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Philip W. Wertz - Publications

Affiliations: 
University of Iowa, Iowa City, IA 
Area:
Biochemistry
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117 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Wertz PW. LINOLEATE-CONTAINING ACYLGLUCOSYLCERAMIDE, ACYLCERAMIDE AND EVENTS ASSOCIATED WITH FORMATION OF THE EPIDERMAL PERMEABILITY BARRIER. Skin Pharmacology and Physiology. PMID 38035548 DOI: 10.1159/000535049  0.323
2021 Wertz PW. Roles of Lipids in the Permeability Barriers of Skin and Oral Mucosa. International Journal of Molecular Sciences. 22. PMID 34063352 DOI: 10.3390/ijms22105229  0.419
2021 Wertz PW. Lipid Metabolic Events Underlying the Formation of the Corneocyte Lipid Envelope. Skin Pharmacology and Physiology. 34: 38-50. PMID 33567435 DOI: 10.1159/000513261  0.39
2020 Wertz PW, Szalay Sd. Innate Antimicrobial Defense of Skin and Oral Mucosa. The Journal of Antibiotics. 9: 159. PMID 32260154 DOI: 10.3390/Antibiotics9040159  0.383
2018 Wertz PW. Lipids and the Permeability and Antimicrobial Barriers of the Skin. Journal of Lipids. 2018: 5954034. PMID 30245886 DOI: 10.1155/2018/5954034  0.526
2018 Wertz P. Epidermal Lamellar Granules. Skin Pharmacology and Physiology. 31: 262-268. PMID 30110701 DOI: 10.1159/000491757  0.436
2015 Fischer CL, Dawson DV, Blanchette DR, Drake DR, Wertz PW, Brogden KA. Protein Analysis of Sapienic Acid-Treated Porphyromonas gingivalis Suggests Differential Regulation of Multiple Metabolic Pathways. Journal of Bacteriology. 198: 157-67. PMID 26483519 DOI: 10.1128/Jb.00665-15  0.397
2015 Poulsen C, Mehalick LA, Fischer CL, Lanzel EA, Bates AM, Walters KS, Cavanaugh JE, Guthmiller JM, Johnson GK, Wertz PW, Brogden KA. Differential cytotoxicity of long-chain bases for human oral gingival epithelial keratinocytes, oral fibroblasts, and dendritic cells. Toxicology Letters. 237: 21-9. PMID 26005054 DOI: 10.1016/J.Toxlet.2015.05.012  0.302
2014 Fischer CL, Blanchette DR, Brogden KA, Dawson DV, Drake DR, Hill JR, Wertz PW. The roles of cutaneous lipids in host defense. Biochimica Et Biophysica Acta. 1841: 319-22. PMID 23994607 DOI: 10.1016/J.Bbalip.2013.08.012  0.455
2013 Wertz PW. Current Understanding of Skin Biology Pertinent to Skin Penetration: Skin Biochemistry Skin Pharmacology and Physiology. 26: 217-226. PMID 23921108 DOI: 10.1159/000351949  0.393
2013 Fischer CL, Walters KS, Drake DR, Dawson DV, Blanchette DR, Brogden KA, Wertz PW. Oral mucosal lipids are antibacterial against Porphyromonas gingivalis, induce ultrastructural damage, and alter bacterial lipid and protein compositions. International Journal of Oral Science. 5: 130-40. PMID 23867843 DOI: 10.1038/Ijos.2013.28  0.477
2013 Dawson DV, Drake DR, Hill JR, Brogden KA, Fischer CL, Wertz PW. Organization, barrier function and antimicrobial lipids of the oral mucosa. International Journal of Cosmetic Science. 35: 220-3. PMID 23320785 DOI: 10.1111/Ics.12038  0.375
2013 Fischer CL, Walters KS, Drake DR, Blanchette DR, Dawson DV, Brogden KA, Wertz PW. Sphingoid bases are taken up by Escherichia coli and Staphylococcus aureus and induce ultrastructural damage. Skin Pharmacology and Physiology. 26: 36-44. PMID 23128426 DOI: 10.1159/000343175  0.316
2012 Brogden NK, Mehalick L, Fischer CL, Wertz PW, Brogden KA. The emerging role of peptides and lipids as antimicrobial epidermal barriers and modulators of local inflammation. Skin Pharmacology and Physiology. 25: 167-81. PMID 22538862 DOI: 10.1159/000337927  0.361
