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Erik Serrao, Ph.D. - Publications

Affiliations: 
2013 Pharmacy/Pharmaceutical Sciences University of Southern California, Los Angeles, CA, United States 
Area:
Pharmacy
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28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Jiang C, Lian X, Gao C, Sun X, Einkauf KB, Chevalier JM, Chen SMY, Hua S, Rhee B, Chang K, Blackmer JE, Osborn M, Peluso MJ, Hoh R, Somsouk M, ... ... Serrao E, et al. Distinct viral reservoirs in individuals with spontaneous control of HIV-1. Nature. PMID 32848246 DOI: 10.1038/S41586-020-2651-8  0.509
2017 Lesbats P, Serrao E, Maskell DP, Pye VE, O'Reilly N, Lindemann D, Engelman AN, Cherepanov P. Structural basis for spumavirus GAG tethering to chromatin. Proceedings of the National Academy of Sciences of the United States of America. 114: 5509-5514. PMID 28490494 DOI: 10.1073/Pnas.1621159114  0.365
2017 Ballandras-Colas A, Maskell DP, Serrao E, Locke J, Swuec P, Jónsson SR, Kotecha A, Cook NJ, Pye VE, Taylor IA, Andrésdóttir V, Engelman AN, Costa A, Cherepanov P. A supramolecular assembly mediates lentiviral DNA integration. Science (New York, N.Y.). 355: 93-95. PMID 28059770 DOI: 10.1126/Science.Aah7002  0.496
2016 Patel D, Antwi J, Koneru PC, Serrao E, Forli S, Kessl JJ, Feng L, Deng N, Levy RM, Fuchs JR, Olson AJ, Engelman AN, Bauman JD, Kvaratskhelia M, Arnold E. A New Class of Allosteric HIV-1 Integrase Inhibitors Identified by Crystallographic Fragment Screening of the Catalytic Core Domain. The Journal of Biological Chemistry. 291: 23569-23577. PMID 27645997 DOI: 10.1074/Jbc.M116.753384  0.595
2016 Zurnic I, Hütter S, Rzeha U, Stanke N, Reh J, Müllers E, Hamann MV, Kern T, Gerresheim GK, Lindel F, Serrao E, Lesbats P, Engelman AN, Cherepanov P, Lindemann D. Interactions of Prototype Foamy Virus Capsids with Host Cell Polo-Like Kinases Are Important for Efficient Viral DNA Integration. Plos Pathogens. 12: e1005860. PMID 27579920 DOI: 10.1371/Journal.Ppat.1005860  0.394
2016 Zerbato JM, Serrao E, Lenzi G, Kim B, Ambrose Z, Watkins SC, Engelman AN, Sluis-Cremer N. Establishment and Reversal of HIV-1 Latency in Naive and Central Memory CD4+ T Cells In Vitro. Journal of Virology. 90: 8059-73. PMID 27356901 DOI: 10.1128/Jvi.00553-16  0.481
2016 Saito A, Henning MS, Serrao E, Dubose BN, Teng S, Huang J, Li X, Saito N, Roy SP, Siddiqui MA, Ahn J, Tsuji M, Hatziioannou T, Engelman AN, Yamashita M. Capsid-CPSF6 Interaction Is Dispensable for HIV-1 Replication in Primary Cells but Is Selected during Virus Passage In Vivo. Journal of Virology. 90: 6918-6935. PMID 27307565 DOI: 10.1128/Jvi.00019-16  0.513
2016 Saito A, Ferhadian D, Sowd GA, Serrao E, Shi J, Halambage UD, Teng S, Soto J, Siddiqui MA, Engelman AN, Aiken C, Yamashita M. Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74. Journal of Virology. 90: 5808-5823. PMID 27076642 DOI: 10.1128/Jvi.03116-15  0.48
2016 Serrao E, Cherepanov P, Engelman AN. Amplification, Next-generation Sequencing, and Genomic DNA Mapping of Retroviral Integration Sites. Journal of Visualized Experiments : Jove. PMID 27023428 DOI: 10.3791/53840  0.332
2016 Rasheedi S, Shun MC, Serrao E, Sowd GA, Qian J, Hao C, Dasgupta T, Engelman AN, Skowronski J. The Cleavage and Polyadenylation Specificity Factor 6 (CPSF6) Subunit of the Capsid-recruited Pre-messenger RNA Cleavage Factor I (CFIm) Complex Mediates HIV-1 Integration into Genes. The Journal of Biological Chemistry. 291: 11809-19. PMID 26994143 DOI: 10.1074/Jbc.M116.721647  0.539
2016 Feng L, Dharmarajan V, Serrao E, Hoyte A, Larue RC, Slaughter A, Sharma A, Plumb MR, Kessl JJ, Fuchs JR, Bushman FD, Engelman AN, Griffin PR, Kvaratskhelia M. The Competitive Interplay between Allosteric HIV-1 Integrase Inhibitor BI/D and LEDGF/p75 during the Early Stage of HIV-1 Replication Adversely Affects Inhibitor Potency. Acs Chemical Biology. 11: 1313-21. PMID 26910179 DOI: 10.1021/Acschembio.6B00167  0.578
