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Raji E. Joseph, Ph.D. - Publications

Affiliations: 
2004 Iowa State University, Ames, IA, United States 
Area:
Biochemistry
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30 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Kueffer LE, Lin DY, Amatya N, Serrenho J, Joseph RE, Courtney AH, Andreotti AH. Screening and Characterization of Allosteric Small Molecules Targeting Bruton's Tyrosine Kinase. Biochemistry. PMID 38091504 DOI: 10.1021/acs.biochem.3c00362  0.366
2022 Lowe J, Joseph RE, Andreotti AH. Conformational switches that control the TEC kinase - PLCγ signaling axis. Journal of Structural Biology: X. 6: 100061. PMID 35128378 DOI: 10.1016/j.yjsbx.2022.100061  0.334
2021 Kueffer LE, Joseph RE, Andreotti AH. Reining in BTK: Interdomain Interactions and Their Importance in the Regulatory Control of BTK. Frontiers in Cell and Developmental Biology. 9: 655489. PMID 34249912 DOI: 10.3389/fcell.2021.655489  0.317
2020 Joseph RE, Amatya N, Fulton DB, Engen JR, Wales TE, Andreotti A. Differential impact of BTK active site inhibitors on the conformational state of full-length BTK. Elife. 9. PMID 33226337 DOI: 10.7554/eLife.60470  0.359
2019 Amatya N, Wales TE, Kwon A, Yeung W, Joseph RE, Fulton DB, Kannan N, Engen JR, Andreotti AH. Lipid-targeting pleckstrin homology domain turns its autoinhibitory face toward the TEC kinases. Proceedings of the National Academy of Sciences of the United States of America. PMID 31591208 DOI: 10.1073/Pnas.1907566116  0.619
2018 Andreotti AH, Joseph RE, Conley JM, Iwasa J, Berg LJ. Multidomain Control Over TEC Kinase Activation State Tunes the T Cell Response. Annual Review of Immunology. 36: 549-578. PMID 29677469 DOI: 10.1146/Annurev-Immunol-042617-053344  0.538
2017 Joseph RE, Wales TE, Fulton DB, Engen JR, Andreotti AH. Achieving a Graded Immune Response: BTK Adopts a Range of Active/Inactive Conformations Dictated by Multiple Interdomain Contacts. Structure (London, England : 1993). PMID 28867612 DOI: 10.1016/J.Str.2017.07.014  0.516
2017 Devkota S, Joseph RE, Boyken SE, Fulton DB, Andreotti AH. An autoinhibitory role for the Pleckstrin Homology domain of ITK and its interplay with canonical phospholipid recognition. Biochemistry. PMID 28516764 DOI: 10.1021/Acs.Biochem.6B01182  0.582
2016 Chopra N, Wales TE, Joseph RE, Boyken SE, Engen JR, Jernigan RL, Andreotti AH. Dynamic Allostery Mediated by a Conserved Tryptophan in the Tec Family Kinases. Plos Computational Biology. 12: e1004826. PMID 27010561 DOI: 10.1371/Journal.Pcbi.1004826  0.564
2016 Roberts JM, Tarafdar S, Joseph RE, Andreotti AH, Smithgall TE, Engen JR, Wales TE. Dynamics of the Tec-family Tyrosine Kinase SH3 domains. Protein Science : a Publication of the Protein Society. PMID 26808198 DOI: 10.1002/Pro.2887  0.547
2015 Devkota S, Joseph RE, Min L, Bruce Fulton D, Andreotti AH. Scaffold Protein SLP-76 Primes PLCγ1 for Activation by ITK-Mediated Phosphorylation. Journal of Molecular Biology. PMID 25916191 DOI: 10.1016/J.Jmb.2015.04.012  0.596
2014 Boyken SE, Chopra N, Xie Q, Joseph RE, Wales TE, Fulton DB, Engen JR, Jernigan RL, Andreotti AH. A conserved isoleucine maintains the inactive state of Bruton's tyrosine kinase. Journal of Molecular Biology. 426: 3656-69. PMID 25193673 DOI: 10.1016/J.Jmb.2014.08.018  0.62
2013 Joseph RE, Kleino I, Wales TE, Xie Q, Fulton DB, Engen JR, Berg LJ, Andreotti AH. Activation loop dynamics determine the different catalytic efficiencies of B cell- and T cell-specific tec kinases. Science Signaling. 6: ra76. PMID 23982207 DOI: 10.1126/Scisignal.2004298  0.517
2013 Xie Q, Joseph RE, Fulton DB, Andreotti AH. Substrate recognition of PLCγ1 via a specific docking surface on Itk. Journal of Molecular Biology. 425: 683-96. PMID 23219468 DOI: 10.1016/J.Jmb.2012.10.023  0.597
