Fionnuala Doyle - Publications

Affiliations: 
Novartis, Basel, Basel-Stadt, France 

183 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Huyett L, Dassau E, Pinsker JE, Doyle FJ, Kerr D. Minority groups and the artificial pancreas: who is (not) in line? The Lancet. Diabetes & Endocrinology. PMID 27492758 DOI: 10.1016/S2213-8587(16)30144-9  0.01
2016 Maahs DM, Buckingham BA, Castle JR, Cinar A, Damiano ER, Dassau E, DeVries JH, Doyle FJ, Griffen SC, Haidar A, Heinemann L, Hovorka R, Jones TW, Kollman C, Kovatchev B, et al. Outcome Measures for Artificial Pancreas Clinical Trials: A Consensus Report. Diabetes Care. 39: 1175-9. PMID 27330126 DOI: 10.2337/Dc15-2716  0.01
2016 Pinsker JE, Lee JB, Dassau E, Seborg DE, Bradley PK, Gondhalekar R, Bevier WC, Huyett L, Zisser HC, Doyle FJ. Randomized Crossover Comparison of Personalized MPC and PID Control Algorithms for the Artificial Pancreas. Diabetes Care. PMID 27289127 DOI: 10.2337/Dc15-2344  0.24
2016 Anderson SM, Raghinaru D, Pinsker JE, Boscari F, Renard E, Buckingham BA, Nimri R, Doyle FJ, Brown SA, Keith-Hynes P, Breton MD, Chernavvsky D, Bevier WC, Bradley PK, Bruttomesso D, et al. Multinational Home Use of Closed-Loop Control Is Safe and Effective. Diabetes Care. PMID 27208316 DOI: 10.2337/Dc15-2468  0.01
2016 Abel JH, Meeker K, Granados-Fuentes D, St John PC, Wang TJ, Bales BB, Doyle FJ, Herzog ED, Petzold LR. Functional network inference of the suprachiasmatic nucleus. Proceedings of the National Academy of Sciences of the United States of America. PMID 27044085 DOI: 10.1073/Pnas.1521178113  0.24
2016 Colmegna PH, Sánchez-Peña RS, Gondhalekar R, Dassau E, Doyle FJ. Reducing Glucose Variability Due to Meals and Postprandial Exercise in T1DM Using Switched LPV Control: In Silico Studies. Journal of Diabetes Science and Technology. PMID 27022097 DOI: 10.1177/1932296816638857  0.01
2016 Huyett LM, Mittal R, Zisser HC, Luxon ES, Yee A, Dassau E, Doyle FJ, Burnett DR. Preliminary Evaluation of a Long-Term Intraperitoneal Glucose Sensor With Flushing Mechanism. Journal of Diabetes Science and Technology. PMID 26993253 DOI: 10.1177/1932296816640542  0.01
2016 Gonder-Frederick LA, Grabman JH, Kovatchev B, Brown SA, Patek S, Basu A, Pinsker JE, Kudva YC, Wakeman CA, Dassau E, Cobelli C, Zisser HC, Doyle FJ. Is Psychological Stress a Factor for Incorporation Into Future Closed-Loop Systems? Journal of Diabetes Science and Technology. PMID 26969142 DOI: 10.1177/1932296816635199  0.01
2016 Núñez F, Wang Y, Teel AR, Doyle FJ. Synchronization of pulse-coupled oscillators to a global pacemaker Systems and Control Letters. 88: 75-80. DOI: 10.1016/J.Sysconle.2015.11.007  0.24
2015 Dasanayake IS, Seborg DE, Pinsker JE, Doyle FJ, Dassau E. Empirical Dynamic Model Identification for Blood-Glucose Dynamics in Response to Physical Activity. Proceedings of the ... Ieee Conference On Decision & Control / Ieee Control Systems Society. Ieee Conference On Decision & Control. 2015: 3834-3839. PMID 26997750 DOI: 10.1109/CDC.2015.7402815  0.24
2015 Colberg SR, Bevier WC, Pinsker JE, Lee JB, Ehrlich B, Dassau E, Doyle FJ, Chen KY, Kerr D. Challenges Associated With Exercise Studies in Type 1 Diabetes. Journal of Diabetes Science and Technology. PMID 26719137 DOI: 10.1177/1932296815625084  0.04
2015 St John PC, Doyle FJ. Quantifying Stochastic Noise in Cultured Circadian Reporter Cells. Plos Computational Biology. 11: e1004451. PMID 26588000 DOI: 10.1371/Journal.Pcbi.1004451  0.24
2015 Huyett LM, Dassau E, Zisser HC, Doyle FJ. Design and Evaluation of a Robust PID Controller for a Fully Implantable Artificial Pancreas. Industrial & Engineering Chemistry Research. 54: 10311-10321. PMID 26538805 DOI: 10.1021/Acs.Iecr.5B01237  0.24
2015 Dassau E, Brown SA, Basu A, Pinsker JE, Kudva YC, Gondhalekar R, Patek S, Lv D, Schiavon M, Lee JB, Man CD, Hinshaw L, Castorino K, Mallad A, Dadlani V, ... ... Doyle FJ, et al. Adjustment of Open-Loop Settings to Improve Closed-Loop Results in Type 1 Diabetes: A Multicenter Randomized Trial. The Journal of Clinical Endocrinology and Metabolism. jc20152081. PMID 26204135 DOI: 10.1210/Jc.2015-2081  0.24
2015 Finan DA, Dassau E, Breton MD, Patek SD, McCann TW, Kovatchev BP, Doyle FJ, Levy BL, Venugopalan R. Sensitivity of the Predictive Hypoglycemia Minimizer System to the Algorithm Aggressiveness Factor. Journal of Diabetes Science and Technology. PMID 26134834 DOI: 10.1177/1932296815593292  0.01
2015 Dasanayake IS, Bevier WC, Castorino K, Pinsker JE, Seborg DE, Doyle FJ, Dassau E. Early Detection of Physical Activity for People With Type 1 Diabetes Mellitus. Journal of Diabetes Science and Technology. 9: 1236-45. PMID 26134831 DOI: 10.1177/1932296815592409  0.04
2015 Zisser H, Dassau E, Lee JJ, Harvey RA, Bevier W, Doyle FJ. Clinical results of an automated artificial pancreas using technosphere inhaled insulin to mimic first-phase insulin secretion. Journal of Diabetes Science and Technology. 9: 564-72. PMID 25901023 DOI: 10.1177/1932296815582061  0.24
2015 Thakur GS, Daigle BJ, Dean KR, Zhang Y, Rodriguez-Fernandez M, Hammamieh R, Yang R, Jett M, Palma J, Petzold LR, Doyle FJ. Systems biology approach to understanding post-traumatic stress disorder. Molecular Biosystems. 11: 980-93. PMID 25627823 DOI: 10.1039/C4Mb00404C  0.24
2015 Klett H, Rodriguez-Fernandez M, Dineen S, Leon LR, Timmer J, Doyle FJ. Modeling the inflammatory response in the hypothalamus ensuing heat stroke: iterative cycle of model calibration, identifiability analysis, experimental design and data collection. Mathematical Biosciences. 260: 35-46. PMID 25119202 DOI: 10.1016/J.Mbs.2014.07.011  0.24
2015 Núñez F, Wang Y, Doyle FJ. Synchronization of pulse-coupled oscillators on (strongly) connected graphs Ieee Transactions On Automatic Control. 60: 1710-1715. DOI: 10.1109/Tac.2014.2361196  0.24
2015 Wang Y, Hori Y, Hara S, Doyle FJ. Collective Oscillation Period of Inter-Coupled Biological Negative Cyclic Feedback Oscillators Ieee Transactions On Automatic Control. 60: 1392-1397. DOI: 10.1109/Tac.2014.2342072  0.24
