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Francisco Barros - Publications

Affiliations: 
Biochemistry and molecular Biology Universidad de Oviedo, Spain, Oviedo, Principado de Asturias, Spain 
Area:
Ion channels
Website:
http://www.uniovi.es/vicinves/web_vieja/unidades/gruposInv/DptoBioquimica/Receptores/main.htm
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48 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Fernández-Villabrille S, Álvarez-González E, Barros F, de la Peña P, Sierra LM. Influence of Kv11.1 (hERG1) K channel expression on DNA damage induced by the genotoxic agent methyl methanesulfonate. Pflugers Archiv : European Journal of Physiology. 473: 197-217. PMID 33452554 DOI: 10.1007/s00424-021-02517-2  0.8
2020 Barros F, de la Peña P, Domínguez P, Sierra LM, Pardo LA. The EAG Voltage-Dependent K Channel Subfamily: Similarities and Differences in Structural Organization and Gating. Frontiers in Pharmacology. 11: 411. PMID 32351384 DOI: 10.3389/Fphar.2020.00411  0.814
2019 Barros F, Pardo LA, Domínguez P, Sierra LM, de la Peña P. New Structures and Gating of Voltage-Dependent Potassium (Kv) Channels and Their Relatives: A Multi-Domain and Dynamic Question. International Journal of Molecular Sciences. 20. PMID 30634573 DOI: 10.3390/Ijms20020248  0.815
2018 Barros F, Domínguez P, de la Peña P. Relative positioning of Kv11.1 (hERG) K channel cytoplasmic domain-located fluorescent tags toward the plasma membrane. Scientific Reports. 8: 15494. PMID 30341381 DOI: 10.1038/S41598-018-33492-X  0.811
2018 de la Peña P, Domínguez P, Barros F. Functional characterization of Kv11.1 (hERG) potassium channels split in the voltage-sensing domain. Pflugers Archiv : European Journal of Physiology. PMID 29572566 DOI: 10.1007/S00424-018-2135-Y  0.814
2017 de la Peña P, Domínguez P, Barros F. Gating mechanism of Kv11.1 (hERG) K+ channels without covalent connection between voltage sensor and pore domains. Pflugers Archiv : European Journal of Physiology. PMID 29270671 DOI: 10.1007/S00424-017-2093-9  0.817
2016 González-Montelongo R, Barros F, Alvarez de la Rosa D, Giraldez T. Plasma membrane insertion of epithelial sodium channels occurs with dual kinetics. Pflugers Archiv : European Journal of Physiology. PMID 26876388 DOI: 10.1007/S00424-016-1799-4  0.794
2015 Carretero L, Llavona P, López-Hernández A, Casado P, Cutillas PR, de la Peña P, Barros F, Domínguez P. ERK and RSK are necessary for TRH-induced inhibition of r-ERG potassium currents in rat pituitary GH3 cells. Cellular Signalling. 27: 1720-30. PMID 26022182 DOI: 10.1016/J.Cellsig.2015.05.014  0.793
2015 Lörinczi É, Gómez-Posada JC, de la Peña P, Tomczak AP, Fernández-Trillo J, Leipscher U, Stühmer W, Barros F, Pardo LA. Voltage-dependent gating of KCNH potassium channels lacking a covalent link between voltage-sensing and pore domains. Nature Communications. 6: 6672. PMID 25818916 DOI: 10.1038/Ncomms7672  0.813
2015 de la Peña P, Machín A, Fernández-Trillo J, Domínguez P, Barros F. Interactions between the N-terminal tail and the gating machinery of hERG K(+) channels both in closed and open/inactive states. PflüGers Archiv : European Journal of Physiology. 467: 1747-56. PMID 25224286 DOI: 10.1007/S00424-014-1612-1  0.802
2013 de la Peña P, Machín A, Fernández-Trillo J, Domínguez P, Barros F. Mapping of interactions between the N- and C-termini and the channel core in HERG K+ channels. The Biochemical Journal. 451: 463-74. PMID 23418776 DOI: 10.1042/Bj20121717  0.451
