Raymond A. Pederson - Publications

Affiliations: 
University of British Columbia, Vancouver, Vancouver, BC, Canada 
Area:
Animal Physiology Biology, Molecular Biology, Pathology

107 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2016 Pederson RA, McIntosh CH. Discovery of gastric inhibitory polypeptide and its subsequent fate: Personal reflections. Journal of Diabetes Investigation. 7: 4-7. PMID 27186348 DOI: 10.1111/Jdi.12480  0.538
2011 Brown JC, Buchan AMJ, McIntosh CHS, Pederson RA. Gastric Inhibitory Polypeptide Comprehensive Physiology. DOI: 10.1002/Cphy.Cp060218  0.386
2009 Gelling RW, Vuguin PM, Du XQ, Cui L, Rømer J, Pederson RA, Leiser M, Sørensen H, Holst JJ, Fledelius C, Johansen PB, Fleischer N, McIntosh CH, Nishimura E, Charron MJ. Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass. American Journal of Physiology. Endocrinology and Metabolism. 297: E695-707. PMID 19602585 DOI: 10.1152/Ajpendo.00082.2009  0.557
2007 Piteau S, Olver A, Kim SJ, Winter K, Pospisilik JA, Lynn F, Manhart S, Demuth HU, Speck M, Pederson RA, McIntosh CH. Reversal of islet GIP receptor down-regulation and resistance to GIP by reducing hyperglycemia in the Zucker rat. Biochemical and Biophysical Research Communications. 362: 1007-12. PMID 17803965 DOI: 10.1016/J.Bbrc.2007.08.115  0.78
2007 Winter KD, Ehses JA, Eeson G, Kim S, Nian C, Warnock G, Pederson RA, McIntosh CH. EFFECTS OF GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE ON THE PHOSPHORYLATION OF PROTEIN KINASE B (PKB/AKT) AND ITS CONTRIBUTION TO PANCREATIC BETA-CELL SURVIVAL. Journal of Investigative Medicine. 55: S76. DOI: 10.1097/00042871-200701010-00011  0.48
2006 Hinke SA, Pederson RA, McIntosh CH. Relative contribution of incretins to the glucose lowering effect of DP IV inhibitors in type 2 diabetes mellitus (T2DM). Advances in Experimental Medicine and Biology. 575: 119-33. PMID 16700515 DOI: 10.1007/0-387-32824-6_13  0.435
2006 McIntosh CH, Demuth HU, Kim SJ, Pospisilik JA, Pederson RA. Applications of dipeptidyl peptidase IV inhibitors in diabetes mellitus. The International Journal of Biochemistry & Cell Biology. 38: 860-72. PMID 16442340 DOI: 10.1016/J.Biocel.2005.12.013  0.756
2005 Demuth HU, McIntosh CH, Pederson RA. Type 2 diabetes--therapy with dipeptidyl peptidase IV inhibitors. Biochimica Et Biophysica Acta. 1751: 33-44. PMID 15978877 DOI: 10.1016/J.Bbapap.2005.05.010  0.479
2005 McIntosh CH, Demuth HU, Pospisilik JA, Pederson R. Dipeptidyl peptidase IV inhibitors: how do they work as new antidiabetic agents? Regulatory Peptides. 128: 159-65. PMID 15780435 DOI: 10.1016/J.Regpep.2004.06.001  0.711
2004 Hinke SA, Manhart S, Speck M, Pederson RA, Demuth HU, McIntosh CH. In depth analysis of the N-terminal bioactive domain of gastric inhibitory polypeptide. Life Sciences. 75: 1857-70. PMID 15302229 DOI: 10.1016/J.Lfs.2004.03.024  0.447
2004 Hinke SA, Manhart S, Kühn-Wache K, Nian C, Demuth HU, Pederson RA, McIntosh CH. [Ser2]- and [SerP2] incretin analogs: comparison of dipeptidyl peptidase IV resistance and biological activities in vitro and in vivo. The Journal of Biological Chemistry. 279: 3998-4006. PMID 14610075 DOI: 10.1074/Jbc.M311304200  0.519
2003 Ehses JA, Casilla VR, Doty T, Pospisilik JA, Winter KD, Demuth HU, Pederson RA, McIntosh CH. Glucose-dependent insulinotropic polypeptide promotes beta-(INS-1) cell survival via cyclic adenosine monophosphate-mediated caspase-3 inhibition and regulation of p38 mitogen-activated protein kinase. Endocrinology. 144: 4433-45. PMID 12960055 DOI: 10.1210/En.2002-0068  0.723
