| Year |
Citation |
Score |
| 2016 |
Bridgeman BB, Wang P, Ye B, Pelling JC, Volpert OV, Tong X. Inhibition of mTOR by apigenin in UVB-irradiated keratinocytes: A new implication of skin cancer prevention. Cellular Signalling. PMID 26876613 DOI: 10.1016/J.Cellsig.2016.02.008 |
0.507 |
|
| 2014 |
Tong X, Mirzoeva S, Veliceasa D, Bridgeman BB, Fitchev P, Cornwell ML, Crawford SE, Pelling JC, Volpert OV. Chemopreventive apigenin controls UVB-induced cutaneous proliferation and angiogenesis through HuR and thrombospondin-1. Oncotarget. 5: 11413-27. PMID 25526033 DOI: 10.18632/Oncotarget.2551 |
0.409 |
|
| 2014 |
Mirzoeva S, Franzen CA, Pelling JC. Apigenin inhibits TGF-β-induced VEGF expression in human prostate carcinoma cells via a Smad2/3- and Src-dependent mechanism. Molecular Carcinogenesis. 53: 598-609. PMID 23359392 DOI: 10.1002/Mc.22005 |
0.424 |
|
| 2013 |
Tong X, Pelling JC. Targeting the PI3K/Akt/mTOR axis by apigenin for cancer prevention. Anti-Cancer Agents in Medicinal Chemistry. 13: 971-8. PMID 23272913 DOI: 10.2174/18715206113139990119 |
0.359 |
|
| 2013 |
Tong X, Bridgeman BB, Mirzoeva S, Crawford SE, Volpert OV, Pelling JC. Abstract 5075: Targeting TSP1 and inhibiting angiogenesis in UV-induced skin cancer by apigenin. Cancer Research. 73: 5075-5075. DOI: 10.1158/1538-7445.Am2013-5075 |
0.448 |
|
| 2012 |
Franzen CA, Todorović V, Desai BV, Mirzoeva S, Yang XJ, Green KJ, Pelling JC. The desmosomal armadillo protein plakoglobin regulates prostate cancer cell adhesion and motility through vitronectin-dependent Src signaling. Plos One. 7: e42132. PMID 22860065 DOI: 10.1371/Journal.Pone.0042132 |
0.467 |
|
| 2012 |
Smith KA, Tong X, Abu-Yousif AO, Mikulec CC, Gottardi CJ, Fischer SM, Pelling JC. UVB radiation-induced β-catenin signaling is enhanced by COX-2 expression in keratinocytes. Molecular Carcinogenesis. 51: 734-45. PMID 21853475 DOI: 10.1002/Mc.20840 |
0.361 |
|
| 2012 |
Tong X, Smith KA, Pelling JC. Apigenin, a chemopreventive bioflavonoid, induces AMP-activated protein kinase activation in human keratinocytes. Molecular Carcinogenesis. 51: 268-79. PMID 21538580 DOI: 10.1002/Mc.20793 |
0.493 |
|
| 2012 |
Franzen CA, Pelling JC, Bergan RC. Abstract 615: Apigenin regulates prostate cancer matrix composition and cell attachment through an integrin alpha 1 dependent pathway Cancer Research. 72: 615-615. DOI: 10.1158/1538-7445.Am2012-615 |
0.424 |
|
| 2012 |
Mirzoeva S, Franzen CA, Pelling JC. Abstract 5229: Apigenin inhibits TGF-beta-induced VEGF expression in human prostate carcinoma cells via Smad2/3 and Src/FAK/Akt signaling pathways Cancer Research. 72: 5229-5229. DOI: 10.1158/1538-7445.Am2012-5229 |
0.395 |
|
| 2012 |
Tong X, Bridgeman BB, Smith KA, Avram MJ, Pelling JC. Abstract 1587: AMPK-mTOR axis as key target for chemoprevention of UV-induced skin cancer by the bioflavonoid apigenin Cancer Research. 72: 1587-1587. DOI: 10.1158/1538-7445.Am2012-1587 |
0.504 |
|
| 2011 |
Melstrom LG, Salabat MR, Ding XZ, Strouch MJ, Grippo PJ, Mirzoeva S, Pelling JC, Bentrem DJ. Apigenin down-regulates the hypoxia response genes: HIF-1α, GLUT-1, and VEGF in human pancreatic cancer cells. Journal of Surgical Research. 167: 173-181. PMID 21227456 DOI: 10.1016/J.Jss.2010.10.041 |
0.438 |