2012 Barros F, Domínguez P, de la Peña P. Cytoplasmic domains and voltage-dependent potassium channel gating. Frontiers in Pharmacology. 3: 49. PMID 22470342 DOI: 10.3389/Fphar.2012.00049  0.824
2012 Menéndez ST, Rodrigo JP, Alvarez-Teijeiro S, Villaronga MÁ, Allonca E, Vallina A, Astudillo A, Barros F, Suárez C, García-Pedrero JM. Role of HERG1 potassium channel in both malignant transformation and disease progression in head and neck carcinomas. Modern Pathology : An Official Journal of the United States and Canadian Academy of Pathology, Inc. 25: 1069-78. PMID 22460808 DOI: 10.1016/S0959-8049(12)71433-8  0.32
2012 Carretero L, Barros F, Miranda P, Fernández-Trillo J, Machín A, de la Peña P, Domínguez P. Cell type influences the molecular mechanisms involved in hormonal regulation of ERG K+ channels. Pflã¼Gers Archiv : European Journal of Physiology. 463: 685-702. PMID 22415214 DOI: 10.1007/S00424-012-1094-Y  0.692
2012 Ponsati B, Carreño C, Curto-Reyes V, Valenzuela B, Duart MJ, Van den Nest W, Cauli O, Beltran B, Fernandez J, Borsini F, Caprioli A, Di Serio S, Veretchy M, Baamonde A, Menendez L, ... Barros F, et al. An inhibitor of neuronal exocytosis (DD04107) displays long-lasting in vivo activity against chronic inflammatory and neuropathic pain. The Journal of Pharmacology and Experimental Therapeutics. 341: 634-45. PMID 22393248 DOI: 10.1124/Jpet.111.190678  0.756
2011 Fernández-Trillo J, Barros F, Machín A, Carretero L, Domínguez P, de la Peña P. Molecular determinants of interactions between the N-terminal domain and the transmembrane core that modulate hERG K+ channel gating. Plos One. 6: e24674. PMID 21935437 DOI: 10.1371/Journal.Pone.0024674  0.448
2011 de la Peña P, Alonso-Ron C, Machín A, Fernández-Trillo J, Carretero L, Domínguez P, Barros F. Demonstration of physical proximity between the N terminus and the S4-S5 linker of the human ether-a-go-go-related gene (hERG) potassium channel. The Journal of Biological Chemistry. 286: 19065-75. PMID 21474444 DOI: 10.1074/Jbc.M111.238899  0.472
2009 Alonso-Ron C, Barros F, Manso DG, Gómez-Varela D, Miranda P, Carretero L, Domínguez P, de la Peña P. Participation of HERG channel cytoplasmic structures on regulation by the G protein-coupled TRH receptor. Pflã¼Gers Archiv : European Journal of Physiology. 457: 1237-52. PMID 19002712 DOI: 10.1007/S00424-008-0599-X  0.718
2008 Miranda P, Manso DG, Barros F, Carretero L, Hughes TE, Alonso-Ron C, Domínguez P, de la Peña P. FRET with multiply labeled HERG K(+) channels as a reporter of the in vivo coarse architecture of the cytoplasmic domains. Biochimica Et Biophysica Acta. 1783: 1681-99. PMID 18634834 DOI: 10.1016/J.Bbamcr.2008.06.009  0.795
2008 Alonso-Ron C, de la Peña P, Miranda P, Domínguez P, Barros F. Thermodynamic and kinetic properties of amino-terminal and S4-S5 loop HERG channel mutants under steady-state conditions. Biophysical Journal. 94: 3893-911. PMID 18222997 DOI: 10.1529/Biophysj.107.116731  0.704
2005 Miranda P, Giráldez T, de la Peña P, Manso DG, Alonso-Ron C, Gómez-Varela D, Domínguez P, Barros F. Specificity of TRH receptor coupling to G-proteins for regulation of ERG K+ channels in GH3 rat anterior pituitary cells. The Journal of Physiology. 566: 717-36. PMID 15905217 DOI: 10.1113/Jphysiol.2005.085803  0.806
2003 Miranda P, de la Peña P, Gómez-Varela D, Barros F. Role of BK potassium channels shaping action potentials and the associated [Ca(2+)](i) oscillations in GH(3) rat anterior pituitary cells. Neuroendocrinology. 77: 162-76. PMID 12673050 DOI: 10.1159/000069509  0.711
