Bernardino Ghetti, MD, University of Pisa - Publications

Affiliations: 
Pathology and Laboratory Medicine Indiana University Medical Center, Indianapolis, IN, United States 
Area:
Alzheimer's and other degenerative brain diseases
Website:
http://pathology.iupui.edu/body.cfm?id=3846

396 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Baiardi S, Rossi M, Mammana A, Appleby BS, Barria MA, Calì I, Gambetti P, Gelpi E, Giese A, Ghetti B, Herms J, Ladogana A, Mikol J, Pal S, Ritchie DL, et al. Phenotypic diversity of genetic Creutzfeldt-Jakob disease: a histo-molecular-based classification. Acta Neuropathologica. PMID 34324063 DOI: 10.1007/s00401-021-02350-y  1
2021 Chen CD, Joseph-Mathurin N, Sinha N, Zhou A, Li Y, Friedrichsen K, McCullough A, Franklin EE, Hornbeck R, Gordon B, Sharma V, Cruchaga C, Goate A, Karch C, McDade E, ... ... Ghetti B, et al. Comparing amyloid-β plaque burden with antemortem PiB PET in autosomal dominant and late-onset Alzheimer disease. Acta Neuropathologica. PMID 34319442 DOI: 10.1007/s00401-021-02342-y  1
2021 Keret O, Staffaroni AM, Ringman JM, Cobigo Y, Goh SM, Wolf A, Allen IE, Salloway S, Chhatwal J, Brickman AM, Reyes-Dumeyer D, Bateman RJ, Benzinger TLS, Morris JC, Ances BM, ... ... Ghetti B, et al. Pattern and degree of individual brain atrophy predicts dementia onset in dominantly inherited Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 13: e12197. PMID 34258377 DOI: 10.1002/dad2.12197  1
2021 Hallinan GI, Hoq MR, Ghosh M, Vago FS, Fernandez A, Garringer HJ, Vidal R, Jiang W, Ghetti B. Structure of Tau filaments in Prion protein amyloidoses. Acta Neuropathologica. PMID 34128081 DOI: 10.1007/s00401-021-02336-w  1
2021 Klingstedt T, Shirani H, Ghetti B, Vidal R, Nilsson P. Thiophene-Based Optical Ligands That Selectively Detect Aβ Pathology in Alzheimer's Disease. Chembiochem : a European Journal of Chemical Biology. PMID 34101954 DOI: 10.1002/cbic.202100199  1
2021 Kumar A, Koistinen NA, Malarte ML, Nennesmo I, Ingelsson M, Ghetti B, Lemoine L, Nordberg A. Astroglial tracer BU99008 detects multiple binding sites in Alzheimer's disease brain. Molecular Psychiatry. PMID 33888872 DOI: 10.1038/s41380-021-01101-5  1
2021 Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Correction to: Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607. Acta Neuropathologica. PMID 33830331 DOI: 10.1007/s00401-021-02303-5  1
2021 Sorrentino S, Ascari R, Maderna E, Catania M, Ghetti B, Tagliavini F, Giaccone G, Di Fede G. Microglial Heterogeneity and Its Potential Role in Driving Phenotypic Diversity of Alzheimer's Disease. International Journal of Molecular Sciences. 22. PMID 33803478 DOI: 10.3390/ijms22052780  1
2021 Shi Y, Murzin AG, Falcon B, Epstein A, Machin J, Tempest P, Newell KL, Vidal R, Garringer HJ, Sahara N, Higuchi M, Ghetti B, Jang MK, Scheres SHW, Goedert M. Cryo-EM structures of tau filaments from Alzheimer's disease with PET ligand APN-1607. Acta Neuropathologica. PMID 33723967 DOI: 10.1007/s00401-021-02294-3  1
2021 Chia R, Sabir MS, Bandres-Ciga S, Saez-Atienzar S, Reynolds RH, Gustavsson E, Walton RL, Ahmed S, Viollet C, Ding J, Makarious MB, Diez-Fairen M, Portley MK, Shah Z, Abramzon Y, ... ... Ghetti B, et al. Genome sequencing analysis identifies new loci associated with Lewy body dementia and provides insights into its genetic architecture. Nature Genetics. PMID 33589841 DOI: 10.1038/s41588-021-00785-3  1
2021 Joseph-Mathurin N, Wang G, Kantarci K, Jack CR, McDade E, Hassenstab J, Blazey TM, Gordon BA, Su Y, Chen G, Massoumzadeh P, Hornbeck RC, Allegri RF, Ances BM, Berman SB, ... ... Ghetti B, et al. Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease. Neurology. PMID 33495373 DOI: 10.1212/WNL.0000000000011542  1
2021 Luckett PH, McCullough A, Gordon BA, Strain J, Flores S, Dincer A, McCarthy J, Kuffner T, Stern A, Meeker KL, Berman SB, Chhatwal JP, Cruchaga C, Fagan AM, Farlow MR, ... ... Ghetti B, et al. Modeling autosomal dominant Alzheimer's disease with machine learning. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 33480178 DOI: 10.1002/alz.12259  1
2021 Goedert M, Spillantini MG, Falcon B, Zhang W, Newell KL, Hasegawa M, Scheres SHW, Ghetti B. Tau Protein and Frontotemporal Dementias. Advances in Experimental Medicine and Biology. 1281: 177-199. PMID 33433876 DOI: 10.1007/978-3-030-51140-1_12  1
2020 Buciuc M, Whitwell JL, Kasanuki K, Graff-Radford J, Machulda MM, Duffy JR, Strand EA, Lowe VJ, Graff-Radford NR, Rush BK, Franczak MB, Flanagan ME, Baker MC, Rademakers R, Ross OA, ... Ghetti BF, et al. Lewy body disease is a contributor to logopenic progressive aphasia phenotype. Annals of Neurology. PMID 33274526 DOI: 10.1002/ana.25979  1
2020 Irimia-Dominguez J, Sun C, Li K, Muhoberac BB, Hallinan GI, Garringer HJ, Ghetti B, Jiang W, Vidal R. Cryo-EM structures and functional characterization of homo- and heteropolymers of human ferritin variants. Scientific Reports. 10: 20666. PMID 33244127 DOI: 10.1038/s41598-020-77717-4  1
2020 Groveman BR, Orrù CD, Hughson AG, Raymond LD, Zanusso G, Ghetti B, Campbell KJ, Safar J, Galasko D, Caughey B. Correction to: Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC. Acta Neuropathologica Communications. 8: 180. PMID 33153488 DOI: 10.1186/s40478-020-01052-y  1
2020 Vermunt L, Dicks E, Wang G, Dincer A, Flores S, Keefe SJ, Berman SB, Cash DM, Chhatwal JP, Cruchaga C, Fox NC, Ghetti B, Graff-Radford NR, Hassenstab J, Karch CM, et al. Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease. Brain Communications. 2: fcaa102. PMID 32954344 DOI: 10.1093/braincomms/fcaa102  1
2020 Luo J, Agboola F, Grant E, Masters CL, Albert MS, Johnson SC, McDade EM, Vöglein J, Fagan AM, Benzinger T, Massoumzadeh P, Hassenstab J, Bateman RJ, Morris JC, Perrin RJ, ... ... Ghetti B, et al. Sequence of Alzheimer disease biomarker changes in cognitively normal adults: A cross-sectional study. Neurology. PMID 32873693 DOI: 10.1212/Wnl.0000000000010747  1
2020 Aschenbrenner AJ, Petros J, McDade E, Wang G, Balota DA, Benzinger TL, Cruchaga C, Goate A, Xiong C, Perrin R, Fagan AM, Graff-Radford N, Ghetti B, Levin J, Weidinger E, et al. Relationships between big-five personality factors and Alzheimer's disease pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia (Amsterdam, Netherlands). 12: e12038. PMID 32587883 DOI: 10.1002/Dad2.12038  1
2020 Schultz SA, Strain JF, Adedokun A, Wang Q, Preische O, Kuhle J, Flores S, Keefe S, Dincer A, Ances BM, Berman SB, Brickman AM, Cash DM, Chhatwal J, Cruchaga C, ... ... Ghetti B, et al. Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease. Neurobiology of Disease. 104960. PMID 32522711 DOI: 10.1016/J.Nbd.2020.104960  1
2020 Abskharon R, Seidler PM, Sawaya MR, Cascio D, Yang TP, Philipp S, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Felgner PL, Nakajima R, Glabe CG, et al. Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease. The Journal of Biological Chemistry. PMID 32493775 DOI: 10.1074/Jbc.Ra120.013638  1
2020 Schweighauser M, Shi Y, Tarutani A, Kametani F, Murzin AG, Ghetti B, Matsubara T, Tomita T, Ando T, Hasegawa K, Murayama S, Yoshida M, Hasegawa M, Scheres SHW, Goedert M. Structures of α-synuclein filaments from multiple system atrophy. Nature. PMID 32461689 DOI: 10.1038/S41586-020-2317-6  1
2020 Morgan SA, Lavenir I, Fan J, Masuda-Suzukake M, Passarella D, DeTure MA, Dickson DW, Ghetti B, Goedert M. α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species. The Journal of Biological Chemistry. PMID 32209651 DOI: 10.1074/Jbc.Ra119.012179  1
2020 Brozzetti L, Sacchetto L, Cecchini MP, Avesani A, Perra D, Bongianni M, Portioli C, Scupoli M, Ghetti B, Monaco S, Buffelli M, Zanusso G. Neurodegeneration-Associated Proteins in Human Olfactory Neurons Collected by Nasal Brushing. Frontiers in Neuroscience. 14: 145. PMID 32194369 DOI: 10.3389/Fnins.2020.00145  1
2020 Metrick MA, Ferreira NDC, Saijo E, Kraus A, Newell K, Zanusso G, Vendruscolo M, Ghetti B, Caughey B. A single ultrasensitive assay for detection and discrimination of tau aggregates of Alzheimer and Pick diseases. Acta Neuropathologica Communications. 8: 22. PMID 32087764 DOI: 10.1186/S40478-020-0887-Z  1
2020 Zhang W, Tarutani A, Newell KL, Murzin AG, Matsubara T, Falcon B, Vidal R, Garringer HJ, Shi Y, Ikeuchi T, Murayama S, Ghetti B, Hasegawa M, Goedert M, Scheres SHW. Novel tau filament fold in corticobasal degeneration. Nature. PMID 32050258 DOI: 10.1038/S41586-020-2043-0  1
2020 Reiman EM, Arboleda-Velasquez JF, Quiroz YT, Huentelman MJ, Beach TG, Caselli RJ, Chen Y, Su Y, Myers AJ, Hardy J, Paul Vonsattel J, Younkin SG, Bennett DA, De Jager PL, Larson EB, ... ... Ghetti BF, et al. Exceptionally low likelihood of Alzheimer's dementia in APOE2 homozygotes from a 5,000-person neuropathological study. Nature Communications. 11: 667. PMID 32015339 DOI: 10.1038/S41467-019-14279-8  1
2020 Aschenbrenner AJ, James BD, McDade E, Wang G, Lim YY, Benzinger TLS, Cruchaga C, Goate A, Xiong C, Perrin R, Buckles V, Allegri R, Berman SB, Chhatwal JP, Fagan A, ... ... Ghetti B, et al. Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN). Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 16: 219-228. PMID 31914221 DOI: 10.1002/Alz.12010  1
2019 Klingstedt T, Ghetti B, Holton JL, Ling H, Nilsson KPR, Goedert M. Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson's disease and multiple system atrophy. Acta Neuropathologica Communications. 7: 193. PMID 31796099 DOI: 10.1186/S40478-019-0840-1  1
2019 Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S, Boxer A, Rojas JC, Galasko D, Kraus A, Rossi M, Newell K, Zanusso G, Grinberg LT, Seeley WW, ... Ghetti B, et al. Correction to: 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathologica. PMID 31748840 DOI: 10.1007/S00401-019-02092-Y  1
2019 Metrick MA, do Carmo Ferreira N, Saijo E, Hughson AG, Kraus A, Orrú C, Miller MW, Zanusso G, Ghetti B, Vendruscolo M, Caughey B. Million-fold sensitivity enhancement in proteopathic seed amplification assays for biospecimens by Hofmeister ion comparisons. Proceedings of the National Academy of Sciences of the United States of America. PMID 31641070 DOI: 10.1073/Pnas.1909322116  1
2019 Saijo E, Metrick MA, Koga S, Parchi P, Litvan I, Spina S, Boxer A, Rojas JC, Galasko D, Kraus A, Rossi M, Newell K, Zanusso G, Grinberg LT, Seeley WW, ... Ghetti B, et al. 4-Repeat tau seeds and templating subtypes as brain and CSF biomarkers of frontotemporal lobar degeneration. Acta Neuropathologica. PMID 31616982 DOI: 10.1007/S00401-019-02080-2  1
2019 Bongianni M, Ladogana A, Capaldi S, Klotz S, Baiardi S, Cagnin A, Perra D, Fiorini M, Poleggi A, Legname G, Cattaruzza T, Janes F, Tabaton M, Ghetti B, Monaco S, et al. α-Synuclein RT-QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies. Annals of Clinical and Translational Neurology. PMID 31599499 DOI: 10.1002/Acn3.50897  1
2019 Seidler PM, Boyer DR, Murray KA, Yang TP, Bentzel M, Sawaya MR, Rosenberg G, Cascio D, Williams CK, Newell KL, Ghetti B, DeTure MA, Dickson DW, Vinters HV, Eisenberg DS. Structure-based inhibitors halt prion-like seeding by Alzheimer's disease- and tauopathy-derived brain tissue samples. The Journal of Biological Chemistry. PMID 31537646 DOI: 10.1074/Jbc.Ra119.009688  1
2019 Lavenir I, Passarella D, Masuda-Suzukake M, Curry A, Holton JL, Ghetti B, Goedert M. Silver staining (Campbell-Switzer) of neuronal α-synuclein assemblies induced by multiple system atrophy and Parkinson's disease brain extracts in transgenic mice. Acta Neuropathologica Communications. 7: 148. PMID 31522685 DOI: 10.1186/S40478-019-0804-5  1
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Ghetti B, et al. Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. PMID 31417202 DOI: 10.1038/s41588-019-0495-7  1
2019 Josephs KA, Mackenzie I, Frosch MP, Bigio EH, Neumann M, Arai T, Dugger BN, Ghetti B, Grossman M, Hasegawa M, Herrup K, Holton J, Jellinger K, Lashley T, McAleese KE, et al. LATE to the PART-y. Brain : a Journal of Neurology. PMID 31359030 DOI: 10.1093/Brain/Awz224  1
2019 Cali CP, Patino M, Tai YK, Ho WY, McLean CA, Morris CM, Seeley WW, Miller BL, Gaig C, Vonsattel JPG, White CL, Roeber S, Kretzschmar H, Troncoso JC, Troakes C, ... ... Ghetti B, et al. C9orf72 intermediate repeats are associated with corticobasal degeneration, increased C9orf72 expression and disruption of autophagy. Acta Neuropathologica. PMID 31327044 DOI: 10.1007/S00401-019-02045-5  1
2019 Gondim DD, Oblak A, Murrell JR, Richardson R, Epperson F, Ross OA, Ghetti B. Diffuse Lewy Body Disease and Alzheimer Disease: Neuropathologic Phenotype Associated With the PSEN1 p.A396T Mutation. Journal of Neuropathology and Experimental Neurology. PMID 31165862 DOI: 10.1093/Jnen/Nlz039  1
2019 Cracco L, Xiao X, Nemani SK, Lavrich J, Cali I, Ghetti B, Notari S, Surewicz WK, Gambetti P. Gerstmann-Sträussler-Scheinker disease revisited: accumulation of covalently-linked multimers of internal prion protein fragments. Acta Neuropathologica Communications. 7: 1. PMID 31142381 DOI: 10.1186/S40478-019-0734-2  1
2019 Vöglein J, Paumier K, Jucker M, Preische O, McDade E, Hassenstab J, Benzinger TL, Noble JM, Berman SB, Graff-Radford NR, Ghetti B, Farlow MR, Chhatwal J, Salloway S, Xiong C, et al. Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease. Brain : a Journal of Neurology. PMID 30897203 DOI: 10.1093/Brain/Awz050  1
2019 Falcon B, Zivanov J, Zhang W, Murzin AG, Garringer HJ, Vidal R, Crowther RA, Newell KL, Ghetti B, Goedert M, Scheres SHW. Novel tau filament fold in chronic traumatic encephalopathy encloses hydrophobic molecules. Nature. PMID 30894745 DOI: 10.1038/S41586-019-1026-5  1
2019 Goedert M, Falcon B, Zhang W, Ghetti B, Scheres SHW. Distinct Conformers of Assembled Tau in Alzheimer's and Pick's Diseases. Cold Spring Harbor Symposia On Quantitative Biology. PMID 30886056 DOI: 10.1101/Sqb.2018.83.037580  1
2019 Kunkle BW, Grenier-Boley B, Sims R, Bis JC, Damotte V, Naj AC, Boland A, Vronskaya M, van der Lee SJ, Amlie-Wolf A, Bellenguez C, Frizatti A, Chouraki V, Martin ER, Sleegers K, ... ... Ghetti B, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing. Nature Genetics. 51: 414-430. PMID 30820047 DOI: 10.1038/s41588-019-0358-2  1
2019 Pottier C, Ren Y, Perkerson RB, Baker M, Jenkins GD, van Blitterswijk M, DeJesus-Hernandez M, van Rooij JGJ, Murray ME, Christopher E, McDonnell SK, Fogarty Z, Batzler A, Tian S, Vicente CT, ... ... Ghetti B, et al. Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD. Acta Neuropathologica. PMID 30739198 DOI: 10.1007/S00401-019-01962-9  1
2019 Pardini M, Huey ED, Spina S, Kreisl WC, Morbelli S, Wassermann EM, Nobili F, Ghetti B, Grafman J. FDG-PET patterns associated with underlying pathology in corticobasal syndrome. Neurology. PMID 30700592 DOI: 10.1212/Wnl.0000000000007038  1
