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Simon H. Friedman, Ph.D. - Publications

Affiliations: 
Pharmaceutical Sciences University of Missouri Kansas City 
Area:
Bioorganic Chemistry/Chemical Biology
Website:
http://friedmanlaboratory.org/
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32 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Nadendla K, Chintala S, Kover K, Friedman SH. In vivo variable and multi-day response from an insulin-releasing photoactivated depot. Bioorganic & Medicinal Chemistry Letters. 92: 129388. PMID 37369330 DOI: 10.1016/j.bmcl.2023.129388  0.744
2019 Friedman SH. Replacing Pumps with Light Controlled Insulin Delivery. Current Diabetes Reports. 19: 122. PMID 31696345 DOI: 10.1007/S11892-019-1233-3  0.415
2019 Sarode BR, Kover K, Friedman SH. Visible-Light-Activated High-Density Materials for Controlled in Vivo Insulin Release. Molecular Pharmaceutics. PMID 31647241 DOI: 10.1021/Acs.Molpharmaceut.9B00806  0.506
2019 Nadendla K, Sarode B, Friedman SH. Chemical modification of proteins with photocleavable groups. Methods in Enzymology. 624: 113-128. PMID 31370926 DOI: 10.1016/Bs.Mie.2019.04.008  0.711
2019 Nadendla K, Sarode BR, Friedman SH. Hydrophobic Tags for Highly Efficient Light Activated Protein Release. Molecular Pharmaceutics. PMID 31117739 DOI: 10.1021/Acs.Molpharmaceut.9B00140  0.746
2018 Jain N, Friedman SH. Multiple weak intercalation as a strategy for the inhibition of polymerases. Bioorganic & Medicinal Chemistry Letters. PMID 30579791 DOI: 10.1016/J.Bmcl.2018.12.027  0.313
2018 Jain N, Friedman SH. A Tetra-Orthogonal Strategy for the Efficient Synthesis of Scaffolds Based on Cyclic Peptides. International Journal of Peptide Research and Therapeutics. 24: 535-542. PMID 30416404 DOI: 10.1007/S10989-017-9642-0  0.324
2018 Jain PK, Friedman SH. The ULTIMATE Reagent: A Universal Photo-Cleavable & Clickable Reagent for the Regiospecific and Reversible End Labeling of Any Nucleic Acid. Chembiochem : a European Journal of Chemical Biology. PMID 29516677 DOI: 10.1002/Cbic.201800028  0.525
2018 Jain PK, Friedman SH. Front Cover: The ULTIMATE Reagent: A Universal Photocleavable and Clickable Reagent for the Regiospecific and Reversible End Labeling of Any Nucleic Acid (ChemBioChem 12/2018) Chembiochem. 19: 1196-1196. DOI: 10.1002/Cbic.201800282  0.461
2017 Nadendla K, Friedman SH. Light Control of Protein Solubility Through Isoelectric Point Modulation. Journal of the American Chemical Society. 139: 17861-17869. PMID 29192764 DOI: 10.1021/Jacs.7B08465  0.747
2016 Sarode BR, Kover K, Tong PY, Zhang C, Friedman SH. Light Control of Insulin Release and Blood Glucose Using an Injectable Photoactivated Depot. Molecular Pharmaceutics. PMID 27653828 DOI: 10.1021/Acs.Molpharmaceut.6B00633  0.465
2016 Sarode BR, Jain PK, Friedman SH. Macromol. Biosci. 8/2016. Macromolecular Bioscience. 16: 1250. PMID 27491330 DOI: 10.1002/Mabi.201670032  0.581
2016 Sarode BR, Jain PK, Friedman SH. Polymerizing Insulin with Photocleavable Linkers to Make Light-Sensitive Macropolymer Depot Materials. Macromolecular Bioscience. PMID 27171861 DOI: 10.1002/Mabi.201500471  0.623
2014 Kala A, Jain PK, Friedman SH. Patterning of cells through patterning of biology. Molecular Biosystems. 10: 1689-92. PMID 24531692 DOI: 10.1039/C3Mb70587K  0.505
2014 Kala A, Jain PK, Karunakaran D, Shah S, Friedman SH. The synthesis of tetra-modified RNA for the multidimensional control of gene expression via light-activated RNA interference. Nature Protocols. 9: 11-20. PMID 24309973 DOI: 10.1038/Nprot.2013.165  0.636
2013 Jain PK, Karunakaran D, Friedman SH. Construction of a photoactivated insulin depot. Angewandte Chemie (International Ed. in English). 52: 1404-9. PMID 23208858 DOI: 10.1002/Anie.201207264  0.604
