Yorgo E. Modis - Publications

Affiliations: 
Molecular Biophysics and Biochemistry Yale University, New Haven, CT 
Area:
molecular mechanisms of host-pathogen interactions using X-ray crystallography, microscopy, and other biophysical and biochemical approaches
Website:
http://medicine.yale.edu/mbb/faculty/yorgo_modis.profile

50/89 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Pokorny L, Burden JJ, Albrecht D, Bamford R, Leigh KE, Sridhar P, Knowles TJ, Modis Y, Mercer J. The vaccinia chondroitin sulfate binding protein drives host membrane curvature to facilitate fusion. Embo Reports. PMID 38321165 DOI: 10.1038/s44319-023-00040-2  0.306
2024 Stoll GA, Nikolopoulos N, Zhai H, Zhang L, Douse CH, Modis Y. Crystal structure and biochemical activity of the macrodomain from rubella virus p150. Journal of Virology. e0177723. PMID 38289106 DOI: 10.1128/jvi.01777-23  0.349
2019 Hwang MS, Boulanger J, Howe JD, Albecka A, Pasche M, Mureşan L, Modis Y. MAVS polymers smaller than 80 nm induce mitochondrial membrane remodeling and interferon signaling. The Febs Journal. PMID 30715798 DOI: 10.1111/Febs.14772  0.347
2019 Stoll GA, Oda S, Chong Z, Yu M, McLaughlin SH, Modis Y. Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing Proceedings of the National Academy of Sciences of the United States of America. 116: 15042-15051. DOI: 10.2210/Pdb6Qaj/Pdb  0.389
2018 Douse CH, Bloor S, Liu Y, Shamin M, Tchasovnikarova IA, Timms RT, Lehner PJ, Modis Y. Neuropathic MORC2 mutations perturb GHKL ATPase dimerization dynamics and epigenetic silencing by multiple structural mechanisms. Nature Communications. 9: 651. PMID 29440755 DOI: 10.1038/S41467-018-03045-X  0.373
2018 Yu Q, Qu K, Modis Y. Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Molecular Cell. 72: 999. DOI: 10.2210/Pdb6G1X/Pdb  0.399
2017 Fenwick MK, Li Y, Cresswell P, Modis Y, Ealick SE. Structural studies of viperin, an antiviral radical SAM enzyme. Proceedings of the National Academy of Sciences of the United States of America. PMID 28607080 DOI: 10.1073/Pnas.1705402114  0.382
2016 Willensky S, Bar-Rogovsky H, Bignon EA, Tischler ND, Modis YE, Dessau M. Crystal Structure of Glycoprotein C from a Hantavirus in the Post-fusion Conformation. Plos Pathogens. 12. PMID 27783673 DOI: 10.1371/Journal.Ppat.1005948  0.754
2016 Meyer PA, Socias S, Key J, Ransey E, Tjon EC, Buschiazzo A, Lei M, Botka C, Withrow J, Neau D, Rajashankar K, Anderson KS, Baxter RH, Blacklow SC, Boggon TJ, ... ... Modis Y, et al. Data publication with the structural biology data grid supports live analysis. Nature Communications. 7: 10882. PMID 26947396 DOI: 10.1038/Ncomms10882  0.716
2015 Esposito DL, Nguyen JB, DeWitt DC, Rhoades E, Modis Y. Physicochemical requirements and kinetics of membrane fusion of flavivirus-like particles. The Journal of General Virology. PMID 25740960 DOI: 10.1099/Vir.0.000113  0.611
2014 Reikine S, Nguyen JB, Modis Y. Pattern Recognition and Signaling Mechanisms of RIG-I and MDA5. Frontiers in Immunology. 5: 342. PMID 25101084 DOI: 10.3389/Fimmu.2014.00342  0.598
2014 Wang J, Li Y, Modis Y. Exploiting subtle structural differences in heavy-atom derivatives for experimental phasing. Acta Crystallographica Section D-Biological Crystallography. 70: 1873-1883. PMID 25004964 DOI: 10.1107/S1399004714008943  0.357
