James D. Otvos - Publications

Affiliations: 
North Carolina State University, Raleigh, NC 
Area:
Analytical Chemistry, Medical Biophysics, Radiology

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Year Citation  Score
2024 Westerman KE, Kilpeläinen TO, Sevilla-Gonzalez M, Connelly MA, Wood AC, Tsai MY, Taylor KD, Rich SS, Rotter JI, Otvos JD, Bentley AR, Mora S, Aschard H, Rao DC, Gu C, et al. Refinement of a published gene-physical activity interaction impacting HDL-cholesterol: role of sex and lipoprotein subfractions. Medrxiv : the Preprint Server For Health Sciences. PMID 38313294 DOI: 10.1101/2024.01.23.24301689  0.305
2022 Mietus-Snyder M, Suslovic W, Delaney M, Playford MP, Ballout RA, Barber JR, Otvos JD, DeBiasi RL, Mehta NN, Remaley AT. Changes in HDL cholesterol, particles, and function associate with pediatric COVID-19 severity. Frontiers in Cardiovascular Medicine. 9: 1033660. PMID 36312284 DOI: 10.3389/fcvm.2022.1033660  0.343
2022 Chevli PA, Islam T, Pokharel Y, Rodriguez F, Virani SS, Blaha MJ, Bertoni AG, Budoff M, Otvos JD, Shapiro MD. Association between remnant lipoprotein cholesterol, high-sensitivity C-reactive protein, and risk of atherosclerotic cardiovascular disease events in the Multi-Ethnic Study of Atherosclerosis (MESA). Journal of Clinical Lipidology. PMID 36180367 DOI: 10.1016/j.jacl.2022.09.005  0.328
2021 Ballout RA, Kong H, Sampson M, Otvos JD, Cox AL, Agbor-Enoh S, Remaley AT. The NIH Lipo-COVID Study: A Pilot NMR Investigation of Lipoprotein Subfractions and Other Metabolites in Patients with Severe COVID-19. Biomedicines. 9. PMID 34572275 DOI: 10.3390/biomedicines9091090  0.378
2020 Garcia E, Bennett DW, Connelly MA, Jeyarajah EJ, Warf FC, Shalaurova I, Matyus SP, Wolak-Dinsmore J, Oskardmay DN, Young RM, Sampson M, Remaley AT, Otvos JD. The extended lipid panel assay: a clinically-deployed high-throughput nuclear magnetic resonance method for the simultaneous measurement of lipids and Apolipoprotein B. Lipids in Health and Disease. 19: 247. PMID 33261644 DOI: 10.1186/s12944-020-01424-2  0.366
2020 Bedi S, Garcia E, Jeyarajah EJ, Shalaurova I, Perez-Matos MC, Jiang ZG, Dullaart RPF, Matyus SP, Kirk WJ, Otvos JD, Davidson WS, Connelly MA. Characterization of LP-Z Lipoprotein Particles and Quantification in Subjects with Liver Disease Using a Newly Developed NMR-Based Assay. Journal of Clinical Medicine. 9. PMID 32927635 DOI: 10.3390/Jcm9092915  0.354
2020 Flores-Guerrero JL, Gruppen EG, Connelly MA, Shalaurova I, Otvos JD, Garcia E, Bakker SJL, Dullaart RPF. A Newly Developed Diabetes Risk Index, Based on Lipoprotein Subfractions and Branched Chain Amino Acids, is Associated with Incident Type 2 Diabetes Mellitus in the PREVEND Cohort. Journal of Clinical Medicine. 9: 2781. PMID 32867285 DOI: 10.3390/Jcm9092781  0.402
2020 Singh K, Chandra A, Sperry T, Joshi PH, Khera A, Virani SS, Ballantyne CM, Otvos JD, Dullaart RPF, Gruppen EG, Connelly MA, Ayers CR, Rohatgi A. Associations Between High-Density Lipoprotein Particles and Ischemic Events by Vascular Domain, Sex, and Ethnicity: A Pooled Cohort Analysis. Circulation. 142: 657-669. PMID 32804568 DOI: 10.1161/Circulationaha.120.045713  0.462
2020 Sampson M, Ling C, Sun Q, Harb R, Ashmaig M, Warnick R, Sethi A, Fleming JK, Otvos JD, Meeusen JW, Delaney SR, Jaffe AS, Shamburek R, Amar M, Remaley AT. A New Equation for Calculation of Low-Density Lipoprotein Cholesterol in Patients With Normolipidemia and/or Hypertriglyceridemia. Jama Cardiology. PMID 32101259 DOI: 10.1001/Jamacardio.2020.0013  0.426
2020 Remaley AT, Otvos JD. Methodological issues regarding: "A third of nonfasting plasma cholesterol is in remnant lipoproteins: Lipoprotein subclass profiling in 9293 individuals". Atherosclerosis. 302: 55-56. PMID 32029245 DOI: 10.1016/J.Atherosclerosis.2020.01.020  0.411
2020 Garcia E, Shalaurova I, Matyus SP, Oskardmay DN, Otvos JD, Dullaart RPF, Connelly MA. Ketone Bodies Are Mildly Elevated in Subjects with Type 2 Diabetes Mellitus and Are Inversely Associated with Insulin Resistance as Measured by the Lipoprotein Insulin Resistance Index. Journal of Clinical Medicine. 9. PMID 31979327 DOI: 10.3390/Jcm9020321  0.32
2020 Katz LE, Otvos JD, Drews K, Tesfaldet B, Bacha F, Willi SM, Marcovina SM, Mckay S, Weinstock RS. 59-OR: Lipoprotein Particle Distribution by NMR in Youth with Type 2 Diabetes (T2D) in the TODAY Study Diabetes. 69. DOI: 10.2337/Db20-59-Or  0.367
2020 Flores-Guerrero JL, Connelly MA, Shalaurova IY, Gruppen EG, Otvos JD, Dullaart RPF, Bakker SJI. 1437-P: A Newly Developed Diabetes Risk Index, Based on Lipoprotein Subfractions and Branched-Chain Amino Acids, Is Associated with Incident Type 2 Diabetes Mellitus in the PREVEND Cohort Diabetes. 69. DOI: 10.2337/Db20-1437-P  0.313
2020 Chung ST, Matta S, Meyers A, Cravalho CK, Villalobos-Perez A, Mabundo L, Courville AB, Sampson ML, Otvos JD, Magge SN. 1243-P: NMR-Derived Biomarkers Identify Cardiometabolic Disease Risk in Youth Diabetes. 69. DOI: 10.2337/Db20-1243-P  0.306
2019 Lamprea-Montealegre JA, McClelland RL, Otvos JD, Mora S, Koch M, Jensen MK, de Boer IH. Association of High-Density Lipoprotein Particles and High-Density Lipoprotein Apolipoprotein C-III Content With Cardiovascular Disease Risk According to Kidney Function: The Multi-Ethnic Study of Atherosclerosis. Journal of the American Heart Association. 8: e013713. PMID 31818211 DOI: 10.1161/Jaha.119.013713  0.427
2019 Garcia E, Osté MCJ, Bennett DW, Jeyarajah EJ, Shalaurova I, Gruppen EG, Hazen SL, Otvos JD, Bakker SJL, Dullaart RPF, Connelly MA. High Betaine, a Trimethylamine N-Oxide Related Metabolite, Is Prospectively Associated with Low Future Risk of Type 2 Diabetes Mellitus in the PREVEND Study. Journal of Clinical Medicine. 8. PMID 31683780 DOI: 10.3390/Jcm8111813  0.352
2019 Fashanu OE, Oyenuga AO, Zhao D, Tibuakuu M, Mora S, Otvos JD, Stein JH, Michos ED. GlycA, a Novel Inflammatory Marker and Its Association With Peripheral Arterial Disease and Carotid Plaque: The Multi-Ethnic Study of Atherosclerosis. Angiology. 3319719845185. PMID 31030528 DOI: 10.1177/0003319719845185  0.329
2019 Schutten JC, Gomes-Neto AW, Navis G, Gansevoort RT, Dullaart RPF, Kootstra-Ros JE, Danel RM, Goorman F, Gans ROB, de Borst MH, Jeyarajah EJ, Shalaurova I, Otvos JD, Connelly MA, Bakker SJL. Lower Plasma Magnesium, Measured by Nuclear Magnetic Resonance Spectroscopy, is Associated with Increased Risk of Developing Type 2 Diabetes Mellitus in Women: Results from a Dutch Prospective Cohort Study. Journal of Clinical Medicine. 8. PMID 30717286 DOI: 10.3390/Jcm8020169  0.364
2019 Ezeigwe A, Fashanu OE, Zhao D, Budoff MJ, Otvos JD, Thomas IC, Mora S, Tibuakuu M, Michos ED. The novel inflammatory marker GlycA and the prevalence and progression of valvular and thoracic aortic calcification: The Multi-Ethnic Study of Atherosclerosis. Atherosclerosis. 282: 91-99. PMID 30716566 DOI: 10.1016/J.Atherosclerosis.2019.01.011  0.317
2018 Flores-Guerrero JL, Osté MCJ, Kieneker LM, Gruppen EG, Wolak-Dinsmore J, Otvos JD, Connelly MA, Bakker SJL, Dullaart RPF. Plasma Branched-Chain Amino Acids and Risk of Incident Type 2 Diabetes: Results from the PREVEND Prospective Cohort Study. Journal of Clinical Medicine. 7: 513. PMID 30518023 DOI: 10.3390/Jcm7120513  0.348
2018 Benson EA, Tibuakuu M, Zhao D, Akinkuolie AO, Otvos JD, Duprez DA, Jacobs DR, Mora S, Michos ED. Associations of ideal cardiovascular health with GlycA, a novel inflammatory marker: The Multi-Ethnic Study of Atherosclerosis. Clinical Cardiology. PMID 30452775 DOI: 10.1002/Clc.23069  0.339
2018 Delatour V, Clouet-Foraison N, Gaie-Levrel F, Marcovina SM, Hoofnagle AN, Kuklenyik Z, Caulfield MP, Otvos JD, Krauss RM, Kulkarni KR, Contois JH, Remaley AT, Vesper HW, Cobbaert CM, Gillery P. Comparability of Lipoprotein Particle Number Concentrations Across ES-DMA, NMR, LC-MS/MS, Immunonephelometry, and VAP: In Search of a Candidate Reference Measurement Procedure for apoB and non-HDL-P Standardization. Clinical Chemistry. PMID 30087138 DOI: 10.1373/Clinchem.2018.288746  0.42
2018 Muhlestein JB, May HT, Galenko O, Knowlton KU, Otvos JD, Connelly MA, Lappe DL, Anderson JL. GlycA and hsCRP are independent and additive predictors of future cardiovascular events among patients undergoing angiography: The intermountain heart collaborative study. American Heart Journal. 202: 27-32. PMID 29803983 DOI: 10.1016/J.Ahj.2018.04.003  0.327
2018 Wolak-Dinsmore J, Gruppen EG, Shalaurova I, Matyus SP, Grant RP, Gegen R, Bakker SJL, Otvos JD, Connelly MA, Dullaart RPF. A novel NMR-based assay to measure circulating concentrations of branched-chain amino acids: Elevation in subjects with type 2 diabetes mellitus and association with carotid intima media thickness. Clinical Biochemistry. PMID 29432757 DOI: 10.1016/J.Clinbiochem.2018.02.001  0.334
2018 Otvos JD, Guyton JR, Connelly MA, Akapame S, Bittner V, Kopecky SL, Lacy M, Marcovina SM, Muhlestein JB, Boden WE. Relations of GlycA and lipoprotein particle subspecies with cardiovascular events and mortality: A post hoc analysis of the AIM-HIGH trial. Journal of Clinical Lipidology. 12: 348. PMID 29409728 DOI: 10.1016/J.Jacl.2018.01.002  0.493
2017 Weiss R, Nassar H, Sinnreich R, Ahmad WA, Otvos J, Kark JD. Palestinian Arab ethnicity is associated with an adverse metabolic phenotype. Clinica Chimica Acta; International Journal of Clinical Chemistry. PMID 28987777 DOI: 10.1016/J.Cca.2017.10.004  0.43