2015 Huyett LM, Dassau E, Zisser HC, Doyle FJ. The impact of glucose sensing dynamics on the closed-loop artificial pancreas Proceedings of the American Control Conference. 2015: 5116-5121. DOI: 10.1109/ACC.2015.7172137  0.24
2015 Gondhalekar R, Dassau E, Doyle FJ. Velocity-weighting to prevent controller-induced hypoglycemia in MPC of an artificial pancreas to treat T1DM Proceedings of the American Control Conference. 2015: 1635-1640. DOI: 10.1109/ACC.2015.7170967  0.24
2015 El-Khatib FH, Russell SJ, Magyar KL, Sinha M, McKeon K, Nathan DM, Damiano ER. Autonomous and continuous adaptation of a bihormonal bionic pancreas in adults and adolescents with type 1 diabetes Diabetes Technology and Therapeutics. 17: S32-S33. DOI: 10.1089/dia.2015.1504  0.01
2015 Bok Lee J, Dassau E, Doyle FJ. A run-to-run approach to enhance continuous glucose monitor accuracy based on continuous wear Ifac Proceedings Volumes (Ifac-Papersonline). 48: 237-242. DOI: 10.1016/J.Ifacol.2015.10.145  0.24
2015 Núñez F, Wang Y, Doyle FJ. Global synchronization of pulse-coupled oscillators interacting on cycle graphs Automatica. 52: 202-209. DOI: 10.1016/J.Automatica.2014.10.111  0.24
2015 Doyle FJ, Parker RS, Pearson RK, Ogunnaike BA. Plant-friendly identification of second-order Volterra models European Control Conference, Ecc 1999 - Conference Proceedings. 1096-1101.  0.24
2015 Mahadevan R, Doyle FJ. Nonlinear nonsquare control of a continuous bioreactor using flat outputs European Control Conference, Ecc 1999 - Conference Proceedings. 3757-3762.  0.24
2014 St John PC, Taylor SR, Abel JH, Doyle FJ. Amplitude metrics for cellular circadian bioluminescence reporters. Biophysical Journal. 107: 2712-22. PMID 25468350 DOI: 10.1016/J.Bpj.2014.10.026  0.24
2014 Wang Y, Hori Y, Hara S, Doyle FJ. Intercellular delay regulates the collective period of repressively coupled gene regulatory oscillator networks. Ieee Transactions On Automatic Control. 59: 211-216. PMID 25346544 DOI: 10.1109/Tac.2013.2270072  0.24
2014 Aschbacher K, Rodriguez-Fernandez M, van Wietmarschen H, Tomiyama AJ, Jain S, Epel E, Doyle FJ, van der Greef J. The hypothalamic-pituitary-adrenal-leptin axis and metabolic health: a systems approach to resilience, robustness and control. Interface Focus. 4: 20140020. PMID 25285198 DOI: 10.1098/Rsfs.2014.0020  0.24
2014 Lee JJ, Dassau E, Zisser H, Doyle FJ. Design and in silico evaluation of an intraperitoneal-subcutaneous (IP-SC) artificial pancreas. Computers & Chemical Engineering. 70: 180-188. PMID 25267863 DOI: 10.1016/J.Compchemeng.2014.02.024  0.24
2014 Doyle FJ, Huyett LM, Lee JB, Zisser HC, Kerr D, Dassau E. Response to comment on Doyle et al. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care 2014;37:1191-1197. Diabetes Care. 37: e228. PMID 25249687 DOI: 10.2337/Dc14-1693  0.24
2014 Chase HP, Doyle FJ, Zisser H, Renard E, Nimri R, Cobelli C, Buckingham BA, Maahs DM, Anderson S, Magni L, Lum J, Calhoun P, Kollman C, Beck RW. Multicenter closed-loop/hybrid meal bolus insulin delivery with type 1 diabetes. Diabetes Technology & Therapeutics. 16: 623-32. PMID 25188375 DOI: 10.1089/Dia.2014.0050  0.24
2014 Srinivasan A, Lee JB, Dassau E, Doyle FJ. Novel insulin delivery profiles for mixed meals for sensor-augmented pump and closed-loop artificial pancreas therapy for type 1 diabetes mellitus. Journal of Diabetes Science and Technology. 8: 957-68. PMID 25049364 DOI: 10.1177/1932296814543660  0.24
2014 Colmegna P, Sánchez Peña RS, Gondhalekar R, Dassau E, Doyle FJ. Reducing risks in type 1 diabetes using H∞ Control Ieee Transactions On Biomedical Engineering. 61: 2939-2947. PMID 25020013 DOI: 10.1109/Tbme.2014.2336772  0.24
2014 Zisser H, Renard E, Kovatchev B, Cobelli C, Avogaro A, Nimri R, Magni L, Buckingham BA, Chase HP, Doyle FJ, Lum J, Calhoun P, Kollman C, Dassau E, Farret A, et al. Multicenter closed-loop insulin delivery study points to challenges for keeping blood glucose in a safe range by a control algorithm in adults and adolescents with type 1 diabetes from various sites. Diabetes Technology & Therapeutics. 16: 613-22. PMID 25003311 DOI: 10.1089/Dia.2014.0066  0.24
2014 Kovatchev BP, Renard E, Cobelli C, Zisser HC, Keith-Hynes P, Anderson SM, Brown SA, Chernavvsky DR, Breton MD, Mize LB, Farret A, Place J, Bruttomesso D, Del Favero S, Boscari F, ... ... Doyle FJ, et al. Safety of outpatient closed-loop control: first randomized crossover trials of a wearable artificial pancreas. Diabetes Care. 37: 1789-96. PMID 24929429 DOI: 10.2337/Dc13-2076  0.24
2014 Hussain S, Rodriguez-Fernandez M, Braun GB, Doyle FJ, Ruoslahti E. Quantity and accessibility for specific targeting of receptors in tumours. Scientific Reports. 4: 5232. PMID 24912981 DOI: 10.1038/Srep05232  0.24
2014 Harvey RA, Dassau E, Zisser H, Seborg DE, Doyle FJ. Design of the Glucose Rate Increase Detector: A Meal Detection Module for the Health Monitoring System. Journal of Diabetes Science and Technology. 8: 307-320. PMID 24876583 DOI: 10.1177/1932296814523881  0.24
2014 Finan DA, McCann TW, Mackowiak L, Dassau E, Patek SD, Kovatchev BP, Doyle FJ, Zisser H, Anhalt H, Venugopalan R. Closed-Loop Control Performance of the Hypoglycemia-Hyperglycemia Minimizer (HHM) System in a Feasibility Study. Journal of Diabetes Science and Technology. 8: 35-42. PMID 24876535 DOI: 10.1177/1932296813511730  0.24
2014 Finan DA, McCann TW, Rhein K, Dassau E, Breton MD, Patek SD, Anhalt H, Kovatchev BP, Doyle FJ, Anderson SM, Zisser H, Venugopalan R. Effect of algorithm aggressiveness on the performance of the Hypoglycemia-Hyperglycemia Minimizer (HHM) System. Journal of Diabetes Science and Technology. 8: 685-90. PMID 24876443 DOI: 10.1177/1932296814534589  0.24
2014 Bevier WC, Fuller SM, Fuller RP, Rubin RR, Dassau E, Doyle FJ, Jovanovi? L, Zisser HC. Artificial pancreas (AP) clinical trial participants' acceptance of future AP technology. Diabetes Technology & Therapeutics. 16: 590-5. PMID 24811147 DOI: 10.1089/Dia.2013.0365  0.24
