James Spicer - Publications

Affiliations: 
Research Oncology King's College London, London, UK 

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Year Citation  Score
2023 Spicer J, Basu B, Montes A, Banerji U, Kristeleit R, Miller R, Veal GJ, Corrigan CJ, Till SJ, Figini M, Canevari S, Barton C, Jones P, Mellor S, Carroll S, et al. Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial. Nature Communications. 14: 4180. PMID 37491373 DOI: 10.1038/s41467-023-39679-9  0.307
2023 Ghorani E, Quartagno M, Blackhall F, Gilbert DC, O'Brien M, Ottensmeier C, Pizzo E, Spicer J, Williams A, Badman P, Parmar MKB, Seckl MJ. REFINE-Lung implements a novel multi-arm randomised trial design to address possible immunotherapy overtreatment. The Lancet. Oncology. 24: e219-e227. PMID 37142383 DOI: 10.1016/S1470-2045(23)00095-5  0.305
2022 Hughes DJ, Kapiris M, Podvez Nevajda A, McGrath H, Stavraka C, Ahmad S, Taylor B, Cook GJR, Ghosh S, Josephs D, Pintus E, Gennatas S, Bille A, Ryanna K, Santis G, ... ... Spicer J, et al. Non-Small Cell Lung Cancer (NSCLC) in Young Adults, Age < 50, Is Associated with Late Stage at Presentation and a Very Poor Prognosis in Patients That Do Not Have a Targeted Therapy Option: A Real-World Study. Cancers. 14. PMID 36551542 DOI: 10.3390/cancers14246056  0.348
2020 Russell B, Moss C, Papa S, Irshad S, Ross P, Spicer J, Kordasti S, Crawley D, Wylie H, Cahill F, Haire A, Zaki K, Rahman F, Sita-Lumsden A, Josephs D, et al. Factors Affecting COVID-19 Outcomes in Cancer Patients: A First Report From Guy's Cancer Center in London. Frontiers in Oncology. 10: 1279. PMID 32903324 DOI: 10.3389/Fonc.2020.01279  0.38
2020 Middleton G, Fletcher P, Popat S, Savage J, Summers Y, Greystoke A, Gilligan D, Cave J, O'Rourke N, Brewster A, Toy E, Spicer J, Jain P, Dangoor A, Mackean M, et al. Publisher Correction: The National Lung Matrix Trial of personalized therapy in lung cancer. Nature. PMID 32887973 DOI: 10.1038/S41586-020-2656-3  0.341
2020 Maringe C, Spicer J, Morris M, Purushotham A, Nolte E, Sullivan R, Rachet B, Aggarwal A. The impact of the COVID-19 pandemic on cancer deaths due to delays in diagnosis in England, UK: a national, population-based, modelling study. The Lancet. Oncology. PMID 32702310 DOI: 10.1016/S1470-2045(20)30388-0  0.31
2020 Middleton G, Fletcher P, Popat S, Savage J, Summers Y, Greystoke A, Gilligan D, Cave J, O'Rourke N, Brewster A, Toy E, Spicer J, Jain P, Dangoor A, Mackean M, et al. The National Lung Matrix Trial of personalized therapy in lung cancer. Nature. PMID 32669708 DOI: 10.1038/S41586-020-2481-8  0.415
2020 Torricelli F, Saxena A, Nuamah R, Neat M, Harling L, Ng W, Spicer J, Ciarrocchi A, Bille A. Genomic analysis in short- and long-term patients with malignant pleura mesothelioma treated with palliative chemotherapy. European Journal of Cancer (Oxford, England : 1990). 132: 104-111. PMID 32339978 DOI: 10.1016/J.Ejca.2020.03.002  0.354
2020 Spicer J, Basu B, Montes A, Banerji U, Kristeleit R, Veal GJ, Corrigan C, Till S, Nintos G, Brier T, Funingana IG, Ang JE, Zaki K, Griffin A, Barton C, et al. Abstract CT141: Phase 1 trial of MOv18, a first-in-class IgE antibody therapy for cancer Cancer Research. 80. DOI: 10.1158/1538-7445.Am2020-Ct141  0.428
2020 Powell-Tuck C, Crawley D, Karapanagiotou E, Montes A, Holden S, Dawson J, Josephs D, Spicer J, Ghosh S. Psychological experiences in patients with lung cancer taking targeted therapies Lung Cancer. 139. DOI: 10.1016/S0169-5002(20)30221-X  0.381
2019 Spicer J, Provencio M, Garrido Lopez P, Bosch-Barrera J, de Castro Carpeño FJ, Felip E, Trigo J, Viteri S, Coart E, Schmidt E, Christiansen AV, Zocca MB, Andersen MH, Ehrnrooth E, Paz-Ares L. An open-label, randomized, phase I/II trial of IO102 and pembrolizumab, or IO102, pembrolizumab and chemotherapy, as first-line treatment for patients with metastatic non-small cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 30: ii65-ii66. PMID 32131320 DOI: 10.1093/Annonc/Mdz063.078  0.435
2019 Macpherson IR, Spiliopoulou P, Rafii S, Saggese M, Baird RD, Garcia-Corbacho J, Italiano A, Bonneterre J, Campone M, Cresti N, Posner J, Takeda Y, Arimura A, Spicer J. A phase I/II study of epertinib plus trastuzumab with or without chemotherapy in patients with HER2-positive metastatic breast cancer. Breast Cancer Research : Bcr. 22: 1. PMID 31892325 DOI: 10.1186/S13058-019-1178-0  0.393
2019 Fenwick JD, Landau DB, Baker A, Bates AT, Eswar C, Garcia-Alonso A, Harden SV, Illsley MC, Laurence V, Malik Z, Mayles WPM, Miles E, Mohammed N, Spicer J, Wells P, et al. Long-term results from the IDEAL-CRT phase 1/2 trial of isotoxically dose-escalated radiation therapy and concurrent chemotherapy for stage II/III non-small cell lung cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 31809876 DOI: 10.1016/J.Ijrobp.2019.11.397  0.406
2019 Khan M, Spicer J. The Evolving Landscape of Cancer Therapeutics. Handbook of Experimental Pharmacology. PMID 31792681 DOI: 10.1007/164_2019_312  0.385
2019 Marabelle A, Baurain J, Awada A, Kristeleit RS, Loirat D, Jossang DE, Jebsen NL, Sveinbjornsson B, Rekdal Ø, Gjerstad VS, Brunsvig P, Galon J, Hermitte F, Patel H, Spicer J. Abstract CT069: A Phase I study of the oncolytic peptide LTX-315 generatesde novoT-cell responses and clinical benefit in patients with advanced melanoma Cancer Research. 79. DOI: 10.1158/1538-7445.Am2019-Ct069  0.415
