Chih-Chi A. Hu, Ph.D. - Publications

Affiliations: 
2006 New York University, New York, NY, United States 
Area:
Cell Biology, Biochemistry

31/72 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Lee AC, Pingali SR, Pinilla-Ibarz JA, Atchison ML, Koumenis C, Argon Y, Thomas-Tikhonenko A, De Trez C, Hu CA, Tang CA. Loss of AID exacerbates the malignant progression of CLL. Leukemia. PMID 36042317 DOI: 10.1038/s41375-022-01663-5  0.363
2021 Choi HJ, Tang CA, Tian L, Wu Y, Sofi MH, Ticer T, Schutt SD, Hu CA, Yu XZ. XBP-1s Promotes B Cell Pathogenicity in Chronic GVHD by Restraining the Activity of Regulated IRE-1α-Dependent Decay. Frontiers in Immunology. 12: 705484. PMID 34659198 DOI: 10.3389/fimmu.2021.705484  0.416
2021 van Anken E, Bakunts A, Hu CA, Janssens S, Sitia R. Molecular Evaluation of Endoplasmic Reticulum Homeostasis Meets Humoral Immunity. Trends in Cell Biology. PMID 33685797 DOI: 10.1016/j.tcb.2021.02.004  0.315
2021 Wu Y, Tang CA, Mealer C, Bastian D, Hanief Sofi M, Tian L, Schutt S, Choi HJ, Ticer T, Zhang M, Sui X, Huang L, Mellor AL, Hu CA, Yu XZ. STING negatively regulates allogeneic T-cell responses by constraining antigen-presenting cell function. Cellular & Molecular Immunology. PMID 33500563 DOI: 10.1038/s41423-020-00611-6  0.315
2020 Shao A, Xu Q, Spalek WT, Cain CF, Kang CW, Tang CA, Del Valle JR, Hu CA. Development of tumor-targeting IRE-1 inhibitors for B cell cancer therapy. Molecular Cancer Therapeutics. PMID 33051362 DOI: 10.1158/1535-7163.MCT-20-0127  0.328
2020 Tang CA, Lee AC, Chang S, Xu Q, Shao A, Lo Y, Spalek WT, Pinilla-Ibarz JA, Del Valle JR, Hu CA. STING regulates BCR signaling in normal and malignant B cells. Cellular & Molecular Immunology. PMID 32999453 DOI: 10.1038/s41423-020-00552-0  0.378
2020 Shrestha N, Liu T, Ji Y, Reinert R, Torres M, Li X, Zhang M, Tang CA, Hu CA, Liu C, Naji A, Liu M, Lin JD, Kersten S, Arvan P, et al. Sel1L-Hrd1 ER-associated degradation maintains β-cell identity via TGFβ signaling. The Journal of Clinical Investigation. PMID 32182217 DOI: 10.1172/Jci134874  0.353
2020 Wu Y, Tang CA, Mealer C, Bastian D, Sofi MH, Tian L, Schutt SD, Choi H, Ticer T, Zhang M, Huang L, Mellor AL, Hu CA, Yu X. Sting Negatively Regulates Allogeneic T-Cell Responses By Constraining Antigen-Presenting Cell Function Blood. 136: 37-38. DOI: 10.1182/BLOOD-2020-139860  0.363
2019 Liao Y, Tham DKL, Liang FX, Chang J, Wei Y, Reddy SP, Sall J, Ren SJ, Chicote JU, Arnold LL, Hu CA, Romih R, Andrade LR, Rindler MJ, Cohen SM, et al. Mitochondrial lipid droplet formation as a detoxification mechanism to sequester and degrade excessive urothelial membranes. Molecular Biology of the Cell. mbcE19050284. PMID 31577526 DOI: 10.1091/Mbc.E19-05-0284  0.458
2019 Tang CA, Valle JRD, Hu CA. Abstract 2661: Targeting endoplasmic reticulum-resident proteins for the treatment of B cell cancer Cancer Research. 79: 2661-2661. DOI: 10.1158/1538-7445.Am2019-2661  0.474
2018 Betts BC, Locke FL, Sagatys EM, Pidala J, Walton K, Menges M, Reff J, Saha A, Djeu JY, Kiluk JV, Lee MC, Kim J, Kang CW, Tang CA, Frieling J, ... ... Hu CA, et al. Inhibition of Human Dendritic Cell ER Stress Response Reduces T Cell Alloreactivity Yet Spares Donor Anti-tumor Immunity. Frontiers in Immunology. 9: 2887. PMID 30574153 DOI: 10.3389/Fimmu.2018.02887  0.442