2014 Doyle FJ, Huyett LM, Lee JB, Zisser HC, Dassau E. Closed-loop artificial pancreas systems: engineering the algorithms. Diabetes Care. 37: 1191-7. PMID 24757226 DOI: 10.2337/Dc13-2108  0.24
2014 Burnett DR, Huyett LM, Zisser HC, Doyle FJ, Mensh BD. Glucose sensing in the peritoneal space offers faster kinetics than sensing in the subcutaneous space. Diabetes. 63: 2498-505. PMID 24622798 DOI: 10.2337/Db13-1649  0.24
2014 Harvey RA, Dassau E, Bevier WC, Seborg DE, Jovanovi? L, Doyle FJ, Zisser HC. Clinical evaluation of an automated artificial pancreas using zone-model predictive control and health monitoring system. Diabetes Technology & Therapeutics. 16: 348-57. PMID 24471561 DOI: 10.1089/Dia.2013.0231  0.24
2014 St John PC, Hirota T, Kay SA, Doyle FJ. Spatiotemporal separation of PER and CRY posttranslational regulation in the mammalian circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 111: 2040-5. PMID 24449901 DOI: 10.1073/Pnas.1323618111  0.01
2014 Yao M, Gu C, Doyle FJ, Zhu H, Redmond RW, Kochevar IE. Why is rose bengal more phototoxic to fibroblasts in vitro than in vivo? Photochemistry and Photobiology. 90: 297-305. PMID 24266530 DOI: 10.1111/Php.12215  0.04
2014 Lee JJ, Gondhalekar R, Doyle FJ. Design of an artificial pancreas using zone model predictive control with a Moving Horizon State Estimator Proceedings of the Ieee Conference On Decision and Control. 2015: 6975-6980. DOI: 10.1109/CDC.2014.7040485  0.24
2014 Gondhalekar R, Dassau E, Doyle FJ. Moving-horizon-like state estimation via continuous glucose monitor feedback in MPC of an artificial pancreas for type 1 diabetes Proceedings of the Ieee Conference On Decision and Control. 2015: 310-315. DOI: 10.1109/CDC.2014.7039399  0.24
2014 Gondhalekar R, Dassau E, Doyle FJ. MPC design for rapid pump-attenuation and expedited hyperglycemia response to treat T1DM with an Artificial Pancreas Proceedings of the American Control Conference. 4224-4230. DOI: 10.1109/ACC.2014.6859247  0.24
2014 Wang Y, Núñez F, Doyle FJ. Mobility induced network evolution speeds up synchronization of wireless sensor networks Proceedings of the American Control Conference. 3553-3558. DOI: 10.1109/ACC.2014.6858641  0.24
2014 Zhao C, Dassau E, Zisser HC, Jovanovič L, Doyle FJ, Seborg DE. Online prediction of subcutaneous glucose concentration for type 1 diabetes using empirical models and frequency-band separation Aiche Journal. 60: 574-584. DOI: 10.1002/Aic.14288  0.24
2014 Gondhalekar R, Dassau E, Doyle FJ. State estimation with sensor recalibrations and asynchronous measurements for MPC of an artificial pancreas to treat T1DM Ifac Proceedings Volumes (Ifac-Papersonline). 19: 224-230.  0.24
2014 St. John PC, Doyle FJ. Development of amplitude response curves for single-cell and population-level circadian systems Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area At the 2014 Aiche Annual Meeting. 1: 388-391.  0.24
2014 Huyett LM, Seborg DE, Doyle FJ. Design of a digital controller for a fully implantable closed-loop artificial pancreas Food, Pharmaceutical and Bioengineering Division 2014 - Core Programming Area At the 2014 Aiche Annual Meeting. 1: 365-366.  0.24
2013 Gondhalekar R, Dassau E, Zisser HC, Doyle FJ. Periodic-zone model predictive control for diurnal closed-loop operation of an artificial pancreas. Journal of Diabetes Science and Technology. 7: 1446-60. PMID 24351171 DOI: 10.1177/193229681300700605  0.24
2013 Wang Y, Núñez F, Doyle FJ. Statistical analysis of the pulse-coupled synchronization strategy for wireless sensor networks. Ieee Transactions On Signal Processing : a Publication of the Ieee Signal Processing Society. 61. PMID 24324322 DOI: 10.1109/Tsp.2013.2275511  0.24
2013 Widmer LA, Stelling J, Doyle FJ. Note: Parameter-independent bounding of the stochastic Michaelis-Menten steady-state intrinsic noise variance. The Journal of Chemical Physics. 139: 166102. PMID 24182089 DOI: 10.1063/1.4827496  0.24
2013 An S, Harang R, Meeker K, Granados-Fuentes D, Tsai CA, Mazuski C, Kim J, Doyle FJ, Petzold LR, Herzog ED. A neuropeptide speeds circadian entrainment by reducing intercellular synchrony. Proceedings of the National Academy of Sciences of the United States of America. 110: E4355-61. PMID 24167276 DOI: 10.1073/Pnas.1307088110  0.24
2013 Rodriguez-Fernandez M, Grosman B, Yuraszeck TM, Helwig BG, Leon LR, Doyle FJ. Modeling the intra- and extracellular cytokine signaling pathway under heat stroke in the liver. Plos One. 8: e73393. PMID 24039931 DOI: 10.1371/Journal.Pone.0073393  0.24
2013 Yang R, Daigle BJ, Muhie SY, Hammamieh R, Jett M, Petzold L, Doyle FJ. Core modular blood and brain biomarkers in social defeat mouse model for post traumatic stress disorder. Bmc Systems Biology. 7: 80. PMID 23962043 DOI: 10.1186/1752-0509-7-80  0.24
2013 Toffanin C, Zisser H, Doyle FJ, Dassau E. Dynamic insulin on board: incorporation of circadian insulin sensitivity variation. Journal of Diabetes Science and Technology. 7: 928-40. PMID 23911174 DOI: 10.1177/193229681300700415  0.24
2013 St John PC, Doyle FJ. Estimating confidence intervals in predicted responses for oscillatory biological models. Bmc Systems Biology. 7: 71. PMID 23895261 DOI: 10.1186/1752-0509-7-71  0.24
2013 Kovatchev BP, Renard E, Cobelli C, Zisser HC, Keith-Hynes P, Anderson SM, Brown SA, Chernavvsky DR, Breton MD, Farret A, Pelletier MJ, Place J, Bruttomesso D, Del Favero S, Visentin R, ... ... Doyle FJ, et al. Feasibility of outpatient fully integrated closed-loop control: first studies of wearable artificial pancreas. Diabetes Care. 36: 1851-8. PMID 23801798 DOI: 10.2337/Dc12-1965  0.24
2013 Cherfan D, Verter EE, Melki S, Gisel TE, Doyle FJ, Scarcelli G, Yun SH, Redmond RW, Kochevar IE. Collagen cross-linking using rose bengal and green light to increase corneal stiffness. Investigative Ophthalmology & Visual Science. 54: 3426-33. PMID 23599326 DOI: 10.1167/Iovs.12-11509  0.04