2019 Preische O, Schultz SA, Apel A, Kuhle J, Kaeser SA, Barro C, Gräber S, Kuder-Buletta E, LaFougere C, Laske C, Vöglein J, Levin J, Masters CL, Martins R, Schofield PR, ... ... Ghetti B, et al. Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease. Nature Medicine. PMID 30664784 DOI: 10.1038/S41591-018-0304-3  1
2018 Vöglein J, Noachtar S, McDade E, Quaid KA, Salloway S, Ghetti B, Noble J, Berman S, Chhatwal J, Mori H, Fox N, Allegri R, Masters CL, Buckles V, Ringman JM, et al. Seizures as an early symptom of autosomal dominant Alzheimer's disease. Neurobiology of Aging. 76: 18-23. PMID 30616208 DOI: 10.1016/J.Neurobiolaging.2018.11.022  1
2018 Kraus A, Saijo E, Metrick MA, Newell K, Sigurdson CJ, Zanusso G, Ghetti B, Caughey B. Seeding selectivity and ultrasensitive detection of tau aggregate conformers of Alzheimer disease. Acta Neuropathologica. PMID 30570675 DOI: 10.1007/S00401-018-1947-3  1
2018 Newell K, Paron F, Mompean M, Murrell J, Salis E, Stuani C, Pattee G, Romano M, Laurents D, Ghetti B, Buratti E. Dysregulation of TDP-43 Intracellular Localization and Early-Onset ALS are Associated with a TARDBP S375G Variant. Brain Pathology (Zurich, Switzerland). PMID 30461104 DOI: 10.1111/bpa.12680  1
2018 Risacher SL, Farlow MR, Bateman DR, Epperson F, Tallman EF, Richardson R, Murrell JR, Unverzagt FW, Apostolova LG, Bonnin JM, Ghetti B, Saykin AJ. Detection of tau in Gerstmann-Sträussler-Scheinker disease (PRNP F198S) by [F]Flortaucipir PET. Acta Neuropathologica Communications. 6: 114. PMID 30373672 DOI: 10.1186/S40478-018-0608-Z  1
2018 Falcon B, Zhang W, Schweighauser M, Murzin AG, Vidal R, Garringer HJ, Ghetti B, Scheres SHW, Goedert M. Tau filaments from multiple cases of sporadic and inherited Alzheimer's disease adopt a common fold. Acta Neuropathologica. PMID 30276465 DOI: 10.1007/S00401-018-1914-Z  1
2018 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Fox NN, Graff-Radford NR, Levin J, Danek A, et al. Relationship between physical activity, cognition, and Alzheimer pathology in autosomal dominant Alzheimer's disease. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 30266303 DOI: 10.1016/J.Jalz.2018.06.3059  1
2018 McDade E, Wang G, Gordon BA, Hassenstab J, Benzinger TLS, Buckles V, Fagan AM, Holtzman DM, Cairns NJ, Goate AM, Marcus DS, Morris JC, Paumier K, Xiong C, Allegri R, ... ... Ghetti B, et al. Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease. Neurology. PMID 30217935 DOI: 10.1212/Wnl.0000000000006277  1
2018 Falcon B, Zhang W, Murzin AG, Murshudov G, Garringer HJ, Vidal R, Crowther RA, Ghetti B, Scheres SHW, Goedert M. Structures of filaments from Pick's disease reveal a novel tau protein fold. Nature. PMID 30158706 DOI: 10.1038/S41586-018-0454-Y  1
2018 Brelstaff J, Tolkovsky AM, Ghetti B, Goedert M, Spillantini MG. Living Neurons with Tau Filaments Aberrantly Expose Phosphatidylserine and Are Phagocytosed by Microglia. Cell Reports. 24: 1939-1948.e4. PMID 30134156 DOI: 10.1016/J.Celrep.2018.07.072  1
2018 Karch CM, Hernández D, Wang JC, Marsh J, Hewitt AW, Hsu S, Norton J, Levitch D, Donahue T, Sigurdson W, Ghetti B, Farlow M, Chhatwal J, Berman S, Cruchaga C, et al. Human fibroblast and stem cell resource from the Dominantly Inherited Alzheimer Network. Alzheimer's Research & Therapy. 10: 69. PMID 30045758 DOI: 10.1186/S13195-018-0400-0  1
2018 Ghetti B, Piccardo P, Zanusso G. Dominantly inherited prion protein cerebral amyloidoses - a modern view of Gerstmann-Sträussler-Scheinker. Handbook of Clinical Neurology. 153: 243-269. PMID 29887140 DOI: 10.1016/B978-0-444-63945-5.00014-3  1
2018 Lee S, Zimmerman ME, Narkhede A, Nasrabady SE, Tosto G, Meier IB, Benzinger TLS, Marcus DS, Fagan AM, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, et al. White matter hyperintensities and the mediating role of cerebral amyloid angiopathy in dominantly-inherited Alzheimer's disease. Plos One. 13: e0195838. PMID 29742105 DOI: 10.1371/Journal.Pone.0195838  1
2018 Pottier C, Zhou X, Perkerson RB, Baker M, Jenkins GD, Serie DJ, Ghidoni R, Benussi L, Binetti G, López de Munain A, Zulaica M, Moreno F, Le Ber I, Pasquier F, Hannequin D, ... ... Ghetti B, et al. Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study. The Lancet. Neurology. PMID 29724592 DOI: 10.1016/S1474-4422(18)30126-1  1
2018 Chhatwal JP, Schultz AP, Johnson KA, Hedden T, Jaimes S, Benzinger TLS, Jack C, Ances BM, Ringman JM, Marcus DS, Ghetti B, Farlow MR, Danek A, Levin J, Yakushev I, et al. Preferential degradation of cognitive networks differentiates Alzheimer's disease from ageing. Brain : a Journal of Neurology. PMID 29522171 DOI: 10.1093/Brain/Awy053  1
2018 Di Fede G, Catania M, Maderna E, Ghidoni R, Benussi L, Tonoli E, Giaccone G, Moda F, Paterlini A, Campagnani I, Sorrentino S, Colombo L, Kubis A, Bistaffa E, Ghetti B, et al. Molecular subtypes of Alzheimer's disease. Scientific Reports. 8: 3269. PMID 29459625 DOI: 10.1038/s41598-018-21641-1  1
2018 Groveman BR, Orrù CD, Hughson AG, Raymond LD, Zanusso G, Ghetti B, Campbell KJ, Safar J, Galasko D, Caughey B. Rapid and ultra-sensitive quantitation of disease-associated α-synuclein seeds in brain and cerebrospinal fluid by αSyn RT-QuIC. Acta Neuropathologica Communications. 6: 7. PMID 29422107 DOI: 10.1186/s40478-018-0508-2  1
2018 Taylor LM, McMillan PJ, Liachko NF, Strovas TJ, Ghetti B, Bird TD, Dirk Keene C, Kraemer BC. Pathological phosphorylation of tau and TDP-43 by TTBK1 and TTBK2 drives neurodegeneration. Molecular Neurodegeneration. 13: 7. PMID 29409526 DOI: 10.1186/S13024-018-0237-9  1
2017 Lemoine L, Gillberg PG, Svedberg M, Stepanov V, Jia Z, Huang J, Nag S, Tian H, Ghetti B, Okamura N, Higuchi M, Halldin C, Nordberg A. Comparative binding properties of the tau PET tracers THK5117, THK5351, PBB3, and T807 in postmortem Alzheimer brains. Alzheimer's Research & Therapy. 9: 96. PMID 29229003 DOI: 10.1186/S13195-017-0325-Z  1
2017 Rasmussen J, Mahler J, Beschorner N, Kaeser SA, Häsler LM, Baumann F, Nyström S, Portelius E, Blennow K, Lashley T, Fox NC, Sepulveda-Falla D, Glatzel M, Oblak AL, Ghetti B, et al. Amyloid polymorphisms constitute distinct clouds of conformational variants in different etiological subtypes of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. PMID 29158413 DOI: 10.1073/Pnas.1713215114  1
2017 Eskandari-Sedighi G, Daude N, Gapeshina H, Sanders DW, Kamali-Jamil R, Yang J, Shi B, Wille H, Ghetti B, Diamond MI, Janus C, Westaway D. The CNS in inbred transgenic models of 4-repeat Tauopathy develops consistent tau seeding capacity yet focal and diverse patterns of protein deposition. Molecular Neurodegeneration. 12: 72. PMID 28978354 DOI: 10.1186/S13024-017-0215-7  1
2017 Kinnunen KM, Cash DM, Poole T, Frost C, Benzinger TLS, Ahsan RL, Leung KK, Cardoso MJ, Modat M, Malone IB, Morris JC, Bateman RJ, Marcus DS, Goate A, Salloway S, ... ... Ghetti B, et al. Presymptomatic atrophy in autosomal dominant Alzheimer's disease: A serial MRI study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 28738187 DOI: 10.1016/J.Jalz.2017.06.2268  1
2017 Sims R, van der Lee SJ, Naj AC, Bellenguez C, Badarinarayan N, Jakobsdottir J, Kunkle BW, Boland A, Raybould R, Bis JC, Martin ER, Grenier-Boley B, Heilmann-Heimbach S, Chouraki V, Kuzma AB, ... ... Ghetti B, et al. Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease. Nature Genetics. PMID 28714976 DOI: 10.1038/Ng.3916  1
2017 Fitzpatrick AWP, Falcon B, He S, Murzin AG, Murshudov G, Garringer HJ, Crowther RA, Ghetti B, Goedert M, Scheres SHW. Cryo-EM structures of tau filaments from Alzheimer's disease. Nature. PMID 28678775 DOI: 10.1038/Nature23002  1
2017 Müller S, Preische O, Sohrabi HR, Gräber S, Jucker M, Dietzsch J, Ringman JM, Martins RN, McDade E, Schofield PR, Ghetti B, Rossor M, Graff-Radford NR, Levin J, Galasko D, et al. Decreased body mass index in the preclinical stage of autosomal dominant Alzheimer's disease. Scientific Reports. 7: 1225. PMID 28450713 DOI: 10.1038/S41598-017-01327-W  1
2017 Saijo E, Ghetti B, Zanusso G, Oblak A, Furman JL, Diamond MI, Kraus A, Caughey B. Ultrasensitive and selective detection of 3-repeat tau seeding activity in Pick disease brain and cerebrospinal fluid. Acta Neuropathologica. PMID 28293793 DOI: 10.1007/S00401-017-1692-Z  1
2017 Cracco L, Notari S, Cali I, Sy MS, Chen SG, Cohen ML, Ghetti B, Appleby BS, Zou WQ, Caughey B, Safar JG, Gambetti P. Novel strain properties distinguishing sporadic prion diseases sharing prion protein genotype and prion type. Scientific Reports. 7: 38280. PMID 28091514 DOI: 10.1038/Srep38280  1
2017 McEwan WA, Falcon B, Vaysburd M, Clift D, Oblak AL, Ghetti B, Goedert M, James LC. Cytosolic Fc receptor TRIM21 inhibits seeded tau aggregation. Proceedings of the National Academy of Sciences of the United States of America. PMID 28049840 DOI: 10.1073/Pnas.1607215114  1
2016 Garringer HJ, Sammeta N, Oblak A, Ghetti B, Vidal R. Amyloid and intracellular accumulation of BRI2. Neurobiology of Aging. 52: 90-97. PMID 28131015 DOI: 10.1016/J.Neurobiolaging.2016.12.018  1
2016 Galimberti D, Cioffi SM, Fenoglio C, Serpente M, Oblak AL, Rodriguez-Porcel F, Oldoni E, Hagen MC, Arcaro M, Scarpini E, Ghetti B, Espay AJ. Rapidly progressive primary progressive aphasia and parkinsonism with novel GRN mutation. Movement Disorders : Official Journal of the Movement Disorder Society. PMID 27859661 DOI: 10.1002/Mds.26872  1
2016 Tang M, Ryman DC, McDade E, Jasielec MS, Buckles VD, Cairns NJ, Fagan AM, Goate A, Marcus DS, Xiong C, Allegri RF, Chhatwal JP, Danek A, Farlow MR, Fox NC, ... Ghetti B, et al. Neurological manifestations of autosomal dominant familial Alzheimer's disease: a comparison of the published literature with the Dominantly Inherited Alzheimer Network observational study (DIAN-OBS). The Lancet. Neurology. PMID 27777020 DOI: 10.1016/S1474-4422(16)30229-0  1
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Ghetti B, et al. Correction: Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0163669. PMID 27649320 DOI: 10.1371/journal.pone.0163669  1
2016 Umeh CC, Kalakoti P, Greenberg MK, Notari S, Cohen Y, Gambetti P, Oblak AL, Ghetti B, Mari Z. Clinicopathological Correlates in a PRNP P102L Mutation Carrier with Rapidly Progressing Parkinsonism-dystonia. Movement Disorders Clinical Practice. 3: 355-358. PMID 27617269 DOI: 10.1002/Mdc3.12307  1
2016 Garringer HJ, Irimia JM, Li W, Goodwin CB, Richine B, Acton A, Chan RJ, Peacock M, Muhoberac BB, Ghetti B, Vidal R. Effect of Systemic Iron Overload and a Chelation Therapy in a Mouse Model of the Neurodegenerative Disease Hereditary Ferritinopathy. Plos One. 11: e0161341. PMID 27574973 DOI: 10.1371/Journal.Pone.0161341  1
2016 Liachko NF, Saxton AD, McMillan PJ, Strovas TJ, Currey HN, Taylor LM, Wheeler JM, Oblak AL, Ghetti B, Montine TJ, Keene CD, Raskind MA, Bird TD, Kraemer BC. The phosphatase calcineurin regulates pathological TDP-43 phosphorylation. Acta Neuropathologica. PMID 27473149 DOI: 10.1007/S00401-016-1600-Y  1
2016 Catafau AM, Bullich S, Seibyl JP, Barthel H, Ghetti B, Leverenz J, Ironside JW, Schulz-Schaefer WJ, Hoffmann A, Sabri O. Cerebellar amyloid-beta plaques: How frequent are they, and do they influence 18F-Florbetaben SUVR? Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 27363836 DOI: 10.2967/jnumed.115.171652  1
2016 Deng HX, Shi Y, Yang Y, Ahmeti KB, Miller N, Huang C, Cheng L, Zhai H, Deng S, Nuytemans K, Corbett NJ, Kim MJ, Deng H, Tang B, Yang Z, ... ... Ghetti B, et al. Identification of TMEM230 mutations in familial Parkinson's disease. Nature Genetics. PMID 27270108 DOI: 10.1038/Ng.3589  1
2016 Deters KD, Risacher SL, Yoder KK, Oblak AL, Unverzagt FW, Murrell JR, Epperson F, Tallman EF, Quaid KA, Farlow MR, Saykin AJ, Ghetti B. [(11)C]PiB PET in Gerstmann-Sträussler-Scheinker disease. American Journal of Nuclear Medicine and Molecular Imaging. 6: 84-93. PMID 27069768  1
2016 Lee S, Viqar F, Zimmerman ME, Narkhede A, Tosto G, Benzinger TL, Marcus DS, Fagan AM, Goate A, Fox NC, Cairns NJ, Holtzman DM, Buckles V, Ghetti B, McDade E, et al. White matter hyperintensities are a core feature of Alzheimer's disease: Evidence from the Dominantly Inherited Alzheimer Network. Annals of Neurology. PMID 27016429 DOI: 10.1016/J.Jalz.2015.07.133  1
2016 Su Y, Blazey TM, Owen CJ, Christensen JJ, Friedrichsen K, Joseph-Mathurin N, Wang Q, Hornbeck RC, Ances BM, Snyder AZ, Cash LA, Koeppe RA, Klunk WE, Galasko D, Brickman AM, ... ... Ghetti B, et al. Quantitative Amyloid Imaging in Autosomal Dominant Alzheimer's Disease: Results from the DIAN Study Group. Plos One. 11: e0152082. PMID 27010959 DOI: 10.1371/Journal.Pone.0152082  1
2016 Rodriguez-Porcel F, Lowder L, Rademakers R, Ravenscroft T, Ghetti B, Hagen MC, Espay AJ. Fulminant corticobasal degeneration: Agrypnia excitata in corticobasal syndrome. Neurology. PMID 26873956 DOI: 10.1212/Wnl.0000000000002491  1
2016 Pirisinu L, Di Bari MA, D'Agostino C, Marcon S, Riccardi G, Poleggi A, Cohen ML, Appleby BS, Gambetti P, Ghetti B, Agrimi U, Nonno R. Gerstmann-Sträussler-Scheinker disease subtypes efficiently transmit in bank voles as genuine prion diseases. Scientific Reports. 6: 20443. PMID 26841849 DOI: 10.1038/Srep20443  1
2016 Seibyl J, Catafau AM, Barthel H, Ishii K, Rowe CC, Leverenz JB, Ghetti B, Ironside JW, Takao M, Akatsu H, Murayama S, Bullich S, Mueller A, Koglin N, Schulz-Schaeffer WJ, et al. Impact of training method on the robustness of the visual assessment of 18F-florbetaben PET scans: results from a Phase 3 trial. Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine. PMID 26823561 DOI: 10.2967/jnumed.115.161927  1
2015 Kovacs GG, Ferrer I, Grinberg LT, Alafuzoff I, Attems J, Budka H, Cairns NJ, Crary JF, Duyckaerts C, Ghetti B, Halliday GM, Ironside JW, Love S, Mackenzie IR, Munoz DG, et al. Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy. Acta Neuropathologica. PMID 26659578 DOI: 10.1007/S00401-015-1509-X  1
2015 Orrú CD, Groveman BR, Raymond LD, Hughson AG, Nonno R, Zou W, Ghetti B, Gambetti P, Caughey B. Correction: Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains. Plos Pathogens. 11: e1005117. PMID 26284358 DOI: 10.1371/Journal.Ppat.1005117  1
2015 Wang F, Gordon BA, Ryman DC, Ma S, Xiong C, Hassenstab J, Goate A, Fagan AM, Cairns NJ, Marcus DS, McDade E, Ringman JM, Graff-Radford NR, Ghetti B, Farlow MR, et al. Cerebral amyloidosis associated with cognitive decline in autosomal dominant Alzheimer disease. Neurology. PMID 26245925 DOI: 10.1212/Wnl.0000000000001903  1
2015 Ehrlich M, Hallmann AL, Reinhardt P, Araúzo-Bravo MJ, Korr S, Röpke A, Psathaki OE, Ehling P, Meuth SG, Oblak AL, Murrell JR, Ghetti B, Zaehres H, Schöler HR, Sterneckert J, et al. Distinct Neurodegenerative Changes in an Induced Pluripotent Stem Cell Model of Frontotemporal Dementia Linked to Mutant TAU Protein. Stem Cell Reports. 5: 83-96. PMID 26143746 DOI: 10.1016/J.Stemcr.2015.06.001  1
