9288-99. PMID 16940540 DOI: 10.1128/Jvi.02138-05  0.587
2006 Darbinian-Sarkissian N, Czernik M, Peruzzi F, Gordon J, Rappaport J, Reiss K, Khalili K, Amini S. Dysregulation of NGF-signaling and Egr-1 expression by Tat in neuronal cell culture. Journal of Cellular Physiology. 208: 506-15. PMID 16741963 DOI: 10.1002/Jcp.20675  0.352
2006 Devadas K, Boykins RA, Hardegen NJ, Philp D, Kleinman HK, Osa EO, Wang J, Clouse KA, Wahl LM, Hewlett IK, Rappaport J, Yamada KM, Dhawan S. Selective side-chain modification of cysteine and arginine residues blocks pathogenic activity of HIV-1-Tat functional peptides. Peptides. 27: 611-21. PMID 16256245 DOI: 10.1016/J.Peptides.2005.09.013  0.514
2006 Darbinian-Sarkissian N, Darbinyan A, Otte J, Radhakrishnan S, Sawaya BE, Arzumanyan A, Chipitsyna G, Popov Y, Rappaport J, Amini S, Khalili K. p27(SJ), a novel protein in St John's Wort, that suppresses expression of HIV-1 genome. Gene Therapy. 13: 288-95. PMID 16251997 DOI: 10.1038/Sj.Gt.3302649  0.541
2005 Fischer-Smith T, Rappaport J. Evolving paradigms in the pathogenesis of HIV-1-associated dementia. Expert Reviews in Molecular Medicine. 7: 1-26. PMID 16321172 DOI: 10.1017/S1462399405010239  0.822
2005 Diop G, Spadoni JL, Do H, Hirtzig T, Coulonges C, Labib T, Issing W, Rappaport J, Therwath A, Lathrop M, Matsuda F, Zagury JF. Genomic approach of AIDS pathogenesis: exhaustive genotyping of the TNFR1 gene in a French AIDS cohort. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 59: 474-80. PMID 16153798 DOI: 10.1016/J.Biopha.2005.07.011  0.468
2005 Régulier EG, Panemangalore R, Richardson MW, DeFranco JJ, Kocieda V, Gordon-Lyles DC, Silvera P, Khalili K, Zagury JF, Lewis MG, Rappaport J. Persistent anti-gag, -Nef, and -Rev IgM levels as markers of the impaired functions of CD4+ T-helper lymphocytes during SIVmac251 infection of cynomolgus macaques. Journal of Acquired Immune Deficiency Syndromes (1999). 40: 1-11. PMID 16123674 DOI: 10.1097/01.Qai.0000173702.05308.C4  0.416
2005 Peruzzi F, Bergonzini V, Aprea S, Reiss K, Sawaya BE, Rappaport J, Amini S, Khalili K. Cross talk between growth factors and viral and cellular factors alters neuronal signaling pathways: implication for HIV-associated dementia. Brain Research. Brain Research Reviews. 50: 114-25. PMID 15936090 DOI: 10.1016/J.Brainresrev.2005.05.002  0.527
2005 Abbas A, Vasilescu A, Do H, Hendel H, Maachi M, Goutalier FX, Regulier EG, Rappaport J, Matsuda F, Therwath A, Aucouturier P, Zagury JF. Analysis of IGG and IGG4 in HIV-1 seropositive patients and correlation with biological and genetic markers. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 59: 38-46. PMID 15740934 DOI: 10.1016/J.Biopha.2004.07.001  0.384
2005 Abraham S, Sweet T, Sawaya BE, Rappaport J, Khalili K, Amini S. Cooperative interaction of C/EBP beta and Tat modulates MCP-1 gene transcription in astrocytes. Journal of Neuroimmunology. 160: 219-27. PMID 15710476 DOI: 10.1016/J.Jneuroim.2004.11.009  0.346
2005 Do H, Vasilescu A, Diop G, Hirtzig T, Heath SC, Coulonges C, Rappaport J, Therwath A, Lathrop M, Matsuda F, Zagury JF. Exhaustive genotyping of the CEM15 (APOBEC3G) gene and absence of association with AIDS progression in a French cohort. The Journal of Infectious Diseases. 191: 159-63. PMID 15609224 DOI: 10.1086/426826  0.452
2004 Daniel DC, Kinoshita Y, Khan MA, Del Valle L, Khalili K, Rappaport J, Johnson EM. Internalization of exogenous human immunodeficiency virus-1 protein, Tat, by KG-1 oligodendroglioma cells followed by stimulation of DNA replication initiated at the JC virus origin. Dna and Cell Biology. 23: 858-67. PMID 15684713 DOI: 10.1089/Dna.2004.23.858  0.571