2013 Lee JJ, Dassau E, Zisser H, Harvey RA, Jovanovi? L, Doyle FJ. In silico evaluation of an artificial pancreas combining exogenous ultrafast-acting technosphere insulin with zone model predictive control. Journal of Diabetes Science and Technology. 7: 215-26. PMID 23439180 DOI: 10.1177/193229681300700127  0.24
2013 Dassau E, Zisser H, Harvey RA, Percival MW, Grosman B, Bevier W, Atlas E, Miller S, Nimri R, Jovanovic L, Doyle FJ. Clinical evaluation of a personalized artificial pancreas. Diabetes Care. 36: 801-9. PMID 23193210 DOI: 10.2337/Dc12-0948  0.24
2013 Lee JJ, Dassau E, Zisser H, Tamborlane W, Weinzimer S, Doyle FJ. The impact of insulin pharmacokinetics and pharmacodynamics on the closed-loop artificial pancreas Proceedings of the Ieee Conference On Decision and Control. 127-132. DOI: 10.1109/CDC.2013.6759870  0.24
2013 Wang Y, Doyle FJ. The influence of global cues and local coupling on the rate of synchronization in the presence of time delays Automatica. 49: 1838-1845. DOI: 10.1016/J.Automatica.2013.02.051  0.24
2012 Wang Y, Núñez F, Doyle FJ. Increasing sync rate of pulse-coupled oscillators via phase response function design: theory and application to wireless networks. Ieee Transactions On Control Systems Technology : a Publication of the Ieee Control Systems Society. 21. PMID 24391404 DOI: 10.1109/Tcst.2012.2205254  0.24
2012 Wang Y, Doyle FJ. Exponential synchronization rate of Kuramoto oscillators in the presence of a pacemaker. Ieee Transactions On Automatic Control. 58. PMID 24381351 DOI: 10.1109/Tac.2012.2215772  0.24
2012 Wang Y, Doyle FJ. Optimal phase response functions for fast pulse-coupled synchronization in wireless sensor networks. Ieee Transactions On Signal Processing : a Publication of the Ieee Signal Processing Society. 60. PMID 24324321 DOI: 10.1109/Tsp.2012.2208109  0.24
2012 Wang Y, Núñez F, Doyle FJ. Energy-efficient pulse-coupled synchronization strategy design for wireless sensor networks through reduced idle listening. Ieee Transactions On Signal Processing : a Publication of the Ieee Signal Processing Society. 60. PMID 24307831 DOI: 10.1109/Tsp.2012.2205685  0.24
2012 Luni C, Marth JD, Doyle FJ. Computational modeling of glucose transport in pancreatic β-cells identifies metabolic thresholds and therapeutic targets in diabetes. Plos One. 7: e53130. PMID 23300881 DOI: 10.1371/Journal.Pone.0053130  0.24
2012 Harvey RA, Dassau E, Zisser H, Seborg DE, Jovanovi? L, Doyle FJ. Design of the health monitoring system for the artificial pancreas: low glucose prediction module. Journal of Diabetes Science and Technology. 6: 1345-54. PMID 23294779 DOI: 10.1177/193229681200600613  0.24
2012 Webb AB, Taylor SR, Thoroughman KA, Doyle FJ, Herzog ED. Weakly circadian cells improve resynchrony. Plos Computational Biology. 8: e1002787. PMID 23209395 DOI: 10.1371/Journal.Pcbi.1002787  0.24
2012 Sriram K, Rodriguez-Fernandez M, Doyle FJ. A detailed modular analysis of heat-shock protein dynamics under acute and chronic stress and its implication in anxiety disorders. Plos One. 7: e42958. PMID 22937003 DOI: 10.1371/Journal.Pone.0042958  0.24
2012 Cobelli C, Renard E, Kovatchev BP, Keith-Hynes P, Ben Brahim N, Place J, Del Favero S, Breton M, Farret A, Bruttomesso D, Dassau E, Zisser H, Doyle FJ, Patek SD, Avogaro A. Pilot studies of wearable outpatient artificial pancreas in type 1 diabetes. Diabetes Care. 35: e65-7. PMID 22923687 DOI: 10.2337/Dc12-0660  0.24
2012 Hirota T, Lee JW, St John PC, Sawa M, Iwaisako K, Noguchi T, Pongsawakul PY, Sonntag T, Welsh DK, Brenner DA, Doyle FJ, Schultz PG, Kay SA. Identification of small molecule activators of cryptochrome. Science (New York, N.Y.). 337: 1094-7. PMID 22798407 DOI: 10.1126/Science.1223710  0.04
2012 Zhao C, Dassau E, Jovanovi? L, Zisser HC, Doyle FJ, Seborg DE. Predicting subcutaneous glucose concentration using a latent-variable-based statistical method for type 1 diabetes mellitus. Journal of Diabetes Science and Technology. 6: 617-33. PMID 22768893 DOI: 10.1177/193229681200600317  0.24
2012 Harvey RA, Dassau E, Zisser HC, Bevier W, Seborg DE, Jovanovi? L, Doyle FJ. Clinically relevant hypoglycemia prediction metrics for event mitigation. Diabetes Technology & Therapeutics. 14: 719-27. PMID 22690875 DOI: 10.1089/Dia.2011.0198  0.24
2012 Breton M, Farret A, Bruttomesso D, Anderson S, Magni L, Patek S, Dalla Man C, Place J, Demartini S, Del Favero S, Toffanin C, Hughes-Karvetski C, Dassau E, Zisser H, Doyle FJ, et al. Fully integrated artificial pancreas in type 1 diabetes: modular closed-loop glucose control maintains near normoglycemia. Diabetes. 61: 2230-7. PMID 22688340 DOI: 10.2337/Db11-1445  0.24
2012 Magrofuoco E, Elvassore N, Doyle FJ. Theoretical analysis of insulin-dependent glucose uptake heterogeneity in 3D bioreactor cell culture. Biotechnology Progress. 28: 833-45. PMID 22488757 DOI: 10.1002/Btpr.1539  0.24
2012 Patek SD, Magni L, Dassau E, Karvetski C, Toffanin C, De Nicolao G, Del Favero S, Breton M, Man CD, Renard E, Zisser H, Doyle FJ, Cobelli C, Kovatchev BP. Modular closed-loop control of diabetes. Ieee Transactions On Bio-Medical Engineering. 59: 2986-99. PMID 22481809 DOI: 10.1109/Tbme.2012.2192930  0.24
2012 Sriram K, Rodriguez-Fernandez M, Doyle FJ. Modeling cortisol dynamics in the neuro-endocrine axis distinguishes normal, depression, and post-traumatic stress disorder (PTSD) in humans. Plos Computational Biology. 8: e1002379. PMID 22359492 DOI: 10.1371/Journal.Pcbi.1002379  0.24
2012 Yang R, Daigle BJ, Petzold LR, Doyle FJ. Core module biomarker identification with network exploration for breast cancer metastasis. Bmc Bioinformatics. 13: 12. PMID 22257533 DOI: 10.1186/1471-2105-13-12  0.24
2012 van Heusden K, Dassau E, Zisser HC, Seborg DE, Doyle FJ. Control-relevant models for glucose control using a priori patient characteristics. Ieee Transactions On Bio-Medical Engineering. 59: 1839-49. PMID 22127988 DOI: 10.1109/Tbme.2011.2176939  0.24
