| Year | Citation | Score | |||
|---|---|---|---|---|---|
| 2024 | Yang X, Zhang X, Ma Y, Li S, Wang Q, Hong JS, Yu G, Qi B, Wang J, Liu C, Shang Q, Wu X, Zhao J. Fucoidan ameliorates rotenone-induced Parkinsonism in mice by regulating the microbiota-gut-brain axis. International Journal of Biological Macromolecules. 137373. PMID 39521225 DOI: 10.1016/j.ijbiomac.2024.137373 | 0.512 | |||
| 2024 | Li S, Guo Z, Liu J, Ma Y, Zhang X, Hou L, Wang Q, Jiang W, Wang Q. CD11b-NOX2 mutual regulation-mediated microglial exosome release contributes to rotenone-induced inflammation and neurotoxicity in BV2 microglia and primary cultures. Free Radical Biology & Medicine. 224: 436-446. PMID 39265792 DOI: 10.1016/j.freeradbiomed.2024.09.008 | 0.368 | |||
| 2024 | Sun Q, Wang Y, Hou L, Li S, Hong JS, Wang Q, Zhao J. Corrigendum to "Clozapine-N-oxide protects dopaminergic neurons against rotenone-induced neurotoxicity by preventing ferritinophagy-mediated ferroptosis" [Free Radic. Biol. Med. 212 (2024) 384-402]. Free Radical Biology & Medicine. 215: 1. PMID 38408401 DOI: 10.1016/j.freeradbiomed.2024.02.007 | 0.469 | |||
| 2024 | Sun Q, Wang Y, Hou L, Li S, Hong JS, Wang Q, Zhao J. Clozapine-N-oxide protects dopaminergic neurons against rotenone-induced neurotoxicity by preventing ferritinophagy-mediated ferroptosis. Free Radical Biology & Medicine. PMID 38182072 DOI: 10.1016/j.freeradbiomed.2023.12.045 | 0.559 | |||
| 2023 | Yang JJ, Liu YX, Wang YF, Ge BY, Wang Y, Wang QS, Li S, Zhang JJ, Jin LL, Hong JS, Yin SM, Zhao J. Anti-epileptic and Neuroprotective Effects of Ultra-low Dose NADPH Oxidase Inhibitor Dextromethorphan on Kainic Acid-induced Chronic Temporal Lobe Epilepsy in Rats. Neuroscience Bulletin. PMID 37973720 DOI: 10.1007/s12264-023-01140-8 | 0.462 | |||
| 2023 | Wang Q, Ruan Z, Jing L, Guo Z, Zhang X, Liu J, Tian L, Sun W, Song S, Hong JS, Shih YI, Hou L, Wang Q. Complement receptor 3-mediated neurotoxic glial activation contributes to rotenone-induced cognitive decline in mice. Ecotoxicology and Environmental Safety. 266: 115550. PMID 37832486 DOI: 10.1016/j.ecoenv.2023.115550 | 0.455 | |||
| 2023 | Zhou R, Chen SH, Zhao Z, Tu D, Song S, Wang Y, Wang Q, Feng J, Hong JS. Complement C3 Enhances LPS-Elicited Neuroinflammation and Neurodegeneration Via the Mac1/NOX2 Pathway. Molecular Neurobiology. PMID 37268807 DOI: 10.1007/s12035-023-03393-w | 0.5 | |||
| 2023 | Song S, Tu D, Meng C, Liu J, Wilson B, Wang Q, Shih YI, Gao HM, Hong JS. Dysfunction of the noradrenergic system drives inflammation, α-synucleinopathy, and neuronal loss in mouse colon. Frontiers in Immunology. 14: 1083513. PMID 36845109 DOI: 10.3389/fimmu.2023.1083513 | 0.513 | |||
