Year |
Citation |
Score |
2013 |
Zhang Y, Chakraborty M, Cerda-Smith CG, Bratton RN, Maurer NE, Senser EM, Novak M. Chemistry of ring-substituted 4-(benzothiazol-2-yl)phenylnitrenium ions from antitumor 2-(4-aminophenyl)benzothiazoles. The Journal of Organic Chemistry. 78: 6992-7000. PMID 23786256 DOI: 10.1021/Jo400826F |
0.343 |
|
2012 |
Chakraborty M, Brzozowski CF, Novak M. Reversible formation of aryloxenium ions from the corresponding quinols under acidic conditions Journal of Physical Organic Chemistry. 25: 1236-1242. DOI: 10.1002/Poc.2999 |
0.399 |
|
2011 |
Rumpel A, Novak M, Walter J, Braunschweig B, Halik M, Peukert W. Tuning the molecular order of C60 functionalized phosphonic acid monolayers. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 15016-23. PMID 22044068 DOI: 10.1021/La203916H |
0.312 |
|
2011 |
Novak M, Chakraborty M. Reactions of a putative metabolite of the model antitumor drug 2-(4-aminophenyl)benzothiazole with purines and pyrimidines Journal of Physical Organic Chemistry. 24: 960-968. DOI: 10.1002/Poc.1905 |
0.418 |
|
2010 |
Chakraborty M, Jin KJ, Glover SA, Novak M. Characterization of the 4-(benzothiazol-2-yl)phenylnitrenium ion from a putative metabolite of a model antitumor drug. The Journal of Organic Chemistry. 75: 5296-304. PMID 20670034 DOI: 10.1021/Jo101275Y |
0.397 |
|
2010 |
Novak M, Chakraborty M. N‐Arylhydroxylamines and Chemical Carcinogenicity Patai's Chemistry of Functional Groups. DOI: 10.1002/9780470682531.Pat0507 |
0.381 |
|
2009 |
Chakraborty M, Jin KJ, Brewer SC, Peng HL, Platz MS, Novak M. Indirect and direct detection of the 4-(benzothiazol-2-yl)phenylnitrenium ion from a putative metabolite of a model anti-tumor drug. Organic Letters. 11: 4862-5. PMID 19788283 DOI: 10.1021/Ol901959Z |
0.35 |
|
2009 |
Wang YT, Novak M. Multiple decomposition pathways for the oxenium ion precursor O-(4-(4'-methylphenyl)phenyl)-N-methanesulfonylhydroxylamine. The Journal of Organic Chemistry. 74: 7697-706. PMID 19775151 DOI: 10.1021/Jo9014062 |
0.319 |
|
2009 |
Wang YT, Jin KJ, Myers LR, Glover SA, Novak M. Hydrolysis and photolysis of 4-Acetoxy-4-(benzothiazol-2-yl)-2,5-cyclohexadien-1-one, a model anti-tumor quinol ester. The Journal of Organic Chemistry. 74: 4463-71. PMID 19476314 DOI: 10.1021/Jo9008436 |
0.356 |
|
2008 |
Wang YT, Jin KJ, Leopold SH, Wang J, Peng HL, Platz MS, Xue J, Phillips DL, Glover SA, Novak M. Characterization of reactive intermediates generated during photolysis of 4-acetoxy-4-aryl-2,5-cyclohexadienones: oxenium ions and aryloxy radicals. Journal of the American Chemical Society. 130: 16021-30. PMID 18975865 DOI: 10.1021/Ja805336D |
0.361 |
|
2007 |
Novak M, Brinster AM, Dickhoff JN, Erb JM, Jones MP, Leopold SH, Vollman AT, Wang YT, Glover SA. Chemistry of 4-alkylaryloxenium ion "precursors": sound and fury signifying something? The Journal of Organic Chemistry. 72: 9954-62. PMID 18027966 DOI: 10.1021/Jo701853E |
0.455 |
|
2007 |
Wang YT, Wang J, Platz MS, Novak M. Direct detection of a transient oxenium ion in water generated by laser flash photolysis. Journal of the American Chemical Society. 129: 14566-7. PMID 17985908 DOI: 10.1021/Ja0764456 |