2018 Bagashev A, Sotillo E, Tang CA, Black KL, Perazzelli J, Seeholzer SH, Argon Y, Barrett DM, Grupp SA, Hu CA, Thomas-Tikhonenko A. CD19 alterations emerging after CD19-directed immunotherapy cause retention of the misfolded protein in the endoplasmic reticulum. Molecular and Cellular Biology. PMID 30104252 DOI: 10.1128/Mcb.00383-18  0.311
2018 De Leo A, Chen HS, Hu CA, Lieberman PM. Correction: Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage. Plos Pathogens. 14: e1007027. PMID 29694443 DOI: 10.1371/Journal.Ppat.1007027  0.307
2018 Tang CA, Chang S, Hashimoto A, Chen YJ, Kang CW, Mato AR, Del Valle JR, Gabrilovich D, Hu CA. Secretory IgM exacerbates tumor progression by inducing accumulations of MDSCs in mice. Cancer Immunology Research. PMID 29650518 DOI: 10.1158/2326-6066.Cir-17-0582  0.398
2018 Tang CA, Chang S, Paton AW, Paton JC, Gabrilovich DI, Ploegh HL, Del Valle JR, Hu CA. Phosphorylation of IRE1 at S729 regulates RIDD in B cells and antibody production after immunization. The Journal of Cell Biology. PMID 29511123 DOI: 10.1083/Jcb.201709137  0.425
2018 Schutt SD, Wu Y, Tang CA, Bastian D, Nguyen H, Sofi MH, Zhang M, Liu C, Helke K, Wilson C, Schnapp LM, Del Valle JR, Hu CA, Yu XZ. Inhibition of the IRE-1α/XBP-1 pathway prevents chronic GVHD and preserves the GVL effect in mice. Blood Advances. 2: 414-427. PMID 29483082 DOI: 10.1182/Bloodadvances.2017009068  0.443
2018 Xie H, Tang CA, Song JH, Mancuso A, Valle JRD, Cao J, Xiang Y, Dang CV, Lan R, Sanchez DJ, Keith B, Hu CA, Simon MC. IRE1α RNase-dependent lipid homeostasis promotes survival in Myc-transformed cancers. The Journal of Clinical Investigation. PMID 29381485 DOI: 10.1172/Jci95864  0.381
2018 Tang C, Chang S, Hashimoto A, Chen Y, Kang CW, Mato A, Valle JD, Gabrilovich D, Hu CA. Abstract 4756: Secretory IgM exacerbates tumor progression by inducing accumulations of myeloid-derived suppressor cells in mice Cancer Research. 78: 4756-4756. DOI: 10.1158/1538-7445.Am2018-4756  0.408
2018 Betts BC, Locke FL, Sagatys EM, Pidala JA, Walton K, Menges M, Reff J, Djeu JY, Kiluk JV, Lee MC, Kang CW, List AF, Valle JRD, Hu CA, Anasetti C. Inhibition of Human Dendritic Cell ER Stress Reduces Gvhd Without Impairing Tregs, NK Cells, or Anti-Tumor Ctl Biology of Blood and Marrow Transplantation. 24. DOI: 10.1016/J.Bbmt.2017.12.133  0.413
2017 De Leo A, Chen HS, Hu CA, Lieberman PM. Deregulation of KSHV latency conformation by ER-stress and caspase-dependent RAD21-cleavage. Plos Pathogens. 13: e1006596. PMID 28854249 DOI: 10.1371/Journal.Ppat.1006596  0.43
2017 Tavernier SJ, Osorio F, Vandersarren L, Vetters J, Vanlangenakker N, Van Isterdael G, Vergote K, De Rycke R, Parthoens E, van de Laar L, Iwawaki T, Del Valle JR, Hu CA, Lambrecht BN, Janssens S. Regulated IRE1-dependent mRNA decay sets the threshold for dendritic cell survival. Nature Cell Biology. PMID 28459443 DOI: 10.1038/Ncb3518  0.408
2017 Tang C, Chang S, Paton A, Paton J, Gabrilovich D, Ploegh H, Valle JD, Hu CA. Abstract LB-336: Specific serine phosphorylation of IRE-1 controls enhanced splicing of XBP-1 and regulated IRE-1-dependent decay (RIDD) Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Lb-336  0.431
