| Year |
Citation |
Score |
| 2009 |
Barron SC, McLaughlin JT, See JA, Richards VL, Rosenberg RL. An allosteric modulator of alpha7 nicotinic receptors, N-(5-Chloro-2,4-dimethoxyphenyl)-N'-(5-methyl-3-isoxazolyl)-urea (PNU-120596), causes conformational changes in the extracellular ligand binding domain similar to those caused by acetylcholine. Molecular Pharmacology. 76: 253-63. PMID 19411608 DOI: 10.1124/Mol.109.056226 |
0.618 |
|
| 2009 |
McLaughlin JT, Barron SC, See JA, Rosenberg RL. Conformational changes in alpha 7 acetylcholine receptors underlying allosteric modulation by divalent cations. Bmc Pharmacology. 9: 1. PMID 19144123 DOI: 10.1186/1471-2210-9-1 |
0.63 |
|
| 2009 |
Barron SC, Temple BR, See JA, Rosenberg RL, McLaughlin JT. Homology models of the alpha7 acetylcholine receptor based upon bacterial receptors: Comparison of experimental and in silico derived data Biochemical Pharmacology. 78: 907-908. DOI: 10.1016/J.Bcp.2009.06.050 |
0.593 |
|
| 2007 |
McLaughlin JT, Fu J, Rosenberg RL. Agonist-driven conformational changes in the inner beta-sheet of alpha7 nicotinic receptors. Molecular Pharmacology. 71: 1312-8. PMID 17325129 DOI: 10.1124/Mol.106.033092 |
0.625 |
|
| 2006 |
McLaughlin JT, Fu J, Sproul AD, Rosenberg RL. Role of the outer beta-sheet in divalent cation modulation of alpha7 nicotinic receptors. Molecular Pharmacology. 70: 16-22. PMID 16533908 DOI: 10.1124/Mol.106.023259 |
0.574 |
|
| 2003 |
Lyford LK, Sproul AD, Eddins D, McLaughlin JT, Rosenberg RL. Agonist-induced conformational changes in the extracellular domain of alpha 7 nicotinic acetylcholine receptors. Molecular Pharmacology. 64: 650-8. PMID 12920201 DOI: 10.1124/Mol.64.3.650 |
0.658 |
|
| 2002 |
Eddins D, Sproul AD, Lyford LK, McLaughlin JT, Rosenberg RL. Glutamate 172, essential for modulation of L247T alpha7 ACh receptors by Ca2+, lines the extracellular vestibule. American Journal of Physiology. Cell Physiology. 283: C1454-60. PMID 12372806 DOI: 10.1152/Ajpcell.00204.2002 |
0.626 |
|
| 1999 |
Levandoski MM, Lin Y, Moise L, McLaughlin JT, Cooper E, Hawrot E. Chimeric analysis of a neuronal nicotinic acetylcholine receptor reveals amino acids conferring sensitivity to alpha-bungarotoxin. The Journal of Biological Chemistry. 274: 26113-9. PMID 10473561 DOI: 10.1074/jbc.274.37.26113 |
0.39 |
|
| 1999 |
Spura A, Russin TS, Freedman ND, Grant M, McLaughlin JT, Hawrot E. Probing the agonist domain of the nicotinic acetylcholine receptor by cysteine scanning mutagenesis reveals residues in proximity to the alpha-bungarotoxin binding site. Biochemistry. 38: 4912-21. PMID 10213592 DOI: 10.1021/Bi982656Z |
0.454 |
|
| 1995 |
McLaughlin JT, Hawrot E, Yellen G. Covalent modification of engineered cysteines in the nicotinic acetylcholine receptor agonist-binding domain inhibits receptor activation. The Biochemical Journal. 310: 765-9. PMID 7575408 DOI: 10.1042/Bj3100765 |
0.49 |
|
| 1991 |
Tomaselli GF, McLaughlin JT, Jurman ME, Hawrot E, Yellen G. Mutations affecting agonist sensitivity of the nicotinic acetylcholine receptor. Biophysical Journal. 60: 721-7. PMID 1718469 DOI: 10.1016/S0006-3495(91)82102-6 |
0.369 |
|
| 1989 |
McLaughlin JT, Hawrot E. Structural characterization of alpha-bungarotoxin-binding proteins from Aplysia californica. Molecular Pharmacology. 35: 593-8. PMID 2542757 |
0.338 |
|
| 1985 |
Oswald RE, Pennow NN, McLaughlin JT. Demonstration and affinity labeling of a stereoselective binding site for a benzomorphan opiate on acetylcholine receptor-rich membranes from Torpedo electroplaque. Proceedings of the National Academy of Sciences of the United States of America. 82: 940-4. PMID 3856242 DOI: 10.1073/pnas.82.3.940 |
0.318 |
|
| 1984 |
Oswald RE, Bamberger MJ, McLaughlin JT. Mechanism of phencyclidine binding to the acetylcholine receptor from Torpedo electroplaque. Molecular Pharmacology. 25: 360-8. PMID 6727862 |
0.341 |
|
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