Year |
Citation |
Score |
2022 |
Santos M, Ferreira M, Oliveira P, Mendes N, André A, Vieira AF, Nunes JB, Carvalho J, Rocha S, Azevedo M, Ferreira D, Reis I, Vinagre J, Paredes J, Heravi-Moussavi A, ... ... Roskelley C, et al. Epithelial-Mesenchymal Plasticity Induced by Discontinuous Exposure to TGFβ1 Promotes Tumour Growth. Biology. 11. PMID 36101425 DOI: 10.3390/biology11071046 |
0.433 |
|
2022 |
Bell EM, Graves ML, Dean PM, Goodman TO, Roskelley CD. Modeling Collective Invasion and Single-Cell Mesenchymal Invasion in Three-Dimensional Matrigel-Collagen I Cultures. Methods in Molecular Biology (Clifton, N.J.). 2508: 79-99. PMID 35737235 DOI: 10.1007/978-1-0716-2376-3_8 |
0.302 |
|
2016 |
Graves ML, Cipollone JA, Austin P, Bell EM, Nielsen JS, Gilks CB, McNagny KM, Roskelley CD. The cell surface mucin podocalyxin regulates collective breast tumor budding. Breast Cancer Research : Bcr. 18: 11. PMID 26796961 DOI: 10.1186/s13058-015-0670-4 |
0.336 |
|
2015 |
Duminuco R, Noble JW, Goody J, Sharma M, Ksander BR, Roskelley CD, Cox ME, Mills J. Integrin-Linked Kinase Regulates Senescence in an Rb-Dependent Manner in Cancer Cell Lines. Cell Cycle (Georgetown, Tex.). 0. PMID 26176204 DOI: 10.1080/15384101.2015.1064205 |
0.316 |
|
2015 |
Snyder KA, Hughes MR, Hedberg B, Brandon J, Hernaez DC, Bergqvist P, Cruz F, Po K, Graves ML, Turvey ME, Nielsen JS, Wilkins JA, McColl SR, Babcook JS, Roskelley CD, et al. Podocalyxin enhances breast tumor growth and metastasis and is a target for monoclonal antibody therapy. Breast Cancer Research : Bcr. 17: 46. PMID 25887862 DOI: 10.1186/s13058-015-0562-7 |
0.312 |
|
2013 |
Austin P, Freeman SA, Gray CA, Gold MR, Vogl AW, Andersen RJ, Roberge M, Roskelley CD. The invasion inhibitor sarasinoside A1 reverses mesenchymal tumor transformation in an E-cadherin-independent manner. Molecular Cancer Research : McR. 11: 530-40. PMID 23399642 DOI: 10.1158/1541-7786.Mcr-12-0385 |
0.438 |
|
2013 |
Zimmerman C, Austin P, Khong A, McLeod S, Bean B, Forestieri R, Andersen RJ, Jan E, Roberge M, Roskelley CD. The small molecule genkwanine M induces single mode, mesenchymal tumor cell motility. Experimental Cell Research. 319: 908-17. PMID 23333560 DOI: 10.1016/J.Yexcr.2013.01.005 |
0.367 |
|
2013 |
Lymburner S, McLeod S, Purtzki M, Roskelley C, Xu Z. Zinc inhibits magnesium-dependent migration of human breast cancer MDA-MB-231 cells on fibronectin. The Journal of Nutritional Biochemistry. 24: 1034-40. PMID 23026493 DOI: 10.1016/j.jnutbio.2012.07.013 |
0.374 |
|
2012 |
Onishi I, Lin PJ, Numata Y, Austin P, Cipollone J, Roberge M, Roskelley CD, Numata M. Organellar (Na+, K+)/H+ exchanger NHE7 regulates cell adhesion, invasion and anchorage-independent growth of breast cancer MDA-MB-231 cells. Oncology Reports. 27: 311-7. PMID 22076128 DOI: 10.3892/or.2011.1542 |
0.364 |
|
2011 |
Lou Y, McDonald PC, Oloumi A, Chia S, Ostlund C, Ahmadi A, Kyle A, Auf dem Keller U, Leung S, Huntsman D, Clarke B, Sutherland BW, Waterhouse D, Bally M, Roskelley C, et al. Targeting tumor hypoxia: suppression of breast tumor growth and metastasis by novel carbonic anhydrase IX inhibitors. Cancer Research. 71: 3364-76. PMID 21415165 DOI: 10.1158/0008-5472.Can-10-4261 |
0.325 |
|
2011 |
Tognon CE, Somasiri AM, Evdokimova VE, Trigo G, Uy EE, Melnyk N, Carboni JM, Gottardis MM, Roskelley CD, Pollak M, Sorensen PH. ETV6-NTRK3-mediated breast epithelial cell transformation is blocked by targeting the IGF1R signaling pathway. Cancer Research. 71: 1060-70. PMID 21148487 DOI: 10.1158/0008-5472.Can-10-3096 |