2019 Hughes DJ, Chand G, Josephs D, Harries M, Papa S, Spicer J, Ting HH, Goh V, Cook G. 173TiP PECan Study, Imaging PD-L1 in Cancer: A Tool for Measuring Response to Immunotherapy? Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz450.010  0.303
2019 Dillon M, Guevara J, Mohammed K, Smith SA, Dean E, McLellan L, Boylan Z, Spicer J, Forster MD, Harrington KJ. A phase I study of ATR inhibitor, AZD6738, as monotherapy in advanced solid tumours (PATRIOT part A, B) Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz244.012  0.354
2019 Torricelli F, Saxena A, Nuamah R, Neat M, Harling L, Ng W, Spicer J, Ciarrocchi A, Bille A. MA12.05 Genomic Analysis of Long Term Malignant Pleura Mesothelioma Patients Treated with Palliative Chemotherapy Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.08.595  0.301
2019 Felip E, Brunsvig P, Helland Å, Viñolas N, Aix S, Carcereny E, Gomez MD, Perez JMT, Arriola E, Campelo RG, Spicer J, Thompson J, Granados ALO, Holt R, Smethurst D, et al. MA03.06 Efficacy Results of Selective AXL Inhibitor Bemcentinib with Pembrolizumab Following Chemotherapy in Patients with NSCLC Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.08.515  0.396
2019 Middleton G, Popat S, Fletcher P, Summers YJ, Greystoke A, Gilligan D, Cave J, O'Rourke N, Brewster A, Toy E, Spicer J, Savage J, Sharpe R, Yap T, Swanton C, et al. PL02.09 National Lung Matrix Trial (NLMT): First Results from an Umbrella Phase II Trial in Advanced Non-Small Cell Lung Cancer (NSCLC) Journal of Thoracic Oncology. 14. DOI: 10.1016/J.Jtho.2019.08.060  0.385
2018 Concin N, Vergote IB, Lassen UN, Drew Y, Machiels JP, Arkenau HT, Forster MD, Jones R, Johnson ML, Slomovitz BM, Spicer J, Cornez N, Gennigens C, Coleman RL, Windfeld K, et al. A phase IIa study of tisotumab vedotin in patients with previously treated recurrent or metastatic cervical cancer: Updated analysis of full cervical expansion cohort. Annals of Oncology : Official Journal of the European Society For Medical Oncology. 29: viii344. PMID 32136816 DOI: 10.1093/Annonc/Mdy285.170  0.356
2018 Harling L, Kolokotroni SM, Nair A, Smelt J, King J, Routledge T, Spicer J, Ng W, Bille A. Differential Survival characteristics of sarcomatoid subtype biphasic pleural mesothelioma. The Annals of Thoracic Surgery. PMID 30389446 DOI: 10.1016/J.Athoracsur.2018.09.019  0.318
2018 Plummer R, Verheul HM, De Vos FYFL, Leunen K, Molife LR, Rolfo C, Grundtvig-Sørensen P, De Grève J, Rottey S, Jerusalem G, Italiano A, Spicer J, Dirix L, Goessl C, Birkett J, et al. Pharmacokinetic Effects and Safety of Olaparib Administered with Endocrine Therapy: A Phase I Study in Patients with Advanced Solid Tumours. Advances in Therapy. PMID 30324586 DOI: 10.1007/S12325-018-0804-Z  0.388
2018 Arkenau HT, Italiano A, Mak G, Toulmonde M, Baird RD, Garcia-Corbacho J, Plummer R, Flynn M, Forster M, Wilson RH, Tosi D, Adenis A, Donaldson K, Posner J, Kawabata I, ... ... Spicer J, et al. An extended phase Ib study of epertinib, an orally active reversible dual EGFR/HER2 tyrosine kinase inhibitor, in patients with solid tumours. European Journal of Cancer (Oxford, England : 1990). 103: 17-23. PMID 30196106 DOI: 10.1016/J.Ejca.2018.07.134  0.386
2018 O'Brien MER, Sarker D, Bhosle J, Thillai K, Yap TA, Uttenreuther-Fischer M, Pemberton K, Jin X, Wiebe S, de Bono J, Spicer J. A phase I study to assess afatinib in combination with carboplatin or with carboplatin plus paclitaxel in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology. PMID 30088048 DOI: 10.1007/S00280-018-3661-1  0.367
2018 Basu B, Krebs MG, Sundar R, Wilson RH, Spicer J, Jones R, Brada M, Talbot DC, Steele N, Ingles Garces AH, Brugger W, Harrington EA, Evans J, Hall E, Tovey H, et al. Vistusertib (dual m-TORC1/2 inhibitor) in combination with paclitaxel in patients with high grade serous ovarian and squamous non-small cell lung cancer. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 30016392 DOI: 10.1093/Annonc/Mdy245  0.42
2018 Møller H, Coupland VH, Tataru D, Peake MD, Mellemgaard A, Round T, Baldwin DR, Callister MEJ, Jakobsen E, Vedsted P, Sullivan R, Spicer J. Geographical variations in the use of cancer treatments are associated with survival of lung cancer patients. Thorax. PMID 29511056 DOI: 10.1136/Thoraxjnl-2017-210710  0.412
2018 Tokaca N, Pouptsis A, Karapanagiotou E, Spicer J, Halkyard E, Blackhall F, Summers Y, Greystoke A, Bhosle J, Jones A, Newsom-Davis T, Nicolson M, O’Brien M, Yousaf N, Popat S. Retrospective analysis of outcomes in UK patients with advanced NSCLC and ROS1 rearrangement Lung Cancer. 115. DOI: 10.1016/S0169-5002(18)30130-2  0.35
2018 Popat S, Januszewski A, Hughes L, O'Brien M, Ahmad T, Lewanski C, Dernedde U, Jankowska P, Mulatero C, Shah R, Hicks J, Geldart T, Cominos M, Gray G, Spicer J, et al. P1.13-17 Multicentre Phase II Trial of First-Line Afatinib in Patients with Suspected/Confirmed EGFR Mutant NSCLC: ctDNA and Long-Term Efficacy Journal of Thoracic Oncology. 13. DOI: 10.1016/J.Jtho.2018.08.874  0.361
2018 Arce-Lara C, Arriola E, Brunsvig P, Carcereny E, Domine M, Dragnev K, Felip E, Campelo RG, Krebs M, Paz-Ares L, Aix SP, Spicer J, Trigo JM, Segarra NV, Holt R, et al. P2.04-27 Ph II Study of Oral Selective AXL Inhibitor Bemcentinib (BGB324) in Combination with Pembrolizumab in Patients with Advanced NSCLC Journal of Thoracic Oncology. 13. DOI: 10.1016/J.Jtho.2018.08.1251  0.333