2015 Lemoine L, Saint-Aubert L, Marutle A, Antoni G, Eriksson JP, Ghetti B, Okamura N, Nennesmo I, Gillberg PG, Nordberg A. Visualization of regional tau deposits using (3)H-THK5117 in Alzheimer brain tissue. Acta Neuropathologica Communications. 3: 40. PMID 26134112 DOI: 10.1186/S40478-015-0220-4  1
2015 Orrú CD, Groveman BR, Raymond LD, Hughson AG, Nonno R, Zou W, Ghetti B, Gambetti P, Caughey B. Bank Vole Prion Protein As an Apparently Universal Substrate for RT-QuIC-Based Detection and Discrimination of Prion Strains. Plos Pathogens. 11: e1004983. PMID 26086786 DOI: 10.1371/Journal.Ppat.1004983  1
2015 Kouri N, Ross OA, Dombroski B, Younkin CS, Serie DJ, Soto-Ortolaza A, Baker M, Finch NC, Yoon H, Kim J, Fujioka S, McLean CA, Ghetti B, Spina S, Cantwell LB, et al. Genome-wide association study of corticobasal degeneration identifies risk variants shared with progressive supranuclear palsy. Nature Communications. 6: 7247. PMID 26077951 DOI: 10.1038/Ncomms8247  1
2015 Cairns NJ, Perrin RJ, Franklin EE, Carter D, Vincent B, Xie M, Bateman RJ, Benzinger T, Friedrichsen K, Brooks WS, Halliday GM, McLean C, Ghetti B, Morris JC, et al. Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN). Neuropathology : Official Journal of the Japanese Society of Neuropathology. PMID 25964057 DOI: 10.1111/Neup.12205  1
2015 Sabri O, Sabbagh MN, Seibyl J, Barthel H, Akatsu H, Ouchi Y, Senda K, Murayama S, Ishii K, Takao M, Beach TG, Rowe CC, Leverenz JB, Ghetti B, Ironside JW, et al. Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer disease: Phase 3 study. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. PMID 25824567 DOI: 10.1016/j.jalz.2015.02.004  1
2015 Kaushal V, Dye R, Pakavathkumar P, Foveau B, Flores J, Hyman B, Ghetti B, Koller BH, LeBlanc AC. Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation. Cell Death and Differentiation. PMID 25744023 DOI: 10.1038/Cdd.2015.16  1
2015 Ringman JM, Liang LJ, Zhou Y, Vangala S, Teng E, Kremen S, Wharton D, Goate A, Marcus DS, Farlow M, Ghetti B, McDade E, Masters CL, Mayeux RP, Rossor M, et al. Early behavioural changes in familial Alzheimer's disease in the Dominantly Inherited Alzheimer Network. Brain : a Journal of Neurology. 138: 1036-45. PMID 25688083 DOI: 10.1093/Brain/Awv004  1
2015 Beecham GW, Dickson DW, Scott WK, Martin ER, Schellenberg G, Nuytemans K, Larson EB, Buxbaum JD, Trojanowski JQ, Van Deerlin VM, Hurtig HI, Mash DC, Beach TG, Troncoso JC, Pletnikova O, ... ... Ghetti B, et al. PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease. Neurology. 84: 972-80. PMID 25663231 DOI: 10.1212/Wnl.0000000000001332  1
2015 Li W, Garringer HJ, Goodwin CB, Richine B, Acton A, VanDuyn N, Muhoberac BB, Irimia-Dominguez J, Chan RJ, Peacock M, Nass R, Ghetti B, Vidal R. Systemic and cerebral iron homeostasis in ferritin knock-out mice. Plos One. 10: e0117435. PMID 25629408 DOI: 10.1371/Journal.Pone.0117435  1
2015 Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Ghetti B, et al. Protective variant for hippocampal atrophy identified by whole exome sequencing. Annals of Neurology. 77: 547-52. PMID 25559091 DOI: 10.1002/Ana.24349  1
2015 Ghetti B, Oblak AL, Boeve BF, Johnson KA, Dickerson BC, Goedert M. Invited review: Frontotemporal dementia caused by microtubule-associated protein tau gene (MAPT) mutations: a chameleon for neuropathology and neuroimaging. Neuropathology and Applied Neurobiology. 41: 24-46. PMID 25556536 DOI: 10.1111/Nan.12213  1
2015 Wang LS, Naj AC, Graham RR, Crane PK, Kunkle BW, Cruchaga C, Murcia JD, Cannon-Albright L, Baldwin CT, Zetterberg H, Blennow K, Kukull WA, Faber KM, Schupf N, Norton MC, ... ... Ghetti B, et al. Rarity of the Alzheimer disease-protective APP A673T variant in the United States. Jama Neurology. 72: 209-16. PMID 25531812 DOI: 10.1001/Jamaneurol.2014.2157  1
2015 Su Y, Blazey TM, Snyder AZ, Raichle ME, Marcus DS, Ances BM, Bateman RJ, Cairns NJ, Aldea P, Cash L, Christensen JJ, Friedrichsen K, Hornbeck RC, Farrar AM, Owen CJ, ... ... Ghetti B, et al. Partial volume correction in quantitative amyloid imaging. Neuroimage. 107: 55-64. PMID 25485714 DOI: 10.1016/J.Neuroimage.2014.11.058  1
2014 Deters KD, Risacher SL, Farlow MR, Unverzagt FW, Kareken DA, Hutchins GD, Yoder KK, Murrell JR, Spina S, Epperson F, Gao S, Saykin AJ, Ghetti B. Cerebral hypometabolism and grey matter density in MAPT intron 10 +3 mutation carriers. American Journal of Neurodegenerative Disease. 3: 103-14. PMID 25628962  1
2014 Liachko NF, McMillan PJ, Strovas TJ, Loomis E, Greenup L, Murrell JR, Ghetti B, Raskind MA, Montine TJ, Bird TD, Leverenz JB, Kraemer BC. The tau tubulin kinases TTBK1/2 promote accumulation of pathological TDP-43. Plos Genetics. 10: e1004803. PMID 25473830 DOI: 10.1371/Journal.Pgen.1004803  1
2014 Ringman JM, Goate A, Masters CL, Cairns NJ, Danek A, Graff-Radford N, Ghetti B, Morris JC. Genetic heterogeneity in Alzheimer disease and implications for treatment strategies. Current Neurology and Neuroscience Reports. 14: 499. PMID 25217249 DOI: 10.1007/S11910-014-0499-8  1
2014 Beecham GW, Hamilton K, Naj AC, Martin ER, Huentelman M, Myers AJ, Corneveaux JJ, Hardy J, Vonsattel JP, Younkin SG, Bennett DA, De Jager PL, Larson EB, Crane PK, Kamboh MI, ... ... Ghetti B, et al. Genome-wide association meta-analysis of neuropathologic features of Alzheimer's disease and related dementias. Plos Genetics. 10: e1004606. PMID 25188341 DOI: 10.1371/Journal.Pgen.1004606  1
2014 Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, et al. Functional connectivity in autosomal dominant and late-onset Alzheimer disease. Jama Neurology. 71: 1111-22. PMID 25069482 DOI: 10.1001/Jamaneurol.2014.1654  1
2014 Boyd CD, Tierney M, Wassermann EM, Spina S, Oblak AL, Ghetti B, Grafman J, Huey E. Visuoperception test predicts pathologic diagnosis of Alzheimer disease in corticobasal syndrome. Neurology. 83: 510-9. PMID 24991033 DOI: 10.1212/Wnl.0000000000000667  1
2014 Ryman DC, Acosta-Baena N, Aisen PS, Bird T, Danek A, Fox NC, Goate A, Frommelt P, Ghetti B, Langbaum JB, Lopera F, Martins R, Masters CL, Mayeux RP, McDade E, et al. Symptom onset in autosomal dominant Alzheimer disease: a systematic review and meta-analysis. Neurology. 83: 253-60. PMID 24928124 DOI: 10.1212/Wnl.0000000000000596  1
2014 Oblak AL, Hagen MC, Sweadner KJ, Haq I, Whitlow CT, Maldjian JA, Epperson F, Cook JF, Stacy M, Murrell JR, Ozelius LJ, Brashear A, Ghetti B. Rapid-onset dystonia-parkinsonism associated with the I758S mutation of the ATP1A3 gene: a neuropathologic and neuroanatomical study of four siblings. Acta Neuropathologica. 128: 81-98. PMID 24803225 DOI: 10.1007/S00401-014-1279-X  1
2014 Fagan AM, Xiong C, Jasielec MS, Bateman RJ, Goate AM, Benzinger TL, Ghetti B, Martins RN, Masters CL, Mayeux R, Ringman JM, Rossor MN, Salloway S, Schofield PR, Sperling RA, et al. Longitudinal change in CSF biomarkers in autosomal-dominant Alzheimer's disease. Science Translational Medicine. 6: 226ra30. PMID 24598588 DOI: 10.1126/Scitranslmed.3007901  1
2014 Gallagher MD, Suh E, Grossman M, Elman L, McCluskey L, Van Swieten JC, Al-Sarraj S, Neumann M, Gelpi E, Ghetti B, Rohrer JD, Halliday G, Van Broeckhoven C, Seilhean D, Shaw PJ, et al. TMEM106B is a genetic modifier of frontotemporal lobar degeneration with C9orf72 hexanucleotide repeat expansions. Acta Neuropathologica. 127: 407-18. PMID 24442578 DOI: 10.1007/S00401-013-1239-X  1
2014 Hoffmann S, Murrell J, Harms L, Miller K, Meisel A, Brosch T, Scheel M, Ghetti B, Goebel HH, Stenzel W. Enlarging the nosological spectrum of hereditary diffuse leukoencephalopathy with axonal spheroids (HDLS). Brain Pathology (Zurich, Switzerland). 24: 452-8. PMID 24428556 DOI: 10.1111/Bpa.12120  1
2014 Zanusso G, Fiorini M, Ferrari S, Meade-White K, Barbieri I, Brocchi E, Ghetti B, Monaco S. Gerstmann-Sträussler-Scheinker disease and "anchorless prion protein" mice share prion conformational properties diverging from sporadic Creutzfeldt-Jakob disease. The Journal of Biological Chemistry. 289: 4870-81. PMID 24398683 DOI: 10.1074/Jbc.M113.531335  1
2013 Kim S, Nho K, Risacher SL, Inlow M, Swaminathan S, Yoder KK, Shen L, West JD, McDonald BC, Tallman EF, Hutchins GD, Fletcher JW, Farlow MR, Ghetti B, Saykin AJ. PARP1 gene variation and microglial activity on [(11)C]PBR28 PET in older adults at risk for Alzheimer's disease. Multimodal Brain Image Analysis : Third International Workshop, Mbia 2013, Held in Conjunction With Miccai 2013, Nagoya, Japan, September 22, 2013 : Proceedings / Li Shen, Tianming Liu, Pew-Thian Yap, Heng Huang, Dinggang Shen, Carl-Fre.... 8159: 150-158. PMID 25383391 DOI: 10.1007/978-3-319-02126-3_15  1
2013 Alonso Adel C, ElAkkad E, Gong C, Liu F, Tanaka T, Kudo T, Tatebayashi Y, Pei J, Wang J, Khatoon S, Flory M, Ghetti B, Gozes I, Novak M, Novak M, et al. Inge Grundke-Iqbal, Ph.D. (1937–2012): the discoverer of the abnormal hyperphosphorylation of tau in Alzheimer’s disease. Journal of Molecular Neuroscience : Mn. 49: 430-5. PMID 24883456 DOI: 10.1007/S12031-012-9925-Z  1
2013 Benzinger TL, Blazey T, Jack CR, Koeppe RA, Su Y, Xiong C, Raichle ME, Snyder AZ, Ances BM, Bateman RJ, Cairns NJ, Fagan AM, Goate A, Marcus DS, Aisen PS, ... ... Ghetti B, et al. Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 110: E4502-9. PMID 24194552 DOI: 10.1073/Pnas.1317918110  1
2013 Roher AE, Maarouf CL, Malek-Ahmadi M, Wilson J, Kokjohn TA, Daugs ID, Whiteside CM, Kalback WM, Macias MP, Jacobson SA, Sabbagh MN, Ghetti B, Beach TG. Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations. American Journal of Neurodegenerative Disease. 2: 187-207. PMID 24093083  1
2013 Cash DM, Ridgway GR, Liang Y, Ryan NS, Kinnunen KM, Yeatman T, Malone IB, Benzinger TL, Jack CR, Thompson PM, Ghetti BF, Saykin AJ, Masters CL, Ringman JM, Salloway SP, et al. The pattern of atrophy in familial Alzheimer disease: volumetric MRI results from the DIAN study. Neurology. 81: 1425-33. PMID 24049139 DOI: 10.1212/Wnl.0B013E3182A841C6  1
2013 Mills SM, Mallmann J, Santacruz AM, Fuqua A, Carril M, Aisen PS, Althage MC, Belyew S, Benzinger TL, Brooks WS, Buckles VD, Cairns NJ, Clifford D, Danek A, Fagan AM, ... ... Ghetti B, et al. Preclinical trials in autosomal dominant AD: implementation of the DIAN-TU trial. Revue Neurologique. 169: 737-43. PMID 24016464 DOI: 10.1016/J.Neurol.2013.07.017  1
2013 Ahmed Z, Bigio EH, Budka H, Dickson DW, Ferrer I, Ghetti B, Giaccone G, Hatanpaa KJ, Holton JL, Josephs KA, Powers J, Spina S, Takahashi H, White CL, Revesz T, et al. Globular glial tauopathies (GGT): consensus recommendations. Acta Neuropathologica. 126: 537-44. PMID 23995422 DOI: 10.1007/S00401-013-1171-0  1
2013 Kim S, Swaminathan S, Inlow M, Risacher SL, Nho K, Shen L, Foroud TM, Petersen RC, Aisen PS, Soares H, Toledo JB, Shaw LM, Trojanowski JQ, Weiner MW, McDonald BC, ... ... Ghetti B, et al. Influence of genetic variation on plasma protein levels in older adults using a multi-analyte panel. Plos One. 8: e70269. PMID 23894628 DOI: 10.1371/Journal.Pone.0070269  1
2013 Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Ghetti B, et al. Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics. Molecular Psychiatry. 18: 739. PMID 23787478 DOI: 10.1038/Mp.2013.81  1
2013 Sundal C, Fujioka S, Van Gerpen JA, Wider C, Nicholson AM, Baker M, Shuster EA, Aasly J, Spina S, Ghetti B, Roeber S, Garbern J, Tselis A, Swerdlow RH, Miller BB, et al. Parkinsonian features in hereditary diffuse leukoencephalopathy with spheroids (HDLS) and CSF1R mutations. Parkinsonism & Related Disorders. 19: 869-77. PMID 23787135 DOI: 10.1016/J.Parkreldis.2013.05.013  1
2013 Clavaguera F, Akatsu H, Fraser G, Crowther RA, Frank S, Hench J, Probst A, Winkler DT, Reichwald J, Staufenbiel M, Ghetti B, Goedert M, Tolnay M. Brain homogenates from human tauopathies induce tau inclusions in mouse brain. Proceedings of the National Academy of Sciences of the United States of America. 110: 9535-40. PMID 23690619 DOI: 10.1073/Pnas.1301175110  1
2013 Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, ... ... Ghetti B, et al. Whole-exome sequencing and imaging genetics identify functional variants for rate of change in hippocampal volume in mild cognitive impairment. Molecular Psychiatry. 18: 781-7. PMID 23608917 DOI: 10.1038/Mp.2013.24  1
2013 Nalls MA, Duran R, Lopez G, Kurzawa-Akanbi M, McKeith IG, Chinnery PF, Morris CM, Theuns J, Crosiers D, Cras P, Engelborghs S, De Deyn PP, Van Broeckhoven C, Mann DM, Snowden J, ... ... Ghetti B, et al. A multicenter study of glucocerebrosidase mutations in dementia with Lewy bodies. Jama Neurology. 70: 727-35. PMID 23588557 DOI: 10.1001/Jamaneurol.2013.1925  1
2013 Garringer HJ, Murrell J, Sammeta N, Gnezda A, Ghetti B, Vidal R. Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice. Plos One. 8: e56426. PMID 23418567 DOI: 10.1371/Journal.Pone.0056426  1
2013 Spina S, Van Laar AD, Murrell JR, Hamilton RL, Kofler JK, Epperson F, Farlow MR, Lopez OL, Quinlan J, DeKosky ST, Ghetti B. Phenotypic variability in three families with valosin-containing protein mutation. European Journal of Neurology : the Official Journal of the European Federation of Neurological Societies. 20: 251-8. PMID 22900631 DOI: 10.1111/J.1468-1331.2012.03831.X  1
2012 Dickson DW, Miller BL, Ghetti B. American Journal of Neurodegenerative Disease: Editorial Board (2012) e-Century Publishing Corporation. American Journal of Neurodegenerative Disease. 1: 119-21. PMID 23383384  1
2012 Moro ML, Giaccone G, Lombardi R, Indaco A, Uggetti A, Morbin M, Saccucci S, Di Fede G, Catania M, Walsh DM, Demarchi A, Rozemuller A, Bogdanovic N, Bugiani O, Ghetti B, et al. APP mutations in the Aβ coding region are associated with abundant cerebral deposition of Aβ38. Acta Neuropathologica. 124: 809-21. PMID 23143229 DOI: 10.1007/S00401-012-1061-X  1
2012 Morris JC, Aisen PS, Bateman RJ, Benzinger TL, Cairns NJ, Fagan AM, Ghetti B, Goate AM, Holtzman DM, Klunk WE, McDade E, Marcus DS, Martins RN, Masters CL, Mayeux R, et al. Developing an international network for Alzheimer research: The Dominantly Inherited Alzheimer Network. Clinical Investigation. 2: 975-984. PMID 23139856 DOI: 10.4155/Cli.12.93  1
2012 Vidal R, Ghetti B. Generation of a novel murine model of Aβ deposition based on the expression of human wild-type amyloid precursor protein gene. Prion. 6: 346-9. PMID 22874668 DOI: 10.4161/Pri.21023  1
2012 Sundal C, Van Gerpen JA, Nicholson AM, Wider C, Shuster EA, Aasly J, Spina S, Ghetti B, Roeber S, Garbern J, Borjesson-Hanson A, Tselis A, Swerdlow RH, Miller BB, Fujioka S, et al. MRI characteristics and scoring in HDLS due to CSF1R gene mutations. Neurology. 79: 566-74. PMID 22843259 DOI: 10.1212/Wnl.0B013E318263575A  1
2012 Bateman RJ, Xiong C, Benzinger TL, Fagan AM, Goate A, Fox NC, Marcus DS, Cairns NJ, Xie X, Blazey TM, Holtzman DM, Santacruz A, Buckles V, Oliver A, Moulder K, ... ... Ghetti B, et al. Clinical and biomarker changes in dominantly inherited Alzheimer's disease. The New England Journal of Medicine. 367: 795-804. PMID 22784036 DOI: 10.1056/Nejmoa1202753  1