0.717 |
|
2010 |
Freeman SA, McLeod SJ, Dukowski J, Austin P, Lee CC, Millen-Martin B, Kubes P, McCafferty DM, Gold MR, Roskelley CD. Preventing the activation or cycling of the Rap1 GTPase alters adhesion and cytoskeletal dynamics and blocks metastatic melanoma cell extravasation into the lungs. Cancer Research. 70: 4590-601. PMID 20484042 DOI: 10.1158/0008-5472.CAN-09-3414 |
0.349 |
|
2008 |
Lou Y, Preobrazhenska O, auf dem Keller U, Sutcliffe M, Barclay L, McDonald PC, Roskelley C, Overall CM, Dedhar S. Epithelial-mesenchymal transition (EMT) is not sufficient for spontaneous murine breast cancer metastasis. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 237: 2755-68. PMID 18773493 DOI: 10.1002/Dvdy.21658 |
0.43 |
|
2008 |
Wu C, Cipollone J, Maines-Bandiera S, Tan C, Karsan A, Auersperg N, Roskelley CD. The morphogenic function of E-cadherin-mediated adherens junctions in epithelial ovarian carcinoma formation and progression. Differentiation; Research in Biological Diversity. 76: 193-205. PMID 17608733 DOI: 10.1111/J.1432-0436.2007.00193.X |
0.408 |
|
2006 |
Krubasik D, Iyer NG, English WR, Ahmed AA, Vias M, Roskelley C, Brenton JD, Caldas C, Murphy G. Absence of p300 induces cellular phenotypic changes characteristic of epithelial to mesenchyme transition. British Journal of Cancer. 94: 1326-32. PMID 16622451 DOI: 10.1038/sj.bjc.6603101 |
0.36 |
|
2005 |
Filipenko NR, Attwell S, Roskelley C, Dedhar S. Integrin-linked kinase activity regulates Rac- and Cdc42-mediated actin cytoskeleton reorganization via alpha-PIX. Oncogene. 24: 5837-49. PMID 15897874 DOI: 10.1038/Sj.Onc.1208737 |
0.329 |
|
2005 |
McHardy LM, Warabi K, Andersen RJ, Roskelley CD, Roberge M. Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions. Molecular Cancer Therapeutics. 4: 772-8. PMID 15897241 DOI: 10.1158/1535-7163.Mct-04-0310 |
0.314 |
|
2004 |
Wong AS, Roskelley CD, Pelech S, Miller D, Leung PC, Auersperg N. Progressive changes in Met-dependent signaling in a human ovarian surface epithelial model of malignant transformation. Experimental Cell Research. 299: 248-56. PMID 15302591 DOI: 10.1016/j.yexcr.2004.06.002 |
0.324 |
|
2004 |
Somasiri A, Nielsen JS, Makretsov N, McCoy ML, Prentice L, Gilks CB, Chia SK, Gelmon KA, Kershaw DB, Huntsman DG, McNagny KM, Roskelley CD. Overexpression of the anti-adhesin podocalyxin is an independent predictor of breast cancer progression. Cancer Research. 64: 5068-73. PMID 15289306 DOI: 10.1158/0008-5472.Can-04-0240 |
0.716 |
|
2004 |
Maines-Bandiera SL, Huntsman D, Lestou VS, Kuo WL, Leung PC, Horsman RD, Wong AS, Woo MM, Choi KK, Roskelley CD, Auersperg N. Epithelio-mesenchymal transition in a neoplastic ovarian epithelial hybrid cell line. Differentiation; Research in Biological Diversity. 72: 150-61. PMID 15157238 DOI: 10.1111/j.1432-0436.2004.07204003.x |
0.382 |
|
2004 |
McHardy LM, Sinotte R, Troussard A, Sheldon C, Church J, Williams DE, Andersen RJ, Dedhar S, Roberge M, Roskelley CD. The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange. Cancer Research. 64: 1468-74. PMID 14973060 DOI: 10.1158/0008-5472.Can-03-2733 |
0.308 |
|
2004 |
Ward KR, Zhang KX, Somasiri AM, Roskelley CD, Schrader JW. Expression of activated M-Ras in a murine mammary epithelial cell line induces epithelial-mesenchymal transition and tumorigenesis Oncogene. 23: 1187-1196. PMID 14961075 DOI: 10.1038/Sj.Onc.1207226 |
