Bettina Winckler - Publications

University of Virginia, Charlottesville, VA 
Neuroscience Biology, Cell Biology

58 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Yap CC, Digilio L, McMahon LP, Wang T, Winckler B. Dynein Is Required for Rab7-Dependent Endosome Maturation, Retrograde Dendritic Transport, and Degradation. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 42: 4415-4434. PMID 35474277 DOI: 10.1523/JNEUROSCI.2530-21.2022  0.384
2022 Yap CC, Mason AJ, Winckler B. Dynamics and distribution of endosomes and lysosomes in dendrites. Current Opinion in Neurobiology. 74: 102537. PMID 35398663 DOI: 10.1016/j.conb.2022.102537  0.487
2022 Yap CC, Winckler B. Spatial regulation of endosomes in growing dendrites. Developmental Biology. 486: 5-14. PMID 35306006 DOI: 10.1016/j.ydbio.2022.03.004  0.529
2021 Yap CC, Winckler B. Lysosomes to the rescue: Anterograde axonal lysosome transport and neuronal proteostasis. Developmental Cell. 56: 1361-1362. PMID 34004149 DOI: 10.1016/j.devcel.2021.04.024  0.451
2020 Bott CJ, McMahon LP, Keil JM, Yap CC, Kwan KY, Winckler B. Nestin selectively facilitates the phosphorylation of the Lissencephaly-linked protein doublecortin (DCX) by cdk5/p35 to regulate growth cone morphology and Sema3a sensitivity in developing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 32273484 DOI: 10.1523/Jneurosci.2471-19.2020  0.521
2020 Bott CJ, Winckler B. Intermediate Filaments in Developing Neurons: Beyond Structure. Cytoskeleton (Hoboken, N.J.). PMID 31970897 DOI: 10.1002/Cm.21597  0.607
2019 Yong Y, Gamage K, Cheng I, Barford K, Spano A, Winckler B, Deppmann C. p75NTR and DR6 regulate distinct phases of axon degeneration demarcated by spheroid rupture. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. PMID 31628183 DOI: 10.1523/Jneurosci.1867-19.2019  0.508
2019 Bott CJ, Johnson CG, Yap CC, Dwyer ND, Litwa KA, Winckler B. Nestin in immature embryonic neurons affects axon growth cone morphology and Semaphorin3a sensitivity. Molecular Biology of the Cell. mbcE18060361. PMID 30840538 DOI: 10.1091/Mbc.E18-06-0361  0.592
2019 Chander P, Kennedy MJ, Winckler B, Weick JP. Neuron-Specific Gene 2 (NSG2) Encodes an AMPA Receptor Interacting Protein That Modulates Excitatory Neurotransmission. Eneuro. 6. PMID 30680309 DOI: 10.1523/ENEURO.0292-18.2018  0.457
2018 Winckler B, Faundez V, Maday S, Cai Q, Guimas Almeida C, Zhang H. The Endolysosomal System and Proteostasis: From Development to Degeneration. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 38: 9364-9374. PMID 30381428 DOI: 10.1523/Jneurosci.1665-18.2018  0.535
2018 Yap CC, Digilio L, Kruczek K, Roszkowska M, Fu XQ, Liu JS, Winckler B. A dominant dendrite phenotype caused by the disease-associated G253D mutation in doublecortin (DCX) is not due to its endocytosis defect. The Journal of Biological Chemistry. PMID 30291144 DOI: 10.1074/Jbc.Ra118.004462  0.483
2018 Yap CC, Digilio L, McMahon LP, Garcia ADR, Winckler B. Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes. The Journal of Cell Biology. PMID 29907658 DOI: 10.1083/Jcb.201711039  0.48
2018 Barford K, Keeler A, McMahon L, McDaniel K, Yap CC, Deppmann CD, Winckler B. Transcytosis of TrkA leads to diversification of dendritic signaling endosomes. Scientific Reports. 8: 4715. PMID 29549340 DOI: 10.1038/S41598-018-23036-8  0.691
