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William Dampier, Ph.D. - Publications

Affiliations: 
2010 Drexel University, Philadelphia, PA, United States 
Area:
Biomedical Engineering
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33 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2020 Sullivan NT, Allen AG, Atkins AJ, Chung CH, Dampier W, Nonnemacher MR, Wigdahl B. Designing Safer CRISPR/Cas9 Therapeutics for HIV: Defining Factors That Regulate and Technologies Used to Detect Off-Target Editing. Frontiers in Microbiology. 11: 1872. PMID 32903440 DOI: 10.3389/Fmicb.2020.01872  0.478
2020 Chung CH, Allen AG, Atkins AJ, Sullivan NT, Homan G, Costello R, Madrid R, Nonnemacher MR, Dampier W, Wigdahl B. Safe CRISPR-Cas9 Inhibition of HIV-1 with High Specificity and Broad-Spectrum Activity by Targeting LTR NF-κB Binding Sites. Molecular Therapy. Nucleic Acids. 21: 965-982. PMID 32818921 DOI: 10.1016/J.Omtn.2020.07.016  0.524
2020 Mele AR, Marino J, Dampier W, Wigdahl B, Nonnemacher MR. HIV-1 Tat Length: Comparative and Functional Considerations. Frontiers in Microbiology. 11: 444. PMID 32265877 DOI: 10.3389/Fmicb.2020.00444  0.488
2019 Sullivan NT, Dampier W, Chung CH, Allen AG, Atkins A, Pirrone V, Homan G, Passic S, Williams J, Zhong W, Kercher K, Desimone M, Li L, C Antell G, Mell JC, et al. Novel gRNA design pipeline to develop broad-spectrum CRISPR/Cas9 gRNAs for safe targeting of the HIV-1 quasispecies in patients. Scientific Reports. 9: 17088. PMID 31745112 DOI: 10.1038/S41598-019-52353-9  0.545
2019 Chung CH, Allen AG, Sullivan NT, Atkins A, Nonnemacher MR, Wigdahl B, Dampier W. Computational Analysis Concerning the Impact of DNA Accessibility on CRISPR-Cas9 Cleavage Efficiency. Molecular Therapy : the Journal of the American Society of Gene Therapy. PMID 31672284 DOI: 10.1016/J.Ymthe.2019.10.008  0.301
2019 Link RW, Mele AR, Antell GC, Pirrone V, Zhong W, Kercher K, Passic S, Szep Z, Malone K, Jacobson JM, Dampier W, Wigdahl B, Nonnemacher MR. Investigating the distribution of HIV-1 Tat lengths present in the Drexel Medicine CARES cohort. Virus Research. 197727. PMID 31437485 DOI: 10.1016/J.Virusres.2019.197727  0.427
2019 Wigdahl B, Allen A, Worell S, Nwaozo G, Madrid R, Dampier W, Nonnemacher M. Broad-spectrum gRNAs abolish HIV-1 LTR-mediated transcription in cells that receive CRISPR/Cas9 therapy Journal of Virus Eradication. 5: 54. DOI: 10.1016/S2055-6640(20)30217-X  0.47
2018 Allen AG, Chung CH, Atkins A, Dampier W, Khalili K, Nonnemacher MR, Wigdahl B. Gene Editing of HIV-1 Co-receptors to Prevent and/or Cure Virus Infection. Frontiers in Microbiology. 9: 2940. PMID 30619107 DOI: 10.3389/Fmicb.2018.02940  0.529
2018 Dampier W, Sullivan NT, Mell J, Pirrone V, Ehrlich G, Chung CH, Allen AG, DeSimone M, Zhong W, Kercher K, Passic S, Williams J, Szep Z, Khalili K, Jacobson J, et al. Broad spectrum and personalized gRNAs for CRISPR/Cas9 HIV-1 therapeutics. Aids Research and Human Retroviruses. PMID 29968495 DOI: 10.1089/Aid.2017.0274  0.526
2018 Mumford B, Pirrone V, O’Hayer CV, Dampier W, Wigdahl B, O’Loughlin C, Amat M, Szep Z. 584. Investigation of the Association Between Neurocognitive Function and Depression in HIV Infection Open Forum Infectious Diseases. 5: S215-S215. DOI: 10.1093/Ofid/Ofy210.591  0.43
2017 Dampier W, Sullivan NT, Chung CH, Mell JC, Nonnemacher MR, Wigdahl B. Designing broad-spectrum anti-HIV-1 gRNAs to target patient-derived variants. Scientific Reports. 7: 14413. PMID 29089503 DOI: 10.1038/S41598-017-12612-Z  0.528