2003 Hinke SA, Gelling R, Manhart S, Lynn F, Pederson RA, Kühn-Wache K, Rosche F, Demuth HU, Coy D, McIntosh CH. Structure-activity relationships of glucose-dependent insulinotropic polypeptide (GIP). Biological Chemistry. 384: 403-7. PMID 12715891 DOI: 10.1515/Bc.2003.046  0.656
2003 Hinke SA, Lynn F, Ehses J, Pamir N, Manhart S, Kühn-Wache K, Rosche F, Demuth HU, Pederson RA, McIntosh CH. Glucose-dependent insulinotropic polypeptide (GIP): development of DP IV-resistant analogues with therapeutic potential. Advances in Experimental Medicine and Biology. 524: 293-301. PMID 12675251 DOI: 10.1007/0-306-47920-6_35  0.697
2003 Pospisilik JA, Ehses JA, Doty T, McIntosh CH, Demuth HU, Pederson RA. Dipeptidyl peptidase IV inhibition in animal models of diabetes. Advances in Experimental Medicine and Biology. 524: 281-91. PMID 12675250 DOI: 10.1007/0-306-47920-6_34  0.72
2003 Manhart S, Hinke SA, McIntosh CH, Pederson RA, Demuth HU. Structure-function analysis of a series of novel GIP analogues containing different helical length linkers. Biochemistry. 42: 3081-8. PMID 12627975 DOI: 10.1021/Bi026868E  0.394
2003 Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Ehlers MR, Egan JM, Elahi D. Effect of glucagon-like peptide 1 (7-36 amide) on insulin-mediated glucose uptake in patients with type 1 diabetes. Diabetes Care. 26: 837-42. PMID 12610046 DOI: 10.2337/Diacare.26.3.837  0.525
2003 Pospisilik JA, Martin J, Doty T, Ehses JA, Pamir N, Lynn FC, Piteau S, Demuth HU, McIntosh CH, Pederson RA. Dipeptidyl peptidase IV inhibitor treatment stimulates beta-cell survival and islet neogenesis in streptozotocin-induced diabetic rats. Diabetes. 52: 741-50. PMID 12606516 DOI: 10.2337/Diabetes.52.3.741  0.811
2003 Pamir N, Lynn FC, Buchan AM, Ehses J, Hinke SA, Pospisilik JA, Miyawaki K, Yamada Y, Seino Y, McIntosh CH, Pederson RA. Glucose-dependent insulinotropic polypeptide receptor null mice exhibit compensatory changes in the enteroinsular axis. American Journal of Physiology. Endocrinology and Metabolism. 284: E931-9. PMID 12540373 DOI: 10.1152/Ajpendo.00270.2002  0.793
2003 Wasan KM, Zamfir C, Pritchard PH, Pederson RA. Influence of phytostanol phosphoryl ascorbate (FM-VP4) on insulin resistance, hyperglycemia, plasma lipid levels, and gastrointestinal absorption of exogenous cholesterol in Zucker (fa/fa) fatty and lean rats. Journal of Pharmaceutical Sciences. 92: 281-8. PMID 12532378 DOI: 10.1002/Jps.10297  0.529
2003 Lynn FC, Thompson SA, Pospisilik JA, Ehses JA, Hinke SA, Pamir N, McIntosh CH, Pederson RA. A novel pathway for regulation of glucose-dependent insulinotropic polypeptide (GIP) receptor expression in beta cells. Faseb Journal : Official Publication of the Federation of American Societies For Experimental Biology. 17: 91-3. PMID 12475913 DOI: 10.1096/Fj.02-0243Fje  0.811
2002 Pospisilik JA, Stafford SG, Demuth HU, McIntosh CH, Pederson RA. Long-term treatment with dipeptidyl peptidase IV inhibitor improves hepatic and peripheral insulin sensitivity in the VDF Zucker rat: a euglycemic-hyperinsulinemic clamp study. Diabetes. 51: 2677-83. PMID 12196458 DOI: 10.2337/Diabetes.51.9.2677  0.776
2002 Hinke SA, McIntosh CH, Hoffmann T, Kühn-Wache K, Wagner L, Bär J, Manhart S, Wermann M, Pederson RA, Demuth HU. On combination therapy of diabetes with metformin and dipeptidyl peptidase IV inhibitors. Diabetes Care. 25: 1490-1; author reply. PMID 12145269 DOI: 10.2337/Diacare.25.8.1490-B  0.467
2002 Ehses JA, Pelech SL, Pederson RA, McIntosh CH. Glucose-dependent insulinotropic polypeptide activates the Raf-Mek1/2-ERK1/2 module via a cyclic AMP/cAMP-dependent protein kinase/Rap1-mediated pathway. The Journal of Biological Chemistry. 277: 37088-97. PMID 12138104 DOI: 10.1074/Jbc.M205055200  0.424
