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John R. Vane, Ph.D. - Publications

Affiliations: 
Wellcome Foundation 
Area:
Platelets, prostaglandins
Website:
http://www.nobelprize.org/nobel_prizes/medicine/laureates/1982/vane-bio.html

441 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2010 Hughes J, Vane JR. An analysis of the responses of the isolated portal vein of the rabbit to electrical stimulation and to drugs. British Journal of Pharmacology and Chemotherapy. 30: 46-66. PMID 19108249 DOI: 10.1111/J.1476-5381.1967.TB02112.X  0.248
2010 Handschumacher RE, Vane JR. The relationship between the penetration of tryptamine and 5-hydroxytryptamine into smooth muscle and the associated contractions. British Journal of Pharmacology and Chemotherapy. 29: 105-18. PMID 19108234 DOI: 10.1111/j.1476-5381.1967.tb01944.x  0.208
2007 VANE JR. Some pharmacological actions of paludrine. British Journal of Pharmacology and Chemotherapy. 4: 14-21. PMID 18113148 DOI: 10.1111/J.1476-5381.1949.TB00510.X  0.238
2007 VANE JR. The action of choline derivatives on isolated rabbit auricles when arrested by paludrine. British Journal of Pharmacology and Chemotherapy. 3: 341-5. PMID 18102605 DOI: 10.1111/J.1476-5381.1948.TB00398.X  0.263
2005 Vane JR. Adventures and excursions in bioassay: the stepping stones to prostacylin. Bioscience Reports. 24: 254-79. PMID 16134015 DOI: 10.1007/S10540-005-2734-7  0.186
2004 Smith CG, Vane JR. The discovery of captopril: a reply. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 18: 935. PMID 15173103 DOI: 10.1096/fj.04-1992lte  0.194
2004 THOMPSON JE, VANE JR. Effect of venous occlusion on peripheral arterial blood-flow. Lancet (London, England). 1: 380-2. PMID 14805073 DOI: 10.1016/S0140-6736(51)92089-2  0.263
2004 Vane J, Corin RE. Prostacyclin: a vascular mediator. European Journal of Vascular and Endovascular Surgery : the Official Journal of the European Society For Vascular Surgery. 26: 571-8. PMID 14603414 DOI: 10.1016/S1078-5884(03)00385-X  0.275
2003 Vane JR, Botting RM. The mechanism of action of aspirin. Thrombosis Research. 110: 255-258. PMID 14592543 DOI: 10.1016/S0049-3848(03)00379-7  0.433
2003 VANE JR. A new perfusion method. The Journal of Physiology. 121: 97-105. PMID 13085302 DOI: 10.1113/jphysiol.1953.sp004933  0.196
2003 Smith CG, Vane JR. The discovery of captopril. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 788-9. PMID 12724335 DOI: 10.1096/fj.03-0093life  0.191
2003 Vane J. The mechanism of action of anti-inflammatory drugs. International Journal of Clinical Practice. Supplement. 2. PMID 12723738  0.257
2002 Warner TD, Mitchell JA, Vane JR. Cyclo-oxygenase-2 inhibitors and cardiovascular events [10] Lancet. 360: 1700-1701. PMID 12457830 DOI: 10.1016/S0140-6736(02)11635-7  0.353
2002 Vane JR. Biomedicine. Back to an aspirin a day? Science (New York, N.Y.). 296: 474-5. PMID 11964462 DOI: 10.1126/Science.1071702  0.411
2000 VANE JR. The relative activities of some tryptamine analogues on the isolated rat stomach strip preparation. British Journal of Pharmacology and Chemotherapy. 14: 87-98. PMID 13651584 DOI: 10.1111/J.1476-5381.1959.TB00933.X  0.303
2000 MARLEY E, VANE JR. The distribution of methylpentynol and of methylpentynol carbamate in tissues and body fluids of cats. British Journal of Pharmacology and Chemotherapy. 13: 364-71. PMID 13618537 DOI: 10.1111/J.1476-5381.1958.TB00222.X  0.26
2000 LAJTHA LG, VANE JR. Dependence of bone marrow cells on the liver for purine supply. Nature. 182: 191-2. PMID 13566239 DOI: 10.1038/182191A0  0.2
2000 VANE JR. A sensitive method for the assay of 5-hydroxytryptamine. British Journal of Pharmacology and Chemotherapy. 12: 344-9. PMID 13460242 DOI: 10.1111/j.1476-5381.1957.tb00146.x  0.268
2000 Vane JR, Warner TD. Nomenclature for cox-2 inhibitors Lancet. 356: 1373-1374. PMID 11052577 DOI: 10.1016/S0140-6736(00)02837-3  0.372
2000 Ballou LR, Botting RM, Goorha S, Zhang J, Vane JR. Nociception in cyclooxygenase isozyme-deficient mice Proceedings of the National Academy of Sciences of the United States of America. 97: 10272-10276. PMID 10954756 DOI: 10.1073/Pnas.180319297  0.345
1999 Warner TD, Giuliano F, Vojnovic I, Bukasa A, Mitchell JA, Vane JR. Nonsteroid drug selectivities for cyclo-oxygenase-1 rather than cyclo-oxygenase-2 are associated with human gastrointestinal toxicity: A full in vitro analysis Proceedings of the National Academy of Sciences of the United States of America. 96: 7563-7568. PMID 10377455 DOI: 10.1073/Pnas.96.13.7563  0.408
1999 Simmons DL, Botting RM, Robertson PM, Madsen ML, Vane JR. Induction of an acetaminophen-sensitive cyclooxygenase with reduced sensitivity to nonsteroid antiinflammatory drugs. Proceedings of the National Academy of Sciences of the United States of America. 96: 3275-80. PMID 10077674 DOI: 10.1073/Pnas.96.6.3275  0.432
1999 Vane JR, Botting RM. Anti-inflammatory drugs and their mechanism of action. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. S78-87. PMID 9831328 DOI: 10.1007/s000110050284  0.312
1999 Vane JR. COX-2 inhibitors: background knowledge for clinical use. Introduction. Inflammation Research : Official Journal of the European Histamine Research Society ... [Et Al.]. S77. PMID 9831327 DOI: 10.1007/S000110050283  0.225
1998 DAY M, VANE JR. An analysis of the direct and indirect actions of drugs on the isolated guinea-pig ileum. British Journal of Pharmacology and Chemotherapy. 20: 150-70. PMID 14025623 DOI: 10.1111/J.1476-5381.1963.TB01306.X  0.267
1998 GELDER MG, VANE JR. Interaction of the effects of tyramine, amphetamine and reserprine in man. Psychopharmacologia. 3: 231-41. PMID 13947046 DOI: 10.1007/BF00411364  0.203
1998 PATON WD, VANE JR. Analysis of he responses of the isolated stomach to electrical stimulation and to drugs. The Journal of Physiology. 165: 10-46. PMID 13941859 DOI: 10.1113/jphysiol.1963.sp007040  0.234
1998 VANE JR, COLLIER HO, CORNE SJ, MARLEY E, BRADLEY PB. Tryptamine receptors in the central nervous system. Nature. 191: 1068-9. PMID 13780152 DOI: 10.1038/1911068A0  0.188
1998 Vane JR, Bakhle YS, Botting RM. Cyclooxygenases 1 And 2 Annual Review of Pharmacology and Toxicology. 38: 97-120. PMID 9597150 DOI: 10.1146/Annurev.Pharmtox.38.1.97  0.411
1998 Vane JR, Botting RM. Mechanism of action of nonsteroidal anti-inflammatory drugs. The American Journal of Medicine. 104: 2S-8S; discussion 21. PMID 9572314 DOI: 10.1016/S0002-9343(97)00203-9  0.334
1998 Vane JR, Botting RM. Mechanism of action of anti-inflammatory drugs. Advances in Experimental Medicine and Biology. 433: 131-8. PMID 9561120 DOI: 10.1007/978-1-4899-1810-9_27  0.257
1997 Botting R, Vane J. Re-addressing relative selectivities. Trends in Pharmacological Sciences. 18: 312-3. PMID 9345848 DOI: 10.1016/S0165-6147(97)90654-4  0.193
1997 Vane JR, Botting RM. Mechanism of action of aspirin-like drugs. Seminars in Arthritis and Rheumatism. 26: 2-10. PMID 9219313 DOI: 10.1016/S0049-0172(97)80046-7  0.323
1997 Ferreira SH, Moncada S, Vane JR. Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. 1973. British Journal of Pharmacology. 120: 401-12; discussion 3. PMID 9142418 DOI: 10.1111/j.1476-5381.1997.tb06823.x  0.254
1997 Vane JR. The use of isolated organs for detecting active substances in the circulating blood. 1964. British Journal of Pharmacology. 120: 250-63; discussion 2. PMID 9142409 DOI: 10.1111/j.1476-5381.1997.tb06805.x  0.267
1997 Vane JR. A sensitive method for the assay of 5-hydroxytryptamine. 1957. British Journal of Pharmacology. 120: 142-7; discussion 14. PMID 9142402 DOI: 10.1111/j.1476-5381.1997.tb06791.x  0.201
1997 Thiemermann C, Bowes J, Myint FP, Vane JR. Inhibition of the activity of poly(ADP ribose) synthetase reduces ischemia-reperfusion injury in the heart and skeletal muscle Proceedings of the National Academy of Sciences of the United States of America. 94: 679-683. PMID 9012844 DOI: 10.1073/Pnas.94.2.679  0.389
1997 Higgs EA, Higgs GA, Moncada S, Vane JR. Prostacyclin (Pgi2) Inhibits The Formation Of Platelet Thrombi In Arterioles And Venules Of The Hamster Cheek Pouch British Journal of Pharmacology. 63: 535-539. PMID 352466 DOI: 10.1111/J.1476-5381.1978.Tb07809.X  0.468
1997 Ferreira S, Moncada S, Vane J. Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs British Journal of Pharmacology. 120: 399-400. DOI: 10.1111/j.1476-5381.1997.tb06822.x  0.254
1997 Vane J. The use of isolated organs for detecting active substances in the circulating blood British Journal of Pharmacology. 120: 248-249. DOI: 10.1111/j.1476-5381.1997.tb06804.x  0.267
1997 Vane J, Vane J. A sensitive method for the assay of 5-hydroxytryptamine British Journal of Pharmacology. 120: 140-141. DOI: 10.1111/j.1476-5381.1997.tb06790.x  0.201
1997 Heneka MT, Ruetten H, Millar C, Thiemermann C, Vane JR. EFFECTS OF IBUPROFEN ON INDUCIBLE NITRIC OXIDE SYNTHASE, HAEMODYNAMICS AND ORGAN DYSFUNCTION IN A RAT MODEL OF SEPTIC SHOCK Shock. 7: 166. DOI: 10.1097/00024382-199703001-00676  0.293
1996 VANE JR. THE USE OF ISOLATED ORGANS FOR DETECTING ACTIVE SUBSTANCES IN THE CIRCULATING BLOOD. British Journal of Pharmacology and Chemotherapy. 23: 360-73. PMID 14228136 DOI: 10.1111/j.1476-5381.1964.tb01592.x  0.342
1996 REGOLI D, VANE JR. A SENSITIVE METHOD FOR THE ASSAY OF ANGIOTENSIN. British Journal of Pharmacology and Chemotherapy. 23: 351-9. PMID 14228135 DOI: 10.1111/J.1476-5381.1964.TB01591.X  0.286
1996 ARMITAGE AK, VANE JR. A SENSITIVE METHOD FOR THE ASSAY OF CATECHOL AMINES. British Journal of Pharmacology and Chemotherapy. 22: 204-10. PMID 14126052 DOI: 10.1111/J.1476-5381.1964.TB01560.X  0.259
1996 Benjamin N, Vane J. Nitric oxide and hypertension. Circulation. 94: 1197-8. PMID 8822966 DOI: 10.1161/01.CIR.94.6.1197  0.255
1996 Ruetten H, Thiemermann C, Vane JR. Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat. British Journal of Pharmacology. 118: 198-204. PMID 8733596 DOI: 10.1111/J.1476-5381.1996.Tb15386.X  0.412
1996 Vane JR. Introduction: mechanism of action of NSAIDs. British Journal of Rheumatology. 1-3. PMID 8630629 DOI: 10.1093/RHEUMATOLOGY/35.SUPPL_1.1  0.233
1996 Vane JR, Botting RM. Mechanism of action of anti-inflammatory drugs. Scandinavian Journal of Rheumatology. Supplement. 102: 9-21. PMID 8628981 DOI: 10.3109/03009749609097226  0.328
1996 Vane J. Meloxicam: A Viewpoint Drugs. 51: 431. DOI: 10.2165/00003495-199651030-00008  0.3
1996 Ruetten H, Thiemermann C, Vane J. Effects of the endothelin receptor antagonist, SB 209670, on circulatory failure and organ injury in endotoxic shock in the anaesthetized rat Resuscitation. 33: 92. DOI: 10.1016/0300-9572(96)89052-6  0.35
1995 Hohlfeld T, Klemm P, Thiemermann C, Warner TD, Schror K, Vane JR. The contribution of tumour necrosis factor-α and endothelin-1 to the increase of coronary resistance in hearts from rats treated with endotoxin British Journal of Pharmacology. 116: 3309-3315. PMID 8719812 DOI: 10.1111/J.1476-5381.1995.Tb15140.X  0.426
1995 Kimpe SJD, Thiemermann C, Vane JR. Role for intracellular platelet-activating factor in the circulatory failure in a model of Gram-positive shock British Journal of Pharmacology. 116: 3191-3198. PMID 8719795 DOI: 10.1111/J.1476-5381.1995.Tb15123.X  0.468
1995 Thiemermann C, Ruetten H, Wu C, Vane JR. The multiple organ dysfunction syndrome caused by endotoxin in the rat: attenuation of liver dysfunction by inhibitors of nitric oxide synthase British Journal of Pharmacology. 116: 2845-2851. PMID 8680715 DOI: 10.1111/J.1476-5381.1995.Tb15935.X  0.431
1995 Allcock GH, Warner TD, Vane JR. Roles of endothelin receptors in the regional and systemic vascular responses to ET‐1 in the anaesthetized ganglion‐blocked rat: use of selective antagonists British Journal of Pharmacology. 116: 2482-2486. PMID 8581288 DOI: 10.1111/J.1476-5381.1995.Tb15099.X  0.416
1995 Hide EJ, Ney P, Piper J, Thiemermann C, Vane JR. Reduction by prostaglandin E1 or prostaglandin E0 of myocardial infarct size in the rabbit by activation of ATP‐sensitive potassium channels British Journal of Pharmacology. 116: 2435-2440. PMID 8581281 DOI: 10.1111/J.1476-5381.1995.Tb15092.X  0.377
1995 Hattori Y, Szabó C, Gross SS, Thiemermann C, Vane JR. Lipid A and the lipid A analogue anti-tumour compound ONO-4007 induce nitric oxide synthese in vitro and in vivo European Journal of Pharmacology: Molecular Pharmacology. 291: 83-90. PMID 8566179 DOI: 10.1016/0922-4106(95)90128-0  0.297
1995 Battistini B, Brown M, Vane JR. Selective proteolitic activation and degradation of ETs and big ETs in parenchymal strips of the guinea-pig lung. Biochemical and Biophysical Research Communications. 207: 675-681. PMID 7864859 DOI: 10.1006/Bbrc.1995.1240  0.277
1995 Corder R, Vane JR. Radioimmunoassay evidence that the pressor effect of big endothelindash1 is due to local conversion to endothelindash1 Biochemical Pharmacology. 49: 375-380. PMID 7857324 DOI: 10.1016/0006-2952(94)00425-L  0.387