2017 Davidson WS, Heink A, Sexmith H, Dolan LM, Gordon SM, Otvos JD, Melchior JT, Elder DA, Khoury J, Geh E, Shah AS. Obesity is Associated with an Altered HDL Subspecies Profile Among Adolescents with Metabolic Disease. Journal of Lipid Research. PMID 28743729 DOI: 10.1194/Jlr.M078667  0.326
2017 Garcia E, Wolak-Dinsmore J, Wang Z, Li XS, Bennett DW, Connelly MA, Otvos JD, Hazen SL, Jeyarajah EJ. NMR quantification of trimethylamine-N-oxide in human serum and plasma in the clinical laboratory setting. Clinical Biochemistry. PMID 28624482 DOI: 10.1016/J.Clinbiochem.2017.06.003  0.36
2017 Orchard TJ, Cariou B, Connelly MA, Otvos JD, Zhang S, Antalis CJ, Ivanyi T, Hoogwerf BJ. The effects of basal insulin peglispro vs. insulin glargine on lipoprotein particles by NMR and liver fat content by MRI in patients with diabetes. Cardiovascular Diabetology. 16: 73. PMID 28587667 DOI: 10.1186/S12933-017-0555-1  0.33
2017 AbouAssi H, Connelly MA, Bateman LA, Tune KN, Huebner JL, Kraus VB, Winegar DA, Otvos JD, Kraus WE, Huffman KM. Does a lack of physical activity explain the rheumatoid arthritis lipid profile? Lipids in Health and Disease. 16: 39. PMID 28187765 DOI: 10.1186/S12944-017-0427-4  0.457
2017 Gomaraschi M, Kempen H, Simonelli S, Calabresi L, Moerland M, Otvos J, Jeyarajah E, Kallend D, Wijngaard P. Effects of a single infusion of synthetic HDL containing apoA-IMilano (MDCO-216) in healthy volunteers and stable coronary artery disease patients Nutrition Metabolism and Cardiovascular Diseases. 27. DOI: 10.1016/J.Numecd.2016.11.066  0.329
2016 Kempen HJ, Gomaraschi M, Simonelli S, Calabresi L, Moerland M, Otvos J, Jeyarajah E, Kallend D, Wijngaard PLJ. Persistent changes in lipoprotein lipids after a single infusion of ascending doses of MDCO-216 (apoA-IMilano/POPC) in healthy volunteers and stable coronary artery disease patients Atherosclerosis. 255: 17-24. PMID 27816804 DOI: 10.1016/J.Atherosclerosis.2016.10.042  0.411
2016 May HT, Anderson JL, Winegar DA, Rollo J, Connelly MA, Otvos JD, Muhlestein JB. Utility of high density lipoprotein particle concentration in predicting future major adverse cardiovascular events among patients undergoing angiography. Clinical Biochemistry. PMID 27616009 DOI: 10.1016/J.Clinbiochem.2016.09.004  0.472
2016 Connelly MA, Shimizu C, Winegar DA, Shalaurova I, Pourfarzib R, Otvos JD, Kanegaye JT, Tremoulet AH, Burns JC. Differences in GlycA and lipoprotein particle parameters may help distinguish acute kawasaki disease from other febrile illnesses in children. Bmc Pediatrics. 16: 151. PMID 27596163 DOI: 10.1186/S12887-016-0688-5  0.36
2016 Ditah C, Otvos J, Nassar H, Shaham D, Sinnreich R, Kark JD. Small and medium sized HDL particles are protectively associated with coronary calcification in a cross-sectional population-based sample. Atherosclerosis. 251: 124-131. PMID 27318832 DOI: 10.1016/J.Atherosclerosis.2016.06.010  0.493
2016 Connelly MA, Gruppen EG, Otvos JD, Dullaart RP. Inflammatory glycoproteins in cardiometabolic disorders, autoimmune diseases and cancer. Clinica Chimica Acta; International Journal of Clinical Chemistry. 459: 177-186. PMID 27312321 DOI: 10.1016/J.Cca.2016.06.012  0.315
2016 Gruppen EG, Connelly MA, Vart P, Otvos JD, Bakker SJ, Dullaart RP. GlycA, a novel proinflammatory glycoprotein biomarker, and high-sensitivity C-reactive protein are inversely associated with sodium intake after controlling for adiposity: the Prevention of Renal and Vascular End-Stage Disease study. The American Journal of Clinical Nutrition. PMID 27305953 DOI: 10.3945/Ajcn.116.133744  0.339
2016 Kim DS, Li YK, Bell GA, Burt AA, Vaisar T, Hutchins PM, Furlong CE, Otvos JD, Polak JF, Arnan MK, Kaufman JD, McClelland RL, Longstreth WT, Jarvik GP. Concentration of Smaller High-Density Lipoprotein Particle (HDL-P) Is Inversely Correlated With Carotid Intima Media Thickening After Confounder Adjustment: The Multi Ethnic Study of Atherosclerosis (MESA). Journal of the American Heart Association. 5. PMID 27207961 DOI: 10.1161/Jaha.115.002977  0.507
2016 Tehrani DM, Zhao Y, Blaha MJ, Mora S, Mackey RH, Michos ED, Budoff MJ, Cromwell W, Otvos JD, Rosenblit PD, Wong ND. Discordance of Low-Density Lipoprotein and High-Density Lipoprotein Cholesterol Particle Versus Cholesterol Concentration for the Prediction of Cardiovascular Disease in Patients With Metabolic Syndrome and Diabetes Mellitus (from the Multi-Ethnic Study of Atherosclerosis [MESA]). The American Journal of Cardiology. PMID 27156827 DOI: 10.1016/J.Amjcard.2016.03.040  0.5
2016 Kempen HJ, Asztalos BF, Moerland M, Jeyarajah E, Otvos J, Kallend DG, Bellibas SE, Wijngaard PLJ. High-Density Lipoprotein Subfractions and Cholesterol Efflux Capacities After Infusion of MDCO-216 (Apolipoprotein A-IMilano/Palmitoyl-Oleoyl-Phosphatidylcholine) in Healthy Volunteers and Stable Coronary Artery Disease Patients Arteriosclerosis, Thrombosis, and Vascular Biology. 36: 736-742. PMID 26916733 DOI: 10.1161/Atvbaha.115.307052  0.409
2016 Connelly MA, Shalaurova I, Otvos JD. High-density lipoprotein and inflammation in cardiovascular disease. Translational Research : the Journal of Laboratory and Clinical Medicine. PMID 26850902 DOI: 10.1016/J.Trsl.2016.01.006  0.471
2016 Durcan L, Winegar DA, Connelly MA, Otvos JD, Magder LS, Petri M. Longitudinal Evaluation of Lipoprotein Variables in Systemic Lupus Erythematosus Reveals Adverse Changes with Disease Activity and Prednisone and More Favorable Profiles with Hydroxychloroquine Therapy. The Journal of Rheumatology. PMID 26834214 DOI: 10.3899/Jrheum.150437  0.414
2016 Jiang ZG, Tapper EB, Connelly MA, Pimentel CM, Feldbrügge L, Kim M, Krawczyk S, Afdh Al N, Robson SC, Herman M, Otvos JD, Mukamal KJ, Lai M. Steatohepatitis and liver fibrosis are predicted by the characteristics of very low density lipoprotein in nonalcoholic fatty liver disease. Liver International : Official Journal of the International Association For the Study of the Liver. PMID 26815314 DOI: 10.1111/Liv.13076  0.39
2016 Durcan L, Arbab-Zadeh A, Connelly M, Otvos J, Magder LS, Petri M. THU0339 Non-Calcified Coronary Artery Plaque Associates with Adverse Lipoprotein Profiles in Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. 75: 309-310. DOI: 10.1136/Annrheumdis-2016-Eular.3708  0.444
2015 Gruppen EG, Riphagen IJ, Connelly MA, Otvos JD, Bakker SJ, Dullaart RP. GlycA, a Pro-Inflammatory Glycoprotein Biomarker, and Incident Cardiovascular Disease: Relationship with C-Reactive Protein and Renal Function. Plos One. 10: e0139057. PMID 26398105 DOI: 10.1371/Journal.Pone.0139057  0.336
2015 Duprez DA, Otvos J, Tracy RP, Feingold KR, Greenland P, Gross MD, Lima JA, Mackey RH, Neaton JD, Sanchez OA, Jacobs DR. High-Density Lipoprotein Subclasses and Noncardiovascular, Noncancer Chronic Inflammatory-Related Events Versus Cardiovascular Events: The Multi-Ethnic Study of Atherosclerosis. Journal of the American Heart Association. 4: e002295. PMID 26370448 DOI: 10.1161/Jaha.115.002295  0.448
2015 Gruppen EG, Connelly MA, Otvos JD, Bakker SJ, Dullaart RP. A novel protein glycan biomarker and LCAT activity in metabolic syndrome. European Journal of Clinical Investigation. 45: 850-9. PMID 26081900 DOI: 10.1111/Eci.12481  0.421
2015 Ballantyne CM, Braeckman RA, Bays HE, Kastelein JJ, Otvos JD, Stirtan WG, Doyle RT, Soni PN, Juliano RA. Effects of icosapent ethyl on lipoprotein particle concentration and size in statin-treated patients with persistent high triglycerides (the ANCHOR Study). Journal of Clinical Lipidology. 9: 377-83. PMID 26073397 DOI: 10.1016/J.Jacl.2014.11.009  0.412
2015 Dullaart RP, Gruppen EG, Connelly MA, Otvos JD, Lefrandt JD. GlycA, a biomarker of inflammatory glycoproteins, is more closely related to the leptin/adiponectin ratio than to glucose tolerance status. Clinical Biochemistry. 48: 811-4. PMID 25977069 DOI: 10.1016/J.Clinbiochem.2015.05.001  0.319
2015 Ormseth MJ, Chung CP, Oeser AM, Connelly MA, Sokka T, Raggi P, Solus JF, Otvos JD, Stein CM. Utility of a novel inflammatory marker, GlycA, for assessment of rheumatoid arthritis disease activity and coronary atherosclerosis. Arthritis Research & Therapy. 17: 117. PMID 25956924 DOI: 10.1186/S13075-015-0646-X  0.334
2015 Sanchez OA, Duprez DA, Daniels LB, Maisel AS, Otvos JD, Peralta CA, Lima JA, Bahrami H, Jacobs DR. The association between N-terminal pro B-type natriuretic peptide and lipoprotein particle concentration plateaus at higher N-terminal pro B-type natriuretic peptide values: Multi-Ethnic Study on Atherosclerosis. Metabolism: Clinical and Experimental. 64: 857-61. PMID 25931335 DOI: 10.1016/J.Metabol.2015.04.001  0.331
2015 Otvos JD, Shalaurova I, Wolak-Dinsmore J, Connelly MA, Mackey RH, Stein JH, Tracy RP. GlycA: A Composite Nuclear Magnetic Resonance Biomarker of Systemic Inflammation. Clinical Chemistry. 61: 714-23. PMID 25779987 DOI: 10.1373/Clinchem.2014.232918  0.329
2015 Rashid S, Sniderman A, Melone M, Brown PE, Otvos JD, Mente A, Schulze K, McQueen MJ, Anand SS, Yusuf S. Elevated cholesteryl ester transfer protein (CETP) activity, a major determinant of the atherogenic dyslipidemia, and atherosclerotic cardiovascular disease in South Asians. European Journal of Preventive Cardiology. 22: 468-77. PMID 24659026 DOI: 10.1177/2047487314528461  0.343
2015 Ormseth M, Chung C, Oeser A, Connelly M, Sokka T, Raggi P, Solus J, Otvos J, Stein CM. FRI0089 Utility of a Novel Inflammatory Marker, Glyca, for Assessment of Rheumatoid Arthritis Disease Activity and Coronary Atherosclerosis Annals of the Rheumatic Diseases. 74: 452-452. DOI: 10.1136/Annrheumdis-2015-Eular.6003  0.316