2002 Pospisilik JA, Stafford SG, Demuth HU, Brownsey R, Parkhouse W, Finegood DT, McIntosh CH, Pederson RA. Long-term treatment with the dipeptidyl peptidase IV inhibitor P32/98 causes sustained improvements in glucose tolerance, insulin sensitivity, hyperinsulinemia, and beta-cell glucose responsiveness in VDF (fa/fa) Zucker rats. Diabetes. 51: 943-50. PMID 11916911 DOI: 10.2337/Diabetes.51.4.943  0.777
2002 Hinke SA, Kühn-Wache K, Hoffmann T, Pederson RA, McIntosh CH, Demuth HU. Metformin effects on dipeptidylpeptidase IV degradation of glucagon-like peptide-1. Biochemical and Biophysical Research Communications. 291: 1302-8. PMID 11883961 DOI: 10.1006/Bbrc.2002.6607  0.399
2002 Hinke SA, Gelling RW, Pederson RA, Manhart S, Nian C, Demuth HU, McIntosh CH. Dipeptidyl peptidase IV-resistant [D-Ala(2)]glucose-dependent insulinotropic polypeptide (GIP) improves glucose tolerance in normal and obese diabetic rats. Diabetes. 51: 652-61. PMID 11872663 DOI: 10.2337/Diabetes.51.3.652  0.563
2001 Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Gingerich R, Egan JM, Elahi D. Glucagon-like peptide-1 (7-37) augments insulin-mediated glucose uptake in elderly patients with diabetes. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 56: M681-5. PMID 11682575 DOI: 10.1093/Gerona/56.11.M681  0.558
2001 Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Gingerich R, Egan JM, Finegood DT, Elahi D. Effect of glucagon-like peptide 1 on non-insulin-mediated glucose uptake in the elderly patient with diabetes. Diabetes Care. 24: 1951-6. PMID 11679463 DOI: 10.2337/Diacare.24.11.1951  0.57
2001 Korosi J, McIntosh CH, Pederson RA, Demuth HU, Habener JF, Gingerich R, Egan JM, Elahi D, Meneilly GS. Effect of aging and diabetes on the enteroinsular axis. The Journals of Gerontology. Series a, Biological Sciences and Medical Sciences. 56: M575-9. PMID 11524451 DOI: 10.1093/Gerona/56.9.M575  0.33
2001 Meneilly GS, McIntosh CH, Pederson RA, Habener JF, Gingerich R, Egan JM, Elahi D. Glucagon-like peptide-1 (7-37) augments insulin release in elderly patients with diabetes. Diabetes Care. 24: 964-5. PMID 11347771 DOI: 10.2337/Diacare.24.5.964  0.495
2001 Hinke SA, Manhart S, Pamir N, Demuth H, W Gelling R, Pederson RA, McIntosh CH. Identification of a bioactive domain in the amino-terminus of glucose-dependent insulinotropic polypeptide (GIP). Biochimica Et Biophysica Acta. 1547: 143-55. PMID 11343800 DOI: 10.1016/S0167-4838(01)00181-9  0.599
2001 Lynn FC, Pamir N, Ng EH, McIntosh CH, Kieffer TJ, Pederson RA. Defective glucose-dependent insulinotropic polypeptide receptor expression in diabetic fatty Zucker rats. Diabetes. 50: 1004-11. PMID 11334402 DOI: 10.2337/Diabetes.50.5.1004  0.77
2001 Ehses JA, Lee SS, Pederson RA, McIntosh CH. A new pathway for glucose-dependent insulinotropic polypeptide (GIP) receptor signaling: evidence for the involvement of phospholipase A2 in GIP-stimulated insulin secretion. The Journal of Biological Chemistry. 276: 23667-73. PMID 11323439 DOI: 10.1074/Jbc.M103023200  0.512
2001 Pospisilik JA, Hinke SA, Pederson RA, Hoffmann T, Rosche F, Schlenzig D, Glund K, Heiser U, McIntosh CH, Demuth H. Metabolism of glucagon by dipeptidyl peptidase IV (CD26). Regulatory Peptides. 96: 133-41. PMID 11111019 DOI: 10.1016/S0167-0115(00)00170-1  0.695
2000 Meneilly GS, Demuth HU, McIntosh CH, Pederson RA. Effect of ageing and diabetes on glucose-dependent insulinotropic polypeptide and dipeptidyl peptidase IV responses to oral glucose. Diabetic Medicine : a Journal of the British Diabetic Association. 17: 346-50. PMID 10872532 DOI: 10.1046/J.1464-5491.2000.00236.X  0.546