| 2022 | Zhang X, Tu D, Li S, Li N, Li D, Gao Y, Tian L, Liu J, Zhang X, Hong JS, Hou L, Zhao J, Wang Q. A novel synthetic peptide SVHRSP attenuates dopaminergic neurodegeneration by inhibiting NADPH oxidase-mediated neuroinflammation in experimental models of Parkinson's disease. Free Radical Biology & Medicine. PMID 35760232 DOI: 10.1016/j.freeradbiomed.2022.06.241 | 0.562 | |||
| 2022 | Ruan Z, Zhang D, Huang R, Sun W, Hou L, Zhao J, Wang Q. Microglial Activation Damages Dopaminergic Neurons through MMP-2/-9-Mediated Increase of Blood-Brain Barrier Permeability in a Parkinson's Disease Mouse Model. International Journal of Molecular Sciences. 23. PMID 35269933 DOI: 10.3390/ijms23052793 | 0.352 | |||
| 2021 | Guo Z, Ruan Z, Zhang D, Liu X, Hou L, Wang Q. Rotenone impairs learning and memory in mice through microglia-mediated blood brain barrier disruption and neuronal apoptosis. Chemosphere. 132982. PMID 34822863 DOI: 10.1016/j.chemosphere.2021.132982 | 0.317 | |||
| 2021 | Hou L, Zhou X, Zhang C, Wang K, Liu X, Che Y, Sun F, Li H, Wang Q, Zhang D, Hong JS. Corrigendum to "NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease" [Redox Biol. 2017, 12: 162-170]. Redox Biology. 102119. PMID 34465554 DOI: 10.1016/j.redox.2021.102119 | 0.468 | |||
| 2021 | Qiu X, Wang Q, Hou L, Zhang C, Wang Q, Zhao X. Inhibition of NLRP3 inflammasome by glibenclamide attenuated dopaminergic neurodegeneration and motor deficits in paraquat and maneb-induced mouse Parkinson's disease model. Toxicology Letters. PMID 34052309 DOI: 10.1016/j.toxlet.2021.05.008 | 0.391 | |||
| 2021 | Jing L, Hou L, Zhang D, Li S, Ruan Z, Zhang X, Hong JS, Wang Q. Microglial Activation Mediates Noradrenergic Locus Coeruleus Neurodegeneration via Complement Receptor 3 in a Rotenone-Induced Parkinson's Disease Mouse Model. Journal of Inflammation Research. 14: 1341-1356. PMID 33859489 DOI: 10.2147/JIR.S299927 | 0.55 | |||
| 2021 | Zhang D, Li S, Hou L, Jing L, Ruan Z, Peng B, Zhang X, Hong JS, Zhao J, Wang Q. Microglial activation contributes to cognitive impairments in rotenone-induced mouse Parkinson's disease model. Journal of Neuroinflammation. 18: 4. PMID 33402167 DOI: 10.1186/s12974-020-02065-z | 0.463 | |||
| 2020 | Huang R, Hou L, Zhai X, Ruan Z, Sun W, Zhang D, Zhao X, Wang Q. 2,5-hexanedione induces NLRP3 inflammasome activation and neurotoxicity through NADPH oxidase-dependent pathway. Free Radical Biology & Medicine. PMID 33212186 DOI: 10.1016/j.freeradbiomed.2020.11.013 | 0.33 | |||
| 2020 | Hou L, Qu X, Qiu X, Huang R, Zhao X, Wang Q. Integrin CD11b mediates locus coeruleus noradrenergic neurodegeneration in a mouse Parkinson's disease model. Journal of Neuroinflammation. 17: 148. PMID 32375810 DOI: 10.1186/s12974-020-01823-3 | 0.332 | |||
| 2020 | Hou L, Zhang L, Hong JS, Zhang D, Zhao J, Wang Q. NADPH oxidase and neurodegenerative diseases: mechanisms and therapy. Antioxidants & Redox Signaling. PMID 31968994 DOI: 10.1089/Ars.2019.8014 | 0.443 | |||