2015 Durcan LJ, Winegar D, Connelly MA, Otvos J, Magder L, Petri M. FRI0406 Small LDL-P Increases with Increased Disease Activity in SLE Annals of the Rheumatic Diseases. 74: 573-573. DOI: 10.1136/Annrheumdis-2015-Eular.4310  0.459
2015 Chung C, Ormseth M, Connelly M, Oeser A, Solus J, Otvos J, Raggi P, Stein C. FRI0391 GLYCA, A Novel Marker of Inflammation, Is Elevated in Systemic Lupus Erythematosus Annals of the Rheumatic Diseases. 74: 568.3-568. DOI: 10.1136/Annrheumdis-2015-Eular.1912  0.361
2014 Kempen HJ, Schranz DB, Asztalos BF, Otvos J, Jeyarajah E, Drazul-Schrader D, Collins HL, Adelman SJ, Wijngaard PL. Incubation of MDCO-216 (ApoA-IMilano/POPC) with Human Serum Potentiates ABCA1-Mediated Cholesterol Efflux Capacity, Generates New Prebeta-1 HDL, and Causes an Increase in HDL Size. Journal of Lipids. 2014: 923903. PMID 25478232 DOI: 10.1155/2014/923903  0.447
2014 Shalaurova I, Connelly MA, Garvey WT, Otvos JD. Lipoprotein insulin resistance index: a lipoprotein particle-derived measure of insulin resistance. Metabolic Syndrome and Related Disorders. 12: 422-9. PMID 24959989 DOI: 10.1089/Met.2014.0050  0.383
2014 Dullaart RPF, Otvos JD, James RW. Serum paraoxonase-1 activity is more closely related to HDL particle concentration and large HDL particles than to HDL cholesterol in Type 2 diabetic and non-diabetic subjects Clinical Biochemistry. 47: 1022-1027. PMID 24769273 DOI: 10.1016/j.clinbiochem.2014.04.013  0.351
2014 Williams PT, Zhao XQ, Marcovina SM, Otvos JD, Brown BG, Krauss RM. Comparison of four methods of analysis of lipoprotein particle subfractions for their association with angiographic progression of coronary artery disease. Atherosclerosis. 233: 713-20. PMID 24603218 DOI: 10.1016/J.Atherosclerosis.2014.01.034  0.442
2014 Jago R, Drews KL, Otvos JD, Foster GD, Marcus MD, Buse JB, Mietus-Snyder M, Willi SM. Effect of relative weight group change on nuclear magnetic resonance spectroscopy derived lipoprotein particle size and concentrations among adolescents. The Journal of Pediatrics. 164: 1091-1098.e3. PMID 24508445 DOI: 10.1016/J.Jpeds.2013.12.029  0.347
2014 Folse H, Goswami D, Rengarajan B, Kahn R, Budoff M, Winegar D, Otvos J. Using Low-Density Lipoprotein (LDL) Particle Number (LDL-P) versus LDL Cholesterol (LDL-C) to Guide Preventative Therapy for Cardiovascular Disease Journal of Clinical Lipidology. 8: 297-298. DOI: 10.1016/J.Jacl.2014.02.016  0.487
2014 Banach M, Rysz J, Rizzo M, Otvos J, Toth P, Pencina M, Mlynarski W, Mikhailidis D. Investigating dysfunctional-hdl in selected groups of patients at high risk of cardiovascular events (dys-hdl study) - Protocol and organization Atherosclerosis. 235: e171-e172. DOI: 10.1016/J.Atherosclerosis.2014.05.496  0.358
2014 Kempen H, Schranz D, Asztalos B, Otvos J, Jeyarajah E, Drazul-Schrader D, Collins H, Adelman S. Incubation of MDCO216 with human serum potentiates ABCA1 mediated cholesterol efflux capacity and generates new prebeta-1 Hdl Atherosclerosis. 235: e45-e46. DOI: 10.1016/J.Atherosclerosis.2014.05.103  0.388
2013 Goldberg R, Temprosa M, Otvos J, Brunzell J, Marcovina S, Mather K, Arakaki R, Watson K, Horton E, Barrett-Connor E. Lifestyle and metformin treatment favorably influence lipoprotein subfraction distribution in the diabetes prevention program Journal of Clinical Endocrinology and Metabolism. 98: 3989-3998. PMID 23979954 DOI: 10.1210/Jc.2013-1452  0.326
2013 Kramer MS, Kahn SR, Dahhou M, Otvos J, Genest J, Platt RW, Evans RW. Maternal lipids and small for gestational age birth at term. The Journal of Pediatrics. 163: 983-8. PMID 23810722 DOI: 10.1016/J.Jpeds.2013.05.014  0.402
2013 Mietus-Snyder M, Drews KL, Otvos JD, Willi SM, Foster GD, Jago R, Buse JB. Low-density lipoprotein cholesterol versus particle number in middle school children. The Journal of Pediatrics. 163: 355-62. PMID 23415622 DOI: 10.1016/J.Jpeds.2013.01.012  0.474
2013 Kwiterovich PO, Virgil DG, Chu AY, Khouzami VA, Alaupovic P, Otvos JD. Interrelationships between the concentration and size of the largest high-density lipoprotein subfraction and apolipoprotein C-I in infants at birth and follow-up at 2-3 months of age and their parents. Journal of Clinical Lipidology. 7: 29-37. PMID 23351580 DOI: 10.1016/J.Jacl.2012.09.002  0.34
2013 Ballantyne CM, Braeckman R, Bays H, Kastelein J, Otvos J, Stirtan W, Soni P. Effects of Icosapent Ethyl on Lipoprotein Particle Concentration and the Fatty Acid Desaturation Index in Statin-treated Patients With Persistent High Triglycerides (the ANCHOR Study) Journal of Clinical Lipidology. 7: 270-271. DOI: 10.1016/J.Jacl.2013.03.071  0.397
2012 Bays HE, Braeckman RA, Ballantyne CM, Kastelein JJ, Otvos JD, Stirtan WG, Soni PN. Icosapent ethyl, a pure EPA omega-3 fatty acid: effects on lipoprotein particle concentration and size in patients with very high triglyceride levels (the MARINE study). Journal of Clinical Lipidology. 6: 565-72. PMID 23312052 DOI: 10.1016/J.Jacl.2012.07.001  0.43
2012 Parish S, Offer A, Clarke R, Hopewell JC, Hill MR, Otvos JD, Armitage J, Collins R. Lipids and lipoproteins and risk of different vascular events in the MRC/BHF Heart Protection Study. Circulation. 125: 2469-78. PMID 22539783 DOI: 10.1161/CIRCULATIONAHA.111.073684  0.378
2011 Otvos JD. The surprising AIM-HIGH results are not surprising when viewed through a particle lens. Journal of Clinical Lipidology. 5: 368-70. PMID 21981836 DOI: 10.1016/J.Jacl.2011.06.012  0.311
2011 Freedman BI, Langefeld CD, Murea M, Ma L, Otvos JD, Turner J, Antinozzi PA, Divers J, Hicks PJ, Bowden DW, Rocco MV, Parks JS. Apolipoprotein L1 nephropathy risk variants associate with HDL subfraction concentration in African Americans. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 26: 3805-10. PMID 21931123 DOI: 10.1093/Ndt/Gfr542  0.425
2011 Virani SS, Catellier DJ, Pompeii LA, Nambi V, Hoogeveen RC, Wasserman BA, Coresh J, Mosley TH, Otvos JD, Sharrett AR, Boerwinkle E, Ballantyne CM. Relation of cholesterol and lipoprotein parameters with carotid artery plaque characteristics: the Atherosclerosis Risk in Communities (ARIC) carotid MRI study. Atherosclerosis. 219: 596-602. PMID 21868017 DOI: 10.1016/J.Atherosclerosis.2011.08.001  0.491
2011 Baker JV, Neuhaus J, Duprez D, Cooper DA, Hoy J, Kuller L, Lampe FC, Liappis A, Friis-Moller N, Otvos J, Paton NI, Tracy R, Neaton JD. Inflammation predicts changes in high-density lipoprotein particles and apolipoprotein A1 following initiation of antiretroviral therapy. Aids (London, England). 25: 2133-42. PMID 21857489 DOI: 10.1097/Qad.0B013E32834Be088  0.431
2011 Paynter NP, Sesso HD, Conen D, Otvos JD, Mora S. Lipoprotein subclass abnormalities and incident hypertension in initially healthy women. Clinical Chemistry. 57: 1178-87. PMID 21700954 DOI: 10.1373/Clinchem.2011.167544  0.428
2011 Otvos JD, Mora S, Shalaurova I, Greenland P, Mackey RH, Goff DC. Clinical implications of discordance between low-density lipoprotein cholesterol and particle number. Journal of Clinical Lipidology. 5: 105-13. PMID 21392724 DOI: 10.1016/J.Jacl.2011.02.001  0.372
2011 Rosenson RS, Brewer HB, Chapman MJ, Fazio S, Hussain MM, Kontush A, Krauss RM, Otvos JD, Remaley AT, Schaefer EJ. HDL measures, particle heterogeneity, proposed nomenclature, and relation to atherosclerotic cardiovascular events. Clinical Chemistry. 57: 392-410. PMID 21266551 DOI: 10.1373/Clinchem.2010.155333  0.454
2011 Weiss R, Otvos JD, Sinnreich R, Miserez AR, Kark JD. The triglyceride to high-density lipoprotein-cholesterol ratio in adolescence and subsequent weight gain predict nuclear magnetic resonance-measured lipoprotein subclasses in adulthood. The Journal of Pediatrics. 158: 44-50. PMID 20801459 DOI: 10.1016/J.Jpeds.2010.07.002  0.445
2011 Duprez DA, Zhu N, Jacobs DR, Bahrami H, Lima J, Otvos J, Daniels LB, Maisel A. Incremental Predictive Value For Incident Cardiovascular Disease Of 4 Subclinical Markers Combined: Lipoprotein Particle Concentration, Nt-Probnp Concentration, Coronary Artery Calcification Score And Small Artery Stiffness In Asymptomatic Subjects In The Multi-Ethnic Study Of Atherosclerosis Journal of the American College of Cardiology. 57. DOI: 10.1016/S0735-1097(11)61228-X  0.368
2010 Lampe FC, Duprez DA, Kuller LH, Tracy R, Otvos J, Stroes E, Cooper DA, Hoy J, Paton NI, Friis-Møller N, Neuhaus J, Liappis AP, Phillips AN. Changes in lipids and lipoprotein particle concentrations after interruption of antiretroviral therapy. Journal of Acquired Immune Deficiency Syndromes (1999). 54: 275-84. PMID 20658749 DOI: 10.1097/Qai.0B013E3181D32158  0.474
2010 Mora S, Otvos JD, Rosenson RS, Pradhan A, Buring JE, Ridker PM. Lipoprotein particle size and concentration by nuclear magnetic resonance and incident type 2 diabetes in women. Diabetes. 59: 1153-60. PMID 20185808 DOI: 10.2337/Db09-1114  0.433
2010 Mora S, Otvos J, Ridker P. W26 Discordance Between Ldl Cholesterol And Ldl Particle Concentration In Relation To Incident Cvd Events In 27673 Women Atherosclerosis Supplements. 11: 6. DOI: 10.1016/S1567-5688(10)70027-1  0.446
2010 Virani SS, Catellier DJ, Nambi V, Hoogeveen RC, Wasserman BA, Coresh J, Mosley TH, Otvos JD, Sharrett AR, Boerwinkle E, Ballantyne CM. DISCORDANCE BETWEEN TRADITIONAL LIPID PARAMETERS, APOLIPOPROTEINS AND LIPOPROTEIN PARTICLE NUMBER: INSIGHTS FROM THE ATHEROSCLEROSIS RISK IN COMMUNITIES (ARIC) CAROTID MRI STUDY Journal of the American College of Cardiology. 55: A53.E501. DOI: 10.1016/S0735-1097(10)60502-5  0.419