0.368 |
|
2007 |
Nguyen TM, Novak M. Synthesis and decomposition of an ester derivative of the procarcinogen and promutagen, PhIP, 2-amino-1-methyl-6-phenyl-1H-imidazo[4,5-b]pyridine: unusual nitrenium ion chemistry. The Journal of Organic Chemistry. 72: 4698-706. PMID 17542636 DOI: 10.1021/Jo070306P |
0.414 |
|
2006 |
Novak M, Poturalski MJ, Johnson WL, Jones MP, Wang Y, Glover SA. 4'-substituted-4-biphenylyloxenium ions: reactivity and selectivity in aqueous solution. The Journal of Organic Chemistry. 71: 3778-85. PMID 16674050 DOI: 10.1021/Jo060198R |
0.446 |
|
2005 |
Novak M, Glover SA. The hydrolysis of 4-acyloxy-4-substituted-2,5-cyclohexadienones: limitations of aryloxenium ion chemistry. Journal of the American Chemical Society. 127: 8090-7. PMID 15926835 DOI: 10.1021/Ja050899Q |
0.405 |
|
2005 |
Glover SA, Novak M. Computational studies of the properties of phenyloxenium ions A comparison with phenylnitrenium and phenylcarbenium ions Canadian Journal of Chemistry. 83: 1372-1381. DOI: 10.1139/V05-149 |
0.366 |
|
2004 |
Novak M, Glover SA. Generation and trapping of the 4-biphenylyloxenium ion by water and azide: comparisons with the 4-biphenylylnitrenium ion. Journal of the American Chemical Society. 126: 7748-9. PMID 15212501 DOI: 10.1021/Ja047488E |
0.35 |
|
2004 |
Novak M, Rajagopal S, Xu L, Kazerani S, Toth K, Brooks M, Nguyen T. Chemistry of carcinogenic and mutagenic metabolites of heterocyclic aromatic amines Journal of Physical Organic Chemistry. 17: 615-624. DOI: 10.1002/Poc.765 |
0.723 |
|
2003 |
Novak M, Nguyen TM. Unusual reactions of the model carcinogen N-acetoxy-N-acetyl-2-amino-alpha-carboline. The Journal of Organic Chemistry. 68: 9875-81. PMID 14682678 DOI: 10.1021/Jo034505U |
0.535 |
|
2003 |
Rajagopal S, Brooks ME, Nguyen TM, Novak M. Synthesis and characterization of the aqueous solution chemistry of the food-derived carcinogen model N-acetoxy-N-(1-methyl-5H-pyrido[4,5-b]indol-3-yl)acetamide and its N-pivaloyloxy analogue Tetrahedron. 59: 8003-8010. DOI: 10.1016/J.Tet.2003.08.005 |
0.526 |
|
2002 |
Novak M, Toth K, Rajagopal S, Brooks M, Hott LL, Moslener M. Reactivity and selectivity of the N-acetyl-Glu-P-1, N-acetyl-Glu-P-2, N-acetyl-MeIQx, and N-acetyl-IQx nitrenium ions: comparison to carbocyclic N-arylnitrenium ions. Journal of the American Chemical Society. 124: 7972-81. PMID 12095341 DOI: 10.1021/Ja0121944 |
0.754 |
|
2002 |
Novak M, Ruenz M, Kazerani S, Toth K, Nguyen TM, Heinrich B. Kinetics of hydrolysis of 8-(arylamino)-2'-deoxyguanosines. The Journal of Organic Chemistry. 67: 2303-8. PMID 11925245 DOI: 10.1021/Jo0163492 |
0.588 |
|
2001 |
Novak M, Rajagopal S. N-arylnitreniurn ions Advances in Physical Organic Chemistry. 36: 167-254. DOI: 10.1016/S0065-3160(01)36005-7 |
0.375 |
|
1999 |
Novak M, Lin J. Correlation Of Azide/Solvent Selectivities For Nitrenium Ions With Ab Initio Hydration Energies : Understanding The Kinetic Lability Of Nitrenium Ions In Aqueous Solution Journal of Organic Chemistry. 64: 6032-6040. DOI: 10.1021/Jo990581E |
