Phillip J. Buckhaults - Publications

Affiliations: 
Drug Discovery & Biomedical Sciences University of South Carolina, Columbia, SC 

44 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 Vu T, Datta A, Banister C, Jin L, Yuan G, Samuel T, Bae S, Eltoum IE, Manne U, Zhang B, Welner RS, Mitra K, Buckhaults P, Datta PK. STRAP is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis through a Feed-Forward Mechanism. Gastroenterology. PMID 34520730 DOI: 10.1053/j.gastro.2021.09.010  0.369
2020 Hofseth LJ, Hebert JR, Chanda A, Chen H, Love BL, Pena MM, Murphy EA, Sajish M, Sheth A, Buckhaults PJ, Berger FG. Publisher Correction: Early-onset colorectal cancer: initial clues and current views. Nature Reviews. Gastroenterology & Hepatology. PMID 32601393 DOI: 10.1038/S41575-020-0338-0  0.416
2020 Saatci O, Kaymak A, Raza U, Ersan PG, Akbulut O, Banister CE, Sikirzhytski V, Tokat UM, Aykut G, Ansari SA, Dogan HT, Dogan M, Jandaghi P, Isik A, Gundogdu F, ... ... Buckhaults PJ, et al. Targeting lysyl oxidase (LOX) overcomes chemotherapy resistance in triple negative breast cancer. Nature Communications. 11: 2416. PMID 32415208 DOI: 10.1038/S41467-020-16199-4  0.453
2020 Kundu A, Nam H, Shelar S, Chandrashekar DS, Brinkley G, Karki S, Mitchell T, Livi CB, Buckhaults P, Kirkman R, Tang Y, Rowe GC, Wei S, Varambally S, Sudarshan S. PRDM16 suppresses HIF-targeted gene expression in kidney cancer. The Journal of Experimental Medicine. 217. PMID 32251515 DOI: 10.1084/Jem.20191005  0.519
2020 Hofseth LJ, Hebert JR, Chanda A, Chen H, Love BL, Pena MM, Murphy EA, Sajish M, Sheth A, Buckhaults PJ, Berger FG. Early-onset colorectal cancer: initial clues and current views. Nature Reviews. Gastroenterology & Hepatology. PMID 32086499 DOI: 10.1038/S41575-019-0253-4  0.33
2020 Makena MR, Dang D, Mekile A, Buckhaults P, Rao R. Abstract 5276: Secretory pathway calcium ATPase 2 (SPCA2) promotes cell survival and chemoresistance in receptor positive breast cancer cells Cancer Research. 80: 5276-5276. DOI: 10.1158/1538-7445.Am2020-5276  0.498
2019 Dwyer AJ, Murphy CC, Boland CR, Garcia R, Hampel H, Limburg P, Lowery J, Zauber AG, Waring S, Worrall S, Perea J, Siegel R, Lee J, Molmenti C, Sears CL, ... Buckhaults P, et al. A summary of the Fight Colorectal Cancer working meeting: exploring risk factors and etiology of sporadic early-age onset colorectal cancer. Gastroenterology. PMID 31095950 DOI: 10.1053/J.Gastro.2019.04.049  0.477
2019 Liu C, Banister CE, Buckhaults PJ. Spindle assembly checkpoint inhibition can resensitize p53-null stem cells to cancer chemotherapy. Cancer Research. PMID 30862715 DOI: 10.1158/0008-5472.Can-18-3024  0.589
2018 Ibrahim ML, Klement JD, Lu C, Redd PS, Xiao W, Yang D, Browning DD, Savage NM, Buckhaults PJ, Morse HC, Liu K. Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis. Cell Reports. 25: 3036-3046.e6. PMID 30540937 DOI: 10.1016/J.Celrep.2018.11.050  0.425
2018 Li Y, Buckhaults P, Li S, Tollefsbol TO. Temporal efficacy of a sulforaphane-based broccoli sprout diet in prevention of breast cancer through modulation of epigenetic mechanisms. Cancer Prevention Research (Philadelphia, Pa.). PMID 29764806 DOI: 10.1158/1940-6207.Capr-17-0423  0.453