2012 Coppola G, Chinnathambi S, Lee JJ, Dombroski BA, Baker MC, Soto-Ortolaza AI, Lee SE, Klein E, Huang AY, Sears R, Lane JR, Karydas AM, Kenet RO, Biernat J, Wang LS, ... ... Ghetti B, et al. Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases. Human Molecular Genetics. 21: 3500-12. PMID 22556362 DOI: 10.1093/Hmg/Dds161  1
2012 Ferrari R, Mok K, Moreno JH, Cosentino S, Goldman J, Pietrini P, Mayeux R, Tierney MC, Kapogiannis D, Jicha GA, Murrell JR, Ghetti B, Wassermann EM, Grafman J, Hardy J, et al. Screening for C9ORF72 repeat expansion in FTLD. Neurobiology of Aging. 33: 1850.e1-11. PMID 22459598 DOI: 10.1016/J.Neurobiolaging.2012.02.017  1
2012 Vidal R, Sammeta N, Garringer HJ, Sambamurti K, Miravalle L, Lamb BT, Ghetti B. The Psen1-L166P-knock-in mutation leads to amyloid deposition in human wild-type amyloid precursor protein YAC transgenic mice. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 26: 2899-910. PMID 22459153 DOI: 10.1096/Fj.12-205542  1
2012 Monaco S, Fiorini M, Farinazzo A, Ferrari S, Gelati M, Piccardo P, Zanusso G, Ghetti B. Allelic origin of protease-sensitive and protease-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease with the P102L mutation. Plos One. 7: e32382. PMID 22384235 DOI: 10.1371/Journal.Pone.0032382  1
2012 Goedert M, Ghetti B, Spillantini MG. Frontotemporal dementia: implications for understanding Alzheimer disease. Cold Spring Harbor Perspectives in Medicine. 2: a006254. PMID 22355793 DOI: 10.1101/Cshperspect.A006254  1
2012 Rademakers R, Baker M, Nicholson AM, Rutherford NJ, Finch N, Soto-Ortolaza A, Lash J, Wider C, Wojtas A, DeJesus-Hernandez M, Adamson J, Kouri N, Sundal C, Shuster EA, Aasly J, ... ... Ghetti B, et al. Mutations in the colony stimulating factor 1 receptor (CSF1R) gene cause hereditary diffuse leukoencephalopathy with spheroids. Nature Genetics. 44: 200-5. PMID 22197934 DOI: 10.1038/Ng.1027  1
2012 Jeffrey M, McGovern G, Chambers EV, King D, González L, Manson JC, Ghetti B, Piccardo P, Barron RM. Mechanism of PrP-amyloid formation in mice without transmissible spongiform encephalopathy. Brain Pathology (Zurich, Switzerland). 22: 58-66. PMID 21645162 DOI: 10.1111/j.1750-3639.2011.00508.x  1
2011 Vidal R, Ghetti B. Characterization of amyloid deposits in neurodegenerative diseases. Methods in Molecular Biology (Clifton, N.J.). 793: 241-58. PMID 21913105 DOI: 10.1007/978-1-61779-328-8_16  1
2011 Chen-Plotkin AS, Martinez-Lage M, Sleiman PM, Hu W, Greene R, Wood EM, Bing S, Grossman M, Schellenberg GD, Hatanpaa KJ, Weiner MF, White CL, Brooks WS, Halliday GM, Kril JJ, ... ... Ghetti B, et al. Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration. Archives of Neurology. 68: 488-97. PMID 21482928 DOI: 10.1001/Archneurol.2011.53  1
2011 Naj AC, Jun G, Beecham GW, Wang LS, Vardarajan BN, Buros J, Gallins PJ, Buxbaum JD, Jarvik GP, Crane PK, Larson EB, Bird TD, Boeve BF, Graff-Radford NR, De Jager PL, ... ... Ghetti B, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nature Genetics. 43: 436-41. PMID 21460841 DOI: 10.1038/Ng.801  1
2011 Hagen MC, Murrell JR, Delisle MB, Andermann E, Andermann F, Guiot MC, Ghetti B. Encephalopathy with neuroserpin inclusion bodies presenting as progressive myoclonus epilepsy and associated with a novel mutation in the Proteinase Inhibitor 12 gene. Brain Pathology (Zurich, Switzerland). 21: 575-82. PMID 21435071 DOI: 10.1111/J.1750-3639.2011.00481.X  1
2011 Jayadev S, Nochlin D, Poorkaj P, Steinbart EJ, Mastrianni JA, Montine TJ, Ghetti B, Schellenberg GD, Bird TD, Leverenz JB. Familial prion disease with Alzheimer disease-like tau pathology and clinical phenotype. Annals of Neurology. 69: 712-20. PMID 21416485 DOI: 10.1002/Ana.22264  1
2011 Wijsman EM, Pankratz ND, Choi Y, Rothstein JH, Faber KM, Cheng R, Lee JH, Bird TD, Bennett DA, Diaz-Arrastia R, Goate AM, Farlow M, Ghetti B, Sweet RA, Foroud TM, et al. Genome-wide association of familial late-onset Alzheimer's disease replicates BIN1 and CLU and nominates CUGBP2 in interaction with APOE. Plos Genetics. 7: e1001308. PMID 21379329 DOI: 10.1371/Journal.Pgen.1001308  1
2011 Bellucci A, Bugiani O, Ghetti B, Spillantini MG. Presence of reactive microglia and neuroinflammatory mediators in a case of frontotemporal dementia with P301S mutation. Neuro-Degenerative Diseases. 8: 221-9. PMID 21212632 DOI: 10.1159/000322228  1
2011 Espay AJ, Spina S, Houghton DJ, Murrell JR, de Courten-Myers GM, Ghetti B, Litvan I. Rapidly progressive atypical parkinsonism associated with frontotemporal lobar degeneration and motor neuron disease. Journal of Neurology, Neurosurgery, and Psychiatry. 82: 751-3. PMID 20587488 DOI: 10.1136/Jnnp.2009.201608  1
2010 Barbeito AG, Levade T, Delisle MB, Ghetti B, Vidal R. Abnormal iron metabolism in fibroblasts from a patient with the neurodegenerative disease hereditary ferritinopathy. Molecular Neurodegeneration. 5: 50. PMID 21067605 DOI: 10.1186/1750-1326-5-50  1
2010 Parchi P, Cescatti M, Notari S, Schulz-Schaeffer WJ, Capellari S, Giese A, Zou WQ, Kretzschmar H, Ghetti B, Brown P. Agent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease. Brain : a Journal of Neurology. 133: 3030-42. PMID 20823086 DOI: 10.1093/Brain/Awq234  1
2010 Garcia-Reitböck P, Anichtchik O, Bellucci A, Iovino M, Ballini C, Fineberg E, Ghetti B, Della Corte L, Spano P, Tofaris GK, Goedert M, Spillantini MG. SNARE protein redistribution and synaptic failure in a transgenic mouse model of Parkinson's disease. Brain : a Journal of Neurology. 133: 2032-44. PMID 20534649 DOI: 10.1093/Brain/Awq132  1
2010 Van Deerlin VM, Sleiman PM, Martinez-Lage M, Chen-Plotkin A, Wang LS, Graff-Radford NR, Dickson DW, Rademakers R, Boeve BF, Grossman M, Arnold SE, Mann DM, Pickering-Brown SM, Seelaar H, Heutink P, ... ... Ghetti B, et al. Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions. Nature Genetics. 42: 234-9. PMID 20154673 DOI: 10.1038/Ng.536  1
2010 Cupidi C, Capobianco R, Goffredo D, Marcon G, Ghetti B, Bugiani O, Tagliavini F, Giaccone G. Neocortical variation of Abeta load in fully expressed, pure Alzheimer's disease. Journal of Alzheimer's Disease : Jad. 19: 57-68. PMID 20061626 DOI: 10.3233/Jad-2010-1205  1
2010 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update. Acta Neuropathologica. 119: 1-4. PMID 19924424 DOI: 10.1007/S00401-009-0612-2  1
2010 Garringer HJ, Murrell J, D'Adamio L, Ghetti B, Vidal R. Modeling familial British and Danish dementia. Brain Structure & Function. 214: 235-44. PMID 19779737 DOI: 10.1007/S00429-009-0221-9  1
2010 Kepe V, Ghetti B, Farlow MR, Bresjanac M, Miller K, Huang SC, Wong KP, Murrell JR, Piccardo P, Epperson F, Repovs G, Smid LM, Petric A, Siddarth P, Liu J, et al. PET of brain prion protein amyloid in Gerstmann-Sträussler-Scheinker disease. Brain Pathology (Zurich, Switzerland). 20: 419-30. PMID 19725833 DOI: 10.1111/J.1750-3639.2009.00306.X  1
2009 Albrecht S, Bogdanovic N, Ghetti B, Winblad B, LeBlanc AC. Caspase-6 activation in familial alzheimer disease brains carrying amyloid precursor protein or presenilin i or presenilin II mutations. Journal of Neuropathology and Experimental Neurology. 68: 1282-93. PMID 19915487 DOI: 10.1097/NEN.0b013e3181c1da10  1
2009 Huey ED, Pardini M, Cavanagh A, Wassermann EM, Kapogiannis D, Spina S, Ghetti B, Grafman J. Association of ideomotor apraxia with frontal gray matter volume loss in corticobasal syndrome. Archives of Neurology. 66: 1274-80. PMID 19822784 DOI: 10.1001/Archneurol.2009.218  1
2009 Parchi P, Strammiello R, Notari S, Giese A, Langeveld JP, Ladogana A, Zerr I, Roncaroli F, Cras P, Ghetti B, Pocchiari M, Kretzschmar H, Capellari S. Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification. Acta Neuropathologica. 118: 659-71. PMID 19718500 DOI: 10.1007/S00401-009-0585-1  1
2009 Ghetti B. Old age before cognitive impairment. Current Alzheimer Research. 6: 323. PMID 19689229  0.01
2009 Kovacs GG, Murrell JR, Horvath S, Haraszti L, Majtenyi K, Molnar MJ, Budka H, Ghetti B, Spina S. TARDBP variation associated with frontotemporal dementia, supranuclear gaze palsy, and chorea. Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1843-7. PMID 19609911 DOI: 10.1002/Mds.22697  1
2009 Marti J, Santa-Cruz MC, Molina V, Serra R, Bayer SA, Ghetti B, Hervás JP. Regional differences in the vulnerability of substantia nigra dopaminergic neurons in weaver mice. Acta Neurobiologiae Experimentalis. 69: 198-206. PMID 19593334  1
2009 Barbeito AG, Garringer HJ, Baraibar MA, Gao X, Arredondo M, Núñez MT, Smith MA, Ghetti B, Vidal R. Abnormal iron metabolism and oxidative stress in mice expressing a mutant form of the ferritin light polypeptide gene. Journal of Neurochemistry. 109: 1067-78. PMID 19519778 DOI: 10.1111/J.1471-4159.2009.06028.X  1
2009 Ory-Magne F, Brefel-Courbon C, Payoux P, Debruxelles S, Sibon I, Goizet C, Labauge P, Menegon P, Uro-Coste E, Ghetti B, Delisle MB, Vidal R, Rascol O. Clinical phenotype and neuroimaging findings in a French family with hereditary ferritinopathy (FTL498-499InsTC). Movement Disorders : Official Journal of the Movement Disorder Society. 24: 1676-83. PMID 19514068 DOI: 10.1002/Mds.22669  1
2009 Xiao X, Miravalle L, Yuan J, McGeehan J, Dong Z, Wyza R, MacLennan GT, Golichowski AM, Kneale G, King N, Kong Q, Spina S, Vidal R, Ghetti B, Roos K, et al. Failure to detect the presence of prions in the uterine and gestational tissues from a Gravida with Creutzfeldt-Jakob disease. The American Journal of Pathology. 174: 1602-8. PMID 19349373 DOI: 10.2353/Ajpath.2009.081045  1
2009 Giliberto L, Borghi R, Piccini A, Mangerini R, Sorbi S, Cirmena G, Garuti A, Ghetti B, Tagliavini F, Mughal MR, Mattson MP, Zhu X, Wang X, Guglielmotto M, Tamagno E, et al. Mutant presenilin 1 increases the expression and activity of BACE1. The Journal of Biological Chemistry. 284: 9027-38. PMID 19196715 DOI: 10.1074/Jbc.M805685200  1
2009 Mackenzie IR, Neumann M, Bigio EH, Cairns NJ, Alafuzoff I, Kril J, Kovacs GG, Ghetti B, Halliday G, Holm IE, Ince PG, Kamphorst W, Revesz T, Rozemuller AJ, Kumar-Singh S, et al. Nomenclature for neuropathologic subtypes of frontotemporal lobar degeneration: consensus recommendations. Acta Neuropathologica. 117: 15-8. PMID 19015862 DOI: 10.1007/S00401-008-0460-5  1
2009 Vidal R, Barbeito AG, Miravalle L, Ghetti B. Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2. Brain Pathology (Zurich, Switzerland). 19: 58-68. PMID 18410407 DOI: 10.1111/J.1750-3639.2008.00164.X  1
2008 Chiesa R, Piccardo P, Biasini E, Ghetti B, Harris DA. Aggregated, wild-type prion protein causes neurological dysfunction and synaptic abnormalities. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 13258-67. PMID 19052217 DOI: 10.1523/JNEUROSCI.3109-08.2008  1
2008 Maarouf CL, Daugs ID, Spina S, Vidal R, Kokjohn TA, Patton RL, Kalback WM, Luehrs DC, Walker DG, Castaño EM, Beach TG, Ghetti B, Roher AE. Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations. Molecular Neurodegeneration. 3: 20. PMID 19021905 DOI: 10.1186/1750-1326-3-20  1
2008 Kovacs GG, Majtenyi K, Spina S, Murrell JR, Gelpi E, Hoftberger R, Fraser G, Crowther RA, Goedert M, Budka H, Ghetti B. White matter tauopathy with globular glial inclusions: a distinct sporadic frontotemporal lobar degeneration. Journal of Neuropathology and Experimental Neurology. 67: 963-75. PMID 18800011 DOI: 10.1097/Nen.0B013E318187A80F  1
2008 Notari S, Strammiello R, Capellari S, Giese A, Cescatti M, Grassi J, Ghetti B, Langeveld JP, Zou WQ, Gambetti P, Kretzschmar HA, Parchi P. Characterization of truncated forms of abnormal prion protein in Creutzfeldt-Jakob disease. The Journal of Biological Chemistry. 283: 30557-65. PMID 18753138 DOI: 10.1074/Jbc.M801877200  1
2008 Ghetti B, Spina S, Murrell JR, Huey ED, Pietrini P, Sweeney B, Wassermann EM, Keohane C, Farlow MR, Grafman J. In vivo and postmortem clinicoanatomical correlations in frontotemporal dementia and parkinsonism linked to chromosome 17. Neuro-Degenerative Diseases. 5: 215-7. PMID 18322394 DOI: 10.1159/000113706  1
2008 Van Vickle GD, Esh CL, Kokjohn TA, Patton RL, Kalback WM, Luehrs DC, Beach TG, Newel AJ, Lopera F, Ghetti B, Vidal R, Castaño EM, Roher AE. Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's disease. Molecular Medicine (Cambridge, Mass.). 14: 184-94. PMID 18317569 DOI: 10.2119/2007-00094.Vanvickle  1
2008 Velasco A, Fraser G, Delobel P, Ghetti B, Lavenir I, Goedert M. Detection of filamentous tau inclusions by the fluorescent Congo red derivative FSB [(trans,trans)-1-fluoro-2,5-bis(3-hydroxycarbonyl-4-hydroxy)styrylbenzene]. Febs Letters. 582: 901-6. PMID 18291106 DOI: 10.1016/J.Febslet.2008.02.025  1
2008 Vidal R, Miravalle L, Gao X, Barbeito AG, Baraibar MA, Hekmatyar SK, Widel M, Bansal N, Delisle MB, Ghetti B. Expression of a mutant form of the ferritin light chain gene induces neurodegeneration and iron overload in transgenic mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 28: 60-7. PMID 18171923 DOI: 10.1523/Jneurosci.3962-07.2008  1
2008 Delobel P, Lavenir I, Fraser G, Ingram E, Holzer M, Ghetti B, Spillantini MG, Crowther RA, Goedert M. Analysis of tau phosphorylation and truncation in a mouse model of human tauopathy. The American Journal of Pathology. 172: 123-31. PMID 18079436 DOI: 10.2353/Ajpath.2008.070627  1
2008 Spina S, Farlow MR, Unverzagt FW, Kareken DA, Murrell JR, Fraser G, Epperson F, Crowther RA, Spillantini MG, Goedert M, Ghetti B. The tauopathy associated with mutation +3 in intron 10 of Tau: characterization of the MSTD family. Brain : a Journal of Neurology. 131: 72-89. PMID 18065436 DOI: 10.1093/Brain/Awm280  1
2007 Spina S, Murrell JR, Huey ED, Wassermann EM, Pietrini P, Grafman J, Ghetti B. Corticobasal syndrome associated with the A9D Progranulin mutation. Journal of Neuropathology and Experimental Neurology. 66: 892-900. PMID 17917583 DOI: 10.1097/Nen.0B013E3181567873  1
2007 Martí J, Santa-Cruz MC, Bayer SA, Ghetti B, Hervás JP. Purkinje cell age-distribution in fissures and in foliar crowns: a comparative study in the weaver cerebellum. Brain Structure & Function. 212: 347-57. PMID 17899183 DOI: 10.1007/S00429-007-0159-8  1
2007 Filley CM, Rollins YD, Anderson CA, Arciniegas DB, Howard KL, Murrell JR, Boyer PJ, Kleinschmidt-DeMasters BK, Ghetti B. The genetics of very early onset Alzheimer disease. Cognitive and Behavioral Neurology : Official Journal of the Society For Behavioral and Cognitive Neurology. 20: 149-56. PMID 17846513 DOI: 10.1097/Wnn.0B013E318145A8C8  1
2007 Rademakers R, Baker M, Gass J, Adamson J, Huey ED, Momeni P, Spina S, Coppola G, Karydas AM, Stewart H, Johnson N, Hsiung GY, Kelley B, Kuntz K, Steinbart E, ... ... Ghetti B, et al. Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative. The Lancet. Neurology. 6: 857-68. PMID 17826340 DOI: 10.1016/S1474-4422(07)70221-1  1