2012 Fischer CL, Drake DR, Dawson DV, Blanchette DR, Brogden KA, Wertz PW. Antibacterial activity of sphingoid bases and fatty acids against Gram-positive and Gram-negative bacteria. Antimicrobial Agents and Chemotherapy. 56: 1157-61. PMID 22155833 DOI: 10.1128/Aac.05151-11  0.409
2011 Brasser AJ, Barwacz CA, Dawson DV, Brogden KA, Drake DR, Wertz PW. Presence of wax esters and squalene in human saliva. Archives of Oral Biology. 56: 588-91. PMID 21247555 DOI: 10.1016/J.Archoralbio.2010.12.002  0.38
2010 Valacchi G, De Luca C, Wertz PW. Lipid mediators in skin inflammation: updates and current views. Mediators of Inflammation. 2010: 398926. PMID 20981239 DOI: 10.1155/2010/398926  0.313
2010 Stefaniak AB, Harvey CJ, Wertz PW. Formulation and stability of a novel artificial sebum under conditions of storage and use. International Journal of Cosmetic Science. 32: 347-55. PMID 20491993 DOI: 10.1111/J.1468-2494.2010.00561.X  0.423
2009 Reiter LV, Torres SMF, Wertz PW. Characterization and quantification of ceramides in the nonlesional skin of canine patients with atopic dermatitis compared with controls. Veterinary Dermatology. 20: 260-266. PMID 19659537 DOI: 10.1111/J.1365-3164.2009.00759.X  0.356
2009 Hayden PJ, Petrali JP, Stolper G, Hamilton TA, Jackson GR, Wertz PW, Ito S, Smith WJ, Klausner M. Microvesicating effects of sulfur mustard on an in vitro human skin model. Toxicology in Vitro : An International Journal Published in Association With Bibra. 23: 1396-405. PMID 19619636 DOI: 10.1016/J.Tiv.2009.07.021  0.382
2009 Batheja P, Song Y, Wertz P, Michniak-Kohn B. Effects of growth conditions on the barrier properties of a human skin equivalent. Pharmaceutical Research. 26: 1689-700. PMID 19415472 DOI: 10.1007/S11095-009-9879-1  0.343
2009 Hill JR, Wertz PW. Structures of the ceramides from porcine palatal stratum corneum. Lipids. 44: 291-5. PMID 19184160 DOI: 10.1007/S11745-009-3283-9  0.416
2009 Wertz PW. Human synthetic sebum formulation and stability under conditions of use and storage. International Journal of Cosmetic Science. 31: 21-25. PMID 19134124 DOI: 10.1111/J.1468-2494.2008.00468.X  0.446
2008 Pappinen S, Hermansson M, Kuntsche J, Somerharju P, Wertz P, Urtti A, Suhonen M. Comparison of rat epidermal keratinocyte organotypic culture (ROC) with intact human skin: lipid composition and thermal phase behavior of the stratum corneum. Biochimica Et Biophysica Acta. 1778: 824-34. PMID 18211819 DOI: 10.1016/J.Bbamem.2007.12.019  0.477
2008 Drake DR, Brogden KA, Dawson DV, Wertz PW. Thematic review series: skin lipids. Antimicrobial lipids at the skin surface. Journal of Lipid Research. 49: 4-11. PMID 17906220 DOI: 10.1194/Jlr.R700016-Jlr200  0.456
2007 López O, Cócera M, Wertz PW, López-Iglesias C, Maza Adl. New arrangement of proteins and lipids in the stratum corneum cornified envelope. Biochimica Et Biophysica Acta. 1768: 521-529. PMID 17292323 DOI: 10.1016/J.Bbamem.2006.11.023  0.421
2006 Hill J, Paslin D, Wertz PW. A new covalently bound ceramide from human stratum corneum –ω‐hydroxyacylphytosphingosine International Journal of Cosmetic Science. 28: 225-230. PMID 18489279 DOI: 10.1111/J.1467-2494.2006.00324.X  0.359
2006 de Guzman Strong C, Wertz PW, Wang C, Yang F, Meltzer PS, Andl T, Millar SE, Ho IC, Pai SY, Segre JA. Lipid defect underlies selective skin barrier impairment of an epidermal-specific deletion of Gata-3. The Journal of Cell Biology. 175: 661-70. PMID 17116754 DOI: 10.1083/Jcb.200605057  0.415