2000 Kühn-Wache K, Manhart S, Hoffmann T, Hinke SA, Gelling R, Pederson RA, McIntosh CH, Demuth HU. Analogs of glucose-dependent insulinotropic polypeptide with increased dipeptidyl peptidase IV resistance. Advances in Experimental Medicine and Biology. 477: 187-95. PMID 10849746 DOI: 10.1007/0-306-46826-3_21  0.389
2000 Hinke SA, Pauly RP, Ehses J, Kerridge P, Demuth HU, McIntosh CH, Pederson RA. Role of glucose in chronic desensitization of isolated rat islets and mouse insulinoma (betaTC-3) cells to glucose-dependent insulinotropic polypeptide. The Journal of Endocrinology. 165: 281-91. PMID 10810292 DOI: 10.1677/Joe.0.1650281  0.574
2000 Hinke SA, Pospisilik JA, Demuth HU, Mannhart S, Kühn-Wache K, Hoffmann T, Nishimura E, Pederson RA, McIntosh CH. Dipeptidyl peptidase IV (DPIV/CD26) degradation of glucagon. Characterization of glucagon degradation products and DPIV-resistant analogs. The Journal of Biological Chemistry. 275: 3827-34. PMID 10660533 DOI: 10.1074/Jbc.275.6.3827  0.687
2000 Demuth H, Hoffmann T, Glund K, McIntosh CH, Pederson RA, Fuecker K, Fischer S, Hanefeld M. Single dose treatment of type 2 diabetics by the DP IV-inhibitor P32/98 Diabetes Research and Clinical Practice. 50: 386. DOI: 10.1016/S0168-8227(00)81317-0  0.304
2000 Demuth H, Hoffmann T, Freyse E, Berg S, Heinke P, McIntosh CH, Pederson RA. Prodrugs of DP IV-inhibitors strongly improve incretin-mediated glucose tolerance Diabetes Research and Clinical Practice. 50: 386. DOI: 10.1016/S0168-8227(00)81316-9  0.475
2000 Demuth H, Hoffmann T, Glund K, Freyse E, Berg S, Heinke P, McIntosh CH, Pederson RA. Prodrugs of DP IV-inhibitors strongly improve incretin-mediated glucose tolerance Regulatory Peptides. 94: 59. DOI: 10.1016/S0167-0115(00)80118-4  0.375
2000 Demuth H, Glund K, Banke-Bochita J, Rost K, Fischer S, Hanefeld M, McIntosh CH, Pederson RA. Dipeptidyl peptidase IV (DP IV)-modulations as treatment of impaired glucose tolerance and niddm Regulatory Peptides. 94: 16. DOI: 10.1016/S0167-0115(00)80032-4  0.436
1999 McIntosh CH, Bremsak I, Lynn FC, Gill R, Hinke SA, Gelling R, Nian C, McKnight G, Jaspers S, Pederson RA. Glucose-Dependent Insulinotropic Polypeptide Stimulation of Lipolysis in Differentiated 3T3-L1 Cells: Wortmannin-Sensitive Inhibition by Insulin* * This work was supported by grants from Zymogenetics Inc. (Seattle, WA), the Medical Research Council of Canada (5-90007-RAP/CHSM) and the Canadian Diabetes Association (CHSM/RAP). Endocrinology. 140: 398-404. PMID 28200744 DOI: 10.1210/endo.140.1.6464  0.7
1999 Wheeler MB, Gelling RW, Hinke SA, Tu B, Pederson RA, Lynn F, Ehses J, McIntosh CH. Characterization of the carboxyl-terminal domain of the rat glucose-dependent insulinotropic polypeptide (GIP) receptor. A role for serines 426 and 427 in regulating the rate of internalization. The Journal of Biological Chemistry. 274: 24593-601. PMID 10455124 DOI: 10.1074/Jbc.274.35.24593  0.692
1999 Pauly RP, Demuth HU, Rosche F, Schmidt J, White HA, Lynn F, McIntosh CH, Pederson RA. Improved glucose tolerance in rats treated with the dipeptidyl peptidase IV (CD26) inhibitor Ile-thiazolidide. Metabolism: Clinical and Experimental. 48: 385-9. PMID 10094118 DOI: 10.1016/S0026-0495(99)90090-2  0.767
1999 McIntosh CH, Bremsak I, Lynn FC, Gill R, Hinke SA, Gelling R, Nian C, McKnight G, Jaspers S, Pederson RA. Glucose-dependent insulinotropic polypeptide stimulation of lipolysis in differentiated 3T3-L1 cells: wortmannin-sensitive inhibition by insulin. Endocrinology. 140: 398-404. PMID 9886851 DOI: 10.1210/Endo.140.1.6464  0.741
1998 Pederson RA, White HA, Schlenzig D, Pauly RP, McIntosh CH, Demuth HU. Improved glucose tolerance in Zucker fatty rats by oral administration of the dipeptidyl peptidase IV inhibitor isoleucine thiazolidide. Diabetes. 47: 1253-8. PMID 9703325 DOI: 10.2337/Diab.47.8.1253  0.554