0.691 |
|
2004 |
Zand L, Qiang F, Roskelley CD, Leung PC, Auersperg N. Differential effects of cellular fibronectin and plasma fibronectin on ovarian cancer cell adhesion, migration, and invasion. In Vitro Cellular & Developmental Biology. Animal. 39: 178-82. PMID 14505428 DOI: 10.1007/s11626-003-0013-0 |
0.38 |
|
2003 |
Novaro V, Roskelley CD, Bissell MJ. Collagen-IV and laminin-1 regulate estrogen receptor α expression and function in mouse mammary epithelial cells Journal of Cell Science. 116: 2975-2986. PMID 12808020 DOI: 10.1242/Jcs.00523 |
0.324 |
|
2002 |
Tognon C, Knezevich SR, Huntsman D, Roskelley CD, Melnyk N, Mathers JA, Becker L, Carneiro F, MacPherson N, Horsman D, Poremba C, Sorensen PH. Expression of the ETV6-NTRK3 gene fusion as a primary event in human secretory breast carcinoma. Cancer Cell. 2: 367-76. PMID 12450792 DOI: 10.1016/S1535-6108(02)00180-0 |
0.373 |
|
2001 |
Roskelley CD, Williams DE, McHardy LM, Leong KG, Troussard A, Karsan A, Andersen RJ, Dedhar S, Roberge M. Inhibition of tumor cell invasion and angiogenesis by motuporamines. Cancer Research. 61: 6788-94. PMID 11559552 |
0.344 |
|
2001 |
Somasiri A, Howarth A, Goswami D, Dedhar S, Roskelley CD. Overexpression of the integrin-linked kinase mesenchymally transforms mammary epithelial cells. Journal of Cell Science. 114: 1125-36. PMID 11228156 |
0.358 |
|
2001 |
Somasiri A, Wu C, Ellchuk T, Turley S, Roskelley CD. Phosphatidylinositol 3-kinase is required for adherens junction-dependent mammary epithelial cell spheroid formation. Differentiation; Research in Biological Diversity. 66: 116-25. PMID 11100902 DOI: 10.1046/J.1432-0436.2000.660206.X |
0.724 |
|
2000 |
Attwell S, Roskelley C, Dedhar S. The integrin-linked kinase (ILK) suppresses anoikis. Oncogene. 19: 3811-5. PMID 10949937 DOI: 10.1038/Sj.Onc.1203711 |
0.363 |
|
2000 |
Roskelley CD, Wu C, Somasiri AM. Analysis of mammary gland morphogenesis. Methods in Molecular Biology (Clifton, N.J.). 136: 27-38. PMID 10840694 DOI: 10.1385/1-59259-065-9:27 |
0.678 |
|
2000 |
Ong A, Maines-Bandiera SL, Roskelley CD, Auersperg N. An ovarian adenocarcinoma line derived from SV40/E-cadherin-transfected normal human ovarian surface epithelium. International Journal of Cancer. 85: 430-7. PMID 10652437 DOI: 10.1002/(SICI)1097-0215(20000201)85:3<430::AID-IJC21>3.0.CO;2-Q |
0.397 |
|
1999 |
Somasiri A, Roskelley CD. Cell shape and integrin signaling regulate the differentiation state of mammary epithelial cells. Methods in Molecular Biology (Clifton, N.J.). 129: 271-83. PMID 10494571 DOI: 10.1385/1-59259-249-X:271 |
0.714 |
|
1999 |
Muschler J, Lochter A, Roskelley CD, Yurchenco P, Bissell MJ. Division of labor among the α6β4 integrin, β1 integrins, and an E3 laminin receptor to signal morphogenesis and β-casein expression in mammary epithelial cells Molecular Biology of the Cell. 10: 2817-2828. PMID 10473629 DOI: 10.1091/Mbc.10.9.2817 |
0.322 |
|
1999 |
Auersperg N, Pan J, Grove BD, Peterson T, Fisher J, Maines-Bandiera S, Somasiri A, Roskelley CD. E-cadherin induces mesenchymal-to-epithelial transition in human ovarian surface epithelium Proceedings of the National Academy of Sciences of the United States of America. 96: 6249-6254. PMID 10339573 DOI: 10.1073/Pnas.96.11.6249 |
0.719 |
|
1999 |