2003 Gomez-Varela D, Giraldez T, de la Pena P, Dupuy SG, Garcia-Manso D, Barros F. Protein kinase C is necessary for recovery from the thyrotropin-releasing hormone-induced r-ERG current reduction in GH3 rat anterior pituitary cells. The Journal of Physiology. 547: 913-29. PMID 12562894 DOI: 10.1111/J.1469-7793.2003.00913.X  0.777
2003 Gómez-Varela D, Barros F, Viloria CG, Giráldez T, Manso DG, Dupuy SG, Miranda P, de la Peña P. Relevance of the proximal domain in the amino-terminus of HERG channels for regulation by a phospholipase C-coupled hormone receptor. Febs Letters. 535: 125-30. PMID 12560090 DOI: 10.1016/S0014-5793(02)03888-7  0.818
2002 Gómez-Varela D, de la Peña P, García J, Giráldez T, Barros F. Influence of amino-terminal structures on kinetic transitions between several closed and open states in human erg K+ channels. The Journal of Membrane Biology. 187: 117-33. PMID 12029369 DOI: 10.1007/S00232-001-0156-4  0.8
2002 Giráldez T, de la Peña P, Gómez-Varela D, Barros F. Correlation between electrical activity and intracellular Ca2+ oscillations in GH3 rat anterior pituitary cells. Cell Calcium. 31: 65-78. PMID 11969247 DOI: 10.1054/Ceca.2001.0260  0.753
2000 Viloria CG, Barros F, Giráldez T, Gómez-Varela D, de la Peña P. Differential effects of amino-terminal distal and proximal domains in the regulation of human erg K(+) channel gating. Biophysical Journal. 79: 231-46. PMID 10866950 DOI: 10.1016/S0006-3495(00)76286-2  0.809
1998 Barros F, Gomez-Varela D, Viloria CG, Palomero T, Giráldez T, de la Peña P. Modulation of human erg K+ channel gating by activation of a G protein-coupled receptor and protein kinase C. The Journal of Physiology. 511: 333-46. PMID 9706014 DOI: 10.1111/J.1469-7793.1998.333Bh.X  0.822
1998 Palomero T, Barros F, del Camino D, Viloria CG, de la Peña P. A G protein beta gamma dimer-mediated pathway contributes to mitogen-activated protein kinase activation by thyrotropin-releasing hormone receptors in transfected COS-7 cells. Molecular Pharmacology. 53: 613-22. PMID 9547350 DOI: 10.1124/Mol.53.4.613  0.741
1997 Barros F, del Camino D, Pardo LA, Palomero T, Giráldez T, de la Peña P. Demonstration of an inwardly rectifying K+ current component modulated by thyrotropin-releasing hormone and caffeine in GH3 rat anterior pituitary cells. Pflã¼Gers Archiv : European Journal of Physiology. 435: 119-29. PMID 9359911 DOI: 10.1007/S004240050491  0.795
1997 del Camino D, Barros F, Pardo LA, de la Peña P. Altered ligand dissociation rates in thyrotropin-releasing hormone receptors mutated in glutamine 105 of transmembrane helix III. Biochemistry. 36: 3308-18. PMID 9116009 DOI: 10.1021/Bi9622534  0.734
1996 Barros F, del Camino D, Pardo LA, de la Peña P. Caffeine enhancement of electrical activity through direct blockade of inward rectifying K+ currents in GH3 rat anterior pituitary cells. Pflã¼Gers Archiv : European Journal of Physiology. 431: 443-51. PMID 8584440 DOI: 10.1007/Bf02207284  0.784
1995 de la Peña P, del Camino D, Pardo LA, Domínguez P, Barros F. Gs couples thyrotropin-releasing hormone receptors expressed in Xenopus oocytes to phospholipase C. The Journal of Biological Chemistry. 270: 3554-9. PMID 7876090 DOI: 10.1074/Jbc.270.8.3554  0.733
1994 Barros F, Villalobos C, García-Sancho J, del Camino D, de la Peña P. The role of the inwardly rectifying K+ current in resting potential and thyrotropin-releasing-hormone-induced changes in cell excitability of GH3 rat anterior pituitary cells. Pflã¼Gers Archiv : European Journal of Physiology. 426: 221-30. PMID 7514284 DOI: 10.1007/Bf00374775  0.774
