C Roskelley - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Cell Biology, Oncology, Molecular Biology

46 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2022 Santos M, Ferreira M, Oliveira P, Mendes N, André A, Vieira AF, Nunes JB, Carvalho J, Rocha S, Azevedo M, Ferreira D, Reis I, Vinagre J, Paredes J, Heravi-Moussavi A, ... ... Roskelley C, et al. Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFβ1 Promotes Tumour Growth. Biology. 11. PMID 36101425 DOI: 10.3390/biology11071046  0.433
2022 Bell EM, Graves ML, Dean PM, Goodman TO, Roskelley CD. Modeling Collective Invasion and Single-Cell Mesenchymal Invasion in Three-Dimensional Matrigel-Collagen I Cultures. Methods in Molecular Biology (Clifton, N.J.). 2508: 79-99. PMID 35737235 DOI: 10.1007/978-1-0716-2376-3_8  0.302
2016 Graves ML, Cipollone JA, Austin P, Bell EM, Nielsen JS, Gilks CB, McNagny KM, Roskelley CD. The cell surface mucin podocalyxin regulates collective breast tumor budding. Breast Cancer Research : Bcr. 18: 11. PMID 26796961 DOI: 10.1186/s13058-015-0670-4  0.336
2015 Duminuco R, Noble JW, Goody J, Sharma M, Ksander BR, Roskelley CD, Cox ME, Mills J. Integrin-Linked Kinase Regulates Senescence in an Rb-Dependent Manner in Cancer Cell Lines. Cell Cycle (Georgetown, Tex.). 0. PMID 26176204 DOI: 10.1080/15384101.2015.1064205  0.316
2015 Snyder KA, Hughes MR, Hedberg B, Brandon J, Hernaez DC, Bergqvist P, Cruz F, Po K, Graves ML, Turvey ME, Nielsen JS, Wilkins JA, McColl SR, Babcook JS, Roskelley CD, et al. Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy. Breast Cancer Research : Bcr. 17: 46. PMID 25887862 DOI: 10.1186/s13058-015-0562-7  0.312
2013 Austin P, Freeman SA, Gray CA, Gold MR, Vogl AW, Andersen RJ, Roberge M, Roskelley CD. The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner. Molecular Cancer Research : McR. 11: 530-40. PMID 23399642 DOI: 10.1158/1541-7786.Mcr-12-0385  0.438
2013 Zimmerman C, Austin P, Khong A, McLeod S, Bean B, Forestieri R, Andersen RJ, Jan E, Roberge M, Roskelley CD. The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility. Experimental Cell Research. 319: 908-17. PMID 23333560 DOI: 10.1016/J.Yexcr.2013.01.005  0.367
2013 Lymburner S, McLeod S, Purtzki M, Roskelley C, Xu Z. Zinc inhibits magnesium-dependent migration of human breast cancer MDA-MB-231 cells on fibronectin. The Journal of Nutritional Biochemistry. 24: 1034-40. PMID 23026493 DOI: 10.1016/j.jnutbio.2012.07.013  0.374
2012 Onishi I, Lin PJ, Numata Y, Austin P, Cipollone J, Roberge M, Roskelley CD, Numata M. Organellar (Na+, K+)/H+ exchanger NHE7 regulates cell adhesion, invasion and anchorage-independent growth of breast cancer MDA-MB-231 cells. Oncology Reports. 27: 311-7. PMID 22076128 DOI: 10.3892/or.2011.1542  0.364
2011 Lou Y, McDonald PC, Oloumi A, Chia S, Ostlund C, Ahmadi A, Kyle A, Auf dem Keller U, Leung S, Huntsman D, Clarke B, Sutherland BW, Waterhouse D, Bally M, Roskelley C, et al. Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Research. 71: 3364-76. PMID 21415165 DOI: 10.1158/0008-5472.Can-10-4261  0.325
2011 Tognon CE, Somasiri AM, Evdokimova VE, Trigo G, Uy EE, Melnyk N, Carboni JM, Gottardis MM, Roskelley CD, Pollak M, Sorensen PH. ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway. Cancer Research. 71: 1060-70. PMID 21148487 DOI: 10.1158/0008-5472.Can-10-3096  0.717
2010 Freeman SA, McLeod SJ, Dukowski J, Austin P, Lee CC, Millen-Martin B, Kubes P, McCafferty DM, Gold MR, Roskelley CD. Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs. Cancer Research. 70: 4590-601. PMID 20484042 DOI: 10.1158/0008-5472.CAN-09-3414  0.349
2008 Lou Y, Preobrazhenska O, auf dem Keller U, Sutcliffe M, Barclay L, McDonald PC, Roskelley C, Overall CM, Dedhar S. Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2755-68. PMID 18773493 DOI: 10.1002/Dvdy.21658  0.43
2008 Wu C, Cipollone J, Maines-Bandiera S, Tan C, Karsan A, Auersperg N, Roskelley CD. The morphogenic function of E-cadherin-mediated adherens junctions in epithelial ovarian carcinoma formation and progression. Differentiation; Research in Biological Diversity. 76: 193-205. PMID 17608733 DOI: 10.1111/J.1432-0436.2007.00193.X  0.408