1995 Vane JR, Botting RM. Pharmacodynamic profile of prostacyclin American Journal of Cardiology. 75. PMID 7840052 DOI: 10.1016/S0002-9149(99)80377-4  0.447
1995 Akarasereenont P, Hide E, Ney P, Thiemermann C, Vane JR. The induction of cyclooxygenase-2 elicited by endotoxin in endothelial cells and macrophages is inhibited by prostaglandin E1 and 13,14-dihydro prostaglandin E1. Agents and Actions. Supplements. 45: 59-64. PMID 7717202 DOI: 10.1007/978-3-0348-7346-8_9  0.336
1995 Klemm P, Warner TD, Hohlfeld T, Corder R, Vane JR. Endothelin 1 mediates ex vivo coronary vasoconstriction caused by exogenous and endogenous cytokines Proceedings of the National Academy of Sciences of the United States of America. 92: 2691-2695. PMID 7708707 DOI: 10.1073/Pnas.92.7.2691  0.404
1995 Vane JR, Botting RM. New insights into the mode of action of anti-inflammatory drugs Inflammation Research. 44: 1-10. PMID 7664022 DOI: 10.1007/Bf01630479  0.392
1995 Battistini B, Woods M, O'Donnell LJD, Warner TD, Corder R, Fournier A, Farthing MJG, Vane JR. Contractile activity of endothelin precursors in the isolated gallbladder of the guinea-pig: presence of an endothelin-converting enzyme British Journal of Pharmacology. 114: 1383-1390. PMID 7606342 DOI: 10.1111/J.1476-5381.1995.Tb13359.X  0.39
1995 Klemm P, Warner TD, Willis D, Moore AR, Vane JR. Coronary vasoconstriction in vitro in the hearts of polyarthritic rats: effectiveness of in vivo treatment with the endothelin receptor antagonist SB 209670. British Journal of Pharmacology. 114: 1327-8. PMID 7606336 DOI: 10.1111/J.1476-5381.1995.Tb13351.X  0.406
1995 Harrison VJ, Barnes K, Turner AJ, Wood E, Corder R, Vane JR. Identification of endothelin 1 and big endothelin 1 in secretory vesicles isolated from bovine aortic endothelial cells Proceedings of the National Academy of Sciences of the United States of America. 92: 6344-6348. PMID 7603993 DOI: 10.1073/Pnas.92.14.6344  0.381
1995 Akarasereenont P, Bakhle YS, Thiemermann C, Vane JR. Cytokine-mediated induction of cyclo-oxygenase-2 by activation of tyrosine kinase in bovine endothelial cells stimulated by bacterial lipopolysaccharide. British Journal of Pharmacology. 115: 401-408. PMID 7582449 DOI: 10.1111/J.1476-5381.1995.Tb16347.X  0.374
1995 Vane J. Trumping the ACE The Lancet. 346: 916. PMID 7564719 DOI: 10.1016/S0140-6736(95)92770-0  0.315
1995 De Kimpe SJ, Hunter ML, Bryant CE, Thiemermann C, Vane JR. Delayed circulatory failure due to the induction of nitric oxide synthase by lipoteichoic acid from Staphylococcus aureus in anaesthetized rats. British Journal of Pharmacology. 114: 1317-23. PMID 7542534 DOI: 10.1111/J.1476-5381.1995.Tb13349.X  0.435
1995 Wu C, Thiemermann C, Vane JR. Glibenclamide‐induced inhibition of the expression of inducible nitric oxide synthase in cultured macrophages and in the anaesthetized rat British Journal of Pharmacology. 114: 1273-1281. PMID 7542532 DOI: 10.1111/J.1476-5381.1995.Tb13343.X  0.43
1995 Swierkosz TA, Mitchell JA, Warner TD, Botting RM, Vane JR. Co-induction of nitric oxide synthase and cyclo-oxygenase: Interactions between nitric oxide and prostanoids British Journal of Pharmacology. 114: 1335-1342. PMID 7541688 DOI: 10.1111/J.1476-5381.1995.Tb13353.X  0.459
1995 Wu C, Chen S, Szabó C, Thiemermann C, Vane JR. Aminoguanidine attenuates the delayed circulatory failure and improves survival in rodent models of endotoxic shock British Journal of Pharmacology. 114: 1666-1672. PMID 7541282 DOI: 10.1111/J.1476-5381.1995.Tb14955.X  0.407
1995 Akarasereenont P, Mitchell JA, Bakhle YS, Thiemermann C, Vane JR. Comparison of the induction of cyclooxygenase and nitric oxide synthase by endotoxin in endothelial cells and macrophages European Journal of Pharmacology. 273: 121-128. PMID 7537677 DOI: 10.1016/0014-2999(94)00680-6  0.441
1995 Wu C, Croxtall JD, Perretti M, Bryant CE, Thiemermann C, Flower RJ, Vane JR. Lipocortin 1 mediates the inhibition by dexamethasone of the induction by endotoxin of nitric oxide synthase in the rat Proceedings of the National Academy of Sciences of the United States of America. 92: 3473-3477. PMID 7536934 DOI: 10.1073/Pnas.92.8.3473  0.436
1995 Kimpe SJD, Kengatharan M, Thiemermann C, Vane JR. The cell wall components peptidoglycan and lipoteichoic acid from Staphylococcus aureus act in synergy to cause shock and multiple organ failure Proceedings of the National Academy of Sciences of the United States of America. 92: 10359-10363. PMID 7479784 DOI: 10.1073/Pnas.92.22.10359  0.424
1995 Swierkosz TA, Warner TD, Vane JR. NG-Hydroxy-L-Arginine Releases from Endothelial Cells Nitric Oxide which Increases cGMP in RFL-6 Fibroblasts Endothelium. 3: 121-129. DOI: 10.3109/10623329509053388  0.457
1995 Thiemermann C, Rütten H, Wu C-, Vane JR. 113 NITRIC OXIDE AND MULTIPLE ORGAN FAILURE Shock. 3: 35. DOI: 10.1097/00024382-199505000-00114  0.232
1995 Wellings RP, Corder R, Vane JR. Lack of effect of ET antibody or SB 209670 on endotoxin-induced renal failure. Journal of Cardiovascular Pharmacology. 25. DOI: 10.1097/00005344-199506263-00140  0.394
1995 Kengatharan M, Battistini B, Warner TD, Thiemermann C, Vane JR. Endothelin-1 mediates the increase in ex vivo coronary vascular resistance induced by hemorrhagic shock in the anesthetized rat. Journal of Cardiovascular Pharmacology. 25. DOI: 10.1097/00005344-199506263-00124  0.421
1995 Klemm P, Warner TD, Corder R, Vane JR. Endothelin-1 mediates coronary vasoconstriction caused by exogenous and endogenous cytokines. Journal of Cardiovascular Pharmacology. 25. DOI: 10.1097/00005344-199506263-00123  0.425
1995 Corder R, Carrier M, Khan N, Klemm P, Vane JR. Cytokine regulation of endothelin-1 release from bovine aortic endothelial cells Journal of Cardiovascular Pharmacology. 25. DOI: 10.1097/00005344-199506263-00018  0.401
1995 Vane JR, Botting R, Vanhoutte PM. Up-to-date on endothelins Journal of Cardiovascular Pharmacology. 26. DOI: 10.1097/00005344-199506263-00001  0.351
1995 Bennett A, Tavares I, Vane J. NSAIDs, Cox-2 inhibitors, and the gut The Lancet. 346: 1105-1106. DOI: 10.1016/S0140-6736(95)91782-9  0.271
1995 Bakhle YS, Akarasereenont PA, Thiemermann C, Vane JR. Tyrosine kinase is essential for induction of COX-2 in endothelial cells by LPS or inflammatory cytokines Pharmacological Research. 31: 312. DOI: 10.1016/1043-6618(95)87506-9  0.384
1995 Kimpe SJD, Thiemermann C, Vane JR. Intracellular release of PAF contributes to the induction of nitric oxide synthase in a model of gram-positive shock Pharmacological Research. 31: 305. DOI: 10.1016/1043-6618(95)87480-1  0.393
1995 Hide E, Piper J, Nev P, Thiemermann C, Vane JR. Cardioprotective effects of prostaglandin E1 in the rabbit are abolished by a blocker of ATP-sensitive potassium channels Pharmacological Research. 31: 78. DOI: 10.1016/1043-6618(95)86570-5  0.342
1995 Kengatharan M, Kimpe SJD, Thiemermann C, Vane JR. Role of tyrosine kinase and NFκB in the induction of nitric oxide synthase by lipoteichoic acid in cultured murine macrophages Pharmacological Research. 31: 65. DOI: 10.1016/1043-6618(95)86521-7  0.37
1995 Woods M, O’Donnell LJD, Battistini B, Warner T, Vane J, Fartming MG, Yaqoob J, Wu JJ, Norris LA, Khan MI, Keeling PWN, Maguire D, O’Sullivan G, Harvey B, Curran B, et al. Irish Society of Gastroenterology Irish Journal of Medical Science. 164: 245-256. DOI: 10.1007/Bf02967835  0.171
1994 Pistelli A, Mollace V, Nistico G, Salvemini D, Vane J. Nitroblue tetrazolium inhibits oxidation of glyceryl trinitrate to nitric oxide in bovine aortic smooth muscle cells Biochemical Pharmacology. 47: 1737-1742. PMID 8204090 DOI: 10.1016/0006-2952(94)90300-X  0.623
1994 Macarthur H, Warner TD, Wood EG, Corder R, Vane JR. Endothelin-1 Release from Endothelial Cells in Culture Is Elevated Both Acutely and Chronically by Short Periods of Mechanical Stretch Biochemical and Biophysical Research Communications. 200: 395-400. PMID 8166711 DOI: 10.1006/Bbrc.1994.1462  0.435
1994 Battistini B, Warner TD, Fournier A, Vane JR. Comparison of PD 145065 and Ro 46-2005 as antagonists of contractions of guinea-pig airways induced by endothelin-1 or IRL 1620 European Journal of Pharmacology. 252: 341-345. PMID 8162956 DOI: 10.1016/0014-2999(94)90184-8  0.293
1994 Vane JR. The Croonian Lecture, 1993: The Endothelium: Maestro of the Blood Circulation Philosophical Transactions of the Royal Society B. 343: 225-246. PMID 8146236 DOI: 10.1098/Rstb.1994.0023  0.403
1994 Vane J. Towards a better aspirin Nature. 367: 215-216. PMID 8121485 DOI: 10.1038/367215A0  0.356
1994 Wellings RP, Corder R, Doherty AM, Vane JR. Antagonism of renal and systemic responses to endothelin-1 infusion with PD 145065. European Journal of Pharmacology. 256: 201-4. PMID 8050471 DOI: 10.1016/0014-2999(94)90246-1  0.309
1994 McMurdo L, Thiemermann C, Vane JR. The effects of the endothelin ETA receptor antagonist, FR 139317, on infarct size in a rabbit model of acute myocardial ischaemia and reperfusion British Journal of Pharmacology. 112: 75-80. PMID 8032665 DOI: 10.1111/J.1476-5381.1994.Tb13032.X  0.39
1994 Warner TD, Allcock GH, Vane JR. Reversal of established responses to endothelin-1 in vivo and in vitro by the endothelin recptor antagonists, BQ-123 and PD 145065 British Journal of Pharmacology. 112: 207-213. PMID 8032643 DOI: 10.1111/j.1476-5381.1994.tb13053.x  0.292
1994 Battistini B, Warner TD, Fournier A, Vane JR. Characterization of ET(B) receptors mediating contractions induced by endothelin-1 or IRL 1620 in guinea-pig isolated airways: Effects of BQ-123, FR139317 or PD 145065 British Journal of Pharmacology. 111: 1009-1116. PMID 8032583 DOI: 10.1111/J.1476-5381.1994.Tb14844.X  0.276
1994 Desai KM, Warner TD, Vane JR. 5-HT3 receptors do not mediate vagally-induced relaxation or contraction of the isolated stomach of the guinea-pig British Journal of Pharmacology. 111: 346-350. PMID 8012716 DOI: 10.1111/j.1476-5381.1994.tb14066.x  0.291
1994 Wellings RP, Corder R, Warner TD, Cristol JP, Thiemermann C, Vane JR. Evidence from receptor antagonists of an important role for ET(B) receptor-mediated vasoconstrictor effects of endothelin-1 in the rat kidney British Journal of Pharmacology. 111: 515-520. PMID 8004396 DOI: 10.1111/j.1476-5381.1994.tb14767.x  0.311
1994 McMurdo L, Thiemermann C, Vane JR. The endothelin ETB receptor agonist, IRL 1620, causes vasodilation and inhibits ex vivo platelet aggregation in the anaesthetised rabbit European Journal of Pharmacology. 259: 51-55. PMID 7957593 DOI: 10.1016/0014-2999(94)90156-2  0.464
1994 Battistini B, O'Donnell LJD, Warner TD, Fournier A, Farthing MJG, Vane JR. Characterization of endothelin (ET) receptors in the isolated gall bladder of the guinea‐pig: evidence for an additional ET receptor subtype British Journal of Pharmacology. 112: 1244-1250. PMID 7952887 DOI: 10.1111/J.1476-5381.1994.Tb13217.X  0.255
1994 Wu CC, Szabó C, Chen SJ, Thiemermann C, Vane JR. Activation of soluble guanylyl cyclase by a factor other than nitric oxide or carbon monoxide contributes to the vascular hyporeactivity to vasoconstrictor agents in the aorta of rats treated with endotoxin. Biochemical and Biophysical Research Communications. 201: 436-42. PMID 7911015 DOI: 10.1006/BBRC.1994.1720  0.366
1994 Mitchell JA, Belvisi MG, Akarasereenont P, Robbins RA, Kwon O‐, Croxtall JJ, Barnes PJ, Vane JR. Induction of cyclo‐oxygenase‐2 by cytokines in human pulmonary epithelial cells: regulation by dexamethasone British Journal of Pharmacology. 113: 1008-1014. PMID 7858842 DOI: 10.1111/J.1476-5381.1994.Tb17093.X  0.412
1994 Akarasereenont P, Mitchell JA, Appleton I, Thiemermann C, Vane JR. Involvement of tyrosine kinase in the induction of cyclo‐oxygenase and nitric oxide synthase by endotoxin in cultured cells British Journal of Pharmacology. 113: 1522-1528. PMID 7534189 DOI: 10.1111/J.1476-5381.1994.Tb17169.X  0.435
1994 Desai KM, Warner TD, Bishop AE, Polak JM, Vane JR. Nitric oxide, and not vasoactive intestinal peptide, as the main neurotransmitter of vagally induced relaxation of the guinea pig stomach British Journal of Pharmacology. 113: 1197-1202. PMID 7534182 DOI: 10.1111/J.1476-5381.1994.Tb17124.X  0.425
1994 Szabó C, Southan GJ, Thiemermann C, Vane JR. The mechanism of the inhibitory effect of polyamines on the induction of nitric oxide synthase: role of aldehyde metabolites. British Journal of Pharmacology. 113: 757-766. PMID 7532082 DOI: 10.1111/J.1476-5381.1994.Tb17058.X  0.476
1994 Szabó C, Southan GJ, Wood E, Thiemermann C, Vane JR. Inhibition by spermine of the induction of nitric oxide synthase in J774.2 macrophages : requirement of a serum factor British Journal of Pharmacology. 112: 355-356. PMID 7521253 DOI: 10.1111/J.1476-5381.1994.Tb13078.X  0.438
