Ya Ke - Publications

Affiliations: 
Biomedical Sciences The Chinese University of Hong Kong, Hong Kong, Hong Kong 

54 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Ma J, Qian C, Bao Y, Liu MY, Ma HM, Shen MQ, Li W, Wang JJ, Bao YX, Liu Y, Ke Y, Qian ZM. Apolipoprotein E deficiency induces a progressive increase in tissue iron contents with age in mice. Redox Biology. 40: 101865. PMID 33493903 DOI: 10.1016/j.redox.2021.101865  0.356
2020 Mu MD, Qian ZM, Yang SX, Rong KL, Yung WH, Ke Y. Therapeutic effect of a histone demethylase inhibitor in Parkinson's disease. Cell Death & Disease. 11: 927. PMID 33116116 DOI: 10.1038/s41419-020-03105-5  0.377
2020 Yang G, Qian C, Zhang C, Bao Y, Liu MY, Jiang F, Li W, Liu Y, Ke Y, Qian ZM. Hepcidin attenuates the iron-mediated secondary neuronal injury after intracerebral hemorrhage in rats. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 32932001 DOI: 10.1016/J.Trsl.2020.09.002  0.513
2020 Liang T, Qian ZM, Mu MD, Yung WH, Ke Y. Brain Hepcidin Suppresses Major Pathologies in Experimental Parkinsonism. Iscience. 23: 101284. PMID 32623334 DOI: 10.1016/J.Isci.2020.101284  0.421
2019 Zhao P, Qian C, Chen YJ, Sheng Y, Ke Y, Qian ZM. Cystathionine β-synthase (CBS) deficiency suppresses erythropoiesis by disrupting expression of heme biosynthetic enzymes and transporter. Cell Death & Disease. 10: 708. PMID 31551410 DOI: 10.1038/S41419-019-1951-0  0.434
2019 Qian ZM, Ke Y. Hepcidin and its therapeutic potential in neurodegenerative disorders. Medicinal Research Reviews. PMID 31471929 DOI: 10.1002/Med.21631  0.476
2019 Qian ZM, Ke Y. Brain iron transport. Biological Reviews of the Cambridge Philosophical Society. PMID 31190441 DOI: 10.1111/brv.12521  0.367
2018 Zhang MW, Zhao P, Yung WH, Sheng Y, Ke Y, Qian ZM. Tissue iron is negatively correlated with TERC or TERT mRNA expression: a heterochronic parabiosis study in mice. Aging. PMID 30555055 DOI: 10.18632/aging.101676  0.311
2018 Zhang MW, Yang G, Zhou YF, Qian C, Mu MD, Ke Y, Qian ZM. Regulating ferroportin-1 and transferrin receptor-1 expression: A novel function of hydrogen sulfide. Journal of Cellular Physiology. PMID 30370692 DOI: 10.1002/Jcp.27431  0.419
2017 Zhang FL, Hou HM, Yin ZN, Chang L, Li FM, Chen YJ, Ke Y, Qian ZM. Impairment of Hepcidin Upregulation by Lipopolysaccharide in the Interleukin-6 Knockout Mouse Brain. Frontiers in Molecular Neuroscience. 10: 367. PMID 29163042 DOI: 10.3389/Fnmol.2017.00367  0.307
2017 Zhou YF, Wu XM, Zhou G, Mu MD, Zhang FL, Li FM, Qian C, Du F, Yung WH, Qian ZM, Ke Y. Cystathionine β-synthase is required for body iron homeostasis. Hepatology (Baltimore, Md.). PMID 28859237 DOI: 10.1002/Hep.29499  0.453
2017 Zhou YF, Zhang C, Yang G, Qian ZM, Zhang MW, Ma J, Zhang FL, Ke Y. Hepcidin Protects Neuron from Hemin-Mediated Injury by Reducing Iron. Frontiers in Physiology. 8: 332. PMID 28588503 DOI: 10.3389/Fphys.2017.00332  0.499
2017 Wu XM, Qian C, Zhou YF, Yan YC, Luo QQ, Yung WH, Zhang FL, Jiang LR, Qian ZM, Ke Y. Bi-directionally protective communication between neurons and astrocytes under ischemia. Redox Biology. 13: 20-31. PMID 28551085 DOI: 10.1016/J.Redox.2017.05.010  0.338
2017 Lou QQ, Zhou YF, Chen MY, Liu L, Ma J, Zhang MW, Zhang FL, Ke Y, Qian ZM. Fasting Up-regulates Ferroportin 1 Expression via a Ghrelin/GHSR/MAPK Signaling Pathway. Journal of Cellular Physiology. PMID 28338217 DOI: 10.1002/Jcp.25931  0.441
