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Christopher G. Earnhart, Ph.D. - Publications

Affiliations: 
2004 College of William and Mary, Williamsburg, VA 
Area:
Microbiology Biology, Immunology, Animal Pathology Agriculture
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12/28 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 House RV, Broge TA, Suscovich TJ, Snow DM, Tomic MT, Nonet G, Bajwa K, Zhu G, Martinez Z, Hackett K, Earnhart CG, Dorsey NM, Hopkins SA, Natour DS, Davis HD, et al. Evaluation of strategies to modify Anti-SARS-CoV-2 monoclonal antibodies for optimal functionality as therapeutics. Plos One. 17: e0267796. PMID 35657812 DOI: 10.1371/journal.pone.0267796  0.35
2022 Cobb RR, Nkolola J, Gilchuk P, Chandrashekar A, Yu J, House RV, Earnhart CG, Dorsey NM, Hopkins SA, Snow DM, Chen RE, VanBlargan LA, Hechenblaickner M, Hoppe B, Collins L, et al. A combination of two human neutralizing antibodies prevents SARS-CoV-2 infection in cynomolgus macaques. Med (New York, N.Y.). PMID 35132398 DOI: 10.1016/j.medj.2022.01.004  0.305
2019 Izac JR, Camire AC, Earnhart CG, Embers ME, Funk RA, Breitschwerdt EB, Marconi RT. Analysis of the antigenic determinants of the OspC protein of the Lyme disease spirochetes: Evidence that the C10 motif is not immunodominant or required to elicit bactericidal antibody responses. Vaccine. PMID 30922701 DOI: 10.1016/J.Vaccine.2019.02.007  0.351
2016 Oliver LD, Earnhart CG, Virginia-Rhodes D, Theisen M, Marconi RT. Antibody profiling of canine IgG responses to the OspC protein of the Lyme disease spirochetes supports a multivalent approach in vaccine and diagnostic assay development. Veterinary Journal (London, England : 1997). 218: 27-33. PMID 27938705 DOI: 10.1016/J.Tvjl.2016.11.001  0.343
2012 Wagner B, Freer H, Rollins A, Garcia-Tapia D, Erb HN, Earnhart C, Marconi R, Meeus P. Antibodies to Borrelia burgdorferi OspA, OspC, OspF, and C6 antigens as markers for early and late infection in dogs. Clinical and Vaccine Immunology : Cvi. 19: 527-35. PMID 22336289 DOI: 10.1128/Cvi.05653-11  0.428
2007 Earnhart CG, Marconi RT. Construction and analysis of variants of a polyvalent Lyme disease vaccine: approaches for improving the immune response to chimeric vaccinogens. Vaccine. 25: 3419-27. PMID 17239505 DOI: 10.1016/J.Vaccine.2006.12.051  0.312
2005 Earnhart CG, Buckles EL, Dumler JS, Marconi RT. Demonstration of OspC type diversity in invasive human lyme disease isolates and identification of previously uncharacterized epitopes that define the specificity of the OspC murine antibody response. Infection and Immunity. 73: 7869-77. PMID 16299277 DOI: 10.1128/Iai.73.12.7869-7877.2005  0.389
2005 Earnhart CG, Kaattari SL. Potential novel epitopes in the extracellular products of oyster homogenate-supplemented Perkinsus marinus cells are not detected by subtractive immunization. The Journal of Parasitology. 91: 689-91. PMID 16108568 DOI: 10.1645/Ge-3427Rn  0.622
2005 Earnhart CG, Gauthier DT, Vogelbein WK, Kaattari SL. Monoclonal antibody analysis of Perkinsus marinus extracellular products. International Journal For Parasitology. 35: 171-84. PMID 15710438 DOI: 10.1016/J.Ijpara.2004.10.025  0.597
2004 Earnhart CG, Vogelbein MA, Brown GD, Reece KS, Kaattari SL. Supplementation of Perkinsus marinus cultures with host plasma or tissue homogenate enhances their infectivity. Applied and Environmental Microbiology. 70: 421-31. PMID 14711671 DOI: 10.1128/Aem.70.1.421-431.2004  0.588
2003 Earnhart CG, Kaattari SL. The humoral response to in vitro generated parasite antigens is enhanced by the removal of a defined media component prior to immunization. Journal of Immunological Methods. 278: 67-78. PMID 12957397 DOI: 10.1016/S0022-1759(03)00227-8  0.613
2003 MacIntyre EA, Earnhart CG, Kaattari SL. Host oyster tissue extracts modulate in vitro protease expression and cellular differentiation in the protozoan parasite, Perkinsus marinus. Parasitology. 126: 293-302. PMID 12741508 DOI: 10.1017/S003118200200286X  0.575
Low-probability matches (unlikely to be authored by this person)
2013 Rhodes DV, Earnhart CG, Mather TN, Meeus PF, Marconi RT. Identification of Borrelia burgdorferi ospC genotypes in canine tissue following tick infestation: implications for Lyme disease vaccine and diagnostic assay design. Veterinary Journal (London, England : 1997). 198: 412-8. PMID 23962611 DOI: 10.1016/J.Tvjl.2013.07.019  0.298