2016 Zhao C, Brown RS, Tang CA, Hu CA, Schlieker C. Site-specific Proteolysis Mobilizes TorsinA from the Membrane of the Endoplasmic Reticulum in Response to ER Stress and B cell Stimulation. The Journal of Biological Chemistry. PMID 26953341 DOI: 10.1074/Jbc.M115.709337  0.31
2016 Tang CA, Zundell JA, Ranatunga S, Lin C, Nefedova Y, Del Valle JR, Hu CA. Agonist-Mediated Activation of STING Induces Apoptosis in Malignant B Cells. Cancer Research. PMID 26951929 DOI: 10.1158/0008-5472.Can-15-1885  0.496
2016 Schutt SD, Tang CA, Wu Y, Bastian DA, Valle JD, Hu CA, Yu X. Prevention of Chronic Gvhd By Targeting Xbp-1 Genetically or Pharmacologically in Mice Blood. 128: 4541-4541. DOI: 10.1182/Blood.V128.22.4541.4541  0.424
2007 Hu CA, Donald SP, Yu J, Lin WW, Liu Z, Steel G, Obie C, Valle D, Phang JM. Overexpression of proline oxidase induces proline-dependent and mitochondria-mediated apoptosis. Molecular and Cellular Biochemistry. 295: 85-92. PMID 16874462 DOI: 10.1007/S11010-006-9276-6  0.305
2006 Liu Y, Borchert GL, Surazynski A, Hu CA, Phang JM. Proline oxidase activates both intrinsic and extrinsic pathways for apoptosis: The role of ROS/superoxides, NFAT and MEK/ERK signaling Oncogene. 25: 5640-5647. PMID 16619034 DOI: 10.1038/sj.onc.1209564  0.301
2005 Liu Y, Borchert GL, Donald SP, Surazynski A, Hu CA, Weydert CJ, Oberley LW, Phang JM. MnSOD inhibits proline oxidase-induced apoptosis in colorectal cancer cells. Carcinogenesis. 26: 1335-42. PMID 15817612 DOI: 10.1093/Carcin/Bgi083  0.331
2005 Tang CA, Hu CA, Wei C, Wang J. Synergism of Rana catesbeiana ribonuclease and IFN-γ triggers distinct death machineries in different human cancer cells Febs Letters. 579: 265-270. PMID 15620724 DOI: 10.1016/J.Febslet.2004.11.086  0.427
2001 Hu CA, Tang CA, Wang J. Caspase activation in response to cytotoxic Rana catesbeiana ribonuclease in MCF‐7 cells Febs Letters. 503: 65-68. PMID 11513856 DOI: 10.1016/S0014-5793(01)02691-6  0.424
2001 Hu CA, Lee Y, Tang CA, Cheng J, Wang J. Synergistic Cytotoxicity of Rana catesbeiana Ribonuclease and IFN-γ on Hepatoma Cells Biochemical and Biophysical Research Communications. 280: 1229-1236. PMID 11162659 DOI: 10.1006/Bbrc.2001.4272  0.42
Low-probability matches (unlikely to be authored by this person)
2021 Zundell JA, Fukumoto T, Lin J, Fatkhudinov N, Nacarelli T, Kossenkov AV, Liu Q, Cassel J, Hu CA, Wu S, Zhang R. Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in -Mutant Ovarian Cancers. Cancer Research. PMID 34548333 DOI: 10.1158/0008-5472.CAN-21-1545  0.298
2021 Tcyganov EN, Hanabuchi S, Hashimoto A, Campbell D, Kar G, Slidel TW, Cayatte C, Landry A, Pilataxi F, Hayes S, Dougherty B, Hicks KC, Mulgrew K, Tang CA, Hu CA, et al. Distinct mechanisms govern populations of myeloid-derived suppressor cells in chronic viral infection and cancer. The Journal of Clinical Investigation. PMID 34228641 DOI: 10.1172/JCI145971  0.273
2019 Shao A, Kang CW, Tang CA, Cain C, Xu Q, Phoumyvong CM, Del Valle JR, Hu CA. Structural tailoring of a novel fluorescent IRE-1 RNase inhibitor to precisely control its activity. Journal of Medicinal Chemistry. PMID 31083990 DOI: 10.1021/Acs.Jmedchem.9B00269  0.263