2017 Antell GC, Dampier W, Aiamkitsumrit B, Nonnemacher MR, Pirrone V, Zhong W, Kercher K, Passic S, Williams J, Liu Y, James T, Jacobson JM, Szep Z, Wigdahl B, Krebs FC. Evidence of Divergent Amino Acid Usage in Comparative Analyses of R5- and X4-Associated HIV-1 Vpr Sequences. International Journal of Genomics. 2017: 4081585. PMID 28620613 DOI: 10.1155/2017/4081585  0.473
2017 Allen A, Sullivan NT, Dampier W, Chung CH, Atkins A, Homan G, Pirrone V, Passic S, Williams J, Szep Z, Jacobson JM, Nonnemacher MR, Wigdahl B. Designing broad-spectrum gRNAs to target the HIV-1 LTR with CRISPR/cas9-based therapeutic strategies Journal of Virus Eradication. 3: 50. DOI: 10.1016/S2055-6640(20)30669-5  0.46
2017 Nonnemacher MR, Mele AR, King KM, Antell G, Dampier W, Tata R, Pirrone V, Williams J, Homan G, Passic S, Kercher K, Zhong W, Szep Z, Jacobson J, Wigdahl B, et al. Examining functional alterations of HIV-1 Tat variants associated with neurocognitively impaired patients in the Drexel Medicine CARES Cohort Journal of Virus Eradication. 3: 24. DOI: 10.1016/S2055-6640(20)30624-5  0.446
2016 Azar A, Devlin K, Mell JC, Giovannetti T, Pirrone V, Nonnemacher MR, Passic S, Kercher K, Williams JW, Jacobson JM, Wigdahl B, Dampier W, Libon DJ, Sell C. Mitochondrial Haplogroup Influences Motor Function in Long-Term HIV-1-Infected Individuals. Plos One. 11: e0163772. PMID 27711166 DOI: 10.1016/J.Exger.2017.02.027  0.414
2016 Dampier W, Antell GC, Aiamkitsumrit B, Nonnemacher MR, Jacobson JM, Pirrone V, Zhong W, Kercher K, Passic S, Williams JW, James T, Devlin KN, Giovannetti T, Libon DJ, Szep Z, et al. Specific amino acids in HIV-1 Vpr are significantly associated with differences in patient neurocognitive status. Journal of Neurovirology. PMID 27400931 DOI: 10.1007/S13365-016-0462-3  0.511
2016 Dampier W, Nonnemacher MR, Mell J, Earl J, Ehrlich GD, Pirrone V, Aiamkitsumrit B, Zhong W, Kercher K, Passic S, Williams JW, Jacobson JM, Wigdahl B. HIV-1 Genetic Variation Resulting in the Development of New Quasispecies Continues to Be Encountered in the Peripheral Blood of Well-Suppressed Patients. Plos One. 11: e0155382. PMID 27195985 DOI: 10.1371/Journal.Pone.0155382  0.49
2016 Antell GC, Dampier W, Aiamkitsumrit B, Nonnemacher MR, Jacobson JM, Pirrone V, Zhong W, Kercher K, Passic S, Williams JW, Schwartz G, Hershberg U, Krebs FC, Wigdahl B. Utilization of HIV-1 envelope V3 to identify X4- and R5-specific Tat and LTR sequence signatures. Retrovirology. 13: 32. PMID 27143130 DOI: 10.1186/S12977-016-0266-9  0.472
2016 Nonnemacher MR, Pirrone V, Feng R, Moldover B, Passic S, Aiamkitsumrit B, Dampier W, Wojno A, Kilareski E, Blakey B, Ku TS, Shah S, Sullivan NT, Jacobson JM, Wigdahl B. HIV-1 Promoter Single Nucleotide Polymorphisms Are Associated with Clinical Disease Severity. Plos One. 11: e0150835. PMID 27100290 DOI: 10.1371/Journal.Pone.0150835  0.459
2016 Datta PK, Kaminski R, Hu W, Pirrone V, Sullivan NT, Nonnemacher MR, Dampier W, Wigdahl B, Khalili K. HIV-1 Latency and Eradication: Past, Present and Future. Current Hiv Research. PMID 27009094 DOI: 10.2174/1570162X14666160324125536  0.514
2015 Sullivan NT, Nonnemacher MR, Pirrone V, Feng R, Moldover B, Dampier W, Passic S, Williams J, Aiamkitsumrit B, Zhong W, Blakey B, Shah S, Jacobson JM, Wigdahl B. SNPs within the HIV-1 LTR associate with increased virus persistence Journal of Virus Eradication. 1: 26. DOI: 10.1016/S2055-6640(20)31384-4  0.46