2018 Zhang H, Winckler B, Cai Q. Introduction to the special issue on membrane trafficking in neurons. Developmental Neurobiology. 78: 167-169. PMID 29453802 DOI: 10.1002/Dneu.22573  0.498
2017 Barford K, Keeler A, Deppmann C, Winckler B. TrkA Bumps into Its Future Self. Developmental Cell. 42: 557-558. PMID 28950095 DOI: 10.1016/J.Devcel.2017.09.002  0.54
2017 Casanova JE, Winckler B. A new Rab7 effector controls phosphoinositide conversion in endosome maturation. The Journal of Cell Biology. PMID 28928133 DOI: 10.1083/Jcb.201709034  0.446
2017 Yap CC, Digilio L, McMahon L, Winckler B. The endosomal neuronal proteins Nsg1/NEEP21 and Nsg2/P19 are itinerant, not resident proteins of dendritic endosomes. Scientific Reports. 7: 10481. PMID 28874679 DOI: 10.1038/S41598-017-07667-X  0.584
2017 Barford K, Yap CC, Dwyer ND, Winckler B. The related neuronal endosomal proteins NEEP21 (Nsg1) and P19 (Nsg2) have divergent expression profiles in vivo. The Journal of Comparative Neurology. PMID 28299779 DOI: 10.1002/Cne.24168  0.505
2016 Yap CC, Digilio L, McMahon L, Roszkowska M, Bott CJ, Kruczek K, Winckler B. Different doublecortin (DCX) patient alleles show distinct phenotypes in cultured neurons: evidence for divergent loss-of-function and off-pathway cellular mechanisms. The Journal of Biological Chemistry. PMID 27799303 DOI: 10.1074/Jbc.M116.760777  0.546
2016 Simons M, Winckler B. Editorial overview: Cellular neuroscience. Current Opinion in Neurobiology. 39: v-vii. PMID 27528089 DOI: 10.1016/J.Conb.2016.07.014  0.321
2016 Barford K, Deppmann C, Winckler B. The neurotrophin receptor signaling endosome: where trafficking meets signaling. Developmental Neurobiology. PMID 27503831 DOI: 10.1002/Dneu.22427  0.575
2016 Lasiecka ZM, Winckler B. Studying endosomes in cultured neurons by live-cell imaging. Methods in Cell Biology. 131: 389-408. PMID 26794525 DOI: 10.1016/Bs.Mcb.2015.07.002  0.806
2015 Digilio L, Yap CC, Winckler B. Ctip2-, Satb2-, Prox1-, and GAD65-Expressing Neurons in Rat Cultures: Preponderance of Single- and Double-Positive Cells, and Cell Type-Specific Expression of Neuron-Specific Gene Family Members, Nsg-1 (NEEP21) and Nsg-2 (P19). Plos One. 10: e0140010. PMID 26465886 DOI: 10.1371/Journal.Pone.0140010  0.499
2015 Yap CC, Winckler B. Adapting for endocytosis: roles for endocytic sorting adaptors in directing neural development. Frontiers in Cellular Neuroscience. 9: 119. PMID 25904845 DOI: 10.3389/Fncel.2015.00119  0.389
2015 Digilio L, Yap CC, Winckler B. Ctip2-, Satb2-, Prox1-, and GAD65-expressing neurons in rat cultures: Preponderance of single- and double-positive cells, and cell type-specific expression of neuron-specific gene family members, Nsg-1 (NEEP21) and Nsg-2 (P19) Plos One. 10. DOI: 10.1371/journal.pone.0140010  0.402
2015 Lasiecka ZM, Winckler B. Studying endosomes in cultured neurons by live-cell imaging Methods in Cell Biology. DOI: 10.1016/bs.mcb.2015.07.002  0.801
2014 Lasiecka ZM, Yap CC, Katz J, Winckler B. Maturational conversion of dendritic early endosomes and their roles in L1-mediated axon growth. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 14633-43. PMID 25355216 DOI: 10.1523/Jneurosci.1837-14.2014  0.846
2014 Dey D, Eckle VS, Vitko I, Sullivan KA, Lasiecka ZM, Winckler B, Stornetta RL, Williamson JM, Kapur J, Perez-Reyes E. A potassium leak channel silences hyperactive neurons and ameliorates status epilepticus. Epilepsia. 55: 203-13. PMID 24299204 DOI: 10.1111/Epi.12472  0.77