|
| 2009 |
Franzen CA, Amargo E, Todorovi? V, Desai BV, Huda S, Mirzoeva S, Chiu K, Grzybowski BA, Chew TL, Green KJ, Pelling JC. The chemopreventive bioflavonoid apigenin inhibits prostate cancer cell motility through the focal adhesion kinase/Src signaling mechanism. Cancer Prevention Research (Philadelphia, Pa.). 2: 830-41. PMID 19737984 DOI: 10.1158/1940-6207.Capr-09-0066 |
0.454 |
|
| 2009 |
Tong X, Pelling JC. Enhancement of p53 expression in keratinocytes by the bioflavonoid apigenin is associated with RNA-binding protein HuR Molecular Carcinogenesis. 48: 118-129. PMID 18680106 DOI: 10.1002/Mc.20460 |
0.379 |
|
| 2008 |
Melstrom LG, Salabat MR, Ding XZ, Milam BM, Strouch M, Pelling JC, Bentrem DJ. Apigenin inhibits the GLUT-1 glucose transporter and the phosphoinositide 3-kinase/Akt pathway in human pancreatic cancer cells. Pancreas. 37: 426-431. PMID 18953257 DOI: 10.1097/Mpa.0B013E3181735Ccb |
0.404 |
|
| 2008 |
Abu-Yousif AO, Smith KA, Getsios S, Green KJ, Van Dross RT, Pelling JC. Enhancement of UVB-induced apoptosis by apigenin in human keratinocytes and organotypic keratinocyte cultures Cancer Research. 68: 3057-3065. PMID 18413777 DOI: 10.1158/0008-5472.Can-07-2763 |
0.398 |
|
| 2008 |
Salabat MR, Melstrom LG, Strouch MJ, Ding XZ, Milam BM, Ujiki MB, Chen C, Pelling JC, Rao S, Grippo PJ, McGarry TJ, Bentrem DJ. Geminin is overexpressed in human pancreatic cancer and downregulated by the bioflavanoid apigenin in pancreatic cancer cell lines Molecular Carcinogenesis. 47: 835-844. PMID 18404646 DOI: 10.1002/Mc.20441 |
0.481 |
|
| 2008 |
Lakshman M, Xu L, Ananthanarayanan V, Cooper J, Takimoto CH, Helenowski I, Pelling JC, Bergan RC. Dietary genistein inhibits metastasis of human prostate cancer in mice. Cancer Research. 68: 2024-32. PMID 18339885 DOI: 10.1158/0008-5472.Can-07-1246 |
0.491 |
|
| 2008 |
Mirzoeva S, Kim ND, Chiu K, Franzen CA, Bergan RC, Pelling JC. Inhibition of HIF-1 alpha and VEGF expression by the chemopreventive bioflavonoid apigenin is accompanied by Akt inhibition in human prostate carcinoma PC3-M cells. Molecular Carcinogenesis. 47: 686-700. PMID 18240292 DOI: 10.1002/Mc.20421 |
0.461 |
|
| 2007 |
Van Dross RT, Hong X, Essengue S, Fischer SM, Pelling JC. Modulation of UVB-induced and basal cyclooxygenase-2 (COX-2) expression by apigenin in mouse keratinocytes: Role of USF transcription factors Molecular Carcinogenesis. 46: 303-314. PMID 17186551 DOI: 10.1002/Mc.20281 |
0.442 |
|
| 2007 |
Tong X, Dross RTV, Abu-Yousif A, Morrison AR, Pelling JC. Apigenin Prevents UVB-Induced Cyclooxygenase 2 Expression: Coupled mRNA Stabilization and Translational Inhibition Molecular and Cellular Biology. 27: 283-296. PMID 17074806 DOI: 10.1128/Mcb.01282-06 |
0.449 |
|
| 2007 |
McGill JJ, Golkar L, Salabat MR, Ujiki MB, Milam B, Hieferman DM, Pelling JC, Talamonti MS, Bentrem DJ. P89: Antitumor effects of apigenin alone and in combination with gemcitabine via PI3/Akt pathway inhibition in pancreatic cancer cells Journal of Surgical Research. 137: 2-3. DOI: 10.1016/J.Jss.2006.12.318 |
0.474 |
|
| 2007 |
Golkar L, Salabat MR, Ujiki MB, Ding X, Milam B, Chen C, Heiferman DM, Pelling JC, Talamonti MS, Bentrem DJ. 97: Apigenin inhibits pancreatic cancer cell proliferation via down-regulation of hypoxia inducible factor-1Α (HIF-1Α) and the glucose transporter (GLUT-1) Journal of Surgical Research. 137: 191-192. DOI: 10.1016/J.Jss.2006.12.108 |
