Ashley E. Walker, Ph.D. - Publications

Affiliations: 
2010 Integrative Physiology University of Colorado, Boulder, Boulder, CO, United States 
Area:
Physiology Biology, Recreation

45 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Reeve EH, Barnes JN, Moir ME, Walker AE. Impact of Arterial Stiffness on Cerebrovascular Function: A Review of Evidence from Humans and Preclincal Models. American Journal of Physiology. Heart and Circulatory Physiology. PMID 38214904 DOI: 10.1152/ajpheart.00592.2023  0.391
2023 Kehmeier MN, Khurana A, Bedell BR, Cullen AE, Cannon AT, Henson GD, Walker AE. The effects of dietary soy content on cerebral artery function and behavior in ovariectomized female mice. American Journal of Physiology. Heart and Circulatory Physiology. PMID 38156886 DOI: 10.1152/ajpheart.00618.2023  0.326
2023 Gogulamudi VR, Islam MT, Durrant JR, Adeyemo AO, Trott DW, Hyuhn MH, Zhu W, Donato AJ, Walker AE, Lesniewski LA. Heterozygosity for ADP-ribosylation factor 6 suppresses the burden and severity of atherosclerosis. Plos One. 18: e0285253. PMID 37163513 DOI: 10.1371/journal.pone.0285253  0.737
2023 Gogulamudi VR, Durrant JR, Adeyemo AO, Ho HM, Walker AE, Lesniewski LA. Advancing age increases the size and severity of spontaneous atheromas in mouse models of atherosclerosis. Geroscience. PMID 37086367 DOI: 10.1007/s11357-023-00776-8  0.649
2023 Winder NR, Reeve EH, Kronquist EK, Khurana A, Lee B, Nguyen T, Henson GD, Walker AE. High pulse pressure impairs cerebral artery endothelial function in young, but not old, mice. Experimental Gerontology. 112101. PMID 36690049 DOI: 10.1016/j.exger.2023.112101  0.317
2022 Kehmeier MN, Bedell BR, Cullen AE, Khurana A, D'Amico HJ, Henson GD, Walker AE. In vivo arterial stiffness, but not isolated artery endothelial function, varies with the mouse estrous cycle. American Journal of Physiology. Heart and Circulatory Physiology. PMID 36240435 DOI: 10.1152/ajpheart.00369.2022  0.345
2022 Reeve EH, Kronquist EK, Wolf JR, Lee B, Khurana A, Pham H, Cullen AE, Peterson JA, Meza A, Colton Bramwell R, Villasana L, Machin DR, Henson GD, Walker AE. Pyridoxamine treatment ameliorates large artery stiffening and cerebral artery endothelial dysfunction in old mice. Journal of Cerebral Blood Flow and Metabolism : Official Journal of the International Society of Cerebral Blood Flow and Metabolism. 271678X221130124. PMID 36189840 DOI: 10.1177/0271678X221130124  0.345
2021 Cole JA, Kehmeier MN, Bedell BR, Krishna Kumaran S, Henson GD, Walker AE. Sex Differences in the Relation Between Frailty and Endothelial Dysfunction in Old Mice. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. PMID 34664649 DOI: 10.1093/gerona/glab317  0.344
2020 Winder NR, Reeve EH, Walker AE. Large Artery Stiffness and Brain Health: Insights from Animal Models. American Journal of Physiology. Heart and Circulatory Physiology. PMID 33164578 DOI: 10.1152/ajpheart.00696.2020  0.324
2020 Tucker JR, Machin DR, Walker AE, Frech TM, Donato AJ. Autoantibody Subtype does not Impact Peripheral Endothelial Function and Hemodynamics in Systemic Sclerosis The Faseb Journal. 34: 1-1. DOI: 10.1096/Fasebj.2020.34.S1.06528  0.544
2019 Phuong TTT, Walker AE, Henson GD, Machin DR, Li DY, Donato AJ, Lesniewski LA. Deletion of Robo4 prevents high fat diet induced adipose artery and systemic metabolic dysfunction. Microcirculation (New York, N.Y. : 1994). e12540. PMID 30825241 DOI: 10.1111/Micc.12540  0.726