2006 Yu Z, Lin KK, Bhandari A, Spencer JA, Xu X, Wang N, Lu Z, Gill GN, Roop DR, Wertz P, Andersen B. The Grainyhead-like epithelial transactivator Get-1/Grhl3 regulates epidermal terminal differentiation and interacts functionally with LMO4. Developmental Biology. 299: 122-36. PMID 16949565 DOI: 10.1016/J.Ydbio.2006.07.015  0.344
2005 Duvel L, Chun H, Deppa D, Wertz PW. Analysis of hair lipids and tensile properties as a function of distance from scalp International Journal of Cosmetic Science. 27: 193-197. PMID 18492187 DOI: 10.1111/J.1467-2494.2005.00236.X  0.495
2004 Gasparoni A, Fonzi L, Schneider GB, Wertz PW, Johnson GK, Squier CA. Comparison of differentiation markers between normal and two squamous cell carcinoma cell lines in culture Archives of Oral Biology. 49: 653-664. PMID 15196983 DOI: 10.1016/J.Archoralbio.2004.02.010  0.317
2003 Haugen M, Williams JB, Wertz P, Tieleman BI. Lipids of the stratum corneum vary with cutaneous water loss among larks along a temperature-moisture gradient. Physiological and Biochemical Zoology : Pbz. 76: 907-17. PMID 14988806 DOI: 10.1086/380213  0.365
2003 Squier CA, Kremer MJ, Wertz PW. Effect of ethanol on lipid metabolism and epithelial permeability barrier of skin and oral mucosa in the rat Journal of Oral Pathology & Medicine. 32: 595-599. PMID 14632934 DOI: 10.1034/J.1600-0714.2003.00198.X  0.403
2003 Hill JR, Wertz PW. Molecular models of the intercellular lipid lamellae from epidermal stratum corneum. Biochimica Et Biophysica Acta. 1616: 121-6. PMID 14561469 DOI: 10.1016/S0005-2736(03)00238-4  0.319
2003 Bánóczy J, Squier CA, Kremer M, Wertz PW, Kövesi G, Szende B, Dombi C. The permeability of oral leukoplakia. European Journal of Oral Sciences. 111: 312-315. PMID 12887396 DOI: 10.1034/J.1600-0722.2003.00042.X  0.381
2003 Fluhr JW, Mao-Qiang M, Brown BE, Wertz PW, Crumrine D, Sundberg JP, Feingold KR, Elias PM. Glycerol regulates stratum corneum hydration in sebaceous gland deficient (asebia) mice. The Journal of Investigative Dermatology. 120: 728-37. PMID 12713573 DOI: 10.1046/J.1523-1747.2003.12134.X  0.414
2003 Sando GN, Zhu H, Weis JM, Richman JT, Wertz PW, Madison KC. Caveolin expression and localization in human keratinocytes suggest a role in lamellar granule biogenesis. The Journal of Investigative Dermatology. 120: 531-41. PMID 12648214 DOI: 10.1046/J.1523-1747.2003.12051.X  0.381
2003 Chinnathambi S, Tomanek-Chalkley A, Ludwig N, King E, DeWaard R, Johnson G, Wertz PW, Bickenbach JR. Recapitulation of oral mucosal tissues in long-term organotypic culture. The Anatomical Record. Part a, Discoveries in Molecular, Cellular, and Evolutionary Biology. 270: 162-74. PMID 12524691 DOI: 10.1002/Ar.A.10021  0.387
2001 Monteiro-Riviere NA, Inman AO, Mak V, Wertz P, Riviere JE. Effect of selective lipid extraction from different body regions on epidermal barrier function Pharmaceutical Research. 18: 992-998. PMID 11496960 DOI: 10.1023/A:1010944529387  0.406
2001 Van Den Bergh BAI, Wertz PW, Junginger HE, Bouwstra JA. Elasticity of vesicles assessed by electron spin resonance, electron microscopy and extrusion measurements International Journal of Pharmaceutics. 217: 13-24. PMID 11292538 DOI: 10.1016/S0378-5173(01)00576-2  0.361
2001 Asbill C, Kim N, El-Kattan A, Creek K, Wertz P, Michniak B. Evaluation of a human bio-engineered skin equivalent for drug permeation studies. Pharmaceutical Research. 17: 1092-7. PMID 11087041 DOI: 10.1023/A:1026405712870  0.362