2014 Nour AM, Modis Y. Endosomal vesicles as vehicles for viral genomes. Trends in Cell Biology. 24: 449-54. PMID 24746011 DOI: 10.1016/J.Tcb.2014.03.006  0.337
2014 Wang J, Li Y, Modis Y. Structural models of the membrane anchors of envelope glycoproteins E1 and E2 from pestiviruses Virology. 454: 93-101. PMID 24725935 DOI: 10.1016/J.Virol.2014.02.015  0.381
2014 Li Y, Modis Y. A novel membrane fusion protein family in Flaviviridae Trends in Microbiology. 22: 176-182. PMID 24569295 DOI: 10.1016/J.Tim.2014.01.008  0.443
2014 Modis Y. Relating structure to evolution in class II viral membrane fusion proteins Current Opinion in Virology. 5: 34-41. PMID 24525225 DOI: 10.1016/J.Coviro.2014.01.009  0.395
2013 Nour AM, Li Y, Wolenski J, Modis Y. Viral membrane fusion and nucleocapsid delivery into the cytoplasm are distinct events in some flaviviruses. Plos Pathogens. 9: e1003585. PMID 24039574 DOI: 10.1371/Journal.Ppat.1003585  0.378
2013 Nguyen JB, Pool CD, Wong CY, Treger RS, Williams DL, Cappello M, Lea WA, Simeonov A, Vermeire JJ, Modis Y. Peroxiredoxin-1 from the human hookworm Ancylostoma ceylanicum forms a stable oxidized decamer and is covalently inhibited by conoidin A. Chemistry & Biology. 20: 991-1001. PMID 23891152 DOI: 10.1016/J.Chembiol.2013.06.011  0.602
2013 Modis Y. Class II fusion proteins. Advances in Experimental Medicine and Biology. 790: 150-166. PMID 23884590 DOI: 10.1007/978-1-4614-7651-1_8  0.435
2013 Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H. Utilizing protein structure to identify non-random somatic mutations Bmc Bioinformatics. 14. PMID 23758891 DOI: 10.1186/1471-2105-14-190  0.301
2013 Li Y, Wang J, Kanai R, Modis Y. Crystal structure of glycoprotein E2 from bovine viral diarrhea virus. Proceedings of the National Academy of Sciences of the United States of America. 110: 6805-10. PMID 23569276 DOI: 10.1073/Pnas.1300524110  0.463
2013 Hakim A, Nguyen JB, Basu K, Zhu DF, Thakral D, Davies PL, Isaacs FJ, Modis Y, Meng W. Crystal structure of an insect antifreeze protein and its implications for ice binding. The Journal of Biological Chemistry. 288: 12295-304. PMID 23486477 DOI: 10.1074/Jbc.M113.450973  0.607
2013 Dessau M, Modis Y. Crystal structure of glycoprotein C from Rift Valley fever virus Proceedings of the National Academy of Sciences of the United States of America. 110: 1696-1701. PMID 23319635 DOI: 10.1073/Pnas.1217780110  0.758
2013 Berke IC, Li Y, Modis Y. Structural basis of innate immune recognition of viral RNA. Cellular Microbiology. 15: 386-394. PMID 23110455 DOI: 10.1111/Cmi.12061  0.318
2013 Nguyen JB, Modis Y. Crystal structure of the dimeric coiled-coil domain of the cytosolic nucleic acid sensor LRRFIP1. Journal of Structural Biology. 181: 82-8. PMID 23099021 DOI: 10.1016/J.Jsb.2012.10.006  0.614
2013 Dessau M, Modis Y. Crystal structure of glycoprotein C from Rift Valley fever virus F1000research. 4. DOI: 10.7490/F1000Research.1092907.1  0.726
2012 Dessau M, Goldhill D, McBride R, McBride RL, Turner PE, Modis Y. Selective pressure causes an RNA virus to trade reproductive fitness for increased structural and thermal stability of a viral enzyme. Plos Genetics. 8: e1003102. PMID 23209446 DOI: 10.1371/Journal.Pgen.1003102  0.718