2020 Ricci D, Tutton S, Chomistek S, Marrocco I, Ying M, Blumental D, Eletto D, Vargas J, Boyle S, Fazelinia H, Paton J, Paton A, Tang A, Hu CA, Gidalevitz T, et al. The connector between the kinase and RNase domains of IRE1α differentially controls the activities of this stress sensor The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.03046  0.257
2009 Yang Z, Gagarin D, St Laurent G, Hammell N, Toma I, Hu CA, Iwasa A, McCaffrey TA. Cardiovascular inflammation and lesion cell apoptosis: a novel connection via the interferon-inducible immunoproteasome. Arteriosclerosis, Thrombosis, and Vascular Biology. 29: 1213-9. PMID 19443843 DOI: 10.1161/Atvbaha.109.189407  0.251
2021 Lin J, Liu H, Fukumoto T, Zundell J, Yan Q, Tang CA, Wu S, Zhou W, Guo D, Karakashev S, Hu CA, Sarma K, Kossenkov AV, Zhang R. Targeting the IRE1α/XBP1s pathway suppresses CARM1-expressing ovarian cancer. Nature Communications. 12: 5321. PMID 34493732 DOI: 10.1038/s41467-021-25684-3  0.247
2022 Shao A, Xu Q, Kang CW, Cain CF, Lee AC, Tang CA, Del Valle JR, Hu CA. IRE-1-Targeting Caged Prodrug with Endoplasmic Reticulum Stress-Inducing and XBP-1S-Inhibiting Activities for Cancer Therapy. Molecular Pharmaceutics. PMID 35253431 DOI: 10.1021/acs.molpharmaceut.1c00639  0.247
2009 Castro CE, Hu C, Ploegh H, Boyce M, Lang M. Membrane Mechanics of B Lymphocyte Activation Biophysical Journal. 96: 627a. DOI: 10.1016/J.Bpj.2008.12.3316  0.245
2023 Ji Y, Luo Y, Wu Y, Sun Y, Zhao L, Xue Z, Sun M, Wei X, He Z, Wu SA, Lin LL, Lu Y, Chang L, Chen F, Chen S, ... ... Hu CA, et al. SEL1L-HRD1 endoplasmic reticulum-associated degradation controls STING-mediated innate immunity by limiting the size of the activable STING pool. Nature Cell Biology. PMID 37142791 DOI: 10.1038/s41556-023-01138-4  0.218
2021 Yoshida S, Wei X, Zhang G, O'Connor CL, Torres M, Zhou Z, Lin L, Menon R, Xu X, Zheng W, Xiong Y, Otto EA, Tang CA, Hua R, Verma R, ... ... Hu CA, et al. Endoplasmic reticulum-associated degradation is required for nephrin maturation and kidney glomerular filtration function. The Journal of Clinical Investigation. PMID 33591954 DOI: 10.1172/JCI143988  0.19
2021 McCaul N, Porter CM, Becker A, Tang CA, Wijne C, Chatterjee B, Bousbaine D, Bilate A, Hu CA, Ploegh H, Truttmann MC. Deletion of mFICD AMPylase alters cytokine secretion and affects visual short-term learning in vivo. The Journal of Biological Chemistry. 100991. PMID 34419450 DOI: 10.1016/j.jbc.2021.100991  0.176
2020 Del Valle JR, Betts BC, Yu XZ, Janssens S, Lambrecht BN, Simon MC, Hu CA. Clarifying the translational potential of B-I09. Nature Chemical Biology. 16: 1152. PMID 33067597 DOI: 10.1038/s41589-020-00654-w  0.159
2005 Bender HU, Almashanu S, Steel G, Hu CA, Lin WW, Willis A, Pulver A, Valle D. Functional consequences of PRODH missense mutations American Journal of Human Genetics. 76: 409-420. PMID 15662599 DOI: 10.1086/428142  0.106
2006 Bai B, Xie JP, Yan JF, Wang HH, Hu CA. A high throughput screening approach to identify Isocitrate lyase inhibitors from traditional Chinese medicine sources Drug Development Research. 67: 818-823. DOI: 10.1002/ddr.20152  0.094