2000 Wertz PW. Lipids and barrier function of the skin. Acta Dermato-Venereologica. 208: 7-11. PMID 10884933 DOI: 10.1080/000155500750042790  0.507
1999 Van Den Bergh BAI, Bouwstra JA, Junginger HE, Wertz PW. Elasticity of vesicles affects hairless mouse skin structure and permeability Journal of Controlled Release. 62: 367-379. PMID 10528074 DOI: 10.1016/S0168-3659(99)00168-6  0.403
1998 Madison KC, Sando GN, Howard EJ, True CA, Gilbert D, Swartzendruber DC, Wertz PW. Lamellar granule biogenesis: a role for ceramide glucosyltransferase, lysosomal enzyme transport, and the Golgi. The Journal of Investigative Dermatology. Symposium Proceedings / the Society For Investigative Dermatology, Inc. [and] European Society For Dermatological Research. 3: 80-6. PMID 9734819 DOI: 10.1038/Jidsymp.1998.19  0.383
1998 Kuempel D, Swartzendruber DC, Squier CA, Wertz PW. In vitro reconstitution of stratum corneum lipid lamellae. Biochimica Et Biophysica Acta. 1372: 135-140. PMID 9651505 DOI: 10.1016/S0005-2736(98)00053-4  0.377
1998 Wertz PW, Bergh Bvd. The physical, chemical and functional properties of lipids in the skin and other biological barriers Chemistry and Physics of Lipids. 91: 85-96. PMID 9569614 DOI: 10.1016/S0009-3084(97)00108-4  0.415
1998 Nardo AD, Wertz P, Giannetti A, Seidenari S. Ceramide and cholesterol composition of the skin of patients with atopic dermatitis. Acta Dermato-Venereologica. 78: 27-30. PMID 9498022 DOI: 10.1080/00015559850135788  0.393
1997 Whittle S, Swartzendruber DC, Kremer M, Squier CA, Wertz PW. Lipids of hamster cheek pouch epithelium. Lipids. 32: 961-964. PMID 9307937 DOI: 10.1007/S11745-997-0124-Y  0.507
1997 Attar PS, Wertz PW, McArthur M, Imakado S, Bickenbach JR, Roop DR. Inhibition of retinoid signaling in transgenic mice alters lipid processing and disrupts epidermal barrier function. Molecular Endocrinology (Baltimore, Md.). 11: 792-800. PMID 9171242 DOI: 10.1210/Mend.11.6.0010  0.34
1997 Squier CA, Kremer M, Wertz PW. Continuous flow mucosal cells for measuring the in‐vitro permeability of small tissue samples Journal of Pharmaceutical Sciences. 86: 82-84. PMID 9002464 DOI: 10.1021/Js9602047  0.304
1996 Di Nardo A, Sugino K, Wertz P, Ademola J, Maibach HI. Sodium lauryl sulfate (SLS) induced irritant contact dermatitis: A correlation study between ceramides and in vivo parameters of irritation Contact Dermatitis. 35: 86-91. PMID 8917825 DOI: 10.1111/J.1600-0536.1996.Tb02296.X  0.373
1996 Manganaro AM, Wertz PW. The effects of permeabilizers on the in vitro penetration of propranolol through porcine buccal epithelium Military Medicine. 161: 669-672. DOI: 10.1093/Milmed/161.11.669  0.343
1996 Wertz PW. The nature of the epidermal barrier: biochemical aspects Advanced Drug Delivery Reviews. 18: 283-294. DOI: 10.1016/0169-409X(95)00077-K  0.493
1995 Law S, Wertz PW, Swartzendruber DC, Squier CA. Regional variation in content, composition and organization of porcine epithelial barrier lipids revealed by thin-layer chromatography and transmission electron microscopy Archives of Oral Biology. 40: 1085-1091. PMID 8850646 DOI: 10.1016/0003-9969(95)00091-7  0.46
1995 Swartzendruber DC, Burnett IH, Wertz PW, Madison KC, Squier CA. Osmium tetroxide and ruthenium tetroxide are complementary reagents for the preparation of epidermal samples for transmission electron microscopy. Journal of Investigative Dermatology. 104: 417-420. PMID 7861011 DOI: 10.1111/1523-1747.Ep12665909  0.413