2004 Winkler CA, Hendel H, Carrington M, Smith MW, Nelson GW, O'brien SJ, Phair J, Vlahov D, Jacobson LP, Rappaport J, Vasilescu A, Bertin-Maghit S, An P, Lu W, Andrieu JM, et al. Dominant effects of CCR2-CCR5 haplotypes in HIV-1 disease progression. Journal of Acquired Immune Deficiency Syndromes (1999). 37: 1534-8. PMID 15602133 DOI: 10.1097/01.Qai.0000127353.01578.63  0.47
2004 Fischer-Smith T, Croul S, Adeniyi A, Rybicka K, Morgello S, Khalili K, Rappaport J. Macrophage/microglial accumulation and proliferating cell nuclear antigen expression in the central nervous system in human immunodeficiency virus encephalopathy. The American Journal of Pathology. 164: 2089-99. PMID 15161643 DOI: 10.1016/S0002-9440(10)63767-4  0.829
2004 Vasilescu A, Heath SC, Diop G, Do H, Hirtzig T, Hendel H, Bertin-Maghit S, Rappaport J, Therwath A, Lathrop GM, Matsuda F, Zagury JF. Genomic analysis of Fas and FasL genes and absence of correlation with disease progression in AIDS. Immunogenetics. 56: 56-60. PMID 15042330 DOI: 10.1007/S00251-004-0664-3  0.452
2004 Richardson MW, Sverstiuk AE, Silvera P, Greenhouse J, Lisziewicz J, Lori F, Khalili K, Lewis MG, Rappaport J. T-cell receptor excision circles (TREC) in SHIV 89.6p and SIVmac251 models of HIV-1 infection. Dna and Cell Biology. 23: 1-13. PMID 14965468 DOI: 10.1089/104454904322745880  0.475
2004 Régulier EG, Reiss K, Khalili K, Amini S, Zagury JF, Katsikis PD, Rappaport J. T-cell and neuronal apoptosis in HIV infection: implications for therapeutic intervention. International Reviews of Immunology. 23: 25-59. PMID 14690854 DOI: 10.1080/08830180490265538  0.493
2004 Rappaport J, Fischer-Smith T, Croul S, Adeniyi A, Rybicka K, Morgello S, Khalili K. Role of perivascular macrophages trafficking in HIV associated dementia complex Journal of Neurovirology. 10: 38-38. DOI: 10.1080/13550280490469815  0.823
2003 Richardson MW, Sverstiuk AE, Gracely EJ, Hendel H, Khalili K, Zagury JF, Rappaport J. T-cell receptor excision circles (TREC) and maintenance of long-term non-progression status in HIV-1 infection. Aids (London, England). 17: 915-7. PMID 12660540 DOI: 10.1097/00002030-200304110-00018  0.411
2003 Richardson MW, Mirchandani J, Duong J, Grimaldo S, Kocieda V, Hendel H, Khalili K, Zagury JF, Rappaport J. Antibodies to Tat and Vpr in the GRIV cohort: differential association with maintenance of long-term non-progression status in HIV-1 infection. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 57: 4-14. PMID 12642031 DOI: 10.1016/S0753-3322(02)00327-X  0.404
2003 Rappaport J. Perspectives in HIV pathogenesis, treatment, and prevention. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 57: 1-3. PMID 12642030 DOI: 10.1016/S0753-3322(02)00002-1  0.515
2003 Ying Wang J, Peruzzi F, Lassak A, Del Valle L, Radhakrishnan S, Rappaport J, Khalili K, Amini S, Reiss K. Neuroprotective effects of IGF-I against TNFalpha-induced neuronal damage in HIV-associated dementia. Virology. 305: 66-76. PMID 12504542 DOI: 10.1006/Viro.2002.1690  0.524
2002 Richardson MW, Mirchandani J, Silvera P, Régulier EG, Capini C, Bojczuk PM, Hu J, Gracely EJ, Boyer JD, Khalili K, Zagury JF, Lewis MG, Rappaport J. Immunogenicity of HIV-1 IIIB and SHIV 89.6P Tat and Tat toxoids in rhesus macaques: induction of humoral and cellular immune responses. Dna and Cell Biology. 21: 637-51. PMID 12396606 DOI: 10.1089/104454902760330174  0.448