0.359 |
|
| 2006 |
Dross RV, Browning PJ, Pelling JC. Do truncated cyclins contribute to aberrant cyclin expression in cancer Cell Cycle. 5: 472-477. PMID 16552186 DOI: 10.4161/Cc.5.5.2516 |
0.428 |
|
| 2006 |
Salabat MR, Golkar L, Ding XZ, Chen C, Ujiki MB, Rao S, Pelling JC, McGill JJ, Strouch M, Heiferman DM, Bell RH, Talamonti MS, Bentrem DJ. Geminin, A Replication Inhibitor Protein, Is Over-Expressed In Pancreatic Cancer Tissue And Apigenin Affects Replication By Down-Regulating Geminin And Cdc6, But Not Cdt-1 In Pancreatic Cancer Cells Pancreas. 33: 494. DOI: 10.1097/00006676-200611000-00195 |
0.422 |
|
| 2006 |
Golkar L, Salabat MR, Ding XZ, Ujiki MB, Rao S, McGill JJ, Chen C, Heiferman DM, Pelling J, Bell RH, Talamonti MS, Bentrem DJ. Apigenin Inhibits Pancreatic Cancer Cell Proliferation Via Down-Regulation Of The Glut-1 Glucose Transporter Through The Phosphoinositide 3-Kinase (Pi3K)/Akt Signaling Pathway Pancreas. 33: 464. DOI: 10.1097/00006676-200611000-00094 |
0.442 |
|
| 2006 |
Salabat MR, Golkar L, Ding X, Ujiki MB, Pelling JC, Bell RH, Adrian TE, Talamonti MS, Bentrem DJ. Apigenin causes growth arrest in pancreatic cancer cells through down-regulation of the replication inhibitor protein, Geminin via both transcription and ubiquitin-mediated degradation Journal of the American College of Surgeons. 203. DOI: 10.1016/J.Jamcollsurg.2006.05.223 |
0.451 |
|
| 2005 |
Dross RTV, Hong X, Pelling JC. Inhibition of TPA-induced cyclooxygenase-2 (COX-2) expression by apigenin through downregulation of Akt signal transduction in human keratinocytes Molecular Carcinogenesis. 44: 83-91. PMID 16044407 DOI: 10.1002/Mc.20123 |
0.515 |
|
| 2003 |
Dross RV, Xue Y, Knudson A, Pelling JC. The Chemopreventive Bioflavonoid Apigenin Modulates Signal Transduction Pathways in Keratinocyte and Colon Carcinoma Cell Lines Journal of Nutrition. 133. PMID 14608117 DOI: 10.1093/Jn/133.11.3800S |
0.441 |
|
| 2003 |
Yamaguchi T, Nagao S, Wallace DP, Belibi FA, Cowley BD, Pelling JC, Grantham JJ. Cyclic AMP activates B-Raf and ERK in cyst epithelial cells from autosomal-dominant polycystic kidneys Kidney International. 63: 1983-1994. PMID 12753285 DOI: 10.1046/J.1523-1755.2003.00023.X |
0.448 |
|
| 2003 |
Liao X, Thrasher JB, Pelling J, Holzbeierlein J, Sang QA, Li B. Androgen stimulates matrix metalloproteinase-2 expression in human prostate cancer Endocrinology. 144: 1656-1663. PMID 12697668 DOI: 10.1210/En.2002-0157 |
0.367 |
|
| 2003 |
Xue Y, Ramaswamy NT, Hong X, Pelling JC. Association of JNK1 with p21waf1 and p53: modulation of JNK1 activity. Molecular Carcinogenesis. 36: 38-44. PMID 12503078 DOI: 10.1002/Mc.10096 |
0.444 |
|
| 2002 |
McVean M, Weinberg WC, Pelling JC. A p21waf1-independent pathway for inhibitory phosphorylation of cyclin-dependent kinase p34cdc2 and concomitant G2/m arrest by the chemopreventive flavonoid apigenin Molecular Carcinogenesis. 33: 36-43. PMID 11807956 DOI: 10.1002/Mc.10016 |
0.412 |
|
| 2001 |
Mahadevan B, Luch A, Seidel A, Pelling JC, Baird WM. Effects of the (-)-anti-11R,12S-dihydrodiol 13S,14R-epoxide of dibenzo. Carcinogenesis. 22: 161-9. PMID 11159755 DOI: 10.1093/Carcin/22.1.161 |