1995 Swartzendruber DC, Manganaro A, Madison KC, Kremer M, Wertz PW, Squier CA. Organization of the intercellular spaces of porcine epidermal and palatal stratum corneum: a quantitative study employing ruthenium tetroxide. Cell and Tissue Research. 279: 271-276. PMID 7534652 DOI: 10.1007/Bf00318483  0.354
1994 Wertz PW. Lipids: Molecular organization, physical functions and technical applications: by Kåre Larsson, Oily Press, Dundee, 1994, 237 pages, $55 U.S. Chemistry and Physics of Lipids. 74: 99-100. DOI: 10.1016/0009-3084(94)90116-3  0.32
1993 Abrams K, Harvell JD, Shriner D, Wertz P, Maibach H, Maibach HI, Rehfeld SJ. Effect of organic solvents on in vitro human skin water barrier function Journal of Investigative Dermatology. 101: 609-613. PMID 8409532 DOI: 10.1111/1523-1747.Ep12366068  0.44
1993 Chang F, Swartzendruber DC, Wertz PW, Squier CA. Covalently bound lipids in keratinizing epithelia Biochimica Et Biophysica Acta. 1150: 98-102. PMID 8334143 DOI: 10.1016/0005-2736(93)90126-K  0.52
1993 Squier CA, Wertz PW. Permeability and the pathophysiology of oral mucosa Advanced Drug Delivery Reviews. 12: 13-24. DOI: 10.1016/0169-409X(93)90038-6  0.326
1993 Wertz PW, Swartzendruber DC, Squier CA. Regional variation in the structure and permeability of oral mucosa and skin Advanced Drug Delivery Reviews. 12: 1-12. DOI: 10.1016/0169-409X(93)90037-5  0.482
1992 Wertz PW, Kremer M, Squier CA. Comparison of lipids from epidermal and palatal stratum corneum. Journal of Investigative Dermatology. 98: 375-378. PMID 1545146 DOI: 10.1111/1523-1747.Ep12499809  0.49
1991 Squier CA, Cox P, Wertz PW. Lipid Content and Water Permeability of Skin and Oral Mucosa Journal of Investigative Dermatology. 96: 123-126. PMID 1987287 DOI: 10.1111/1523-1747.Ep12515931  0.498
1991 Squier CA, Wertz PW, Cox P. Thin-layer chromatographic analyses of lipids in different layers of porcine epidermis and oral epithelium Archives of Oral Biology. 36: 647-653. PMID 1741696 DOI: 10.1016/0003-9969(91)90017-O  0.463
1990 Wertz PW, Downing DT. Free Sphingosine in Human Epidermis Journal of Investigative Dermatology. 94: 159-161. PMID 2299191 DOI: 10.1111/1523-1747.Ep12874122  0.371
1990 Bortz JT, Wertz PW, Downing DT. Composition of cerumen lipids Journal of the American Academy of Dermatology. 23: 845-849. PMID 2254469 DOI: 10.1016/0190-9622(90)70301-W  0.51
1990 Madison KC, Swartzendruber DC, Wertz PW, Downing DT. Sphingolipid metabolism in organotypic mouse keratinocyte cultures Journal of Investigative Dermatology. 95: 657-664. PMID 2123494 DOI: 10.1111/1523-1747.Ep12514333  0.419
1990 Wertz PW, Downing DT. Metabolism of topically applied fatty acid methyl esters in BALB/C mouse epidermis. Journal of Dermatological Science. 1: 33-37. PMID 2078539 DOI: 10.1016/0923-1811(90)90007-Z  0.425
1989 Wertz PW, Downing DT. Free sphingosines in porcine epidermis. Biochimica Et Biophysica Acta. 1002: 213-217. PMID 2930769 DOI: 10.1016/0005-2760(89)90289-0  0.392
1989 Wertz PW, Downing DT, Swartzendruber DC, Madison KC, Strauss JS. Membrane structural alterations in murine stratum corneum: Relationship to the localization of polar lipids and phospholipases Journal of Investigative Dermatology. 92: 305. PMID 2918238 DOI: 10.1111/1523-1747.Ep12277017  0.383
1989 Swartzendruber DC, Wertz PW, Kitko DJ, Madison KC, Downing DT. Molecular models of the Intercellular Lipid Lamellae in Mammalian Stratum Corneum Journal of Investigative Dermatology. 92: 251-257. PMID 2918233 DOI: 10.1111/1523-1747.Ep12276794  0.489