2007 Ingelsson M, Ramasamy K, Russ C, Freeman SH, Orne J, Raju S, Matsui T, Growdon JH, Frosch MP, Ghetti B, Brown RH, Irizarry MC, Hyman BT. Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains. Acta Neuropathologica. 114: 471-9. PMID 17721707 DOI: 10.1007/S00401-007-0280-Z  1
2007 Martí J, Santa-Cruz MC, Bayer SA, Ghetti B, Hervás JP. Generation and survival of midbrain dopaminergic neurons in weaver mice. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 25: 299-307. PMID 17582722 DOI: 10.1016/J.Ijdevneu.2007.05.002  1
2007 Li A, Piccardo P, Barmada SJ, Ghetti B, Harris DA. Prion protein with an octapeptide insertion has impaired neuroprotective activity in transgenic mice. The Embo Journal. 26: 2777-85. PMID 17510630 DOI: 10.1038/Sj.Emboj.7601726  1
2007 Piccini A, Zanusso G, Borghi R, Noviello C, Monaco S, Russo R, Damonte G, Armirotti A, Gelati M, Giordano R, Zambenedetti P, Russo C, Ghetti B, Tabaton M. Association of a presenilin 1 S170F mutation with a novel Alzheimer disease molecular phenotype. Archives of Neurology. 64: 738-45. PMID 17502474 DOI: 10.1001/Archneur.64.5.738  1
2007 Goedert M, Ghetti B. Alois Alzheimer: his life and times. Brain Pathology (Zurich, Switzerland). 17: 57-62. PMID 17493039 DOI: 10.1111/J.1750-3639.2007.00056.X  1
2007 Piccardo P, Manson JC, King D, Ghetti B, Barron RM. Accumulation of prion protein in the brain that is not associated with transmissible disease. Proceedings of the National Academy of Sciences of the United States of America. 104: 4712-7. PMID 17360589 DOI: 10.1073/pnas.0609241104  1
2007 Baba Y, Baker MC, Le Ber I, Brice A, Maeck L, Kohlhase J, Yasuda M, Stoppe G, Bugiani O, Sperfeld AD, Tsuboi Y, Uitti RJ, Farrer MJ, Ghetti B, Hutton ML, et al. Clinical and genetic features of families with frontotemporal dementia and parkinsonism linked to chromosome 17 with a P301S tau mutation. Journal of Neural Transmission (Vienna, Austria : 1996). 114: 947-50. PMID 17318302 DOI: 10.1007/S00702-007-0632-9  1
2007 Di Fede G, Giaccone G, Limido L, Mangieri M, Suardi S, Puoti G, Morbin M, Mazzoleni G, Ghetti B, Tagliavini F. The epsilon isoform of 14-3-3 protein is a component of the prion protein amyloid deposits of Gerstmann-Sträussler-Scheinker disease. Journal of Neuropathology and Experimental Neurology. 66: 124-30. PMID 17278997 DOI: 10.1097/Nen.0B013E3180302060  1
2007 Spina S, Murrell JR, Huey ED, Wassermann EM, Pietrini P, Baraibar MA, Barbeito AG, Troncoso JC, Vidal R, Ghetti B, Grafman J. Clinicopathologic features of frontotemporal dementia with progranulin sequence variation. Neurology. 68: 820-7. PMID 17202431 DOI: 10.1212/01.Wnl.0000254460.31273.2D  1
2007 Spina S, Murrell JR, Yoshida H, Ghetti B, Bermingham N, Sweeney B, Dlouhy SR, Crowther RA, Goedert M, Keohane C. The novel Tau mutation G335S: clinical, neuropathological and molecular characterization. Acta Neuropathologica. 113: 461-70. PMID 17186252 DOI: 10.1007/S00401-006-0182-5  1
2007 Ringman JM, Rodriguez Y, Diaz-Olavarrieta C, Chavez M, Thompson M, Fairbanks L, Paz F, Varpetian A, Chaparro H, Macias-Islas MA, Murrell J, Ghetti B, Kawas C. Performance on MMSE sub-items and education level in presenilin-1 mutation carriers without dementia. International Psychogeriatrics / Ipa. 19: 323-32. PMID 16805926 DOI: 10.1017/S1041610206003772  1
2006 Ghetti B. Neurodegeneration and hereditary dementias: 40 years of learning. Journal of Alzheimer's Disease : Jad. 9: 45-52. PMID 17004363  0.01
2006 Huey ED, Grafman J, Wassermann EM, Pietrini P, Tierney MC, Ghetti B, Spina S, Baker M, Hutton M, Elder JW, Berger SL, Heflin KA, Hardy J, Momeni P. Characteristics of frontotemporal dementia patients with a Progranulin mutation. Annals of Neurology. 60: 374-80. PMID 16983677 DOI: 10.1002/Ana.20969  1
2006 Ghetti B, Goebel HH. Frontotemporal dementia: the post-tau era. Neurology. 67: 560-1. PMID 16924003 DOI: 10.1212/01.wnl.0000237005.54105.d7  1
2006 Spillantini MG, Murrell JR, Goedert M, Farlow M, Klug A, Ghetti B. Mutations in the tau gene (MAPT) in FTDP-17: the family with Multiple System Tauopathy with Presenile Dementia (MSTD). Journal of Alzheimer's Disease : Jad. 9: 373-80. PMID 16914875 DOI: 10.3233/Jad-2006-9S342  1
2006 Radde R, Bolmont T, Kaeser SA, Coomaraswamy J, Lindau D, Stoltze L, Calhoun ME, Jäggi F, Wolburg H, Gengler S, Haass C, Ghetti B, Czech C, Hölscher C, Mathews PM, et al. Abeta42-driven cerebral amyloidosis in transgenic mice reveals early and robust pathology. Embo Reports. 7: 940-6. PMID 16906128 DOI: 10.1038/Sj.Embor.7400784  1
2006 Wszolek ZK, Tsuboi Y, Ghetti B, Pickering-Brown S, Baba Y, Cheshire WP. Frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Orphanet Journal of Rare Diseases. 1: 30. PMID 16899117 DOI: 10.1186/1750-1172-1-30  1
2006 Murrell J, Ghetti B, Cochran E, Macias-Islas MA, Medina L, Varpetian A, Cummings JL, Mendez MF, Kawas C, Chui H, Ringman JM. The A431E mutation in PSEN1 causing familial Alzheimer's disease originating in Jalisco State, Mexico: an additional fifteen families. Neurogenetics. 7: 277-9. PMID 16897084 DOI: 10.1007/S10048-006-0053-1  1
2006 Schweitzer K, Decker E, Zhu L, Miller RE, Mirra SS, Spina S, Ghetti B, Wang M, Murrell J. Aberrantly regulated proteins in frontotemporal dementia. Biochemical and Biophysical Research Communications. 348: 465-72. PMID 16890190 DOI: 10.1016/J.Bbrc.2006.07.113  1
2006 Moroncini G, Mangieri M, Morbin M, Mazzoleni G, Ghetti B, Gabrielli A, Williamson RA, Giaccone G, Tagliavini F. Pathologic prion protein is specifically recognized in situ by a novel PrP conformational antibody. Neurobiology of Disease. 23: 717-24. PMID 16876426 DOI: 10.1016/j.nbd.2006.06.008  1
2006 Shiarli AM, Jennings R, Shi J, Bailey K, Davidson Y, Tian J, Bigio EH, Ghetti B, Murrell JR, Delisle MB, Mirra S, Crain B, Zolo P, Arima K, Iseki E, et al. Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease. Neuropathology and Applied Neurobiology. 32: 374-87. PMID 16866983 DOI: 10.1111/J.1365-2990.2006.00736.X  1
2006 Colucci M, Moleres FJ, Xie ZL, Ray-Chaudhury A, Gutti S, Butefisch CM, Cervenakova L, Wang W, Goldfarb LG, Kong Q, Ghetti B, Chen SG, Gambetti P. Gerstmann-Sträussler-Scheinker: a new phenotype with 'curly' PrP deposits. Journal of Neuropathology and Experimental Neurology. 65: 642-51. PMID 16825951 DOI: 10.1097/01.Jnen.0000228198.81797.4D  1
2006 Tofaris GK, Garcia Reitböck P, Humby T, Lambourne SL, O'Connell M, Ghetti B, Gossage H, Emson PC, Wilkinson LS, Goedert M, Spillantini MG. Pathological changes in dopaminergic nerve cells of the substantia nigra and olfactory bulb in mice transgenic for truncated human alpha-synuclein(1-120): implications for Lewy body disorders. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 26: 3942-50. PMID 16611810 DOI: 10.1523/Jneurosci.4965-05.2006  1
2006 Baba Y, Ghetti B, Baker MC, Uitti RJ, Hutton ML, Yamaguchi K, Bird T, Lin W, DeLucia MW, Dickson DW, Wszolek ZK. Hereditary diffuse leukoencephalopathy with spheroids: clinical, pathologic and genetic studies of a new kindred. Acta Neuropathologica. 111: 300-11. PMID 16523341 DOI: 10.1007/S00401-006-0046-Z  1
2006 Delobel P, Lavenir I, Ghetti B, Holzer M, Goedert M. Cell-cycle markers in a transgenic mouse model of human tauopathy: increased levels of cyclin-dependent kinase inhibitors p21Cip1 and p27Kip1. The American Journal of Pathology. 168: 878-87. PMID 16507903 DOI: 10.2353/Ajpath.2006.050540  1
2005 Ghetti B. Recognition: Robert Terry. Alzheimer's & Dementia : the Journal of the Alzheimer's Association. 1: 78. PMID 19595824 DOI: 10.1016/j.jalz.2005.06.006  0.01
2005 Castellani RJ, Siedlak SL, Fortino AE, Perry G, Ghetti B, Smith MA. Chitin-like polysaccharides in Alzheimer's disease brains. Current Alzheimer Research. 2: 419-23. PMID 16248847 DOI: 10.2174/156720505774330555  1
2005 Esh C, Patton L, Kalback W, Kokjohn TA, Lopez J, Brune D, Newell AJ, Beach T, Schenk D, Games D, Paul S, Bales K, Ghetti B, Castaño EM, Roher AE. Altered APP processing in PDAPP (Val717 --> Phe) transgenic mice yields extended-length Abeta peptides. Biochemistry. 44: 13807-19. PMID 16229470 DOI: 10.1021/Bi051213+  1
2005 Ringman JM, Diaz-Olavarrieta C, Rodriguez Y, Chavez M, Fairbanks L, Paz F, Varpetian A, Maldonado HC, Macias-Islas MA, Murrell J, Ghetti B, Kawas C. Neuropsychological function in nondemented carriers of presenilin-1 mutations. Neurology. 65: 552-8. PMID 16116115 DOI: 10.1212/01.Wnl.0000172919.50001.D6  1
2005 Petersen RB, Siedlak SL, Lee HG, Kim YS, Nunomura A, Tagliavini F, Ghetti B, Cras P, Moreira PI, Castellani RJ, Guentchev M, Budka H, Ironside JW, Gambetti P, Smith MA, et al. Redox metals and oxidative abnormalities in human prion diseases. Acta Neuropathologica. 110: 232-8. PMID 16096758 DOI: 10.1007/S00401-005-1034-4  1
2005 Miravalle L, Calero M, Takao M, Roher AE, Ghetti B, Vidal R. Amino-terminally truncated Abeta peptide species are the main component of cotton wool plaques. Biochemistry. 44: 10810-21. PMID 16086583 DOI: 10.1021/Bi0508237  1
2005 Yamaguchi K, Cochran EJ, Murrell JR, Polymeropoulos MH, Shannon KM, Crowther RA, Goedert M, Ghetti B. Abundant neuritic inclusions and microvacuolar changes in a case of diffuse Lewy body disease with the A53T mutation in the alpha-synuclein gene. Acta Neuropathologica. 110: 298-305. PMID 15981014 DOI: 10.1007/S00401-005-1042-4  1
2005 Baba Y, Tsuboi Y, Baker MC, Uitti RJ, Hutton ML, Dickson DW, Farrer M, Putzke JD, Woodruff BK, Ghetti B, Murrell JR, Boeve BF, Petersen RC, Verpillat P, Brice A, et al. The effect of tau genotype on clinical features in FTDP-17. Parkinsonism & Related Disorders. 11: 205-8. PMID 15878580 DOI: 10.1016/J.Parkreldis.2005.01.003  1
2005 Zaidi SI, Richardson SL, Capellari S, Song L, Smith MA, Ghetti B, Sy MS, Gambetti P, Petersen RB. Characterization of the F198S prion protein mutation: enhanced glycosylation and defective refolding. Journal of Alzheimer's Disease : Jad. 7: 159-71; discussion 1. PMID 15851854 DOI: 10.3233/Jad-2005-7209  1
2005 Gemignani A, Pietrini P, Murrell JR, Glazier BS, Zolo P, Guazzelli M, Ghetti B. Slow wave and rem sleep mechanisms are differently altered in hereditary pick disease associated with the TAU G389R mutation. Archives Italiennes De Biologie. 143: 65-79. PMID 15844669 DOI: 10.4449/Aib.V143I1.340  1
2005 Stewart RS, Piccardo P, Ghetti B, Harris DA. Neurodegenerative illness in transgenic mice expressing a transmembrane form of the prion protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 25: 3469-77. PMID 15800202 DOI: 10.1523/JNEUROSCI.0105-05.2005  1
2005 Chiesa R, Piccardo P, Dossena S, Nowoslawski L, Roth KA, Ghetti B, Harris DA. Bax deletion prevents neuronal loss but not neurological symptoms in a transgenic model of inherited prion disease. Proceedings of the National Academy of Sciences of the United States of America. 102: 238-43. PMID 15618403 DOI: 10.1073/pnas.0406173102  1
2005 Boeve BF, Tremont-Lukats IW, Waclawik AJ, Murrell JR, Hermann B, Jack CR, Shiung MM, Smith GE, Nair AR, Lindor N, Koppikar V, Ghetti B. Longitudinal characterization of two siblings with frontotemporal dementia and parkinsonism linked to chromosome 17 associated with the S305N tau mutation. Brain : a Journal of Neurology. 128: 752-72. PMID 15615814 DOI: 10.1093/Brain/Awh356  1
2004 Vidal R, Delisle MB, Ghetti B. Neurodegeneration caused by proteins with an aberrant carboxyl-terminus. Journal of Neuropathology and Experimental Neurology. 63: 787-800. PMID 15330334 DOI: 10.1093/Jnen/63.8.787  1
2004 Woodruff BK, Baba Y, Hutton ML, Wszolek ZK, Tsuboi Y, Kobayashi T, Ghetti B, Arima K, Yasuda M, Rascol O. Haplotype-phenotype correlations in kindreds with the N279K mutation in the tau gene. Archives of Neurology. 61: 1327; author reply 1. PMID 15313857 DOI: 10.1001/archneur.61.8.1327-a  1
2004 Barmada S, Piccardo P, Yamaguchi K, Ghetti B, Harris DA. GFP-tagged prion protein is correctly localized and functionally active in the brains of transgenic mice. Neurobiology of Disease. 16: 527-37. PMID 15262264 DOI: 10.1016/J.Nbd.2004.05.005  1
2004 Takao M, Ghetti B, Yoshida H, Piccardo P, Narain Y, Murrell JR, Vidal R, Glazier BS, Jakes R, Tsutsui M, Spillantini MG, Crowther RA, Goedert M, Koto A. Early-onset dementia with Lewy bodies. Brain Pathology (Zurich, Switzerland). 14: 137-47. PMID 15193026 DOI: 10.1111/J.1750-3639.2004.Tb00046.X  1
2004 Vidal R, Ghetti B, Takao M, Brefel-Courbon C, Uro-Coste E, Glazier BS, Siani V, Benson MD, Calvas P, Miravalle L, Rascol O, Delisle MB. Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the ferritin light polypeptide gene. Journal of Neuropathology and Experimental Neurology. 63: 363-80. PMID 15099026 DOI: 10.1093/Jnen/63.4.363  1
2004 Vitali A, Piccini A, Borghi R, Fornaro P, Siedlak SL, Smith MA, Gambetti P, Ghetti B, Tabaton M. Soluble amyloid beta-protein is increased in frontotemporal dementia with tau gene mutations. Journal of Alzheimer's Disease : Jad. 6: 45-51. PMID 15004327 DOI: 10.3233/Jad-2004-6106  1
2004 Notari S, Capellari S, Giese A, Westner I, Baruzzi A, Ghetti B, Gambetti P, Kretzschmar HA, Parchi P. Effects of different experimental conditions on the PrPSc core generated by protease digestion: implications for strain typing and molecular classification of CJD. The Journal of Biological Chemistry. 279: 16797-804. PMID 14754888 DOI: 10.1074/Jbc.M313220200  1
2004 Roher AE, Kokjohn TA, Esh C, Weiss N, Childress J, Kalback W, Luehrs DC, Lopez J, Brune D, Kuo YM, Farlow M, Murrell J, Vidal R, Ghetti B. The human amyloid-beta precursor protein770 mutation V717F generates peptides longer than amyloid-beta-(40-42) and flocculent amyloid aggregates. The Journal of Biological Chemistry. 279: 5829-36. PMID 14645225 DOI: 10.1074/Jbc.M311380200  1
2003 De Michele G, Pocchiari M, Petraroli R, Manfredi M, Caneve G, Coppola G, Casali C, Saccà F, Piccardo P, Salvatore E, Berardelli A, Orio M, Barbieri F, Ghetti B, Filla A. Variable phenotype in a P102L Gerstmann-Sträussler-Scheinker Italian family. The Canadian Journal of Neurological Sciences. Le Journal Canadien Des Sciences Neurologiques. 30: 233-6. PMID 12945948 DOI: 10.1017/S0317167100002651  1
2003 Tofaris GK, Razzaq A, Ghetti B, Lilley KS, Spillantini MG. Ubiquitination of alpha-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function. The Journal of Biological Chemistry. 278: 44405-11. PMID 12923179 DOI: 10.1074/Jbc.M308041200  1
2003 Chiesa R, Piccardo P, Quaglio E, Drisaldi B, Si-Hoe SL, Takao M, Ghetti B, Harris DA. Molecular distinction between pathogenic and infectious properties of the prion protein. Journal of Virology. 77: 7611-22. PMID 12805461 DOI: 10.1128/JVI.77.13.7611-7622.2003  1
2003 Powers JM, Byrne NP, Ito M, Takao M, Yankopoulou D, Spillantini MG, Ghetti B. A novel leukoencephalopathy associated with tau deposits primarily in white matter glia. Acta Neuropathologica. 106: 181-7. PMID 12783250 DOI: 10.1007/S00401-003-0719-9  1
2003 Harris DA, Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B. A murine model of a familial prion disease. Clinics in Laboratory Medicine. 23: 175-86. PMID 12733431 DOI: 10.1016/S0272-2712(02)00069-0  1