2002 Silvera P, Richardson MW, Greenhouse J, Yalley-Ogunro J, Shaw N, Mirchandani J, Khalili K, Zagury JF, Lewis MG, Rappaport J. Outcome of simian-human immunodeficiency virus strain 89.6p challenge following vaccination of rhesus macaques with human immunodeficiency virus Tat protein. Journal of Virology. 76: 3800-9. PMID 11907220 DOI: 10.1128/Jvi.76.8.3800-3809.2002  0.473
2002 Schwartz EJ, Neumann AU, Teixeira AV, Bruggeman LA, Rappaport J, Perelson AS, Klotman PE. Effect of target cell availability on HIV-1 production in vitro. Aids (London, England). 16: 341-5. PMID 11834944 DOI: 10.1097/00002030-200202150-00004  0.472
2001 Fischer-Smith T, Croul S, Sverstiuk AE, Capini C, L'Heureux D, Régulier EG, Richardson MW, Amini S, Morgello S, Khalili K, Rappaport J. CNS invasion by CD14+/CD16+ peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection. Journal of Neurovirology. 7: 528-41. PMID 11704885 DOI: 10.1080/135502801753248114  0.82
2001 Daniel DC, Wortman MJ, Schiller RJ, Liu H, Gan L, Mellen JS, Chang CF, Gallia GL, Rappaport J, Khalili K, Johnson EM. Coordinate effects of human immunodeficiency virus type 1 protein Tat and cellular protein Puralpha on DNA replication initiated at the JC virus origin. The Journal of General Virology. 82: 1543-53. PMID 11413364 DOI: 10.1099/0022-1317-82-7-1543  0.425
2001 Hendel H, Winkler C, An P, Roemer-Binns E, Nelson G, Haumont P, O'Brien S, Khalilli K, Zagury D, Rappaport J, Zagury JF. Validation of genetic case-control studies in AIDS and application to the CX3CR1 polymorphism. Journal of Acquired Immune Deficiency Syndromes (1999). 26: 507-11. PMID 11391174 DOI: 10.1097/00126334-200104150-00019  0.303
2001 Capini CJ, Richardson MW, Hendel H, Sverstiuk A, Mirchandani J, Régulier EG, Khalili K, Zagury JF, Rappaport J. Autoantibodies to TNFalpha in HIV-1 infection: prospects for anti-cytokine vaccine therapy. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 55: 23-31. PMID 11237281 DOI: 10.1016/S0753-3322(00)00018-4  0.547
2000 Del Valle L, Croul S, Morgello S, Amini S, Rappaport J, Khalili K. Detection of HIV-1 Tat and JCV capsid protein, VP1, in AIDS brain with progressive multifocal leukoencephalopathy. Journal of Neurovirology. 6: 221-8. PMID 10878711 DOI: 10.3109/13550280009015824  0.586
2000 Sawaya BE, Khalili K, Gordon J, Srinivasan A, Richardson M, Rappaport J, Amini S. Transdominant activity of human immunodeficiency virus type 1 Vpr with a mutation at residue R73. Journal of Virology. 74: 4877-81. PMID 10775627 DOI: 10.1128/Jvi.74.10.4877-4881.2000  0.33
2000 Richardson MW, Sverstiuk A, Hendel H, Cheung TW, Zagury JF, Rappaport J. Analysis of telomere length and thymic output in fast and slow/non-progressors with HIV infection. Biomedicine & Pharmacotherapy = BioméDecine & PharmacothéRapie. 54: 21-31. PMID 10721459 DOI: 10.1016/S0753-3322(00)88637-0  0.464
1999 Bonwetsch R, Croul S, Richardson MW, Lorenzana C, Del Valle L, Sverstiuk AE, Amini S, Morgello S, Khalili K, Rappaport J. Role of HIV-1 Tat and CC chemokine MIP-1alpha in the pathogenesis of HIV associated central nervous system disorders. Journal of Neurovirology. 5: 685-94. PMID 10602409 DOI: 10.3109/13550289909021297  0.561
1999 Sawaya BE, Khalili K, Rappaport J, Serio D, Chen W, Srinivasan A, Amini S. Suppression of HIV-1 transcription and replication by a Vpr mutant. Gene Therapy. 6: 947-50. PMID 10505122 DOI: 10.1038/Sj.Gt.3300907  0.44