1994 Korbut I, Warner TD, Gryglewski RJ, Vane JR. The effect of nitric oxide synthase inhibition on the plasma fibrinolytic system in septic shock in rats British Journal of Pharmacology. 112: 289-291. PMID 7518306 DOI: 10.1111/J.1476-5381.1994.Tb13066.X  0.464
1994 Wood PJ, Sansom JM, Stratford IJ, Adams GE, Szabo C, Thiemermann C, Vane JR. Modification of metabolism of transplantable and spontaneous murine tumors by the nitric oxide synthase inhibitor, nitro-L-arginine. International Journal of Radiation Oncology, Biology, Physics. 29: 443-7. PMID 7516319 DOI: 10.1016/0360-3016(94)90435-9  0.273
1994 Vane JR, Mitchell JA, Appleton I, Tomlinson A, Bishop-Bailey D, Croxtall J, Willoughby DA. Inducible isoforms of cyclooxygenase and nitric-oxide synthase in inflammation. Proceedings of the National Academy of Sciences of the United States of America. 91: 2046-50. PMID 7510883 DOI: 10.1073/Pnas.91.6.2046  0.308
1994 Szabo C, Thiemermann C, Wu CC, Perretti M, Vane JR. Attenuation of the induction of nitric oxide synthase by endogenous glucocorticoids accounts for endotoxin tolerance in vivo Proceedings of the National Academy of Sciences of the United States of America. 91: 271-275. PMID 7506416 DOI: 10.1073/Pnas.91.1.271  0.319
1993 Wood PJ, Stratford IJ, Adams GE, Szabo C, Thiemermann C, Vane JR. Modification of energy metabolism and radiation response of a murine tumour by changes in nitric oxide availability. Biochemical and Biophysical Research Communications. 192: 505-10. PMID 8484762 DOI: 10.1006/Bbrc.1993.1444  0.389
1993 Cristol JP, Warner TD, Thiemermann C, Vane JR. Mediation via different receptors of the vasoconstrictor effects of endothelins and sarafotoxins in the systemic circulation and renal vasculature of the anaesthetized rat British Journal of Pharmacology. 108: 776-779. PMID 8467364 DOI: 10.1111/j.1476-5381.1993.tb12877.x  0.293
1993 Warner TD, Vane JR. ET touches down in Houston Nature. 362: 497-498. PMID 8464486 DOI: 10.1038/362497A0  0.232
1993 McMurdo L, Corder R, Thiemermann C, Vane JR. Incomplete inhibition of the pressor effects of endothelin-1 and related peptides in the anaesthetized rat with BQ-123 provides evidence for more than one vasoconstrictor receptor. British Journal of Pharmacology. 108: 557-61. PMID 8448603 DOI: 10.1111/j.1476-5381.1993.tb12840.x  0.31
1993 Macarthur H, Hecker M, Busse R, Vane JR. Selective inhibition of agonist‐induced but not shear stress‐dependent release of endothelial autacoids by thapsigargin British Journal of Pharmacology. 108: 100-105. PMID 8428199 DOI: 10.1111/J.1476-5381.1993.Tb13446.X  0.336
1993 Salvemini D, Pistelli A, Vane J. Conversion of glyceryl trinitrate to nitric oxide in tolerant and non-tolerant smooth muscle and endothelial cells British Journal of Pharmacology. 108: 162-169. PMID 8381319 DOI: 10.1111/J.1476-5381.1993.Tb13457.X  0.586
1993 McMurdo L, Lidbury PS, Thiemermann C, Vane JR. Mediation of endothelin-1-induced inhibition of platelet aggregation via the ETB receptor. British Journal of Pharmacology. 109: 530-534. PMID 8358553 DOI: 10.1111/J.1476-5381.1993.Tb13602.X  0.446
1993 Vane J. Control of the Circulation by Endothelial Mediators International Archives of Allergy and Immunology. 101: 333-345. PMID 8353456 DOI: 10.1159/000236474  0.372
1993 Mitchell JA, Akarasereenont P, Thiemermann C, Flower RJ, Vane JR. Selectivity of nonsteroidal antiinflammatory drugs as inhibitors of constitutive and inducible cyclooxygenase Proceedings of the National Academy of Sciences of the United States of America. 90: 11693-11697. PMID 8265610 DOI: 10.1073/Pnas.90.24.11693  0.432
1993 Warner TD, Allcock GH, Mickley EJ, Vane JR. Characterization of endothelin receptors mediating the effects of the endothelin/sarafotoxin peptides on autonomic neurotransmission in the rat vas deferens and guinea-pig ileum British Journal of Pharmacology. 110: 783-789. PMID 8242252 DOI: 10.1111/j.1476-5381.1993.tb13880.x  0.288
1993 Warner TD, Allcock GH, Corder R, Vane JR. Use of the endothelin antagonists BQ-123 and PD 142893 to reveal three endothelin receptors mediating smooth muscle contraction and the release of EDRF British Journal of Pharmacology. 110: 777-782. PMID 8242251 DOI: 10.1111/j.1476-5381.1993.tb13879.x  0.305
1993 Lidbury PS, Cirillo R, Vane JR. Dissociation of the anti-ischaemic effects of cloricromene from its anti-platelet activity. British Journal of Pharmacology. 110: 275-80. PMID 8220889 DOI: 10.1111/J.1476-5381.1993.Tb13805.X  0.476
1993 Warner TD, Battistini B, Allcock GH, Vane JR. Endothelin ETA and ETB receptors mediate vasoconstriction and prostanoid release in the isolated kidney of the rat European Journal of Pharmacology. 250: 447-453. PMID 8112405 DOI: 10.1016/0014-2999(93)90032-D  0.316
1993 Szabo C, Thiemermann C, Vane JR. Dihydropyridine Antagonists and Agonists of Calcium Channels Inhibit the Induction of Nitric Oxide Synthase by Endotoxin in Cultured Macrophages Biochemical and Biophysical Research Communications. 196: 825-830. PMID 7694580 DOI: 10.1006/Bbrc.1993.2323  0.316
1993 Szabo C, Thiemermann C, Vane JR. Inhibition of the Production of Nitric Oxide and Vasodilator Prostaglandins Attenuates the Cardiovascular Response to Bacterial Endotoxin in Adrenalectomized Rats Proceedings of the Royal Society B: Biological Sciences. 253: 233-238. PMID 7694300 DOI: 10.1098/Rspb.1993.0108  0.359
1993 Szabó C, Wu CC, Mitchell JA, Gross SS, Thiemermann C, Vane JR. Platelet-activating factor contributes to the induction of nitric oxide synthase by bacterial lipopolysaccharide Circulation Research. 73: 991-999. PMID 7693362 DOI: 10.1161/01.Res.73.6.991  0.381
1993 Thiemermann C, Wu C‐, Szabó C, Perretti M, Vane JR. Role of tumour necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock British Journal of Pharmacology. 110: 177-182. PMID 7693276 DOI: 10.1111/J.1476-5381.1993.Tb13789.X  0.324
1993 Mitchell JA, Kohlhaas KL, Sorrentino R, Warner TD, Murad F, Vane JR. Induction by endotoxin of nitric oxide synthase in the rat mesentery: Lack of effect on action of vasoconstrictors British Journal of Pharmacology. 109: 265-270. PMID 7684306 DOI: 10.1111/J.1476-5381.1993.Tb13563.X  0.435
1993 Cristol JP, Thiemermann C, Mitchell JA, Walder C, Vane JR. Support of renal blood flow after ischaemic-reperfusion injury by endogenous formation of nitric oxide and of cyclo-oxygenase vasodilator metabolites. British Journal of Pharmacology. 109: 188-94. PMID 7684301 DOI: 10.1111/J.1476-5381.1993.Tb13552.X  0.406
1993 Szabó C, Mitchell JA, Thiemermann C, Vane JR. Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. British Journal of Pharmacology. 108: 786-792. PMID 7682137 DOI: 10.1111/J.1476-5381.1993.Tb12879.X  0.362
1993 Thiemermann C, Szabo C, Mitchell JA, Vane JR. Vascular hyporeactivity to vasoconstrictor agents and hemodynamic decompensation in hemorrhagic shock is mediated by nitric oxide Proceedings of the National Academy of Sciences of the United States of America. 90: 267-271. PMID 7678341 DOI: 10.1073/Pnas.90.1.267  0.393
1993 Corder R, Harrison VJ, Khan N, Änggård EE, Vane JR. Effects of phosphoramidon in endothelial cell cultures on the endogenous synthesis of endothelin-1 and on conversion of exogenous big endothelin-1 to endothelin-1. Journal of Cardiovascular Pharmacology. 22. PMID 7510004 DOI: 10.1097/00005344-199322008-00021  0.429
1993 Kaw S, Warner TD, Vane JR. The metabolism of endothelin-1 and big endothelin-1 by the isolated perfused kidney of the rabbit Journal of Cardiovascular Pharmacology. 22. PMID 7510001 DOI: 10.1097/00005344-199322008-00019  0.42
1993 Harrison VJ, Corder R, Änggård EE, Vane JR. Evidence for vesicles that transport endothelin-1 in bovine aortic endothelial cells. Journal of Cardiovascular Pharmacology. 22. PMID 7509999 DOI: 10.1097/00005344-199322008-00017  0.387
1993 Corder R, Khan N, Änggård EE, Vane JR. Calcium ionophores inhibit the release of endothelin-1 from endothelial cells. Journal of Cardiovascular Pharmacology. 22. PMID 7509995 DOI: 10.1097/00005344-199322008-00013  0.438
1993 McMurdo L, Lidbury PS, Corder R, Thiemermann C, Vane JR. Heterogeneous receptors mediate endothelin-1-induced changes in blood pressure, hematocrit, and platelet aggregation. Journal of Cardiovascular Pharmacology. 22. PMID 7509940 DOI: 10.1097/00005344-199322008-00050  0.433
1993 Warner TD, Allcock GH, Mickley EJ, Corder R, Vane JR. Comparative studies with the endothelin receptor antagonists BQ-123 and PD 142893 indicate at least three endothelin receptors Journal of Cardiovascular Pharmacology. 22. PMID 7509920 DOI: 10.1097/00005344-199322008-00032  0.391
1993 Wellings RP, Warner TD, Thiemermann C, Cristol JP, Corder R, Vane JR. Vasoconstriction in the rat kidney induced by endothelin-1 is blocked by PD 145065 Journal of Cardiovascular Pharmacology. 22. PMID 7509915 DOI: 10.1097/00005344-199322008-00028  0.408
1993 Szabó C, Wu CC, Gross SS, Thiemermann C, Vane JR. Interleukin-1 contributes to the induction of nitric oxide synthase by endotoxin in vivo European Journal of Pharmacology. 250: 157-160. PMID 7509750 DOI: 10.1016/0014-2999(93)90634-T  0.309
1993 Gross SS, Levi R, Madera A, Kwan Ha Park, Vane J, Hattori Y. Tetrahydrobiopterin synthesis is induced by LPS in vascular smooth muscle and is rate-limiting for nitric oxide production Advances in Experimental Medicine and Biology. 338: 295-300. PMID 7508166 DOI: 10.1007/978-1-4615-2960-6_61  0.317
1993 Khatsenko OG, Gross SS, Rifland AB, Vane JR. Nitric oxide is a mediator of the decrease in cytochrome P450-dependent metabolism caused by immunostimulants Proceedings of the National Academy of Sciences of the United States of America. 90: 11147-11151. PMID 7504296 DOI: 10.1073/Pnas.90.23.11147  0.407
1993 Zembowicz A, Chłopicki S, Radziszewski W, Vane JR, Gryglewski RJ. NG-hydroxy-L-arginine and hydroxyguanidine potentiate the biological activity of endothelium-derived relaxing factor released from the rabbit aorta. Biochemical and Biophysical Research Communications. 189: 711-6. PMID 1472042 DOI: 10.1016/0006-291X(92)92259-Z  0.34
1993 Zembowicz A, Swierkosz TA, Southan GJ, Hecker M, Vane JR. Potentiation of the vasorelaxant activity of nitric oxide by hydroxyguanidine: implications for the nature of endothelium-derived relaxing factor. British Journal of Pharmacology. 107: 1001-7. PMID 1281716 DOI: 10.1111/j.1476-5381.1992.tb13398.x  0.358
1993 Kim DS, Kim KH, Yilmaz H, Roe JM, Morgan KL, Al-Laith M, Pearce FL, Bellavia A, Mattei M, Dieli F, Salerno A, Caroleo MC, Asherson GL, Colizzi V, Dueymes M, ... ... Vane J, et al. Contents, Vol. 101, 1993 International Archives of Allergy and Immunology. 101. DOI: 10.1159/000236473  0.29
1992 Sessa WC, Kaw S, Zembowicz A, Anggård E, Hecker M, Vane JR. Human polymorphonuclear leukocytes generate and degrade endothelin-1 by two distinct neutral proteases. Journal of Cardiovascular Pharmacology. S34-8. PMID 1725374 DOI: 10.1097/00005344-199100177-00010  0.421
1992 Withrington PG, Ansari N, Croxton R, Nucci GD, Vane JR. The actions of endothelins-1 and -3 on the vascular and capsular smooth muscle of the isolated blood perfused spleen of the dog. British Journal of Pharmacology. 105: 490-494. PMID 1559137 DOI: 10.1111/J.1476-5381.1992.Tb14281.X  0.402
1992 Hecker M, Siegle I, MacArthur H, Sessa WC, Vane JR. Role of intracellular thiols in release of EDRF from cultured endothelial cells American Journal of Physiology - Heart and Circulatory Physiology. 262. PMID 1558197 DOI: 10.1152/Ajpheart.1992.262.3.H888  0.462
1992 Sprague RS, Thiemermann C, Vane JR. Endogenous endothelium-derived relaxing factor opposes hypoxic pulmonary vasoconstriction and supports blood flow to hypoxic alveoli in anesthetized rabbits. Proceedings of the National Academy of Sciences of the United States of America. 89: 8711-5. PMID 1528883 DOI: 10.1073/Pnas.89.18.8711  0.425
1992 Kaw S, Hecker M, Vane JR. The two-step conversion of big endothelin 1 to endothelin 1 and degradation of endothelin 1 by subcellular fractions from human polymorphonuclear leukocytes. Proceedings of the National Academy of Sciences of the United States of America. 89: 6886-6890. PMID 1495979 DOI: 10.1073/Pnas.89.15.6886  0.416
1992 D'Orleans-Juste P, Mitchell JA, Wood EG, Hecker M, Vane JR. Comparison of the release of vasoactive factors from venous and arterial bovine cultured endothelial cells. Canadian Journal of Physiology and Pharmacology. 70: 687-694. PMID 1423010 DOI: 10.1139/Y92-088  0.457
1992 Walder CE, Thiemermann C, Vane JR. NG-hydroxy-L-arginine prevents the haemodynamic effects of nitric oxide synthesis inhibition in the anaesthetized rat. British Journal of Pharmacology. 107: 476-80. PMID 1422593 DOI: 10.1111/J.1476-5381.1992.Tb12770.X  0.404
1992 Salvemini D, Pistelli A, Mollace V, Änggård E, Vane J. The metabolism of glyceryl trinitrate to nitric oxide in the macrophage cell line J774 and its induction by Escherichia coli lipopolysaccharide Biochemical Pharmacology. 44: 17-24. PMID 1378739 DOI: 10.1016/0006-2952(92)90032-E  0.582