1998 Pederson RA, Satkunarajah M, McIntosh CH, Scrocchi LA, Flamez D, Schuit F, Drucker DJ, Wheeler MB. Enhanced glucose-dependent insulinotropic polypeptide secretion and insulinotropic action in glucagon-like peptide 1 receptor -/- mice. Diabetes. 47: 1046-52. PMID 9648827 DOI: 10.2337/Diabetes.47.7.1046  0.526
1997 Gelling RW, Coy DH, Pederson RA, Wheeler MB, Hinke S, Kwan T, McIntosh CH. GIP(6-30amide) contains the high affinity binding region of GIP and is a potent inhibitor of GIP1-42 action in vitro. Regulatory Peptides. 69: 151-4. PMID 9226399 DOI: 10.1016/S0167-0115(97)00009-8  0.423
1997 Irwin DM, Satkunarajah M, Wen Y, Brubaker PL, Pederson RA, Wheeler MB. The Xenopus proglucagon gene encodes novel GLP-1-like peptides with insulinotropic properties. Proceedings of the National Academy of Sciences of the United States of America. 94: 7915-20. PMID 9223287 DOI: 10.1073/Pnas.94.15.7915  0.479
1997 Gelling RW, Wheeler MB, Xue J, Gyomorey S, Nian C, Pederson RA, McIntosh CH. Localization of the domains involved in ligand binding and activation of the glucose-dependent insulinotropic polypeptide receptor. Endocrinology. 138: 2640-3. PMID 9165060 DOI: 10.1210/Endo.138.6.9104  0.324
1996 Morrow GW, Kieffer TJ, McIntosh CH, MacGillivray RT, Brown JC, St Pierre S, Pederson RA. The insulinotropic region of gastric inhibitory polypeptide; fragment analysis suggests the bioactive site lies between residues 19 and 30. Canadian Journal of Physiology and Pharmacology. 74: 65-72. PMID 8963953 DOI: 10.1139/Y95-229  0.46
1996 Yuen VG, Pederson RA, Dai S, Orvig C, McNeill JH. Effects of low and high dose administration of bis(maltolato)oxovanadium(IV) on fa/fa Zucker rats. Canadian Journal of Physiology and Pharmacology. 74: 1001-9. PMID 8960391 DOI: 10.1139/Y96-102  0.509
1996 Pederson RA, Kieffer TJ, Pauly R, Kofod H, Kwong J, McIntosh CH. The enteroinsular axis in dipeptidyl peptidase IV-negative rats. Metabolism: Clinical and Experimental. 45: 1335-41. PMID 8931636 DOI: 10.1016/S0026-0495(96)90112-2  0.555
1996 Pauly RP, Rosche F, Wermann M, McIntosh CH, Pederson RA, Demuth HU. Investigation of glucose-dependent insulinotropic polypeptide-(1-42) and glucagon-like peptide-1-(7-36) degradation in vitro by dipeptidyl peptidase IV using matrix-assisted laser desorption/ionization-time of flight mass spectrometry. A novel kinetic approach. The Journal of Biological Chemistry. 271: 23222-9. PMID 8798518 DOI: 10.1074/Jbc.271.38.23222  0.46
1996 Schieldrop PJ, Gelling RW, Elliot R, Hewitt J, Kieffer TJ, McIntosh CH, Pederson RA. Isolation of a murine glucose-dependent insulinotropic polypeptide (GIP) cDNA from a tumor cell line (STC6-14) and quantification of glucose-induced increases in GIP mRNA. Biochimica Et Biophysica Acta. 1308: 111-3. PMID 8764827 DOI: 10.1016/0167-4781(96)00103-0  0.456
1996 Gelling RW, Yan W, Su R-, Mathi SK, Gyomorey S, Pederson RA, McIntosh CHS, Wheeler MB. The car☐y-terminal tail length of the rat islet glucose-dependent insulinotropic polypeptide is important for efficient expression at the membrane level, and activation of adenylyl cyclase Regulatory Peptides. 64: 51. DOI: 10.1016/0167-0115(96)87822-0  0.447
1995 Jones PJ, Namchuk GL, Pederson RA. Meal frequency influences circulating hormone levels but not lipogenesis rates in humans. Metabolism: Clinical and Experimental. 44: 218-23. PMID 7869919 DOI: 10.1016/0026-0495(95)90268-6  0.334
1995 Jia X, Brown JC, Ma P, Pederson RA, McIntosh CH. Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion. The American Journal of Physiology. 268: E645-51. PMID 7733263 DOI: 10.1152/Ajpendo.1995.268.4.E645  0.579