2017 Temam S, Spicer J, Farzaneh F, Soria JC, Oppenheim D, McGurk M, Hollebecque A, Sarini J, Hussain K, Soehrman Brossard S, Manenti L, Evers S, Delmar P, Di Scala L, Mancao C, et al. An exploratory, open-label, randomized, multicenter study to investigate the pharmacodynamics of a glycoengineered antibody (imgatuzumab) and cetuximab in patients with operable head and neck squamous cell carcinoma. Annals of Oncology : Official Journal of the European Society For Medical Oncology. PMID 28950289 DOI: 10.1093/Annonc/Mdx489  0.391
2017 Ferry D, Billingham L, Jarrett H, Dunlop D, Woll PJ, Nicolson M, Shah R, Thompson J, Spicer J, Muthukumar D, Skailes G, Leonard P, Chetiyawardana AD, Wells P, Lewanski C, et al. Carboplatin versus two doses of cisplatin in combination with gemcitabine in the treatment of advanced non-small-cell lung cancer: Results from a British Thoracic Oncology Group randomised phase III trial. European Journal of Cancer (Oxford, England : 1990). 83: 302-312. PMID 28780466 DOI: 10.1016/J.Ejca.2017.05.037  0.466
2017 Beddowes E, Spicer J, Chan PY, Khadeir R, Corbacho JG, Repana D, Steele JP, Schmid P, Szyszko T, Cook G, Diaz M, Feng X, Johnston A, Thomson J, Sheaff M, et al. Phase 1 Dose-Escalation Study of Pegylated Arginine Deiminase, Cisplatin, and Pemetrexed in Patients With Argininosuccinate Synthetase 1-Deficient Thoracic Cancers. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016713230. PMID 28388291 DOI: 10.1200/Jco.2016.71.3230  0.397
2017 Wilson RH, Evans TJ, Middleton MR, Molife LR, Spicer J, Dieras V, Roxburgh P, Giordano H, Jaw-Tsai S, Goble S, Plummer R. A phase I study of intravenous and oral rucaparib in combination with chemotherapy in patients with advanced solid tumours. British Journal of Cancer. PMID 28222073 DOI: 10.1038/Bjc.2017.36  0.401
2017 Rafii S, Macpherson I, Baird R, Saggese M, Spiliopoulou P, Kumar S, Italiano A, Bonneterre J, Campone M, Cresti N, Posner J, Takeda Y, Arimura A, Spicer J. Abstract P4-21-08: A phase I/II of S-222611, a reversible EGFR and HER2 inhibitor, combined with trastuzumab +/- chemotherapy in patients with HER2-positive metastatic breast cancer Cancer Research. 77. DOI: 10.1158/1538-7445.Sabcs16-P4-21-08  0.393
2017 Papa S, Adami A, Metoudi M, Achkova D, Schalkwyk Mv, Pereira AP, Bosshard-Carter L, Whilding L, Stegen Svd, Davies DM, Guerrero-Urbano T, Jeannon JP, Spicer J, Maher J. Abstract CT118: T4 immunotherapy of head and neck squamous cell carcinoma using pan-ErbB targeted CAR T-cells Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Ct118  0.315
2017 Baurain J, Awada A, Brunsvig PF, Kristeleit R, Loirat D, Jøssang DE, Zitvogel L, Kroemer G, Marabelle A, Rekdal Ø, Sveinbjørnsson B, Wold H, Nicolaisen B, Saunders A, Spicer J. Abstract CT108: A phase I dose escalation study of intra-tumoral LTX-315 as monotherapy or in combination with either ipilimumab or pembrolizumab in patients with transdermally accessible tumors (NCT01986426) Cancer Research. 77. DOI: 10.1158/1538-7445.Am2017-Ct108  0.376
2017 Vergote I, Dean EJ, Lassen U, Bono JD, Drew Y, Machiels J, Nielsen D, Arkenau H, Forster M, Jones R, Slomovitz B, Spicer J, Johnson M, Cornez N, Gennigens C, et al. 9310 A phase IIa study of tisotumab vedotin (HuMax (R)-TF-ADC) in patients with relapsed, recurrent and/or metastatic cervical cancer. Annals of Oncology. 28. DOI: 10.1093/Annonc/Mdx372.001  0.358
2017 Hunter S, Nickless G, Ghosh S, Lal R, Merrick SA, Montes A, Smith D, Spicer J, Karapanagiotou E. 72: Treatment outcomes with tyrosine kinase inhibitors in patients with uncommon EGFR mutations in non-small cell lung cancer Lung Cancer. 103. DOI: 10.1016/S0169-5002(17)30122-8  0.398
2017 Tokaca N, Crawford MS, Greystoke A, Appel W, Lal R, Steele N, Ali C, Bezecny P, Fernando S, Karapanagiotou E, Skailes G, Dorey N, Harrow S, Bhosle J, Khan O, ... ... Spicer J, et al. 69: Outcomes with nintedanib and docetaxel in patients with relapsed NSCLC adenocarcinoma treated within the UK Nintedanib Individual Patient Supply programme Lung Cancer. 103. DOI: 10.1016/S0169-5002(17)30119-8  0.365
2017 Kindler HL, Novello S, Fennell D, Blumenschein G, Bearz A, Ceresoli G, Aerts J, Spicer J, Taylor P, Greystoke A, Nackaerts K, Calabro L, Burgers S, Jennens R, Sporchia A, et al. OA 02.01 Randomized Phase II Study of Anetumab Ravtansine or Vinorelbine in Patients with Metastatic Pleural Mesothelioma Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2017.09.328  0.33
2017 Bille A, Kolokotroni SM, King J, Smelt J, Ashrafian L, Spicer J, Routledge T, Ng W. P3.03-037 Impact of Sarcomatoid Component in Patients with Biphasic Mesothelioma: Review of 118 Patients: Topic: Mesothelioma Clinical Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2016.11.1936  0.313
2017 Krebs M, Spicer J, Steele N, Talbot D, Brada M, Wilson R, Jones R, Basu B, Dawes J, Parmar M, Purchase B, Turner A, Hall E, Tovey H, Banerji U, et al. P3.02c-003 TAX-TORC: The novel combination of weekly paclitaxel and the dual mTORC1/2 inhibitor AZD2014 for the treatment of squamous NSCLC. Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2016.11.1798  0.317
2017 Popat S, Hughes L, O'Brien M, Ahmad T, Lewanski C, Dernedde U, Jankowska P, Mulatero C, Shah R, Hicks J, Geldart T, Cominos M, Gray G, Spicer J, Bell K, et al. P3.02b-046 Afatinib Benefits Patients with Confirmed/Suspected EGFR Mutant NSCLC, Unsuitable for Chemotherapy (TIMELY Phase II Trial): Topic: EGFR Clinical Journal of Thoracic Oncology. 12. DOI: 10.1016/J.Jtho.2016.11.1713  0.385