0.392 |
|
1999 |
Novak M, VandeWater AJ, Brown AJ, Sanzenbacher SA, Hunt LA, Kolb BA, Brooks ME. Hydrolysis reactions of N-sulfonatooxy-N-acetyl-1-aminonaphthalene and N-sulfonatooxy-N-acetyl-2-aminonaphthalene: Limited correlation of nitrenium ion azide/solvent selectivities with mutagenicities of the corresponding amines Journal of Organic Chemistry. 64: 6023-6031. DOI: 10.1021/Jo990580M |
0.431 |
|
1998 |
Kazerani S, Novak M. Synthesis and Characterization of the Food-Derived Carcinogens 2-(Hydroxylamino)-alpha-carboline and 2-(Hydroxylamino)-3-methyl-alpha-carboline. The Journal of Organic Chemistry. 63: 895-897. PMID 11672091 DOI: 10.1021/Jo971786V |
0.599 |
|
1998 |
Novak M, Kayser KJ, Brooks ME. Azide and Solvent Trapping of Electrophilic Intermediates Generated during the Hydrolysis of N-(Sulfonatooxy)-N-acetyl-4-aminostilbene Journal of Organic Chemistry. 63: 5489-5496. DOI: 10.1021/Jo980500Z |
0.475 |
|
1998 |
Novak M, Xu L, Wolf RA. Nitrenium Ions from Food-Derived Heterocyclic Arylamine Mutagens Journal of the American Chemical Society. 120: 1643-1644. DOI: 10.1021/Ja974222H |
0.425 |
|
1998 |
Novak M, Kennedy SA. Inhibitory effect of DNA structure on the efficiency of reaction of guanosine moieties with a nitrenium ion Journal of Physical Organic Chemistry. 11: 71-76. DOI: 10.1002/(Sici)1099-1395(199801)11:1<71::Aid-Poc973>3.0.Co;2-H |
0.485 |
|
1997 |
Kennedy SA, Novak M, Kolb BA. Reactions of Ester Derivatives of CarcinogenicN-(4-Biphenylyl)hydroxylamine and the Corresponding Hydroxamic Acid with Purine Nucleosides Journal of the American Chemical Society. 119: 7654-7664. DOI: 10.1021/Ja970698P |
0.485 |
|
1996 |
Buccigross JM, Metz C, Elliot L, Becker P, Earley AS, Hayes JW, Novak M, Underwood GA. Synthesis and Kinetics of Hydrolysis of 3,5-Dimethyl-N-acetyl-p-benzoquinone Imine: An Undergraduate Laboratory Journal of Chemical Education. 73: 364. DOI: 10.1021/Ed073P364 |
0.308 |
|
1995 |
Novak M, Kahley MJ, Lin J, Kennedy SA, James TG. Involvement of Free Nitrenium Ions, Ion Pairs, and Preassociation Trapping in the Reactions of Ester Derivatives of N-Arylhydroxylamines and N-Arylhydroxamic Acids in Aqueous Solution The Journal of Organic Chemistry. 60: 8294-8304. DOI: 10.1021/Jo00130A034 |
0.489 |
|
1995 |
Novak M, Kennedy SA. Selective Trapping of N-Acetyl-N-(4-biphenylyl)nitrenium and N-Acetyl-N-(2-fluorenyl)nitrenium Ions by 2'-Deoxyguanosine in Aqueous Solution Journal of the American Chemical Society. 117: 574-575. DOI: 10.1021/Ja00106A083 |
0.464 |
|
1994 |
Novak M, Kahley MJ, Lin J, Kennedy SA, Swanegan LA. Reactivity Patterns of N-Arylnitrenium Ions: Lack of Correlation with .sigma.+ Journal of the American Chemical Society. 116: 11626-11627. DOI: 10.1021/Ja00104A076 |
0.437 |
|
1993 |
Novak M, Rangappa KS, Manitsas RK. Nucleophilic aromatic substitution on ester derivatives of carcinogenic N-arylhydroxamic acids by aniline and N,N-dimethylaniline Journal of Organic Chemistry. 58: 7813-7821. DOI: 10.1021/Jo00079A028 |