2015 Dampier W, Nonnemacher MR, Mell JC, Earl J, Pirrone V, Aiamkitsumrit B, Zhong W, Kercher K, Passic S, Williams JW, Jacobson JM, Wigdahl B. Genetic variation continues to occur in well-controlled HIV-1-infected patients Journal of Virus Eradication. 1: 42. DOI: 10.1016/S2055-6640(20)31349-2  0.447
2015 Nonnemacher M, Dampier W, Desimone M, Pirrone V, Kercher K, Passic S, Williams J, Wigdahl B. Utilizing the binding capacity of CRISPR/Cas9 to target the HIV-1 quasispecies Journal of Virus Eradication. 1: 42. DOI: 10.1016/S2055-6640(20)31347-9  0.473
2014 Dampier W, Nonnemacher MR, Sullivan NT, Jacobson JM, Wigdahl B. HIV Excision Utilizing CRISPR/Cas9 Technology: Attacking the Proviral Quasispecies in Reservoirs to Achieve a Cure. Moj Immunology. 1. PMID 25893217 DOI: 10.15406/Moji.2014.01.00022  0.533
2014 Aiamkitsumrit B, Dampier W, Martin-Garcia J, Nonnemacher MR, Pirrone V, Ivanova T, Zhong W, Kilareski E, Aldigun H, Frantz B, Rimbey M, Wojno A, Passic S, Williams JW, Shah S, et al. Defining differential genetic signatures in CXCR4- and the CCR5-utilizing HIV-1 co-linear sequences. Plos One. 9: e107389. PMID 25265194 DOI: 10.1371/Journal.Pone.0107389  0.434
2014 Aiamkitsumrit B, Dampier W, Antell G, Rivera N, Martin-Garcia J, Pirrone V, Nonnemacher MR, Wigdahl B. Bioinformatic analysis of HIV-1 entry and pathogenesis. Current Hiv Research. 12: 132-61. PMID 24862329 DOI: 10.2174/1570162X12666140526121746  0.494
2014 Parikh N, Dampier W, Feng R, Passic SR, Zhong W, Frantz B, Blakey B, Aiamkitsumrit B, Pirrone V, Nonnemacher MR, Jacobson JM, Wigdahl B. Cocaine alters cytokine profiles in HIV-1-infected African American individuals in the DrexelMed HIV/AIDS genetic analysis cohort. Journal of Acquired Immune Deficiency Syndromes (1999). 66: 256-64. PMID 24732878 DOI: 10.1097/Qai.0000000000000163  0.456
2014 Dahiya S, Liu Y, Nonnemacher MR, Dampier W, Wigdahl B. CCAAT enhancer binding protein and nuclear factor of activated T cells regulate HIV-1 LTR via a novel conserved downstream site in cells of the monocyte-macrophage lineage. Plos One. 9: e88116. PMID 24551078 DOI: 10.1371/Journal.Pone.0088116  0.44
2011 Sarmady M, Dampier W, Tozeren A. HIV protein sequence hotspots for crosstalk with host hub proteins. Plos One. 6: e23293. PMID 21858059 DOI: 10.1371/Journal.Pone.0023293  0.51
2011 Sarmady M, Dampier W, Tozeren A. Sequence- and interactome-based prediction of viral protein hotspots targeting host proteins: a case study for HIV Nef. Plos One. 6: e20735. PMID 21738584 DOI: 10.1371/Journal.Pone.0020735  0.4
2010 Zhou J, Wang C, Wang Z, Dampier W, Wu K, Casimiro MC, Chepelev I, Popov VM, Quong A, Tozeren A, Zhao K, Lisanti MP, Pestell RG. Attenuation of Forkhead signaling by the retinal determination factor DACH1 Proceedings of the National Academy of Sciences of the United States of America. 107: 6864-6869. PMID 20351289 DOI: 10.1073/Pnas.1002746107  0.326
2009 Dampier W, Evans P, Ungar L, Tozeren A. Host sequence motifs shared by HIV predict response to antiretroviral therapy. Bmc Medical Genomics. 2: 47. PMID 19627600 DOI: 10.1186/1755-8794-2-47  0.451
2009 Evans P, Dampier W, Ungar L, Tozeren A. Prediction of HIV-1 virus-host protein interactions using virus and host sequence motifs. Bmc Medical Genomics. 2: 27. PMID 19450270 DOI: 10.1186/1755-8794-2-27  0.322
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