2010 Orchard TJ, Robertson D, Bertolet M, Otvos J, Donner T, Ooi T, Pambianco G, Rana J, Smith D, Zoiopoulos L. INSULIN SENSITIZING THERAPY COMPARED TO INSULIN PROVIDING THERAPY FOR TYPE 2 DIABETES MELLITUS: EFFECTS ON LOW DENSITY LIPOPROTEIN PARTICLE CHARACTERISTICS BY NUCLEAR MAGNETIC RESONANCE LIPOPROFILE-III Journal of the American College of Cardiology. 55: A49.E462. DOI: 10.1016/S0735-1097(10)60463-9  0.36
2009 Howard WJ, Russell M, Fleg JL, Mete M, Ali T, Devereux RB, Galloway JM, Otvos JD, Ratner RE, Roman MJ, Silverman A, Umans JG, Weissman NJ, Wilson C, Howard BV. PREVENTION OF ATHEROSCLEROSIS WITH LDL-C LOWERING - LIPOPROTEIN CHANGES AND INTERACTIONS: THE SANDS STUDY. Journal of Clinical Lipidology. 3: 322-331. PMID 20161568 DOI: 10.1016/J.Jacl.2009.09.001  0.462
2009 Masulli M, Patti L, Riccardi G, Vaccaro O, Annuzzi G, Ebbesson SO, Fabsitz RR, Howard WJ, Otvos JD, Roman MJ, Wang H, Weissman NJ, Howard BV, Rivellese AA. Relation among lipoprotein subfractions and carotid atherosclerosis in Alaskan Eskimos (from the GOCADAN Study). The American Journal of Cardiology. 104: 1516-21. PMID 19932785 DOI: 10.1016/J.Amjcard.2009.07.021  0.512
2009 Duprez DA, Kuller LH, Tracy R, Otvos J, Cooper DA, Hoy J, Neuhaus J, Paton NI, Friis-Moller N, Lampe F, Liappis AP, Neaton JD. Lipoprotein particle subclasses, cardiovascular disease and HIV infection. Atherosclerosis. 207: 524-9. PMID 19515371 DOI: 10.1016/J.Atherosclerosis.2009.05.001  0.328
2009 Weiss R, Otvos JD, Flyvbjerg A, Miserez AR, Frystyk J, Sinnreich R, Kark JD. Adiponectin and lipoprotein particle size. Diabetes Care. 32: 1317-9. PMID 19389813 DOI: 10.2337/Dc09-0084  0.421
2009 Rosenson RS, Otvos JD, Hsia J. Effects of rosuvastatin and atorvastatin on LDL and HDL particle concentrations in patients with metabolic syndrome: a randomized, double-blind, controlled study. Diabetes Care. 32: 1087-91. PMID 19265025 DOI: 10.2337/Dc08-1681  0.458
2009 Mora S, Otvos JD, Rifai N, Rosenson RS, Buring JE, Ridker PM. Lipoprotein particle profiles by nuclear magnetic resonance compared with standard lipids and apolipoproteins in predicting incident cardiovascular disease in women. Circulation. 119: 931-9. PMID 19204302 DOI: 10.1161/Circulationaha.108.816181  0.456
2009 El Harchaoui K, Arsenault BJ, Franssen R, Després JP, Hovingh GK, Stroes ES, Otvos JD, Wareham NJ, Kastelein JJ, Khaw KT, Boekholdt SM. High-density lipoprotein particle size and concentration and coronary risk. Annals of Internal Medicine. 150: 84-93. PMID 19153411 DOI: 10.7326/0003-4819-150-2-200901200-00006  0.467
2009 Mora S, Buring JE, Ridker PM, Rifai N, Otvos JD, Rosenson RS. Response to Letter Regarding Article, “Lipoprotein Particle Profiles by Nuclear Magnetic Resonance Compared With Standard Lipids and Apolipoproteins in Predicting Incident Cardiovascular Disease in Women” Circulation. 120. DOI: 10.1161/Circulationaha.109.881219  0.436
2009 Kwiterovich P, Virgil D, Khouzami V, Otvos J. Abstract: P357 QUANTITATIVE EXPRESSION OF THE LARGEST SUBCLASS OF HDL (H5C), VLDLTG AND SMALL LDL PARTICLES (SLDLP) IN INFANTS AND THEIR PARENTS Atherosclerosis Supplements. 10. DOI: 10.1016/S1567-5688(09)70652-X  0.349
2008 Otvos JD, Rudel LL, McConnell JP. Concerns regarding lipoprotein particle measurement by ion mobility analysis. Clinical Chemistry. 54: 2086-7; author reply. PMID 19042998 DOI: 10.1373/Clinchem.2008.113795  0.451
2008 Hsia J, Otvos JD, Rossouw JE, Wu L, Wassertheil-Smoller S, Hendrix SL, Robinson JG, Lund B, Kuller LH. Lipoprotein particle concentrations may explain the absence of coronary protection in the women's health initiative hormone trials. Arteriosclerosis, Thrombosis, and Vascular Biology. 28: 1666-71. PMID 18599797 DOI: 10.1161/Atvbaha.108.170431  0.448
2008 van der Graaf A, Rodenburg J, Vissers MN, Hutten BA, Wiegman A, Trip MD, Stroes ES, Wijburg FA, Otvos JD, Kastelein JJ. Atherogenic lipoprotein particle size and concentrations and the effect of pravastatin in children with familial hypercholesterolemia. The Journal of Pediatrics. 152: 873-8. PMID 18492534 DOI: 10.1016/J.Jpeds.2007.11.043  0.339
2007 Cromwell WC, Otvos JD, Keyes MJ, Pencina MJ, Sullivan L, Vasan RS, Wilson PW, D'Agostino RB. LDL Particle Number and Risk of Future Cardiovascular Disease in the Framingham Offspring Study - Implications for LDL Management. Journal of Clinical Lipidology. 1: 583-92. PMID 19657464 DOI: 10.1016/J.Jacl.2007.10.001  0.509
2007 Birjmohun RS, Dallinga-Thie GM, Kuivenhoven JA, Stroes ES, Otvos JD, Wareham NJ, Luben R, Kastelein JJ, Khaw KT, Boekholdt SM. Apolipoprotein A-II is inversely associated with risk of future coronary artery disease. Circulation. 116: 2029-35. PMID 17923573 DOI: 10.1161/Circulationaha.107.704031  0.372
2007 El Harchaoui K, van der Steeg WA, Stroes ES, Kuivenhoven JA, Otvos JD, Wareham NJ, Hutten BA, Kastelein JJ, Khaw KT, Boekholdt SM. Value of low-density lipoprotein particle number and size as predictors of coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study. Journal of the American College of Cardiology. 49: 547-53. PMID 17276177 DOI: 10.1016/J.Jacc.2006.09.043  0.495
2007 Singh U, Otvos J, Dasgupta A, Lemos JAd, Devaraj S, Jialal I. High-dose α-tocopherol therapy does not affect HDL subfractions in patients with coronary artery disease on statin therapy Clinical Chemistry. 53: 525-528. PMID 17234730 DOI: 10.1373/Clinchem.2006.078865  0.438
2007 Mora S, Szklo M, Otvos JD, Greenland P, Psaty BM, Goff DC, O'Leary DH, Saad MF, Tsai MY, Sharrett AR. LDL particle subclasses, LDL particle size, and carotid atherosclerosis in the Multi-Ethnic Study of Atherosclerosis (MESA). Atherosclerosis. 192: 211-7. PMID 16765964 DOI: 10.1016/J.Atherosclerosis.2006.05.007  0.461
2007 Steeg WAvd, Holme I, Boekholdt SM, Otvos JD, Stroes ES, Wareham NJ, Kastelein JJ, Khaw KT. Lb-Or-3 Relationship Between High-Density Lipoprotein Particle Size And Coronary Artery Disease Risk In The Epic-Norfolk Prospective Study Atherosclerosis Supplements. 8: 227. DOI: 10.1016/S1567-5688(07)71862-7  0.417
2006 Cromwell WC, Otvos JD. Heterogeneity of low-density lipoprotein particle number in patients with type 2 diabetes mellitus and low-density lipoprotein cholesterol <100 mg/dl. The American Journal of Cardiology. 98: 1599-602. PMID 17145217 DOI: 10.1016/J.Amjcard.2006.07.036  0.469
2006 Jeyarajah EJ, Cromwell WC, Otvos JD. Lipoprotein particle analysis by nuclear magnetic resonance spectroscopy. Clinics in Laboratory Medicine. 26: 847-70. PMID 17110242 DOI: 10.1016/J.Cll.2006.07.006  0.502
2006 Lyons TJ, Jenkins AJ, Zheng D, Klein RL, Otvos JD, Yu Y, Lackland DT, McGee D, McHenry MB, Lopes-Virella M, Garvey WT. Nuclear magnetic resonance-determined lipoprotein subclass profile in the DCCT/EDIC cohort: associations with carotid intima-media thickness. Diabetic Medicine : a Journal of the British Diabetic Association. 23: 955-66. PMID 16922701 DOI: 10.1111/J.1464-5491.2006.01905.X  0.374
2006 Seip RL, Otvos J, Bilbie C, Tsongalis GJ, Miles M, Zoeller R, Visich P, Gordon P, Angelopoulos TJ, Pescatello L, Moyna N, Thompson PD. The effect of apolipoprotein E genotype on serum lipoprotein particle response to exercise. Atherosclerosis. 188: 126-33. PMID 16842800 DOI: 10.1016/J.Atherosclerosis.2005.06.050  0.361
2006 Otvos JD, Collins D, Freedman DS, Shalaurova I, Schaefer EJ, McNamara JR, Bloomfield HE, Robins SJ. Low-density lipoprotein and high-density lipoprotein particle subclasses predict coronary events and are favorably changed by gemfibrozil therapy in the Veterans Affairs High-Density Lipoprotein Intervention Trial. Circulation. 113: 1556-63. PMID 16534013 DOI: 10.1161/Circulationaha.105.565135  0.461
2006 Kathiresan S, Otvos JD, Sullivan LM, Keyes MJ, Schaefer EJ, Wilson PW, D'Agostino RB, Vasan RS, Robins SJ. Increased small low-density lipoprotein particle number: a prominent feature of the metabolic syndrome in the Framingham Heart Study. Circulation. 113: 20-9. PMID 16380547 DOI: 10.1161/Circulationaha.105.567107  0.478
2006 Shadid S, LaForge R, Otvos JD, Jensen MD. Treatment of obesity with diet/exercise versus pioglitazone has distinct effects on lipoprotein particle size. Atherosclerosis. 188: 370-6. PMID 16313908 DOI: 10.1016/J.Atherosclerosis.2005.10.038  0.347
2006 Yishak AA, Costacou T, Virella G, Zgibor J, Fried L, Walsh M, Evans RW, Lopes-Virella M, Kagan VE, Otvos J, Orchard TJ. Novel predictors of overt nephropathy in subjects with type 1 diabetes. A nested case control study from the Pittsburgh Epidemiology of Diabetes Complications cohort. Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association - European Renal Association. 21: 93-100. PMID 16144851 DOI: 10.1093/Ndt/Gfi103  0.378
2006 Ruaño G, Seip RL, Windemuth A, Zöllner S, Tsongalis GJ, Ordovas J, Otvos J, Bilbie C, Miles M, Zoeller R, Visich P, Gordon P, Angelopoulos TJ, Pescatello L, Moyna N, et al. Apolipoprotein A1 genotype affects the change in high density lipoprotein cholesterol subfractions with exercise training. Atherosclerosis. 185: 65-9. PMID 16005460 DOI: 10.1016/J.Atherosclerosis.2005.05.029  0.397
2006 Elharchaoui K, Steeg WAVD, Boekholdt SM, Stroes ESG, Otvos JD, Kuivenhoven JA, Bingham SA, Day NE, Khaw KT, Kastelein JJP. Mo-P1:109 LDL particle number and risk for future cardiovascular risk Atherosclerosis Supplements. 7: 70. DOI: 10.1016/S1567-5688(06)80244-8  0.377
2005 Festa A, Williams K, Hanley AJ, Otvos JD, Goff DC, Wagenknecht LE, Haffner SM. Nuclear magnetic resonance lipoprotein abnormalities in prediabetic subjects in the Insulin Resistance Atherosclerosis Study. Circulation. 111: 3465-72. PMID 15983261 DOI: 10.1161/Circulationaha.104.512079  0.41