2019 Walker AE, Breevoort SR, Durrant JR, Liu Y, Machin DR, Dobson PS, Nielson EI, Meza AJ, Islam MT, Donato AJ, Lesniewski LA. The pro-atherogenic response to disturbed blood flow is increased by a western diet, but not by old age. Scientific Reports. 9: 2925. PMID 30814657 DOI: 10.1038/S41598-019-39466-X  0.759
2019 Walker AE, Kronquist EK, Chinen KT, Reihl KD, Li DY, Lesniewski LA, Donato AJ. Cerebral and skeletal muscle feed artery vasoconstrictor responses in a mouse model with greater large elastic artery stiffness. Experimental Physiology. PMID 30633428 DOI: 10.1113/Ep087453  0.727
2018 Garrett Morgan R, Walker AE, Trott DW, Machin DR, Henson GD, Reihl KD, Cawthon RM, Denchi EL, Liu Y, Bloom SI, Phuong TT, Richardson RS, Lesniewski LA, Donato AJ. Induced Trf2 deletion leads to aging vascular phenotype in mice associated with arterial telomere uncapping, senescence signaling, and oxidative stress. Journal of Molecular and Cellular Cardiology. PMID 30502348 DOI: 10.1016/J.Yjmcc.2018.11.014  0.783
2018 Morgan RG, Donato AJ, Walker AE. Telomere uncapping and vascular aging. American Journal of Physiology. Heart and Circulatory Physiology. PMID 29547021 DOI: 10.1152/Ajpheart.00008.2018  0.536
2016 Lesniewski LA, Seals DR, Walker AE, Henson GD, Blimline MW, Trott DW, Bosshardt GC, LaRocca TJ, Lawson BR, Zigler MC, Donato AJ. Dietary rapamycin supplementation reverses age-related vascular dysfunction and oxidative stress, while modulating nutrient-sensing, cell cycle, and senescence pathways. Aging Cell. PMID 27660040 DOI: 10.1111/Acel.12524  0.801
2015 Walker AE, Garrett Morgan R, Ives SJ, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ. Age-related arterial telomere uncapping and senescence is greater in women compared with men. Experimental Gerontology. PMID 26602606 DOI: 10.1016/J.Exger.2015.11.009  0.738
2015 Gibson CC, Davis CT, Zhu W, Bowman-Kirigin JA, Walker AE, Tai Z, Thomas KR, Donato AJ, Lesniewski LA, Li DY. Dietary Vitamin D and Its Metabolites Non-Genomically Stabilize the Endothelium. Plos One. 10: e0140370. PMID 26469335 DOI: 10.1371/Journal.Pone.0140370  0.688
2015 Jablonski KL, Donato AJ, Fleenor BS, Nowlan MJ, Walker AE, Kaplon RE, Ballak DB, Seals DR. Reduced large elastic artery stiffness with regular aerobic exercise in middle-aged and older adults: potential role of suppressed nuclear factor κ B signalling. Journal of Hypertension. PMID 26378681 DOI: 10.1097/Hjh.0000000000000742  0.775
2015 Donato AJ, Morgan RG, Walker AE, Lesniewski LA. Cellular and molecular biology of aging endothelial cells. Journal of Molecular and Cellular Cardiology. PMID 25655936 DOI: 10.1016/J.Yjmcc.2015.01.021  0.76
2015 Walker AE, Henson GD, Reihl KD, Morgan RG, Dobson PS, Nielson EI, Ling J, Mecham RP, Li DY, Lesniewski LA, Donato AJ. Greater impairments in cerebral artery compared with skeletal muscle feed artery endothelial function in a mouse model of increased large artery stiffness. The Journal of Physiology. 593: 1931-43. PMID 25627876 DOI: 10.1113/Jphysiol.2014.285338  0.768
2015 Frech T, Walker AE, Barrett-O'Keefe Z, Hopkins PN, Richardson RS, Wray DW, Donato AJ. Systemic sclerosis induces pronounced peripheral vascular dysfunction characterized by blunted peripheral vasoreactivity and endothelial dysfunction. Clinical Rheumatology. 34: 905-13. PMID 25511849 DOI: 10.1007/S10067-014-2834-5  0.654