1992 Mitchell JA, De Nucci G, Warner TD, Vane JR. Different patterns of release of endothelium-derived relaxing factor and prostacyclin British Journal of Pharmacology. 105: 485-489. PMID 1373103 DOI: 10.1111/J.1476-5381.1992.Tb14280.X  0.436
1992 Zembowicz A, Vane JR. Induction of nitric oxide synthase activity by toxic shock syndrome toxin 1 in a macrophage-monocyte cell line. Proceedings of the National Academy of Sciences of the United States of America. 89: 2051-2055. PMID 1372433 DOI: 10.1073/Pnas.89.6.2051  0.469
1992 Salvemini D, Mollace V, Pistelli A, Anggard E, Vane J. Cultured astrocytoma cells generate a nitric oxide-like factor from endogenous L-arginine and glyceryl trinitrate: Effect of E. coli lipopolysaccharide British Journal of Pharmacology. 106: 931-936. PMID 1327394 DOI: 10.1111/J.1476-5381.1992.Tb14437.X  0.577
1992 Gryglewski RJ, Zembowicz A, Salvemini D, Taylor GW, Vane JR. Modulation of the pharmacological actions of nitrovasodilators by methylene blue and pyocyanin British Journal of Pharmacology. 106: 838-845. PMID 1327388 DOI: 10.1111/J.1476-5381.1992.Tb14422.X  0.617
1992 Salvemini D, Mollace V, Pistelli A, Anggard E, Vane J. Metabolism of glyceryl trinitrate to nitric oxide by endothelial cells and smooth muscle cells and its induction by Escherichia coli lipopolysaccharide Proceedings of the National Academy of Sciences of the United States of America. 89: 982-986. PMID 1310543 DOI: 10.1073/Pnas.89.3.982  0.579
1992 Zembowicz A, Swierkosz TA, Southan GJ, Hecker M, Gryglewski RJ, Vane JR. Mechanisms of the endothelium-dependent relaxation induced by NG-hydroxy-L-arginine. Journal of Cardiovascular Pharmacology. 20. PMID 1282987 DOI: 10.1097/00005344-199204002-00017  0.458
1992 Kaw S, Hecker M, Southan GJ, Warner TD, Vane JR. Characterization of serine protease-derived metabolites of big endothelin in the cytosolic fraction from human polymorphonuclear leukocytes Journal of Cardiovascular Pharmacology. 20. PMID 1282976 DOI: 10.1097/00005344-199204002-00008  0.408
1992 Hecker M, Walsh DT, Vane JR. Characterization of a microsomal calcium-dependent nitric oxide synthase in activated J774.2 monocyte/macrophages. Journal of Cardiovascular Pharmacology. 20: S139-41. PMID 1282950 DOI: 10.1097/00005344-199204002-00039  0.405
1992 Lüscher T, Masaki T, Mulvany M, Rubanyi G, Vane J, Vanhoutte P. 2nd International Symposium on Endothelium-Derived Vasoactive Factors (Part 2 of 11) Journal of Vascular Research. 29: 90-104. DOI: 10.1159/000317442  0.244
1992 Salvemini D, Pistelli A, Mollace V, Anggard E, Vane J. J774 Cells metabolise glyceryl trinitrate by an enzymic pathway which can be induced by E. colt lipopolysaccharide Pharmacological Research. 26: 229. DOI: 10.1016/1043-6618(92)91167-F  0.557
1991 Hecker M, Mitchell JA, Swierkosz TA, Sessa WC, Vane JR. Inhibition by L-glutamine of the release of endothelium-derived relaxing factor from cultured endothelial cells. British Journal of Pharmacology. 101: 237-9. PMID 2257431 DOI: 10.1111/J.1476-5381.1990.Tb12693.X  0.334
1991 Thiemermann C, Al-Damluji S, Hecker M, Vane JR. FMRF-amide and L-Arg-L-Phe increase blood pressure and heart rate in the anaesthetised rat by central stimulation of the sympathetic nervous system. Biochemical and Biophysical Research Communications. 175: 318-324. PMID 1998514 DOI: 10.1016/S0006-291X(05)81237-9  0.376
1991 Sessa WC, Kaw S, Hecker M, Vane JR. The biosynthesis of endothelin-1 by human polymorphonuclear leukocytes. Biochemical and Biophysical Research Communications. 174: 613-8. PMID 1993057 DOI: 10.1016/0006-291X(91)91461-K  0.357
1991 Vane JR, Botting RM. Heart disease, aspirin, and fish oil. Circulation. 84: 2588-2590. PMID 1959207 DOI: 10.1161/01.Cir.84.6.2588  0.306
1991 Vane J, O'Grady J. Clinical pharmacology in the pharmaceutical industry. British Journal of Clinical Pharmacology. 32: 155-7. PMID 1931465 DOI: 10.1111/J.1365-2125.1991.TB03875.X  0.177
1991 Mitchell JA, De Nucci G, Warner TD, Vane JR. Alkaline buffers release EDRF from bovine cultured aortic endothelial cells British Journal of Pharmacology. 103: 1295-1302. PMID 1884092 DOI: 10.1111/J.1476-5381.1991.Tb09783.X  0.446
1991 Walder CE, Thiemermann C, Vane JR. The involvement of endothelium-derived relaxing factor in the regulation of renal cortical blood flow in the rat. British Journal of Pharmacology. 102: 967-73. PMID 1855125 DOI: 10.1111/J.1476-5381.1991.Tb12285.X  0.432
1991 MacIntyre I, Zaidi M, Alam ASMT, Datta HK, Moonga BS, Lidbury PS, Hecker M, Vane JR. Osteoclastic inhibition: An action of nitric oxide not mediated by cyclic GMP Proceedings of the National Academy of Sciences of the United States of America. 88: 2936-2940. PMID 1849281 DOI: 10.1073/Pnas.88.7.2936  0.401
1991 Thiemermann C, Mustafa M, Mester PA, Mitchell JA, Hecker M, Vane JR. Inhibition of the release of endothelium‐derived relaxing factor in vitro and in vivo by dipeptides containing NG‐nitro‐l‐arginine British Journal of Pharmacology. 104: 31-38. PMID 1786515 DOI: 10.1111/J.1476-5381.1991.Tb12380.X  0.446
1991 Mollace V, Salvemini D, Vane J. Studies on the importance of the proposed release of nitric oxide from platelets Thrombosis Research. 65: 533-542. PMID 1725563 DOI: 10.1016/S0049-3848(05)80002-7  0.586
1991 Huneidi AH, Thiemermann C, Lidbury PS, D'Orléans-Juste P, Anggård EE, Afshar F, Vane JR. Endothelin-1 and big endothelin cause subarachnoid hemorrhage in the anesthetized rabbit. Journal of Cardiovascular Pharmacology. 17: S492-5. PMID 1725421 DOI: 10.1097/00005344-199100177-00140  0.386
1991 D'Orléans-Juste P, Lidbury PS, Telemaque S, Warner TD, Vane JR. Human big endothelin releases prostacyclin in vivo and in vitro through a phosphoramidon-sensitive conversion to endothelin-1 Journal of Cardiovascular Pharmacology. 17: S251-S255. PMID 1725347 DOI: 10.1097/00005344-199100177-00072  0.43
1991 Mollace V, Salvemini D, Anggard E, Vane J. Nitric oxide from vascular smooth muscle cells: Regulation of platelet reactivity and smooth muscle cell guanylate cyclase British Journal of Pharmacology. 104: 633-638. PMID 1724627 DOI: 10.1111/J.1476-5381.1991.Tb12481.X  0.597
1991 Hecker M, Walsh DT, Vane JR. On the substrate specificity of nitric oxide synthase. Febs Letters. 294: 221-4. PMID 1721880 DOI: 10.1016/0014-5793(91)81434-A  0.406
1991 Masini E, Salvemini D, Pistelli A, Mannaioni PF, Vane JR. Rat mast cells synthesize a nitric oxide like-factor which modulates the release of histamine Agents and Actions. 33: 61-63. PMID 1716838 DOI: 10.1007/Bf01993127  0.636
1991 Salvemini D, Radziszewski W, Mollace V, Moore A, Willoughby D, Vane J. Diphenylene iodonium, an inhibitor of free radical formation, inhibits platelet aggregation European Journal of Pharmacology. 199: 15-18. PMID 1716574 DOI: 10.1016/0014-2999(91)90631-Y  0.609
1991 Masini E, Mannaioni PF, Pistelli A, Salvemini D, Vane J. Impairment of the L-arginine-nitric oxide pathway in mast cells from spontaneously hypertensive rats Biochemical and Biophysical Research Communications. 177: 1178-1182. PMID 1711845 DOI: 10.1016/0006-291X(91)90664-S  0.593
1991 Desai KM, Zembowicz A, Sessa WC, Vane JR. Nitroxergic nerves mediate vagally induced relaxation in the isolated stomach of the guinea pig. Proceedings of the National Academy of Sciences of the United States of America. 88: 11490-4. PMID 1684865 DOI: 10.1073/Pnas.88.24.11490  0.449
1991 Desai KM, Sessa WC, Vane JR. Involvement of nitric oxide in the reflex relaxation of the stomach to accommodate food or fluid. Nature. 351: 477-9. PMID 1675430 DOI: 10.1038/351477A0  0.416
1991 Zembowicz A, Hecker M, Macarthur H, Sessa WC, Vane JR. Nitric oxide and another potent vasodilator are formed from NG-hydroxy-L-arginine by cultured endothelial cells Proceedings of the National Academy of Sciences of the United States of America. 88: 11172-11176. PMID 1662386 DOI: 10.1073/Pnas.88.24.11172  0.416
1991 Salvemini D, De Nucci G, Vane JR. Superoxide dismutase cooperates with prostacyclin to inhibit platelet aggregation: a comparative study in washed platelets and platelet rich plasma Thrombosis and Haemostasis. 65: 421-424. PMID 1647553  0.558
1991 Vane JR, Botting RM. Endothelium-derived vasoactive factors and the control of the circulation. Seminars in Perinatology. 15: 4-10. DOI: 10.5555/Uri:Pii:014600059190067Z  0.469
1991 Hecker M, Sessa WC, Mitchell JA, Änggård EE, Vane JR. The Biosynthesis of Endothelium-Derived Relaxing Factor by Endothelial Cells as a Means of Removing Excess Nitrogen Journal of Cardiovascular Pharmacology. 17: S19-S24. DOI: 10.1097/00005344-199117003-00005  0.416
1991 Salvemini D, Masini E, Pistelli A, Mannaioni PF, Vane J. Nitric Oxide: A Regulatory Mediator of Mast Cell Reactivity Journal of Cardiovascular Pharmacology. 17. DOI: 10.1097/00005344-199100001-00046  0.626
1991 Salvemini D, Masini E, Pistelli A, Mannaioni PF, Vane J. Nitric oxide: A regulatory mediator of mast cell reactivity Journal of Cardiovascular Pharmacology. 17.  0.615
1990 Kondo K, Mitchell JA, de Nucci G, Vane JR. Simultaneous measurement of endothelium-derived relaxing factor by bioassay and guanylate cyclase stimulation. British Journal of Pharmacology. 98: 630-6. PMID 2573403 DOI: 10.1111/j.1476-5381.1989.tb12637.x  0.359
1990 Fuxe K, Anggård E, Lundgren K, Cintra A, Agnati LF, Galton S, Vane J. Localization of [125I]endothelin-1 and [125I]endothelin-3 binding sites in the rat brain. Acta Physiologica Scandinavica. 137: 563-4. PMID 2557731 DOI: 10.1111/J.1748-1716.1989.TB08802.X  0.217
1990 Lidbury PS, Antunes E, de Nucci G, Vane JR. Interactions of iloprost and sodium nitroprusside on vascular smooth muscle and platelet aggregation. British Journal of Pharmacology. 98: 1275-80. PMID 2482103 DOI: 10.1111/j.1476-5381.1989.tb12674.x  0.377
1990 Hecker M, Mitchell JA, Harris HJ, Katsura M, Thiemermann C, Vane JR. Endothelial cells metabolize NG-monomethyl-L-arginine to L-citrulline and subsequently to L-arginine. Biochemical and Biophysical Research Communications. 167: 1037-43. PMID 2322257 DOI: 10.1016/0006-291X(90)90627-Y  0.39
1990 Mitchell JA, Hecker M, Vane JR. The generation of L-arginine in endothelial cells is linked to the release of endothelium-derived relaxing factor. European Journal of Pharmacology. 176: 253-254. PMID 2311672 DOI: 10.1016/0014-2999(90)90541-D  0.409
1990 Warner TD, D'Orleans-Juste P, Vane JR. Endothelin-1 and U46619 potentiate selectively the venous responses to nerve stimulation within the perfused superior mesenteric vascular bed of the rat Biochemical and Biophysical Research Communications. 172: 745-750. PMID 2241966 DOI: 10.1016/0006-291X(90)90737-8  0.288
1990 Mollace V, Salvemini D, Änggård E, Vane J. Cultured astrocytoma cells inhibit platelet aggregation by releasing a nitric oxide-like factor Biochemical and Biophysical Research Communications. 172: 564-569. PMID 2241954 DOI: 10.1016/0006-291X(90)90710-5  0.592
1990 Hecker M, Sessa WC, Harris HJ, Anggård EE, Vane JR. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: cultured endothelial cells recycle L-citrulline to L-arginine. Proceedings of the National Academy of Sciences of the United States of America. 87: 8612-6. PMID 2236071 DOI: 10.1073/Pnas.87.21.8612  0.404
1990 Thiemermann C, Vane J. Inhibition of nitric oxide synthesis reduces the hypotension induced by bacterial lipopolysaccharides in the rat in vivo. European Journal of Pharmacology. 182: 591-5. PMID 2226626 DOI: 10.1016/0014-2999(90)90062-B  0.358
1990 Mitchell JA, Hecker M, Ånggård EE, Vane JR. Cultured endothelial cells maintain their L-arginine level despite the continuous release of EDRF. European Journal of Pharmacology. 182: 573-576. PMID 2226624 DOI: 10.1016/0014-2999(90)90058-E  0.421
1990 Swierkosz TA, Mitchell JA, Sessa WC, Hecker M, Vane JR. L-glutamine inhibits the release of endothelium-derived relaxing factor from the rabbit aorta. Biochemical and Biophysical Research Communications. 172: 143-8. PMID 2222463 DOI: 10.1016/S0006-291X(05)80184-6  0.346
1990 Thiemermann C, May GR, Page CP, Vane JR. Endothelin-1 inhibits platelet aggregation in vivo: a study with 111indium-labelled platelets. British Journal of Pharmacology. 99: 303-8. PMID 2183912 DOI: 10.1111/J.1476-5381.1990.Tb14699.X  0.463
1990 Salvemini D, Korbut R, Änggård E, Vane J. Immediate release of a nitric oxide-like factor from bovine aortic endothelial cells by Escherichia coli lipopolysaccharide Proceedings of the National Academy of Sciences of the United States of America. 87: 2593-2597. PMID 2181441 DOI: 10.1073/Pnas.87.7.2593  0.648
1990 Vane J. Endothelins come home to roost. Nature. 348: 673-673. PMID 2175394 DOI: 10.1038/348673A0  0.338