2005 Kwiterovich PO, Cockrill SL, Virgil DG, Garrett ES, Otvos J, Knight-Gibson C, Alaupovic P, Forte T, Zhang L, Farwig ZN, Macfarlane RD. A large high-density lipoprotein enriched in apolipoprotein C-I: a novel biochemical marker in infants of lower birth weight and younger gestational age. Jama. 293: 1891-9. PMID 15840864 DOI: 10.1001/Jama.293.15.1891  0.404
2005 Suter PM, Marmier G, Veya-Linder C, Hänseler E, Lentz J, Vetter W, Otvos J. Effect of orlistat on postprandial lipemia, NMR lipoprotein subclass profiles and particle size Atherosclerosis. 180: 127-135. PMID 15823285 DOI: 10.1016/J.Atherosclerosis.2004.11.023  0.416
2005 Goff DC, D'Agostino RB, Haffner SM, Otvos JD. Insulin resistance and adiposity influence lipoprotein size and subclass concentrations. Results from the Insulin Resistance Atherosclerosis Study. Metabolism: Clinical and Experimental. 54: 264-70. PMID 15690322 DOI: 10.1016/J.Metabol.2004.09.002  0.414
2005 Ma K, Forte T, Otvos JD, Chan L. Differential additive effects of endothelial lipase and scavenger receptor-class B type I on high-density lipoprotein metabolism in knockout mouse models. Arteriosclerosis, Thrombosis, and Vascular Biology. 25: 149-54. PMID 15539616 DOI: 10.1161/01.Atv.0000150414.89591.6A  0.345
2004 Cromwell WC, Otvos JD. Low-density lipoprotein particle number and risk for cardiovascular disease. Current Atherosclerosis Reports. 6: 381-7. PMID 15296705 DOI: 10.1007/S11883-004-0050-5  0.512
2004 Tsai MY, Georgopoulos A, Otvos JD, Ordovas JM, Hanson NQ, Peacock JM, Arnett DK. Comparison of ultracentrifugation and nuclear magnetic resonance spectroscopy in the quantification of triglyceride-rich lipoproteins after an oral fat load. Clinical Chemistry. 50: 1201-4. PMID 15142979 DOI: 10.1373/Clinchem.2004.032938  0.453
2004 Freedman DS, Otvos JD, Jeyarajah EJ, Shalaurova I, Cupples LA, Parise H, D'Agostino RB, Wilson PW, Schaefer EJ. Sex and age differences in lipoprotein subclasses measured by nuclear magnetic resonance spectroscopy: the Framingham Study. Clinical Chemistry. 50: 1189-200. PMID 15107310 DOI: 10.1373/Clinchem.2004.032763  0.438
2004 Kuivenhoven JA, Hovingh GK, van Tol A, Jauhiainen M, Ehnholm C, Fruchart JC, Brinton EA, Otvos JD, Smelt AH, Brownlee A, Zwinderman AH, Hayden MR, Kastelein JJ. Heterozygosity for ABCA1 gene mutations: effects on enzymes, apolipoproteins and lipoprotein particle size. Atherosclerosis. 171: 311-9. PMID 14644402 DOI: 10.1016/J.Atherosclerosis.2003.08.014  0.429
2003 Li Z, Otvos JD, Lamon-Fava S, Carrasco WV, Lichtenstein AH, McNamara JR, Ordovas JM, Schaefer EJ. Men and women differ in lipoprotein response to dietary saturated fat and cholesterol restriction. The Journal of Nutrition. 133: 3428-33. PMID 14608054 DOI: 10.1093/Jn/133.11.3428  0.399
2003 Jenkins AJ, Lyons TJ, Zheng D, Otvos JD, Lackland DT, McGee D, Garvey WT, Klein RL. Lipoproteins in the DCCT/EDIC cohort: associations with diabetic nephropathy. Kidney International. 64: 817-28. PMID 12911531 DOI: 10.1046/J.1523-1755.2003.00164.X  0.472
2003 Jenkins AJ, Lyons TJ, Zheng D, Otvos JD, Lackland DT, McGee D, Garvey WT, Klein RL. Serum lipoproteins in the diabetes control and complications trial/epidemiology of diabetes intervention and complications cohort: associations with gender and glycemia. Diabetes Care. 26: 810-8. PMID 12610042 DOI: 10.2337/Diacare.26.3.810  0.385
2003 Ma K, Cilingiroglu M, Otvos JD, Ballantyne CM, Marian AJ, Chan L. Endothelial lipase is a major genetic determinant for high-density lipoprotein concentration, structure, and metabolism. Proceedings of the National Academy of Sciences of the United States of America. 100: 2748-53. PMID 12601178 DOI: 10.1073/Pnas.0438039100  0.442
2002 Colhoun HM, Taskinen MR, Otvos JD, Van Den Berg P, O'Connor J, Van Tol A. Relationship of phospholipid transfer protein activity to HDL and apolipoprotein B-containing lipoproteins in subjects with and without type 1 diabetes. Diabetes. 51: 3300-5. PMID 12401722 DOI: 10.2337/Diabetes.51.11.3300  0.435
2002 Blake GJ, Otvos JD, Rifai N, Ridker PM. Low-density lipoprotein particle concentration and size as determined by nuclear magnetic resonance spectroscopy as predictors of cardiovascular disease in women. Circulation. 106: 1930-7. PMID 12370215 DOI: 10.1161/01.Cir.0000033222.75187.B9  0.435
2002 Kuller L, Arnold A, Tracy R, Otvos J, Burke G, Psaty B, Siscovick D, Freedman DS, Kronmal R. Nuclear magnetic resonance spectroscopy of lipoproteins and risk of coronary heart disease in the cardiovascular health study. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1175-80. PMID 12117734 DOI: 10.1161/01.Atv.0000022015.97341.3A  0.369
2002 Brousseau ME, O'Connor JJ, Ordovas JM, Collins D, Otvos JD, Massov T, McNamara JR, Rubins HB, Robins SJ, Schaefer EJ. Cholesteryl ester transfer protein TaqI B2B2 genotype is associated with higher HDL cholesterol levels and lower risk of coronary heart disease end points in men with HDL deficiency: Veterans Affairs HDL Cholesterol Intervention Trial. Arteriosclerosis, Thrombosis, and Vascular Biology. 22: 1148-54. PMID 12117730 DOI: 10.1161/01.Atv.0000024566.57589.2E  0.457
2002 Rosenson RS, Otvos JD, Freedman DS. Relations of lipoprotein subclass levels and low-density lipoprotein size to progression of coronary artery disease in the Pravastatin Limitation of Atherosclerosis in the Coronary Arteries (PLAC-I) trial. The American Journal of Cardiology. 90: 89-94. PMID 12106834 DOI: 10.1016/S0002-9149(02)02427-X  0.456
2002 Colhoun HM, Otvos JD, Rubens MB, Taskinen MR, Underwood SR, Fuller JH. Lipoprotein subclasses and particle sizes and their relationship with coronary artery calcification in men and women with and without type 1 diabetes. Diabetes. 51: 1949-56. PMID 12031985 DOI: 10.2337/Diabetes.51.6.1949  0.428
2002 Otvos JD, Shalaurova I, Freedman DS, Rosenson RS. Effects of pravastatin treatment on lipoprotein subclass profiles and particle size in the PLAC-I trial. Atherosclerosis. 160: 41-8. PMID 11755921 DOI: 10.1016/S0021-9150(01)00544-5  0.496
2001 Galluzzi JR, Cupples LA, Otvos JD, Wilson PWF, Schaefer EJ, Ordovas JM. Association of the A/T54 polymorphism in the intestinal fatty acid binding protein with variations in plasma lipids in the Framingham Offspring Study. Atherosclerosis. 159: 417-424. PMID 11730822 DOI: 10.1016/S0021-9150(01)00517-2  0.35
2001 Russo GT, Meigs JB, Cupples LA, Demissie S, Otvos JD, Wilson PWF, Lahoz C, Cucinotta D, Couture P, Mallory T, Schaefer EJ, Ordovas JM. Association of the Sst-I polymorphism at the APOC3 gene locus with variations in lipid levels, lipoprotein subclass profiles and coronary heart disease risk: the Framingham offspring study. Atherosclerosis. 158: 173-181. PMID 11500189 DOI: 10.1016/S0021-9150(01)00409-9  0.415
2001 Tangney CC, Mosca LJ, Otvos JD, Rosenson RS. Oral 17β-estradiol and medroxyprogesterone acetate therapy in postmenopausal women increases HDL particle size Atherosclerosis. 155: 425-430. PMID 11254913 DOI: 10.1016/S0021-9150(00)00577-3  0.434
2001 Freedman DS, Bowman BA, Srinivasan SR, Berenson GS, Otvos JD. Distribution and correlates of high-density lipoprotein subclasses among children and adolescents. Metabolism-Clinical and Experimental. 50: 370-376. PMID 11230794 DOI: 10.1053/Meta.2001.21027  0.476
2001 Miller M, Dolinar C, Cromwell W, Otvos JD. Effectiveness of high doses of simvastatin as monotherapy in mixed hyperlipidemia. American Journal of Cardiology. 87: 232-234. PMID 11152850 DOI: 10.1016/S0002-9149(00)01327-8  0.423
2000 Freedman DS, Bowman BA, Otvos JD, Srinivasan SR, Berenson GS. Levels and correlates of LDL and VLDL particle sizes among children: the Bogalusa heart study Atherosclerosis. 152: 441-449. PMID 10998473 DOI: 10.1016/S0021-9150(99)00495-5  0.447
2000 Isasi CR, Shea S, Deckelbaum RJ, Couch SC, Starc TJ, Otvos JD, Berglund L. Apolipoprotein ε2 allele is associated with an anti-atherogenic lipoprotein profile in children: The Columbia University biomarkers study Pediatrics. 106: 568-575. PMID 10969104 DOI: 10.1542/Peds.106.3.568  0.395
2000 Ordovas JM, Cupples LA, Corella D, Otvos JD, Osgood D, Martinez A, Lahoz C, Coltell O, Wilson PWF, Schaefer EJ. Association of Cholesteryl Ester Transfer Protein–TaqIB Polymorphism With Variations in Lipoprotein Subclasses and Coronary Heart Disease Risk : The Framingham Study Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 1323-1329. PMID 10807749 DOI: 10.1161/01.Atv.20.5.1323  0.465
2000 Couture P, Otvos JD, Cupples LA, Lahoz C, Wilson PWF, Schaefer EJ, Ordovas JM. Association of the C−514T Polymorphism in the Hepatic Lipase Gene With Variations in Lipoprotein Subclass Profiles The Framingham Offspring Study Arteriosclerosis, Thrombosis, and Vascular Biology. 20: 815-822. PMID 10712408 DOI: 10.1161/01.Atv.20.3.815  0.438
2000 Couture P, Otvos JD, Cupples LA, Wilson PWF, Schaefer EJ, Ordovas JM. Absence of association between genetic variation in the promoter of the microsomal triglyceride transfer protein gene and plasma lipoproteins in the Framingham Offspring Study. Atherosclerosis. 148: 337-343. PMID 10657570 DOI: 10.1016/S0021-9150(99)00281-6  0.464
2000 Rosenson R, Shalaurova I, Otvos J. Relations of lipoprotein subclass levels and LDL size to reduction in coronary atherosclerosis in the PLAC I trial Atherosclerosis. 151: 237. DOI: 10.1016/S0021-9150(00)81073-4  0.385
2000 Otvos J, Jeyarajah E, Ordovas J, McNamara J, Schaefer E, Wilson P. Lipoprotein subclasses measured by NMR spectroscopy help explain the sex differential in coronary artery disease: Results from the Framingham Offspring Study Atherosclerosis. 151: 128. DOI: 10.1016/S0021-9150(00)80578-X  0.337