2018 Liu C, Banister CE, Weige CC, Altomare D, Richardson JH, Contreras CM, Buckhaults PJ. PRDM1 silences stem cell-related genes and inhibits proliferation of human colon tumor organoids. Proceedings of the National Academy of Sciences of the United States of America. PMID 29760071 DOI: 10.1073/Pnas.1802902115  0.722
2017 Oliver D, Ji H, Liu P, Gasparian A, Gardiner E, Lee S, Zenteno A, Perinskaya LO, Chen M, Buckhaults P, Broude E, Wyatt MD, Valafar H, Peña E, Shtutman M. Identification of novel cancer therapeutic targets using a designed and pooled shRNA library screen. Scientific Reports. 7: 43023. PMID 28223711 DOI: 10.1038/Srep43023  0.599
2017 Guo H, Zhang B, Nairn AV, Nagy T, Moremen KW, Buckhaults P, Pierce M. O-GlcNAc expression levels epigenetically regulate colon cancer tumorigenesis by affecting the cancer stem cell compartment via modulating expression of transcriptional factor MYBL1. The Journal of Biological Chemistry. PMID 28096468 DOI: 10.1074/Jbc.M116.763201  0.408
2017 Banister CE, Liu C, Pirisi L, Creek KE, Buckhaults PJ. Identification and characterization of HPV-independent cervical cancers. Oncotarget. PMID 28077784 DOI: 10.18632/Oncotarget.14533  0.348
2017 Zhang X, Li Y, Akinyemiju T, Ojesina AI, Buckhaults P, Liu N, Xu B, Yi N. Pathway-Structured Predictive Model for Cancer Survival Prediction: A Two-Stage Approach. Genetics. 205: 89-100. PMID 28049703 DOI: 10.1534/Genetics.116.189191  0.41
2017 Weige CC, Anderson EL, Richardson J, Contreras C, Buckhaults PJ. Abstract B10: Synthetic lethal screen to identify novel therapies targeting TP53-mutant colon cancer cells Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-B10  0.739
2017 Banister CE, Pirisi L, Creek KE, Buckhaults PJ. Abstract B01: Integrated genomic analysis identifies two subsets of cervical cancer with potentially distinct therapeutic profiles Clinical Cancer Research. 23. DOI: 10.1158/1557-3265.Pmccavuln16-B01  0.427
2017 Weige CC, Liu C, Anderson EL, Banister CE, Richardson J, Contreras C, Buckhaults PJ. Abstract B14: TP53 synthetic lethal targets in colon cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Crc16-B14  0.744
2016 Beasley S, Buckhaults PJ, Pedigo NG, Farrell CL. Association of FGD1 polymorphisms with early-onset breast cancer. Oncology Letters. 12: 2071-2077. PMID 27602141 DOI: 10.3892/Ol.2016.4911  0.479
2016 Li Y, Buckhaults P, Cui X, Tollefsbol TO. Combinatorial epigenetic mechanisms and efficacy of early breast cancer inhibition by nutritive botanicals. Epigenomics. PMID 27478970 DOI: 10.2217/Epi-2016-0024  0.474
2016 Kho E, Livi CB, Buckhaults P, Carobbio F, Nam H, Kirkman R, Crossman D, Vayalil PK, Wei S, DeBerardinis RJ, Sudarshan S. Abstract 53: Epigenetic silencing of krebs cycle metabolism in kidney cancer Cancer Research. 76: 53-53. DOI: 10.1158/1538-7445.Am2016-53  0.414
2014 Weige CC, Birtwistle MR, Mallick H, Yi N, Berrong Z, Cloessner E, Duff K, Tidwell J, Clendenning M, Wilkerson B, Farrell C, Bunz F, Ji H, Shtutman M, Creek KE, ... ... Buckhaults PJ, et al. Transcriptomes and shRNA suppressors in a TP53 allele-specific model of early-onset colon cancer in African Americans. Molecular Cancer Research : McR. 12: 1029-41. PMID 24743655 DOI: 10.1158/1541-7786.Mcr-13-0286-T  0.724