2016 Jensen-Jarolim E, Bax HJ, Bianchini R, Capron M, Corrigan C, Castells M, Dombrowicz D, Daniels-Wells TR, Fazekas J, Fiebiger E, Gatault S, Gould HJ, Janda J, Josephs DH, Karagiannis P, ... ... Spicer JF, et al. AllergoOncology - The impact of Allergy in Oncology. EAACI Position Paper. Allergy. PMID 28032353 DOI: 10.1111/All.13119  0.324
2016 Lee SM, Falzon M, Blackhall F, Spicer J, Nicolson M, Chaudhuri A, Middleton G, Ahmed S, Hicks J, Crosse B, Napier M, Singer JM, Ferry D, Lewanski C, Forster M, et al. Randomized Prospective Biomarker Trial of ERCC1 for Comparing Platinum and Nonplatinum Therapy in Advanced Non-Small-Cell Lung Cancer: ERCC1 Trial (ET). Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. JCO2016681841. PMID 27893326 DOI: 10.1200/Jco.2016.68.1841  0.432
2016 Spicer J, Irshad S, Ang JE, Enting D, Kristeleit R, Uttenreuther-Fischer M, Pemberton K, Pelling K, Schnell D, de Bono J. A phase I study of afatinib combined with paclitaxel and bevacizumab in patients with advanced solid tumors. Cancer Chemotherapy and Pharmacology. PMID 27872953 DOI: 10.1007/S00280-016-3189-1  0.345
2016 Szlosarek PW, Steele JP, Nolan L, Gilligan D, Taylor P, Spicer J, Lind M, Mitra S, Shamash J, Phillips MM, Luong P, Payne S, Hillman P, Ellis S, Szyszko T, et al. Arginine Deprivation With Pegylated Arginine Deiminase in Patients With Argininosuccinate Synthetase 1-Deficient Malignant Pleural Mesothelioma: A Randomized Clinical Trial. Jama Oncology. PMID 27584578 DOI: 10.1001/Jamaoncol.2016.3049  0.403
2016 Landau DB, Hughes L, Baker A, Bates AT, Bayne MC, Counsell N, Garcia-Alonso A, Harden SV, Hicks JD, Hughes SR, Illsley MC, Khan I, Laurence V, Malik Z, Mayles H, ... ... Spicer J, et al. IDEAL-CRT: A Phase 1/2 Trial of Isotoxic Dose-Escalated Radiation Therapy and Concurrent Chemotherapy in Patients With Stage II/III Non-Small Cell Lung Cancer. International Journal of Radiation Oncology, Biology, Physics. PMID 27296040 DOI: 10.1016/J.Ijrobp.2016.03.031  0.433
2016 Thayaparan T, Stegen SJCvd, Puri ACPP, Petrovic RM, Spicer J, Maher J. Abstract A075: Immunotherapy of malignant pleural mesothelioma using cMET specific T-cells Cancer Immunology Research. 4. DOI: 10.1158/2326-6074.Cricimteatiaacr15-A075  0.351
2016 Baird R, Arkenau H, Deva S, Cresti N, Garcia-Corbacho J, Hogarth L, Frenkel E, Kawaguchi K, Arimura A, Donaldson K, Posner J, Sarker D, Jodrell D, Plummer R, Spicer J, et al. Abstract P4-14-26: Phase I expansion of S-222611, a reversible inhibitor of EGFR and HER2, in advanced solid tumors, including HER2-positive breast cancer patients with brain metastases Cancer Research. 76. DOI: 10.1158/1538-7445.Sabcs15-P4-14-26  0.441
2016 Rush H, Roca J, Dalby M, Smith D, Lal R, Spicer J, Montes A, Karapanagiotou E. 77 Systemic therapy is safe and effective in octogenarians with advanced lung cancer Lung Cancer. 91. DOI: 10.1016/S0169-5002(16)30094-0  0.36
2015 Wu Y, Spicer J. Nedaplatin: a new platinum for squamous lung cancer? The Lancet. Oncology. PMID 26522336 DOI: 10.1016/S1470-2045(15)00400-3  0.358
2015 Suder A, Ang JE, Kyle F, Harris D, Rudman S, Kristeleit R, Solca F, Uttenreuther-Fischer M, Pemberton K, Pelling K, Schnell D, de Bono J, Spicer J. A phase I study of daily afatinib, an irreversible ErbB family blocker, in combination with weekly paclitaxel in patients with advanced solid tumours. European Journal of Cancer (Oxford, England : 1990). 51: 2275-84. PMID 26296295 DOI: 10.1016/J.Ejca.2015.07.041  0.407
2015 Plummer R, Swaisland H, Leunen K, van Herpen CM, Jerusalem G, De Grève J, Lolkema MP, Soetekouw P, Mau-Sørensen M, Nielsen D, Spicer J, Fielding A, So K, Bannister W, Molife LR. Olaparib tablet formulation: effect of food on the pharmacokinetics after oral dosing in patients with advanced solid tumours. Cancer Chemotherapy and Pharmacology. PMID 26242220 DOI: 10.1007/S00280-015-2836-2  0.364
2015 Ramalingam S, Goss G, Rosell R, Schmid-Bindert G, Zaric B, Andric Z, Bondarenko I, Komov D, Ceric T, Khuri F, Samarzija M, Felip E, Ciuleanu T, Hirsh V, Wehler T, ... Spicer J, et al. A randomized phase II study of ganetespib, a heat shock protein 90 inhibitor, in combination with docetaxel in second-line therapy of advanced non-small cell lung cancer (GALAXY-1). Annals of Oncology : Official Journal of the European Society For Medical Oncology / Esmo. 26: 1741-8. PMID 25997818 DOI: 10.1093/Annonc/Mdv220  0.453
2015 Lang-Lazdunski L, Bille A, Papa S, Marshall S, Lal R, Galeone C, Landau D, Steele J, Spicer J. Pleurectomy/decortication, hyperthermic pleural lavage with povidone-iodine, prophylactic radiotherapy, and systemic chemotherapy in patients with malignant pleural mesothelioma: a 10-year experience. The Journal of Thoracic and Cardiovascular Surgery. 149: 558-65; discussion 5. PMID 25726878 DOI: 10.1016/J.Jtcvs.2014.10.041  0.368
2015 Gao F, Pfeifer E, Farah H, Karampini E, Dua D, Kamal N, Cane P, Tobal K, Sethi T, Spicer J, McCaughan F. Microdroplet digital PCR: detection and quantitation of biomarkers in archived tissue and serial plasma samples in patients with lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 10: 212-7. PMID 25654729 DOI: 10.1097/Jto.0000000000000349  0.38