2012 Núñez F, Wang Y, Teel AR, Doyle FJ. Bio-inspired synchronization of non-identical pulse-coupled oscillators subject to a global cue and local interactions? Ifac Proceedings Volumes (Ifac-Papersonline). 115-120. DOI: 10.3182/20120606-3-NL-3011.00102  0.24
2012 Doyle FJ. Zone model predictive control of an artificial pancreas Proceedings of the World Congress On Intelligent Control and Automation (Wcica). 8-9. DOI: 10.1109/WCICA.2012.6357829  0.24
2012 Doyle FJ. Ethics in publishing Ieee Control Systems. 32: 24-25. DOI: 10.1109/Mcs.2012.2214125  0.01
2012 Wang Y, Hori Y, Hara S, Doyle FJ. The collective oscillation period of inter-coupled Goodwin oscillators Proceedings of the Ieee Conference On Decision and Control. 1627-1632. DOI: 10.1109/CDC.2012.6426590  0.24
2012 Rodriguez-Fernandez M, Banga JR, Doyle FJ. Novel global sensitivity analysis methodology accounting for the crucial role of the distribution of input parameters: Application to systems biology models International Journal of Robust and Nonlinear Control. 22: 1082-1102. DOI: 10.1002/Rnc.2797  0.24
2012 Nunez F, Wang Y, Doyle FJ. Bio-inspired hybrid control of pulse-coupled oscillators and application to synchronization of a wireless network Proceedings of the American Control Conference. 2818-2823.  0.24
2011 Meeker K, Harang R, Webb AB, Welsh DK, Doyle FJ, Bonnet G, Herzog ED, Petzold LR. Wavelet measurement suggests cause of period instability in mammalian circadian neurons. Journal of Biological Rhythms. 26: 353-62. PMID 21775294 DOI: 10.1177/0748730411409863  0.24
2011 Boch CA, Ananthasubramaniam B, Sweeney AM, Doyle FJ, Morse DE. Effects of light dynamics on coral spawning synchrony. The Biological Bulletin. 220: 161-73. PMID 21712225 DOI: 10.1086/Bblv220N3P161  0.24
2011 Grosman B, Shaik OS, Helwig BG, Leon LR, Doyle FJ. A physiological systems approach to modeling and resetting of mouse thermoregulation under heat stress. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 938-45. PMID 21700894 DOI: 10.1152/Japplphysiol.00519.2010  0.01
2011 Luni C, Doyle FJ, Elvassore N. Cell population modelling describes intrinsic heterogeneity: a case study for hematopoietic stem cells. Iet Systems Biology. 5: 164-73. PMID 21639590 DOI: 10.1049/Iet-Syb.2009.0059  0.24
2011 Wang Y, Doyle FJ. On influences of global and local cues on the rate of synchronization of oscillator networks. Automatica : the Journal of Ifac, the International Federation of Automatic Control. 47: 1236-1242. PMID 21607201 DOI: 10.1016/J.Automatica.2011.01.074  0.24
2011 Percival MW, Wang Y, Grosman B, Dassau E, Zisser H, Jovanovi? L, Doyle FJ. Development of a multi-parametric model predictive control algorithm for insulin delivery in type 1 diabetes mellitus using clinical parameters. Journal of Process Control. 21: 391-404. PMID 21516218 DOI: 10.1016/J.Jprocont.2010.10.003  0.01
2011 Mirsky HP, Taylor SR, Harvey RA, Stelling J, Doyle FJ. Distribution-based sensitivity metric for highly variable biochemical systems. Iet Systems Biology. 5: 50. PMID 21261402 DOI: 10.1049/Iet-Syb.2009.0064  0.24
2011 Mercangöz M, Doyle FJ. Stability and convergence analysis of a distributed MPC scheme based on communication and iterative calculation of control action Ifac Proceedings Volumes (Ifac-Papersonline). 18: 263-270. DOI: 10.3182/20110828-6-IT-1002.03572  0.24
2011 Zhao C, Dassau E, Harvey RA, Seborg DE, Doyle FJ. Predictive glucose monitoring for type 1 diabetes using latent variable-based multivariate statistical analysis Ifac Proceedings Volumes (Ifac-Papersonline). 18: 7102-7107. DOI: 10.3182/20110828-6-It-1002.02330  0.24
2011 Grosman B, Dassau E, Zisser H, Jovanovič L, Doyle FJ. Multi-zone-MPC: Clinical inspired control algorithm for the artificial pancreas Ifac Proceedings Volumes (Ifac-Papersonline). 18: 7120-7125. DOI: 10.3182/20110828-6-It-1002.02215  0.24
2010 Luni C, Shoemaker JE, Sanft KR, Petzold LR, Doyle FJ. Confidence from uncertainty--a multi-target drug screening method from robust control theory. Bmc Systems Biology. 4: 161. PMID 21106087 DOI: 10.1186/1752-0509-4-161  0.24
2010 Yuraszeck TM, Neveu P, Rodriguez-Fernandez M, Robinson A, Kosik KS, Doyle FJ. Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology. Plos Computational Biology. 6: e1000997. PMID 21085645 DOI: 10.1371/Journal.Pcbi.1000997  0.24
2010 Percival MW, Bevier WC, Wang Y, Dassau E, Zisser HC, Jovanovi? L, Doyle FJ. Modeling the effects of subcutaneous insulin administration and carbohydrate consumption on blood glucose. Journal of Diabetes Science and Technology. 4: 1214-28. PMID 20920443 DOI: 10.1177/193229681000400522  0.01
2010 Wang Y, Dassau E, Zisser H, Jovanovi? L, Doyle FJ. Automatic bolus and adaptive basal algorithm for the artificial pancreatic β-cell. Diabetes Technology & Therapeutics. 12: 879-87. PMID 20879966 DOI: 10.1089/Dia.2010.0029  0.24
2010 Grosman B, Dassau E, Zisser HC, Jovanovic L, Doyle FJ. Zone model predictive control: a strategy to minimize hyper- and hypoglycemic events. Journal of Diabetes Science and Technology. 4: 961-75. PMID 20663463 DOI: 10.1177/193229681000400428  0.01
2010 Mauseth R, Wang Y, Dassau E, Kircher R, Matheson D, Zisser H, Jovanovic L, Doyle FJ. Proposed clinical application for tuning fuzzy logic controller of artificial pancreas utilizing a personalization factor. Journal of Diabetes Science and Technology. 4: 913-22. PMID 20663457 DOI: 10.1177/193229681000400422  0.08
2010 Harvey RA, Wang Y, Grosman B, Percival MW, Bevier W, Finan DA, Zisser H, Seborg DE, Jovanovic L, Doyle FJ, Dassau E. Quest for the artificial pancreas: combining technology with treatment. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 29: 53-62. PMID 20659841 DOI: 10.1109/Memb.2009.935711  0.24
2010 Campos-Cornejo F, Campos-Delgado DU, Espinoza-Trejo D, Zisser H, Jovanovic L, Doyle FJ, Dassau E. An advisory protocol for rapid- and slow-acting insulin therapy based on a run-to-run methodology. Diabetes Technology & Therapeutics. 12: 555-65. PMID 20597831 DOI: 10.1089/Dia.2009.0173  0.01