2006 Krubasik D, Iyer NG, English WR, Ahmed AA, Vias M, Roskelley C, Brenton JD, Caldas C, Murphy G. Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition. British Journal of Cancer. 94: 1326-32. PMID 16622451 DOI: 10.1038/sj.bjc.6603101  0.36
2005 Filipenko NR, Attwell S, Roskelley C, Dedhar S. Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX. Oncogene. 24: 5837-49. PMID 15897874 DOI: 10.1038/Sj.Onc.1208737  0.329
2005 McHardy LM, Warabi K, Andersen RJ, Roskelley CD, Roberge M. Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Molecular Cancer Therapeutics. 4: 772-8. PMID 15897241 DOI: 10.1158/1535-7163.Mct-04-0310  0.314
2004 Wong AS, Roskelley CD, Pelech S, Miller D, Leung PC, Auersperg N. Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation. Experimental Cell Research. 299: 248-56. PMID 15302591 DOI: 10.1016/j.yexcr.2004.06.002  0.324
2004 Somasiri A, Nielsen JS, Makretsov N, McCoy ML, Prentice L, Gilks CB, Chia SK, Gelmon KA, Kershaw DB, Huntsman DG, McNagny KM, Roskelley CD. Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Research. 64: 5068-73. PMID 15289306 DOI: 10.1158/0008-5472.Can-04-0240  0.716
2004 Maines-Bandiera SL, Huntsman D, Lestou VS, Kuo WL, Leung PC, Horsman RD, Wong AS, Woo MM, Choi KK, Roskelley CD, Auersperg N. Epithelio-mesenchymal transition in a neoplastic ovarian epithelial hybrid cell line. Differentiation; Research in Biological Diversity. 72: 150-61. PMID 15157238 DOI: 10.1111/j.1432-0436.2004.07204003.x  0.382
2004 McHardy LM, Sinotte R, Troussard A, Sheldon C, Church J, Williams DE, Andersen RJ, Dedhar S, Roberge M, Roskelley CD. The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Research. 64: 1468-74. PMID 14973060 DOI: 10.1158/0008-5472.Can-03-2733  0.308
2004 Ward KR, Zhang KX, Somasiri AM, Roskelley CD, Schrader JW. Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial-mesenchymal transition and tumorigenesis Oncogene. 23: 1187-1196. PMID 14961075 DOI: 10.1038/Sj.Onc.1207226  0.691
2004 Zand L, Qiang F, Roskelley CD, Leung PC, Auersperg N. Differential effects of cellular fibronectin and plasma fibronectin on ovarian cancer cell adhesion, migration, and invasion. In Vitro Cellular & Developmental Biology. Animal. 39: 178-82. PMID 14505428 DOI: 10.1007/s11626-003-0013-0  0.38
2003 Novaro V, Roskelley CD, Bissell MJ. Collagen-IV and laminin-1 regulate estrogen receptor α expression and function in mouse mammary epithelial cells Journal of Cell Science. 116: 2975-2986. PMID 12808020 DOI: 10.1242/Jcs.00523  0.324
2002 Tognon C, Knezevich SR, Huntsman D, Roskelley CD, Melnyk N, Mathers JA, Becker L, Carneiro F, MacPherson N, Horsman D, Poremba C, Sorensen PH. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell. 2: 367-76. PMID 12450792 DOI: 10.1016/S1535-6108(02)00180-0  0.373
2001 Roskelley CD, Williams DE, McHardy LM, Leong KG, Troussard A, Karsan A, Andersen RJ, Dedhar S, Roberge M. Inhibition of tumor cell invasion and angiogenesis by motuporamines. Cancer Research. 61: 6788-94. PMID 11559552  0.344
2001 Somasiri A, Howarth A, Goswami D, Dedhar S, Roskelley CD. Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells. Journal of Cell Science. 114: 1125-36. PMID 11228156  0.358
2001 Somasiri A, Wu C, Ellchuk T, Turley S, Roskelley CD. Phosphatidylinositol 3-kinase is required for adherens junction-dependent mammary epithelial cell spheroid formation. Differentiation; Research in Biological Diversity. 66: 116-25. PMID 11100902 DOI: 10.1046/J.1432-0436.2000.660206.X  0.724
2000 Attwell S, Roskelley C, Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene. 19: 3811-5. PMID 10949937 DOI: 10.1038/Sj.Onc.1203711  0.363
2000 Roskelley CD, Wu C, Somasiri AM. Analysis of mammary gland morphogenesis. Methods in Molecular Biology (Clifton, N.J.). 136: 27-38. PMID 10840694 DOI: 10.1385/1-59259-065-9:27  0.678