2015 Shapiro GI, Bell-McGuinn KM, Molina JR, Bendell J, Spicer J, Kwak EL, Pandya SS, Millham R, Borzillo G, Pierce KJ, Han L, Houk BE, Gallo JD, Alsina M, Braña I, et al. First-in-Human Study of PF-05212384 (PKI-587), a Small-Molecule, Intravenous, Dual Inhibitor of PI3K and mTOR in Patients with Advanced Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1888-95. PMID 25652454 DOI: 10.1158/1078-0432.Ccr-14-1306  0.427
2015 Spicer J, Baird R, Suder A, Cresti N, Corbacho JG, Hogarth L, Frenkel E, Matsumoto S, Kawabata I, Donaldson K, Posner J, Sarker D, Jodrell D, Plummer R. Phase 1 dose-escalation study of S-222611, an oral reversible dual tyrosine kinase inhibitor of EGFR and HER2, in patients with solid tumours. European Journal of Cancer (Oxford, England : 1990). 51: 137-45. PMID 25434923 DOI: 10.1016/J.Ejca.2014.11.003  0.395
2015 Roulstone V, Khan K, Pandha HS, Rudman S, Coffey M, Gill GM, Melcher AA, Vile R, Harrington KJ, de Bono J, Spicer J. Phase I trial of cyclophosphamide as an immune modulator for optimizing oncolytic reovirus delivery to solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 21: 1305-12. PMID 25424857 DOI: 10.1158/1078-0432.Ccr-14-1770  0.31
2015 Karampini E, Farah H, Kamal N, Cane P, Moorhead J, Pomplun S, King J, Sethi T, Spicer J, McCaughan F. Circulating biomarkers and tumour molecular profiling in patients with non-small cell lung cancer European Respiratory Journal. DOI: 10.1183/13993003.Congress-2015.Pa525  0.41
2015 Spicer J, Tischer B, Peters M. P176 Epidermal Growth Factor Receptor (EGFR) Mutation Testing and Treatment Choice in Advanced Non-small Cell Lung Cancer (NSCLC): UK Findings from a Global Survey Thorax. 70. DOI: 10.1136/Thoraxjnl-2015-207770.313  0.372
2015 Karampini E, Muhith A, Farah H, King J, Cane P, Spicer J, McCaughan F. S105 Microdroplet digital PCR for the longitudinal monitoring of circulating tumour DNA biomarkers in unselected patients with advanced lung cancer Thorax. 70. DOI: 10.1136/Thoraxjnl-2015-207770.111  0.381
2015 Charlton P, Josephides E, Karapanagiotou E, Montes A, Spicer J, Lal R. 131Pduration And Tolerance Of Maintenance Pemetrexed (Mpem) Treatment For Advanced Non-Small Cell Lung Cancer Annals of Oncology. 26. DOI: 10.1093/Annonc/Mdv050.35  0.397
2015 Charlton P, Karapanagiotou E, Montes A, Spicer J, Lal R. 60: Discontinuation of maintenance pemetrexed (mPEM) in non-small cell lung cancer (NSCLC) due to renal failure Lung Cancer. 87. DOI: 10.1016/S0169-5002(15)50060-3  0.346
2015 Lang-Lazdunski L, Bille A, Lal R, Landau D, Spicer J. 56: Pleurectomy/decortication, hyperthermic pleural lavage with povidone-iodine, prophylactic radiotherapy and systemic chemotherapy in malignant pleural mesothelioma. Experience in 100 consecutive patients Lung Cancer. 87. DOI: 10.1016/S0169-5002(15)50056-1  0.336
2015 Karampini E, Farah H, Mills G, Kamal N, Tobal K, Cane P, Muirhead J, Pomplun S, King JE, Sethi T, McCaughan F, Spicer J. 8: Tumour molecular profiling and quantitative detection of circulating biomarkers in patients with lung cancer Lung Cancer. 87. DOI: 10.1016/S0169-5002(15)50008-1  0.388
2014 Lee S, Blackhall FH, Spicer J, Nicolson MC, Chaudhuri A, Middleton G, Ahmed S, Hicks J, Crosse B, Napier M, Singer J, Ferry D, Lewanski C, Rolls S, Iles N, et al. 169OET: A RANDOMIZED, MULTICENTER, PHASE III TRIAL OF PLATINUM VERSUS NONPLATINUM CHEMOTHERAPY, AFTER ERCC1 STRATIFICATION, IN PATIENTS WITH ADVANCED/METASTATIC NON-SMALL CELL LUNG CANCER (NSCLC). Annals of Oncology : Official Journal of the European Society For Medical Oncology. 25: iv59. PMID 28170639 DOI: 10.1093/Annonc/Mdu326.3  0.373
2014 Blagden S, Omlin A, Olmin A, Josephs D, Stavraka C, Zivi A, Pinato DJ, Anthoney A, Decordova S, Swales K, Riisnaes R, Pope L, Noguchi K, Shiokawa R, Inatani M, ... ... Spicer J, et al. First-in-human study of CH5132799, an oral class I PI3K inhibitor, studying toxicity, pharmacokinetics, and pharmacodynamics, in patients with metastatic cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 20: 5908-17. PMID 25231405 DOI: 10.1158/1078-0432.Ccr-14-1315  0.377
2014 Camidge DR, Berge EM, Doebele RC, Ballas MS, Jahan T, Haigentz M, Hoffman D, Spicer J, West H, Lee P, Yang L, Joshi A, Gao L, Yurasov S, Mita A. A phase II, open-label study of ramucirumab in combination with paclitaxel and carboplatin as first-line therapy in patients with stage IIIB/IV non-small-cell lung cancer. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 9: 1532-9. PMID 25170639 DOI: 10.1097/Jto.0000000000000273  0.448
2014 Sharrocks K, Spicer J, Camidge DR, Papa S. The impact of socioeconomic status on access to cancer clinical trials. British Journal of Cancer. 111: 1684-7. PMID 25093493 DOI: 10.1038/Bjc.2014.108  0.401
2014 Michalarea V, Calcasola M, Cane P, Tobal K, Izatt L, Spicer J. EGFR-mutated lung cancer in Li-Fraumeni syndrome. Lung Cancer (Amsterdam, Netherlands). 85: 485-7. PMID 25047674 DOI: 10.1016/J.Lungcan.2014.06.017  0.362
2014 Corrigan A, Walker JL, Wickramasinghe S, Hernandez MA, Newhouse SJ, Folarin AA, Lewis CM, Sanderson JD, Spicer J, Marinaki AM. Pharmacogenetics of pemetrexed combination therapy in lung cancer: pathway analysis reveals novel toxicity associations. The Pharmacogenomics Journal. 14: 411-7. PMID 24732178 DOI: 10.1038/Tpj.2014.13  0.375
2014 Lüchtenborg M, Riaz SP, Lim E, Page R, Baldwin DR, Jakobsen E, Vedsted P, Lind M, Peake MD, Mellemgaard A, Spicer J, Lang-Lazdunski L, Møller H. Survival of patients with small cell lung cancer undergoing lung resection in England, 1998-2009. Thorax. 69: 269-73. PMID 24172710 DOI: 10.1136/Thoraxjnl-2013-203884  0.398