2000 Otvos J, Cromwell W, Alexander C, Landsman P, Kush D, Mercuri M. Effects of simvastatin and atorvastatin on total and fractionated HDL cholesterol Atherosclerosis. 151: 48. DOI: 10.1016/S0021-9150(00)80217-8  0.432
2000 Colhoun HM, Scheek LM, Otvos J, Fuller JH, Tol AV. Cholesteryl ester transfer is associated with HDL size and coronary artery calcification in type 1 diabetic and non-diabetic subjects Atherosclerosis. 151: 14. DOI: 10.1016/S0021-9150(00)80061-1  0.321
1999 Yu HH, Ginsburg GS, O'Toole ML, Otvos JD, Douglas PS, Rifai N. Acute changes in serum lipids and lipoprotein subclasses in triathletes as assessed by proton nuclear magnetic resonance spectroscopy. Arteriosclerosis, Thrombosis, and Vascular Biology. 19: 1945-9. PMID 10446075 DOI: 10.1161/01.Atv.19.8.1945  0.494
1999 Otvos J. Measurement of triglyceride-rich lipoproteins by nuclear magnetic resonance spectroscopy. Clinical Cardiology. 22. PMID 10376193 DOI: 10.1002/Clc.4960221405  0.502
1998 Vadlamudi S, MacLean P, Israel RG, Marks RH, Hickey M, Otvos J, Barakat H. Effects of oral combined hormone replacement therapy on plasma lipids and lipoproteins. Metabolism: Clinical and Experimental. 47: 1222-6. PMID 9781625 DOI: 10.1016/S0026-0495(98)90327-4  0.472
1998 Freedman DS, Otvos JD, Jeyarajah EJ, Barboriak JJ, Anderson AJ, Walker JA. Relation of lipoprotein subclasses as measured by proton nuclear magnetic resonance spectroscopy to coronary artery disease. Arteriosclerosis, Thrombosis, and Vascular Biology. 18: 1046-53. PMID 9672064 DOI: 10.1161/01.Atv.18.7.1046  0.515
1998 Giri S, Thompson PD, Taxel P, Contois JH, Otvos J, Allen R, Ens G, Wu AH, Waters DD. Oral estrogen improves serum lipids, homocysteine and fibrinolysis in elderly men. Atherosclerosis. 137: 359-66. PMID 9622279 DOI: 10.1016/S0021-9150(98)00022-7  0.453
1998 Giri S, Thompson PD, Contois JH, Taxel P, Otvos J, Allen R, Ens G, Wu AHB, Waters DD. Low-dose estrogen improves serum lipids, homocysteine, and fibrinolysis without altering markers of hemostasis in elderly men Journal of the American College of Cardiology. 31: 194-195. DOI: 10.1016/S0735-1097(98)81485-X  0.354
1997 Parsons SK, Skapek SX, Neufeld EJ, Kuhlman C, Young ML, Donnelly M, Brunzell JD, Otvos JD, Sallan SE, Rifai N. Asparaginase-associated lipid abnormalities in children with acute lymphoblastic leukemia. Blood. 89: 1886-1895. DOI: 10.1182/Blood.V89.6.1886  0.413
1992 Otvos JD, Jeyarajah EJ, Bennett DW, Krauss RM. Development of a proton nuclear magnetic resonance spectroscopic method for determining plasma lipoprotein concentrations and subspecies distributions from a single, rapid measurement. Clinical Chemistry. 38: 1632-1638. DOI: 10.1093/Clinchem/38.9.1632  0.417
Low-probability matches (unlikely to be authored by this person)
2017 Connelly MA, Otvos JD, Shalaurova I, Playford MP, Mehta NN. GlycA, a novel biomarker of systemic inflammation and cardiovascular disease risk. Journal of Translational Medicine. 15: 219. PMID 29078787 DOI: 10.1186/S12967-017-1321-6  0.299
2018 Tibuakuu M, Fashanu OE, Zhao D, Otvos JD, Brown TT, Haberlen SA, Guallar E, Budoff MJ, Palella FJ, Martinson JJ, Akinkuolie AO, Mora S, Post WS, Michos ED. GlycA, a novel inflammatory marker, is associated with subclinical coronary disease in the multicenter AIDS cohort study. Aids (London, England). PMID 30475263 DOI: 10.1097/Qad.0000000000002079  0.296
2016 Jago R, Drews KL, Otvos JD, Willi SM, Buse JB. Novel measures of inflammation and insulin resistance are related to obesity and fitness in a diverse sample of 11-14 year olds: The HEALTHY Study. International Journal of Obesity (2005). 40: 1157-63. PMID 27143035 DOI: 10.1038/Ijo.2016.84  0.295
2002 Slentz CA, Houmard JA, Duscha BD, Knetzger KJ, Wharton MB, Bales CB, Henes SC, Kelly LS, Samsa GP, Otvos J, Kraus WE. EFFECT OF EXERCISE TRAINING DOSE AND INTENSITY ON LIPOPROTEINS AND LIPOPROTEIN SUBFRACTIONS Medicine & Science in Sports & Exercise. 34: S50. DOI: 10.1097/00005768-200205001-00275  0.294
2023 Deets A, Joshi PH, Chandra A, Singh K, Khera A, Virani SS, Ballantyne CM, Otvos JD, Dullaart RPF, Gruppen EG, Connelly MA, Ayers C, Navar AM, Pandey A, Wilkins JT, et al. Novel Size-Based High-Density Lipoprotein Subspecies and Incident Vascular Events. Journal of the American Heart Association. 12: e031160. PMID 37929707 DOI: 10.1161/JAHA.123.031160  0.293
2020 Jang S, Ogunmoroti O, Ndumele CE, Zhao D, Rao VN, Fashanu OE, Tibuakuu M, Otvos JD, Benson EM, Ouyang P, Michos ED. Association of the Novel Inflammatory Marker GlycA and Incident Heart Failure and Its Subtypes of Preserved and Reduced Ejection Fraction: The Multi-Ethnic Study of Atherosclerosis. Circulation. Heart Failure. CIRCHEARTFAILURE1200. PMID 32762458 DOI: 10.1161/Circheartfailure.120.007067  0.292
2007 Cali AM, Zern TL, Taksali SE, de Oliveira AM, Dufour S, Otvos JD, Caprio S. Intrahepatic fat accumulation and alterations in lipoprotein composition in obese adolescents: a perfect proatherogenic state. Diabetes Care. 30: 3093-8. PMID 17717283 DOI: 10.2337/Dc07-1088  0.291
2015 Kempen H, Asztalos BF, Jeyarajah E, Otvos J, Gomaraschi M, Calabresi L, Kallend D, Bobillier A, Bellibas S, Wijngaard P. Acute and prolonged changes in lipoprotein profile in human volunteers treated with single ascending doses of MDCO-216 (apoA1-MILANO/POPC) Atherosclerosis. 241. DOI: 10.1016/J.Atherosclerosis.2015.04.234  0.289
2016 Connelly MA, Gruppen EG, Wolak-Dinsmore J, Matyus SP, Riphagen IJ, Shalaurova I, Bakker SJ, Otvos JD, Dullaart RP. GlycA, a marker of acute phase glycoproteins, and the risk of incident type 2 diabetes mellitus: PREVEND study. Clinica Chimica Acta; International Journal of Clinical Chemistry. 452: 10-7. PMID 26549655 DOI: 10.1016/J.Cca.2015.11.001  0.286
2004 Li Z, Lamon-Fava S, Otvos J, Lichtenstein AH, Velez-Carrasco W, McNamara JR, Ordovas JM, Schaefer EJ. Fish consumption shifts lipoprotein subfractions to a less atherogenic pattern in humans. The Journal of Nutrition. 134: 1724-8. PMID 15226460 DOI: 10.1093/Jn/134.7.1724  0.285
2022 Bortnick AE, Buzkova P, Otvos J, Jensen M, Tsai MY, Budoff M, Mackey R, El Khoudary SR, Favari E, Kim RS, Rodriguez CJ, Thanassoulis G, Kizer JR. High-Density Lipoprotein and Long-Term Incidence and Progression of Aortic Valve Calcification: The Multi-Ethnic Study of Atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology. 101161ATVBAHA1223180. PMID 35979837 DOI: 10.1161/ATVBAHA.122.318004  0.283
2018 Taylor PC, Kremer JM, Emery P, Zuckerman SH, Ruotolo G, Zhong J, Chen L, Witt S, Saifan C, Kurzawa M, Otvos JD, Connelly MA, Macias WL, Schlichting DE, Rooney TP, et al. Lipid profile and effect of statin treatment in pooled phase II and phase III baricitinib studies. Annals of the Rheumatic Diseases. PMID 29463520 DOI: 10.1136/Annrheumdis-2017-212461  0.282
2020 Ross LM, Slentz CA, Shalaurova I, Connelly MA, Otvos JD, Bales CW, Houmard JA, Kraus WE. Abstract P177: Effects of Gender, Race, and Glucose Tolerance on Lipoprotein Insulin Resistance Index Responses to Exercise Training Circulation. 141. DOI: 10.1161/Circ.141.Suppl_1.P177  0.281
2016 Duprez DA, Otvos J, Sanchez OA, Mackey RH, Tracy R, Jacobs DR. Comparison of the Predictive Value of GlycA and Other Biomarkers of Inflammation for Total Death, Incident Cardiovascular Events, Noncardiovascular and Noncancer Inflammatory-Related Events, and Total Cancer Events. Clinical Chemistry. PMID 27173011 DOI: 10.1373/Clinchem.2016.255828  0.28
2020 Osté MCJ, Flores-Guerrero JL, Gruppen EG, Kieneker LM, Connelly MA, Otvos JD, Dullaart RPF, Bakker SJL. High Plasma Branched-Chain Amino Acids Are Associated with Higher Risk of Post-Transplant Diabetes Mellitus in Renal Transplant Recipients. Journal of Clinical Medicine. 9: 511. PMID 32069900 DOI: 10.3390/Jcm9020511  0.279
2015 Chung CP, Ormseth MJ, Connelly MA, Oeser A, Solus JF, Otvos JD, Raggi P, Stein CM. GlycA, a novel marker of inflammation, is elevated in systemic lupus erythematosus. Lupus. PMID 26637290 DOI: 10.1177/0961203315617842  0.275
2017 Connelly MA, Otvos JD, Zhang Q, Zhang S, Antalis CJ, Chang AM, Hoogwerf BJ. Effects of hepato-preferential basal insulin peglispro on nuclear magnetic resonance biomarkers lipoprotein insulin resistance index and GlycA in patients with diabetes. Biomarkers in Medicine. 11: 991-1001. PMID 29160108 DOI: 10.2217/Bmm-2017-0112  0.275
2016 Chandler PD, Akinkuolie AO, Tobias DK, Lawler PR, Li C, Moorthy MV, Wang L, Duprez DA, Jacobs DR, Glynn RJ, Otvos J, Connelly MA, Post WS, Ridker PM, Manson JE, et al. Association of N-Linked Glycoprotein Acetyls and Colorectal Cancer Incidence and Mortality. Plos One. 11: e0165615. PMID 27902713 DOI: 10.1371/Journal.Pone.0165615  0.273
2017 Kianoush S, Bittencourt M, Lotufo P, Bensenor I, Jones SR, DeFilippis AP, Toth P, Otvos JD, Tibuakuu M, Hall ME, Harada PHN, Blaha MJ. Association Between Smoking and Serum GlycA and High-Sensitivity C-Reactive Protein Levels: The Multi-Ethnic Study of Atherosclerosis (MESA) and Brazilian Longitudinal Study of Adult Health (ELSA-Brasil). Journal of the American Heart Association. 6. PMID 28838917 DOI: 10.1161/Jaha.117.006545  0.271
2022 Karwatowska-Prokopczuk E, Tardif JC, Gaudet D, Ballantyne CM, Shapiro MD, Moriarty PM, Baum SJ, Amour ES, Alexander VJ, Xia S, Otvos JD, Witztum JL, Tsimikas S. Effect of olezarsen targeting APOC-III on lipoprotein size and particle number measured by NMR in patients with hypertriglyceridemia. Journal of Clinical Lipidology. PMID 35902351 DOI: 10.1016/j.jacl.2022.06.005  0.268