2010 Shoemaker JE, Gayen K, Garcia-Reyero N, Perkins EJ, Villeneuve DL, Liu L, Doyle FJ. Fathead minnow steroidogenesis: in silico analyses reveals tradeoffs between nominal target efficacy and robustness to cross-talk. Bmc Systems Biology. 4: 89. PMID 20579396 DOI: 10.1186/1752-0509-4-89  0.04
2010 Dassau E, Cameron F, Lee H, Bequette BW, Zisser H, Jovanovic L, Chase HP, Wilson DM, Buckingham BA, Doyle FJ. Real-Time hypoglycemia prediction suite using continuous glucose monitoring: a safety net for the artificial pancreas. Diabetes Care. 33: 1249-54. PMID 20508231 DOI: 10.2337/Dc09-1487  0.01
2010 Taylor SR, Webb AB, Smith KS, Petzold LR, Doyle FJ. Velocity response curves support the role of continuous entrainment in circadian clocks. Journal of Biological Rhythms. 25: 138-49. PMID 20348465 DOI: 10.1177/0748730409360949  0.24
2010 Buckingham B, Chase HP, Dassau E, Cobry E, Clinton P, Gage V, Caswell K, Wilkinson J, Cameron F, Lee H, Bequette BW, Doyle FJ. Prevention of nocturnal hypoglycemia using predictive alarm algorithms and insulin pump suspension. Diabetes Care. 33: 1013-7. PMID 20200307 DOI: 10.2337/Dc09-2303  0.08
2010 Wang Y, Dassau E, Doyle FJ. Closed-loop control of artificial pancreatic Beta -cell in type 1 diabetes mellitus using model predictive iterative learning control. Ieee Transactions On Bio-Medical Engineering. 57: 211-9. PMID 19527957 DOI: 10.1109/Tbme.2009.2024409  0.24
2009 Finan DA, Doyle FJ, Palerm CC, Bevier WC, Zisser HC, Jovanovic L, Seborg DE. Experimental evaluation of a recursive model identification technique for type 1 diabetes. Journal of Diabetes Science and Technology. 3: 1192-202. PMID 20144436 DOI: 10.1177/193229680900300526  0.24
2009 Wang Y, Percival MW, Dassau E, Zisser HC, Jovanovic L, Doyle FJ. A novel adaptive basal therapy based on the value and rate of change of blood glucose. Journal of Diabetes Science and Technology. 3: 1099-108. PMID 20144423 DOI: 10.1177/193229680900300513  0.01
2009 Kovatchev B, Patek S, Dassau E, Doyle FJ, Magni L, De Nicolao G, Cobelli C. Control to range for diabetes: functionality and modular architecture. Journal of Diabetes Science and Technology. 3: 1058-65. PMID 20144419 DOI: 10.1177/193229680900300509  0.01
2009 Dassau E, Jovanovic L, Doyle FJ, Zisser HC. Enhanced 911/global position system wizard: a telemedicine application for the prevention of severe hypoglycemia--monitor, alert, and locate. Journal of Diabetes Science and Technology. 3: 1501-6. PMID 20144406 DOI: 10.1177/193229680900300632  0.01
2009 Patek SD, Bequette BW, Breton M, Buckingham BA, Dassau E, Doyle FJ, Lum J, Magni L, Zisser H. In silico preclinical trials: methodology and engineering guide to closed-loop control in type 1 diabetes mellitus. Journal of Diabetes Science and Technology. 3: 269-82. PMID 20144358 DOI: 10.1177/193229680900300207  0.01
2009 Ellingsen C, Dassau E, Zisser H, Grosman B, Percival MW, Jovanovic L, Doyle FJ. Safety constraints in an artificial pancreatic beta cell: an implementation of model predictive control with insulin on board. Journal of Diabetes Science and Technology. 3: 536-44. PMID 20144293 DOI: 10.1177/193229680900300319  0.01
2009 Zisser H, Palerm CC, Bevier WC, Doyle FJ, Jovanovic L. Clinical update on optimal prandial insulin dosing using a refined run-to-run control algorithm. Journal of Diabetes Science and Technology. 3: 487-91. PMID 20144286 DOI: 10.1177/193229680900300312  0.01
2009 Bondia J, Dassau E, Zisser H, Calm R, Vehí J, Jovanovi? L, Doyle FJ. Coordinated basal-bolus infusion for tighter postprandial glucose control in insulin pump therapy. Journal of Diabetes Science and Technology. 3: 89-97. PMID 20046653 DOI: 10.1177/193229680900300110  0.01
2009 Mirsky HP, Liu AC, Welsh DK, Kay SA, Doyle FJ. A model of the cell-autonomous mammalian circadian clock. Proceedings of the National Academy of Sciences of the United States of America. 106: 11107-12. PMID 19549830 DOI: 10.1073/Pnas.0904837106  0.24
2009 Muller EB, Kooijman SA, Edmunds PJ, Doyle FJ, Nisbet RM. Dynamic energy budgets in syntrophic symbiotic relationships between heterotrophic hosts and photoautotrophic symbionts. Journal of Theoretical Biology. 259: 44-57. PMID 19285512 DOI: 10.1016/J.Jtbi.2009.03.004  0.24
2009 Dua P, Doyle FJ, Pistikopoulos EN. Multi-objective blood glucose control for type 1 diabetes. Medical & Biological Engineering & Computing. 47: 343-52. PMID 19214613 DOI: 10.1007/S11517-009-0453-0  0.24
2009 Dassau E, Palerm CC, Zisser H, Buckingham BA, Jovanovic L, Doyle FJ. In silico evaluation platform for artificial pancreatic beta-cell development--a dynamic simulator for closed-loop control with hardware-in-the-loop. Diabetes Technology & Therapeutics. 11: 187-94. PMID 19191486 DOI: 10.1089/Dia.2008.0055  0.01
2008 Percival MW, Zisser H, Jovanovic L, Doyle FJ. Closed-loop control and advisory mode evaluation of an artificial pancreatic Beta cell: use of proportional-integral-derivative equivalent model-based controllers. Journal of Diabetes Science and Technology. 2: 636-44. PMID 19885240 DOI: 10.1177/193229680800200415  0.01
2008 Bevier WC, Zisser HC, Jovanovic L, Finan DA, Palerm CC, Seborg DE, Doyle FJ. Use of continuous glucose monitoring to estimate insulin requirements in patients with type 1 diabetes mellitus during a short course of prednisone. Journal of Diabetes Science and Technology. 2: 578-83. PMID 19885233 DOI: 10.1177/193229680800200408  0.24
2008 Taylor SR, Gunawan R, Petzold LR, Doyle FJ. Sensitivity Measures for Oscillating Systems: Application to Mammalian Circadian Gene Network. Ieee Transactions On Automatic Control. 53: 177-188. PMID 19593456 DOI: 10.1109/Tac.2007.911364  0.24
2008 Bagheri N, Lawson MJ, Stelling J, Doyle FJ. Modeling the Drosophila melanogaster circadian oscillator via phase optimization. Journal of Biological Rhythms. 23: 525-37. PMID 19060261 DOI: 10.1177/0748730408325041  0.24