2015 Gibson CC, Zhu W, Davis CT, Bowman-Kirigin JA, Chan AC, Ling J, Walker AE, Goitre L, Delle Monache S, Retta SF, Shiu YT, Grossmann AH, Thomas KR, Donato AJ, Lesniewski LA, et al. Strategy for identifying repurposed drugs for the treatment of cerebral cavernous malformation. Circulation. 131: 289-99. PMID 25486933 DOI: 10.1161/Circulationaha.114.010403  0.668
2014 Donato AJ, Henson GD, Hart CR, Layec G, Trinity JD, Bramwell RC, Enz RA, Morgan RG, Reihl KD, Hazra S, Walker AE, Richardson RS, Lesniewski LA. The impact of ageing on adipose structure, function and vasculature in the B6D2F1 mouse: evidence of significant multisystem dysfunction. The Journal of Physiology. 592: 4083-96. PMID 25038241 DOI: 10.1113/Jphysiol.2014.274175  0.758
2014 Walker AE, Kaplon RE, Pierce GL, Nowlan MJ, Seals DR. Prevention of age-related endothelial dysfunction by habitual aerobic exercise in healthy humans: possible role of nuclear factor κB. Clinical Science (London, England : 1979). 127: 645-54. PMID 24947434 DOI: 10.1042/Cs20140030  0.578
2014 Henson GD, Walker AE, Reihl KD, Donato AJ, Lesniewski LA. Dichotomous mechanisms of aortic stiffening in high-fat diet fed young and old B6D2F1 mice. Physiological Reports. 2: e00268. PMID 24760522 DOI: 10.1002/Phy2.268  0.739
2014 Morgan RG, Ives SJ, Walker AE, Cawthon RM, Andtbacka RH, Noyes D, Lesniewski LA, Richardson RS, Donato AJ. Role of arterial telomere dysfunction in hypertension: relative contributions of telomere shortening and telomere uncapping. Journal of Hypertension. 32: 1293-9. PMID 24686009 DOI: 10.1097/Hjh.0000000000000157  0.729
2014 Donato AJ, Lesniewski LA, Stuart D, Walker AE, Henson G, Sorensen L, Li D, Kohan DE. Smooth muscle specific disruption of the endothelin-A receptor in mice reduces arterial pressure, and vascular reactivity and affects vascular development. Life Sciences. 118: 238-43. PMID 24412386 DOI: 10.1016/J.Lfs.2013.12.209  0.719
2014 Walker AE, Henson GD, Reihl KD, Nielson EI, Morgan RG, Lesniewski LA, Donato AJ. Beneficial effects of lifelong caloric restriction on endothelial function are greater in conduit arteries compared to cerebral resistance arteries. Age (Dordrecht, Netherlands). 36: 559-69. PMID 24065292 DOI: 10.1007/S11357-013-9585-0  0.77
2013 Walker AE, Kaplon RE, Lucking SM, Russell-Nowlan MJ, Seals DR. Response to effect of fenofibrate on vascular endothelial function: statistical appraisal and its validity. Hypertension. 61: e56. PMID 23819148 DOI: 10.1161/Hypertensionaha.113.01310  0.536
2013 Donato AJ, Walker AE, Magerko KA, Bramwell RC, Black AD, Henson GD, Lawson BR, Lesniewski LA, Seals DR. Life-long caloric restriction reduces oxidative stress and preserves nitric oxide bioavailability and function in arteries of old mice. Aging Cell. 12: 772-83. PMID 23714110 DOI: 10.1111/Acel.12103  0.783
2013 DeVan AE, Eskurza I, Pierce GL, Walker AE, Jablonski KL, Kaplon RE, Seals DR. Regular aerobic exercise protects against impaired fasting plasma glucose-associated vascular endothelial dysfunction with aging. Clinical Science (London, England : 1979). 124: 325-31. PMID 23025811 DOI: 10.1042/Cs20120291  0.783
2012 Walker AE, Kaplon RE, Lucking SM, Russell-Nowlan MJ, Eckel RH, Seals DR. Fenofibrate improves vascular endothelial function by reducing oxidative stress while increasing endothelial nitric oxide synthase in healthy normolipidemic older adults. Hypertension. 60: 1517-23. PMID 23108655 DOI: 10.1161/Hypertensionaha.112.203661  0.602