2020 Izac JR, O'Bier NS, Oliver LD, Camire AC, Earnhart CG, LeBlanc Rhodes DV, Young BF, Parnham SR, Davies C, Marconi RT. Development and optimization of OspC chimeritope vaccinogens for Lyme disease. Vaccine. PMID 31959423 DOI: 10.1016/J.Vaccine.2020.01.027  0.286
2007 Earnhart CG, Buckles EL, Marconi RT. Development of an OspC-based tetravalent, recombinant, chimeric vaccinogen that elicits bactericidal antibody against diverse Lyme disease spirochete strains. Vaccine. 25: 466-80. PMID 16996663 DOI: 10.1016/J.Vaccine.2006.07.052  0.284
2014 Earnhart CG, Rhodes DV, Smith AA, Yang X, Tegels B, Carlyon JA, Pal U, Marconi RT. Assessment of the potential contribution of the highly conserved C-terminal motif (C10) of Borrelia burgdorferi outer surface protein C in transmission and infectivity. Pathogens and Disease. 70: 176-84. PMID 24376161 DOI: 10.1111/2049-632X.12119  0.277
2006 Buckles EL, Earnhart CG, Marconi RT. Analysis of antibody response in humans to the type A OspC loop 5 domain and assessment of the potential utility of the loop 5 epitope in Lyme disease vaccine development. Clinical and Vaccine Immunology : Cvi. 13: 1162-5. PMID 17028218 DOI: 10.1128/Cvi.00099-06  0.276
2007 Earnhart CG, Marconi RT. An octavalent lyme disease vaccine induces antibodies that recognize all incorporated OspC type-specific sequences. Human Vaccines. 3: 281-9. PMID 17921702 DOI: 10.4161/Hv.4661  0.259
2017 Izac JR, Oliver LD, Earnhart CG, Marconi RT. Identification of a defined linear epitope in the OspA protein of the Lyme disease spirochetes that elicits bactericidal antibody responses: Implications for vaccine development. Vaccine. PMID 28479174 DOI: 10.1016/J.Vaccine.2017.04.079  0.24
2011 Earnhart CG, Rhodes DV, Marconi RT. Disulfide-mediated oligomer formation in Borrelia burgdorferi outer surface protein C, a critical virulence factor and potential Lyme disease vaccine candidate. Clinical and Vaccine Immunology : Cvi. 18: 901-6. PMID 21525304 DOI: 10.1128/Cvi.05004-11  0.231
2011 Fine LM, Earnhart CG, Marconi RT. Genetic transformation of the relapsing fever spirochete Borrelia hermsii: stable integration and expression of green fluorescent protein from linear plasmid 200. Journal of Bacteriology. 193: 3241-5. PMID 21551306 DOI: 10.1128/Jb.05037-11  0.228
2014 Fine LM, Miller DP, Mallory KL, Tegels BK, Earnhart CG, Marconi RT. The Borrelia hermsii factor H binding protein FhbA is not required for infectivity in mice or for resistance to human complement in vitro. Infection and Immunity. 82: 3324-32. PMID 24866803 DOI: 10.1128/Iai.01892-14  0.226
2019 Tomic MT, Espinoza Y, Martinez Z, Pham K, Cobb RR, Snow DM, Earnhart CG, Pals T, Syar ES, Niemuth N, Kobs DJ, Farr-Jones S, Marks JD. Monoclonal Antibody Combinations Prevent Serotype A and Serotype B Inhalational Botulism in a Guinea Pig Model. Toxins. 11. PMID 30959899 DOI: 10.3390/toxins11040208  0.224
2010 Earnhart CG, Leblanc DV, Alix KE, Desrosiers DC, Radolf JD, Marconi RT. Identification of residues within ligand-binding domain 1 (LBD1) of the Borrelia burgdorferi OspC protein required for function in the mammalian environment. Molecular Microbiology. 76: 393-408. PMID 20199597 DOI: 10.1111/J.1365-2958.2010.07103.X  0.186
2019 Caimano MJ, Groshong AM, Belperron A, Mao J, Hawley KL, Luthra A, Graham DE, Earnhart CG, Marconi RT, Bockenstedt LK, Blevins JS, Radolf JD. The RpoS Gatekeeper in : An Invariant Regulatory Scheme That Promotes Spirochete Persistence in Reservoir Hosts and Niche Diversity. Frontiers in Microbiology. 10: 1923. PMID 31507550 DOI: 10.3389/Fmicb.2019.01923  0.186
2007 Earnhart CG, Marconi RT. OspC phylogenetic analyses support the feasibility of a broadly protective polyvalent chimeric Lyme disease vaccine. Clinical and Vaccine Immunology : Cvi. 14: 628-34. PMID 17360854 DOI: 10.1128/Cvi.00409-06  0.159
2020 Player RA, Verratti KJ, Grady SL, Beck LC, Goodwin BG, Earnhart CG, Sozhamannan S. Complete Genome Sequence of Francisella tularensis Live Vaccine Strain NR-28537 (BEI Master Cell Bank). Microbiology Resource Announcements. 9. PMID 33303672 DOI: 10.1128/MRA.01248-20  0.057
2009 Earnhart CG, Marconi RT. Lyme Disease Vaccines For Biodefense and Emerging and Neglected Diseases. 1031-1060. DOI: 10.1016/B978-0-12-369408-9.00052-4  0.027
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