2008 Zisser H, Robinson L, Bevier W, Dassau E, Ellingsen C, Doyle FJ, Jovanovic L. Bolus calculator: a review of four "smart" insulin pumps. Diabetes Technology & Therapeutics. 10: 441-4. PMID 19049372 DOI: 10.1089/Dia.2007.0284  0.01
2008 Bagheri N, Stelling J, Doyle FJ. Circadian phase resetting via single and multiple control targets. Plos Computational Biology. 4: e1000104. PMID 18795146 DOI: 10.1371/Journal.Pcbi.1000104  0.24
2008 Palerm CC, Zisser H, Jovanovi? L, Doyle FJ. A Run-to-Run Control Strategy to Adjust Basal Insulin Infusion Rates in Type 1 Diabetes. Journal of Process Control. 18: 258-265. PMID 18709180 DOI: 10.1016/J.Jprocont.2007.07.010  0.01
2008 Hildebrandt S, Raden D, Petzold L, Robinson AS, Doyle FJ. A top-down approach to mechanistic biological modeling: application to the single-chain antibody folding pathway. Biophysical Journal. 95: 3535-58. PMID 18641066 DOI: 10.1529/Biophysj.107.125039  0.24
2008 Shoemaker JE, Doyle FJ. Identifying fragilities in biochemical networks: robust performance analysis of Fas signaling-induced apoptosis. Biophysical Journal. 95: 2610-23. PMID 18539637 DOI: 10.1529/Biophysj.107.123398  0.24
2008 Taylor SR, Doyle FJ, Petzold LR. Oscillator model reduction preserving the phase response: application to the circadian clock. Biophysical Journal. 95: 1658-73. PMID 18487303 DOI: 10.1529/Biophysj.107.128678  0.24
2008 Bagheri N, Taylor SR, Meeker K, Petzold LR, Doyle FJ. Synchrony and entrainment properties of robust circadian oscillators. Journal of the Royal Society, Interface / the Royal Society. 5: S17-28. PMID 18426774 DOI: 10.1098/Rsif.2008.0045.Focus  0.24
2007 Gillis R, Palerm CC, Zisser H, Jovanovic L, Seborg DE, Doyle FJ. Glucose estimation and prediction through meal responses using ambulatory subject data for advisory mode model predictive control. Journal of Diabetes Science and Technology. 1: 825-33. PMID 19885154 DOI: 10.1177/193229680700100605  0.24
2007 Park MJ, Dahlquist FW, Doyle FJ. Simultaneous high gain and wide dynamic range in a model of bacterial chemotaxis. Iet Systems Biology. 1: 222-9. PMID 17708429 DOI: 10.1049/Iet-Syb:20070003  0.24
2007 Kronauer RE, Gunzelmann G, Van Dongen HP, Doyle FJ, Klerman EB. Uncovering physiologic mechanisms of circadian rhythms and sleep/wake regulation through mathematical modeling. Journal of Biological Rhythms. 22: 233-45. PMID 17517913 DOI: 10.1177/0748730407301237  0.24
2007 Liu AC, Welsh DK, Ko CH, Tran HG, Zhang EE, Priest AA, Buhr ED, Singer O, Meeker K, Verma IM, Doyle FJ, Takahashi JS, Kay SA. Intercellular coupling confers robustness against mutations in the SCN circadian clock network. Cell. 129: 605-16. PMID 17482552 DOI: 10.1016/J.Cell.2007.02.047  0.24
2007 Gunawan R, Doyle FJ. Phase sensitivity analysis of circadian rhythm entrainment. Journal of Biological Rhythms. 22: 180-94. PMID 17440219 DOI: 10.1177/0748730407299194  0.24
2007 To TL, Henson MA, Herzog ED, Doyle FJ. A molecular model for intercellular synchronization in the mammalian circadian clock. Biophysical Journal. 92: 3792-803. PMID 17369417 DOI: 10.1529/Biophysj.106.094086  0.24
2007 Bevier WC, Zisser H, Palerm CC, Finan DA, Seborg DE, Doyle FJ, Wollitzer AO, Jovanovic L. Calculating the insulin to carbohydrate ratio using the hyperinsulinaemic-euglycaemic clamp-a novel use for a proven technique. Diabetes/Metabolism Research and Reviews. 23: 472-8. PMID 17315240 DOI: 10.1002/Dmrr.727  0.24
2007 Palerm CC, Zisser H, Bevier WC, Jovanovic L, Doyle FJ. Prandial insulin dosing using run-to-run control: application of clinical data and medical expertise to define a suitable performance metric. Diabetes Care. 30: 1131-6. PMID 17303792 DOI: 10.2337/Dc06-2115  0.01
2007 Bagheri N, Stelling J, Doyle FJ. Quantitative performance metrics for robustness in circadian rhythms. Bioinformatics (Oxford, England). 23: 358-64. PMID 17158515 DOI: 10.1093/Bioinformatics/Btl627  0.24
2006 Zeilinger MN, Farré EM, Taylor SR, Kay SA, Doyle FJ. A novel computational model of the circadian clock in Arabidopsis that incorporates PRR7 and PRR9. Molecular Systems Biology. 2: 58. PMID 17102803 DOI: 10.1038/Msb4100101  0.24
2006 Doyle FJ, Stelling J. Systems interface biology. Journal of the Royal Society, Interface / the Royal Society. 3: 603-16. PMID 16971329 DOI: 10.1098/Rsif.2006.0143  0.24
2006 Dua P, Doyle FJ, Pistikopoulos EN. Model-based blood glucose control for Type 1 diabetes via parametric programming. Ieee Transactions On Bio-Medical Engineering. 53: 1478-91. PMID 16916082 DOI: 10.1109/Tbme.2006.878075  0.24
2006 Bhartiya S, Chaudhary N, Venkatesh KV, Doyle FJ. Multiple feedback loop design in the tryptophan regulatory network of Escherichia coli suggests a paradigm for robust regulation of processes in series. Journal of the Royal Society, Interface / the Royal Society. 3: 383-91. PMID 16849267 DOI: 10.1098/Rsif.2005.0103  0.01
2006 Gunawan R, Doyle FJ. Isochron-based phase response analysis of circadian rhythms. Biophysical Journal. 91: 2131-41. PMID 16815910 DOI: 10.1529/Biophysj.105.078006  0.24
2006 Owens C, Zisser H, Jovanovic L, Srinivasan B, Bonvin D, Doyle FJ. Run-to-run control of blood glucose concentrations for people with Type 1 diabetes mellitus. Ieee Transactions On Bio-Medical Engineering. 53: 996-1005. PMID 16761826 DOI: 10.1109/TBME.2006.872818  0.01
2005 Gadkar KG, Varner J, Doyle FJ. Model identification of signal transduction networks from data using a state regulator problem. Systems Biology. 2: 17-30. PMID 17091579 DOI: 10.1049/sb:20045029  0.24
2005 Raden D, Hildebrandt S, Xu P, Bell E, Doyle FJ, Robinson AS. Analysis of cellular response to protein overexpression. Systems Biology. 152: 285-9. PMID 16986272 DOI: 10.1049/ip-syb:20050048  0.04
2005 Xu P, Raden D, Doyle FJ, Robinson AS. Analysis of unfolded protein response during single-chain antibody expression in Saccaromyces cerevisiae reveals different roles for BiP and PDI in folding. Metabolic Engineering. 7: 269-79. PMID 15990348 DOI: 10.1016/J.Ymben.2005.04.002  0.08