1990 Lidbury PS, Korbut R, Vane JR. Sodium nitroprusside modulates the fibrinolytic system in the rabbit. British Journal of Pharmacology. 101: 527-530. PMID 2127549 DOI: 10.1111/J.1476-5381.1990.Tb14115.X  0.395
1990 Lidbury PS, Thiemermann C, Korbut R, Vane JR. Endothelins release tissue plasminogen activator and prostanoids. European Journal of Pharmacology. 186: 205-212. PMID 2127021 DOI: 10.1016/0014-2999(90)90435-9  0.464
1990 Vane JR, Änggård EE, Botting RM. Regulatory functions of the vascular endothelium. The New England Journal of Medicine. 323: 27-36. PMID 2113184 DOI: 10.1056/Nejm199007053230106  0.41
1990 D'Orléans-Juste P, Lidbury PS, Warner TD, Vane JR. Intravascular big endothelin increases circulating levels of endothelin-1 and prostanoids in the rabbit Biochemical Pharmacology. 39. PMID 2110457 DOI: 10.1016/0006-2952(90)90419-L  0.369
1990 Spurej E, Sneddon JM, Vane JR. The influence of pH on aggregation of human washed platelets induced by thrombin or collagen. Blood Coagulation & Fibrinolysis. 1: 47-53. PMID 2102788 DOI: 10.1097/00001721-199003000-00008  0.437
1990 Walder CE, Thiemermann C, Vane JR. Endothelium-derived relaxing factor participates in the increased blood flow in response to pentagastrin in the rat stomach mucosa. Proceedings. Biological Sciences / the Royal Society. 241: 195-200. PMID 1979444 DOI: 10.1098/Rspb.1990.0085  0.459
1990 Sessa WC, Hecker M, Mitchell JA, Vane JR. The metabolism of L-arginine and its significance for the biosynthesis of endothelium-derived relaxing factor: L-glutamine inhibits the generation of L-arginine by cultured endothelial cells. Proceedings of the National Academy of Sciences of the United States of America. 87: 8607-11. PMID 1978327 DOI: 10.1073/Pnas.87.21.8607  0.395
1990 Salvemini D, Masini E, Anggard E, Mannaioni PF, Vane J. Synthesis of a nitric oxide-like factor from L-arginine by rat serosal mast cells: Stimulation of guanylate cyclase and inhibition of platelet aggregation Biochemical and Biophysical Research Communications. 169: 596-601. PMID 1972620 DOI: 10.1016/0006-291X(90)90372-T  0.601
1990 Korbut R, Lidbury PS, Vane JR. Prolongation of fibrinolytic activity of tissue plasminogen activator by nitrovasodilators. The Lancet. 335: 669. PMID 1969050 DOI: 10.1016/0140-6736(90)90462-E  0.335
1990 Sinzinger H, Fitscha P, O'Grady J, Rauscha F, Rogatti W, Vane J. Synergistic effect of prostaglandin E1 and isosorbide dinitrate in peripheral vascular disease. The Lancet. 335: 627-628. PMID 1969017 DOI: 10.1016/0140-6736(90)90412-X  0.436
1990 Salvemini D, Radziszewski W, Korbut R, Vane J. The use of oxyhaemoglobin to explore the events underlying inhibition of platelet aggregation induced by NO or NO-donors British Journal of Pharmacology. 101: 991-995. PMID 1707709 DOI: 10.1111/J.1476-5381.1990.Tb14194.X  0.58
1990 Thomas GR, Walder CE, Thiemermann C, Vane JR. Regional vascular resistance and haemodynamics in the spontaneously hypertensive rat: the effects of bradykinin. Journal of Cardiovascular Pharmacology. 15: 211-7. PMID 1689415 DOI: 10.1097/00005344-199002000-00006  0.3
1990 Mollace V, Salvemini D, Änggard E, Nisticò G, Vane J. Cultured astrocytoma cells release a nitric oxide-like factor Pharmacological Research. 22: 338. DOI: 10.1016/S1043-6618(09)80358-7  0.57
1990 Hecker M, Mitchell JA, Harris HJ, Katsura M, Thiemermann C, Vane JR. NG-monomethyl-L-arginine but not Nω-nitro-L-arginine is metabolized by endottielial cells to L-citrulline European Journal of Pharmacology. 183: 648-649. DOI: 10.1016/0014-2999(90)93576-C  0.369
1990 Sneddon J, Bearpark T, Vane J. L-Arginine transport in endothelial cells European Journal of Pharmacology. 183: 644. DOI: 10.1016/0014-2999(90)93571-7  0.272
1990 Mannaioni PF, Masini E, Salvemini D, Pistelli A, Korbut R, Vane JR. Mast cell derived relaxing factor and the effect of nitric oxide generators on mast cell histamine release European Journal of Pharmacology. 183: 711. DOI: 10.1016/0014-2999(90)92505-D  0.583
1989 Thiemermann C, Thomas GR, Vane JR. Defibrotide reduces infarct size in a rabbit model of experimental myocardial ischaemia and reperfusion. British Journal of Pharmacology. 97: 401-408. PMID 2758223 DOI: 10.1111/J.1476-5381.1989.Tb11967.X  0.378
1989 Lidbury PS, Thiemermann C, Thomas GR, Vane JR. Endothelin-3: selectivity as an anti-aggregatory peptide in vivo European Journal of Pharmacology. 166: 335-338. PMID 2676565 DOI: 10.1016/0014-2999(89)90079-4  0.483
1989 Korbut R, Lidbury P, Thomas GR, Vane JR. Fibrinolytic activity of endothelin-3 Thrombosis Research. 55: 797-799. PMID 2675389 DOI: 10.1016/0049-3848(89)90311-3  0.385
1989 Botting R, Vane JR. Mediators and the anti-thrombotic properties of the vascular endothelium. Annals of Medicine. 21: 31-8. PMID 2647108 DOI: 10.3109/07853898909149179  0.396
1989 Warner TD, de Nucci G, Vane JR. Rat endothelin is a vasodilator in the isolated perfused mesentery of the rat European Journal of Pharmacology. 159: 325-326. PMID 2646137 DOI: 10.1016/0014-2999(89)90167-2  0.399
1989 Salvemini D, De Nucci G, Sneddon JM, Vane JR. Superoxide anions enhance platelet adhesion and aggregation British Journal of Pharmacology. 97: 1145-1150. PMID 2551440 DOI: 10.1111/J.1476-5381.1989.Tb12572.X  0.547
1989 Salvemini D, De Nucci G, Gryglewski RJ, Vane JR. Human neutrophils and mononuclear cells inhibit platelet aggregation by releasing a nitric oxide-like factor Proceedings of the National Academy of Sciences of the United States of America. 86: 6328-6332. PMID 2548208 DOI: 10.1073/Pnas.86.16.6328  0.636
1989 D'Orléans-Juste P, de Nucci G, Vane JR. Kinins act on B1 or B2 receptors to release conjointly endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells. British Journal of Pharmacology. 96: 920-6. PMID 2545298 DOI: 10.1111/j.1476-5381.1989.tb11903.x  0.313
1989 Salvemini D, Korbut R, Änggård E, Vane JR. Lipopolysaccharide increases release of a nitric oxide-like factor from endothelial cells European Journal of Pharmacology. 171: 135-136. PMID 2515068 DOI: 10.1016/0014-2999(89)90437-8  0.579
1989 Barrett ML, Willis AL, Vane JR. Inhibition of platelet-derived mitogen release by nitric oxide (EDRF). Agents and Actions. 27: 488-91. PMID 2508448 DOI: 10.1007/Bf01972860  0.464
1989 Warner TD, De Nucci G, Vane JR. Comparison of the survival of endothelium-derived relaxing factor and nitric oxide within the isolated perfused mesenteric arterial bed of the rat British Journal of Pharmacology. 97: 777-782. PMID 2503227 DOI: 10.1111/J.1476-5381.1989.Tb12016.X  0.429
1989 D'Orleans-Juste P, De Nucci G, Vane JR. Endothelin-1 contracts isolated vessels independently of dihydropyridine-sensitive Ca2+ channel activation. European Journal of Pharmacology. 165: 289-95. PMID 2476324 DOI: 10.1016/0014-2999(89)90723-1  0.322
1989 Walder CE, Thomas GR, Thiemermann C, Vane JR. The hemodynamic effects of endothelin-1 in the pithed rat. Journal of Cardiovascular Pharmacology. 13: S93-7; discussion S1. PMID 2473337 DOI: 10.1097/00005344-198900135-00023  0.421
1989 Rae GA, Trybulec M, Nucci Gd, Vane JR. Endothelin-1 releases eicosanoids from rabbit isolated perfused kidney and spleen. Journal of Cardiovascular Pharmacology. 13. PMID 2473336 DOI: 10.1097/00005344-198900135-00022  0.43
1989 Warner TD, Mitchell JA, De Nucci G, Vane JR. Endothelin-1 and endothelin-3 release EDRF from isolated perfused arterial vessels of the rat and rabbit Journal of Cardiovascular Pharmacology. 13: S85-S88. PMID 2473335 DOI: 10.1097/00005344-198900135-00021  0.331
1989 Änggård E, Gallon S, Rae G, Thomas R, McLoughlin L, Nucci Gd, Vane JR. The fate of radioiodinated endothelin-1 and endothelin-3 in the rat. Journal of Cardiovascular Pharmacology. 13. PMID 2473326 DOI: 10.1097/00005344-198900135-00012  0.386
1989 Withrington PG, Nucci Gd, Vane JR. Endothelin-1 causes vasoconstriction and vasodilation in the blood perfused liver of the dog. Journal of Cardiovascular Pharmacology. 13. PMID 2473314 DOI: 10.1097/00005344-198900135-00060  0.4
1989 Thiemermann C, Lidbury PS, Thomas GR, Vane JR. Endothelin-1 releases prostacyclin and inhibits ex vivo platelet aggregation in the anesthetized rabbit. Journal of Cardiovascular Pharmacology. 13. DOI: 10.1097/00005344-198900135-00034  0.463
1989 DʼOrleans-Juste P, Finet M, de Nucci G, Vane JR. Pharmacology of Endothelin-1 in Isolated Vessels Journal of Cardiovascular Pharmacology. 13: S19-22. DOI: 10.1097/00005344-198900135-00007  0.274
1988 Thomas GR, Thiemermann C, Walder C, Vane JR. The effects of endothelium-dependent vasodilators on cardiac output and their distribution in the anaesthetized rat: a comparison with sodium nitroprusside. British Journal of Pharmacology. 95: 986-92. PMID 3264737 DOI: 10.1111/J.1476-5381.1988.Tb11729.X  0.423
1988 Sneddon JM, Vane JR. Endothelium-derived relaxing factor reduces platelet adhesion to bovine endothelial cells Proceedings of the National Academy of Sciences of the United States of America. 85: 2800-2804. PMID 3258664 DOI: 10.1073/Pnas.85.8.2800  0.467
1988 Thiemermann C, Lidbury P, Thomas R, Vane J. Endothelin inhibits ex vivo platelet aggregation in the rabbit. European Journal of Pharmacology. 158: 181-182. PMID 3065092 DOI: 10.1016/0014-2999(88)90273-7  0.433
1988 Gryglewski RJ, Botting RM, Vane JR. Mediators produced by the endothelial cell. Hypertension. 12: 530-548. PMID 3060428 DOI: 10.1161/01.Hyp.12.6.530  0.487
1988 de Nucci G, Thomas R, D'Orleans-Juste P, Antunes E, Walder C, Warner TD, Vane JR. Pressor effects of circulating endothelin are limited by its removal in the pulmonary circulation and by the release of prostacyclin and endothelium-derived relaxing factor. Proceedings of the National Academy of Sciences of the United States of America. 85: 9797-800. PMID 3059352 DOI: 10.1073/Pnas.85.24.9797  0.414
1988 De Nucci G, Warner T, Vane JR. Effect of captopril on the bradykinin-induced release of prostacyclin from guinea-pig lungs and bovine aortic endothelial cells British Journal of Pharmacology. 95: 783-788. PMID 2850062 DOI: 10.1111/J.1476-5381.1988.Tb11705.X  0.432
1988 De Nucci G, Gryglewski RJ, Warner TD, Vane JR. Receptor-mediated release of endothelium-derived relaxing factor and prostacyclin from bovine aortic endothelial cells is coupled Proceedings of the National Academy of Sciences of the United States of America. 85: 2334-2338. PMID 2832851 DOI: 10.1073/Pnas.85.7.2334  0.449
1987 Vane J. The evolution of non-steroidal anti-inflammatory drugs and their mechanisms of action. Drugs. 33: 18-27. PMID 3595474 DOI: 10.2165/00003495-198700331-00005  0.417
1987 Higgs GA, Salmon JA, Henderson B, Vane JR. Pharmacokinetics of aspirin and salicylate in relation to inhibition of arachidonate cyclooxygenase and antiinflammatory activity Proceedings of the National Academy of Sciences of the United States of America. 84: 1417-1420. PMID 3103135 DOI: 10.1073/Pnas.84.5.1417  0.442
1987 Vane J, Botting R. Inflammation and the mechanism of action of anti‐inflammatory drugs The Faseb Journal. 1: 89-96. DOI: 10.1096/fasebj.1.2.3111928  0.244
1987 Vane JR, Gryglewski RJ, Botting RM. The endothelial cell as a metabolic and endocrine organ Trends in Pharmacological Sciences. 8: 491-496. DOI: 10.1016/0165-6147(87)90045-9  0.441
1986 Higgs EA, Moncada S, Vane JR. Prostaglandins and thromboxanes from fatty acids. Progress in Lipid Research. 25: 5-11. PMID 2827190 DOI: 10.1016/0163-7827(86)90005-6  0.37
1985 Whittle BJ, Vane JR. A biochemical basis for the gastrointestinal toxicity of non-steroid antirheumatoid drugs. Archives of Toxicology. Supplement. = Archiv Fur Toxikologie. Supplement. 7: 315-22. PMID 6440513 DOI: 10.1007/978-3-642-69132-4_54  0.309
1984 Vane J, Cuatrecasas P. Genetic engineering and pharmaceuticals. Nature. 312: 303-5. PMID 6594576 DOI: 10.1038/312303A0  0.309
1984 Oliva D, Noè A, Nicosia S, Bernini F, Fumagalli R, Whittle BJR, Moncada S, Vane JR. Prostacyclin-sensitive adenylate cyclase in cultured myocytes: Differences between rabbit aorta and mesenteric artery European Journal of Pharmacology. 105: 207-213. PMID 6391937 DOI: 10.1016/0014-2999(84)90611-3  0.424
1984 Vane JR. Nobel lecture. Adventures and excursions in bioassay--the stepping stones to prostacyclin. Postgraduate Medical Journal. 59: 743-58. PMID 6361717 DOI: 10.1136/pgmj.59.698.743  0.203
1984 Vane JR. Nobel lecture, 8th December 1982. Adventures and excursions in bioassay: the stepping stones to prostacyclin. British Journal of Pharmacology. 79: 821-38. PMID 6360277 DOI: 10.1111/j.1476-5381.1983.tb10020.x  0.169
1984 Lombroso M, Nicosia S, Paoletti R, Whittle BJR, Moncada S, Vane JR. The use of stable prostaglandins to investigate prostacyclin (PGI2)-binding sites and PGI2-sensitive adenylate cyclase in human platelet membranes Prostaglandins. 27: 321-333. PMID 6326201 DOI: 10.1016/0090-6980(84)90083-2  0.377