2012 Jain N, Francis S, Friedman SH. Inhibition of therapeutically important polymerases with high affinity bis-intercalators. Bioorganic & Medicinal Chemistry Letters. 22: 4844-8. PMID 22695131 DOI: 10.1016/J.Bmcl.2012.05.041  0.303
2011 Kala A, Friedman SH. Enhanced light-activated RNA interference using phosphorothioate-based dsRNA precursors of siRNA. Pharmaceutical Research. 28: 3050-7. PMID 21739319 DOI: 10.1007/S11095-011-0529-Z  0.392
2011 Jain PK, Shah S, Friedman SH. Patterning of gene expression using new photolabile groups applied to light activated RNAi. Journal of the American Chemical Society. 133: 440-6. PMID 21162570 DOI: 10.1021/Ja107226E  0.632
2009 Shah S, Jain PK, Kala A, Karunakaran D, Friedman SH. Light-activated RNA interference using double-stranded siRNA precursors modified using a remarkable regiospecificity of diazo-based photolabile groups. Nucleic Acids Research. 37: 4508-17. PMID 19477960 DOI: 10.1093/Nar/Gkp415  0.641
2008 Shah S, Friedman SH. An ESI-MS method for characterization of native and modified oligonucleotides used for RNA interference and other biological applications. Nature Protocols. 3: 351-6. PMID 18323805 DOI: 10.1038/Nprot.2007.535  0.504
2007 Shah S, Friedman SH. Tolerance of RNA interference toward modifications of the 5' antisense phosphate of small interfering RNA. Oligonucleotides. 17: 35-43. PMID 17461761 DOI: 10.1089/Oli.2006.0067  0.54
2007 Rangarajan S, Friedman SH. Design, synthesis, and evaluation of phenanthridine derivatives targeting the telomerase RNA/DNA heteroduplex. Bioorganic & Medicinal Chemistry Letters. 17: 2267-73. PMID 17317174 DOI: 10.1016/J.Bmcl.2007.01.070  0.33
2005 Shah S, Rangarajan S, Friedman SH. Light-activated RNA interference. Angewandte Chemie (International Ed. in English). 44: 1328-32. PMID 15643658 DOI: 10.1002/Anie.200461458  0.507
2001 West C, Francis R, Friedman SH. Small molecule/nucleic acid affinity chromatography: application for the identification of telomerase inhibitors which target its key RNA/DNA heteroduplex. Bioorganic & Medicinal Chemistry Letters. 11: 2727-30. PMID 11591511 DOI: 10.1016/S0960-894X(01)00553-4  0.317
2001 Francis R, West C, Friedman SH. Targeting telomerase via its key RNA/DNA heteroduplex. Bioorganic Chemistry. 29: 107-17. PMID 11300699 DOI: 10.1006/Bioo.2000.1196  0.308
1998 Friedman SH, Ganapathi PS, Rubin Y, Kenyon GL. Optimizing the binding of fullerene inhibitors of the HIV-1 protease through predicted increases in hydrophobic desolvation. Journal of Medicinal Chemistry. 41: 2424-9. PMID 9632374 DOI: 10.1021/Jm970689R  0.469
1997 Friedman SH, Kenyon GL. A computational strategy for the design of regiospecific syntheses of fullerene derivatives Journal of the American Chemical Society. 119: 447-448. DOI: 10.1021/Ja963041X  0.424
1995 Ganapathi PS, Friedman SH, Kenyon GL, Rubin Y. Sequential "double-Michael" additions of dienolates with C60: Rapid access to sterically congested buckminsterfullerene derivatives with defined stereochemistry The Journal of Organic Chemistry. 60: 2954-2955. DOI: 10.1021/Jo00115A002  0.458
1993 Sijbesma R, Srdanov G, Wudl F, Castoro JA, Wilkins C, Friedman SH, DeCamp DL, Kenyon GL. Synthesis of a fullerene derivative for the inhibition of HIV enzymes Journal of the American Chemical Society. 115: 6510-6512. DOI: 10.1021/Ja00068A006  0.501
1993 Friedman SH, Decamp DL, Sijbesma RP, Srdanov G, Wudl F, Kenyon GL. Inhibition of the HIV-1 protease by fullerene derivatives: Model building studies and experimental verification Journal of the American Chemical Society. 115: 6506-6509. DOI: 10.1021/Ja00068A005  0.499
1993 Sijbesma R, Srdanov G, Wudl F, Castoro JA, Wilkins C, Friedman SH, Decamp DL, Kenyon GL. Synthesis of a fullerene derivative for the Inhibition of HIV enzymes Journal of the American Chemical Society. 115: 6510-6512.  0.438
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