1989 Wertz PW, Swartzendruber DC, Kitko DJ, Madison KC, Downing DT. The role of the corneocyte lipid envelopes in cohesion of the stratum corneum. Journal of Investigative Dermatology. 93: 169-172. PMID 2746002 DOI: 10.1111/1523-1747.Ep12277394  0.422
1989 Wertz PW, Downing DT. Integral lipids of mammalian hair. Comparative Biochemistry and Physiology B. 92: 759-761. PMID 2721159 DOI: 10.1016/0305-0491(89)90264-2  0.418
1989 Bortz JT, Wertz PW, Downing DT. The origin of alkanes found in human skin surface lipids Journal of Investigative Dermatology. 93: 723-727. PMID 2584738 DOI: 10.1111/1523-1747.Ep12284393  0.431
1989 Madison KC, Swartzendruber DC, Wertz PW, Downing DT. Murine keratinocyte cultures grown at the air/medium interface synthesize stratum corneum lipids and "recycle" linoleate during differentiation. Journal of Investigative Dermatology. 93: 10-17. PMID 2473131 DOI: 10.1111/1523-1747.Ep12277335  0.436
1988 Wertz PW, Downing DT. Hydroxyacid derivatives in human epidermis. Lipids. 23: 415-418. PMID 3412119 DOI: 10.1007/Bf02535512  0.489
1988 Hedberg CL, Wertz PW, Downing DT. The time course of lipid biosynthesis in pig epidermis Journal of Investigative Dermatology. 91: 169-174. PMID 3397589 DOI: 10.1111/1523-1747.Ep12464438  0.397
1988 Abraham W, Wertz PW, Downing DT. Effect of epidermal acylglucosylceramides and acylceramides on the morphology of liposomes prepared from stratum corneum lipids. Biochimica Et Biophysica Acta. 939: 403-408. PMID 3355824 DOI: 10.1016/0005-2736(88)90086-7  0.476
1988 Abraham W, Wertz PW, Downing DT. Fusion patterns of liposomes formed from stratum corneum lipids Journal of Investigative Dermatology. 90: 259-262. PMID 3346554 DOI: 10.1111/1523-1747.Ep12455865  0.444
1988 Hedberg CL, Wertz PW, Downing DT. The nonpolar lipids of pig epidermis Journal of Investigative Dermatology. 90: 225-229. PMID 3339264 DOI: 10.1111/1523-1747.Ep12462257  0.457
1988 Swartzendruber DC, Kitko DJ, Wertz PW, Madison KC, Downing DT. Isolation of corneocyte envelopes from porcine epidermis. Archives of Dermatological Research. 280: 424-429. PMID 3207369 DOI: 10.1007/Bf00429982  0.328
1988 Wertz PW, Downing DT. Integral lipids of human hair. Lipids. 23: 878-881. PMID 3185123 DOI: 10.1007/Bf02536208  0.444
1988 Perisho K, Wertz PW, Madison KC, Stewart ME, Downing DT. Fatty acids of acylceramides from comedones and from the skin surface of acne patients and control subjects Journal of Investigative Dermatology. 90: 350-353. PMID 2964492 DOI: 10.1111/1523-1747.Ep12456327  0.456
1988 Madison KC, Swartzendruber DC, Wertz PW, Downing DT. Lamellar granule extrusion and stratum corneum intercellular lamellae in murine keratinocyte cultures. Journal of Investigative Dermatology. 90: 110-116. PMID 2448389 DOI: 10.1111/1523-1747.Ep12462065  0.424
1987 Abraham W, Wertz PW, Landmann L, Downing DT. Stratum corneum lipid liposomes: Calcium-induced transformation into lamellar sheets Journal of Investigative Dermatology. 88: 212-214. PMID 3805757 DOI: 10.1111/1523-1747.Ep12525375  0.455
1987 Wertz PW, Downing DT. Covalently bound ω-hydroxyacylsphingosine in the stratum corneum Biochimica Et Biophysica Acta. 917: 108-111. PMID 3790600 DOI: 10.1016/0005-2760(87)90290-6  0.446
1987 Wertz PW, Schwartzendruber DC, Madison KC, Downing DT. Composition and morphology of epidermal cyst lipids. Journal of Investigative Dermatology. 89: 419-425. PMID 3668284 DOI: 10.1111/1523-1747.Ep12471781  0.509