2012 Berke IC, Yu X, Modis Y, Egelman EH. MDA5 assembles into a polar helical filament on dsRNA. Proceedings of the National Academy of Sciences of the United States of America. 109: 18437-41. PMID 23090998 DOI: 10.1073/Pnas.1212186109  0.35
2012 Duan X, Li Y, Rajan NK, Routenberg DA, Modis Y, Reed MA. Quantification of the affinities and kinetics of protein interactions using silicon nanowire biosensors. Nature Nanotechnology. 7: 401-7. PMID 22635097 DOI: 10.1038/Nnano.2012.82  0.306
2012 Modis Y. Exploiting structural biology in the fight against parasitic diseases. Trends in Parasitology. 28: 124-130. PMID 22341779 DOI: 10.1016/J.Pt.2012.01.003  0.312
2012 Berke IC, Modis Y. MDA5 cooperatively forms dimers and ATP-sensitive filaments upon binding double-stranded RNA. The Embo Journal. 31: 1714-1726. PMID 22314235 DOI: 10.1038/Emboj.2012.19  0.348
2012 Zhou K, Kanai R, Lee P, Wang HW, Modis Y. Toll-like receptor 5 forms asymmetric dimers in the absence of flagellin. Journal of Structural Biology. 177: 402-9. PMID 22173220 DOI: 10.1016/J.Jsb.2011.12.002  0.347
2011 Kucera K, Harrison LM, Cappello M, Modis Y. Ancylostoma ceylanicum excretory-secretory protein 2 adopts a netrin-like fold and defines a novel family of nematode proteins. Journal of Molecular Biology. 408: 9-17. PMID 21352830 DOI: 10.1016/J.Jmb.2011.02.033  0.651
2011 Dessau MA, Modis Y. Protein crystallization for X-ray crystallography. Journal of Visualized Experiments. 190-195. PMID 21304455 DOI: 10.3791/2285  0.713
2010 Kucera K, Koblansky AA, Saunders LP, Frederick KB, De La Cruz EM, Ghosh S, Modis Y. Structure-based analysis of Toxoplasma gondii profilin: a parasite-specific motif is required for recognition by Toll-like receptor 11. Journal of Molecular Biology. 403: 616-29. PMID 20851125 DOI: 10.1016/J.Jmb.2010.09.022  0.617
2009 Nayak V, Dessau M, Kucera K, Anthony K, Ledizet M, Modis Y. Crystal structure of dengue virus type 1 envelope protein in the postfusion conformation and its implications for membrane fusion. Journal of Virology. 83: 4338-44. PMID 19244332 DOI: 10.1128/Jvi.02574-08  0.777
2008 Modis Y. How influenza virus is locked out of the cell Proceedings of the National Academy of Sciences of the United States of America. 105: 18647-18648. PMID 19033206 DOI: 10.1073/Pnas.0810508106  0.393
2007 Arjona A, Ledizet M, Anthony K, Bonafé N, Modis Y, Town T, Fikrig E. West Nile virus envelope protein inhibits dsRNA-induced innate immune responses. Journal of Immunology (Baltimore, Md. : 1950). 179: 8403-9. PMID 18056386 DOI: 10.4049/Jimmunol.179.12.8403  0.37
2006 Kanai R, Kar K, Anthony K, Gould LH, Ledizet M, Fikrig E, Marasco WA, Koski RA, Modis Y. Crystal structure of west nile virus envelope glycoprotein reveals viral surface epitopes. Journal of Virology. 80: 11000-8. PMID 16943291 DOI: 10.1128/Jvi.01735-06  0.459
2005 Modis Y, Ogata S, Clements D, Harrison SC. Variable surface epitopes in the crystal structure of dengue virus type 3 envelope glycoprotein. Journal of Virology. 79: 1223-31. PMID 15613349 DOI: 10.1128/Jvi.79.2.1223-1231.2005  0.582