2017 Yu SS, Jiang LR, Ling Y, Qian ZM, Zhou YF, Li J, Ke Y. Nifedipine Increases Iron Content in WKPT-0293 Cl.2 Cells via Up-Regulating Iron Influx Proteins. Frontiers in Pharmacology. 8: 60. PMID 28243203 DOI: 10.3389/Fphar.2017.00060  0.482
2016 Zhang YT, Li FM, Guo YZ, Jiang LR, Ma J, Ke Y, Qian ZM. (Z)-ligustilide increases ferroportin1 expression and ferritin content in ischemic SH-SY5Y cells. European Journal of Pharmacology. PMID 27789221 DOI: 10.1016/J.Ejphar.2016.10.029  0.497
2016 Luo QQ, Qian ZM, Zhou YF, Zhang MW, Wang D, Zhu L, Ke Y. Expression of Iron Regulatory Protein 1 Is Regulated not only by HIF-1 but also pCREB under Hypoxia. International Journal of Biological Sciences. 12: 1191-1202. PMID 27766034 DOI: 10.7150/Ijbs.16437  0.356
2016 Lu LN, Qian ZM, Wu KC, Yung WH, Ke Y. Expression of Iron Transporters and Pathological Hallmarks of Parkinson's and Alzheimer's Diseases in the Brain of Young, Adult, and Aged Rats. Molecular Neurobiology. PMID 27578012 DOI: 10.1007/S12035-016-0067-0  0.475
2016 Yang G, Hu R, Zhang C, Qian C, Luo QQ, Yung WH, Ke Y, Feng H, Qian ZM. A combination of serum iron, ferritin and transferrin predicts outcome in patients with intracerebral hemorrhage. Scientific Reports. 6: 21970. PMID 26898550 DOI: 10.1038/Srep21970  0.351
2016 Zhu ZJ, Wu KC, Yung WH, Qian ZM, Ke Y. Differential interaction between iron and mutant alpha-synuclein causes distinctive parkinsonian phenotypes in drosophila. Biochimica Et Biophysica Acta. PMID 26769358 DOI: 10.1016/J.Bbadis.2016.01.002  0.398
2015 Gong J, Du F, Qian ZM, Luo QQ, Sheng Y, Yung WH, Xu YX, Ke Y. Pre-treatment of rats with ad-hepcidin prevents iron-induced oxidative stress in the brain. Free Radical Biology & Medicine. PMID 26582371 DOI: 10.1016/J.Freeradbiomed.2015.11.016  0.474
2015 Wu XM, Liu Y, Qian ZM, Luo QQ, Ke Y. CX3CL1/CX3CR1 Axis Plays a Key Role in Ischemia-Induced Oligodendrocyte Injury via p38MAPK Signaling Pathway. Molecular Neurobiology. PMID 26189830 DOI: 10.1007/S12035-015-9339-3  0.316
2015 Liu Y, Wu XM, Luo QQ, Huang S, Yang QW, Wang FX, Ke Y, Qian ZM. CX3CL1/CX3CR1-mediated microglia activation plays a detrimental role in ischemic mice brain via p38MAPK/PKC pathway. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. PMID 25966946 DOI: 10.1038/Jcbfm.2015.97  0.332
2014 Du F, Qian ZM, Luo Q, Yung WH, Ke Y. Hepcidin Suppresses Brain Iron Accumulation by Downregulating Iron Transport Proteins in Iron-Overloaded Rats. Molecular Neurobiology. PMID 25115800 DOI: 10.1007/S12035-014-8847-X  0.494
2014 Qian ZM, He X, Liang T, Wu KC, Yan YC, Lu LN, Yang G, Luo QQ, Yung WH, Ke Y. Lipopolysaccharides upregulate hepcidin in neuron via microglia and the IL-6/STAT3 signaling pathway. Molecular Neurobiology. 50: 811-20. PMID 24659348 DOI: 10.1007/S12035-014-8671-3  0.368
2014 Zhu ZJ, Wu KC, Qian ZM, Yung WH, Ke Y. Drosophila models for studying iron-related neurodegenerative diseases. Sheng Li Xue Bao : [Acta Physiologica Sinica]. 66: 47-54. PMID 24553869  0.32
2014 Huang XT, Qian ZM, He X, Gong Q, Wu KC, Jiang LR, Lu LN, Zhu ZJ, Zhang HY, Yung WH, Ke Y. Reducing iron in the brain: a novel pharmacologic mechanism of huperzine A in the treatment of Alzheimer's disease. Neurobiology of Aging. 35: 1045-54. PMID 24332448 DOI: 10.1016/J.Neurobiolaging.2013.11.004  0.442
2012 Du F, Qian ZM, Gong Q, Zhu ZJ, Lu L, Ke Y. The iron regulatory hormone hepcidin inhibits expression of iron release as well as iron uptake proteins in J774 cells. The Journal of Nutritional Biochemistry. 23: 1694-700. PMID 22560353 DOI: 10.1016/j.jnutbio.2011.12.002  0.381