1995 Jia X, Elliott R, Kwok YN, Pederson RA, McIntosh CH. Altered glucose dependence of glucagon-like peptide I(7-36)-induced insulin secretion from the Zucker (fa/fa) rat pancreas. Diabetes. 44: 495-500. PMID 7729605 DOI: 10.2337/Diab.44.5.495  0.56
1995 Wheeler MB, Gelling RW, McIntosh CH, Georgiou J, Brown JC, Pederson RA. Functional expression of the rat pancreatic islet glucose-dependent insulinotropic polypeptide receptor: ligand binding and intracellular signaling properties. Endocrinology. 136: 4629-39. PMID 7664683 DOI: 10.1210/Endo.136.10.7664683  0.391
1995 Kieffer TJ, Huang Z, McIntosh CH, Buchan AM, Brown JC, Pederson RA. Gastric inhibitory polypeptide release from a tumor-derived cell line. The American Journal of Physiology. 269: E316-22. PMID 7653549 DOI: 10.1152/Ajpendo.1995.269.2.E316  0.441
1995 Kieffer TJ, McIntosh CH, Pederson RA. Degradation of glucose-dependent insulinotropic polypeptide and truncated glucagon-like peptide 1 in vitro and in vivo by dipeptidyl peptidase IV. Endocrinology. 136: 3585-96. PMID 7628397 DOI: 10.1210/Endo.136.8.7628397  0.512
1994 Bryer-Ash M, Cheung A, Pederson RA. Feedback regulation of glucose-dependent insulinotropic polypeptide (GIP) secretion by insulin in conscious rats Regulatory Peptides. 51: 101-109. PMID 8059006 DOI: 10.1016/0167-0115(94)90199-6  0.453
1994 Kieffer TJ, Buchan AM, Barker H, Brown JC, Pederson RA. Release of gastric inhibitory polypeptide from cultured canine endocrine cells. The American Journal of Physiology. 267: E489-96. PMID 7943296 DOI: 10.1152/Ajpendo.1994.267.4.E489  0.434
1994 Jia X, Brown JC, Kwok YN, Pederson RA, McIntosh CH. Gastric inhibitory polypeptide and glucagon-like peptide-1(7-36) amide exert similar effects on somatostatin secretion but opposite effects on gastrin secretion from the rat stomach. Canadian Journal of Physiology and Pharmacology. 72: 1215-9. PMID 7882187 DOI: 10.1139/Y94-172  0.461
1993 Jones PJ, Leitch CA, Pederson RA. Meal-frequency effects on plasma hormone concentrations and cholesterol synthesis in humans. The American Journal of Clinical Nutrition. 57: 868-74. PMID 8503355 DOI: 10.1093/Ajcn/57.6.868  0.363
1992 Väänänen JE, Buchan AM, Pederson RA. A rapid, sensitive, and easy-to-perform solid phase insulin radioimmunoassay. Life Sciences. 50: PL143-8. PMID 1569827 DOI: 10.1016/0024-3205(92)90330-R  0.505
1992 Curtis SB, Buchan AM, Pederson RA, Brown JC. Insulin response of cultured islets from diabetic and nondiabetic BB rats. Metabolism: Clinical and Experimental. 41: 1047-52. PMID 1357529 DOI: 10.1016/0026-0495(92)90284-H  0.57
1991 Pederson RA, Curtis SB, Chisholm CB, Gaba NR, Campos RV, Brown JC. Insulin secretion and islet endocrine cell content at onset and during the early stages of diabetes in the BB rat: effect of the level of glycemic control. Canadian Journal of Physiology and Pharmacology. 69: 1230-6. PMID 1782606 DOI: 10.1139/Y91-180  0.574
1990 Pederson RA, Ramanadham S, Buchan AM, McNeill JH. Long-term effects of vanadyl treatment on streptozocin-induced diabetes in rats. Diabetes. 38: 1390-5. PMID 2695373 DOI: 10.2337/Diab.38.11.1390  0.571
1990 Chow BK, Morrow GW, Ho M, Pederson RA, McIntosh CH, Brown JC, MacGillivray RT. Expression of recombinant human glucose-dependent insulinotropic polypeptide in Escherichia coli by sequence-specific proteolysis of a protein A fusion protein. Peptides. 11: 1069-74. PMID 2087431 DOI: 10.1016/0196-9781(90)90132-O  0.411
1990 Campos RV, Buchan AM, Meloche RM, Pederson RA, Kwok YN, Coy DH. Gastrin secretion from human antral G cells in culture. Gastroenterology. 99: 36-44. PMID 1971610 DOI: 10.1016/0016-5085(90)91226-V  0.388
1989 Pederson RA, Campos RV, Chan CB, Buchan AMJ, Wheeler MB, Brown JC. Gastrin release in obese Zucker rats Regulatory Peptides. 24: 131-141. PMID 2564209 DOI: 10.1016/0167-0115(89)90232-2  0.318