| 2020 | Wang Q, Oyarzabal EA, Song S, Wilson B, Santos JH, Hong JS. Locus coeruleus neurons are most sensitive to chronic neuroinflammation-induced neurodegeneration. Brain, Behavior, and Immunity. PMID 31923552 DOI: 10.1016/J.Bbi.2020.01.003 | 0.546 | |||
| 2019 | Bao XQ, Wang L, Yang HY, Hou LY, Wang QS, Zhang D. Induction of glial cell line-derived neurotrophic factor by the squamosamide derivative FLZ in astroglia has neuroprotective effects on dopaminergic neurons. Brain Research Bulletin. PMID 31669104 DOI: 10.1016/j.brainresbull.2019.10.008 | 0.358 | |||
| 2019 | Hou L, Sun F, Sun W, Zhang L, Wang Q. Lesion of the locus coeruleus damages learning and memory performance in paraquat and maneb-induced mouse Parkinson's disease model. Neuroscience. PMID 31634513 DOI: 10.1016/j.neuroscience.2019.09.006 | 0.355 | |||
| 2019 | Song S, Wang Q, Jiang L, Oyarzabal E, Riddick NV, Wilson B, Moy SS, Shih YI, Hong JS. Noradrenergic dysfunction accelerates LPS-elicited inflammation-related ascending sequential neurodegeneration and deficits in non-motor/motor functions. Brain, Behavior, and Immunity. PMID 31247288 DOI: 10.1016/J.Bbi.2019.06.034 | 0.553 | |||
| 2019 | Hou L, Huang R, Sun F, Zhang L, Wang Q. NADPH oxidase regulates paraquat and maneb-induced dopaminergic neurodegeneration through ferroptosis. Toxicology. PMID 30797899 DOI: 10.1016/j.tox.2019.02.011 | 0.348 | |||
| 2018 | Song S, Jiang L, Oyarzabal EA, Wilson B, Li Z, Shih YI, Wang Q, Hong JS. Loss of Brain Norepinephrine Elicits Neuroinflammation-Mediated Oxidative Injury and Selective Caudo-Rostral Neurodegeneration. Molecular Neurobiology. PMID 30051353 DOI: 10.1007/S12035-018-1235-1 | 0.591 | |||
| 2018 | Hou L, Li Q, Jiang L, Qiu H, Geng C, Hong JS, Li H, Wang Q. Hypertension and Diagnosis of Parkinson's Disease: A Meta-Analysis of Cohort Studies. Frontiers in Neurology. 9: 162. PMID 29615961 DOI: 10.3389/Fneur.2018.00162 | 0.406 | |||
| 2018 | Che Y, Hou L, Sun F, Zhang C, Liu X, Piao F, Zhang D, Li H, Wang Q. Taurine protects dopaminergic neurons in a mouse Parkinson's disease model through inhibition of microglial M1 polarization. Cell Death & Disease. 9: 435. PMID 29568078 DOI: 10.1038/s41419-018-0468-2 | 0.4 | |||
| 2018 | Hou L, Che Y, Sun F, Wang Q. Taurine protects noradrenergic locus coeruleus neurons in a mouse Parkinson's disease model by inhibiting microglial M1 polarization. Amino Acids. PMID 29508060 DOI: 10.1007/s00726-018-2547-1 | 0.422 | |||
| 2018 | Chen SH, Sung YF, Oyarzabal EA, Tan YM, Leonard J, Guo M, Li S, Wang Q, Chu CH, Chen SL, Lu RB, Hong JS. Physiological Concentration of Prostaglandin EExerts Anti-inflammatory Effects by Inhibiting Microglial Production of Superoxide Through a Novel Pathway. Molecular Neurobiology. PMID 29492849 DOI: 10.1007/S12035-018-0965-4 | 0.586 | |||