2014 Eckle VS, Shcheglovitov A, Vitko I, Dey D, Yap CC, Winckler B, Perez-Reyes E. Mechanisms by which a CACNA1H mutation in epilepsy patients increases seizure susceptibility. The Journal of Physiology. 592: 795-809. PMID 24277868 DOI: 10.1113/Jphysiol.2013.264176  0.381
2013 Yap C, Winckler B. Acid Indigestion in the Endosome: Linking Signaling Dysregulation to Neurodevelopmental Disorders Neuron. 80: 4-6. PMID 24094097 DOI: 10.1016/J.Neuron.2013.09.018  0.438
2013 Fu X, Brown KJ, Yap CC, Winckler B, Jaiswal JK, Liu JS. Doublecortin (Dcx) family proteins regulate filamentous actin structure in developing neurons. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 33: 709-21. PMID 23303949 DOI: 10.1523/Jneurosci.4603-12.2013  0.518
2012 Yap CC, Vakulenko M, Kruczek K, Motamedi B, Digilio L, Liu JS, Winckler B. Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 32: 7439-53. PMID 22649224 DOI: 10.1523/Jneurosci.5318-11.2012  0.798
2012 Yap CC, Winckler B. Harnessing the Power of the Endosome to Regulate Neural Development Neuron. 74: 440-451. PMID 22578496 DOI: 10.1016/J.Neuron.2012.04.015  0.519
2011 Lasiecka ZM, Winckler B. Mechanisms of polarized membrane trafficking in neurons - Focusing in on endosomes Molecular and Cellular Neuroscience. 48: 278-287. PMID 21762782 DOI: 10.1016/J.Mcn.2011.06.013  0.841
2011 Winckler B, Choo Yap C. Endocytosis and Endosomes at the Crossroads of Regulating Trafficking of Axon Outgrowth-Modifying Receptors Traffic. 12: 1099-1108. PMID 21535338 DOI: 10.1111/J.1600-0854.2011.01213.X  0.621
2010 Lasiecka ZM, Yap CC, Caplan S, Winckler B. Neuronal early endosomes require EHD1 for L1/NgCAM trafficking. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 16485-97. PMID 21147988 DOI: 10.1523/Jneurosci.3127-10.2010  0.848
2010 Winckler B. Bettina Winckler: neuronal polarity on her mind. Interviewed by Caitlin Sedwick. The Journal of Cell Biology. 191: 4-5. PMID 20921132 DOI: 10.1083/jcb.1911pi  0.368
2010 Dwyer ND, Winckler B. TGF-beta receptors PAR-ticipate in axon formation. Cell. 142: 21-3. PMID 20603011 DOI: 10.1016/J.Cell.2010.06.024  0.56
2010 Winckler B, Mellman I. Trafficking guidance receptors. Cold Spring Harbor Perspectives in Biology. 2: a001826. PMID 20504966 DOI: 10.1101/Cshperspect.A001826  0.507
2010 Yap CC, Lasiecka ZM, Caplan S, Winckler B. Alterations of EHD1/EHD4 protein levels interfere with L1/NgCAM endocytosis in neurons and disrupt axonal targeting. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 30: 6646-57. PMID 20463227 DOI: 10.1523/Jneurosci.5428-09.2010  0.847
2010 Yap CC, Winckler B. Vesicular Sorting to Axons and Dendrites Encyclopedia of Neuroscience. 115-120. DOI: 10.1016/B978-008045046-9.00743-9  0.602
2008 Lasiecka ZM, Yap CC, Vakulenko M, Winckler B. Chapter 7 Compartmentalizing the Neuronal Plasma Membrane. From Axon Initial Segments to Synapses International Review of Cell and Molecular Biology. 272: 303-389. PMID 19121821 DOI: 10.1016/S1937-6448(08)01607-9  0.768
2008 Yap CC, Nokes RL, Wisco D, Anderson E, Fölsch H, Winckler B. Pathway selection to the axon depends on multiple targeting signals in NgCAM. Journal of Cell Science. 121: 1514-25. PMID 18411247 DOI: 10.1242/Jcs.022442  0.59