2014 Fennell D, Antonov A, Martins ML, Popat S, Ramalingam SS, Spicer J, Vukovic VM, El-Hariry I, Reichert V, Rosell R. Abstract 4657: Evaluation of genomic profiling in the GALAXY-1 (NCT01348126), a randomized Phase 2b study of ganetespib in combination with docetaxel versus docetaxel alone as second line therapy in patients with advanced NSCLC Cancer Research. 74: 4657-4657. DOI: 10.1158/1538-7445.Am2014-4657  0.402
2014 Thayaparan T, Stegen Svd, Pereira ACP, Petrovic R, Spicer J, Maher J. Abstract 2800: Immunotherapy of malignant pleural mesothelioma using MET specific t – cells Cancer Research. 74: 2800-2800. DOI: 10.1158/1538-7445.Am2014-2800  0.352
2014 Lüchtenborg M, Riaz SP, Lim E, Page R, Baldwin DR, Jakobsen E, Vedsted P, Lind MJ, Peake MD, Mellemgaard A, Spicer J, Lang-Lazdunski L, Møller H. 187 Survival of small cell lung cancer patients undergoing lung resection in England 1998-2009 Lung Cancer. 83. DOI: 10.1016/S0169-5002(14)70188-6  0.317
2014 Thillai K, Donovan V, Soultati A, Kandasamy R, Schalkwyk MV, Mather R, Najaryan N, Spicer J, Montes A, Lal R, Benepal T. 68 The prevalence of hyponatraemia amongst patients with newly diagnosed thoracic malignancies Lung Cancer. 83. DOI: 10.1016/S0169-5002(14)70068-6  0.391
2014 Thillai K, Soultati A, Lawrence H, Spicer J, Lal R, Montes A. 55 Lung cancer presenting with symptomatic bone metastases: Are we doing enough? Lung Cancer. 83. DOI: 10.1016/S0169-5002(14)70055-8  0.324
2014 Thillai K, Soultati A, Montes A, Karapanagiotou E, Spicer J, Lal R. 25 A retrospective analysis of patients with advanced EGFR mutated lung cancer treated with either first line erlotinib or gefitinib Lung Cancer. 83. DOI: 10.1016/S0169-5002(14)70026-1  0.41
2014 Dua D, Montes A, Warner M, Spicer J, Lal R. 24 Outcome in metastatic NSCLC without EGFR and KRAS mutation treated with second line erlotinib Lung Cancer. 83. DOI: 10.1016/S0169-5002(14)70025-X  0.316
2014 Beddowes EJ, Hatipoglu E, Montes A, Spicer J, Moller H, Lal R. 16 Characterising the use and impact of bisphosphonates in patients with bone metastases from non-small cell lung cancer; a single centre experience Lung Cancer. 83. DOI: 10.1016/S0169-5002(14)70017-0  0.373
2014 Gao F, Dua D, Pfeifer E, Farah H, Tobal K, Cane P, Spicer J, McCaughan F. 6 Microdroplet digital PCR in detecting mutational events in cell-free DNA in patients with lung cancer – a pilot study Lung Cancer. 83. DOI: 10.1016/S0169-5002(14)70007-8  0.368
2014 Papa S, Emami-Shahri N, Liu Z, Petrausch U, Mullen G, Spicer J, Maher J. Development of PSMA-specific immunotherapy for prostate cancer with PIN4 gene-modified T cells The Lancet. 383: S77. DOI: 10.1016/S0140-6736(14)60340-8  0.32
2013 Molife LR, Rudman SM, Alam S, Tan DS, Kristeleit H, Middleton G, Propper D, Bent L, Stopfer P, Uttenreuther-Fischer M, Wallenstein G, de Bono J, Spicer J. Phase II, open-label trial to assess QTcF effects, pharmacokinetics and antitumor activity of afatinib in patients with relapsed or refractory solid tumors. Cancer Chemotherapy and Pharmacology. 72: 1213-22. PMID 24085260 DOI: 10.1007/S00280-013-2286-7  0.383
2013 Spicer J, Moller H, Papa S. Reply to A. Surbone et al. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 2833. PMID 24058929 DOI: 10.1200/Jco.2013.49.6687  0.317
2013 Josephs DH, Fisher DS, Spicer J, Flanagan RJ. Clinical pharmacokinetics of tyrosine kinase inhibitors: implications for therapeutic drug monitoring. Therapeutic Drug Monitoring. 35: 562-87. PMID 24052062 DOI: 10.1097/Ftd.0B013E318292B931  0.339
2013 Bille A, Chicklore S, Okiror L, Cook GJ, Spicer J, Landau D, Lang-Lazdunski L. Patterns of disease progression on 18F-fluorodeoxyglucose positron emission tomography-computed tomography in patients with malignant pleural mesothelioma undergoing multimodality therapy with pleurectomy/decortication. Nuclear Medicine Communications. 34: 1075-83. PMID 23963351 DOI: 10.1097/Mnm.0B013E3283653862  0.309
2013 Papa S, Popat S, Shah R, Prevost AT, Lal R, McLennan B, Cane P, Lang-Lazdunski L, Viney Z, Dunn JT, Barrington S, Landau D, Spicer J. Phase 2 study of sorafenib in malignant mesothelioma previously treated with platinum-containing chemotherapy. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 8: 783-7. PMID 23571475 DOI: 10.1097/Jto.0B013E31828C2B26  0.405
2013 Simon ST, Higginson IJ, Benalia H, Gysels M, Murtagh FE, Spicer J, Bausewein C. Episodes of breathlessness: types and patterns - a qualitative study exploring experiences of patients with advanced diseases. Palliative Medicine. 27: 524-32. PMID 23486931 DOI: 10.1177/0269216313480255  0.304
2013 Yap TA, Arkenau HT, Camidge DR, George S, Serkova NJ, Gwyther SJ, Spratlin JL, Lal R, Spicer J, Desouza NM, Leach MO, Chick J, Poondru S, Boinpally R, Gedrich R, et al. First-in-human phase I trial of two schedules of OSI-930, a novel multikinase inhibitor, incorporating translational proof-of-mechanism studies. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 19: 909-19. PMID 23403628 DOI: 10.1158/1078-0432.Ccr-12-2258  0.368
2013 Lassen U, Miller WH, Hotte S, Evans TR, Kollmansberger C, Adamson D, Nielsen DL, Spicer J, Chen E, Meyer T, Brown K, Rafi R, Sawyer MB. Phase I evaluation of the effects of ketoconazole and rifampicin on cediranib pharmacokinetics in patients with solid tumours. Cancer Chemotherapy and Pharmacology. 71: 543-9. PMID 23196640 DOI: 10.1007/S00280-012-2038-0  0.344