2016 Sowd GA, Serrao E, Wang H, Wang W, Fadel HJ, Poeschla EM, Engelman AN. A critical role for alternative polyadenylation factor CPSF6 in targeting HIV-1 integration to transcriptionally active chromatin. Proceedings of the National Academy of Sciences of the United States of America. 113: E1054-63. PMID 26858452 DOI: 10.1073/Pnas.1524213113  0.505
2016 Serrao E, Engelman AN. Sites of retroviral DNA integration: From basic research to clinical applications. Critical Reviews in Biochemistry and Molecular Biology. 51: 26-42. PMID 26508664 DOI: 10.3109/10409238.2015.1102859  0.414
2015 Maskell DP, Renault L, Serrao E, Lesbats P, Matadeen R, Hare S, Lindemann D, Engelman AN, Costa A, Cherepanov P. Structural basis for retroviral integration into nucleosomes. Nature. 523: 366-9. PMID 26061770 DOI: 10.1038/Nature14495  0.324
2015 Serrao E, Ballandras-Colas A, Cherepanov P, Maertens GN, Engelman AN. Key determinants of target DNA recognition by retroviral intasomes. Retrovirology. 12: 39. PMID 25924943 DOI: 10.1186/S12977-015-0167-3  0.476
2014 Matreyek KA, Wang W, Serrao E, Singh PK, Levin HL, Engelman A. Host and viral determinants for MxB restriction of HIV-1 infection. Retrovirology. 11: 90. PMID 25348155 DOI: 10.1186/S12977-014-0090-Z  0.48
2014 Kvaratskhelia M, Sharma A, Larue RC, Serrao E, Engelman A. Molecular mechanisms of retroviral integration site selection. Nucleic Acids Research. 42: 10209-25. PMID 25147212 DOI: 10.1093/Nar/Gku769  0.494
2014 Li BW, Zhang FH, Serrao E, Chen H, Sanchez TW, Yang LM, Neamati N, Zheng YT, Wang H, Long YQ. Design and discovery of flavonoid-based HIV-1 integrase inhibitors targeting both the active site and the interaction with LEDGF/p75. Bioorganic & Medicinal Chemistry. 22: 3146-58. PMID 24794743 DOI: 10.1016/J.Bmc.2014.04.016  0.717
2014 Serrao E, Krishnan L, Shun MC, Li X, Cherepanov P, Engelman A, Maertens GN. Integrase residues that determine nucleotide preferences at sites of HIV-1 integration: implications for the mechanism of target DNA binding. Nucleic Acids Research. 42: 5164-76. PMID 24520116 DOI: 10.1093/Nar/Gku136  0.547
2014 Serrao E, Wang CH, Frederick T, Lee CL, Anthony P, Arribas-Layton D, Baker K, Millstein J, Kovacs A, Neamati N. Alteration of select gene expression patterns in individuals infected with HIV-1. Journal of Medical Virology. 86: 678-86. PMID 24482297 DOI: 10.1002/Jmv.23872  0.609
2013 Ballandras-Colas A, Naraharisetty H, Li X, Serrao E, Engelman A. Biochemical characterization of novel retroviral integrase proteins. Plos One. 8: e76638. PMID 24124581 DOI: 10.1371/Journal.Pone.0076638  0.346
2013 Serrao E, Xu ZL, Debnath B, Christ F, Debyser Z, Long YQ, Neamati N. Discovery of a novel 5-carbonyl-1H-imidazole-4-carboxamide class of inhibitors of the HIV-1 integrase-LEDGF/p75 interaction. Bioorganic & Medicinal Chemistry. 21: 5963-72. PMID 23985689 DOI: 10.1016/J.Bmc.2013.07.047  0.674
2013 Serrao E, Debnath B, Otake H, Kuang Y, Christ F, Debyser Z, Neamati N. Fragment-based discovery of 8-hydroxyquinoline inhibitors of the HIV-1 integrase-lens epithelium-derived growth factor/p75 (IN-LEDGF/p75) interaction. Journal of Medicinal Chemistry. 56: 2311-22. PMID 23445471 DOI: 10.1021/Jm301632E  0.599
2012 Serrao E, Thys W, Demeulemeester J, Al-Mawsawi LQ, Christ F, Debyser Z, Neamati N. A symmetric region of the HIV-1 integrase dimerization interface is essential for viral replication. Plos One. 7: e45177. PMID 23028829 DOI: 10.1371/Journal.Pone.0045177  0.692
2011 Serrao E, Gundla R, Deng J, Odde S, Neamati N. Computer-Aided Techniques in Design of HIV-1 Integrase Inhibitors Hiv-1 Integrase: Mechanism and Inhibitor Design. 389-413. DOI: 10.1002/9781118015377.ch26  0.432
2010 Ramkumar K, Serrao E, Odde S, Neamati N. HIV-1 integrase inhibitors: 2007-2008 update. Medicinal Research Reviews. 30: 890-954. PMID 20135632 DOI: 10.1002/Med.20194  0.63
2009 Serrao E, Odde S, Ramkumar K, Neamati N. Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors. Retrovirology. 6: 25. PMID 19265512 DOI: 10.1186/1742-4690-6-25  0.662
2009 Serrao E, Odde S, Ramkumar K, Neamati N. Erratum to: Raltegravir, elvitegravir, and metoogravir: the birth of "me-too" HIV-1 integrase inhibitors Retrovirology. 6: 33. DOI: 10.1186/1742-4690-6-33  0.626
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