2003 Ghetti B, Tagliavini F, Takao M, Bugiani O, Piccardo P. Hereditary prion protein amyloidoses. Clinics in Laboratory Medicine. 23: 65-85, viii. PMID 12733425 DOI: 10.1016/S0272-2712(02)00064-1  1
2003 Vidal R, Delisle MB, Rascol O, Ghetti B. Hereditary ferritinopathy. Journal of the Neurological Sciences. 207: 110-1. PMID 12614943  1
2002 Tsuboi Y, Baker M, Hutton ML, Uitti RJ, Rascol O, Delisle MB, Soulages X, Murrell JR, Ghetti B, Yasuda M, Komure O, Kuno S, Arima K, Sunohara N, Kobayashi T, et al. Clinical and genetic studies of families with the tau N279K mutation (FTDP-17). Neurology. 59: 1791-3. PMID 12473774 DOI: 10.1212/01.Wnl.0000038909.49164.4B  1
2002 Allen B, Ingram E, Takao M, Smith MJ, Jakes R, Virdee K, Yoshida H, Holzer M, Craxton M, Emson PC, Atzori C, Migheli A, Crowther RA, Ghetti B, Spillantini MG, et al. Abundant tau filaments and nonapoptotic neurodegeneration in transgenic mice expressing human P301S tau protein. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 22: 9340-51. PMID 12417659 DOI: 10.1523/Jneurosci.22-21-09340.2002  1
2002 Ogunnyi A, Akang EE, Gureje O, Takao M, Piccardo P, Baiyewu O, Hall KS, Ghetti B, Hendrie HC. Dementia with Lewy bodies in a Nigerian: a case report. International Psychogeriatrics / Ipa. 14: 211-8. PMID 12243211 DOI: 10.1017/S1041610202008402  1
2002 Zhong J, Deng J, Ghetti B, Lee WH. Inhibition of insulin-like growth factor I activity contributes to the premature apoptosis of cerebellar granule neuron in weaver mutant mice: in vitro analysis. Journal of Neuroscience Research. 70: 36-45. PMID 12237862 DOI: 10.1002/jnr.10360  1
2002 Adamec E, Murrell JR, Takao M, Hobbs W, Nixon RA, Ghetti B, Vonsattel JP. P301L tauopathy: confocal immunofluorescence study of perinuclear aggregation of the mutated protein. Journal of the Neurological Sciences. 200: 85-93. PMID 12127682 DOI: 10.1016/S0022-510X(02)00150-8  1
2002 Martí J, Wills KV, Ghetti B, Bayer SA. A combined immunohistochemical and autoradiographic method to detect midbrain dopaminergic neurons and determine their time of origin. Brain Research. Brain Research Protocols. 9: 197-205. PMID 12113779  1
2002 Takao M, Ghetti B, Hayakawa I, Ikeda E, Fukuuchi Y, Miravalle L, Piccardo P, Murrell JR, Glazier BS, Koto A. A novel mutation (G217D) in the Presenilin 1 gene ( PSEN1) in a Japanese family: presenile dementia and parkinsonism are associated with cotton wool plaques in the cortex and striatum. Acta Neuropathologica. 104: 155-70. PMID 12111359 DOI: 10.1007/s00401-002-0536-6  1
2002 Davis RL, Shrimpton AE, Carrell RW, Lomas DA, Gerhard L, Baumann B, Lawrence DA, Yepes M, Kim TS, Ghetti B, Piccardo P, Takao M, Lacbawan F, Muenke M, Sifers RN, et al. Association between conformational mutations in neuroserpin and onset and severity of dementia. Lancet. 359: 2242-7. PMID 12103288 DOI: 10.1016/S0140-6736(02)09293-0  1
2002 Tsuboi Y, Uitti RJ, Delisle MB, Ferreira JJ, Brefel-Courbon C, Rascol O, Ghetti B, Murrell JR, Hutton M, Baker M, Wszolek ZK. Clinical features and disease haplotypes of individuals with the N279K tau gene mutation: a comparison of the pallidopontonigral degeneration kindred and a French family. Archives of Neurology. 59: 943-50. PMID 12056930 DOI: 10.1001/Archneur.59.6.943  1
2002 Moehlmann T, Winkler E, Xia X, Edbauer D, Murrell J, Capell A, Kaether C, Zheng H, Ghetti B, Haass C, Steiner H. Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production. Proceedings of the National Academy of Sciences of the United States of America. 99: 8025-30. PMID 12048239 DOI: 10.1073/Pnas.112686799  1
2002 Marti J, Wills KV, Ghetti B, Bayer SA. Regional differences in the Purkinje cells settled pattern: a comparative autoradiographic study in control and homozygous weaver mice. Experimental Neurology. 175: 168-81. PMID 12009769 DOI: 10.1006/exnr.2002.7873  1
2002 Taratuto AL, Piccardo P, Reich EG, Chen SG, Sevlever G, Schultz M, Luzzi AA, Rugiero M, Abecasis G, Endelman M, Garcia AM, Capellari S, Xie Z, Lugaresi E, Gambetti P, ... ... Ghetti B, et al. Insomnia associated with thalamic involvement in E200K Creutzfeldt-Jakob disease. Neurology. 58: 362-7. PMID 11839833 DOI: 10.1212/Wnl.58.3.362  1
2001 Harris DA, Chiesa R, Migheli A, Piccardo P, Ghetti B. Cellular and transgenic models of familial prion diseases. Methods in Molecular Medicine. 59: 149-61. PMID 21374503 DOI: 10.1385/1-59259-134-5:149  1
2001 Atzori C, Ghetti B, Piva R, Srinivasan AN, Zolo P, Delisle MB, Mirra SS, Migheli A. Activation of the JNK/p38 pathway occurs in diseases characterized by tau protein pathology and is related to tau phosphorylation but not to apoptosis. Journal of Neuropathology and Experimental Neurology. 60: 1190-7. PMID 11764091 DOI: 10.1093/Jnen/60.12.1190  1
2001 Takao M, Ghetti B, Murrell JR, Unverzagt FW, Giaccone G, Tagliavini F, Bugiani O, Piccardo P, Hulette CM, Crain BJ, Farlow MR, Heyman A. Ectopic white matter neurons, a developmental abnormality that may be caused by the PSEN1 S169L mutation in a case of familial AD with myoclonus and seizures. Journal of Neuropathology and Experimental Neurology. 60: 1137-52. PMID 11764087 DOI: 10.1093/Jnen/60.12.1137  1
2001 Panegyres PK, Toufexis K, Kakulas BA, Cernevakova L, Brown P, Ghetti B, Piccardo P, Dlouhy SR. A new PRNP mutation (G131V) associated with Gerstmann-Sträussler-Scheinker disease. Archives of Neurology. 58: 1899-902. PMID 11709001  1
2001 Martí J, Wills KV, Ghetti B, Bayer SA. Evidence that the loss of Purkinje cells and deep cerebellar nuclei neurons in homozygous weaver is not related to neurogenetic patterns. International Journal of Developmental Neuroscience : the Official Journal of the International Society For Developmental Neuroscience. 19: 599-610. PMID 11600321  1
2001 Piccardo P, Liepnieks JJ, William A, Dlouhy SR, Farlow MR, Young K, Nochlin D, Bird TD, Nixon RR, Ball MJ, DeCarli C, Bugiani O, Tagliavini F, Benson MD, Ghetti B. Prion proteins with different conformations accumulate in Gerstmann-Sträussler-Scheinker disease caused by A117V and F198S mutations. The American Journal of Pathology. 158: 2201-7. PMID 11395398 DOI: 10.1016/S0002-9440(10)64692-5  1
2001 Chiesa R, Pestronk A, Schmidt RE, Tourtellotte WG, Ghetti B, Piccardo P, Harris DA. Primary myopathy and accumulation of PrPSc-like molecules in peripheral tissues of transgenic mice expressing a prion protein insertional mutation. Neurobiology of Disease. 8: 279-88. PMID 11300723 DOI: 10.1006/Nbdi.2001.0400  1
2001 Levy E, Sastre M, Kumar A, Gallo G, Piccardo P, Ghetti B, Tagliavini F. Codeposition of cystatin C with amyloid-beta protein in the brain of Alzheimer disease patients. Journal of Neuropathology and Experimental Neurology. 60: 94-104. PMID 11202179  1
2001 Yazaki M, Liepnieks JJ, Murrell JR, Takao M, Guenther B, Piccardo P, Farlow MR, Ghetti B, Benson MD. Biochemical characterization of a neuroserpin variant associated with hereditary dementia. The American Journal of Pathology. 158: 227-33. PMID 11141496 DOI: 10.1016/S0002-9440(10)63961-2  1
2001 Tagliavini F, Lievens PM, Tranchant C, Warter JM, Mohr M, Giaccone G, Perini F, Rossi G, Salmona M, Piccardo P, Ghetti B, Beavis RC, Bugiani O, Frangione B, Prelli F. A 7-kDa prion protein (PrP) fragment, an integral component of the PrP region required for infectivity, is the major amyloid protein in Gerstmann-Sträussler-Scheinker disease A117V. The Journal of Biological Chemistry. 276: 6009-15. PMID 11087738 DOI: 10.1074/Jbc.M007062200  1
2000 Harris DA, Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B. A transgenic model of a familial prion disease. Archives of Virology. Supplementum. 103-12. PMID 11214912 DOI: 10.1007/978-3-7091-6308-5_9  1
2000 Goedert M, Ghetti B, Spillantini MG. Tau gene mutations in frontotemporal dementia and parkinsonism linked to chromosome 17 (FTDP-17). Their relevance for understanding the neurogenerative process. Annals of the New York Academy of Sciences. 920: 74-83. PMID 11193179 DOI: 10.1111/J.1749-6632.2000.Tb06907.X  1
2000 Ghetti B, Murrell JR, Zolo P, Spillantini MG, Goedert M. Progress in hereditary tauopathies: a mutation in the Tau gene (G389R) causes a Pick disease-like syndrome. Annals of the New York Academy of Sciences. 920: 52-62. PMID 11193177 DOI: 10.1111/J.1749-6632.2000.Tb06905.X  1
2000 Takao M, Benson MD, Murrell JR, Yazaki M, Piccardo P, Unverzagt FW, Davis RL, Holohan PD, Lawrence DA, Richardson R, Farlow MR, Ghetti B. Neuroserpin mutation S52R causes neuroserpin accumulation in neurons and is associated with progressive myoclonus epilepsy. Journal of Neuropathology and Experimental Neurology. 59: 1070-86. PMID 11138927 DOI: 10.1093/Jnen/59.12.1070  1
2000 Delisle MB, Uro-Coste E, Murrell JR, Rascol O, Ghetti B. [Neurodegenerative disease associated with a mutation of codon 279 (N279K) in exon 10 of Tau protein]. Bulletin De L'Acadã©Mie Nationale De Mã©Decine. 184: 799-809; discussion . PMID 10989564  1
2000 Lippa CF, Swearer JM, Kane KJ, Nochlin D, Bird TD, Ghetti B, Nee LE, St George-Hyslop P, Pollen DA, Drachman DA. Familial Alzheimer's disease: site of mutation influences clinical phenotype. Annals of Neurology. 48: 376-9. PMID 10976645 DOI: 10.1002/1531-8249(200009)48:3<376::Aid-Ana13>3.0.Co;2-U  1
2000 Parchi P, Zou W, Wang W, Brown P, Capellari S, Ghetti B, Kopp N, Schulz-Schaeffer WJ, Kretzschmar HA, Head MW, Ironside JW, Gambetti P, Chen SG. Genetic influence on the structural variations of the abnormal prion protein. Proceedings of the National Academy of Sciences of the United States of America. 97: 10168-72. PMID 10963679 DOI: 10.1073/Pnas.97.18.10168  1
2000 Martí J, Wills KV, Ghetti B, Bayer SA. The weaver gene continues to target late-generated dopaminergic neurons in midbrain areas at P90. Brain Research. Developmental Brain Research. 122: 173-81. PMID 10960686  1
2000 Martí J, Wills KV, Ghetti B, Bayer SA. The weaver gene has no effect on the generation patterns of mesencephalic dopaminergic neurons. Brain Research. Developmental Brain Research. 122: 165-72. PMID 10960685  1
2000 Vidal R, Calero M, Piccardo P, Farlow MR, Unverzagt FW, Méndez E, Jiménez-Huete A, Beavis R, Gallo G, Gomez-Tortosa E, Ghiso J, Hyman BT, Frangione B, Ghetti B. Senile dementia associated with amyloid beta protein angiopathy and tau perivascular pathology but not neuritic plaques in patients homozygous for the APOE-epsilon4 allele. Acta Neuropathologica. 100: 1-12. PMID 10912914 DOI: 10.1007/S004010051186  1
2000 Bugiani O, Giaccone G, Piccardo P, Morbin M, Tagliavini F, Ghetti B. Neuropathology of Gerstmann-Sträussler-Scheinker disease. Microscopy Research and Technique. 50: 10-5. PMID 10871543 DOI: 10.1002/1097-0029(20000701)50:1<10::Aid-Jemt3>3.0.Co;2-6  1
2000 Murrell JR, Hake AM, Quaid KA, Farlow MR, Ghetti B. Early-onset Alzheimer disease caused by a new mutation (V717L) in the amyloid precursor protein gene. Archives of Neurology. 57: 885-7. PMID 10867787 DOI: 10.1001/Archneur.57.6.885  1
2000 Russo C, Schettini G, Saido TC, Hulette C, Lippa C, Lannfelt L, Ghetti B, Gambetti P, Tabaton M, Teller JK. Presenilin-1 mutations in Alzheimer's disease. Nature. 405: 531-2. PMID 10850703 DOI: 10.1038/35014735  1
2000 Chiesa R, Drisaldi B, Quaglio E, Migheli A, Piccardo P, Ghetti B, Harris DA. Accumulation of protease-resistant prion protein (PrP) and apoptosis of cerebellar granule cells in transgenic mice expressing a PrP insertional mutation. Proceedings of the National Academy of Sciences of the United States of America. 97: 5574-9. PMID 10805813 DOI: 10.1073/pnas.97.10.5574  1
2000 Harkins AB, Dlouhy S, Ghetti B, Cahill AL, Won L, Heller B, Heller A, Fox AP. Evidence of elevated intracellular calcium levels in weaver homozygote mice. The Journal of Physiology. 524: 447-55. PMID 10766925 DOI: 10.1111/J.1469-7793.2000.T01-2-00447.X  1
1999 Ghetti B, Murrell J, Spillantini MG. Mutations in the Tau gene cause frontotemporal dementia. Brain Research Bulletin. 50: 471-2. PMID 10643489 DOI: 10.1016/S0361-9230(99)00139-2  1
1999 Bales KR, Verina T, Cummins DJ, Du Y, Dodel RC, Saura J, Fishman CE, DeLong CA, Piccardo P, Petegnief V, Ghetti B, Paul SM. Apolipoprotein E is essential for amyloid deposition in the APP(V717F) transgenic mouse model of Alzheimer's disease. Proceedings of the National Academy of Sciences of the United States of America. 96: 15233-8. PMID 10611368 DOI: 10.1073/Pnas.96.26.15233  1
1999 Murrell JR, Spillantini MG, Zolo P, Guazzelli M, Smith MJ, Hasegawa M, Redi F, Crowther RA, Pietrini P, Ghetti B, Goedert M. Tau gene mutation G389R causes a tauopathy with abundant pick body-like inclusions and axonal deposits. Journal of Neuropathology and Experimental Neurology. 58: 1207-26. PMID 10604746 DOI: 10.1097/00005072-199912000-00002  1
1999 Zhang W, Ghetti B, Yang XL, Lee W. Alteration of IGF system gene expression during the postnatal development of pcd mice. The Journal of Endocrinology. 163: 191-8. PMID 10556767 DOI: 10.1677/joe.0.1630191  1
1999 Broome JD, Wills KV, Lapchak PA, Ghetti B, Camp LL, Bayer SA. Glial cell line-derived neurotrophic factor protects midbrain dopamine neurons from the lethal action of the weaver gene: a quantitative immunocytochemical study. Brain Research. Developmental Brain Research. 116: 1-7. PMID 10446341 DOI: 10.1016/S0165-3806(99)00065-6  1
1999 Parchi P, Giese A, Capellari S, Brown P, Schulz-Schaeffer W, Windl O, Zerr I, Budka H, Kopp N, Piccardo P, Poser S, Rojiani A, Streichemberger N, Julien J, Vital C, ... Ghetti B, et al. Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects. Annals of Neurology. 46: 224-33. PMID 10443888 DOI: 10.1002/1531-8249(199908)46:2<224::Aid-Ana12>3.0.Co;2-W  1
1999 Migheli A, Piva R, Casolino S, Atzori C, Dlouhy SR, Ghetti B. A cell cycle alteration precedes apoptosis of granule cell precursors in the weaver mouse cerebellum. The American Journal of Pathology. 155: 365-73. PMID 10433930 DOI: 10.1016/S0002-9440(10)65133-4  1
1999 Delisle MB, Murrell JR, Richardson R, Trofatter JA, Rascol O, Soulages X, Mohr M, Calvas P, Ghetti B. A mutation at codon 279 (N279K) in exon 10 of the Tau gene causes a tauopathy with dementia and supranuclear palsy. Acta Neuropathologica. 98: 62-77. PMID 10412802  1
1999 Varani L, Hasegawa M, Spillantini MG, Smith MJ, Murrell JR, Ghetti B, Klug A, Goedert M, Varani G. Structure of tau exon 10 splicing regulatory element RNA and destabilization by mutations of frontotemporal dementia and parkinsonism linked to chromosome 17. Proceedings of the National Academy of Sciences of the United States of America. 96: 8229-34. PMID 10393977 DOI: 10.1073/Pnas.96.14.8229  1
1999 Bugiani O, Murrell JR, Giaccone G, Hasegawa M, Ghigo G, Tabaton M, Morbin M, Primavera A, Carella F, Solaro C, Grisoli M, Savoiardo M, Spillantini MG, Tagliavini F, Goedert M, ... Ghetti B, et al. Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 667-77. PMID 10374757 DOI: 10.1097/00005072-199906000-00011  1