1984 Higgs GA, Mugridge KG, Moncada S, Vane JR. Inhibition of tissue damage by the arachidonate lipoxygenase inhibitor BW755C Proceedings of the National Academy of Sciences of the United States of America. 81: 2890-2892. PMID 6326150 DOI: 10.1073/Pnas.81.9.2890  0.428
1984 Salmon JA, Higgs GA, Tilling L, Moncada S, Vane JR. Mode Of Action Of Benoxaprofen The Lancet. 323: 848. PMID 6143158 DOI: 10.1016/S0140-6736(84)92293-1  0.31
1984 VANE JR. ChemInform Abstract: BIOASSAY ADVENTURE ON THE WAY TO PROSTACYCLIN Chemischer Informationsdienst. 15. DOI: 10.1002/CHIN.198406348  0.214
1983 Higgs GA, Vane JR. Inhibition of cyclo-oxygenase and lipoxygenase. British Medical Bulletin. 39: 265-70. PMID 6414573 DOI: 10.1093/OXFORDJOURNALS.BMB.A071831  0.316
1983 Salmon JA, Higgs GA, Vane JR, Bitensky L, Chayen J, Henderson B, Cashman B. Synthesis of arachidonate cyclo-oxygenase products by rheumatoid and nonrheumatoid synovial lining in nonproliferative organ culture. Annals of the Rheumatic Diseases. 42: 36-9. PMID 6402992 DOI: 10.1136/ard.42.1.36  0.243
1983 Bunting S, Moncada S, Vane JR. The prostacyclin-thromboxane A2 balance: Pathophysiological and therapeutic implications British Medical Bulletin. 39: 271-276. PMID 6354352 DOI: 10.1093/Oxfordjournals.Bmb.A071832  0.316
1983 Vane JR. Adventures and excursions in bioassay: the stepping stones to prostacyclin. Nobel Lecture, 8 December 1982. Bioscience Reports. 3: 683-711. PMID 6354296 DOI: 10.1007/bf01120983  0.201
1983 Whittle BJR, Monacada S, Mullane K, Vane JR. Platelet and cardiovascular activity of the hydantoin BW245C, a potent prostaglandin analogue Prostaglandins. 25: 205-223. PMID 6344147 DOI: 10.1016/0090-6980(83)90105-3  0.456
1983 Vane JR. Prostaglandins and the cardiovascular system. British Heart Journal. 49: 405-9. PMID 6340706 DOI: 10.1136/hrt.49.5.405  0.235
1983 Vane JR. Prostacyclin Journal of the Royal Society of Medicine. 76: 245-249. DOI: 10.1177/014107688307600401  0.34
1983 Vane JR. Adventures and Excursions in Bioassay: The Stepping Stones to Prostacyclin (Noble Lecture) Angewandte Chemie International Edition in English. 22: 741-752. DOI: 10.1002/ANIE.198307413  0.202
1981 Moncada S, Vane JR. Prostacyclin and blood coagulation. Drugs. 21: 430-7. PMID 7018874 DOI: 10.2165/00003495-198121060-00002  0.347
1981 Vane JR, Moncada S. The anti-thrombotic effects of prostacyclin. Acta Medica Scandinavica. Supplementum. 642: 11-22. PMID 7006326 DOI: 10.1111/J.0954-6820.1980.TB10930.X  0.262
1981 Mundy AR, Bewick M, Moncada S, Vane JR. Experimental assessment of prostacyclin in the harvesting of kidneys for transplantation. Transplantation. 30: 251-5. PMID 7003843 DOI: 10.1097/00007890-198010000-00003  0.288
1981 Moncada S, Vane JR. Prostacyclin: homeostatic regulator or biological curiosity? Clinical Science (London, England : 1979). 61: 369-72. PMID 6269790 DOI: 10.1042/CS0610369  0.189
1981 Moncada S, Vane JR. Interrelationships between prostacyclin and thromboxane A2. Ciba Foundation Symposium. 78: 165-83. PMID 6258879 DOI: 10.1002/9780470720615.CH9  0.376
1981 Moncada S, Vane JR. Prostacyclin: its biosynthesis, actions and clinical potential. Philosophical Transactions of the Royal Society B. 294: 305-329. PMID 6117893 DOI: 10.1098/Rstb.1981.0108  0.462
1980 Higgs GA, Eakins KE, Mugridge KG, Moncada S, Vane Jr. The effects of non-steroid anti-inflammatory drugs on leukocyte migration in carrageenin-induced inflammation European Journal of Pharmacology. 66: 81-86. PMID 7408965 DOI: 10.1016/0014-2999(80)90297-6  0.434
1980 Woods HF, Weston MJ, Bunting S, Moncada S, Vane J. Prostacyclin eliminates the thrombocytopenia associated with charcoal hemoperfusion and minimizes heparin and fibrinogen consumption Artificial Organs. 4: 176-179. PMID 6998437 DOI: 10.1111/J.1525-1594.1980.Tb03930.X  0.374
1980 Moncada S, Vane JR. Biological significance and therapeutic potential of prostacyclin. Journal of Medicinal Chemistry. 23: 591-3. PMID 6993680 DOI: 10.1021/JM00180A001  0.206
1980 Whittle BJR, Moncada S, Whiting F, Vane JR. Carbacyclin - A potent stable prost acyclin analogue for the inhibition of platelet aggregation Prostaglandins. 19: 605-627. PMID 6992234 DOI: 10.1016/S0090-6980(80)80010-4  0.467
1980 Mundy AR, Bewick M, Moncada S, Vane JR. Short term suppression of hyperacute renal allograft rejection in presensitised dogs with prostacyclin. Prostaglandins. 19: 595-603. PMID 6992233 DOI: 10.1016/S0090-6980(80)80009-8  0.292
1980 Whittle BJR, Higgs GA, Eakins KE, Moncada S, Vane JR. Selective inhibition of prostaglandin production in inflammatory exudates and gastric mucosa Nature. 284: 271-273. PMID 6767192 DOI: 10.1038/284271A0  0.404
1980 Chapple DJ, Dusting GJ, Hughes R, Vane JR. Some direct and reflex cardiovascular actions of prostacyclin (PGI2) and prostaglandin E2 in anaesthetized dogs. British Journal of Pharmacology. 68: 437-447. PMID 6762901 DOI: 10.1111/J.1476-5381.1980.Tb14557.X  0.41
1980 Higgs GA, Eakins KE, Moncada S, Vane JR. Arachidonic acid metabolism in inflammation and the mode of action of anti-inflammatory drugs. Agents and Actions. Supplements. 167-75. PMID 118657 DOI: 10.1007/978-3-0348-7232-4_19  0.261
1980 MONCADA S, VANE JR. ChemInform Abstract: BIOLOGICAL SIGNIFICANCE AND THERAPEUTIC POTENTIAL OF PROSTACYCLIN Chemischer Informationsdienst. 11. DOI: 10.1002/CHIN.198042287  0.215
1979 Gryglewski RJ, Salmon JA, Ubatuba FB, Weatherly BC, Moncada S, Vane JR. Effects of all CIS-5, 8,11,14,17 eicosapentaenoic acid and PGH3 on platelet aggregation Prostaglandins. 18: 453-478. PMID 531220 DOI: 10.1016/S0090-6980(79)80063-5  0.451
1979 Mullane KM, Dusting GJ, Salmon JA, Moncada S, Vane JR. Biotransformation and cardiovascular effects of arachidonic acid in the dog. European Journal of Pharmacology. 54: 217-228. PMID 428423 DOI: 10.1016/0014-2999(79)90080-3  0.453
1979 Higgs GA, Cardinal DC, Moncada S, Vane JR. Microcirculatory effects of prostacyclin (PGI2) in the hamster cheek pouch. Microvascular Research. 18: 245-254. PMID 386050 DOI: 10.1016/0026-2862(79)90032-3  0.444
1979 Dusting GJ, Moncada S, Vane JR. Prostaglandins, their intermediates and precursors: Cardiovascular actions and regulatory roles in normal and abnormal circulatory systems Progress in Cardiovascular Diseases. 21: 405-430. PMID 375296 DOI: 10.1016/0033-0620(79)90024-0  0.431
1979 Moncada S, Vane JR. Arachidonic acid metabolites and the interactions between platelets and blood-vessel walls. The New England Journal of Medicine. 300: 1142-7. PMID 219340 DOI: 10.1056/NEJM197905173002006  0.317
1979 Herman AG, Claeys M, Moncada S, Vane JR. Biosynthesis of prostacyclin (PGI2) and 12L-hydroxy-5,8,10,14-eicosatetraenoic acid (HETE) by pericardium, pleura, peritoneum and aorta of the rabbit Prostaglandins. 18: 439-452. PMID 119280 DOI: 10.1016/S0090-6980(79)80062-3  0.436
1979 Vane JR. Finding the resources to fight tropical diseases. Transactions of the Royal Society of Tropical Medicine and Hygiene. 73: 140-3. PMID 112728 DOI: 10.1016/0035-9203(79)90195-0  0.17
1979 Higgs GA, Flower RJ, Vane JR. A new approach to anti-inflammatory drugs. Biochemical Pharmacology. 28: 1959-1961. PMID 110332 DOI: 10.1016/0006-2952(79)90651-8  0.447
1979 Longmore DB, Gueirrara D, Bennett G, Smith M, Bunting S, Moncada S, Reed P, Read NG, Vane JR. PROSTACYCLIN: A SOLUTION TO SOME PROBLEMS OF EXTRACORPOREAL CIRCULATION: Experiments in Greyhounds The Lancet. 313: 1002-1005. PMID 86720 DOI: 10.1016/S0140-6736(79)92756-9  0.404
1979 Salmon JA, Mullane KM, Dusting GJ, Moncada S, Vane JR. Elimination of prostacyclin (PGI2) and 6-oxo-PGF1 alpha in anaesthetized dogs. Journal of Pharmacy and Pharmacology. 31: 529-532. PMID 39993 DOI: 10.1111/J.2042-7158.1979.Tb13577.X  0.325
1979 Ubatuba FB, Moncada S, Vane JR. The effect of prostacyclin (PGT2) on platelet behaviour. Thrombus formation in vivo and bleeding time. Thrombosis and Haemostasis. 41: 425-435. DOI: 10.1055/S-0038-1646791  0.473
1979 Kauffman G, Whittle B, Aures D, Vane J, Grossman M. Effects of prostacyclin and a stable analogue, 6β-PGI1, on gastric acid secretion, mucosal blood flow, and blood pressure in conscious dogs Gastroenterology. 77: 1301-1306. DOI: 10.1016/0016-5085(79)90171-9  0.277
1978 Blackwell GJ, Flower RJ, Nijkamp FP, Vane JR. Phospholipase A2 activity of guinea-pig isolated perfused lungs: stimulation, and inhibition by anti-inflammatory steroids. British Journal of Pharmacology. 62: 79-89. PMID 620100 DOI: 10.1111/J.1476-5381.1978.Tb07009.X  0.421
1978 Salmon JA, Smith DR, Flower RJ, Moncada S, Vane JR. Further studies on the enzymatic conversion of prostaglandin endoperoxide into prostacyclin by porcine aorta microsomes. Biochimica Et Biophysica Acta. 523: 250-262. PMID 415760 DOI: 10.1016/0005-2744(78)90028-1  0.396
1978 Dusting GJ, Moncada S, Mullane KM, Vane JR. Implications of prostacyclin generation for modulation of vascular tone. Clinical Science. 4. PMID 365431 DOI: 10.1042/Cs055195S  0.429
1978 Whittle BJR, Moncada S, Vane JR. Comparison of the effects of prostacyclin (PGI2), prostaglandin E1 and D2 on platelet aggregation in different species. Prostaglandins. 16: 373-388. PMID 364545 DOI: 10.1016/0090-6980(78)90216-2  0.456
1978 Dusting GJ, Moncada S, Vane JR. Recirculation of prostacyclin (PGI2) in the dog. British Journal of Pharmacology. 64: 315-320. PMID 361136 DOI: 10.1111/J.1476-5381.1978.Tb17307.X  0.407
1978 Higgs EA, Moncada S, Vane JR. Inflammatory effects of prostacyclin (PGI2) and 6-oxo-PGF1α in the rat paw Prostaglandins. 16: 153-162. PMID 360302 DOI: 10.1016/0090-6980(78)90018-7  0.423
1978 Higgs EA, Moncada S, Vane JR, Caen JP, Michel H, Tobelem G. Effect of prostacyclin (PGI2) on platelet adhesion to rabbit arterial subendothelium. Prostaglandins. 16: 17-22. PMID 360299 DOI: 10.1016/0090-6980(78)90197-1  0.454
1978 Whittle BJR, Boughton-Smith NK, Moncada S, Vane JR. Actions of prostacyclin (PGI2) and its product, 6-oxo-PGF1α on the rat gastric mucosa in vivo and in vitro Prostaglandins. 15: 955-967. PMID 358297 DOI: 10.1016/0090-6980(78)90038-2  0.415
1978 Bunting S, Moncada S, Reed P, Salmon JA, Vane JR. An antiserum to 5,6-dihydro prostacyclin (PGI1) which also binds prostacyclin. Prostaglandins. 15: 565-73. PMID 353902 DOI: 10.1016/0090-6980(78)90053-9  0.456
1978 Moncada S, Korbut R, Bunting S, Vane JR. Prostacyclin is a circulating hormone Nature. 273: 767-768. PMID 351418 DOI: 10.1038/273767A0  0.472
1978 Dusting GJ, Moncada S, Vane JR. Vascular actions of arachidonic acid and its metabolites in perfused mesenteric and femoral beds of the dog. European Journal of Pharmacology. 49: 65-72. PMID 350595 DOI: 10.1016/0014-2999(78)90222-4  0.459
1978 Moncada S, Vane JR. Unstable metabolites of arachidonic acid and their role in haemostasis and thrombosis. British Medical Bulletin. 34: 129-35. PMID 350335 DOI: 10.1093/OXFORDJOURNALS.BMB.A071482  0.24
1978 Moncada S, Vane JR. Interaction between anti-inflammatory drugs and inflammatory mediators. A reference to products of arachidonic acid metabolism. Agents and Actions. Supplements. 141-8. PMID 343556 DOI: 10.1007/978-3-0348-7290-4_14  0.266
1978 Armstrong JM, Lattimer N, Moncada S, Vane JR. COMPARISON OF THE VASODEPRESSOR EFFECTS OF PROSTACYCLIN AND 6-OXO-PROSTAGLANDIN F1α WITH THOSE OF PROSTAGLANDIN E2 IN RATS AND RABBITS British Journal of Pharmacology. 62: 125-130. PMID 339981 DOI: 10.1111/J.1476-5381.1978.Tb07014.X  0.427
1978 Omini C, Moncada S, Vane JR. The effects of prostacyclin (PGI2) on tissues which detect prostaglandins (PG'S). Prostaglandins. 14: 625-32. PMID 339280 DOI: 10.1016/0090-6980(77)90189-7  0.313
1978 Schrör K, Moncada S, Ubatuba FB, Vane JR. Transformation of arachidonic acid and prostaglandin endoperoxides by the guinea pig heart. Formation of RCS and prostacyclin. European Journal of Pharmacology. 47: 103-114. PMID 338313 DOI: 10.1016/0014-2999(78)90380-1  0.42
1978 Vane JR. The mode of action of aspirin-like drugs. Agents and Actions. 8: 430-1. PMID 98977 DOI: 10.1007/BF01968671  0.227
1978 Woods HF, Ash G, Weston MJ, Bunting S, Moncada S, Vane JR. PROSTACYCLIN CAN REPLACE HEPARIN IN HÆMODIALYSIS IN DOGS The Lancet. 312: 1075-1077. PMID 82090 DOI: 10.1016/S0140-6736(78)91806-8  0.432
1978 Dyerberg J, Bang HO, Stoffersen E, Moncada S, Vane JR. Eicosapentaenoic acid and prevention of thrombosis and atherosclerosis The Lancet. 312: 117-119. PMID 78322 DOI: 10.1016/S0140-6736(78)91505-2  0.386
1978 Whittle BJR, Boughton-Smith NK, Moncada S, Vane JR. The relative activity of prostacyclin (PGI2) and a stable analogue 6β-PGI1 on the gastrointestinal and cardiovascular systems Journal of Pharmacy and Pharmacology. 30: 597-599. PMID 29109 DOI: 10.1111/J.2042-7158.1978.Tb13338.X  0.331
1978 Dusting GJ, Chapple DJ, Hughes R, Moncada S, Vane JR. Prostacyclin (PGI2) induces coronary vasodilatation in anaesthetised dogs Cardiovascular Research. 12: 620-630. DOI: 10.1093/Cvr/12.10.620  0.382