2005 Gadkar KG, Gunawan R, Doyle FJ. Iterative approach to model identification of biological networks. Bmc Bioinformatics. 6: 155. PMID 15967022 DOI: 10.1186/1471-2105-6-155  0.01
2005 Gunawan R, Cao Y, Petzold L, Doyle FJ. Sensitivity analysis of discrete stochastic systems. Biophysical Journal. 88: 2530-40. PMID 15695639 DOI: 10.1529/Biophysj.104.053405  0.24
2004 Stelling J, Sauer U, Szallasi Z, Doyle FJ, Doyle J. Robustness of cellular functions. Cell. 118: 675-85. PMID 15369668 DOI: 10.1016/J.Cell.2004.09.008  0.01
2004 Kremling A, Fischer S, Gadkar K, Doyle FJ, Sauter T, Bullinger E, Allgöwer F, Gilles ED. A benchmark for methods in reverse engineering and model discrimination: problem formulation and solutions. Genome Research. 14: 1773-85. PMID 15342560 DOI: 10.1101/Gr.1226004  0.01
2004 Stelling J, Gilles ED, Doyle FJ. Robustness properties of circadian clock architectures. Proceedings of the National Academy of Sciences of the United States of America. 101: 13210-5. PMID 15340155 DOI: 10.1073/Pnas.0401463101  0.24
2003 Zak DE, Pearson RK, Vadigepalli R, Gonye GE, Schwaber JS, Doyle FJ. Continuous-time identification of gene expression models. Omics : a Journal of Integrative Biology. 7: 373-86. PMID 14683610 DOI: 10.1089/153623103322637689  0.01
2003 Zak DE, Gonye GE, Schwaber JS, Doyle FJ. Importance of input perturbations and stochastic gene expression in the reverse engineering of genetic regulatory networks: insights from an identifiability analysis of an in silico network. Genome Research. 13: 2396-405. PMID 14597654 DOI: 10.1101/Gr.1198103  0.04
2003 Gadkar KG, Doyle FJ, Crowley TJ, Varner JD. Cybernetic model predictive control of a continuous bioreactor with cell recycle. Biotechnology Progress. 19: 1487-97. PMID 14524710 DOI: 10.1021/Bp025776D  0.01
2002 Kauffman KJ, Pridgen EM, Doyle FJ, Dhurjati PS, Robinson AS. Decreased protein expression and intermittent recoveries in BiP levels result from cellular stress during heterologous protein expression in Saccharomyces cerevisiae. Biotechnology Progress. 18: 942-50. PMID 12363344 DOI: 10.1021/Bp025518G  0.01
2002 Mahadevan R, Edwards JS, Doyle FJ. Dynamic flux balance analysis of diauxic growth in Escherichia coli. Biophysical Journal. 83: 1331-40. PMID 12202358 DOI: 10.1016/S0006-3495(02)73903-9  0.01
2001 Vadigepalli R, Doyle FJ, Schwaber JS. Analysis and neuronal modeling of the nonlinear characteristics of a local cardiac reflex in the rat. Neural Computation. 13: 2239-71. PMID 11570998 DOI: 10.1162/089976601750541796  0.24
2001 Parker RS, Doyle FJ. Control-relevant modeling in drug delivery. Advanced Drug Delivery Reviews. 48: 211-28. PMID 11369083 DOI: 10.1016/S0169-409X(01)00114-4  0.24
2001 Parker RS, Doyle FJ, Peppas NA. The intravenous route to blood glucose control. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 20: 65-73. PMID 11211662 DOI: 10.1109/51.897829  0.01
2001 Bequette BW, Doyle FJ. Automated control in biomedicine. Ieee Engineering in Medicine and Biology Magazine : the Quarterly Magazine of the Engineering in Medicine & Biology Society. 20: 22-3. PMID 11211658 DOI: 10.1109/MEMB.2001.897824  0.24
2000 Podual K, Doyle FJ, Peppas NA. Dynamic behavior of glucose oxidase-containing microparticles of poly(ethylene glycol)-grafted cationic hydrogels in an environment of changing pH. Biomaterials. 21: 1439-50. PMID 10872773 DOI: 10.1016/S0142-9612(00)00020-X  0.01
2000 Podual K, Doyle FJ, Peppas NA. Glucose-sensitivity of glucose oxidase-containing cationic copolymer hydrogels having poly(ethylene glycol) grafts. Journal of Controlled Release : Official Journal of the Controlled Release Society. 67: 9-17. PMID 10773324 DOI: 10.1016/S0168-3659(00)00195-4  0.01
1999 Cheng Z, Powley TL, Schwaber JS, Doyle FJ. Projections of the dorsal motor nucleus of the vagus to cardiac ganglia of rat atria: an anterograde tracing study. The Journal of Comparative Neurology. 410: 320-41. PMID 10414536 DOI: 10.1002/(Sici)1096-9861(19990726)410:2<320::Aid-Cne12>3.0.Co;2-5  0.24
1999 Parker RS, Doyle FJ, Peppas NA. A model-based algorithm for blood glucose control in type I diabetic patients. Ieee Transactions On Bio-Medical Engineering. 46: 148-57. PMID 9932336 DOI: 10.1109/10.740877  0.24
1997 Cheng Z, Powley TL, Schwaber JS, Doyle FJ. A laser confocal microscopic study of vagal afferent innervation of rat aortic arch: chemoreceptors as well as baroreceptors. Journal of the Autonomic Nervous System. 67: 1-14. PMID 9470139 DOI: 10.1016/S0165-1838(97)00085-4  0.24
1997 Kwatra HS, Doyle FJ, Rybak IA, Schwaber JS. A neuro-mimetic dynamic scheduling algorithm for control: analysis and applications. Neural Computation. 9: 479-502. PMID 9097469 DOI: 10.1162/Neco.1997.9.3.479  0.24
1997 Cheng Z, Powley TL, Schwaber JS, Doyle FJ. Vagal afferent innervation of the atria of the rat heart reconstructed with confocal microscopy. The Journal of Comparative Neurology. 381: 1-17. PMID 9087415 DOI: 10.1002/(Sici)1096-9861(19970428)381:1<1::Aid-Cne1>3.0.Co;2-5  0.24
1993 Nitsch RM, Blusztajn JK, Doyle FM, Robitaille Y, Wurtman RJ, Growdon JH, Kish SJ. Phospholipid metabolite levels are altered in cerebral cortex of patients with dominantly inherited olivopontocerebellar atrophy. Neuroscience Letters. 161: 191-4. PMID 8272265 DOI: 10.1016/0304-3940(93)90291-R  0.56
1984 Doyle FJ. Standards for dentistry. Journal (Canadian Dental Association). 50: 815-6. PMID 6391619  0.01
1978 Doyle FJ, Allon R. A window comparator to accommodate natural variability in psychophysiological measurements. Psychophysiology. 15: 496-8. PMID 693764  0.01
1967 Pos R, Rzadki EJ, McElroy JF, Doyle FJ. Research into the informational underload (sensory deprivation) hypothesis of mental illness: preliminary report. Canadian Psychiatric Association Journal. 12: 135-45. PMID 6068572  0.01
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