2013 Shapiro G, Kristeleit R, Middleton M, Burris H, Molife LR, Evans J, Wilson R, LoRusso P, Spicer J, Dieras V, Patel M, Dominy E, Simpson D, Giordano H, Allen AR, et al. Abstract A218: Pharmacokinetics of orally administered rucaparib in patients with advanced solid tumors. Molecular Cancer Therapeutics. 12. DOI: 10.1158/1535-7163.Targ-13-A218  0.373
2013 Baird R, Cresti N, Beddowes E, Saggese M, Flynn M, Corbacho JG, Gao F, Lemech C, Donaldson K, Posner J, Kawabata I, Forster M, Arkenau H, Plummer R, Jodrell D, ... Spicer J, et al. Abstract P4-12-24: Phase I trial of S-222611, a dual tyrosine kinase inhibitor of EGFR and HER2, with preliminary evidence of efficacy in patients (pts) with heavily-pretreated HER2-positive metastatic breast cancer Cancer Research. 73. DOI: 10.1158/0008-5472.Sabcs13-P4-12-24  0.396
2013 Compton S, Michalarea V, Pintus E, Thomas R, Colvin M, Tindale-Paul P, Eestila S, Montes A, Spicer J, Lal R. 129 Treating non small cell lung cancer with erlotinib: the Nurse Led clinic experience Lung Cancer. 79. DOI: 10.1016/S0169-5002(13)70129-6  0.346
2013 Corrigan A, Lal R, Wickramasinghe S, Whelan S, Sanderson J, Marinaki A, Spicer J. 31 Testing for association between TPMT, COMT and NOX3 variants and the onset of ototoxicity in lung cancer patients treated with platinum chemotherapy Lung Cancer. 79. DOI: 10.1016/S0169-5002(13)70031-X  0.411
2013 Moss C, Cane P, Mclean E, Santis G, Tobal K, Spicer J. 13 Acquired resistance to EGFR inhibition: evolution from adenocarcinoma to small cell lung cancer (SCLC) Lung Cancer. 79. DOI: 10.1016/S0169-5002(13)70013-8  0.374
2012 Enting D, Spicer J. EGFR inhibition and more: a new generation growing up. Journal of Thoracic Disease. 4: 553-5. PMID 23205276 DOI: 10.3978/J.Issn.2072-1439.2012.10.04  0.362
2012 Pennycuick A, Simpson T, Crawley D, Lal R, Santis G, Cane P, Tobal K, Spicer J. Routine EGFR and KRAS Mutation analysis using COLD-PCR in non-small cell lung cancer. International Journal of Clinical Practice. 66: 748-752. PMID 22805266 DOI: 10.1111/J.1742-1241.2012.02961.X  0.319
2012 Bille A, Belcher E, Raubenheimer H, Landau D, Cane P, Spicer J, Lang-Lazdunski L. Induction chemotherapy, extrapleural pneumonectomy, and adjuvant radiotherapy for malignant pleural mesothelioma: experience of Guy's and St Thomas' hospitals. General Thoracic and Cardiovascular Surgery. 60: 289-96. PMID 22453539 DOI: 10.1007/S11748-011-0915-9  0.342
2012 Lang-Lazdunski L, Bille A, Lal R, Cane P, McLean E, Landau D, Steele J, Spicer J. Pleurectomy/decortication is superior to extrapleural pneumonectomy in the multimodality management of patients with malignant pleural mesothelioma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 7: 737-43. PMID 22425923 DOI: 10.1097/Jto.0B013E31824Ab6C5  0.331
2012 Jamal-Hanjani M, Spicer J. Epidermal growth factor receptor tyrosine kinase inhibitors in the treatment of epidermal growth factor receptor-mutant non-small cell lung cancer metastatic to the brain. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 18: 938-44. PMID 22167408 DOI: 10.1158/1078-0432.Ccr-11-2529  0.375
2012 Riaz SP, Lüchtenborg M, Coupland VH, Spicer J, Peake MD, Møller H. Trends in incidence of small cell lung cancer and all lung cancer. Lung Cancer (Amsterdam, Netherlands). 75: 280-4. PMID 21893364 DOI: 10.1016/J.Lungcan.2011.08.004  0.358
2012 Karagiannis P, Gilbert AE, Dodev T, Josephs DH, Ali N, Dafou D, Ainali C, Koers A, Tsoka S, Kaye SB, Spicer J, Gould HJ, Beavil A, Nestle FO, Karagiannis SN. Abstract 2524: Antibodies of the IgG and IgE classes against the melanoma-associated antigen HMW-MAA: Investigating a new therapeutic approach Cancer Research. 72: 2524-2524. DOI: 10.1158/1538-7445.Am2012-2524  0.324
2012 Camidge DR, Doebele RC, Ballas M, Jahan T, Haigentz M, Hoffman D, Spicer J, West H, Yurasov S, Mita AC. Final Results of a Phase 2, Open-Label Study of Ramucirumab (IMC-1121B; RAM), an IGG1 MAB Targeting Vegfr-2, with Paclitaxel and Carboplatin as First-Line Therapy in Patients (PTS) with Stage IIIB/IV Non-Small Cell Lung Cancer (NSCLC) (NCT00735696) Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)33884-9  0.34
2012 Noor AM, Vizor S, McLennan B, Sarker D, Moller H, Spicer J, Papa S. The Impact of Patient Socio-Econonomic Status on Access to Early Phase Cancer Trials Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)33040-4  0.389
2012 Enting D, Ang J, O'Hanlon-Brown C, Kristeleit R, Uttenreuther-Fischer M, Pemberton K, Pelling K, Schnell D, Bono JD, Spicer J. A Phase I Study of Daily Afatinib, an Irreversible Erbb Family Blocker, Combined With Weekly Paclitaxel and 2-Weekly Bevacizumab in Patients with Advanced Solid Tumours Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)33023-4  0.342
2012 Ng CHM, Macpherson I, Rea D, Spicer J, Bowman A, Jones A, Dowsett M, Johnston SRD, Dobbs N, Bono JSd. Phase I/II Trial of Abiraterone Acetate (AA) in Estrogen Receptor (ERα) or Androgen Receptor (AR) Positive Metastatic Breast Cancer (MBC) Annals of Oncology. 23. DOI: 10.1016/S0923-7534(20)32964-1  0.392
2012 Ahilathirunayagam S, Kalsi T, Husain Y, Wittenbecher F, Zohree MA, Babic-illman A, Moss C, Spicer J, Montes A, Harari D, Lal R. Chemotherapy dose density in elderly lung cancer patients requires frequent modifications: A retrospective case series from January 2011 to July 2012 Journal of Geriatric Oncology. 3. DOI: 10.1016/J.Jgo.2012.10.064  0.407