1999 Gallia GL, Darbinian N, Tretiakova A, Ansari SA, Rappaport J, Brady J, Wortman MJ, Johnson EM, Khalili K. Association of HIV-1 Tat with the cellular protein, Puralpha, is mediated by RNA. Proceedings of the National Academy of Sciences of the United States of America. 96: 11572-7. PMID 10500218 DOI: 10.1073/Pnas.96.20.11572  0.483
1999 Rappaport J, Joseph J, Croul S, Alexander G, Del Valle L, Amini S, Khalili K. Molecular pathway involved in HIV-1-induced CNS pathology: role of viral regulatory protein, Tat. Journal of Leukocyte Biology. 65: 458-65. PMID 10204574 DOI: 10.1002/Jlb.65.4.458  0.58
1999 Gringeri A, Santagostino E, Muça-Perja M, Le Buanec H, Bizzini B, Lachgar A, Zagury JF, Rappaport J, Burny A, Gallo RC, Zagury D. Tat toxoid as a component of a preventive vaccine in seronegative subjects. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 20: 371-5. PMID 10096581 DOI: 10.1097/00042560-199904010-00007  0.414
1999 Valle LD, Lippa C, Rappaport J, Amini S, Alexander G, Khalili K, Croul S. MICROGLIA, ASTROCYTES AND OLIGODENDROCYTES EXPRESS HIV- TAT IN CENTRAL NERVOUS SYSTEM AIDS LESIONS Journal of Neuropathology and Experimental Neurology. 58: 527. DOI: 10.1097/00005072-199905000-00084  0.477
1998 Lachgar A, Jaureguiberry G, Le Buenac H, Bizzini B, Zagury JF, Rappaport J, Zagury D. Binding of HIV-1 to RBCs involves the Duffy Antigen Receptors for Chemokines (DARC) Biomedicine and Pharmacotherapy. 52: 436-439. PMID 9921412 DOI: 10.1016/S0753-3322(99)80021-3  0.46
1998 Le Buanec H, Lachgar A, Bizzini B, Zagury JF, Rappaport J, Santagostino E, Muça-Perja M, Gringeri A. A prophylactic and therapeutic AIDS vaccine containing as a component the innocuous Tat Toxoid Biomedicine and Pharmacotherapy. 52: 431-435. PMID 9921411 DOI: 10.1016/S0753-3322(99)80020-1  0.419
1998 Baier-Bitterlich G, Tretiakova A, Richardson MW, Khalili K, Jameson B, Rappaport J. Structure and function of HIV-1 and SIV Tat proteins based on carboxy- terminal truncations, chimeric Tat constructs, and NMR modeling Biomedicine and Pharmacotherapy. 52: 421-430. PMID 9921410 DOI: 10.1016/S0753-3322(99)80019-5  0.521
1998 Hendel H, Hénon N, Lebuanec H, Lachgar A, Poncelet H, Caillat-Zucman S, Winkler CA, Smith MW, Kenefic L, O'Brien S, Lu W, Andrieu JM, Zagury D, Schächter F, Rappaport J, et al. Distinctive effects of CCR5, CCR2, and SDF1 genetic polymorphisms in AIDS progression. Journal of Acquired Immune Deficiency Syndromes and Human Retrovirology : Official Publication of the International Retrovirology Association. 19: 381-6. PMID 9833747 DOI: 10.1097/00042560-199812010-00009  0.454
1998 Kundu M, Sharma S, De Luca A, Giordano A, Rappaport J, Khalili K, Amini S. HIV-1 Tat elongates the G1 phase and indirectly promotes HIV-1 gene expression in cells of glial origin. The Journal of Biological Chemistry. 273: 8130-6. PMID 9525916 DOI: 10.1074/Jbc.273.14.8130  0.519
1998 Zagury D, Lachgar A, Chams V, Fall LS, Bernard J, Zagury JF, Bizzini B, Gringeri A, Santagostino E, Rappaport J, Feldman M, O'Brien SJ, Burny A, Gallo RC. C-C chemokines, pivotal in protection against HIV type 1 infection. Proceedings of the National Academy of Sciences of the United States of America. 95: 3857-61. PMID 9520457 DOI: 10.1073/Pnas.95.7.3857  0.561
1998 Zagury D, Lachgar A, Chams V, Fall LS, Bernard J, Zagury JF, Bizzini B, Gringeri A, Santagostino E, Rappaport J, Feldman M, Burny A, Gallo RC. Interferon alpha and Tat involvement in the immunosuppression of uninfected T cells and C-C chemokine decline in AIDS. Proceedings of the National Academy of Sciences of the United States of America. 95: 3851-6. PMID 9520456 DOI: 10.1073/Pnas.95.7.3851  0.532
