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Xiaohua Peng - Publications

Affiliations: 
Chemistry University of Wisconsin-Milwaukee, Milwaukee, WI 
Area:
Biochemistry
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39 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Zhang Q, Ali T, Lin Z, Peng X. Development of 4,4'-dibromobinaphthalene analogues with potent photo-inducible DNA cross-linking capability and cytotoxicity towards breast MDA-MB 468 cancer cells. Bioorganic Chemistry. 140: 106769. PMID 37633128 DOI: 10.1016/j.bioorg.2023.106769  0.559
2023 Cao S, Wang Y, Li DY, Peng X. H2O2-Inducible DNA Cross-linking Agents Capable of Releasing Multiple DNA Alkylators as Potent Anticancer Prodrugs. Chemmedchem. e202300273. PMID 37440359 DOI: 10.1002/cmdc.202300273  0.549
2022 Zhang Q, Lin Z, Peng X. Photo-Reactivity of Binaphthalene Triphenylphosphonium Salts: DNA Interstrand Cross-Link Formation and Substituent Effects. Chemical Research in Toxicology. PMID 35857929 DOI: 10.1021/acs.chemrestox.1c00401  0.58
2022 Zhou J, Liu Y, Wei Y, Zheng S, Gou S, Chen T, Yang Y, Lan T, Chen M, Liao Y, Zhang Q, Tang C, Liu Y, Wu Y, Peng X, et al. Eliminating predictable DNA off-target effects of cytosine base editor by using dual guiders including sgRNA and TALE. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 35443934 DOI: 10.1016/j.ymthe.2022.04.010  0.362
2021 Peng X, Fan H, Sun H, Zhang Q. Photoinduced DNA Interstrand Cross-linking by 1,1'-Biphenyl Analogues: Substituents and Leaving Groups Combine to Determine the Efficiency of Cross-Linker. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 33440025 DOI: 10.1002/chem.202005064  0.792
2020 Fan H, Peng X. Photoinduced DNA Interstrand Cross-Linking by Benzene Derivatives: Leaving Groups Determine the Efficiency of the Cross-Linker. The Journal of Organic Chemistry. PMID 33253574 DOI: 10.1021/acs.joc.0c02234  0.546
2019 Fan H, Sun H, Haque MM, Peng X. Effect of Triazole-Modified Thymidines on DNA and RNA Duplex Stability Acs Omega. 4: 5107-5116. DOI: 10.1021/ACSOMEGA.9B00089  0.745
2018 Chen W, Fan H, Balakrishnan K, Wang Y, Sun H, Fan Y, Gandhi V, Arnold LA, Peng X. Discovery and Optimization of Novel Hydrogen Peroxide Activated Aromatic Nitrogen Mustard Derivatives as Highly Potent Anticancer Agents. Journal of Medicinal Chemistry. PMID 30247905 DOI: 10.1021/Acs.Jmedchem.8B00559  0.71
2018 Lin Z, Fan H, Zhang Q, Peng X. Design, Synthesis, and Characterization of Binaphthalene Precursors as Photo-Activated DNA Interstrand Cross-Linkers. The Journal of Organic Chemistry. PMID 29929368 DOI: 10.1021/Acs.Joc.8B00642  0.624
2018 Peng X, Fan H, Sun H. Substituents Have a Large Effect on Photochemical Generation of Benzyl Cations and DNA Cross-Linking. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 29479750 DOI: 10.1002/Chem.201705929  0.796
2017 Wang Y, Lin Z, Fan H, Peng X. Corrigendum: Photoinduced DNA Interstrand Cross-Link Formation by Naphthalene Boronates via a Carbocation. Chemistry (Weinheim An Der Bergstrasse, Germany). 23: 11175. PMID 28815881 DOI: 10.1002/Chem.201703003  0.621
2017 Wang Y, Fan H, Balakrishnan K, Lin Z, Cao S, Chen W, Fan Y, Guthrie QA, Sun H, Teske KA, Gandhi V, Arnold LA, Peng X. Hydrogen peroxide activated quinone methide precursors with enhanced DNA cross-linking capability and cytotoxicity towards cancer cells. European Journal of Medicinal Chemistry. 133: 197-207. PMID 28388522 DOI: 10.1016/J.Ejmech.2017.03.041  0.774