2013 Shull AY, Clendenning ML, Ghoshal-Gupta S, Farrell CL, Vangapandu HV, Dudas L, Wilkerson BJ, Buckhaults PJ. Somatic Mutations, Allele Loss, and DNA Methylation of the Cub and Sushi Multiple Domains 1 (CSMD1) Gene Reveals Association with Early Age of Diagnosis in Colorectal Cancer Patients Plos One. 8. PMID 23505554 DOI: 10.1371/Journal.Pone.0058731  0.443
2012 Shull AY, Latham-Schwark A, Ramasamy P, Leskoske K, Oroian D, Birtwistle MR, Buckhaults PJ. Novel somatic mutations to PI3K pathway genes in metastatic melanoma. Plos One. 7: e43369. PMID 22912864 DOI: 10.1371/Journal.Pone.0043369  0.317
2012 Xi C, Hu Y, Buckhaults P, Moskophidis D, Mivechi NF. Heat shock factor Hsf1 cooperates with ErbB2 (Her2/Neu) protein to promote mammary tumorigenesis and metastasis. The Journal of Biological Chemistry. 287: 35646-57. PMID 22847003 DOI: 10.1074/Jbc.M112.377481  0.446
2012 Jiao X, Wood LD, Lindman M, Jones S, Buckhaults P, Polyak K, Sukumar S, Carter H, Kim D, Karchin R, Sjöblom T. Somatic mutations in the Notch, NF-KB, PIK3CA, and Hedgehog pathways in human breast cancers. Genes, Chromosomes & Cancer. 51: 480-9. PMID 22302350 DOI: 10.1002/Gcc.21935  0.503
2012 Luo J, Choi J, Pei L, Awan F, Lee E, Liu J, Shull A, McCarthy BA, Wilson JM, Taylor KH, Wang X, Buckhaults PJ, Munn DH, Caldwell CW, Yan X, et al. Genome-Wide DNA Methylation Landscape Defines IGHV Mutated and Unmutated B Cell Chronic Lymphocytic Leukemias Blood. 120: 526-526. DOI: 10.1182/Blood.V120.21.526.526  0.372
2010 Wang TL, Davidson B, Buckhaults PJ, Huang CS, Poul G. Molecular genetic markers in female reproductive cancers. Journal of Oncology. 2010: 307460. PMID 21541207 DOI: 10.1155/2010/307460  0.426
2010 Lauring J, Cosgrove DP, Fontana S, Gustin JP, Konishi H, Abukhdeir AM, Garay JP, Mohseni M, Wang GM, Higgins MJ, Gorkin D, Reis M, Vogelstein B, Polyak K, Cowherd M, ... Buckhaults PJ, et al. Knock in of the AKT1 E17K mutation in human breast epithelial cells does not recapitulate oncogenic PIK3CA mutations Oncogene. 29: 2337-2345. PMID 20101210 DOI: 10.1038/Onc.2009.516  0.468
2009 Meeh PF, Farrell CL, Croshaw R, Crimm H, Miller SK, Oroian D, Kowli S, Zhu J, Carver W, Wu W, Pena E, Buckhaults PJ. A gene expression classifier of node-positive colorectal cancer. Neoplasia (New York, N.Y.). 11: 1074-83. PMID 19794966 DOI: 10.1593/Neo.09808  0.44
2009 Lin Y, Buckhaults PJ, Lee JR, Xiong H, Farrell C, Podolsky RH, Schade RR, Dynan WS. Association of the actin-binding protein transgelin with lymph node metastasis in human colorectal cancer. Neoplasia (New York, N.Y.). 11: 864-73. PMID 19724680 DOI: 10.1593/Neo.09542  0.41
2009 Cronin JC, Wunderlich J, Loftus SK, Prickett TD, Wei X, Ridd K, Vemula S, Burrell AS, Agrawal NS, Lin JC, Banister CE, Buckhaults P, Rosenberg SA, Bastian BC, Pavan WJ, et al. Frequent mutations in the MITF pathway in melanoma. Pigment Cell & Melanoma Research. 22: 435-44. PMID 19422606 DOI: 10.1111/J.1755-148X.2009.00578.X  0.367
2009 Palavalli LH, Prickett TD, Wunderlich JR, Wei X, Burrell AS, Porter-Gill P, Davis S, Wang C, Cronin JC, Agrawal NS, Lin JC, Westbroek W, Hoogstraten-Miller S, Molinolo AA, Fetsch P, ... ... Buckhaults P, et al. Analysis of the matrix metalloproteinase family reveals that MMP8 is often mutated in melanoma. Nature Genetics. 41: 518-20. PMID 19330028 DOI: 10.1038/Ng.340  0.316