2012 Du F, Fan M, Gong Q, Zhu LL, Zhu ZJ, Lu L, Ke Y. Effects of hypoxic preconditioning on the expression of iron influx and efflux proteins in primary neuron culture. Neurochemistry International. 60: 335-43. PMID 22281055 DOI: 10.1016/J.Neuint.2012.01.008  0.508
2012 Yang L, Fan M, Du F, Gong Q, Bi ZG, Zhu ZJ, Zhu LL, Ke Y. Hypoxic preconditioning increases iron transport rate in astrocytes. Biochimica Et Biophysica Acta. 1822: 500-8. PMID 22198321 DOI: 10.1016/J.Bbadis.2011.12.004  0.496
2012 Zhao ST, Huang XT, Zhang C, Ke Y. Humanin protects cortical neurons from ischemia and reperfusion injury by the increased activity of superoxide dismutase. Neurochemical Research. 37: 153-60. PMID 21935731 DOI: 10.1007/S11064-011-0593-0  0.304
2011 Du F, Wu XM, Gong Q, He X, Ke Y. Hyperthermia conditioned astrocyte-cultured medium protects neurons from ischemic injury by the up-regulation of HIF-1 alpha and the increased anti-apoptotic ability. European Journal of Pharmacology. 666: 19-25. PMID 21620821 DOI: 10.1016/J.Ejphar.2011.05.018  0.336
2011 Du F, Qian C, Qian ZM, Wu XM, Xie H, Yung WH, Ke Y. Hepcidin directly inhibits transferrin receptor 1 expression in astrocytes via a cyclic AMP-protein kinase A pathway. Glia. 59: 936-45. PMID 21438013 DOI: 10.1002/Glia.21166  0.486
2011 Wu XM, Qian ZM, Zhu L, Du F, Yung WH, Gong Q, Ke Y. Neuroprotective effect of ligustilide against ischaemia-reperfusion injury via up-regulation of erythropoietin and down-regulation of RTP801. British Journal of Pharmacology. 164: 332-43. PMID 21410687 DOI: 10.1111/J.1476-5381.2011.01337.X  0.358
2010 Du F, Zhu L, Qian ZM, Wu XM, Yung WH, Ke Y. Hyperthermic preconditioning protects astrocytes from ischemia/reperfusion injury by up-regulation of HIF-1 alpha expression and binding activity. Biochimica Et Biophysica Acta. 1802: 1048-53. PMID 20599612 DOI: 10.1016/J.Bbadis.2010.06.013  0.316
2009 Wu X, Qian Z, Ke Y, Du F, Zhu L. Ginkgolide B preconditioning protects neurons against ischaemia-induced apoptosis. Journal of Cellular and Molecular Medicine. 13: 4474-83. PMID 19602048 DOI: 10.1111/J.1582-4934.2008.00551.X  0.346
2009 Du F, Qian ZM, Zhu L, Wu XM, Yung WH, Tsim TY, Ke Y. L-DOPA neurotoxicity is mediated by up-regulation of DMT1-IRE expression. Plos One. 4: e4593. PMID 19240805 DOI: 10.1371/Journal.Pone.0004593  0.404
2009 Yu P, Chang YZ, Miao W, Wang SM, Cui R, Qian ZM, Ke Y, Duan XL. Effects of intracerebroventricular injection of iron dextran on the iron concentration and divalent metal transporter 1 expression in the caudate putamen and substantia nigra of rats. Anatomical Record (Hoboken, N.J. : 2007). 292: 225-33. PMID 19051252 DOI: 10.1002/Ar.20807  0.488
2009 Ge XH, Wang Q, Qian ZM, Zhu L, Du F, Yung WH, Yang L, Ke Y. The iron regulatory hormone hepcidin reduces ferroportin 1 content and iron release in H9C2 cardiomyocytes. The Journal of Nutritional Biochemistry. 20: 860-5. PMID 19027283 DOI: 10.1016/J.Jnutbio.2008.07.014  0.453
2008 Wang Q, Du F, Qian ZM, Ge XH, Zhu L, Yung WH, Yang L, Ke Y. Lipopolysaccharide induces a significant increase in expression of iron regulatory hormone hepcidin in the cortex and substantia nigra in rat brain. Endocrinology. 149: 3920-5. PMID 18450970 DOI: 10.1210/En.2007-1626  0.449
2008 He W, Qian Zhong M, Zhu L, Christopher Q, Du F, Yung WH, Ke Y. Ginkgolides mimic the effects of hypoxic preconditioning to protect C6 cells against ischemic injury by up-regulation of hypoxia-inducible factor-1 alpha and erythropoietin. The International Journal of Biochemistry & Cell Biology. 40: 651-62. PMID 18054269 DOI: 10.1016/J.Biocel.2007.10.013  0.311