2012 Donato AJ, Henson GD, Morgan RG, Enz RA, Walker AE, Lesniewski LA. TNF-α impairs endothelial function in adipose tissue resistance arteries of mice with diet-induced obesity. American Journal of Physiology. Heart and Circulatory Physiology. 303: H672-9. PMID 22821989 DOI: 10.1152/Ajpheart.00271.2012  0.752
2012 Christou DD, Pierce GL, Walker AE, Hwang MH, Yoo JK, Luttrell M, Meade TH, English M, Seals DR. Vascular smooth muscle responsiveness to nitric oxide is reduced in healthy adults with increased adiposity. American Journal of Physiology. Heart and Circulatory Physiology. 303: H743-50. PMID 22821988 DOI: 10.1152/Ajpheart.00394.2012  0.545
2012 Pierce GL, Jablonski KL, Walker AE, Seibert SM, DeVan AE, Black SM, Sharma S, Seals DR. Tetrahydrobiopterin supplementation enhances carotid artery compliance in healthy older men: a pilot study. American Journal of Hypertension. 25: 1050-4. PMID 22673017 DOI: 10.1038/Ajh.2012.70  0.795
2011 Kaplon RE, Walker AE, Seals DR. Plasma norepinephrine is an independent predictor of vascular endothelial function with aging in healthy women. Journal of Applied Physiology (Bethesda, Md. : 1985). 111: 1416-21. PMID 21903879 DOI: 10.1152/Japplphysiol.00721.2011  0.609
2011 Jablonski KL, Chonchol M, Pierce GL, Walker AE, Seals DR. 25-Hydroxyvitamin D deficiency is associated with inflammation-linked vascular endothelial dysfunction in middle-aged and older adults. Hypertension. 57: 63-9. PMID 21115878 DOI: 10.1161/Hypertensionaha.110.160929  0.766
2011 Pierce GL, Eskurza I, Walker AE, Fay TN, Seals DR. Sex-specific effects of habitual aerobic exercise on brachial artery flow-mediated dilation in middle-aged and older adults. Clinical Science (London, England : 1979). 120: 13-23. PMID 20642454 DOI: 10.1042/Cs20100174  0.555
2010 Walker AE, Seibert SM, Donato AJ, Pierce GL, Seals DR. Vascular endothelial function is related to white blood cell count and myeloperoxidase among healthy middle-aged and older adults. Hypertension. 55: 363-9. PMID 20048194 DOI: 10.1161/Hypertensionaha.109.145870  0.688
2009 Seals DR, Walker AE, Pierce GL, Lesniewski LA. Habitual exercise and vascular ageing. The Journal of Physiology. 587: 5541-9. PMID 19723776 DOI: 10.1113/Jphysiol.2009.178822  0.751
2009 Walker AE, Eskurza I, Pierce GL, Gates PE, Seals DR. Modulation of vascular endothelial function by low-density lipoprotein cholesterol with aging: influence of habitual exercise. American Journal of Hypertension. 22: 250-6. PMID 19114985 DOI: 10.1038/Ajh.2008.353  0.553
2008 Walker AE, Seibert SM, Seals DR. Peroxisome proliferator-activated receptor {alpha} activation improves endothelium-dependent dilation in healthy older men The Faseb Journal. 22: 64-64. DOI: 10.1096/Fasebj.22.2_Supplement.64  0.472
2007 Seals DR, Donato AJ, Pierce GL, Walker AE. Commentary on Viewpoint "Human experimentation: no accurate, quantitative data?". Journal of Applied Physiology (Bethesda, Md. : 1985). 102: 1294. PMID 17341743 DOI: 10.1152/japplphysiol.01301.2006  0.518
2007 Walker AE, Donato AJ, Eskurza I, Pierce GL, Silver AE, Seals DR. Plasma low‐density lipoprotein cholesterol modulates vascular endothelial function as well as systemic and vascular endothelial oxidative stress in middle‐aged and older men The Faseb Journal. 21. DOI: 10.1096/Fasebj.21.5.A445-A  0.766
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