2016 Sun H, Fan H, Eom H, Peng X. Coumarin-Induced DNA Ligation, Rearrangement to DNA Interstrand Cross-Links, and Photo-Release of Coumarin Moiety. Chembiochem : a European Journal of Chemical Biology. PMID 27558701 DOI: 10.1002/Cbic.201600240  0.796
2016 Wang Y, Liu S, Lin Z, Fan Y, Wang Y, Peng X. Photochemical Generation of Benzyl Cations That Selectively Cross-Link Guanine and Cytosine in DNA. Organic Letters. PMID 27191599 DOI: 10.1021/Acs.Orglett.6B00755  0.505
2016 Peng X, Wang Y, Lin Z, Fan H. Photo-Induced DNA Interstrand Cross-Link Formation by Naphthalene Boronates via a Carbocation. Chemistry (Weinheim An Der Bergstrasse, Germany). PMID 27189512 DOI: 10.1002/Chem.201601504  0.636
2016 Miao X, Li Z, Zhu A, Feng Z, Tian J, Peng X. Ultrasensitive electrochemical detection of protein tyrosine kinase-7 by gold nanoparticles and methylene blue assisted signal amplification. Biosensors & Bioelectronics. 83: 39-44. PMID 27101533 DOI: 10.1016/j.bios.2016.04.032  0.316
2015 Han Y, Chen W, Kuang Y, Sun H, Wang Z, Peng X. UV-Induced DNA Interstrand Cross-Linking and Direct Strand Breaks from a New Type of Binitroimidazole Analogue. Chemical Research in Toxicology. 28: 919-26. PMID 25844639 DOI: 10.1021/Tx500522R  0.807
2014 Sun H, Fan H, Peng X. Quantitative DNA interstrand cross-link formation by coumarin and thymine: structure determination, sequence effect, and fluorescence detection. The Journal of Organic Chemistry. 79: 11359-69. PMID 25372021 DOI: 10.1021/Jo5014756  0.794
2014 Haque MM, Sun H, Liu S, Wang Y, Peng X. Photoswitchable formation of a DNA interstrand cross-link by a coumarin-modified nucleotide. Angewandte Chemie (International Ed. in English). 53: 7001-5. PMID 24840115 DOI: 10.1002/Anie.201310609  0.766
2014 Chen W, Han Y, Peng X. Aromatic nitrogen mustard-based prodrugs: activity, selectivity, and the mechanism of DNA cross-linking. Chemistry (Weinheim An Der Bergstrasse, Germany). 20: 7410-8. PMID 24806710 DOI: 10.1002/Chem.201400090  0.585
2014 Chen W, Balakrishnan K, Kuang Y, Han Y, Fu M, Gandhi V, Peng X. Reactive oxygen species (ROS) inducible DNA cross-linking agents and their effect on cancer cells and normal lymphocytes. Journal of Medicinal Chemistry. 57: 4498-510. PMID 24801734 DOI: 10.1021/Jm401349G  0.46
2014 Cao S, Wang Y, Peng X. The leaving group strongly affects H₂O₂-induced DNA cross-linking by arylboronates. The Journal of Organic Chemistry. 79: 501-8. PMID 24378073 DOI: 10.1021/Jo401901X  0.615
2014 Haque MM, Peng X. DNA-associated click chemistry Science China Chemistry. 57: 215-231. DOI: 10.1007/S11426-013-5035-1  0.677
2013 Sun H, Peng X. Template-directed fluorogenic oligonucleotide ligation using "click" chemistry: detection of single nucleotide polymorphism in the human p53 tumor suppressor gene. Bioconjugate Chemistry. 24: 1226-34. PMID 23806001 DOI: 10.1021/Bc4001678  0.744
2013 Cao S, Christiansen R, Peng X. Substituent effects on oxidation-induced formation of quinone methides from arylboronic ester precursors. Chemistry (Weinheim An Der Bergstrasse, Germany). 19: 9050-8. PMID 23670793 DOI: 10.1002/Chem.201300539  0.378