2004 Modis Y, Ogata S, Clements D, Harrison SC. Structure of the dengue virus envelope protein after membrane fusion. Nature. 427: 313-9. PMID 14737159 DOI: 10.1038/Nature02165  0.602
2004 Van den Berg B, Clemons WM, Collinson I, Modis Y, Hartmann E, Harrison SC, Rapoport TA. X-ray structure of a protein-conducting channel. Nature. 427: 36-44. PMID 14661030 DOI: 10.1038/Nature02218  0.537
2003 Modis Y, Ogata S, Clements D, Harrison SC. A ligand-binding pocket in the dengue virus envelope glycoprotein. Proceedings of the National Academy of Sciences of the United States of America. 100: 6986-91. PMID 12759475 DOI: 10.1073/Pnas.0832193100  0.59
2002 Modis Y, Trus BL, Harrison SC. Atomic model of the papillomavirus capsid. The Embo Journal. 21: 4754-62. PMID 12234916 DOI: 10.1093/Emboj/Cdf494  0.513
2002 Boll W, Rapoport I, Brunner C, Modis Y, Prehn S, Kirchhausen T. The mu2 subunit of the clathrin adaptor AP-2 binds to FDNPVY and YppØ sorting signals at distinct sites. Traffic (Copenhagen, Denmark). 3: 590-600. PMID 12121421 DOI: 10.1034/J.1600-0854.2002.30808.X  0.545
2000 Modis Y, Wierenga RK. Crystallographic analysis of the reaction pathway of Zoogloea ramigera biosynthetic thiolase. Journal of Molecular Biology. 297: 1171-82. PMID 10764581 DOI: 10.1006/Jmbi.2000.3638  0.579
1999 Modis Y, Wierenga RK. A biosynthetic thiolase in complex with a reaction intermediate: the crystal structure provides new insights into the catalytic mechanism. Structure (London, England : 1993). 7: 1279-90. PMID 10545327 DOI: 10.1016/S0969-2126(00)80061-1  0.607
1998 Modis Y, Wierenga R. Two crystal structures of N-acetyltransferases reveal a new fold for CoA-dependent enzymes Structure. 6: 1345-1350. PMID 9817851 DOI: 10.1016/S0969-2126(98)00134-8  0.583
1998 Modis Y, Filppula SA, Novikov DK, Norledge B, Hiltunen JK, Wierenga RK. The crystal structure of dienoyl-CoA isomerase at 1.5 A resolution reveals the importance of aspartate and glutamate sidechains for catalysis. Structure (London, England : 1993). 6: 957-70. PMID 9739087 DOI: 10.1016/S0969-2126(98)00098-7  0.616
1997 Mathieu M, Modis Y, Zeelen JP, Engel CK, Abagyan RA, Ahlberg A, Rasmussen B, Lamzin VS, Kunau WH, Wierenga RK. The 1.8 A crystal structure of the dimeric peroxisomal 3-ketoacyl-CoA thiolase of Saccharomyces cerevisiae: implications for substrate binding and reaction mechanism. Journal of Molecular Biology. 273: 714-28. PMID 9402066 DOI: 10.1006/Jmbi.1997.1331  0.612
Low-probability matches (unlikely to be authored by this person)
2015 Zhang X, Li S, Modis Y, Li Z, Zhang J, Xia N, Zhao Q. Functional assessment and structural basis of antibody binding to human papillomavirus capsid. Reviews in Medical Virology. PMID 26676802 DOI: 10.1002/Rmv.1867  0.3
2010 Fogel AI, Li Y, Giza J, Wang Q, Lam TT, Modis Y, Biederer T. N-glycosylation at the SynCAM (synaptic cell adhesion molecule) immunoglobulin interface modulates synaptic adhesion. The Journal of Biological Chemistry. 285: 34864-74. PMID 20739279 DOI: 10.1074/Jbc.M110.120865  0.298
2016 Ryslik GA, Cheng Y, Modis Y, Zhao H. Leveraging protein quaternary structure to identify oncogenic driver mutations. Bmc Bioinformatics. 17: 137. PMID 27001666 DOI: 10.1186/S12859-016-0963-3  0.296