2021 Sampson M, Ballout RA, Soffer D, Wolska A, Wilson S, Meeusen J, Donato LJ, Fatica E, Otvos JD, Brinton EA, Rosenson RS, Wilson P, Amar M, Shamburek R, Karathanasis SK, et al. A new phenotypic classification system for dyslipidemias based on the standard lipid panel. Lipids in Health and Disease. 20: 170. PMID 34838008 DOI: 10.1186/s12944-021-01585-8  0.268
2019 Delatour V, Clouet-Foraison N, Gaie-Levrel N, Marcovina S, Hoofnagle A, Kuklenyik Z, Caulfield M, Otvos J, Contois J, Krauss R, Kulkarni K, Remaley A, Vesper H, Cobbaert C, Gillery P. Standardization of advanced lipoprotein testing: The BioSITrace project Clinica Chimica Acta. 493. DOI: 10.1016/J.Cca.2019.03.1479  0.266
2016 Chandler PD, Akinkuolie A, Tobias D, Wang L, Moorthy MV, Ridker PM, Lee I, Manson JE, Buring JE, Otvos J, Mora S. Abstract B79: Novel protein glycan biomarker and future colorectal cancer Molecular Cancer Research. 14. DOI: 10.1158/1557-3125.Metca15-B79  0.264
2021 Hu K, Camila Perez-Matos M, Argemi J, Vilar E, Shalaurova I, Bullitt E, Landeen L, Sugahara G, Deng H, Mathur K, Tran S, Cai H, He H, Yalcin Y, Vieira Barbosa J, ... ... Otvos JD, et al. Lipoprotein Z, A novel hepatotoxic lipoprotein, predicts outcome in alcoholic hepatitis. Hepatology (Baltimore, Md.). PMID 34662439 DOI: 10.1002/hep.32203  0.261
2004 Kwiterovich PO, Virgil DG, Garrett ES, Otvos J, Driggers R, Blakemore K, Cockrill SL, Macfarlane RD. Lipoprotein heterogeneity at birth: influence of gestational age and race on lipoprotein subclasses and Lp (a) lipoprotein. Ethnicity & Disease. 14: 351-9. PMID 15328936  0.259
2015 Bartlett DB, Connelly MA, AbouAssi H, Bateman LA, Tune KN, Huebner JL, Kraus VB, Winegar DA, Otvos JD, Kraus WE, Huffman KM. A novel inflammatory biomarker, GlycA, associates with disease activity in rheumatoid arthritis and cardio-metabolic risk in BMI-matched controls. Arthritis Research & Therapy. 18: 86. PMID 27067270 DOI: 10.1186/S13075-016-0982-5  0.258
2012 Le N, Jin R, Tershakovec AM, Neff DR, Tomassini JE, Otvos J, Wilson P. Changes in Lipoprotein Particle Number with Ezetimibe/Simvastatin Co-administered with Extended-Release Niacin in Patients with Type II Hyperlipidemia† Journal of Clinical Lipidology. 6: 254-255. DOI: 10.1016/J.Jacl.2012.04.012  0.257
2023 Elliott PS, Harrington JM, Millar SR, Otvos JD, Perry IJ, Phillips CM. Plant-based diet indices and lipoprotein particle subclass profiles: A cross-sectional analysis of middle- to older-aged adults. Atherosclerosis. 380: 117190. PMID 37552902 DOI: 10.1016/j.atherosclerosis.2023.117190  0.255
2023 Cole J, Otvos JD, Remaley AT. A Translational Tool to Facilitate Use of Apolipoprotein B for Clinical Decision-Making. Clinical Chemistry. 69: 41-47. PMID 36366949 DOI: 10.1093/clinchem/hvac161  0.254
2020 Ross LM, Slentz CA, Shalaurova IY, Otvos JD, Connelly MA, Bales CW, Houmard JA, Kraus WE. 169-OR: Differential Effects of Amount, Intensity, and Mode of Exercise Training on the Diabetes Risk Index Diabetes. 69. DOI: 10.2337/Db20-169-Or  0.254
2017 Gruppen EG, Garcia E, Connelly MA, Jeyarajah EJ, Otvos JD, Bakker SJL, Dullaart RPF. TMAO is Associated with Mortality: Impact of Modestly Impaired Renal Function. Scientific Reports. 7: 13781. PMID 29061990 DOI: 10.1038/S41598-017-13739-9  0.253
1980 Otvos JD, Browne DT. Characterization of the histidine residues in alkaline phosphatase by carbon-13 nuclear magnetic resonance. Biochemistry. 19: 4011-21. PMID 6996713 DOI: 10.1021/Bi00558A019  0.253
2019 Ross LM, Slentz CA, Shalaurova I, Connelly MA, Otvos JD, Bales CW, Houmard JA, Kraus WE. The Differential Effects Of Amount, Intensity, And Mode Of Exercise Training On A Novel Lipoprotein Multimarker Of Insulin Resistance Medicine & Science in Sports & Exercise. 51: 175-176. DOI: 10.1249/01.Mss.0000561029.25645.78  0.252
2019 Flores-Guerrero JL, Groothof D, Connelly MA, Otvos JD, Bakker SJL, Dullaart RPF. Concentration of Branched-Chain Amino Acids Is a Strong Risk Marker for Incident Hypertension. Hypertension. 74: 1428-1435. PMID 31587574 DOI: 10.1161/Hypertensionaha.119.13735  0.252
2020 Meyers A, Cravalho CK, Villalobos-Perez A, Matta S, Mabundo L, Courville AB, Sampson ML, Otvos JD, Chung ST. 1275-P: Higher Branched-Chain Amino Acids in Youth with Type 2 Diabetes Paradoxically Increased by Short-Term Metformin Diabetes. 69. DOI: 10.2337/Db20-1275-P  0.249
1992 Narayanasami R, Otvos JD, Kasper CB, Shen A, Rajagopalan J, McCabe TJ, Okita JR, Hanahan DJ, Masters BSS. 31P NMR spectroscopic studies on purified, native and cloned, expressed forms of NADPH-cytochrome P450 reductase Biochemistry. 31: 4210-4218. PMID 1567869 DOI: 10.1021/Bi00132A009  0.245
2015 Cohen-Manheim I, Doniger GM, Sinnreich R, Simon ES, Pinchas-Mizrachi R, Otvos JD, Kark JD. Increase in the Inflammatory Marker GlycA over 13 Years in Young Adults Is Associated with Poorer Cognitive Function in Midlife. Plos One. 10: e0138036. PMID 26406330 DOI: 10.1371/Journal.Pone.0138036  0.241
2002 Freedman DS, Bowman BA, Otvos JD, Srinivasan SR, Berenson GS. Differences in the relation of obesity to serum triacylglycerol and VLDL subclass concentrations between black and white children: the Bogalusa Heart Study. The American Journal of Clinical Nutrition. 75: 827-33. PMID 11976155 DOI: 10.1093/Ajcn/75.5.827  0.241
1994 Delnomdedieu M, Basti MM, Otvos JD, Thomas DJ. Reduction and binding of arsenate and dimethylarsinate by glutathione: a magnetic resonance study Chemico-Biological Interactions. 90: 139-155. PMID 8156604 DOI: 10.1016/0009-2797(94)90099-X  0.238
2024 Garcia E, Shalaurova I, Matyus SP, Freeman LA, Neufeld EB, Sampson ML, Zubirán R, Wolska A, Remaley AT, Otvos JD, Connelly MA. A High-Throughput NMR Method for Lipoprotein-X Quantification. Molecules (Basel, Switzerland). 29. PMID 38338310 DOI: 10.3390/molecules29030564  0.235
2023 Tebar WR, Meneghini V, Goulart AC, Santos IS, Santos RD, Bittencourt MS, Generoso G, Pereira AC, Blaha MJ, Jones SR, Toth PP, Otvos JD, Lotufo PA, Bensenor IM. Combined Association of Novel and Traditional Inflammatory Biomarkers With Carotid Artery Plaque: GlycA Versus C-Reactive Protein (ELSA-Brasil). The American Journal of Cardiology. 204: 140-150. PMID 37542984 DOI: 10.1016/j.amjcard.2023.07.034  0.234
2022 Sampson M, Wolska A, Cole J, Zubirán R, Otvos JD, Meeusen JW, Donato LJ, Jaffe AS, Remaley AT. Accuracy and Clinical Impact of Estimating Low-Density Lipoprotein-Cholesterol at High and Low Levels by Different Equations. Biomedicines. 10. PMID 36551912 DOI: 10.3390/biomedicines10123156  0.233
2019 Ross LM, Slentz CA, Shalaurova I, Connelly MA, Otvos JD, Houmard JA, Kraus WE. Abstract MP59: The Differential Effects of Amount and Intensity of Aerobic Exercise Training on MVX, a Novel Mortality Risk Multimarker Circulation. 139. DOI: 10.1161/Circ.139.Suppl_1.Mp59  0.228
1985 Otvos JD, Engeseth HR, Wehrli S. Preparation and 113Cd NMR studies of homogeneous reconstituted metallothionein: reaffirmation of the two-cluster arrangement of metals Biochemistry. 24: 6735-6740. PMID 4074723 DOI: 10.1021/Bi00345A001  0.228
1992 Nettesheim DG, Harder SR, Feinberg BA, Otvos JD. Sequential resonance assignments of oxidized high-potential iron-sulfur protein from Chromatium vinosum. Biochemistry. 31: 1234-1244. PMID 1734968 DOI: 10.1021/Bi00119A037  0.227
1993 Delnomdedieu M, Basti MM, Otvos JD, Thomas DJ. Transfer of arsenite from glutathione to dithiols: a model of interaction. Chemical Research in Toxicology. 6: 598-602. PMID 8292735 DOI: 10.1021/Tx00035A002  0.225
2001 Zangger K, Shen G, Oz G, Otvos JD, Armitage IM. Oxidative dimerization in metallothionein is a result of intermolecular disulphide bonds between cysteines in the alpha-domain. The Biochemical Journal. 359: 353-60. PMID 11583581 DOI: 10.1042/0264-6021:3590353  0.219
1994 Holman DA, Thompson AW, Bennett DW, Otvos JD. Quantitative Determination of Sulfur-Oxygen Anion Concentrations in Aqueous Solution: Multicomponent Analysis of Attenuated Total Reflectance Infrared Spectra Analytical Chemistry. 66: 1378-1384. DOI: 10.1021/Ac00081A004  0.217
1999 Zangger K, Oz G, Otvos JD, Armitage IM. Three-dimensional solution structure of mouse [Cd7]-metallothionein-1 by homonuclear and heteronuclear NMR spectroscopy. Protein Science : a Publication of the Protein Society. 8: 2630-8. PMID 10631978 DOI: 10.1110/Ps.8.12.2630  0.215
1994 Xu RX, Nettesheim D, Otvos JD, Petering DH. NMR determination of the structures of peroxycobalt(III) bleomycin and cobalt(III) bleomycin, products of the aerobic oxidation of cobalt(II) bleomycin by dioxygen Biochemistry. 33: 907-916. PMID 7508261 DOI: 10.1021/Bi00170A009  0.212
1998 Li H, Otvos JD. Biphasic kinetics of Zn2+ removal from Zn metallothionein by nitrilotriacetate are associated with differential reactivity of the two metal clusters. Journal of Inorganic Biochemistry. 70: 187-94. PMID 9720304 DOI: 10.1016/S0162-0134(98)10013-2  0.212
2009 Brown AJ, Setji TL, Sanders LL, Lowry KP, Otvos JD, Kraus WE, Svetkey PL. Effects of exercise on lipoprotein particles in women with polycystic ovary syndrome. Medicine and Science in Sports and Exercise. 41: 497-504. PMID 19204602 DOI: 10.1249/MSS.0b013e31818c6c0c  0.211
2023 Sawicki KT, Ning H, Allen NB, Carnethon MR, Wallia A, Otvos JD, Ben-Sahra I, McNally EM, Snell-Bergeon JK, Wilkins JT. Longitudinal trajectories of branched chain amino acids through young adulthood and diabetes in later life. Jci Insight. 8. PMID 37092552 DOI: 10.1172/jci.insight.166956  0.206