2012 Kuang Y, Sun H, Blain JC, Peng X. Hypoxia-selective DNA interstrand cross-link formation by two modified nucleosides. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 12609-13. PMID 22936396 DOI: 10.1002/Chem.201201960  0.784
2012 Cao S, Wang Y, Peng X. ROS-inducible DNA cross-linking agent as a new anticancer prodrug building block. Chemistry (Weinheim An Der Bergstrasse, Germany). 18: 3850-4. PMID 22378607 DOI: 10.1002/Chem.201200075  0.545
2011 Kuang Y, Balakrishnan K, Gandhi V, Peng X. Hydrogen peroxide inducible DNA cross-linking agents: targeted anticancer prodrugs. Journal of the American Chemical Society. 133: 19278-81. PMID 22035519 DOI: 10.1021/Ja2073824  0.469
2010 Peng X, Li H, Seidman M. A Template-Mediated Click-Click Reaction: PNA-DNA, PNA-PNA (or Peptide) Ligation, and Single Nucleotide Discrimination. European Journal of Organic Chemistry. 2010: 4194-4197. PMID 23504541 DOI: 10.1002/ejoc.201000615  0.356
2010 Fülöp A, Peng X, Greenberg MM, Mokhir A. A nucleic acid-directed, red light-induced chemical reaction. Chemical Communications (Cambridge, England). 46: 5659-61. PMID 20574574 DOI: 10.1039/C0Cc00744G  0.471
2010 Peng X, Ghosh AK, Van Houten B, Greenberg MM. Nucleotide excision repair of a DNA interstrand cross-link produces single- and double-strand breaks. Biochemistry. 49: 11-9. PMID 20000382 DOI: 10.1021/Bi901603H  0.674
2008 Peng X, Pigli YZ, Rice PA, Greenberg MM. Protein binding has a large effect on radical mediated DNA damage. Journal of the American Chemical Society. 130: 12890-1. PMID 18778053 DOI: 10.1021/Ja805440V  0.638
2008 Bastia D, Zzaman S, Krings G, Saxena M, Peng X, Greenberg MM. Replication termination mechanism as revealed by Tus-mediated polar arrest of a sliding helicase. Proceedings of the National Academy of Sciences of the United States of America. 105: 12831-6. PMID 18708526 DOI: 10.1073/Pnas.0805898105  0.594
2008 Peng X, Hong IS, Li H, Seidman MM, Greenberg MM. Interstrand cross-link formation in duplex and triplex DNA by modified pyrimidines. Journal of the American Chemical Society. 130: 10299-306. PMID 18620398 DOI: 10.1021/Ja802177U  0.68
2008 Peng X, Greenberg MM. Facile SNP detection using bifunctional, cross-linking oligonucleotide probes. Nucleic Acids Research. 36: e31. PMID 18281702 DOI: 10.1093/Nar/Gkn052  0.565
2006 Li H, Peng X, Leonard P, Seela F. Binding of actinomycin C1 (D) and actinomin to base-modified oligonucleotide duplexes with parallel chain orientation. Bioorganic & Medicinal Chemistry. 14: 4089-100. PMID 16500105 DOI: 10.1016/j.bmc.2006.02.002  0.318
2006 Seela F, Peng X, Li H, Chittepu P, Shaikh KI, He J, He Y, Mikhailopulo I. Modified DNA: From Synthesis to Molecular Recognition Cheminform. 37. DOI: 10.1002/CHIN.200638264  0.417
2005 Seela F, Peng X, Li H. Base-pairing, tautomerism, and mismatch discrimination of 7-halogenated 7-deaza-2'-deoxyisoguanosine: oligonucleotide duplexes with parallel and antiparallel chain orientation. Journal of the American Chemical Society. 127: 7739-51. PMID 15913364 DOI: 10.1021/ja0425785  0.351
2004 Li H, Peng X, Seela F. Fluorescence quenching of parallel-stranded DNA bound ethidium bromide: the effect of 7-deaza-2'-deoxyisoguanosine and 7-halogenated derivatives. Bioorganic & Medicinal Chemistry Letters. 14: 6031-4. PMID 15546723 DOI: 10.1016/j.bmcl.2004.09.071  0.316
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