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Renato J. Aguilera - Publications

Affiliations: 
University of California, Los Angeles, Los Angeles, CA 
Area:
Molecular Biology, Genetics, Cell Biology
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41 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Swain RM, Contreras L, Varela-Ramirez A, Hossain M, Das U, Valenzuela CA, Penichet ML, Dimmock JR, Aguilera RJ. Two novel piperidones induce apoptosis and antiproliferative effects on human prostate and lymphoma cancer cell lines. Investigational New Drugs. PMID 35793039 DOI: 10.1007/s10637-022-01266-y  0.31
2022 Gutierrez DA, Contreras L, Villanueva PJ, Borrego EA, Morán-Santibañez K, Hess JD, DeJesus R, Larragoity M, Betancourt AP, Mohl JE, Robles-Escajeda E, Begum K, Roy S, Kirken RA, Varela-Ramirez A, ... Aguilera RJ, et al. Identification of a Potent Cytotoxic Pyrazole with Anti-Breast Cancer Activity That Alters Multiple Pathways. Cells. 11. PMID 35053370 DOI: 10.3390/cells11020254  0.308
2020 Tilekar K, Upadhyay N, Schweipert M, Hess JD, Macias LH, Mrowka P, Meyer-Almes FJ, Aguilera RJ, Iancu CV, Choe JY, Ramaa CS. Permuted 2,4-thiazolidinedione (TZD) analogs as GLUT inhibitors and their in-vitro evaluation in leukemic cells. European Journal of Pharmaceutical Sciences : Official Journal of the European Federation For Pharmaceutical Sciences. 105512. PMID 32801003 DOI: 10.1016/J.Ejps.2020.105512  0.307
2020 Tilekar K, Upadhyay N, Hess JD, Macias LH, Mrowka P, Aguilera RJ, Meyer-Almes FJ, Iancu CV, Choe JY, Ramaa CS. Structure guided design and synthesis of furyl thiazolidinedione derivatives as inhibitors of GLUT 1 and GLUT 4, and evaluation of their anti-leukemic potential. European Journal of Medicinal Chemistry. 202: 112603. PMID 32634629 DOI: 10.1016/J.Ejmech.2020.112603  0.317
2020 Donoso-Bustamante V, Borrego EA, Schiaffino-Bustamante Y, Gutiérrez DA, Millas-Vargas JP, Fuentes-Retamal S, Correa P, Carrillo I, Aguilera RJ, Miranda D, Chávez-Báez I, Pulgar R, Urra FA, Varela-Ramírez A, Araya-Maturana R. An acylhydroquinone derivative produces OXPHOS uncoupling and sensitization to BH3 mimetic ABT-199 (Venetoclax) in human promyelocytic leukemia cells. Bioorganic Chemistry. 100: 103935. PMID 32454391 DOI: 10.1016/J.Bioorg.2020.103935  0.382
2020 Upadhyay N, Tilekar K, Jänsch N, Schweipert M, Hess JD, Henze Macias L, Mrowka P, Aguilera RJ, Choe JY, Meyer-Almes FJ, Ramaa CS. Discovery of novel N-substituted thiazolidinediones (TZDs) as HDAC8 inhibitors: in-silico studies, synthesis, and biological evaluation. Bioorganic Chemistry. 100: 103934. PMID 32446120 DOI: 10.1016/J.Bioorg.2020.103934  0.326
2020 Fratev F, Gutierrez DA, Aguilera RJ, Tyagi A, Damodaran C, Sirimulla S. Discovery of New AKT1 Inhibitors by Combination of Structure Based Virtual Screening Approaches and Biological Evaluations. Journal of Biomolecular Structure & Dynamics. 1-11. PMID 31933423 DOI: 10.1080/07391102.2020.1715835  0.31
2019 Khandaker TA, Hess JD, Aguilera R, Andrei G, Snoeck R, Schols D, Pradhan P, Lakshman MK. Synthesis and Evaluations of "1,4-Triazolyl Combretacoumarins" and Desmethoxy Analogues. European Journal of Organic Chemistry. 2019: 5610-5623. PMID 31579393 DOI: 10.1002/Ejoc.201900569  0.347