| 2018 | Zhang C, Hou L, Yang J, Che Y, Sun F, Li H, Wang Q. 2,5-Hexanedione induces dopaminergic neurodegeneration through integrin αMβ2/NADPH oxidase axis-mediated microglial activation. Cell Death & Disease. 9: 60. PMID 29352205 DOI: 10.1038/s41419-017-0091-7 | 0.365 | |||
| 2017 | Hou L, Wang K, Zhang C, Sun F, Che Y, Zhao X, Zhang D, Li H, Wang Q. Complement receptor 3 mediates NADPH oxidase activation and dopaminergic neurodegeneration through a Src-Erk-dependent pathway. Redox Biology. 14: 250-260. PMID 28978491 DOI: 10.1016/j.redox.2017.09.017 | 0.324 | |||
| 2017 | Hou L, Zhou X, Zhang C, Wang K, Liu X, Che Y, Sun F, Li H, Wang Q, Zhang D, Hong JS. NADPH oxidase-derived H2O2 mediates the regulatory effects of microglia on astrogliosis in experimental models of Parkinson's disease. Redox Biology. 12: 162-170. PMID 28237879 DOI: 10.1016/J.Redox.2017.02.016 | 0.537 | |||
| 2017 | Hou L, Zhang C, Wang K, Liu X, Wang H, Che Y, Sun F, Zhou X, Zhao X, Wang Q. Paraquat and maneb co-exposure induces noradrenergic locus coeruleus neurodegeneration through NADPH oxidase-mediated microglial activation. Toxicology. PMID 28202386 DOI: 10.1016/j.tox.2017.02.009 | 0.406 | |||
| 2016 | Jiang L, Wu X, Wang S, Chen SH, Zhou H, Wilson B, Jin CY, Lu RB, Xie K, Wang Q, Hong JS. Clozapine metabolites protect dopaminergic neurons through inhibition of microglial NADPH oxidase. Journal of Neuroinflammation. 13: 110. PMID 27184631 DOI: 10.1186/s12974-016-0573-z | 0.46 | |||
| 2016 | Chu CH, Wang S, Li CL, Chen SH, Hu CF, Chung YL, Chen SL, Wang Q, Lu RB, Gao HM, Hong JS. Neurons and astroglia govern microglial endotoxin tolerance through macrophage colony-stimulating factor receptor-mediated ERK1/2 signals. Brain, Behavior, and Immunity. PMID 27132056 DOI: 10.1016/J.Bbi.2016.04.015 | 0.53 | |||
| 2015 | Wang Q, Oyarzabal E, Wilson B, Qian L, Hong JS. Substance P enhances microglial density in the substantia nigra through neurokinin-1 receptor/NADPH oxidase-mediated chemotaxis in mice. Clinical Science (London, England : 1979). 129: 757-67. PMID 26223840 DOI: 10.1042/Cs20150008 | 0.483 | |||
| 2015 | Jiang L, Chen SH, Chu CH, Wang SJ, Oyarzabal E, Wilson B, Sanders V, Xie K, Wang Q, Hong JS. A novel role of microglial NADPH oxidase in mediating extra-synaptic function of norepinephrine in regulating brain immune homeostasis. Glia. 63: 1057-72. PMID 25740080 DOI: 10.1002/Glia.22801 | 0.601 | |||
| 2015 | Wang Q, Qian L, Chen SH, Chu CH, Wilson B, Oyarzabal E, Ali S, Robinson B, Rao D, Hong JS. Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models. Brain : a Journal of Neurology. 138: 1247-62. PMID 25716193 DOI: 10.1093/Brain/Awv034 | 0.587 | |||
| 2015 | Chu CH, Chen SH, Wang Q, Langenbach R, Li H, Zeldin D, Chen SL, Wang S, Gao H, Lu RB, Hong JS. PGE2 Inhibits IL-10 Production via EP2-Mediated β-Arrestin Signaling in Neuroinflammatory Condition. Molecular Neurobiology. 52: 587-600. PMID 25218510 DOI: 10.1007/S12035-014-8889-0 | 0.476 | |||