2010 Hu CA, Yang TJ, Yang SL. A quasi gradient-index antireflection coating for solar cell Optics Infobase Conference Papers 0.085
2022 Bagashev A, Sotillo E, Tang CA, Black KL, Perazzelli J, Seeholzer SH, Argon Y, Barrett DM, Grupp SA, Hu CA, Thomas-Tikhonenko A. Correction for Bagashev et al., "CD19 Alterations Emerging after CD19-Directed Immunotherapy Cause Retention of the Misfolded Protein in the Endoplasmic Reticulum". Molecular and Cellular Biology. e0032822. PMID 35976030 DOI: 10.1128/mcb.00328-22  0.076
2007 Hu CA, Wen P. Recognition and analysis of genopathy Journal of Clinical Rehabilitative Tissue Engineering Research. 11: 8587-8589.  0.072
2023 Burns EA, Sanchez CG, Mathur S, Guerrero C, Muhsen IN, Sarfraz H, Hu CA, Tang CA, Shah SS, Tremont IW, Teh B, Ganguly S, Pingali SRK. Long term outcomes in older patients with primary central nervous system lymphoma: an analysis of the Texas Cancer Registry. Annals of Hematology. PMID 36922432 DOI: 10.1007/s00277-023-05140-6  0.066
1999 Camacho JA, Obie C, Biery B, Goodman BK, Hu CA, Almashanu S, Steel G, Casey R, Lambert M, Mitchell GA, Valle D. Hyperornithinaemia-hyperammonaemia-homocitrullinuria syndrome is caused by mutations in a gene encoding a mitochondrial ornithine transporter. Nature Genetics. 22: 151-8. PMID 10369256 DOI: 10.1038/9658  0.064
1994 Kuo SW, Huang WS, Hu CA, Liao WK, Fung TC, Wu SY. Effect of thyroxine administration on serum thyrotropin receptor antibody and thyroglobulin levels in patients with Graves' hyperthyroidism during antithyroid drug therapy European Journal of Endocrinology. 131: 125-130. PMID 8075781  0.063
2005 Hu CA, Wen P. Neurobiological mechanism of antipsychotic drugs Chinese Journal of Clinical Rehabilitation. 9: 169-171.  0.061
1976 Brody JS, Kagan HM, Manalo AD, Hu CA, Franzblau C. Lung lysyl oxidase and elastin synthesis during compensatory lung growth Chest. 69: 271-272. PMID 2452 DOI: 10.1378/CHEST.69.2_SUPPLEMENT.271  0.06
2023 Burns EA, Wilson JJ, Mathur S, Kieser R, Gong Z, Hu CA, Tang CA, Petkova J, Yuen C, Mai H, Shah S, Rice L, Ganguly S, Pingali SR. Long-term outcomes in patients with Burkitt lymphoma older than 65 years: an analysis of the Texas Cancer Registry. Annals of Hematology. PMID 37422592 DOI: 10.1007/s00277-023-05328-w  0.059
2013 Hu CA, Wu CJ, Yang TJ, Yang SL. Analysis of optical properties in cylindrical dielectric photonic crystal Optics Communications. 291: 424-434. DOI: 10.1016/j.optcom.2012.11.042  0.054
1982 Chen JC, Hu CA. Geochemistry of dacites from Chinkuashih area, northeastern Taiwan Proceedings of the Geological Society of China (Taiwan). 25: 67-81.  0.052
1997 Ding PYA, Sheu WHH, Hu CA, Pei D. Efficacy and safety of fluvastatin in patients with non-insulin- dependent diabetes mellitus and hypercholesterolemia Acta Cardiologica Sinica. 13: 138-144.  0.049
2006 Liang T, Peng MX, Wang L, Wang CL, Hu CA, Gao XL. Discovery and thermodynamics of granulite in the Caixia mountain, Xinjiang, China Journal of Chengdu University of Technology (Science and Technology Edition). 33: 141-148.  0.048