2019 Solis LH, Ayala-Marin YM, Portillo S, Varela-Ramírez A, Aguilera RJ, Boland T. Thermal inkjet bioprinting triggers the activation of the VEGF pathway in human microvascular endothelial cells in vitro. Biofabrication. PMID 31151129 DOI: 10.1088/1758-5090/Ab25F9  0.325
2019 Ruiz-Medina BE, Lerma D, Hwang M, Ross JA, Skouta R, Aguilera RJ, Kirken RA, Varela-Ramirez A, Robles-Escajeda E. Green barley mitigates cytotoxicity in human lymphocytes undergoing aggressive oxidative stress, via activation of both the Lyn/PI3K/Akt and MAPK/ERK pathways. Scientific Reports. 9: 6005. PMID 30979953 DOI: 10.1038/S41598-019-42228-4  0.302
2019 Iglesias-Figueroa BF, Siqueiros-Cendón TS, Gutierrez DA, Aguilera RJ, Espinoza-Sánchez EA, Arévalo-Gallegos S, Varela-Ramirez A, Rascón-Cruz Q. Recombinant human lactoferrin induces apoptosis, disruption of F-actin structure and cell cycle arrest with selective cytotoxicity on human triple negative breast cancer cells. Apoptosis : An International Journal On Programmed Cell Death. PMID 30941553 DOI: 10.1007/S10495-019-01539-7  0.393
2019 Gutierrez DA, DeJesus RE, Contreras L, Rodriguez-Palomares IA, Villanueva PJ, Balderrama KS, Monterroza L, Larragoity M, Varela-Ramirez A, Aguilera RJ. A new pyridazinone exhibits potent cytotoxicity on human cancer cells via apoptosis and poly-ubiquitinated protein accumulation. Cell Biology and Toxicology. PMID 30825052 DOI: 10.1007/S10565-019-09466-8  0.408
2018 Castro E, Cerón MR, Garcia AH, Kim Q, Etcheverry-Berríos A, Morel M, Díaz-Torres R, Qian W, Martinez Z, Mendez L, Perez F, Santoyo CA, Gimeno-Muñoz R, Esper R, Gutierrez DA, ... ... Aguilera RJ, et al. A new family of fullerene derivatives: Fullerene-curcumin conjugates for biological and photovoltaic applications. Rsc Advances. 8: 41692-41698. PMID 31543960 DOI: 10.1039/C8Ra08334G  0.306
2018 Villanueva PJ, Martinez A, Baca ST, DeJesus RE, Larragoity M, Contreras L, Gutierrez DA, Varela-Ramirez A, Aguilera RJ. Pyronaridine exerts potent cytotoxicity on human breast and hematological cancer cells through induction of apoptosis. Plos One. 13: e0206467. PMID 30395606 DOI: 10.1371/Journal.Pone.0206467  0.388
2018 Contreras L, Calderon RI, Varela-Ramirez A, Zhang HY, Quan Y, Das U, Dimmock JR, Skouta R, Aguilera RJ. Induction of apoptosis via proteasome inhibition in leukemia/lymphoma cells by two potent piperidones. Cellular Oncology (Dordrecht). PMID 30088262 DOI: 10.1007/S13402-018-0397-1  0.399
2016 Nunes LM, Hossain M, Varela-Ramirez A, DAS U, Ayala-Marin YM, Dimmock JR, Aguilera RJ. A novel class of piperidones exhibit potent, selective and pro-apoptotic anti-leukemia properties. Oncology Letters. 11: 3842-3848. PMID 27313705 DOI: 10.3892/Ol.2016.4480  0.396
2015 Oldham ED, Nunes LM, Varela-Ramirez A, Rankin SE, Knutson BL, Aguilera RJ, Lehmler HJ. Cytotoxic activity of triazole-containing alkyl β-D-glucopyranosides on a human T-cell leukemia cell line. Chemistry Central Journal. 9: 3. PMID 25705252 DOI: 10.1186/S13065-014-0072-1  0.366
2014 Nunes LM, Robles-Escajeda E, Santiago-Vazquez Y, Ortega NM, Lema C, Muro A, Almodovar G, Das U, Das S, Dimmock JR, Aguilera RJ, Varela-Ramirez A. The gender of cell lines matters when screening for novel anti-cancer drugs. The Aaps Journal. 16: 872-4. PMID 24875051 DOI: 10.1208/S12248-014-9617-4  0.354