1997 Cho YY, Astgen A, Hendel H, Issing W, Perrot JY, Schachter F, Rappaport J, Zagury JF. Homeostasis of chemokines, interferon production and lymphocyte subsets: implications for AIDS pathogenesis. Biomedicine & Pharmacotherapy = Biomedecine & Pharmacotherapie. 51: 221-9. PMID 9247020 DOI: 10.1016/S0753-3322(97)81600-9  0.321
1997 Rappaport J, Cho YY, Hendel H, Schwartz EJ, Schachter F, Zagury JF. 32 bp CCR-5 gene deletion and resistance to fast progression in HIV-1 infected heterozygotes. Lancet (London, England). 349: 922-3. PMID 9093257 DOI: 10.1016/S0140-6736(05)62697-9  0.497
1996 Hendel H, Cho YY, Gauthier N, Rappaport J, Schächter F, Zagury JF. Contribution of cohort studies in understanding HIV pathogenesis: Introduction of the GRIV cohort and preliminary results Biomedicine and Pharmacotherapy. 50: 480-487. PMID 9091061 DOI: 10.1016/S0753-3322(97)89278-5  0.559
1995 Rappaport J, Richardson MW, Klotman PE, Arya SK, Baier-Bitterlich G. Inhibition of HIV-1 expression by HIV-2 Journal of Molecular Medicine. 73: 583-589. PMID 8825754 DOI: 10.1007/BF00196351  0.492
1995 Klotman PE, Rappaport J, Ray P, Kopp JB, Franks R, Bruggeman LA, Notkins AL. Transgenic models of HIV-1 Aids. 9: 313-324. PMID 7794536 DOI: 10.1097/00002030-199504000-00001  0.464
1995 Reddy TR, Suhasini M, Rappaport J, Looney DJ, Kraus G, Wong-Staal F. Molecular cloning and characterization of a TAR-binding nuclear factor from T cells. Aids Research and Human Retroviruses. 11: 663-9. PMID 7576925 DOI: 10.1089/Aid.1995.11.663  0.619
1992 Ojwang JO, Hampel A, Looney DJ, Wong-Staal F, Rappaport J. Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozyme. Proceedings of the National Academy of Sciences of the United States of America. 89: 10802-6. PMID 1438280 DOI: 10.1073/Pnas.89.22.10802  0.621
1992 Taylor J, Pomerantz R, Bagasra O, Chowdhury M, Rappaport J, Khalili K, Amini S. TAR-independent transactivation by Tat in cells derived from the CNS: a novel mechanism of HIV-1 gene regulation. The Embo Journal. 11: 3395-3403. DOI: 10.1002/J.1460-2075.1992.Tb05418.X  0.494
1991 Weeks BS, Klotman ME, Dhawan S, Kibbey M, Rappaport J, Kleinman HK, Yamada KM, Klotman PE. HIV-1 infection of human T lymphocytes results in enhanced α5β1 integrin expression Journal of Cell Biology. 114: 847-853. PMID 1831204 DOI: 10.1083/jcb.114.4.847  0.418
1990 Tada H, Rappaport J, Lashgari M, Amini S, Wong-Staal F, Khalili K. Trans-activation of the JC virus late promoter by the tat protein of type 1 human immunodeficiency virus in glial cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 3479-83. PMID 2159152 DOI: 10.1073/Pnas.87.9.3479  0.712
1989 Ensoli B, Lusso P, Schachter F, Josephs S, Rappaport J, Negro F, Gallo R, Wong-Staal F. Human herpes virus-6 increases HIV-1 expression in co-infected T cells via nuclear factors binding to the HIV-1 enhancer. The Embo Journal. 8: 3019-3027. DOI: 10.1002/j.1460-2075.1989.tb08452.x  0.494
1988 Sadaie MR, Rappaport J, Benter T, Josephs SF, Willis R, Wong-Staal F. Missense mutations in an infectious human immunodeficiency viral genome: Functional mapping of tat and identification of the rev splice acceptor Proceedings of the National Academy of Sciences of the United States of America. 85: 9224-9228. PMID 3194421 DOI: 10.1073/pnas.85.23.9224  0.515
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