1999 Mirra SS, Murrell JR, Gearing M, Spillantini MG, Goedert M, Crowther RA, Levey AI, Jones R, Green J, Shoffner JM, Wainer BH, Schmidt ML, Trojanowski JQ, Ghetti B. Tau pathology in a family with dementia and a P301L mutation in tau. Journal of Neuropathology and Experimental Neurology. 58: 335-45. PMID 10218629 DOI: 10.1097/00005072-199904000-00004  1
1998 Chiesa R, Piccardo P, Ghetti B, Harris DA. Neurological illness in transgenic mice expressing a prion protein with an insertional mutation. Neuron. 21: 1339-51. PMID 9883727 DOI: 10.1016/S0896-6273(00)80653-4  1
1998 Schwartz NB, Szabo M, Verina T, Wei J, Dlouhy SR, Won L, Heller A, Hodes ME, Ghetti B. Hypothalamic-pituitary-gonadal axis in the mutant weaver mouse. Neuroendocrinology. 68: 374-85. PMID 9873201 DOI: 10.1159/000054387  1
1998 Fox AP, Dlouhy S, Ghetti B, Hurley JH, Nucifora PG, Nelson DJ, Won L, Heller A. Altered responses to potassium in cerebellar neurons from weaver heterozygote mice. Experimental Brain Research. 123: 298-306. PMID 9860268 DOI: 10.1007/S002210050572  1
1998 Jiménez-Huete A, Lievens PM, Vidal R, Piccardo P, Ghetti B, Tagliavini F, Frangione B, Prelli F. Endogenous proteolytic cleavage of normal and disease-associated isoforms of the human prion protein in neural and non-neural tissues. The American Journal of Pathology. 153: 1561-72. PMID 9811348 DOI: 10.1016/S0002-9440(10)65744-6  1
1998 Lippa CF, Fujiwara H, Mann DM, Giasson B, Baba M, Schmidt ML, Nee LE, O'Connell B, Pollen DA, St George-Hyslop P, Ghetti B, Nochlin D, Bird TD, Cairns NJ, Lee VM, et al. Lewy bodies contain altered alpha-synuclein in brains of many familial Alzheimer's disease patients with mutations in presenilin and amyloid precursor protein genes. The American Journal of Pathology. 153: 1365-70. PMID 9811326 DOI: 10.1016/S0002-9440(10)65722-7  1
1998 Piccardo P, Dlouhy SR, Lievens PM, Young K, Bird TD, Nochlin D, Dickson DW, Vinters HV, Zimmerman TR, Mackenzie IR, Kish SJ, Ang LC, De Carli C, Pocchiari M, Brown P, ... ... Ghetti B, et al. Phenotypic variability of Gerstmann-Sträussler-Scheinker disease is associated with prion protein heterogeneity. Journal of Neuropathology and Experimental Neurology. 57: 979-88. PMID 9786248 DOI: 10.1097/00005072-199810000-00010  1
1998 Wei J, Hodes ME, Piva R, Feng Y, Wang Y, Ghetti B, Dlouhy SR. Characterization of murine Girk2 transcript isoforms: structure and differential expression. Genomics. 51: 379-90. PMID 9721208 DOI: 10.1006/Geno.1998.5369  1
1998 Spillantini MG, Murrell JR, Goedert M, Farlow MR, Klug A, Ghetti B. Mutation in the tau gene in familial multiple system tauopathy with presenile dementia. Proceedings of the National Academy of Sciences of the United States of America. 95: 7737-41. PMID 9636220 DOI: 10.1073/Pnas.95.13.7737  1
1998 Piccardo P, Langeveld JP, Hill AF, Dlouhy SR, Young K, Giaccone G, Rossi G, Bugiani M, Bugiani O, Meloen RH, Collinge J, Tagliavini F, Ghetti B. An antibody raised against a conserved sequence of the prion protein recognizes pathological isoforms in human and animal prion diseases, including Creutzfeldt-Jakob disease and bovine spongiform encephalopathy. The American Journal of Pathology. 152: 1415-20. PMID 9626045  1
1998 Spillantini MG, Bird TD, Ghetti B. Frontotemporal dementia and Parkinsonism linked to chromosome 17: a new group of tauopathies. Brain Pathology (Zurich, Switzerland). 8: 387-402. PMID 9546295 DOI: 10.1111/J.1750-3639.1998.Tb00162.X  1
1998 Salanova V, Markand O, Worth R, Smith R, Wellman H, Hutchins G, Park H, Ghetti B, Azzarelli B. FDG-PET and MRI in temporal lobe epilepsy: relationship to febrile seizures, hippocampal sclerosis and outcome. Acta Neurologica Scandinavica. 97: 146-53. PMID 9531429 DOI: 10.1111/J.1600-0404.1998.TB00628.X  1
1998 Brown P, Cervenáková L, McShane L, Goldfarb LG, Bishop K, Bastian F, Kirkpatrick J, Piccardo P, Ghetti B, Gajdusek DC. Creutzfeldt-Jakob disease in a husband and wife. Neurology. 50: 684-8. PMID 9521256 DOI: 10.1212/WNL.50.3.684  1
1997 Migheli A, Piva R, Wei J, Attanasio A, Casolino S, Hodes ME, Dlouhy SR, Bayer SA, Ghetti B. Diverse cell death pathways result from a single missense mutation in weaver mouse. The American Journal of Pathology. 151: 1629-38. PMID 9403713  1
1997 Bales KR, Verina T, Dodel RC, Du Y, Altstiel L, Bender M, Hyslop P, Johnstone EM, Little SP, Cummins DJ, Piccardo P, Ghetti B, Paul SM. Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition. Nature Genetics. 17: 263-4. PMID 9354781 DOI: 10.1038/Ng1197-263  1
1997 Murrell JR, Koller D, Foroud T, Goedert M, Spillantini MG, Edenberg HJ, Farlow MR, Ghetti B. Familial multiple-system tauopathy with presenile dementia is localized to chromosome 17. American Journal of Human Genetics. 61: 1131-8. PMID 9345089 DOI: 10.1086/301594  1
1997 Won L, Ghetti B, Heller B, Heller A. In vitro evidence that the reduction in mesencephalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction. Experimental Brain Research. 115: 174-9. PMID 9224846 DOI: 10.1007/Pl00005679  1
1997 Wei J, Dlouhy SR, Bayer S, Piva R, Verina T, Wang Y, Feng Y, Dupree B, Hodes ME, Ghetti B. In situ hybridization analysis of Girk2 expression in the developing central nervous system in normal and weaver mice. Journal of Neuropathology and Experimental Neurology. 56: 762-71. PMID 9210872  1
1997 Simon JR, Bare DJ, Ghetti B, Richter JA. A possible role for tyrosine kinases in the regulation of the neuronal dopamine transporter in mouse striatum. Neuroscience Letters. 224: 201-5. PMID 9131671 DOI: 10.1016/S0304-3940(97)13479-6  1
1997 Unverzagt FW, Farlow MR, Norton J, Dlouhy SR, Young K, Ghetti B. Neuropsychological function in patients with Gerstmann-Sträussler-Scheinker disease from the Indiana kindred (F198S). Journal of the International Neuropsychological Society : Jins. 3: 169-78. PMID 9126858 DOI: 10.1017/S1355617797001690  1
1997 Park DW, Boldt HC, Massicotte SJ, Akang EE, Roos KL, Bodnar A, Pless J, Ghetti B, Pascuzzi RM. Subacute sclerosing panencephalitis manifesting as viral retinitis: clinical and histopathologic findings. American Journal of Ophthalmology. 123: 533-42. PMID 9124250 DOI: 10.1016/S0002-9394(14)70179-5  1
1997 Spillantini MG, Goedert M, Crowther RA, Murrell JR, Farlow MR, Ghetti B. Familial multiple system tauopathy with presenile dementia: a disease with abundant neuronal and glial tau filaments. Proceedings of the National Academy of Sciences of the United States of America. 94: 4113-8. PMID 9108114 DOI: 10.1073/Pnas.94.8.4113  1
1997 Zhang W, Ghetti B, Lee WH. Decreased IGF-I gene expression during the apoptosis of Purkinje cells in pcd mice. Brain Research. Developmental Brain Research. 98: 164-76. PMID 9051257 DOI: 10.1016/S0165-3806(96)00168-X  1
1997 Young K, Clark HB, Piccardo P, Dlouhy SR, Ghetti B. Gerstmann-Sträussler-Scheinker disease with the PRNP P102L mutation and valine at codon 129. Brain Research. Molecular Brain Research. 44: 147-50. PMID 9030710 DOI: 10.1016/S0169-328X(96)00251-3  1
1997 Verina T, Norton JA, Sorbel JJ, Triarhou LC, Laferty D, Richter JA, Simon JR, Ghetti B. Atrophy and loss of dopaminergic mesencephalic neurons in heterozygous weaver mice. Experimental Brain Research. 113: 5-12. PMID 9028770 DOI: 10.1007/Bf02454137  1
1996 Piccardo P, Seiler C, Dlouhy SR, Young K, Farlow MR, Prelli F, Frangione B, Bugiani O, Tagliavini F, Ghetti B. Proteinase-K-resistant prion protein isoforms in Gerstmann-Sträussler-Scheinker disease (Indiana kindred). Journal of Neuropathology and Experimental Neurology. 55: 1157-63. PMID 8939199 DOI: 10.1097/00005072-199611000-00007  1
1996 Bayer SA, Wills KV, Wei J, Feng Y, Dlouhy SR, Hodes ME, Verina T, Ghetti B. Phenotypic effects of the weaver gene are evident in the embryonic cerebellum but not in the ventral midbrain. Brain Research. Developmental Brain Research. 96: 130-7. PMID 8922675 DOI: 10.1016/0165-3806(96)00107-1  1
1996 Wei J, Dlouhy SR, Wang Y, Zhu J, Fitzpatrick L, Ghetti B, Hodes ME. Linkage mapping of microdissected clones from distal mouse chromosome 16. Somatic Cell and Molecular Genetics. 22: 227-32. PMID 8914607 DOI: 10.1007/Bf02369912  1
1996 Wei J, Hodes ME, Wang Y, Feng Y, Ghetti B, Dlouhy SR. Direct cDNA selection with DNA microdissected from mouse chromosome 16: isolation of novel clones and construction of a partial transcription map of the C3-C4 region. Genome Research. 6: 678-87. PMID 8858343 DOI: 10.1101/Gr.6.8.678  1
1996 Ghetti B, Piccardo P, Frangione B, Bugiani O, Giaccone G, Young K, Prelli F, Farlow MR, Dlouhy SR, Tagliavini F. Prion protein amyloidosis. Brain Pathology (Zurich, Switzerland). 6: 127-45. PMID 8737929 DOI: 10.1111/J.1750-3639.1996.Tb00796.X  1
1996 Tong Y, Wei J, Zhang S, Strong JA, Dlouhy SR, Hodes ME, Ghetti B, Yu L. The weaver mutation changes the ion selectivity of the affected inwardly rectifying potassium channel GIRK2. Febs Letters. 390: 63-8. PMID 8706831 DOI: 10.1016/0014-5793(96)00632-1  1
1996 Perini F, Vidal R, Ghetti B, Tagliavini F, Frangione B, Prelli F. PrP27-30 is a normal soluble prion protein fragment released by human platelets. Biochemical and Biophysical Research Communications. 223: 572-7. PMID 8687437 DOI: 10.1006/Bbrc.1996.0936  1
1996 Wei J, Dlouhy SR, Hara A, Ghetti B, Hodes ME. Cloning a cDNA for carbonyl reductase (Cbr) from mouse cerebellum: murine genes that express cbr map to chromosomes 16 and 11. Genomics. 34: 147-8. PMID 8661038 DOI: 10.1006/Geno.1996.0255  1
1996 Parchi P, Castellani R, Capellari S, Ghetti B, Young K, Chen SG, Farlow M, Dickson DW, Sima AA, Trojanowski JQ, Petersen RB, Gambetti P. Molecular basis of phenotypic variability in sporadic Creutzfeldt-Jakob disease. Annals of Neurology. 39: 767-78. PMID 8651649 DOI: 10.1002/Ana.410390613  1
1996 Lippa CF, Saunders AM, Smith TW, Swearer JM, Drachman DA, Ghetti B, Nee L, Pulaski-Salo D, Dickson D, Robitaille Y, Bergeron C, Crain B, Benson MD, Farlow M, Hyman BT, et al. Familial and sporadic Alzheimer's disease: neuropathology cannot exclude a final common pathway. Neurology. 46: 406-12. PMID 8614503 DOI: 10.1212/Wnl.46.2.406  1
1996 Ghetti B, Piccardo P, Spillantini MG, Ichimiya Y, Porro M, Perini F, Kitamoto T, Tateishi J, Seiler C, Frangione B, Bugiani O, Giaccone G, Prelli F, Goedert M, Dlouhy SR, et al. Vascular variant of prion protein cerebral amyloidosis with tau-positive neurofibrillary tangles: the phenotype of the stop codon 145 mutation in PRNP. Proceedings of the National Academy of Sciences of the United States of America. 93: 744-8. PMID 8570627 DOI: 10.1073/Pnas.93.2.744  1
1995 Migheli A, Attanasio A, Lee WH, Bayer SA, Ghetti B. Detection of apoptosis in weaver cerebellum by electron microscopic in situ end-labeling of fragmented DNA. Neuroscience Letters. 199: 53-6. PMID 8584226  1
1995 Richter JA, Bare DJ, Yu H, Ghetti B, Simon JR. Dopamine transporter-dependent and -independent endogenous dopamine release from weaver mouse striatum in vitro. Journal of Neurochemistry. 64: 191-8. PMID 7798913 DOI: 10.1046/J.1471-4159.1995.64010191.X  1
1995 Ghetti B, Dlouhy SR, Giaccone G, Bugiani O, Frangione B, Farlow MR, Tagliavini F. Gerstmann-Sträussler-Scheinker disease and the Indiana kindred. Brain Pathology (Zurich, Switzerland). 5: 61-75. PMID 7767492 DOI: 10.1111/J.1750-3639.1995.Tb00578.X  1
1995 Verina T, Tang X, Fitzpatrick L, Norton J, Vogelweid C, Ghetti B. Degeneration of Sertoli and spermatogenic cells in homozygous and heterozygous weaver mice. Journal of Neurogenetics. 9: 251-65. PMID 7760215  1
1995 Suzuki K, Parker CC, Pentchev PG, Katz D, Ghetti B, D'Agostino AN, Carstea ED. Neurofibrillary tangles in Niemann-Pick disease type C. Acta Neuropathologica. 89: 227-38. PMID 7754743 DOI: 10.1007/BF00309338  1
1995 Triarhou LC, Solà C, Mengod G, García-Ladona FJ, Landwehrmeyer B, Ghetti B, Palacios JM. Ventral mesencephalic grafts in the neostriatum of the weaver mutant mouse: structural molecule and receptor studies. Cell Transplantation. 4: 39-48. PMID 7728332 DOI: 10.1016/0963-6897(94)00037-K  1
1995 Richter JA, Brenneman MG, Dlouhy SR, Ghetti B. Dopaminergic parameters in the striatum and substantia nigra of seven strains of mice: higher density in striatum of CAST compared to BALB mice. Neurochemical Research. 20: 395-400. PMID 7651576 DOI: 10.1007/Bf00973093  1
1995 Lee WH, Wang GM, Lo T, Triarhou LC, Ghetti B. Altered IGFBP5 gene expression in the cerebellar external germinal layer of weaver mutant mice. Brain Research. Molecular Brain Research. 30: 259-68. PMID 7637577  1
1995 Piccardo P, Ghetti B, Dickson DW, Vinters HV, Giaccone G, Bugiani O, Tagliavini F, Young K, Dlouhy SR, Seiler C. Gerstmann-Sträussler-Scheinker disease (PRNP P102L): amyloid deposits are best recognized by antibodies directed to epitopes in PrP region 90-165. Journal of Neuropathology and Experimental Neurology. 54: 790-801. PMID 7595652 DOI: 10.1097/00005072-199511000-00006  1
1995 Bare DJ, Ghetti B, Richter JA. The tyrosine kinase inhibitor genistein increases endogenous dopamine release from normal and weaver mutant mouse striatal slices. Journal of Neurochemistry. 65: 2096-104. PMID 7595495  1
1995 Bayer SA, Wills KV, Triarhou LC, Verina T, Thomas JD, Ghetti B. Selective vulnerability of late-generated dopaminergic neurons of the substantia nigra in weaver mutant mice. Proceedings of the National Academy of Sciences of the United States of America. 92: 9137-40. PMID 7568088  1
1995 Bayer SA, Wills KV, Triarhou LC, Thomas JD, Ghetti B. Systematic differences in time of dopaminergic neuron origin between normal mice and homozygous weaver mutants. Experimental Brain Research. 105: 200-8. PMID 7498373  1
1995 Bayer SA, Wills KV, Triarhou LC, Ghetti B. Time of neuron origin and gradients of neurogenesis in midbrain dopaminergic neurons in the mouse. Experimental Brain Research. 105: 191-9. PMID 7498372  1
1995 Stotz-Potter EH, Ghetti B, Simon JR. Endogenous serotonin release from the dopamine-deficient striatum of the weaver mutant mouse. Neurochemical Research. 20: 821-6. PMID 7477675 DOI: 10.1007/Bf00969694  1
1994 Farlow M, Murrell J, Ghetti B, Unverzagt F, Zeldenrust S, Benson M. Clinical characteristics in a kindred with early-onset Alzheimer's disease and their linkage to a G-->T change at position 2149 of the amyloid precursor protein gene. Neurology. 44: 105-11. PMID 8290042 DOI: 10.1212/Wnl.44.1.105  1
1994 Farlow M, Ghetti B, Dlouhy S, Giaccone G, Bugiani O, Tagliavini F, Wagner S. Cerebrospinal fluid levels of amyloid beta-protein precursor are low in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Neurology. 44: 1508-10. PMID 8058158 DOI: 10.1212/Wnl.44.8.1508  1
1994 Bayer SA, Triarhou LC, Thomas JD, Ghetti B. Correlated quantitative studies of the neostriatum, nucleus accumbens, substantia nigra, and ventral tegmental area in normal and weaver mutant mice. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 14: 6901-10. PMID 7965086  1