2008 Farrell C, Crimm H, Meeh P, Croshaw R, Barbar T, Vandersteenhoven JJ, Butler W, Buckhaults P. Somatic mutations to CSMD1 in colorectal adenocarcinomas. Cancer Biology & Therapy. 7: 609-13. PMID 18614856 DOI: 10.4161/Cbt.7.4.5623  0.535
2007 Wood LD, Parsons DW, Jones S, Lin J, Sjöblom T, Leary RJ, Shen D, Boca SM, Barber T, Ptak J, Silliman N, Szabo S, Dezso Z, Ustyanksky V, Nikolskaya T, ... ... Buckhaults P, et al. The genomic landscapes of human breast and colorectal cancers. Science (New York, N.Y.). 318: 1108-13. PMID 17932254 DOI: 10.1126/science.1145720  0.462
2007 Lin Y, Meeh PF, Farrell C, Buckhaults P, Podolsky RH, Lee JR, Schade RR, Dynan WS. Quantitative Proteomic Profiling of Colorectal Cancer Stratified by Lymph Node and 8p LOH Status American Journal of Gastroenterology. 102: S256. DOI: 10.14309/00000434-200709002-00383  0.392
2007 Parmigiani G, Lin J, Boca SM, Sjöblom T, Jones S, Wood LD, Parsons DW, Barber T, Buckhaults P, Markowitz SD, Park BH, Bachman KE, Papadopoulos N, Vogelstein B, Kinzler KW, et al. Response to comments on "The consensus coding sequences of human breast and colorectal cancers" Science. 317: 1500d. DOI: 10.1126/Science.1138773  0.359
2006 Sjöblom T, Jones S, Wood LD, Parsons DW, Lin J, Barber TD, Mandelker D, Leary RJ, Ptak J, Silliman N, Szabo S, Buckhaults P, Farrell C, Meeh P, Markowitz SD, et al. The consensus coding sequences of human breast and colorectal cancers Science. 314: 268-274. PMID 16959974 DOI: 10.1126/science.1133427  0.475
2006 Buckhaults P. Gene expression determinants of clinical outcome. Current Opinion in Oncology. 18: 57-61. PMID 16357565 DOI: 10.1097/01.Cco.0000198022.76476.B2  0.368
2004 Nanda A, Buckhaults P, Seaman S, Agrawal N, Boutin P, Shankara S, Nacht M, Teicher B, Stampfl J, Singh S, Vogelstein B, Kinzler KW, St Croix B. Identification of a binding partner for the endothelial cell surface proteins TEM7 and TEM7R. Cancer Research. 64: 8507-11. PMID 15574754 DOI: 10.1158/0008-5472.Can-04-2716  0.336
2004 Koopmann J, Buckhaults P, Brown DA, Zahurak ML, Sato N, Fukushima N, Sokoll LJ, Chan DW, Yeo CJ, Hruban RH, Breit SN, Kinzler KW, Vogelstein B, Goggins M. Serum macrophage inhibitory cytokine 1 as a marker of pancreatic and other periampullary cancers. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 10: 2386-92. PMID 15073115 DOI: 10.1158/1078-0432.Ccr-03-0165  0.433
2001 Saha S, Bardelli A, Buckhaults P, Velculescu VE, Rago C, St Croix B, Romans KE, Choti MA, Lengauer C, Kinzler KW, Vogelstein B. A phosphatase associated with metastasis of colorectal cancer. Science (New York, N.Y.). 294: 1343-6. PMID 11598267 DOI: 10.1126/Science.1065817  0.577
1998 Zhou S, Buckhaults P, Zawel L, Bunz F, Riggins G, Dai JL, Kern SE, Kinzler KW, Vogelstein B. Targeted deletion of Smad4 shows it is required for transforming growth factor beta and activin signaling in colorectal cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 95: 2412-6. PMID 9482899 DOI: 10.1073/Pnas.95.5.2412  0.374
1997 Buckhaults P, Chen L, Fregien N, Pierce M. Transcriptional regulation of N-acetylglucosaminyltransferase V by the src oncogene. The Journal of Biological Chemistry. 272: 19575-81. PMID 9235963 DOI: 10.1074/Jbc.272.31.19575  0.316
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