2012 Joseph RE, Ginder ND, Hoy JA, Nix JC, Fulton DB, Honzatko RB, Andreotti AH. Structure of the interleukin-2 tyrosine kinase Src homology 2 domain; comparison between X-ray and NMR-derived structures. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 68: 145-53. PMID 22297986 DOI: 10.1107/S1744309111049761  0.473
2011 Joseph RE, Ginder ND, Hoy JA, Nix JC, Honzatko RB, Andreotti AH. Purification, crystallization and preliminary crystallographic analysis of the SH2 domain of IL-2-inducible T-cell kinase. Acta Crystallographica. Section F, Structural Biology and Crystallization Communications. 67: 269-73. PMID 21301103 DOI: 10.1107/S1744309110052346  0.444
2011 Joseph RE, Andreotti AH. Controlling the activity of the Tec kinase Itk by mutation of the phenylalanine gatekeeper residue. Biochemistry. 50: 221-9. PMID 21138328 DOI: 10.1021/Bi101379M  0.526
2010 Joseph RE, Xie Q, Andreotti AH. Identification of an allosteric signaling network within Tec family kinases. Journal of Molecular Biology. 403: 231-42. PMID 20826165 DOI: 10.1016/J.Jmb.2010.08.035  0.594
2010 Andreotti AH, Schwartzberg PL, Joseph RE, Berg LJ. T-cell signaling regulated by the Tec family kinase, Itk. Cold Spring Harbor Perspectives in Biology. 2: a002287. PMID 20519342 DOI: 10.1101/Cshperspect.A002287  0.432
2010 Min L, Wu W, Joseph RE, Fulton DB, Berg L, Andreotti AH. Disrupting the intermolecular self-association of Itk enhances T cell signaling. Journal of Immunology (Baltimore, Md. : 1950). 184: 4228-35. PMID 20237289 DOI: 10.4049/Jimmunol.0901908  0.527
2009 Min L, Joseph RE, Fulton DB, Andreotti AH. Itk tyrosine kinase substrate docking is mediated by a nonclassical SH2 domain surface of PLCgamma1. Proceedings of the National Academy of Sciences of the United States of America. 106: 21143-8. PMID 19955438 DOI: 10.1073/Pnas.0911309106  0.611
2009 Joseph RE, Severin A, Min L, Fulton DB, Andreotti AH. SH2-dependent autophosphorylation within the Tec family kinase Itk. Journal of Molecular Biology. 391: 164-77. PMID 19523959 DOI: 10.1016/J.Jmb.2009.06.023  0.628
2009 Severin A, Joseph RE, Boyken S, Fulton DB, Andreotti AH. Proline isomerization preorganizes the Itk SH2 domain for binding to the Itk SH3 domain. Journal of Molecular Biology. 387: 726-43. PMID 19361414 DOI: 10.1016/J.Jmb.2009.02.012  0.527
2009 Joseph RE, Andreotti AH. Conformational snapshots of Tec kinases during signaling. Immunological Reviews. 228: 74-92. PMID 19290922 DOI: 10.1111/J.1600-065X.2008.00740.X  0.484
2008 Joseph RE, Andreotti AH. Bacterial expression and purification of interleukin-2 tyrosine kinase: single step separation of the chaperonin impurity. Protein Expression and Purification. 60: 194-7. PMID 18495488 DOI: 10.1016/J.Pep.2008.04.001  0.459
2007 Joseph RE, Fulton DB, Andreotti AH. Mechanism and functional significance of Itk autophosphorylation. Journal of Molecular Biology. 373: 1281-92. PMID 17897671 DOI: 10.1016/J.Jmb.2007.08.060  0.566
2007 Joseph RE, Min L, Xu R, Musselman ED, Andreotti AH. A remote substrate docking mechanism for the tec family tyrosine kinases. Biochemistry. 46: 5595-603. PMID 17439160 DOI: 10.1021/Bi700127C  0.611
2007 Joseph RE, Min L, Andreotti AH. The linker between SH2 and kinase domains positively regulates catalysis of the Tec family kinases. Biochemistry. 46: 5455-62. PMID 17425330 DOI: 10.1021/Bi602512E  0.56
2005 Joseph RE, Norris FA. Substrate specificity and recognition is conferred by the pleckstrin homology domain of the Dbl family guanine nucleotide exchange factor P-Rex2. The Journal of Biological Chemistry. 280: 27508-12. PMID 15897194 DOI: 10.1074/Jbc.M412495200  0.587
1999 Joseph RE, Walker J, Norris FA. Assignment of the inositol polyphosphate 4-phosphatase type I gene (INPP4A) to human chromosome band 2q11.2 by in situ hybridization. Cytogenetics and Cell Genetics. 87: 276-7. PMID 10702694  0.45
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