0.448 |
|
1993 |
Novak M, Helmick JS, Oberlies N, Rangappa KS, Clark WM, Swenton JS. The electrochemical preparation and kinetic and product studies of acylated quinol and quinol ether imines. In search of the hydrolysis products of the ultimate carcinogen of N-acetyl-2-aminofluorene The Journal of Organic Chemistry. 58: 867-878. DOI: 10.1021/Jo00056A019 |
0.42 |
|
1993 |
Novak M, Kahley MJ, Eiger E, Helmick JS, Peters HE. Reactivity and selectivity of nitrenium ions derived from ester derivatives of carcinogenic N-(4-biphenylyl)hydroxylamine and the corresponding hydroxamic acid Journal of the American Chemical Society. 115: 9453-9460. DOI: 10.1021/Ja00074A010 |
0.507 |
|
1992 |
Novak M, Rangappa KS. Nucleophilic substitution on the ultimate hepatacarcinogen N-(sulfonatooxy)-2-(acetylamino)fluorene by aromatic amines Journal of Organic Chemistry. 57: 1285-1290. DOI: 10.1021/Jo00030A043 |
0.419 |
|
1991 |
Helmick JS, Novak M. Nucleophilic substitution at nitrogen and carboxyl carbon of N-aryl-O-pivaloylhydroxylamines in aqueous solution: competition with SN1 solvolysis of model carcinogens The Journal of Organic Chemistry. 56: 2925-2927. DOI: 10.1021/Jo00008A064 |
0.332 |
|
1991 |
Novak M, Martin KA. Steric effects on the pKa of N-protonated N-acetyl-p-benzoquinone imines: evidence for hydration via N-protonation Journal of Organic Chemistry. 56: 1585-1590. DOI: 10.1021/Jo00004A045 |
0.359 |
|
1991 |
Helmick JS, Martin KA, Heinrich JL, Novak M. Mechanism of the reaction of carbon and nitrogen nucleophiles with the model carcinogens O-pivaloyl-N-arylhydroxylamines: competing SN2 substitution and SN1 solvolysis Journal of the American Chemical Society. 113: 3459-3466. DOI: 10.1021/Ja00009A035 |
0.4 |
|
1990 |
Novak M, Martin KA, Heinrich JL, Peet KM, Mohler LK. Competitive base-induced .alpha.-elimination and methanolysis of N-aryl-O-pivaloylhydroxylamines The Journal of Organic Chemistry. 55: 3023-3028. DOI: 10.1021/Jo00297A015 |
0.447 |
|
1989 |
Novak M, Martin KA, Heinrich JL. SN2 reactions of a carbon nucleophile with N-aryl-O-pivaloylhydroxylamines: a model for in vivo reactions of carcinogenic metabolites of aromatic amines The Journal of Organic Chemistry. 54: 5430-5431. DOI: 10.1021/Jo00284A012 |
0.377 |
|
1989 |
Panda M, Novak M, Magonski J. Hydrolysis kinetics of the ultimate hepatacarcinogen N-(sulfonatooxy)-2-(acetylamino)fluorene: detection of long-lived hydrolysis intermediates Journal of the American Chemical Society. 111: 4524-4525. DOI: 10.1021/Ja00194A072 |
0.339 |
|
1989 |
Novak M, Bonham GA, Mulero JJ, Pelecanou M, Zemis JN, Buccigross JM, Wilson TC. Hydrolysis of N-acetyl-p-benzoquinone imines: pH dependence of the partitioning of a tetrahedral intermediate Journal of the American Chemical Society. 111: 4447-4456. DOI: 10.1021/Ja00194A046 |
0.342 |
|
1989 |
Lagerman RK, Novak M. The mechanism of the interaction of N-aryl-O-pivaloylhydroxylamines with reducing metal ions Tetrahedron Letters. 30: 1923-1926. DOI: 10.1016/S0040-4039(00)99615-1 |
0.301 |
|
1988 |