| 2015 | Chen SH, Oyarzabal EA, Sung YF, Chu CH, Wang Q, Chen SL, Lu RB, Hong JS. Microglial regulation of immunological and neuroprotective functions of astroglia. Glia. 63: 118-31. PMID 25130274 DOI: 10.1002/Glia.22738 | 0.556 | |||
| 2014 | Wang Q, Chu CH, Qian L, Chen SH, Wilson B, Oyarzabal E, Jiang L, Ali S, Robinson B, Kim HC, Hong JS. Substance P exacerbates dopaminergic neurodegeneration through neurokinin-1 receptor-independent activation of microglial NADPH oxidase. The Journal of Neuroscience : the Official Journal of the Society For Neuroscience. 34: 12490-503. PMID 25209287 DOI: 10.1523/Jneurosci.2238-14.2014 | 0.546 | |||
| 2014 | Wang Q, Chu CH, Oyarzabal E, Jiang L, Chen SH, Wilson B, Qian L, Hong JS. Subpicomolar diphenyleneiodonium inhibits microglial NADPH oxidase with high specificity and shows great potential as a therapeutic agent for neurodegenerative diseases. Glia. 62: 2034-43. PMID 25043383 DOI: 10.1002/Glia.22724 | 0.582 | |||
| 2012 | Wang Q, Shin EJ, Nguyen XK, Li Q, Bach JH, Bing G, Kim WK, Kim HC, Hong JS. Endogenous dynorphin protects against neurotoxin-elicited nigrostriatal dopaminergic neuron damage and motor deficits in mice. Journal of Neuroinflammation. 9: 124. PMID 22695044 DOI: 10.1186/1742-2094-9-124 | 0.587 | |||
| 2012 | Wang Q, Zhou H, Gao H, Chen SH, Chu CH, Wilson B, Hong JS. Naloxone inhibits immune cell function by suppressing superoxide production through a direct interaction with gp91phox subunit of NADPH oxidase. Journal of Neuroinflammation. 9: 32. PMID 22340895 DOI: 10.1186/1742-2094-9-32 | 0.509 | |||
| 2012 | Chen SH, Wu HM, Ossola B, Schendzielorz N, Wilson BC, Chu CH, Chen SL, Wang Q, Zhang D, Qian L, Li X, Hong JS, Lu RB. Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, protects dopaminergic neurons from neurotoxin-induced damage. British Journal of Pharmacology. 165: 494-505. PMID 21726209 DOI: 10.1111/J.1476-5381.2011.01575.X | 0.557 | |||
| 2011 | Wang Q, Song F, Zhang C, Zhao X, Zhu Z, Yu S, Xie K. Carboxyl-terminus of Hsc70 interacting protein mediates 2,5-hexanedione-induced neurofilament medium chain degradation. Biochemical Pharmacology. 81: 793-9. PMID 21219885 DOI: 10.1016/J.Bcp.2010.12.021 | 0.349 | |||
| 2009 | Song F, Zhang C, Wang Q, Zeng T, Xie K. Alterations in neurofilaments content and calpains activity of sciatic nerve of carbon disulfide-treated rats. Archives of Toxicology. 83: 587-94. PMID 19165470 DOI: 10.1007/S00204-008-0399-2 | 0.33 | |||
| 2008 | Wang QS, Hou LY, Zhang CL, Zhao XL, Yu SF, Xie KQ. 2,5-hexanedione (HD) treatment alters calmodulin, Ca2+/calmodulin-dependent protein kinase II, and protein kinase C in rats' nerve tissues. Toxicology and Applied Pharmacology. 232: 60-8. PMID 18582483 DOI: 10.1016/J.Taap.2008.05.021 | 0.327 | |||