1978 Woods HF, Weston MJ, Bunting S, Moncada S, Vane JR. Prostacyclin is a Heparin-Sparing Agent during Haemodialysis Clinical Science. 55. DOI: 10.1042/Cs055029Pa  0.329
1977 Cottee F, Flower RJ, Moncada S, Salmon JA, Vane JR. Synthesis of 6-keto-PGF1α by ram seminal vesicle microsomes Prostaglandins. 14: 413-423. PMID 905569 DOI: 10.1016/0090-6980(77)90257-X  0.413
1977 Dusting GJ, Moncada S, Vane JR. Prostacyclin (PGX) is the endogenous metabolite responsible for relaxation of coronary arteries induced by arachindonic acid. Prostaglandins. 13: 3-15. PMID 841106 DOI: 10.1016/0090-6980(77)90037-5  0.314
1977 Blackwell GJ, Duncombe WG, Flower RJ, Parsons MF, Vane JR. The distribution and metabolism of arachidonic acid in rabbit platelets during aggregation and its modification by drugs. British Journal of Pharmacology. 59: 353-366. PMID 837023 DOI: 10.1111/J.1476-5381.1977.Tb07500.X  0.445
1977 Vane JR. The mode of action of aspirin and similar compounds. The Journal of Allergy and Clinical Immunology. 58: 691-712. PMID 791988 DOI: 10.1016/0091-6749(76)90181-0  0.279
1977 Moncada S, Bunting S, Mullane K, Thorogood P, Vane JR, Raz A, Needleman P. Imidazole: a selective inhibitor of thromboxane synthetase. Prostaglandins. 13: 611-8. PMID 558637 DOI: 10.1016/0090-6980(77)90232-5  0.422
1977 Nijkamp FP, Moncada S, White HL, Vane JR. Diversion of prostaglandin endoperoxide metabolism by selective inhibition of thromboxane A2 biosynthesis in lung, spleen or platelets European Journal of Pharmacology. 44: 179-186. PMID 407090 DOI: 10.1016/0014-2999(77)90104-2  0.436
1977 Dusting GJ, Moncada S, Vane JR. Prostacyclin (PGI2) is a weak contractor of coronary arteries of the pig. European Journal of Pharmacology. 45: 301-304. PMID 336382 DOI: 10.1016/0014-2999(77)90014-0  0.391
1977 Moncada S, Herman AG, Higgs EA, Vane JR. Differential formation of prostacyclin (PGX or PGI2) by layers of the arterial wall. An explanation for the anti-thrombotic properties of vascular endothelium. Thrombosis Research. 11: 323-344. PMID 335560 DOI: 10.1016/0049-3848(77)90185-2  0.421
1977 Tateson JE, Moncada S, Vane JR. Effects of prostacyclin (PGX) on cyclic AMP concentrations in human platelets. Prostaglandins. 13: 389-97. PMID 191877 DOI: 10.1016/0090-6980(77)90019-3  0.332
1977 Bunting S, Moncada S, Vane JR. ANTITHROMBOTIC PROPERTIES OF VASCULAR ENDOTHELIUM The Lancet. 310: 1075-1076. PMID 72976 DOI: 10.1016/S0140-6736(77)91906-7  0.359
1977 Moncada S, Higgs EA, Vane JR. Human Arterial And Venous Tissues Generate Prostacyclin (Prostaglandin X), A Potent Inhibitor Of Platelet Aggregation The Lancet. 309: 18-21. PMID 63657 DOI: 10.1016/S0140-6736(77)91655-5  0.447
1977 Beddell CR, Clark RB, Hardy GW, Lowe LA, Ubatuba FB, Vane JR, Wilkinson S. Structural requirements for opioid activity of analogues of the enkephalins. Proceedings of the Royal Society of London. Series B, Biological Sciences. 198: 249-65. PMID 19753 DOI: 10.1098/rspb.1977.0096  0.197
1977 SCHROR K, MONCADA S, UBATUBA F, VANE J. Biosynthesis and function of prostacyclin (PGX) in the heart Journal of Molecular and Cellular Cardiology. 9: 47-48. DOI: 10.1016/S0022-2828(77)80324-6  0.202
1977 Moncada S, Grylewski R, Bunting S, Vane JR. An Enzyme Isolated from Arteries Transforms Prostaglandin Endoperoxides to an Unstable Substance that Inhibits Platelet Aggregation. Cheminform. 8. DOI: 10.1002/Chin.197706329  0.424
1976 Armstrong JM, Blackwell GJ, Flower RJ, McGiff JC, Mullane KM, Vane JR. Genetic hypertension in rats is accompanied by a defect in renal prostaglandin catabolism. Nature. 260: 582-586. PMID 1264220 DOI: 10.1038/260582A0  0.391
1976 Ferreira SH, Herman AG, Vane JR. Prostaglandin production by rabbit isolated jejunum and its relationship to the inherent tone of the preparation. British Journal of Pharmacology. 56: 469-77. PMID 1260227 DOI: 10.1111/j.1476-5381.1976.tb07459.x  0.328
1976 Blackwell GJ, Flower RJ, Vane JR. Rapid reduction of prostaglandin 15-hydroxy dehydrogenase activity in rat tissues after treatment with protein synthesis inhibitors. British Journal of Pharmacology. 55: 233-8. PMID 1201382 DOI: 10.1111/j.1476-5381.1975.tb07633.x  0.289
1976 Bunting S, Moncada S, Vane JR, Gryglewski R. Arterial walls generate from prostaglandin endoperoxides a substance (prostaglandin X) which relaxes strips of mesenteric and coeliac arteries and inhibits platelet aggregation Prostaglandins. 12: 897-913. PMID 1005741 DOI: 10.1016/0090-6980(76)90125-8  0.477
1976 Higgs GA, Bunting S, Moncada S, Vane JR. Polymorphonuclear leukocytes produce thromboxane A2-like activity during phagocytosis Prostaglandins. 12: 749-757. PMID 981700 DOI: 10.1016/0090-6980(76)90050-2  0.412
1976 Nijkamp FP, Flower RJ, Moncada S, Vane JR. Partial purification of rabbit aorta contracting substance-releasing factor and inhibition of its activity by anti-inflammatory steroids Nature. 263: 479-482. PMID 972692 DOI: 10.1038/263479A0  0.431
1976 Moncada S, Needleman P, Bunting S, Vane JR. Prostaglandin endoperoxide and thromboxane generating systems and their selective inhibition. Prostaglandins. 12: 323-35. PMID 968048 DOI: 10.1016/0090-6980(76)90014-9  0.413
1976 Staszewka-Barczak J, Ferreira SH, Vane JR. An excitatory nociceptive cardiac reflex elicited by bradykinin and potentiated by prostaglandins and myocardial ischaemia. Cardiovascular Research. 10: 314-27. PMID 954016 DOI: 10.1093/CVR/10.3.314  0.291
1976 Ferreira SH, Ubatuba FB, Vane JR. Platelets, acute inflammation and inflammatory mediators. Agents and Actions. 6: 313-7. PMID 941805 DOI: 10.1007/BF01972248  0.365
1976 Needleman P, Moncada S, Bunting S, Vane JR, Hamberg M, Samuelsson B. Identification of an enzyme in platelet microsomes which generates thromboxane A2 from prostaglandin endoperoxides. Nature. 261: 558-60. PMID 934294 DOI: 10.1038/261558A0  0.411
1976 Moncada S, Gryglewski RJ, Bunting S, Vane JR. A lipid peroxide inhibits the enzyme in blood vessel microsomes that generates from prostaglandin endoperoxides the substance (prostaglandin X) which prevents platelet aggregation Prostaglandins. 12: 715-737. PMID 824686 DOI: 10.1016/0090-6980(76)90048-4  0.461
1976 Gryglewski RJ, Bunting S, Moncada S, Flower RJ, Vane JR. Arterial walls are protected against deposition of platelet thrombi by a substance (prostaglandin X) which they make from prostaglandin endoperoxides Prostaglandins. 12: 685-713. PMID 824685 DOI: 10.1016/0090-6980(76)90047-2  0.481
1976 Moncada S, Gryglewski R, Bunting S, Vane JR. An enzyme isolated from arteries transforms prostaglandin endoperoxides to an unstable substance that inhibits platelet aggregation Nature. 263: 663-665. PMID 802670 DOI: 10.1038/263663A0  0.465
1976 Herman AG, Vane JR. Release of renal prostaglandins during endotoxin-induced hypotension. European Journal of Pharmacology. 39: 79-90. PMID 786701 DOI: 10.1016/0014-2999(76)90115-1  0.355
1976 Williams KI, Vane JR. Inhibition of uterine motility: the possible role of the prostaglandins and aspirin-like drugs. Pharmacology & Therapeutics. Part B: General & Systematic Pharmacology. 1: 89-113. PMID 772702 DOI: 10.1016/0306-039X(75)90018-5  0.291
1976 Johnson RA, Morton DR, Kinner JH, Gorman RR, McGuire JC, Sun FF, Whittaker N, Bunting S, Salmon J, Moncada S, Vane JR. The chemical structure of prostaglandin X (prostacyclin) Prostaglandins. 12: 915-928. PMID 12538 DOI: 10.1016/0090-6980(76)90126-X  0.335
1976 Higgs GA, Vane JR, Hart RJ, Potter C, Wilson RG. Prostaglandins in the saliva of the cattle tick, Boophilus microplus (Canestrini) (Acarina, Ixodidae) Bulletin of Entomological Research. 66: 665-670. DOI: 10.1017/S0007485300010725  0.265
1976 Vane JR. Introduction pharmacokinetic functions of lung Agents and Actions. 6: 493-493. DOI: 10.1007/BF01973266  0.193
1975 Ferreira SH, Flower RJ, Parsons MF, Vane JR. Letter: Reduction of the inflammatory response in rats immunized against prostaglandins. Prostaglandins. 8: 433-7. PMID 4453628 DOI: 10.1016/0090-6980(74)90122-1  0.25
1975 Vane JR, Williams KI. A sensitive method for the assay of oxytocin in the circulating blood. British Journal of Pharmacology. 52: 295-305. PMID 4451824 DOI: 10.1111/j.1476-5381.1974.tb09713.x  0.321
1975 Bakhle YS, Vane JR. Pharmacokinetic function of the pulmonary circulation. Physiological Reviews. 54: 1007-45. PMID 4371230 DOI: 10.1152/PHYSREV.1974.54.4.1007  0.205
1975 Moncada S, Ferreira SH, Vane JR. Inhibition of prostaglandin biosynthesis as the mechanism of analgesia of aspirin-like drugs in the dog knee joint. European Journal of Pharmacology. 31: 250-60. PMID 1149792 DOI: 10.1016/0014-2999(75)90047-3  0.296
1975 Block AJ, Feinberg H, Herbaczynska-Cedro K, Vane JR. Anoxia-induced release of prostaglandins in rabbit isolated hearts. Circulation Research. 36: 34-5. PMID 1116227 DOI: 10.1161/01.RES.36.1.34  0.325
1975 Vane JR, McGiff JC. Possible contributions of endogenous prostaglandins to the control of blood pressure. Circulation Research. 36: 68-75. PMID 805673 DOI: 10.1161/01.RES.36.6.68  0.324
1975 Blackwell GJ, Flower RJ, Vane JR. Some characteristics of the prostaglandin synthesizing system in rabbit kidney microsomes. Biochimica Et Biophysica Acta. 398: 178-90. PMID 238646 DOI: 10.1016/0005-2760(75)90181-2  0.301
1975 Vane J, Ferreira S. Interactions between bradykinin and prostaglandins Life Sciences. 16: 804-805. DOI: 10.1016/0024-3205(75)90388-4  0.207
1974 Herbaczynska-Cedro K, Vane JR. Prostaglandins as mediators of reactive hyperaemia in kidney. Nature. 247: 492. PMID 4818550 DOI: 10.1038/247492A0  0.252
1974 Vane JR, Williams KI. The contribution of prostaglandin production to contractions of the isolated uterus of the rat. British Journal of Pharmacology. 48: 629-39. PMID 4788206 DOI: 10.1111/j.1476-5381.1973.tb08250.x  0.304
1974 Ferreira SH, Moncada S, Vane JR. The blockade of the local generation of prostaglandins explains the analgesic action of aspirin. Agents and Actions. 3: 385. PMID 4785043 DOI: 10.1007/BF01986508  0.249
1974 Higgs GA, Vane JR. An improved method for the extraction of prostaglandins. Prostaglandins. 4: 695-9. PMID 4781515 DOI: 10.1016/S0090-6980(73)80052-8  0.189
1974 Ferreira SH, Ng KK, Vane JR. The continuous bioassay of the release and disappearance of histamine in the circulation. British Journal of Pharmacology. 49: 543-53. PMID 4777714 DOI: 10.1111/j.1476-5381.1973.tb17265.x  0.329
1974 Flower RJ, Vane JR. Inhibition of prostaglandin biosynthesis. Biochemical Pharmacology. 23: 1439-50. PMID 4603208 DOI: 10.1016/0006-2952(74)90381-5  0.316
1974 Moncada S, Ferreira SH, Vane JR. Prostaglandins, aspirin-like drugs and the oedema of inflammation. Nature. 246: 217-9. PMID 4586794 DOI: 10.1038/246217A0  0.257
1974 Leary WP, Ledingham JG, Vane JR. Impaired prostaglandin release from the kidneys of salt-loaded and hypertensive rats. Prostaglandins. 7: 425-32. PMID 4421506 DOI: 10.1016/0090-6980(74)90107-5  0.269
1974 Block AJ, Poole S, Vane JR. Modification of basal release of prostaglandins from rabbit isolated hearts. Prostaglandins. 7: 473-86. PMID 4414700 DOI: 10.1016/0090-6980(74)90092-6  0.269
1974 Cross SA, Alabaster VA, Bakhle YS, Vane JR. Sites of uptake of 3H-5-hydroxytryptamine in rat isolated lung. Histochemistry. 39: 83-91. PMID 4407266 DOI: 10.1007/BF02428554  0.231
1974 Ferreira SH, Moncada S, Vane JR. Prostaglandins and the mechanism of analgesia produced by aspirin-like drugs. British Journal of Pharmacology. 49: 86-97. PMID 4207046 DOI: 10.1111/j.1476-5381.1973.tb08270.x  0.335
1974 Ferreira SH, Vane JR. New Aspects of the Mode of Action of Nonsteroid Anti-Inflammatory Drugs Annual Review of Pharmacology. 14: 57-73. DOI: 10.1146/ANNUREV.PA.14.040174.000421  0.242
1973 Gryglewski R, Vane JR. The generation from arachidonic acid of rabbit aorta contracting substance (RCS) by a microsomal enzyme preparation which also generates prostaglandins. British Journal of Pharmacology. 46: 449-57. PMID 4656606 DOI: 10.1111/j.1476-5381.1972.tb08142.x  0.361
1973 Flower RJ, Vane JR. Inhibition of prostaglandin synthetase in brain explains the anti-pyretic activity of paracetamol (4-acetamidophenol). Nature. 240: 410-1. PMID 4564318 DOI: 10.1038/240410A0  0.273
1973 Herbaczynska-Cedro K, Vane JR. Contribution of intrarenal generation of prostaglandin to autoregulation of renal blood flow in the dog. Circulation Research. 33: 428-36. PMID 4355037 DOI: 10.1161/01.RES.33.4.428  0.256
1973 Ferreira SH, Moncada S, Vane JR. Some effects of inhibiting endogenous prostaglandin formation on the responses of the cat spleen. British Journal of Pharmacology. 47: 48-58. PMID 4352087 DOI: 10.1111/j.1476-5381.1973.tb08157.x  0.322
1973 Palmer MA, Piper PJ, Vane JR. Release of rabbit aorta contracting substance (RCS) and prostaglandins induced by chemical or mechanical stimulation of guinea-pig lungs. British Journal of Pharmacology. 49: 226-42. PMID 4135341 DOI: 10.1111/j.1476-5381.1973.tb08368.x  0.344