2000 Ong A, Maines-Bandiera SL, Roskelley CD, Auersperg N. An ovarian adenocarcinoma line derived from SV40/E-cadherin-transfected normal human ovarian surface epithelium. International Journal of Cancer. 85: 430-7. PMID 10652437 DOI: 10.1002/(SICI)1097-0215(20000201)85:3<430::AID-IJC21>3.0.CO;2-Q  0.397
1999 Somasiri A, Roskelley CD. Cell shape and integrin signaling regulate the differentiation state of mammary epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 129: 271-83. PMID 10494571 DOI: 10.1385/1-59259-249-X:271  0.714
1999 Muschler J, Lochter A, Roskelley CD, Yurchenco P, Bissell MJ. Division of labor among the α6β4 integrin, β1 integrins, and an E3 laminin receptor to signal morphogenesis and β-casein expression in mammary epithelial cells Molecular Biology of the Cell. 10: 2817-2828. PMID 10473629 DOI: 10.1091/Mbc.10.9.2817  0.322
1999 Auersperg N, Pan J, Grove BD, Peterson T, Fisher J, Maines-Bandiera S, Somasiri A, Roskelley CD. E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium Proceedings of the National Academy of Sciences of the United States of America. 96: 6249-6254. PMID 10339573 DOI: 10.1073/Pnas.96.11.6249  0.719
1999 Wong AS, Maines-Bandiera SL, Rosen B, Wheelock MJ, Johnson KR, Leung PC, Roskelley CD, Auersperg N. Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: influence of family history of ovarian cancer. International Journal of Cancer. 81: 180-8. PMID 10188716 DOI: 10.1002/(Sici)1097-0215(19990412)81:2<180::Aid-Ijc3>3.0.Co;2-7  0.305
1998 Novak A, Hsu SC, Leung-Hagesteijn C, Radeva G, Papkoff J, Montesano R, Roskelley C, Grosschedl R, Dedhar S. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways Proceedings of the National Academy of Sciences of the United States of America. 95: 4374-4379. PMID 9539744 DOI: 10.1073/Pnas.95.8.4374  0.32
1997 Close MJ, Howlett AR, Roskelley CD, Desprez PY, Bailey N, Rowning B, Teng CT, Stampfer MR, Yaswen P. Lactoferrin expression in mammary epithelial cells is mediated by changes in cell shape and actin cytoskeleton. Journal of Cell Science. 110: 2861-71. PMID 9427294  0.398
1996 Roskelley CD, Bissell MJ. Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 391-7. PMID 8703411 DOI: 10.1139/O95-046  0.314
1996 Roskelley CD, Auersperg N. Rapid ras-oncogene-mediated transformation maintains steroidogenic differentiation in adrenocortical parenchymal cells. Differentiation; Research in Biological Diversity. 59: 103-11. PMID 8522067 DOI: 10.1046/j.1432-0436.1995.5920103.x  0.355
1995 Streuli CH, Schmidhauser C, Bailey N, Yurchenco P, Skubitz AP, Roskelley C, Bissell MJ. Laminin mediates tissue-specific gene expression in mammary epithelia. The Journal of Cell Biology. 129: 591-603. PMID 7730398 DOI: 10.1083/Jcb.129.3.591  0.305
1995 Pan J, Roskelley CD, Auersperg N. Influence of cell type on the steroidogenic potential and basal cyclic AMP levels of ras-oncogene-transformed rat cells. Differentiation; Research in Biological Diversity. 58: 321-8. PMID 7622009 DOI: 10.1046/j.1432-0436.1995.5850321.x  0.387
1995 Roskelley CD, Desprez PY, Bissell MJ. Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 91: 12378-82. PMID 7528920 DOI: 10.1073/Pnas.91.26.12378  0.355
1994 Roskelley C, Auersperg N. Mixed parenchymal-stromal populations of rat adrenocortical cells support the proliferation and differentiation of steroidogenic cells. Differentiation; Research in Biological Diversity. 55: 37-45. PMID 8299879 DOI: 10.1111/j.1432-0436.1993.tb00031.x  0.36
1992 Pan J, Roskelley CD, Luu-The V, Rojiani M, Auersperg N. Reversal of divergent differentiation by ras oncogene-mediated transformation. Cancer Research. 52: 4269-72. PMID 1379124  0.397
1991 Auersperg N, Roskelley C. Retroviral oncogenes: interrelationships between neoplastic transformation and cell differentiation. Critical Reviews in Oncogenesis. 2: 125-60. PMID 1854833  0.314
1990 Roskelley CD, Auersperg N. Density separation of rat adrenocortical cells: morphology, steroidogenesis, and P-450scc expression in primary culture. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 26: 493-501. PMID 2161828 DOI: 10.1007/BF02624091  0.34
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