| 2008 | Zhu YJ, Zeng T, Zhu YB, Yu SF, Wang QS, Zhang LP, Guo X, Xie KQ. Effects of acrylamide on the nervous tissue antioxidant system and sciatic nerve electrophysiology in the rat. Neurochemical Research. 33: 2310-7. PMID 18470611 DOI: 10.1007/S11064-008-9730-9 | 0.329 | |||
| 2008 | Wang QS, Zhang CL, Hou LY, Zhao XL, Yang XW, Xie KQ. Involvement of cyclin-dependent kinase 5 in 2,5-hexanedione-induced neuropathy. Toxicology. 248: 1-7. PMID 18423835 DOI: 10.1016/J.Tox.2008.02.019 | 0.336 | |||
| 2008 | Wang Q, Hou L, Zhang C, Song F, Xie K. Changes of cytoskeletal proteins in nerve tissues and serum of rats treated with 2,5-hexanedione Toxicology. 244: 166-178. PMID 18177991 DOI: 10.1016/J.Tox.2007.11.009 | 0.323 | |||
| 2008 | Song F, Yu S, Zhang C, Zhou G, Wang Q, Xie K. The reversibility of neurofilaments decline induced by 2,5-hexanedione in rat nerve tissues. Biochemical Pharmacology. 75: 737-44. PMID 18001694 DOI: 10.1016/J.Bcp.2007.10.001 | 0.335 | |||
| 2008 | Gao X, Zeng T, Wang Q, Wang Q, Xie K. [Effects of garlic oil on 2, 5-HD induced lipid peroxidation damage in rat nerve tissues]. Chinese Journal of Industrial Hygiene and Occupational Diseases. 26: 649-653. DOI: 10.3760/Cma.J.Issn.1001-9391.2008.11.003 | 0.328 | |||
| 2008 | Song F, Wang Q, Zeng T, Yu L, Zhu Z, Xie K. [Dynamic study of neurofilament contents in rat's spinal cord induced by 2, 5-hexanedione]. Chinese Journal of Industrial Hygiene and Occupational Diseases. 26: 588-591. DOI: 10.3760/Cma.J.Issn.1001-9391.2008.10.003 | 0.34 | |||
| 2008 | Wang Q, Hou L, Zhang C, Zeng T, Yang X, Xie K. [Expression changes of cyclin dependent kinase 5/p35 in nerve tissues of 2, 5-hexanedione intoxicated rats]. Chinese Journal of Industrial Hygiene and Occupational Diseases. 26: 336-340. DOI: 10.3760/Cma.J.Issn.1001-9391.2008.06.005 | 0.305 | |||
| 2007 | Zhang LP, Wang QS, Guo X, Zhu YJ, Zhou GZ, Xie KQ. Time-dependent changes of lipid peroxidation and antioxidative status in nerve tissues of hens treated with tri-ortho-cresyl phosphate (TOCP). Toxicology. 239: 45-52. PMID 17662514 DOI: 10.1016/J.Tox.2007.06.091 | 0.323 | |||
| 2007 | Wang Q, Song F, Zhao X, Hou L, Xie K. Expression changes of apoptotic-related proteins in nerve tissues of rats treated with allyl chloride Toxicology. 231: 58-67. PMID 17194518 DOI: 10.1016/J.Tox.2006.11.071 | 0.309 | |||
| 2006 | Wang Q, Zhang C, Zhao X, Yu S, Xie K. Malondialdehyde and catalase as the serum biomarkers of allyl chloride-induced toxic neuropathy. Toxicology. 227: 36-44. PMID 16938375 DOI: 10.1016/J.Tox.2006.07.006 | 0.327 | |||
| 2006 | Wang QS, Xie KQ, Zhang CL, Zhu YJ, Zhang LP, Guo X, Yu SF. Allyl chloride-induced time dependent changes of lipid peroxidation in rat nerve tissue. Neurochemical Research. 30: 1387-95. PMID 16341935 DOI: 10.1007/S11064-005-8391-1 | 0.321 | |||
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