1987 Melton JL, Wertz PW, Swartzendruber DC, Downing DT. Effects of essential fatty acid deficiency on epidermal O-acylsphingolipids and transepidermal water loss in young pigs Biochimica Et Biophysica Acta. 921: 191-197. PMID 3651483 DOI: 10.1016/0005-2760(87)90018-X  0.419
1987 Madison KC, Swartzendruber DC, Wertz PW, Downing DT. Presence of intact intercellular lipid lamellae in the upper layers of the stratum corneum Journal of Investigative Dermatology. 88: 714-718. PMID 3585055 DOI: 10.1111/1523-1747.Ep12470386  0.466
1987 Swartzendruber DC, Wertz PW, Madison KC, Downing DT. Evidence That the Corneocyte Has a Chemically Bound Lipid Envelope Journal of Investigative Dermatology. 88: 709-713. PMID 3585054 DOI: 10.1111/1523-1747.Ep12470383  0.501
1987 Wix MA, Wertz PW, Downing DT. Polar lipid composition of mammalian hair Comparative Biochemistry and Physiology B. 86: 671-673. PMID 3581794 DOI: 10.1016/0305-0491(87)90208-2  0.44
1987 Downing DT, Stewart ME, Wertz PW, Colton SW, Abraham W, Strauss JS. Skin Lipids: An Update Journal of Investigative Dermatology. 88: 2-6. DOI: 10.1038/Jid.1987.2  0.516
1987 Wertz PW, Swartzendruber DC, Abraham W, Madison KC, Downing DT. Essential fatty acids and epidermal integrity. Archives of Dermatology. 123: 1381-1384. DOI: 10.1001/Archderm.1987.01660340149038  0.474
1986 Downing DT, Wertz PW, Stewart ME. The role of sebum and epidermal lipids in the cosmetic properties of skin. International Journal of Cosmetic Science. 8: 115-123. PMID 19460047 DOI: 10.1111/J.1467-2494.1986.Tb00439.X  0.484
1986 Wertz PW, Abraham W, Landmann L, Downing DT. Preparation of liposomes from stratum corneum lipids Journal of Investigative Dermatology. 87: 582-584. PMID 3772151 DOI: 10.1111/1523-1747.Ep12455832  0.499
1986 Merrill AH, Wang E, Wertz PW. Differences in the long chain (sphingoid) base composition of sphingomyelin from rats bearing Morris hepatoma 7777 Lipids. 21: 529-530. PMID 3762323 DOI: 10.1007/Bf02535642  0.312
1986 Ranasinghe AW, Wertz PW, Downing DT, Mackenzie IC. Lipid composition of cohesive and desquamated corneocytes from mouse ear skin. Journal of Investigative Dermatology. 86: 187-190. PMID 3745944 DOI: 10.1111/1523-1747.Ep12284246  0.474
1986 Wertz PW, Downing DT. Covalent attachment of ω-hydroxyacid derivatives to epidermal macromolecules: A preliminary characterization Biochemical and Biophysical Research Communications. 137: 992-997. PMID 3729963 DOI: 10.1016/0006-291X(86)90323-2  0.472
1986 Wertz PW, Downing DT. Linoleate content of epidermal acylglucosylceramide in newborn, growing and mature mice Biochimica Et Biophysica Acta. 876: 469-473. PMID 3707979 DOI: 10.1016/0005-2760(86)90033-0  0.4
1986 Wertz PW, Stover PM, Downing DT. A survey of polar and nonpolar lipids from epidermis and epidermal appendages of the chicken (Gallus domesticus) Comparative Biochemistry and Physiology B. 84: 203-206. PMID 3524982 DOI: 10.1016/0305-0491(86)90206-3  0.492
1986 Madison KC, Wertz PW, Strauss JS, Downing DT. Lipid composition of cultured murine keratinocytes. Journal of Investigative Dermatology. 87: 253-259. PMID 3090156 DOI: 10.1111/1523-1747.Ep12696636  0.468
1986 Stewart ME, Grahek MO, Cambier LS, Wertz PW, Downing DT. Dilutional effect of increased sebaceous gland activity on the proportion of linoleic acid in sebaceous wax esters and in epidermal acylceramides. The Journal of Investigative Dermatology. 87: 733-6. PMID 2946783 DOI: 10.1111/1523-1747.Ep12456856  0.406