1973 Collier JG, Robinson BF, Vane JR. Reduction of pressor effects of angiotensin I in man by synthetic nonapeptide (B.P.P. 9a or SQ 20,881) which inhibits converting enzyme. Lancet (London, England). 1: 72-4. PMID 4118651 DOI: 10.1016/S0140-6736(73)90468-6  0.254
1973 VANE JR. Inflammatory Substances Nature. 242: 141-141. DOI: 10.1038/242141a0  0.237
1972 Pojda SM, Vane JR. Inhibitory effects of aprotinin on kallikrein and kininases in dog's blood. British Journal of Pharmacology. 42: 558-68. PMID 5315684 DOI: 10.1111/j.1476-5381.1971.tb07140.x  0.337
1972 Eckenfels A, Vane JR. Prostaglandins, oxygen tension and smooth muscle tone. British Journal of Pharmacology. 45: 451-62. PMID 5072227 DOI: 10.1111/j.1476-5381.1972.tb08101.x  0.287
1972 Gryglewski R, Vane JR. The release of prostaglandins and rabbit aorta contracting substance (RCS) from rabbit spleen and its antagonism by anti-inflammatory drugs. British Journal of Pharmacology. 45: 37-47. PMID 5041506 DOI: 10.1111/j.1476-5381.1972.tb09574.x  0.347
1972 Eble JN, Gowdey CW, Vane JR. Blood concentrations of adrenaline in dogs after intravenous administration of 5-hydroxytryptamine. Nature: New Biology. 238: 254-6. PMID 4507302 DOI: 10.1038/NEWBIO238254A0  0.289
1972 Flower R, Gryglewski R, Herbaczyńska-Cedro K, Vane JR. Effects of anti-inflammatory drugs on prostaglandin biosynthesis. Nature: New Biology. 238: 104-6. PMID 4505422 DOI: 10.1038/NEWBIO238104A0  0.263
1972 Aiken JW, Vane JR. Inhibition of converting enzyme of the renin-angiotensin system in kidneys and hindlegs of dogs. Circulation Research. 30: 263-73. PMID 4334163 DOI: 10.1161/01.RES.30.3.263  0.28
1972 Vane JR. Prostaglandins and the Aspirin-Like Drugs Hospital Practice. 7: 61-71. DOI: 10.1080/21548331.1972.11706162  0.237
1971 Gilmore NJ, Vane JR. Hormones released into the circulation when the urinary bladder of the anaesthetized dog is distended. Clinical Science. 41: 69-83. PMID 5559114 DOI: 10.1042/CS0410069  0.257
1971 Ferreira SH, Moncada S, Vane JR. Indomethacin and aspirin abolish prostaglandin release from the spleen. Nature: New Biology. 231: 237-9. PMID 5284362 DOI: 10.1038/NEWBIO231237A0  0.306
1971 Vane JR. Inhibition of prostaglandin synthesis as a mechanism of action for aspirin-like drugs. Nature: New Biology. 231: 232-5. PMID 5284360 DOI: 10.1038/NEWBIO231232A0  0.301
1971 Eble JN, Gowdey CW, Vane JR. Blood concentration of noradrenaline in the dog after intravenous administration and the effects of desipramine. Nature. 231: 181-2. PMID 4930674 DOI: 10.1038/231181A0  0.301
1971 Vane JR. Purity and stability of synthetic peptides such as angiotensins and kinins. Nature. 230: 382. PMID 4323825 DOI: 10.1038/230382A0  0.195
1971 Piper P, Vane J. The release of prostaglandins from lung and other tissues. Annals of the New York Academy of Sciences. 180: 363-85. PMID 4106477 DOI: 10.1111/j.1749-6632.1971.tb53205.x  0.241
1970 Gryglewski R, Vane JR. The inactivation of noradrenaline and isoprenaline in dogs. British Journal of Pharmacology. 39: 573-84. PMID 5472204 DOI: 10.1111/j.1476-5381.1970.tb10365.x  0.307
1970 Berry HE, Collier JG, Vane JR. The generation of kinins in the blood of dogs during hypotension due to haemorrhage. Clinical Science. 39: 349-65. PMID 5459163 DOI: 10.1042/CS0390349  0.272
1970 Piper PJ, Vane JR, Wyllie JH. Inactivation of prostaglandins by the lungs. Nature. 225: 600-4. PMID 4983971 DOI: 10.1038/225600A0  0.2
1970 Hughes J, Vane JR. Relaxations of the isolated portal vein of the rabbit induced by nicotine and electrical stimulation. British Journal of Pharmacology. 39: 476-89. PMID 4394338 DOI: 10.1111/j.1476-5381.1970.tb10356.x  0.297
1970 Gilore NJ, Vane JR. A sensitive and specific assay for vasopressin in the circulating blood. British Journal of Pharmacology. 38: 633-52. PMID 4392559 DOI: 10.1111/j.1476-5381.1970.tb09873.x  0.342
1970 Piper PJ, Said SI, Vane JR. Effects on smooth muscle preparations of unidentified vasoactiv peptides from intestine and lung. Nature. 225: 1144-6. PMID 4392130 DOI: 10.1038/2251144A0  0.223
1970 Aiken JW, Vane JR. The renin--angiotensin system: inhibition of converting enzyme in isolated tissues. Nature. 228: 30-4. PMID 4318494 DOI: 10.1038/228030A0  0.277
1970 Ng KK, Vane JR. Some properties of angiotensin converting enzyme in the lung in vivo. Nature. 225: 1142-4. PMID 4313869 DOI: 10.1038/2251142B0  0.228
1970 Ferreira SH, Greene LH, Alabaster VA, Bakhle YS, Vane JR. Activity of various fractions of bradykinin potentiating factor against angiotensin I converting enzyme. Nature. 225: 379-80. PMID 4312128 DOI: 10.1038/225379a0  0.257
1969 Ferreira SH, Gollub LR, Vane JR. The release of catecholamines by shocks and stimuli paired with shocks. Journal of the Experimental Analysis of Behavior. 12: 623-31. PMID 4980141 DOI: 10.1901/jeab.1969.12-623  0.282
1969 Vane JR. The dynamics of the renin-angiotensin system. Proceedings of the Royal Society of London. Series B, Biological Sciences. 173: 339-40. PMID 4389506 DOI: 10.1098/rspb.1969.0059  0.203
1969 Piper PJ, Vane JR. Release of additional factors in anaphylaxis and its antagonism by anti-inflammatory drugs. Nature. 223: 29-35. PMID 4389381 DOI: 10.1038/223029A0  0.282
1969 Vane JR. The release and fate of vaso-active hormones in the circulation. British Journal of Pharmacology. 35: 209-42. PMID 4388134 DOI: 10.1111/j.1476-5381.1969.tb07982.x  0.269
1969 Bakhle YS, Reynard AM, Vane JR. Metabolism of the angiotensins in isolated perfused tissues. Nature. 222: 956-9. PMID 4307046 DOI: 10.1038/222956A0  0.233
1969 Hodge RL, Lowe RD, Ng KK, Vane JR. Role of the vagus nerve in the control of the concentration of angiotensin II in the circulation. Nature. 221: 177-9. PMID 4302396 DOI: 10.1038/221177A0  0.223
1969 Pojda S, Vane J. The inhibition of bradykininases by trasylol in dog's blood Pharmacological Research Communications. 1: 186-187. DOI: 10.1016/S0031-6989(69)80105-0  0.303
1969 Berry H, Collier J, Vane J. Circulating kinins produced by blood loss in the dog Pharmacological Research Communications. 1: 139-140. DOI: 10.1016/S0031-6989(69)80059-7  0.27
1968 Ferreira SH, Vane JR. Prostaglandins: their disappearance from and release into the circulation. Nature. 216: 868-73. PMID 6074965 DOI: 10.1038/216868A0  0.285
1968 Ginn R, Vane JR. Disappearance of catecholamines from the circulation. Nature. 219: 740-2. PMID 5667070 DOI: 10.1038/219740A0  0.28
1968 Gilmore N, Vane JR, Wyllie JH. Prostaglandins released by the spleen. Nature. 218: 1135-40. PMID 5656636 DOI: 10.1038/2181135A0  0.274
1968 Marley E, Vane JR. Tryptamines and spinal cord reflexes in cats. British Journal of Pharmacology and Chemotherapy. 31: 447-65. PMID 5300182 DOI: 10.1111/J.1476-5381.1967.TB00411.X  0.166
1968 Bennett A, Friedmann CA, Vane JR. Release of prostaglandin E-1 from the rat stomach. Nature. 216: 873-6. PMID 4383761 DOI: 10.1038/216873A0  0.279
1968 Ng KK, Vane JR. The conversion of angiotensin I to angiotensin II in vivo. Naunyn-Schmiedebergs Archiv Fur Experimentelle Pathologie Und Pharmakologie. 259: 188-9. PMID 4298591 DOI: 10.1007/BF00537778  0.226
1968 Ng KK, Vane JR. Fate of angiotensin I in the circulation. Nature. 218: 144-50. PMID 4296306 DOI: 10.1038/218144A0  0.271
1968 Ng KK, Vane JR. Conversion of angiotensin I to angiotensin II. Nature. 216: 762-6. PMID 4294626 DOI: 10.1038/216762A0  0.215
1968 Duke HN, Vane JR. An adverse effect of polyvinylchloride tubing used in extracorporeal circulation. Lancet (London, England). 2: 21-3. PMID 4172686 DOI: 10.1016/S0140-6736(68)92891-2  0.233
1967 Hearst E, Vane JR. Some effects of d-amphetamine on the behavior of pigeons under intermittent reinforcement. Psychopharmacologia. 12: 58-67. PMID 6081328 DOI: 10.1007/BF00402755  0.186
1967 Thomas DP, Vane JR. 5-hydroxytryptamine in the circulation of the dog. Nature. 216: 335-8. PMID 6053807 DOI: 10.1038/216335a0  0.243
1967 Ferreira SH, Vane JR. The disappearance of bradykinin and eledoisin in the circulation and vascular beds of the cat. British Journal of Pharmacology and Chemotherapy. 30: 417-24. PMID 6036419 DOI: 10.1111/J.1476-5381.1967.TB02148.X  0.255
1967 Ferreira SH, Vane JR. The detection and estimation of bradykinin in the circulating blood. British Journal of Pharmacology and Chemotherapy. 29: 367-77. PMID 4382328 DOI: 10.1111/J.1476-5381.1967.TB01968.X  0.245
1967 Mikos E, Vane JR. Effects of gastrin and its analogues on isolated smooth muscles. Nature. 214: 105-7. PMID 4382269 DOI: 10.1038/214105A0  0.231
1967 Smith DJ, Vane JR. Effects of oxygen tension on vascular and other smooth muscle. The Journal of Physiology. 186: 284-94. PMID 4382029 DOI: 10.1113/jphysiol.1966.sp008034  0.289
1967 Ferreira SH, Vane JR. Half-lives of peptides and amines in the circulation. Nature. 215: 1237-40. PMID 4293215 DOI: 10.1038/2151237A0  0.195
1967 Staszewska-Barczak J, Vane JR. The release of catecholamines from the adrenal medulla by peptides. British Journal of Pharmacology and Chemotherapy. 30: 655-67. PMID 4292940 DOI: 10.1111/J.1476-5381.1967.TB02172.X  0.238
1967 Brown JJ, Lever AF, Robertson JI, Hodge RL, Lowe RD, Vane JR. Concurrent measurement of renin and angiotensin in the circulation of the dog. Nature. 215: 853-5. PMID 4292863 DOI: 10.1038/215853A0  0.256
1967 Hodge RL, Ng KK, Vane JR. Disappearance of angiotensin from the circulation of the dog. Nature. 215: 138-41. PMID 4292807 DOI: 10.1038/215138A0  0.27
1967 Hodge RL, Lowe RD, Vane JR. Increased angiotensin formation in response to carotid occlusion in the dog. Nature. 211: 491-3. PMID 4290896 DOI: 10.1038/211491A0  0.263
1966 Staszewska-Barczak J, Vane JR. The release of catechol amines from the adrenal medulla by histamine. British Journal of Pharmacology and Chemotherapy. 25: 728-42. PMID 4380600 DOI: 10.1111/J.1476-5381.1965.TB01795.X  0.272
1966 Regoli D, Vane JR. The continuous estimation of angiotensin formed in the circulation of the dog. The Journal of Physiology. 183: 513-31. PMID 4288294 DOI: 10.1113/jphysiol.1966.sp007881  0.338
1966 Hodge RL, Lowe RD, Vane JR. The effects of alteration of blood-volume on the concentration of circulating angiotensin in anaesthetized dogs. The Journal of Physiology. 185: 613-26. PMID 4288206 DOI: 10.1113/jphysiol.1966.sp008005  0.302
1965 Sewing K-, Born GVR, Vane JR. Differences in the actions of histamine, gastrin and a related tetrapeptide on gastric secretion in cats Naunyn-Schmiedeberg's Archiv F�R Experimentelle Pathologie Und Pharmakologie. 251: 181-182. DOI: 10.1007/BF00420153  0.237
1963 MARLEY E, VANE JR. Tryptamine Receptors in the Central Nervous System: Effects of Anæsthetics Nature. 198: 441-444. DOI: 10.1038/198441B0  0.206
1962 VANE JR, COLLIER HOJ, CORNE SJ, MARLEY E, BRADLEY PB. Tryptamine and Serotonin Receptors Nature. 194: 486-487. DOI: 10.1038/194486b0  0.2
1961 CLARK CG, VANE JR. The cardiac sphincter in the cat Gut. 2: 252-262. PMID 13879670 DOI: 10.1136/gut.2.3.252  0.184
1956 DAWES GS, VANE JR. The refractory period of atria isolated from mammalian hearts. The Journal of Physiology. 132: 611-29. PMID 13332598  0.481
1956 BARLOW RB, VANE JR. The ganglion-blocking properties of hexamethylene bisdialkylsulphonium salts. British Journal of Pharmacology and Chemotherapy. 11: 198-201. PMID 13329339 DOI: 10.1111/J.1476-5381.1956.TB01053.X  0.212
1953 BORN GV, VANE JR. Gastric secretion induced by histamine. The Journal of Physiology. 121: 445-51. PMID 13097384  0.51
1953 DAWES GS, MOTT JC, VANE JR. The density flowmeter, a direct method for the measurement of the rate of blood flow. The Journal of Physiology. 121: 72-9. PMID 13085300  0.492
1953 Thompson JE, Vane JR. Gastric secretion induced by histamine and its relationship to the rate of blood flow The Journal of Physiology. 121: 433-444. DOI: 10.1113/jphysiol.1953.sp004956  0.274
1952 BORN GV, VANE JR. The quantitative determination of diffusible histamine in blood. British Journal of Pharmacology and Chemotherapy. 7: 298-303. PMID 14954128  0.499
1952 Vane JR, Thompson JE. Experimental studies of gastric blood flow: Preliminary report Angiology. 3: 179-184. DOI: 10.1177/000331975200300204  0.278
1949 BURN JH, VANE JR. The relation between the motor and inhibitor actions of acetylcholine. The Journal of Physiology. 108: 104-15. PMID 18128151 DOI: 10.1113/jphysiol.1949.sp004314  0.596
1948 VANE JR, WALKER JM, PARRY CB. The effect of paludrine on gastric secretion in man. British Journal of Pharmacology and Chemotherapy. 3: 350. PMID 18102607 DOI: 10.1111/J.1476-5381.1948.TB00400.X  0.235
1948 BURN JH, VANE JR. The inhibitory action of paludrine on the secretion of gastric juice. British Journal of Pharmacology and Chemotherapy. 3: 346-9. PMID 18102606  0.605
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