Novak M, Bonham GA, Mohler LK, Peet KM. Acid-catalyzed hydrolysis of N-hydroxyacetanilides: amide hydrolysis versus nitrogen-oxygen bond heterolysis The Journal of Organic Chemistry. 53: 3903-3908. DOI: 10.1021/Jo00252A003 |
0.321 |
|
1987 |
Novak M, Rovin LH, Pelecanou M, Mulero JJ, Lagerman RK. Acid- and base-dependent hydrolysis of N-(sulfonatooxy)-3-bromoacetanilide: involvement of N-(3-bromophenyl)hydroxylamine O-sulfonate The Journal of Organic Chemistry. 52: 2002-2010. DOI: 10.1021/Jo00386A019 |
0.352 |
|
1986 |
Novak M, Pelecanou M, Zemis JN. Detection of N-acetyl-p-benzoquinone imine produced during the hydrolysis of the model phenacetin metabolite N-(pivaloyloxy)phenacetin Journal of Medicinal Chemistry. 29: 1424-1429. PMID 3735311 DOI: 10.1021/Jm00158A018 |
0.434 |
|
1986 |
Novak M, Pelecanou M, Pollack L. Hydrolysis of the model carcinogen N-(pivaloyloxy)-4-methoxyacetanilide: involvement of N-acetyl-p-benzoquinone imine Journal of the American Chemical Society. 108: 112-120. DOI: 10.1002/Chin.198619103 |
0.351 |
|
1985 |
Novak M, Roy AK. Hydrolysis of n-(pivaloyloxy)-p-acetotoluidide: nitrogen-oxygen bond cleavage reactions of a model proximate carcinogen The Journal of Organic Chemistry. 50: 4884-4888. DOI: 10.1021/Jo00224A047 |
0.342 |
|
1985 |
Novak M, Zemis JN. Arylation of diethyl phosphate by N-(sulfonatooxy)acetanilides: a model for a possible in vivo reaction of carcinogenic metabolites of aromatic amides The Journal of Organic Chemistry. 50: 4661-4663. DOI: 10.1002/Chin.198618148 |
0.377 |
|
1985 |
Pelecanou M, Novak M. Oxidation-reduction reactions of N-sulfonoxyacetanilides: mechanisms of the halide-induced reduction of models for the carcinogenic metabolites of aromatic amides Journal of the American Chemical Society. 107: 4499-4503. DOI: 10.1002/Chin.198546084 |
0.345 |
|
1985 |
Novak M, Roy AK. Hydrolysis of N-(sulfonatooxy)-p-acetotoluidide: solution chemistry of models for carcinogenic metabolites of aromatic amides The Journal of Organic Chemistry. 50: 571-580. DOI: 10.1002/Chin.198531169 |
0.333 |
|
1984 |
Novak M, Roy KR. Solvolysis of .alpha.-arylvinyl ethyl phosphates in aqueous and methanolic solutions: intramolecular participation by the [(ethyloxy)phosphoryl]oxy group Journal of Organic Chemistry. 49: 4584-4590. DOI: 10.1021/Jo00198A003 |
0.317 |
|
1980 |
Novak M, Miller A, Bruice TC, Tollin G. The mechanism of flavin 4a substitution which accompanies photolytic decarboxylation of .alpha.-substituted acetic acids. Carbanion vs. radical intermediates Journal of the American Chemical Society. 102: 1465-1467. DOI: 10.1021/Ja00524A063 |
0.388 |
|
1977 |
Novak M, Loudon GM. The hydrolysis of .alpha.-acetoxystyrenes. Kinetics and investigations of oxygen-18 exchange The Journal of Organic Chemistry. 42: 2499-2504. DOI: 10.1021/Jo00434A033 |
0.395 |
|
1976 |
Novak M, Loudon GM. Aminolysis of .alpha.-acetoxystyrenes. The pKa of acetophenones in aqueous solution Journal of the American Chemical Society. 98: 3591-3597. DOI: 10.1021/Ja00428A033 |
0.322 |
|
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