1986 Downing DT, Stewart ME, Wertz PW, Strauss JS. Essential fatty acids and acne Journal of the American Academy of Dermatology. 14: 221-225. PMID 2936775 DOI: 10.1016/S0190-9622(86)70025-X  0.427
1986 Squier CA, Cox PS, Wertz PW, Downing DT. The lipid composition of porcine epidermis and oral epithelium. Archives of Oral Biology. 31: 741-747. PMID 2445322 DOI: 10.1016/0003-9969(86)90006-3  0.509
1986 Wertz PW, Cox PS, Squier CA, Downing DT. Lipids of epidermis and keratinized and non-keratinized oral epithelia. Comparative Biochemistry and Physiology B. 83: 529-531. PMID 2420526 DOI: 10.1016/0305-0491(86)90291-9  0.433
1986 Wertz PW, Abraham W, Cho ES, Downing DT. Linoleate-rich O-acylsphingolipids of mammalian epidermis: Structures and effects of essential fatty acid deficiency Progress in Lipid Research. 25: 383-389. DOI: 10.1016/0163-7827(86)90077-9  0.322
1985 Schoephoerster RT, Wertz PW, Madison KC, Downing DT. A survey of polar and non-polar lipids of mouse organs. Comparative Biochemistry and Physiology. B, Comparative Biochemistry. 82: 229-32. PMID 4053583 DOI: 10.1016/0305-0491(85)90231-7  0.438
1985 Burken RR, Wertz PW, Downing DT. A survey of polar and nonpolar lipids extracted from snake skin Comparative Biochemistry and Physiology B. 81: 315-318. PMID 4017551 DOI: 10.1016/0305-0491(85)90319-0  0.505
1985 Long SA, Wertz PW, Strauss JS, Downing DT. Human stratum corneum polar lipids and desquamation Archives of Dermatological Research. 277: 284-287. PMID 4004327 DOI: 10.1007/Bf00509081  0.379
1985 Wertz PW, Miethke MC, Long SA, Strauss JS, Downing DT. The composition of the ceramides from human stratum corneum and from comedones Journal of Investigative Dermatology. 84: 410-412. PMID 3158712 DOI: 10.1111/1523-1747.Ep12265510  0.431
1985 Burken RR, Wertz PW, Downing DT. The effect of lipids on transepidermal water permeation in snakes. Comparative Biochemistry and Physiology Part a: Physiology. 81: 213-216. PMID 2864162 DOI: 10.1016/0300-9629(85)90124-0  0.388
1984 Landmann L, Wertz PW, Downing DT. Acylglucosylceramide causes flattening and stacking of liposomes. An analogy for assembly of the epidermal permeability barrier Biochimica Et Biophysica Acta. 778: 412-418. PMID 6509045 DOI: 10.1016/0005-2736(84)90388-2  0.391
1984 Wertz PW, Downing DT, Freinkel RK, Traczyk TN. Sphingolipids of the Stratum Corneum and Lamellar Granules of Fetal Rat Epidemis Journal of Investigative Dermatology. 83: 193-195. PMID 6470524 DOI: 10.1111/1523-1747.Ep12263553  0.392
1983 Wertz PW, Colton SW, Downing DT. Comparison of the hydroxyacids from the epidermis and from the sebaceous glands of the horse. Comparative Biochemistry and Physiology B. 75: 217-220. PMID 6872514 DOI: 10.1016/0305-0491(83)90316-4  0.46
1983 Wertz PW, Cho ES, Downing DT. Effect of essential fatty acid deficiency on the epidermal sphingolipids of the rat. Biochimica Et Biophysica Acta. 753: 350-5. PMID 6615869 DOI: 10.1016/0005-2760(83)90058-9  0.365
1982 Birkby CS, Wertz PW, Downing DT. The polar lipids from keratinized tissues of some vertebrates Comparative Biochemistry and Physiology B. 73: 239-242. PMID 7172624 DOI: 10.1016/0305-0491(82)90278-4  0.436
1982 Wertz PW, Downing DT. Glycolipids in mammalian epidermis: structure and function in the water barrier Science. 217: 1261-1262. PMID 7112128 DOI: 10.1126/Science.7112128  0.41
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