2018 Douse CH, Liu Y, Bloor S, Shamin M, Timms RT, Tchasovnikarova IA, Lehner PJ, Modis Y. Neuropathic mutations in MORC2 perturb GHKL ATPase dimerization dynamics and transcriptional control by multiple structural mechanisms Nature Communications. DOI: 10.2210/Pdb5Of9/Pdb  0.295
2013 Zhao Q, Li S, Yu H, Xia N, Modis Y. Virus-like particle-based human vaccines: quality assessment based on structural and functional properties Trends in Biotechnology. 31: 654-663. PMID 24125746 DOI: 10.1016/J.Tibtech.2013.09.002  0.288
2018 Yu Q, Qu K, Modis Y. Cryo-EM Structures of MDA5-dsRNA Filaments at Different Stages of ATP Hydrolysis. Molecular Cell. PMID 30449722 DOI: 10.1016/j.molcel.2018.10.012  0.285
2014 Rigby RE, Webb LM, Mackenzie KJ, Li Y, Leitch A, Reijns MA, Lundie RJ, Revuelta A, Davidson DJ, Diebold S, Modis Y, MacDonald AS, Jackson AP. RNA:DNA hybrids are a novel molecular pattern sensed by TLR9. The Embo Journal. 33: 542-58. PMID 24514026 DOI: 10.1002/Embj.201386117  0.284
2017 Tchasovnikarova IA, Timms RT, Douse CH, Roberts RC, Dougan G, Kingston RE, Modis Y, Lehner PJ. Hyperactivation of HUSH complex function by Charcot-Marie-Tooth disease mutation in MORC2. Nature Genetics. PMID 28581500 DOI: 10.1038/Ng.3878  0.283
2022 Merchant M, Mata CP, Liu Y, Zhai H, Protasio AV, Modis Y. A bioactive phlebovirus-like envelope protein in a hookworm endogenous virus. Science Advances. 8: eabj6894. PMID 35544562 DOI: 10.1126/sciadv.abj6894  0.283
2015 Kim E, Ilagan JO, Liang Y, Daubner GM, Lee SC, Ramakrishnan A, Li Y, Chung YR, Micol JB, Murphy ME, Cho H, Kim MK, Zebari AS, Aumann S, Park CY, ... ... Modis Y, et al. SRSF2 Mutations Contribute to Myelodysplasia by Mutant-Specific Effects on Exon Recognition. Cancer Cell. 27: 617-30. PMID 25965569 DOI: 10.1016/J.Ccell.2015.04.006  0.282
2015 Modis Y. An Inheritable variant of the innate immune receptor melanoma differentiation-associated gene 5 promotes clearance of hepatitis C virus. Hepatology. 61: 418-420. PMID 25212845 DOI: 10.1002/Hep.27439  0.28
2015 Wong EV, Cao W, Vörös J, Merchant M, Modis Y, Hackney DD, Montpetit B, De La Cruz EM. Pi release limits the intrinsic and RNA-stimulated ATPase cycles of DEAD-box protein 5 (Dbp5). Journal of Molecular Biology. PMID 26730886 DOI: 10.1016/J.Jmb.2015.12.018  0.278
2016 Prigozhin DM, Modis Y. Flunarizine arrests hepatitis C virus membrane fusion Hepatology. 63: 14-16. DOI: 10.1002/Hep.28224  0.278
2019 Stoll GA, Oda SI, Chong ZS, Yu M, McLaughlin SH, Modis Y. Structure of KAP1 tripartite motif identifies molecular interfaces required for retroelement silencing. Proceedings of the National Academy of Sciences of the United States of America. PMID 31289231 DOI: 10.1073/pnas.1901318116  0.272
2014 Ryslik GA, Cheng Y, Cheung KH, Modis Y, Zhao H. A graph theoretic approach to utilizing protein structure to identify non-random somatic mutations. Bmc Bioinformatics. 15: 86. PMID 24669769 DOI: 10.1186/1471-2105-15-86  0.27
2020 Reikine S, McLaughlin SH, Modis Y. Equilibrium Binding Model for CpG DNA-Dependent Dimerization of Toll-like Receptor 9 Ectodomain. Biochemistry. PMID 32818369 DOI: 10.1021/Acs.Biochem.0C00466  0.269
2012 Li Y, Berke IC, Modis Y. DNA binding to proteolytically activated TLR9 is sequence-independent and enhanced by DNA curvature. The Embo Journal. 31: 919-931. PMID 22258621 DOI: 10.1038/Emboj.2011.441  0.269