1994 Tagliavini F, Prelli F, Porro M, Rossi G, Giaccone G, Farlow MR, Dlouhy SR, Ghetti B, Bugiani O, Frangione B. Amyloid fibrils in Gerstmann-Sträussler-Scheinker disease (Indiana and Swedish kindreds) express only PrP peptides encoded by the mutant allele. Cell. 79: 695-703. PMID 7954833 DOI: 10.1016/0092-8674(94)90554-1  1
1994 Ghetti B, Tagliavini F, Giaccone G, Bugiani O, Frangione B, Farlow MR, Dlouhy SR. Familial Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Molecular Neurobiology. 8: 41-8. PMID 7916191 DOI: 10.1007/Bf02778006  1
1994 Monari L, Chen SG, Brown P, Parchi P, Petersen RB, Mikol J, Gray F, Cortelli P, Montagna P, Ghetti B. Fatal familial insomnia and familial Creutzfeldt-Jakob disease: different prion proteins determined by a DNA polymorphism. Proceedings of the National Academy of Sciences of the United States of America. 91: 2839-42. PMID 7908444 DOI: 10.1073/Pnas.91.7.2839  1
1994 Simon JR, Richter JA, Ghetti B. Age-dependent alterations in dopamine content, tyrosine hydroxylase activity, and dopamine uptake in the striatum of the weaver mutant mouse. Journal of Neurochemistry. 62: 543-8. PMID 7905025 DOI: 10.1046/J.1471-4159.1994.62020543.X  1
1994 Hodes ME, Dlouhy SR, Wei JJ, Wang Y, Sangameswaran L, Lazar V, Triarhou LC, Ghetti B. cDNA approaches to isolation of the mouse mutant weaver gene. Neurochemical Research. 19: 1359-62. PMID 7898606 DOI: 10.1007/Bf00972463  1
1994 Triarhou LC, Stotz EH, Low WC, Norton J, Ghetti B, Landwehrmeyer B, Palacios JM, Simon JR. Studies on the striatal dopamine uptake system of weaver mutant mice and effects of ventral mesencephalic grafts. Neurochemical Research. 19: 1349-58. PMID 7898605 DOI: 10.1007/Bf00972462  1
1994 Stotz EH, Palacios JM, Landwehrmeyer B, Norton J, Ghetti B, Simon JR, Triarhou LC. Alterations in dopamine and serotonin uptake systems in the striatum of the weaver mutant mouse. Journal of Neural Transmission. General Section. 97: 51-64. PMID 7888149 DOI: 10.1007/Bf01277962  1
1994 Simon JR, Ghetti B. The weaver mutant mouse as a model of nigrostriatal dysfunction. Molecular Neurobiology. 9: 183-9. PMID 7888095 DOI: 10.1007/BF02816118  1
1994 Wei J, Dlouhy SR, Zhu J, Ghetti B, Hodes ME. Analysis of region-specific library constructed by sequence-independent amplification of microdissected fragments surrounding weaver (wv) gene on mouse chromosome 16. Somatic Cell and Molecular Genetics. 20: 401-8. PMID 7825062 DOI: 10.1007/Bf02257457  1
1994 Kambouris M, Sangameswaran L, Triarhou LC, Kozak CA, Dlouhy SR, Ghetti B, Hodes ME. Molecular characterization of a novel cDNA from murine cerebellum, developmental expression, and distribution in brain. Brain Research. Molecular Brain Research. 25: 192-9. PMID 7808217 DOI: 10.1016/0169-328X(94)90153-8  1
1994 Kambouris M, Triarhou LC, Dlouhy SR, Sangameswaran L, Luo F, Ghetti B, Hodes ME. Novel cDNA clones obtained by antibody screening of a mouse cerebellar cDNA expression library. Brain Research. Molecular Brain Research. 25: 183-91. PMID 7808216 DOI: 10.1016/0169-328X(94)90152-X  1
1993 Solà C, Mengod G, Ghetti B, Palacios JM, Triarhou LC. Regional distribution of the alternatively spliced isoforms of beta APP RNA transcript in the brain of normal, heterozygous and homozygous weaver mutant mice as revealed by in situ hybridization histochemistry. Brain Research. Molecular Brain Research. 17: 340-6. PMID 8510506 DOI: 10.1016/0169-328X(93)90020-P  1
1993 Stotz EH, Triarhou LC, Ghetti B, Simon JR. Serotonin content is elevated in the dopamine deficient striatum of the weaver mutant mouse. Brain Research. 606: 267-72. PMID 8490719 DOI: 10.1016/0006-8993(93)90994-X  1
1993 Simon JR, Ghetti B. Is there a significant somatodendritic uptake of dopamine in the substantia nigra? Evidence from the weaver mutant mouse. Neurochemistry International. 22: 471-7. PMID 8485453 DOI: 10.1016/0197-0186(93)90042-4  1
1993 Tagliavini F, Giaccone G, Prelli F, Verga L, Porro M, Trojanowski JQ, Farlow MR, Frangione B, Ghetti B, Bugiani O. A68 is a component of paired helical filaments of Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Brain Research. 616: 325-9. PMID 8358624 DOI: 10.1016/0006-8993(93)90226-D  1
1993 Kambouris M, Sangameswaran L, Dlouhy SR, Hodes ME, Ghetti B, Triarhou LC. Cellular distribution of the RNA transcripts of a newly discovered gene in the brain of normal, weaver, Purkinje cell degeneration and reeler mutant mice as evidenced by in situ hybridization histochemistry. Brain Research. Molecular Brain Research. 18: 321-8. PMID 8326827 DOI: 10.1016/0169-328X(93)90096-8  1
1993 Solà C, Mengod G, Low WC, Norton J, Ghetti B, Palacios JM, Triarhou LC. Regional distribution of amyloid beta-protein precursor, growth-associated phosphoprotein-43 and microtubule-associated protein 2 messenger RNAs in the nigrostriatal system of normal and Weaver mutant mice and effects of ventral mesencephalic grafts. The European Journal of Neuroscience. 5: 1442-54. PMID 8287193 DOI: 10.1111/J.1460-9568.1993.Tb00212.X  1
1993 Liepnieks JJ, Ghetti B, Farlow M, Roses AD, Benson MD. Characterization of amyloid fibril beta-peptide in familial Alzheimer's disease with APP717 mutations. Biochemical and Biophysical Research Communications. 197: 386-92. PMID 8267572 DOI: 10.1006/Bbrc.1993.2491  1
1993 Chang AC, Ghetti B. Embryonic cerebellar graft development during acute phase of gliosis in the cerebellum of pcd mutant mice. The Chinese Journal of Physiology. 36: 141-9. PMID 8194390  1
1993 Richter JA, Ghetti B, Simon JR. Dopamine-depleting effects of MPTP and reserpine in weaver mutant mice. Molecular and Chemical Neuropathology / Sponsored by the International Society For Neurochemistry and the World Federation of Neurology and Research Groups On Neurochemistry and Cerebrospinal Fluid. 20: 219-28. PMID 8172626 DOI: 10.1007/Bf03160075  1
1993 Vogelweid CM, Verina T, Norton J, Harruff R, Ghetti B. Hypospermatogenesis is the cause of infertility in the male weaver mutant mouse. Journal of Neurogenetics. 9: 89-104. PMID 8126599  1
1993 Tagliavini F, Prelli F, Verga L, Giaccone G, Sarma R, Gorevic P, Ghetti B, Passerini F, Ghibaudi E, Forloni G. Synthetic peptides homologous to prion protein residues 106-147 form amyloid-like fibrils in vitro. Proceedings of the National Academy of Sciences of the United States of America. 90: 9678-82. PMID 8105481 DOI: 10.1073/Pnas.90.20.9678  1
1993 Bugiani O, Giaccone G, Verga L, Pollo B, Frangione B, Farlow MR, Tagliavini F, Ghetti B. Beta PP participates in PrP-amyloid plaques of Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Journal of Neuropathology and Experimental Neurology. 52: 64-70. PMID 8093899 DOI: 10.1097/00005072-199301000-00008  1
1993 Zeldenrust SR, Murrell J, Farlow M, Ghetti B, Roses AD, Benson MD. RFLP analysis for APP 717 mutations associated with Alzheimer's disease. Journal of Medical Genetics. 30: 476-8. PMID 7686976  1
1992 Yee RD, Farlow MR, Suzuki DA, Betelak KF, Ghetti B. Abnormal eye movements in Gerstmann-Sträussler-Scheinker disease. Archives of Ophthalmology (Chicago, Ill. : 1960). 110: 68-74. PMID 1731725 DOI: 10.1001/Archopht.1992.01080130070028  1
1992 Ghetti B, Murrell J, Benson MD, Farlow MR. Spectrum of amyloid beta-protein immunoreactivity in hereditary Alzheimer disease with a guanine to thymine missense change at position 1924 of the APP gene. Brain Research. 571: 133-9. PMID 1611485 DOI: 10.1016/0006-8993(92)90519-F  1
1992 Triarhou LC, Low WC, Ghetti B. Intraparenchymal grafting of cerebellar cell suspensions to the deep cerebellar nuclei of pcd mutant mice, with particular emphasis on re-establishment of a Purkinje cell cortico-nuclear projection. Anatomy and Embryology. 185: 409-20. PMID 1567017 DOI: 10.1007/Bf00174079  1
1992 Triarhou LC, Low WC, Ghetti B. Serotonin fiber innervation of cerebellar cell suspensions intraparenchymally grafted to the cerebellum of pcd mutant mice. Neurochemical Research. 17: 475-82. PMID 1528355 DOI: 10.1007/Bf00969895  1
1992 Simon JR, Ghetti B. Topographic distribution of dopamine uptake, choline uptake, choline acetyltransferase, and GABA uptake in the striata of weaver mutant mice. Neurochemical Research. 17: 431-6. PMID 1528352 DOI: 10.1007/Bf00969888  1
1992 Ghetti B, Triarhou LC. Degeneration of mesencephalic dopamine neurons in weaver mutant mice. Neurochemistry International. 20: 305S-307S. PMID 1365447  1
1992 Hsiao K, Dlouhy SR, Farlow MR, Cass C, Da Costa M, Conneally PM, Hodes ME, Ghetti B, Prusiner SB. Mutant prion proteins in Gerstmann-Sträussler-Scheinker disease with neurofibrillary tangles. Nature Genetics. 1: 68-71. PMID 1363810 DOI: 10.1038/Ng0492-68  1
1992 Dlouhy SR, Hsiao K, Farlow MR, Foroud T, Conneally PM, Johnson P, Prusiner SB, Hodes ME, Ghetti B. Linkage of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease to the prion protein gene. Nature Genetics. 1: 64-7. PMID 1363809 DOI: 10.1038/Ng0492-64  1
1992 Giaccone G, Verga L, Bugiani O, Frangione B, Serban D, Prusiner SB, Farlow MR, Ghetti B, Tagliavini F. Prion protein preamyloid and amyloid deposits in Gerstmann-Sträussler-Scheinker disease, Indiana kindred. Proceedings of the National Academy of Sciences of the United States of America. 89: 9349-53. PMID 1357663 DOI: 10.1073/Pnas.89.19.9349  1
1992 Richter JA, Stotz EH, Ghetti B, Simon JR. Comparison of alterations in tyrosine hydroxylase, dopamine levels, and dopamine uptake in the striatum of the weaver mutant mouse. Neurochemical Research. 17: 437-41. PMID 1356243 DOI: 10.1007/Bf00969889  1
1992 Farlow M, Ghetti B, Benson MD, Farrow JS, van Nostrand WE, Wagner SL. Low cerebrospinal-fluid concentrations of soluble amyloid beta-protein precursor in hereditary Alzheimer's disease. Lancet. 340: 453-4. PMID 1354785 DOI: 10.1016/0140-6736(92)91771-Y  1
1991 Bugiani O, Constantinidis J, Ghetti B, Bouras C, Tagliavini F. Asymmetrical cerebral atrophy in Alzheimer's disease. Clinical Neuropathology. 10: 55-60. PMID 2054978  1
1991 Ghetti B, Triarhou LC, Alyea CJ, Dlouhy SR, Karn RC. Unique cerebellar phenotype combining granule and Purkinje cell loss: morphological evidence for weaver* pcd double mutant mice. Journal of Neurocytology. 20: 27-38. PMID 2027034 DOI: 10.1007/Bf01187132  1
1991 Murrell J, Farlow M, Ghetti B, Benson MD. A mutation in the amyloid precursor protein associated with hereditary Alzheimer's disease. Science (New York, N.Y.). 254: 97-9. PMID 1925564 DOI: 10.1126/Science.1925564  1
1991 Simon JR, Yu H, Richter JA, Vasko MR, Ghetti B. In vitro release of endogenous dopamine from the striatum of the weaver mutant mouse. Journal of Neurochemistry. 57: 1478-82. PMID 1919570 DOI: 10.1111/J.1471-4159.1991.Tb06341.X  1
1991 Triarhou LC, Ghetti B. Stabilisation of neurone number in the inferior olivary complex of aged 'Purkinje cell degeneration' mutant mice. Acta Neuropathologica. 81: 597-602. PMID 1882635  1
1991 Triarhou LC, Ghetti B. Serotonin-immunoreactivity in the cerebellum of two neurological mutant mice and the corresponding wild-type genetic stocks. Journal of Chemical Neuroanatomy. 4: 421-8. PMID 1781951  1
1991 Tagliavini F, Prelli F, Ghiso J, Bugiani O, Serban D, Prusiner SB, Farlow MR, Ghetti B, Frangione B. Amyloid protein of Gerstmann-Sträussler-Scheinker disease (Indiana kindred) is an 11 kd fragment of prion protein with an N-terminal glycine at codon 58. The Embo Journal. 10: 513-9. PMID 1672107 DOI: 10.1002/J.1460-2075.1991.Tb07977.X  1
1990 Ghetti B, Triarhou LC, Alyea CJ, Low WC, Chang AC. Timing of neuronal replacement in cerebellar degenerative ataxia of Purkinje cell type. Progress in Brain Research. 82: 197-202. PMID 2290936  1
1990 Triarhou LC, Low WC, Ghetti B. Dopamine neurone grafting to the weaver mouse neostriatum. Progress in Brain Research. 82: 187-95. PMID 2290935  1
1990 Giaccone G, Tagliavini F, Verga L, Frangione B, Farlow MR, Bugiani O, Ghetti B. Neurofibrillary tangles of the Indiana kindred of Gerstmann-Sträussler-Scheinker disease share antigenic determinants with those of Alzheimer disease. Brain Research. 530: 325-9. PMID 2176119 DOI: 10.1016/0006-8993(90)91304-Y  1
1990 Kaseda Y, Ghetti B, Low WC, Norton J, Brittain H, Triarhou LC, Richter JA, Simon JR. Age-related changes in striatal dopamine D2 receptor binding in weaver mice and effects of ventral mesencephalic grafts. Experimental Brain Research. 83: 1-8. PMID 2150046 DOI: 10.1007/Bf00232187  1
1990 Triarhou LC, Brundin P, Doucet G, Norton J, Björklund A, Ghetti B. Intrastriatal implants of mesencephalic cell suspensions in weaver mutant mice: ultrastructural relationships of dopaminergic dendrites and axons issued from the graft. Experimental Brain Research. 79: 3-17. PMID 1968850 DOI: 10.1007/BF00228869  1
1990 Bugiani O, Giaccone G, Verga L, Pollo B, Ghetti B, Frangione B, Tagliavini F. Alzheimer patients and Down patients: abnormal presynaptic terminals are related to cerebral preamyloid deposits. Neuroscience Letters. 119: 56-9. PMID 1965862 DOI: 10.1016/0304-3940(90)90754-W  1
1989 Farlow MR, Yee RD, Dlouhy SR, Conneally PM, Azzarelli B, Ghetti B. Gerstmann-Sträussler-Scheinker disease. I. Extending the clinical spectrum. Neurology. 39: 1446-52. PMID 2812321 DOI: 10.1212/Wnl.39.11.1446  1
1989 Chang AC, Triarhou LC, Alyea CJ, Low WC, Ghetti B. Developmental expression of polypeptide PEP-19 in cerebellar cell suspensions transplanted into the cerebellum of pcd mutant mice. Experimental Brain Research. 76: 639-45. PMID 2792250 DOI: 10.1007/BF00248919  1
1989 Triarhou LC, Ghetti B. The dendritic dopamine projection of the substantia nigra: phenotypic denominator of weaver gene action in hetero- and homozygosity. Brain Research. 501: 373-81. PMID 2573407  1
1989 Ghetti B, Tagliavini F, Masters CL, Beyreuther K, Giaccone G, Verga L, Farlow MR, Conneally PM, Dlouhy SR, Azzarelli B. Gerstmann-Sträussler-Scheinker disease. II. Neurofibrillary tangles and plaques with PrP-amyloid coexist in an affected family. Neurology. 39: 1453-61. PMID 2573006 DOI: 10.1212/Wnl.39.11.1453  1
1989 Doucet G, Brundin P, Seth S, Murata Y, Strecker RE, Triarhou LC, Ghetti B, Björklund A. Degeneration and graft-induced restoration of dopamine innervation in the weaver mouse neostriatum: a quantitative radioautographic study of [3H]dopamine uptake. Experimental Brain Research. 77: 552-68. PMID 2572446 DOI: 10.1007/Bf00249608  1
1989 Bugiani O, Giaccone G, Frangione B, Ghetti B, Tagliavini F. Alzheimer patients: preamyloid deposits are more widely distributed than senile plaques throughout the central nervous system. Neuroscience Letters. 103: 263-8. PMID 2478933 DOI: 10.1016/0304-3940(89)90110-9  1
1988 Triarhou LC, Low WC, Ghetti B. Layer-specific innervation of the dopamine-deficient frontal cortex in weaver mutant mice by grafted mesencephalic dopaminergic neurones. Cell and Tissue Research. 254: 11-5. PMID 2904303  1
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