2008 Yap CC, Wisco D, Kujala P, Lasiecka ZM, Cannon JT, Chang MC, Hirling H, Klumperman J, Winckler B. The somatodendritic endosomal regulator NEEP21 facilitates axonal targeting of L1/NgCAM. The Journal of Cell Biology. 180: 827-42. PMID 18299352 DOI: 10.1083/Jcb.200707143  0.844
2007 Thompson A, Nessler R, Wisco D, Anderson E, Winckler B, Sheff D. Recycling endosomes of polarized epithelial cells actively sort apical and basolateral cargos into separate subdomains Molecular Biology of the Cell. 18: 2687-2697. PMID 17494872 DOI: 10.1091/Mbc.E05-09-0873  0.38
2007 Winckler B. BDNF Instructs the Kinase LKB1 To Grow an Axon Cell. 129: 459-460. PMID 17482540 DOI: 10.1016/J.Cell.2007.04.021  0.541
2007 Boiko T, Vakulenko M, Ewers H, Yap CC, Norden C, Winckler B. Ankyrin-dependent and -independent mechanisms orchestrate axonal compartmentalization of L1 family members neurofascin and L1/neuron-glia cell adhesion molecule. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 27: 590-603. PMID 17234591 DOI: 10.1523/Jneurosci.4302-06.2007  0.791
2006 Boiko T, Winckler B. Myelin under construction -- teamwork required. The Journal of Cell Biology. 172: 799-801. PMID 16533942 DOI: 10.1083/Jcb.200602101  0.48
2006 Johnson EM, Kinoshita Y, Weinreb DB, Wortman MJ, Simon R, Khalili K, Winckler B, Gordon J. Role of Pur alpha in targeting mRNA to sites of translation in hippocampal neuronal dendrites. Journal of Neuroscience Research. 83: 929-43. PMID 16511857 DOI: 10.1002/Jnr.20806  0.353
2006 Chang MC, Wisco D, Ewers H, Norden C, Winckler B. Inhibition of sphingolipid synthesis affects kinetics but not fidelity of L1/NgCAM transport along direct but not transcytotic axonal pathways. Molecular and Cellular Neurosciences. 31: 525-38. PMID 16376103 DOI: 10.1016/J.Mcn.2005.11.006  0.566
2005 Anderson E, Maday S, Sfakianos J, Hull M, Winckler B, Sheff D, Fölsch H, Mellman I. Transcytosis of NgCAM in epithelial cells reflects differential signal recognition on the endocytic and secretory pathways. The Journal of Cell Biology. 170: 595-605. PMID 16087710 DOI: 10.1083/Jcb.200506051  0.383
2004 Winckler B. Scientiae forum/models and speculations pathway for axonal targeting of membrane proteins Biology of the Cell. 96: 669-674. PMID 15567519 DOI: 10.1016/J.Biolcel.2004.05.005  0.61
2003 Wisco D, Anderson ED, Chang MC, Norden C, Boiko T, Fölsch H, Winckler B. Uncovering multiple axonal targeting pathways in hippocampal neurons. The Journal of Cell Biology. 162: 1317-28. PMID 14517209 DOI: 10.1083/Jcb.200307069  0.563
2003 Boiko T, Winckler B. Picket and other fences in biological membranes. Developmental Cell. 5: 191-2. PMID 12919670 DOI: 10.1016/S1534-5807(03)00240-5  0.379
1999 Winckler B, Mellman I. Neuronal polarity: Controlling the sorting and diffusion of membrane components Neuron. 23: 637-640. PMID 10482229 DOI: 10.1016/S0896-6273(01)80021-0  0.327
1999 Winckler B, Forscher P, Mellman I. A diffusion barrier maintains distribution of membrane proteins in polarized neurons. Nature. 397: 698-701. PMID 10067893 DOI: 10.1038/17806  0.418
1996 Winckler B, Poo MM. No diffusion barrier at axon hillock. Nature. 379: 213. PMID 8538784 DOI: 10.1038/379213a0  0.325
1991 Birgbauer E, Dinsmore JH, Winckler B, Lander AD, Solomon F. Association of ezrin isoforms with the neuronal cytoskeleton. Journal of Neuroscience Research. 30: 232-41. PMID 1795406 DOI: 10.1002/jnr.490300124  0.384
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