1989 Campos RV, Buchan AM, Pederson RA, McIntosh CH, Coy DH. Inhibition of bombesin-stimulated gastrin release from isolated canine G cells by bombesin antagonists. Canadian Journal of Physiology and Pharmacology. 67: 1520-4. PMID 2483358 DOI: 10.1139/Y89-245  0.373
1988 Brown JC, McIntosh CHS, Pederson RA. Gastric Inhibitory Polypeptide (GIP) Advances in Metabolic Disorders. 11: 321-331. DOI: 10.1016/B978-0-12-027311-9.50013-5  0.502
1987 Campos RV, Wheeler MB, Pederson RA, Buchan AMJ, Brown JC. The effect of total parenteral nutrition (TPN) on gastrin release in the rat Regulatory Peptides. 19: 281-289. PMID 3125565 DOI: 10.1016/0167-0115(87)90170-4  0.38
1987 Buchan A, Campos R, Walsh J, Pederson R. The role of gastrin releasing peptide in the hypergastrinemia of the obese zucker rat Regulatory Peptides. 19: 103. DOI: 10.1016/0167-0115(87)90083-8  0.317
1985 Pederson RA, Innis SM, Buchan AMJ, Chan CB, Brown JC. The effect of total parenteral nutrition (TPN) on the enteroinsular axis in the rat Regulatory Peptides. 10: 199-206. PMID 3922014 DOI: 10.1016/0167-0115(85)90014-X  0.581
1985 Buchan AM, Green KA, Innis SM, Pederson RA. The effect of total parenteral nutrition in the rat on a sub-group of enteroendocrine cells. Regulatory Peptides. 11: 347-52. PMID 2864721 DOI: 10.1016/0167-0115(85)90206-X  0.347
1985 Kwok YN, McIntosh CHS, Pederson RA, Brown JC. Effect of substance P on somatostatin release from the isolated perfused rat stomach Gastroenterology. 88: 90-95. PMID 2578040 DOI: 10.1016/0022-4731(84)90903-8  0.318
1984 Chan CB, Pederson RA, Buchan AMJ. Gastric inhibitory polypeptide (GIP) and insulin release in the obese Zucker rat Diabetes. 33: 536-542. PMID 6373459 DOI: 10.2337/Diab.33.6.536  0.489
1984 Müller MK, Demol P, Fladrich G, Goebell H, Pederson RA. Glucose-dependent insulinotropic action of cholecystokinin octapeptide in the isolated perfused rat pancreas. Digestion. 27: 245-51. PMID 6317502 DOI: 10.1159/000198960  0.459
1984 Koop H, Behrens I, Bothe E, Koschwitz H, McIntosh CH, Pederson RA, Arnold R, Creutzfeldt W. Adrenergic control of rat gastric somatostatin and gastrin release. Scandinavian Journal of Gastroenterology. 18: 65-71. PMID 6144172 DOI: 10.3109/00365528309181561  0.392
1983 Buchan AMJ, Pederson RA, Chan CB, Brown JC. The effect of massive small bowel resection (MSBR) and small intestinal bypass (JIB) in the rat on the enteroinsular axis Regulatory Peptides. 7: 221-232. PMID 6364262 DOI: 10.1016/0167-0115(83)90015-0  0.555
1983 Brown JC, McIntosh CH, Pederson RA. The gastrointestinal peptides and nutrition. Canadian Journal of Physiology and Pharmacology. 61: 282-9. PMID 6340809 DOI: 10.1139/Y83-043  0.357
1983 McIntosh CHS, Kwok YN, Mordhorst T, Nishimura E, Pederson RA, Brown JC. Enkephalinergic control of somatostatin secretion from the perfused rat stomach Canadian Journal of Physiology and Pharmacology. 61: 657-663. PMID 6137272 DOI: 10.1139/Y83-102  0.381
1983 Koop H, Behrens I, Bothe E, McIntosh CH, Pederson RA, Arnold R, Creutzfeldt W. Adrenergic and cholinergic interactions in rat gastric somatostatin and gastrin release. Digestion. 25: 96-102. PMID 6129170 DOI: 10.1159/000198817  0.397
1983 Pederson R, LeDuc C, Zahedi-Asl S, Buchan A, Brown J. GIP and insulin release in the obese Zucker rat Regulatory Peptides. 5: 58-59. DOI: 10.1016/0167-0115(83)90708-5  0.42
1982 Mueller MK, Pederson RA, Brown JC. Interaction of gastric inhibitory polypeptide and arginine with glucose in the perfused pancreas of rats treated with triidothyronine Canadian Journal of Physiology and Pharmacology. 60: 297-301. PMID 7042057 DOI: 10.1139/Y82-040  0.549