2020 Prigozhin DM, Douse CH, Farleigh LE, Albecka A, Tchasovnikarova IA, Timms RT, Oda SI, Adolf F, Freund SMV, Maslen S, Lehner PJ, Modis Y. Periphilin self-association underpins epigenetic silencing by the HUSH complex. Nucleic Acids Research. 48: 10313-10328. PMID 32976585 DOI: 10.1093/nar/gkaa785  0.267
2013 He CH, Lee CG, Dela Cruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, et al. Chitinase 3-like 1 regulates cellular and tissue responses via IL-13 receptor α2. Cell Reports. 4: 830-41. PMID 23972995 DOI: 10.1016/J.Celrep.2013.07.032  0.266
2012 Berke IC, Modis YE. The innate immune receptor MDA5 binds dsRNA cooperatively and forms ATP-sensitive filaments F1000research. 3. DOI: 10.7490/F1000Research.1089828.1  0.265
2014 Ryslik GA, Cheng Y, Cheung KH, Bjornson RD, Zelterman D, Modis Y, Zhao H. A spatial simulation approach to account for protein structure when identifying non-random somatic mutations. Bmc Bioinformatics. 15: 231. PMID 24990767 DOI: 10.1186/1471-2105-15-231  0.264
2020 Cader MZ, de Almeida Rodrigues RP, West JA, Sewell GW, Md-Ibrahim MN, Reikine S, Sirago G, Unger LW, Inglesias-Romero AB, Ramshorn K, Haag LM, Saveljeva S, Ebel JF, Rosenstiel P, Kaneider NC, ... ... Modis Y, et al. FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. Cell. 180: 278-295.e23. PMID 31978345 DOI: 10.1016/J.Cell.2019.12.017  0.258
2012 Zhao Q, Modis Y, High K, Towne V, Meng Y, Wang Y, Alexandroff J, Brown M, Carragher B, Potter CS, Abraham D, Wohlpart D, Kosinski M, Washabaugh MW, Sitrin RD. Disassembly and reassembly of human papillomavirus virus-like particles produces more virion-like antibody reactivity. Virology Journal. 9: 52. PMID 22356831 DOI: 10.1186/1743-422X-9-52  0.258
2019 Zhang Z, Gothe F, Pennamen P, James JR, McDonald D, Mata CP, Modis Y, Alazami AM, Acres M, Haller W, Bowen C, Döffinger R, Sinclair J, Brothers S, Zhang Y, et al. Human interleukin-2 receptor β mutations associated with defects in immunity and peripheral tolerance. The Journal of Experimental Medicine. PMID 31040185 DOI: 10.1084/Jem.20182304  0.243
2022 Stoll GA, Pandiloski N, Douse CH, Modis Y. Structure and functional mapping of the KRAB-KAP1 repressor complex. The Embo Journal. e111179. PMID 36341546 DOI: 10.15252/embj.2022111179  0.242
2015 He CH, Lee CG, DelaCruz CS, Lee CM, Zhou Y, Ahangari F, Ma B, Herzog EL, Rosenberg SA, Li Y, Nour AM, Parikh CR, Schmidt I, Modis Y, Cantley L, et al. Erratum to Chitinase 3-like 1 Regulates Cellular and Tissue Responses via IL-13 Receptor α2, [Cell Reports 4, 2013, 830-841] Cell Reports. 10. DOI: 10.1016/J.Celrep.2015.02.017  0.23
2018 Sng CCT, O'Byrne S, Prigozhin DM, Bauer MR, Harvey JC, Ruhle M, Challis BG, Lear S, Roberts LD, Workman S, Janowitz T, Magiera L, Doffinger R, Buckland MS, Jodrell DJ, ... ... Modis Y, et al. A Type III Complement Factor D Deficiency: Structural insights for inhibition of the alternative pathway. The Journal of Allergy and Clinical Immunology. PMID 29522842 DOI: 10.1016/J.Jaci.2018.01.048  0.228
2016 Lee CM, He CH, Nour AM, Zhou Y, Ma B, Park JW, Kim KH, Cruz CD, Sharma L, Nasr ML, Modis Y, Lee CG, Elias JA. Corrigendum: IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses. Nature Communications. 7: 13541. PMID 27841275 DOI: 10.1038/Ncomms13541  0.227