1993 Barros F, Mieskes G, del Camino D, de la Peña P. Protein phosphatase 2A reverses inhibition of inward rectifying K+ currents by thyrotropin-releasing hormone in GH3 pituitary cells. Febs Letters. 336: 433-9. PMID 8282106 DOI: 10.1016/0014-5793(93)80851-K  0.773
1992 Delgado LM, de la Peña P, del Camino D, Barros F. Okadaic acid and calyculin A enhance the effect of thyrotropin-releasing hormone on GH3 rat anterior pituitary cells excitability. Febs Letters. 311: 41-5. PMID 1397288 DOI: 10.1016/0014-5793(92)81362-P  0.747
1992 de la Peña P, Delgado LM, del Camino D, Barros F. Cloning and expression of the thyrotropin-releasing hormone receptor from GH3 rat anterior pituitary cells. The Biochemical Journal. 284: 891-9. PMID 1377915 DOI: 10.1042/Bj2840891  0.746
1992 de la Peña P, Delgado LM, del Camino D, Barros F. Two isoforms of the thyrotropin-releasing hormone receptor generated by alternative splicing have indistinguishable functional properties. The Journal of Biological Chemistry. 267: 25703-8. PMID 1334485  0.722
1992 Barros F, Delgado LM, del Camino D, de la Peña P. Characteristics and modulation by thyrotropin-releasing hormone of an inwardly rectifying K+ current in patch-perforated GH3 anterior pituitary cells. Pflã¼Gers Archiv : European Journal of Physiology. 422: 31-9. PMID 1331977 DOI: 10.1007/Bf00381510  0.785
1991 Barros F, Lòpez-Briones LG, Coca-Prados M, Belmonte C. Detection and characterization of ca2+-activated k+ channels in transformed cells of human non-pigmented ciliary epithelium Current Eye Research. 10: 731-738. PMID 1914505 DOI: 10.3109/02713689109013867  0.507
1991 Barros F, Delgado LM, Maciá C, de la Peña P. Effects of hypothalamic peptides on electrical activity and membrane currents of 'patch perforated' clamped GH3 anterior pituitary cells. Febs Letters. 279: 33-7. PMID 1671657 DOI: 10.1016/0014-5793(91)80243-V  0.404
1989 Velasco G, Prieto M, Alvarez-Riera J, Gascòn S, Barros F. Characteristics and regulation of a high conductance anion channel in GBK kidney epithelial cells PflüGers Archiv European Journal of Physiology. 414: 304-310. PMID 2476714 DOI: 10.1007/Bf00584631  0.485
1987 Dominguez P, Velasco G, Barros F, Lazo PS. Intestinal brush border membranes contain regulatory subunits of adenylyl cyclase Proceedings of the National Academy of Sciences of the United States of America. 84: 6965-6969. PMID 3118356 DOI: 10.1073/Pnas.84.20.6965  0.336
1986 Velasco G, Iglesias CF, Dominguez P, Barros F, Gascón S, Lazo PS. Protein kinase C from small intestine epithelial cells Biochemical and Biophysical Research Communications. 139: 875-882. PMID 3768005 DOI: 10.1016/S0006-291X(86)80259-5  0.323
1985 Lazo PS, Barros F, Domínguez P, Rivaya A, Velasco G. Adenylate cyclase from rabbit small intestine: Activation by cholera toxin and interaction with calcium Archives of Biochemistry and Biophysics. 239: 587-594. PMID 4004277 DOI: 10.1016/0003-9861(85)90728-3  0.303
1985 Barros F, Katz GM, Kaczorowski GJ. Calcium currents in GH3 cultured pituitary cells under whole-cell voltage-clamp: Inhibition by voltage-dependent potassium currents Proceedings of the National Academy of Sciences of the United States of America. 82: 1108-1112. PMID 2579386 DOI: 10.1073/Pnas.82.4.1108  0.407
1981 Lazo PS, Barros F, de la Peña P, Ramos S. Ion gradients as candidates for transmembrane signaling Trends in Biochemical Sciences. 6: 83-86. DOI: 10.1016/0968-0004(81)90030-X  0.752
1980 de la Peña P, Barros F, Gascón S, Ramos S, Lazo PS. Primary effects of yeast killer toxin. Biochemical and Biophysical Research Communications. 96: 544-50. PMID 6252887 DOI: 10.1016/0006-291X(80)91390-X  0.312
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