2013 Hu CA, Liu JW, Wu CJ, Yang TJ, Yang SL. Effects of superconducting film on the defect mode in dielectric photonic crystal heterostructure Solid State Communications. 157: 54-57. DOI: 10.1016/j.ssc.2012.12.022  0.038
1993 Kuo SW, Hu CA, Pei D, Ni KB, Shian LR. Efficacy of thyroxine-suppressive therapy and its relation to serum thyroglobulin levels in solitary nontoxic thyroid nodules Journal of the Formosan Medical Association. 92: 55-60. PMID 8099828  0.037
2013 Hu CA, Yang SL, Yang TJ. Switchable tunneling mode for cylindrical photonic quantum well consisting of photonic crystals containing liquid crystal Crown Copyright © 2013 Published by Elsevier B.V. All rights reserved Optics Communications. 297: 141-146. DOI: 10.1016/j.optcom.2012.12.054  0.037
2006 Hsieh MT, Chang CC, Hu CA, Huang YT, Yang SL, Chen JF, Hwang SW, Chen CH. Admittance spectroscopy of the electric properties of 1,4-bis[N-(1- naphthyl)-N′-phenylamino]-4,4′ diamine doped with tungsten oxide Idw '06 - Proceedings of the 13th International Display Workshops. 2: 1315-1318.  0.037
2011 Wang HJ, Hu CA, Liu JS. Distributed mining of association rules based on privacy-preserved method Proceedings - 3rd International Symposium On Information Science and Engineering, Isise 2010. 494-497. DOI: 10.1109/ISISE.2010.125  0.034
1986 Hu CA. Anti-H-theorem in Markov processes Physical Review A. 34: 596-601. DOI: 10.1103/PhysRevA.34.596  0.032
2013 Hu CA, Wu CJ, Yang TJ, Yang SL. Analysis of effective plasma frequency in a superconducting photonic crystal Journal of the Optical Society of America B: Optical Physics. 30: 366-369. DOI: 10.1364/JOSAB.30.000366  0.027
2012 Peng B, Hu Ca, Zhao Rz, Zheng Yq. The investigation of fault diagnosis based on GA-HPSO-NN Journal of Computers (Finland). 7: 2511-2517. DOI: 10.4304/jcp.7.10.2511-2517  0.027
2011 Xia P, Hao JM, Wang T, Hu CA, Zhao BZ, Xia YS, Xu QS. Changing gantry ratation speed for improving imaging quality of multislice spiral CT coronary angiography Chinese Journal of Medical Imaging Technology. 27: 831-835.  0.026
2011 Hu CA, Chang KP, Yang SL, Shen LF, Wu JJ, Yang TJ. Variation in the absolute photonic band gap of rods ranging from square to octagonal in square lattices Japanese Journal of Applied Physics. 50. DOI: 10.1143/JJAP.50.072002  0.024
2009 Lan T, Kang N, Zheng H, Hu CA. Study on the aerodynamic noise of a fastback car with rear view mirrors in uniform motion and accelerated motion Hangkong Dongli Xuebao/Journal of Aerospace Power. 24: 116-121.  0.021
2010 Wang HJ, Hu CA. Mining maximal patterns based on improved FP-tree and array technique 3rd International Symposium On Intelligent Information Technology and Security Informatics, Iitsi 2010. 567-571. DOI: 10.1109/IITSI.2010.185  0.02
2006 Hu CA. Brain organic changes and pathogenesis of cognitive impairment in patients with schizophrenia Chinese Journal of Clinical Rehabilitation. 10: 153-156.  0.012
2013 Zhang JG, Hu CA, Zhao BJ, Tang SL. Analysis of urinary iodine monitoring results of school-age children of Yi County in Hebei Province in 1998-2011 Chinese Journal of Endemiology. 32: 296-299. DOI: 10.3760/cma.j.issn.2095-4255.2013.03.016  0.01
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