2020 Cader MZ, Rodrigues RPdA, West JA, Sewell GW, Md-Ibrahim MN, Reikine S, Sirago G, Unger LW, Romero ABI, Ramshorn K, Haag L-, Saveljeva S, Ebel J-, Rosenstiel P, Kaneider NC, ... ... Modis Y, et al. FAMIN is a purine nucleoside enzyme that paces cellular metabolism via the purine nucleotide cycle Cell. DOI: 10.2210/Pdb6T0Y/Pdb  0.223
2015 Prigozhin DM, Modis Y. Flunarizine arrests hepatitis C virus membrane fusion. Hepatology (Baltimore, Md.). 63: 14-6. PMID 26389725 DOI: 10.1002/hep.28224  0.217
2024 Singh R, Wu Y, Herrero Del Valle A, Leigh KE, Mong S, Cheng MTK, Ferguson BJ, Modis Y. Contrasting functions of ATP hydrolysis by MDA5 and LGP2 in viral RNA sensing. The Journal of Biological Chemistry. 105711. PMID 38309507 DOI: 10.1016/j.jbc.2024.105711  0.2
2021 Kemp SA, Collier DA, Datir RP, Ferreira IATM, Gayed S, Jahun A, Hosmillo M, Rees-Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N, ... ... Modis Y, et al. SARS-CoV-2 evolution during treatment of chronic infection. Nature. PMID 33545711 DOI: 10.1038/s41586-021-03291-y  0.195
2021 Yu Q, Herrero Del Valle A, Singh R, Modis Y. MDA5 disease variant M854K prevents ATP-dependent structural discrimination of viral and cellular RNA. Nature Communications. 12: 6668. PMID 34795277 DOI: 10.1038/s41467-021-27062-5  0.182
2023 Liu Y, Zhai H, Alemayehu H, Boulanger J, Hopkins LJ, Borgeaud AC, Heroven C, Howe JD, Leigh KE, Bryant CE, Modis Y. Cryo-electron tomography of NLRP3-activated ASC complexes reveals organelle co-localization. Nature Communications. 14: 7246. PMID 37945612 DOI: 10.1038/s41467-023-43180-8  0.15
2020 Douse CH, Tchasovnikarova IA, Timms RT, Protasio AV, Seczynska M, Prigozhin DM, Albecka A, Wagstaff J, Williamson JC, Freund SMV, Lehner PJ, Modis Y. TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control. Nature Communications. 11: 4940. PMID 33009411 DOI: 10.1038/s41467-020-18761-6  0.14
2021 Leigh KE, Modis Y. Imaging and visualizing SARS-CoV-2 in a new era for structural biology. Interface Focus. 11: 20210019. PMID 34956593 DOI: 10.1098/rsfs.2021.0019  0.136
2016 Lee CM, He CH, Nour AM, Zhou Y, Ma B, Park JW, Kim KH, Cruz CD, Sharma L, Nasr ML, Modis Y, Lee CG, Elias JA. IL-13Rα2 uses TMEM219 in chitinase 3-like-1-induced signalling and effector responses. Nature Communications. 7: 12752. PMID 27629921 DOI: 10.1038/Ncomms12752  0.106
2020 Cader MZ, de Almeida Rodrigues RP, West JA, Sewell GW, Md-Ibrahim MN, Reikine S, Sirago G, Unger LW, Iglesias-Romero AB, Ramshorn K, Haag LM, Saveljeva S, Ebel JF, Rosenstiel P, Kaneider NC, ... ... Modis Y, et al. FAMIN Is a Multifunctional Purine Enzyme Enabling the Purine Nucleotide Cycle. Cell. 180: 815. PMID 32084343 DOI: 10.1016/j.cell.2020.02.005  0.077
2022 Kemp SA, Collier DA, Datir RP, Ferreira IATM, Gayed S, Jahun A, Hosmillo M, Rees-Spear C, Mlcochova P, Lumb IU, Roberts DJ, Chandra A, Temperton N, Sharrocks K, Blane E, ... Modis Y, et al. Author Correction: SARS-CoV-2 evolution during treatment of chronic infection. Nature. PMID 35864233 DOI: 10.1038/s41586-022-05104-2  0.045
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