2014 Santiago-Vazquez Y, Das S, Das U, Robles-Escajeda E, Ortega NM, Lema C, Varela-Ramírez A, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Novel 3,5-bis(arylidene)-4-oxo-1-piperidinyl dimers: structure-activity relationships and potent antileukemic and antilymphoma cytotoxicity. European Journal of Medicinal Chemistry. 77: 315-22. PMID 24657568 DOI: 10.1016/J.Ejmech.2014.03.009  0.393
2014 Pedroza DA, De Leon F, Varela-Ramirez A, Lema C, Aguilera RJ, Mito S. The cytotoxic effect of 2-acylated-1,4-naphthohydroquinones on leukemia/lymphoma cells. Bioorganic & Medicinal Chemistry. 22: 842-7. PMID 24368029 DOI: 10.1016/J.Bmc.2013.12.007  0.383
2013 Robles-Escajeda E, Martínez A, Varela-Ramirez A, Sánchez-Delgado RA, Aguilera RJ. Analysis of the cytotoxic effects of ruthenium-ketoconazole and ruthenium-clotrimazole complexes on cancer cells. Cell Biology and Toxicology. 29: 431-43. PMID 24272524 DOI: 10.1007/S10565-013-9264-Z  0.411
2013 Robles-Escajeda E, Lerma D, Nyakeriga AM, Ross JA, Kirken RA, Aguilera RJ, Varela-Ramirez A. Searching in mother nature for anti-cancer activity: anti-proliferative and pro-apoptotic effect elicited by green barley on leukemia/lymphoma cells. Plos One. 8: e73508. PMID 24039967 DOI: 10.1371/Journal.Pone.0073508  0.386
2011 Liu F, Anis R, Hwang E, Ovalle R, Varela-Ramírez A, Aguilera RJ, Contel M. Group 11 Metal Compounds with Tripodal Bis(imidazole) Thioether Ligands. Applications as Catalysts in the Oxidation of Alkenes and as Antimicrobial Agents. Molecules (Basel, Switzerland). 16: 6701-20. PMID 25134773 DOI: 10.3390/Molecules16086701  0.309
2011 González-Pantoja JF, Stern M, Jarzecki AA, Royo E, Robles-Escajeda E, Varela-Ramírez A, Aguilera RJ, Contel M. Titanocene-phosphine derivatives as precursors to cytotoxic heterometallic TiAu2 and TiM (M = Pd, Pt) compounds. Studies of their interactions with DNA. Inorganic Chemistry. 50: 11099-110. PMID 21958150 DOI: 10.1021/Ic201647H  0.309
2011 Das S, Das U, Varela-Ramírez A, Lema C, Aguilera RJ, Balzarini J, De Clercq E, Dimmock SG, Gorecki DK, Dimmock JR. Bis[3,5-bis(benzylidene)-4-oxo-1-piperidinyl]amides: a novel class of potent cytotoxins. Chemmedchem. 6: 1892-9. PMID 21826795 DOI: 10.1002/Cmdc.201100199  0.368
2011 Varela-Ramirez A, Costanzo M, Carrasco YP, Pannell KH, Aguilera RJ. Cytotoxic effects of two organotin compounds and their mode of inflicting cell death on four mammalian cancer cells. Cell Biology and Toxicology. 27: 159-68. PMID 21069563 DOI: 10.1007/S10565-010-9178-Y  0.397
2010 Martínez A, Rajapakse CS, Sánchez-Delgado RA, Varela-Ramirez A, Lema C, Aguilera RJ. Arene-Ru(II)-chloroquine complexes interact with DNA, induce apoptosis on human lymphoid cell lines and display low toxicity to normal mammalian cells. Journal of Inorganic Biochemistry. 104: 967-77. PMID 20605217 DOI: 10.1016/J.Jinorgbio.2010.05.002  0.368
2009 Elie BT, Levine C, Ubarretxena-Belandia I, Varela-Ramírez A, Aguilera RJ, Ovalle R, Contel M. Water Soluble Phosphane-Gold(I) Complexes. Applications as Recyclable Catalysts in a Three-component Coupling Reaction and as Antimicrobial and Anticancer Agents. European Journal of Inorganic Chemistry. 2009: 3421-3430. PMID 23524957 DOI: 10.1002/Ejic.200900279  0.335