2007 Ke Y, Qian ZM. Brain iron metabolism: neurobiology and neurochemistry. Progress in Neurobiology. 83: 149-73. PMID 17870230 DOI: 10.1016/J.Pneurobio.2007.07.009  0.445
2007 Qian ZM, Chang YZ, Zhu L, Yang L, Du JR, Ho KP, Wang Q, Li LZ, Wang CY, Ge X, Jing NL, Li L, Ke Y. Development and iron-dependent expression of hephaestin in different brain regions of rats. Journal of Cellular Biochemistry. 102: 1225-33. PMID 17516501 DOI: 10.1002/Jcb.21352  0.487
2007 Qian ZM, Chang YZ, Leung G, Du JR, Zhu L, Wang Q, Niu L, Xu YJ, Yang L, Ho KP, Ke Y. Expression of ferroportin1, hephaestin and ceruloplasmin in rat heart. Biochimica Et Biophysica Acta. 1772: 527-32. PMID 17383861 DOI: 10.1016/J.Bbadis.2007.02.006  0.46
2007 Chang YZ, Qian ZM, Du JR, Zhu L, Xu Y, Li LZ, Wang CY, Wang Q, Ge XH, Ho KP, Niu L, Ke Y. Ceruloplasmin expression and its role in iron transport in C6 cells. Neurochemistry International. 50: 726-33. PMID 17316903 DOI: 10.1016/J.Neuint.2007.01.004  0.477
2006 Ke Y, Ho K, Du J, Zhu L, Xu Y, Wang Q, Wang CY, Li L, Ge X, Chang Y, Qian ZM. Role of soluble ceruloplasmin in iron uptake by midbrain and hippocampus neurons. Journal of Cellular Biochemistry. 98: 912-9. PMID 16475160 DOI: 10.1002/Jcb.20740  0.479
2006 Chang YZ, Ke Y, Du JR, Halpern GM, Ho KP, Zhu L, Gu XS, Xu YJ, Wang Q, Li LZ, Wang CY, Qian ZM. Increased divalent metal transporter 1 expression might be associated with the neurotoxicity of L-DOPA. Molecular Pharmacology. 69: 968-74. PMID 16317110 DOI: 10.1124/Mol.105.017756  0.384
2005 Wang J, Qian ZM, Jiang H, Xie J, Ke Y. Treatment with nerve growth factor decreases expression of divalent metal transporter 1 and transferrin receptor in PC12 cells. Neurochemistry International. 47: 514-7. PMID 16137791 DOI: 10.1016/J.Neuint.2005.02.008  0.407
2005 Chen Y, Chen Y, Qian ZM, Du J, Duan X, Chang Y, Wang Q, Wang C, Ma YM, Xu Y, Li L, Ke Y. Iron loading inhibits ferroportin1 expression in PC12 cells. Neurochemistry International. 47: 507-13. PMID 16095759 DOI: 10.1016/J.Neuint.2005.06.004  0.486
2005 Chang YZ, Qian ZM, Wang K, Zhu L, Yang XD, Du JR, Jiang L, Ho KP, Wang Q, Ke Y. Effects of development and iron status on ceruloplasmin expression in rat brain. Journal of Cellular Physiology. 204: 623-31. PMID 15744747 DOI: 10.1002/Jcp.20321  0.386
2005 Ke Y, Chang YZ, Duan XL, Du JR, Zhu L, Wang K, Yang XD, Ho KP, Qian ZM. Age-dependent and iron-independent expression of two mRNA isoforms of divalent metal transporter 1 in rat brain. Neurobiology of Aging. 26: 739-48. PMID 15708449 DOI: 10.1016/J.Neurobiolaging.2004.06.002  0.482
2003 Ke Y, Ming Qian Z. Iron misregulation in the brain: a primary cause of neurodegenerative disorders. The Lancet. Neurology. 2: 246-53. PMID 12849213 DOI: 10.1016/S1474-4422(03)00353-3  0.47
2003 Ke Y, Chen YY, Chang YZ, Duan XL, Ho KP, Jiang DH, Wang K, Qian ZM. Post-transcriptional expression of DMT1 in the heart of rat. Journal of Cellular Physiology. 196: 124-30. PMID 12767048 DOI: 10.1002/Jcp.10284  0.428
2002 Xie JX, Tsoi YK, Chang YZ, Ke Y, Qian ZM. Effects of ferroxidase activity and species on ceruloplasmin mediated iron uptake by BT325 cells. Brain Research. Molecular Brain Research. 99: 12-6. PMID 11869803 DOI: 10.1016/S0169-328X(01)00336-9  0.449
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