1982 Pederson RA, Buchan AMJ, Zahedi-Asl S, Chan CB, Brown JC. Effect of jejunoileal bypass in the rat on the enteroinsular axis Regulatory Peptides. 5: 53-63. PMID 6762622 DOI: 10.1016/0167-0115(82)90075-1  0.595
1981 Pederson R, O'Dorisio T, Howe B, McIntosh C, Mueller M, Brown J, Cataland S. Vagal release of IR-VIP and IR-gastrin from the isolated perfused rat stomach Molecular and Cellular Endocrinology. 23: 225-231. PMID 7274550 DOI: 10.1016/0303-7207(81)90072-1  0.344
1981 Brown JC, Dahl M, Kwauk S, McIntosh CHS, Otte SC, Pederson RA. Actions of GIP Peptides. 2: 241-245. PMID 7045829 DOI: 10.1016/0196-9781(81)90038-3  0.42
1981 McIntosh C, Pederson R, Müller M, Brown J. Autonomic nervous control of gastric somatostatin secretion from the perfused rat stomach Life Sciences. 29: 1477-1483. PMID 6117778 DOI: 10.1016/0024-3205(81)90013-8  0.349
1981 McIntosh CHS, Pederson RA, Koop H, Brown JC. Gastric inhibitory polypeptide stimulated secretion of somatostatinlike immunoreactivity from the stomach: Inhibition by acetylcholine or vagal stimulation Canadian Journal of Physiology and Pharmacology. 59: 468-472. PMID 6113043 DOI: 10.1139/Y81-069  0.369
1981 Pederson RA, McIntosh CHS, Mueller MK, Brown JC. Absence of a relationship between immunoreactive-gastrin and somatostatin-like immunoreactivity secretion in the perfused rat stomach Regulatory Peptides. 2: 53-60. PMID 6112781 DOI: 10.1016/0167-0115(81)90065-3  0.376
1980 Koop H, Behrens I, McIntosh CH, Pederson RA, Arnold R, Creutzfeldt W. Adrenergic modulation of gastric somatostatin release in rats. Febs Letters. 118: 248-50. PMID 6106559 DOI: 10.1016/0014-5793(80)80230-4  0.347
1980 Koop H, Behrens I, McIntosh C, Pederson R, Arnold R, Creutzfeldt W. Adrenergic modulation of rat gastric D-cell Regulatory Peptides. 1. DOI: 10.1016/0167-0115(80)90145-7  0.304
1979 Pederson RA, Brown JC. Interaction of gastric inhibitory polypeptide, glucose, and arginine on insulin and glucagon secretion from the perfused rat pancreas. Endocrinology. 103: 610-5. PMID 744105 DOI: 10.1210/Endo-103-2-610  0.576
1979 Pederson RA, Brown JC. Effect of cholecystokinin, secretin, and gastric inhibitory polypeptide on insulin release from the isolated perfused rat pancreas Canadian Journal of Physiology and Pharmacology. 57: 1233-1237. PMID 519526 DOI: 10.1139/Y79-186  0.549
1978 Brown JC, Dryburgh JR, Frost JL, Otte SC, Pederson RA. Physiology and pathophysiology of GIP Advances in Experimental Medicine and Biology. 106: 169-171. PMID 717160 DOI: 10.1007/978-1-4684-7248-6_21  0.548
1976 Pederson RA, Dryburgh JR, Brown JC. The effect of somatostatin on release and insulinotropic action of gastric inhibitory polypeptide. Canadian Journal of Physiology and Pharmacology. 53: 1200-5. PMID 1222389 DOI: 10.1139/Y75-168  0.491
1976 Pederson RA, Schubert HE, Brown JC. Gastric inhibitory polypeptide. Its physiologic release and insulinotropic action in the dog. Diabetes. 24: 1050-6. PMID 1193309 DOI: 10.2337/Diab.24.12.1050  0.516
1976 Pederson RA, Brown JC. The insulinotropic action of gastric inhibitory polypeptide in the perfused isolated rat pancreas. Endocrinology. 99: 780-5. PMID 954669 DOI: 10.1210/Endo-99-3-780  0.523
1975 Pederson RA, Schubert HE, Brown JC. The insulinotropic action of gastric inhibitory polypeptide. Canadian Journal of Physiology and Pharmacology. 53: 217-23. PMID 1137819 DOI: 10.1139/Y75-032  0.557
1972 Pederson RA, Brown JC. Inhibition of Histamine-, Pentagastrin-, and Insulin-Stimulated Canine Gastric Secretion by Pure “Gastric Inhibitory Polypeptide” Gastroenterology. 62: 393-400. DOI: 10.1016/S0016-5085(72)80144-6  0.408
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