0.359 |
|
| 2000 |
Cui W, Yazlovitskaya EM, Mayo MS, Pelling JC, Persons DL. Cisplatin-induced response of c-jun N-terminal kinase 1 and extracellular signal--regulated protein kinases 1 and 2 in a series of cisplatin-resistant ovarian carcinoma cell lines. Molecular Carcinogenesis. 29: 219-228. PMID 11170260 DOI: 10.1002/1098-2744(200012)29:4<219::Aid-Mc1004>3.0.Co;2-D |
0.442 |
|
| 2000 |
Persons DL, Yazlovitskaya EM, Pelling JC. Effect of Extracellular Signal-regulated Kinase on p53 Accumulation in Response to Cisplatin Journal of Biological Chemistry. 275: 35778-35785. PMID 10958792 DOI: 10.1074/Jbc.M004267200 |
0.452 |
|
| 2000 |
Wang W, Heideman L, Chung CS, Pelling JC, Koehler KJ, Birt DF. Cell-cycle arrest at G2/M and growth inhibition by apigenin in human colon carcinoma cell lines. Molecular Carcinogenesis. 28: 102-10. PMID 10900467 DOI: 10.1002/1098-2744(200006)28:2<102::Aid-Mc6>3.0.Co;2-2 |
0.444 |
|
| 2000 |
Yamaguchi T, Pelling JC, Ramaswamy NT, Eppler JW, Wallace DP, Nagao S, Rome LA, Sullivan LP, Grantham JJ. cAMP stimulates the in vitro proliferation of renal cyst epithelial cells by activating the extracellular signal-regulated kinase pathway. Kidney International. 57: 1460-71. PMID 10760082 DOI: 10.1046/J.1523-1755.2000.00991.X |
0.443 |
|
| 2000 |
McVean M, Xiao H, Isobe K, Pelling JC. Increase in wild-type p53 stability and transactivational activity by the chemopreventive agent apigenin in keratinocytes. Carcinogenesis. 21: 633-639. PMID 10753197 DOI: 10.1093/Carcin/21.4.633 |
0.399 |
|
| 1999 |
Ramaswamy NT, Pelling JC. Mutational status of the p53 gene modulates the basal level of jun N-terminal kinase and its inducibility by ultraviolet irradiation in A1-5 rat fibroblasts. Molecular Carcinogenesis. 25: 262-72. PMID 10449033 DOI: 10.1002/(Sici)1098-2744(199908)25:4<262::Aid-Mc5>3.0.Co;2-U |
0.468 |
|
| 1999 |
Yazlovitskaya EM, Pelling JC, Persons DL. Association of apoptosis with the inhibition of extracellular signal–regulated protein kinase activity in the tumor necrosis factor α‐resistant ovarian carcinoma cell line UCI 101 Molecular Carcinogenesis. 25: 14-20. PMID 10331740 DOI: 10.1002/(Sici)1098-2744(199905)25:1<14::Aid-Mc2>3.0.Co;2-V |
0.381 |
|
| 1998 |
Neades R, Cox L, Pelling JC. S-phase arrest in mouse keratinocytes exposed to multiple doses of ultraviolet B/A radiation. Molecular Carcinogenesis. 23: 159-167. PMID 9833776 DOI: 10.1002/(Sici)1098-2744(199811)23:3<159::Aid-Mc4>3.0.Co;2-J |
0.379 |
|
| 1998 |
Ramaswamy NT, Ronai Z, Pelling JC. Rapid activation of JNK1 in UV-B irradiated epidermal keratinocytes. Oncogene. 16: 1501-5. PMID 9525748 DOI: 10.1038/Sj.Onc.1201628 |
0.405 |
|
| 1997 |
Lepley DM, Pelling JC. Induction of p21/WAF1 and G1 cell-cycle arrest by the chemopreventive agent apigenin. Molecular Carcinogenesis. 19: 74-82. PMID 9210954 DOI: 10.1002/(Sici)1098-2744(199707)19:2<74::Aid-Mc2>3.0.Co;2-L |
0.443 |
|
| 1997 |
Lepley DM, Li B, Birt DF, Pelling JC. The chemopreventive flavonoid apigenin induces G2/M arrest in keratinocytes. Carcinogenesis. 17: 2367-75. PMID 8968050 DOI: 10.1093/Carcin/17.11.2367 |
0.473 |
|
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