2009 Shaik N, Martínez A, Augustin I, Giovinazzo H, Varela-Ramírez A, Sanaú M, Aguilera RJ, Contel M. Synthesis of apoptosis-inducing iminophosphorane organogold(III) complexes and study of their interactions with biomolecular targets. Inorganic Chemistry. 48: 1577-87. PMID 19146434 DOI: 10.1021/Ic801925K  0.314
2006 Seong CS, Varela-Ramirez A, Aguilera RJ. DNase II deficiency impairs innate immune function in Drosophila. Cellular Immunology. 240: 5-13. PMID 16854402 DOI: 10.1016/J.Cellimm.2006.05.007  0.302
2005 Montoya J, Varela-Ramirez A, Shanmugasundram M, Martinez LE, Primm TP, Aguilera RJ. Tandem screening of toxic compounds on GFP-labeled bacteria and cancer cells in microtiter plates. Biochemical and Biophysical Research Communications. 335: 367-72. PMID 16081045 DOI: 10.1016/J.Bbrc.2005.07.086  0.352
2004 Montoya J, Varela-Ramirez A, Estrada A, Martinez LE, Garza K, Aguilera RJ. A fluorescence-based rapid screening assay for cytotoxic compounds. Biochemical and Biophysical Research Communications. 325: 1517-23. PMID 15555600 DOI: 10.1016/J.Bbrc.2004.10.196  0.367
2003 Evans CJ, Aguilera RJ. DNase II: genes, enzymes and function. Gene. 322: 1-15. PMID 14644493 DOI: 10.1016/J.Gene.2003.08.022  0.304
2002 Evans CJ, Merriam JR, Aguilera RJ. Drosophila acid DNase is a homolog of mammalian DNase II. Gene. 295: 61-70. PMID 12242012 DOI: 10.1016/S0378-1119(02)00819-3  0.314
2002 Solorzano-Vargas RS, Wang J, Jiang L, Tsai HV, Ontiveros LO, Vazir MA, Aguilera RJ, Martín MG. Multiple transcription factors in 5'-flanking region of human polymeric Ig receptor control its basal expression. American Journal of Physiology. Gastrointestinal and Liver Physiology. 283: G415-25. PMID 12121890 DOI: 10.1152/Ajpgi.00420.2001  0.301
2000 Lyon CJ, Evans CJ, Bill BR, Otsuka AJ, Aguilera RJ. The C. elegans apoptotic nuclease NUC-1 is related in sequence and activity to mammalian DNase II. Gene. 252: 147-54. PMID 10903446 DOI: 10.1016/S0378-1119(00)00213-4  0.322
1996 Lyon CJ, Miranda GA, Piao JS, Aguilera RJ. Characterization of an endonuclease activity which preferentially cleaves the G-rich immunoglobulin switch repeat sequences Molecular Immunology. 33: 157-169. PMID 8649437 DOI: 10.1016/0161-5890(95)00125-5  0.311
1995 Casillas AM, Thompson AD, Cheshier S, Hernandez S, Aguilera RJ. RAG-1 and RAG-2 gene expression and V(D)J recombinase activity are enhanced by protein phosphatase 1 and 2A inhibition in lymphocyte cell lines. Molecular Immunology. 32: 167-75. PMID 7898493 DOI: 10.1016/0161-5890(94)00142-N  0.339
1987 Aguilera RJ, Akira S, Okazaki K, Sakano H. A pre-B cell nuclear protein that specifically interacts with the immunoglobulin V-J recombination sequences. Cell. 51: 909-17. PMID 3500792 DOI: 10.1016/0092-8674(87)90578-2  0.326
1986 Hope TJ, Aguilera RJ, Minie ME, Sakano H. Endonucleolytic activity that cleaves immunoglobulin recombination sequences. Science (New York, N.Y.). 231: 1141-5. PMID 3003919 DOI: 10.1126/Science.3003919  0.304
1985 Aguilera RJ, Hope TJ, Sakano H. Characterization of immunoglobulin enhancer deletions in murine plasmacytomas. The Embo Journal. 4: 3689-3693. DOI: 10.1002/J.1460-2075.1985.Tb04136.X  0.301
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