Wong AS, Maines-Bandiera SL, Rosen B, Wheelock MJ, Johnson KR, Leung PC, Roskelley CD, Auersperg N. Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: influence of family history of ovarian cancer. International Journal of Cancer. 81: 180-8. PMID 10188716 DOI: 10.1002/(Sici)1097-0215(19990412)81:2<180::Aid-Ijc3>3.0.Co;2-7 |
0.305 |
|
1998 |
Novak A, Hsu SC, Leung-Hagesteijn C, Radeva G, Papkoff J, Montesano R, Roskelley C, Grosschedl R, Dedhar S. Cell adhesion and the integrin-linked kinase regulate the LEF-1 and β-catenin signaling pathways Proceedings of the National Academy of Sciences of the United States of America. 95: 4374-4379. PMID 9539744 DOI: 10.1073/Pnas.95.8.4374 |
0.32 |
|
1997 |
Close MJ, Howlett AR, Roskelley CD, Desprez PY, Bailey N, Rowning B, Teng CT, Stampfer MR, Yaswen P. Lactoferrin expression in mammary epithelial cells is mediated by changes in cell shape and actin cytoskeleton. Journal of Cell Science. 110: 2861-71. PMID 9427294 |
0.398 |
|
1996 |
Roskelley CD, Bissell MJ. Dynamic reciprocity revisited: a continuous, bidirectional flow of information between cells and the extracellular matrix regulates mammary epithelial cell function. Biochemistry and Cell Biology = Biochimie Et Biologie Cellulaire. 73: 391-7. PMID 8703411 DOI: 10.1139/O95-046 |
0.314 |
|
1996 |
Roskelley CD, Auersperg N. Rapid ras-oncogene-mediated transformation maintains steroidogenic differentiation in adrenocortical parenchymal cells. Differentiation; Research in Biological Diversity. 59: 103-11. PMID 8522067 DOI: 10.1046/j.1432-0436.1995.5920103.x |
0.355 |
|
1995 |
Streuli CH, Schmidhauser C, Bailey N, Yurchenco P, Skubitz AP, Roskelley C, Bissell MJ. Laminin mediates tissue-specific gene expression in mammary epithelia. The Journal of Cell Biology. 129: 591-603. PMID 7730398 DOI: 10.1083/Jcb.129.3.591 |
0.305 |
|
1995 |
Pan J, Roskelley CD, Auersperg N. Influence of cell type on the steroidogenic potential and basal cyclic AMP levels of ras-oncogene-transformed rat cells. Differentiation; Research in Biological Diversity. 58: 321-8. PMID 7622009 DOI: 10.1046/j.1432-0436.1995.5850321.x |
0.387 |
|
1995 |
Roskelley CD, Desprez PY, Bissell MJ. Extracellular matrix-dependent tissue-specific gene expression in mammary epithelial cells requires both physical and biochemical signal transduction. Proceedings of the National Academy of Sciences of the United States of America. 91: 12378-82. PMID 7528920 DOI: 10.1073/Pnas.91.26.12378 |
0.355 |
|
1994 |
Roskelley C, Auersperg N. Mixed parenchymal-stromal populations of rat adrenocortical cells support the proliferation and differentiation of steroidogenic cells. Differentiation; Research in Biological Diversity. 55: 37-45. PMID 8299879 DOI: 10.1111/j.1432-0436.1993.tb00031.x |
0.36 |
|
1992 |
Pan J, Roskelley CD, Luu-The V, Rojiani M, Auersperg N. Reversal of divergent differentiation by ras oncogene-mediated transformation. Cancer Research. 52: 4269-72. PMID 1379124 |
0.397 |
|
1991 |
Auersperg N, Roskelley C. Retroviral oncogenes: interrelationships between neoplastic transformation and cell differentiation. Critical Reviews in Oncogenesis. 2: 125-60. PMID 1854833 |
0.314 |
|
1990 |
Roskelley CD, Auersperg N. Density separation of rat adrenocortical cells: morphology, steroidogenesis, and P-450scc expression in primary culture. In Vitro Cellular & Developmental Biology : Journal of the Tissue Culture Association. 26: 493-501. PMID 2161828 DOI: 10.1007/BF02624091 |
0.34 |
|
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