1985 Nettesheim DG, Engeseth HR, Otvos JD. Products of metal exchange reactions of metallothionein Biochemistry. 24: 6744-6751. PMID 4074725 DOI: 10.1021/Bi00345A003  0.204
2002 Otvos JD, Jeyarajah EJ, Cromwell WC. Measurement issues related to lipoprotein heterogeneity. The American Journal of Cardiology. 90: 22i-29i. PMID 12419478  0.198
2021 Chung ST, Matta ST, Meyers AG, Cravalho CK, Villalobos-Perez A, Dawson JM, Sharma VR, Sampson ML, Otvos JD, Magge SN. Nuclear Magnetic Resonance Derived Biomarkers for Evaluating Cardiometabolic Risk in Youth and Young Adults Across the Spectrum of Glucose Tolerance. Frontiers in Endocrinology. 12: 665292. PMID 34084151 DOI: 10.3389/fendo.2021.665292  0.197
1996 Li H, Otvos JD. HPLC characterization of Ag+ and Cu+ metal exchange reactions with Zn- and Cd-metallothioneins. Biochemistry. 35: 13937-45. PMID 8909291 DOI: 10.1021/Bi961402F  0.194
2002 Otvos JD. Measurement of lipoprotein subclass profiles by nuclear magnetic resonance spectroscopy. Clinical Laboratory. 48: 171-80. PMID 11934219  0.193
2003 Hammad SM, Powell-Braxton L, Otvos JD, Eldridge L, Won W, Lyons TJ. Lipoprotein subclass profiles of hyperlipidemic diabetic mice measured by nuclear magnetic resonance spectroscopy Metabolism: Clinical and Experimental. 52: 916-921. PMID 12870170 DOI: 10.1016/S0026-0495(03)00058-1  0.193
1996 Li H, Otvos JD. 111Cd NMR studies of the domain specificity of Ag+ and Cu+ binding to metallothionein. Biochemistry. 35: 13929-36. PMID 8909290 DOI: 10.1021/Bi961401N  0.191
2021 Garcia E, Connelly MA, Matyus SP, Otvos JD, Shalaurova I. High-throughput nuclear magnetic resonance measurement of citrate in serum and plasma in the clinical laboratory. Practical Laboratory Medicine. 25: e00213. PMID 33869707 DOI: 10.1016/j.plabm.2021.e00213  0.19
2000 Zangger K, Oz G, Otvos J, Armitage I. 1H Chemical Shift Assignements for mouse [Cd7]-metallothionein-1 Journal of Back and Musculoskeletal Rehabilitation. DOI: 10.13018/Bmr4462  0.189
2002 Kraus WE, Houmard JA, Duscha BD, Knetzger KJ, Wharton MB, McCartney JS, Bales CW, Henes S, Samsa GP, Otvos JD, Kulkarni KR, Slentz CA. Effects of the amount and intensity of exercise on plasma lipoproteins. The New England Journal of Medicine. 347: 1483-92. PMID 12421890 DOI: 10.1056/Nejmoa020194  0.186
2022 Huffman KM, Parker DC, Bhapkar M, Racette SB, Martin CK, Redman LM, Das SK, Connelly MA, Pieper CF, Orenduff M, Ross LM, Ramaker ME, Dorling JL, Rosen CJ, Shalaurova I, ... Otvos JD, et al. Calorie restriction improves lipid-related emerging cardiometabolic risk factors in healthy adults without obesity: Distinct influences of BMI and sex from CALERIE™ a multicentre, phase 2, randomised controlled trial. Eclinicalmedicine. 43: 101261. PMID 35028547 DOI: 10.1016/j.eclinm.2021.101261  0.177
2023 Otvos JD, Shalaurova I, May HT, Muhlestein JB, Wilkins JT, McGarrah RW, Kraus WE. Multimarkers of metabolic malnutrition and inflammation and their association with mortality risk in cardiac catheterisation patients: a prospective, longitudinal, observational, cohort study. The Lancet. Healthy Longevity. 4: e72-e82. PMID 36738747 DOI: 10.1016/S2666-7568(23)00001-6  0.175
1995 Petering DH, Mao Q, Fulmer P, DeRose E, Otvos JD, Antholine WE. Structural features of metallobleomycins bound to DNA Journal of Inorganic Biochemistry. 59: 202. DOI: 10.1016/0162-0134(95)97308-D  0.171
2021 Ross LM, Slentz CA, Zidek AM, Huffman KM, Shalaurova I, Otvos JD, Connelly MA, Kraus VB, Bales CW, Houmard JA, Kraus WE. Effects of Amount, Intensity, and Mode of Exercise Training on Insulin Resistance and Type 2 Diabetes Risk in the STRRIDE Randomized Trials. Frontiers in Physiology. 12: 626142. PMID 33613319 DOI: 10.3389/fphys.2021.626142  0.169
2018 Danford CJ, Connelly MA, Shalaurova I, Kim M, Herman MA, Nasser I, Otvos JD, Afdhal NH, Jiang ZG, Lai M. A Pathophysiologic Approach Combining Genetics and Insulin Resistance to Predict the Severity of Nonalcoholic Fatty Liver Disease. Hepatology Communications. 2: 1467-1478. PMID 30556036 DOI: 10.1002/hep4.1267  0.168
2008 Riddler SA, Li X, Otvos J, Post W, Palella F, Kingsley L, Visscher B, Jacobson LP, Sharrett AR. Antiretroviral therapy is associated with an atherogenic lipoprotein phenotype among HIV-1-infected men in the Multicenter AIDS Cohort Study. Journal of Acquired Immune Deficiency Syndromes (1999). 48: 281-8. PMID 18545156 DOI: 10.1097/Qai.0B013E31817Bbbf0  0.164
2022 Wilkins JT, Ning H, Sniderman A, Stone N, Otvos J, Jacobs DR, Shah R, Murthy VL, Rana JS, Allen N, Lloyd-Jones DM. Analysis of apoB concentrations across early adulthood and predictors for rates of change using CARDIA study data. Journal of Lipid Research. 100299. PMID 36272600 DOI: 10.1016/j.jlr.2022.100299  0.152
2015 Jin R, Le NA, Cleeton R, Sun X, Cruz Muños J, Otvos J, Vos MB. Amount of hepatic fat predicts cardiovascular risk independent of insulin resistance among Hispanic-American adolescents. Lipids in Health and Disease. 14: 39. PMID 25925168 DOI: 10.1186/s12944-015-0038-x  0.151
2022 Waksman O, Cho DJ, Kim H, Otvos JD, Rosenson RS. Lipoprotein-X and Lipoprotein-Z Induced Hyperviscosity Syndrome in the Setting of Cholestatic Liver Failure. Jacc. Case Reports. 4: 1348-1352. PMID 36299645 DOI: 10.1016/j.jaccas.2022.09.001  0.149
2023 Shemesh E, Chevli PA, Islam T, German CA, Otvos J, Yeboah J, Rodriguez F, deFilippi C, Lima JAC, Blaha M, Pandey A, Vaduganathan M, Shapiro MD. Circulating ketone bodies and cardiovascular outcomes: the MESA study. European Heart Journal. PMID 36881667 DOI: 10.1093/eurheartj/ehad087  0.148
2022 Noel M, Chasman DI, Mora S, Otvos JD, Palmer CD, Parsons PJ, Smoller JW, Cummings RD, Mealer RG. The Inflammation Biomarker GlycA Reflects Plasma N-Glycan Branching. Clinical Chemistry. PMID 36254612 DOI: 10.1093/clinchem/hvac160  0.14
2021 Jang S, Ogunmoroti O, Zhao D, Fashanu OE, Tibuakuu M, Benson EM, Norby F, Otvos JD, Heckbert SR, Szklo M, Michos ED. The association of novel inflammatory marker GlycA and incident atrial fibrillation in the Multi-Ethnic Study of Atherosclerosis (MESA). Plos One. 16: e0248644. PMID 33765041 DOI: 10.1371/journal.pone.0248644  0.138
2022 Kraus VB, Ma S, Tourani R, Fillenbaum GG, Burchett BM, Parker DC, Kraus WE, Connelly MA, Otvos JD, Cohen HJ, Orenduff MC, Pieper CF, Zhang X, Aliferis CF. Causal analysis identifies small HDL particles and physical activity as key determinants of longevity of older adults. Ebiomedicine. 85: 104292. PMID 36182774 DOI: 10.1016/j.ebiom.2022.104292  0.138
2024 Joo J, Shearer JJ, Wolska A, Remaley AT, Otvos JD, Connelly MA, Sampson M, Bielinski SJ, Larson NB, Park H, Conners KM, Turecamo S, Roger VL. Incremental Value of a Metabolic Risk Score for Heart Failure Mortality: A Population-Based Study. Circulation. Genomic and Precision Medicine. e004312. PMID 38516784 DOI: 10.1161/CIRCGEN.123.004312  0.13
2023 Conners KM, Shearer JJ, Joo J, Park H, Manemann SM, Remaley AT, Otvos JD, Connelly MA, Sampson M, Bielinski SJ, Wolska A, Turecamo S, Roger VL. The Metabolic Vulnerability Index: A Novel Marker for Mortality Prediction in Heart Failure. Jacc. Heart Failure. PMID 37480881 DOI: 10.1016/j.jchf.2023.06.013  0.122
2024 Kumar S, Conners KM, Shearer JJ, Joo J, Turecamo S, Sampson M, Wolska A, Remaley AT, Connelly MA, Otvos JD, Larson NB, Bielinski SJ, Roger VL. Frailty and Metabolic Vulnerability in Heart Failure: A Community Cohort Study. Journal of the American Heart Association. e031616. PMID 38533960 DOI: 10.1161/JAHA.123.031616  0.12
2020 Flores-Guerrero JL, Westenbrink BD, Connelly MA, Otvos JD, Groothof D, Shalaurova I, Garcia E, Navis G, de Boer RA, Bakker SJL, Dullaart RPF. Association of beta-hydroxybutyrate with development of heart failure: Sex differences in a Dutch population cohort. European Journal of Clinical Investigation. e13468. PMID 33616911 DOI: 10.1111/eci.13468  0.11
2023 Sampson M, Wolska A, Meeusen JW, Otvos J, Remaley AT. The Sampson-NIH Equation Is the Preferred Calculation Method for LDL-C. Clinical Chemistry. PMID 38006320 DOI: 10.1093/clinchem/hvad190  0.107
2022 Riggs KA, Joshi PH, Khera A, Otvos JD, Greenland P, Ayers CR, Rohatgi A. GlycA, hsCRP differentially associated with MI, ischemic stroke: In the Dallas Heart Study and Multi-Ethnic Study of Atherosclerosis: GlycA, hsCRP Differentially Associated MI, Stroke. American Journal of Preventive Cardiology. 12: 100373. PMID 36061365 DOI: 10.1016/j.ajpc.2022.100373  0.091
2021 Anderson AM, Bhondoekhan F, Curanovic D, Connelly MA, Otvos JD, Post WS, Michos ED, Lahiri C, Wolinsky S, Levine A, Seaberg EC, Rubin LH, Vance DE, Becker JT. GlycA is associated with neuropsychological impairment in men with HIV. Aids (London, England). 36: 156-159. PMID 34873097 DOI: 10.1097/QAD.0000000000003094  0.063
2022 Anderson AM, Bhondoekhan F, Curanovic D, Connelly MA, Otvos JD, Post WS, Michos ED, Stosor V, Levine A, Seaberg E, Weinstein AM, Becker JT. Higher soluble CD163 in blood is associated with significant depression symptoms in men with HIV. Journal of Acquired Immune Deficiency Syndromes (1999). PMID 35969468 DOI: 10.1097/QAI.0000000000003063  0.056
2024 Oyetoro RO, Conners KM, Joo J, Turecamo S, Sampson M, Wolska A, Remaley AT, Otvos JD, Connelly MA, Larson NB, Bielinski SJ, Hashemian M, Shearer JJ, Roger VL. Circulating ketone bodies and mortality in heart failure: a community cohort study. Frontiers in Cardiovascular Medicine. 11: 1293901. PMID 38327494 DOI: 10.3389/fcvm.2024.1293901  0.054
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