2011 Santis G, Angell R, Nickless G, Quinn A, Herbert A, Cane P, Spicer J, Breen R, McLean E, Tobal K. Screening for EGFR and KRAS mutations in endobronchial ultrasound derived transbronchial needle aspirates in non-small cell lung cancer using COLD-PCR. Plos One. 6: e25191. PMID 21949883 DOI: 10.1371/Journal.Pone.0025191  0.362
2011 Lang-Lazdunski L, Bille A, Belcher E, Cane P, Landau D, Steele J, Taylor H, Spicer J. Pleurectomy/decortication, hyperthermic pleural lavage with povidone-iodine followed by adjuvant chemotherapy in patients with malignant pleural mesothelioma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 6: 1746-52. PMID 21876457 DOI: 10.1097/Jto.0B013E3182288Af9  0.384
2011 Treasure T, Lang-Lazdunski L, Waller D, Bliss JM, Tan C, Entwisle J, Snee M, O'Brien M, Thomas G, Senan S, O'Byrne K, Kilburn LS, Spicer J, Landau D, Edwards J, et al. Extra-pleural pneumonectomy versus no extra-pleural pneumonectomy for patients with malignant pleural mesothelioma: clinical outcomes of the Mesothelioma and Radical Surgery (MARS) randomised feasibility study. The Lancet. Oncology. 12: 763-72. PMID 21723781 DOI: 10.1016/S1470-2045(11)70149-8  0.37
2011 Rudman SM, Josephs DH, Cambrook H, Karagiannis P, Gilbert AE, Dodev T, Hunt J, Koers A, Montes A, Taams L, Canevari S, Figini M, Blower PJ, Beavil AJ, Nicodemus CF, ... ... Spicer JF, et al. Harnessing engineered antibodies of the IgE class to combat malignancy: initial assessment of FcÉ›RI-mediated basophil activation by a tumour-specific IgE antibody to evaluate the risk of type I hypersensitivity. Clinical and Experimental Allergy : Journal of the British Society For Allergy and Clinical Immunology. 41: 1400-13. PMID 21569129 DOI: 10.1111/J.1365-2222.2011.03770.X  0.361
2011 Gilbert AE, Karagiannis P, Dodev T, Koers A, Lacy K, Josephs DH, Takhar P, Geh JL, Healy C, Harries M, Acland KM, Rudman SM, Beavil RL, Blower PJ, Beavil AJ, ... ... Spicer J, et al. Monitoring the systemic human memory B cell compartment of melanoma patients for anti-tumor IgG antibodies. Plos One. 6: e19330. PMID 21559411 DOI: 10.1371/Journal.Pone.0019330  0.342
2011 Patel GS, Kiuchi T, Lawler K, Ofo E, Fruhwirth GO, Kelleher M, Shamil E, Zhang R, Selvin PR, Santis G, Spicer J, Woodman N, Gillett CE, Barber PR, Vojnovic B, et al. The challenges of integrating molecular imaging into the optimization of cancer therapy. Integrative Biology : Quantitative Biosciences From Nano to Macro. 3: 603-31. PMID 21541433 DOI: 10.1039/C0Ib00131G  0.327
2011 Belcher E, Hardwick T, Lal R, Marshall S, Spicer J, Lang-Lazdunski L. Induction chemotherapy, cytoreductive surgery and intraoperative hyperthermic pleural irrigation in patients with stage IVA thymoma. Interactive Cardiovascular and Thoracic Surgery. 12: 744-7. PMID 21172935 DOI: 10.1510/Icvts.2010.255307  0.311
2011 Mitchell CL, O'Connor JP, Roberts C, Watson Y, Jackson A, Cheung S, Evans J, Spicer J, Harris A, Kelly C, Rudman S, Middleton M, Fielding A, Tessier J, Young H, et al. A two-part phase II study of cediranib in patients with advanced solid tumours: the effect of food on single-dose pharmacokinetics and an evaluation of safety, efficacy and imaging pharmacodynamics. Cancer Chemotherapy and Pharmacology. 68: 631-41. PMID 21120480 DOI: 10.1007/S00280-010-1534-3  0.318
2011 Lang-Lazdunski L, Bille A, Belcher E, Landau D, Steele J, Taylor H, Spicer J. 51 Pleurectomy/decortication, hyperthermic pleural lavage with povidone-iodine and adjuvant chemotherapy in patients with malignant pleural mesothelioma. A 6-year experience Lung Cancer. 71. DOI: 10.1016/S0169-5002(11)70051-4  0.344
2010 Comins C, Spicer J, Protheroe A, Roulstone V, Twigger K, White CM, Vile R, Melcher A, Coffey MC, Mettinger KL, Nuovo G, Cohn DE, Phelps M, Harrington KJ, Pandha HS. REO-10: a phase I study of intravenous reovirus and docetaxel in patients with advanced cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 16: 5564-72. PMID 20926400 DOI: 10.1158/1078-0432.Ccr-10-1233  0.42
2010 Yap TA, Vidal L, Adam J, Stephens P, Spicer J, Shaw H, Ang J, Temple G, Bell S, Shahidi M, Uttenreuther-Fischer M, Stopfer P, Futreal A, Calvert H, de Bono JS, et al. Phase I trial of the irreversible EGFR and HER2 kinase inhibitor BIBW 2992 in patients with advanced solid tumors. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 28: 3965-72. PMID 20679611 DOI: 10.1200/Jco.2009.26.7278  0.394
2010 Molife LR, Fong PC, Paccagnella L, Reid AH, Shaw HM, Vidal L, Arkenau HT, Karavasilis V, Yap TA, Olmos D, Spicer J, Postel-Vinay S, Yin D, Lipton A, Demers L, et al. The insulin-like growth factor-I receptor inhibitor figitumumab (CP-751,871) in combination with docetaxel in patients with advanced solid tumours: results of a phase Ib dose-escalation, open-label study. British Journal of Cancer. 103: 332-9. PMID 20628389 DOI: 10.1038/Sj.Bjc.6605767  0.389
2010 Spicer JF, Rudman SM. EGFR inhibitors in non-small cell lung cancer (NSCLC): the emerging role of the dual irreversible EGFR/HER2 inhibitor BIBW 2992. Targeted Oncology. 5: 245-55. PMID 20574858 DOI: 10.1007/s11523-010-0140-y  0.313
2010 Holmberg L, Sandin F, Bray F, Richards M, Spicer J, Lambe M, Klint A, Peake M, Strand TE, Linklater K, Robinson D, Møller H. National comparisons of lung cancer survival in England, Norway and Sweden 2001-2004: differences occur early in follow-up. Thorax. 65: 436-41. PMID 20435867 DOI: 10.1136/Thx.2009.124222  0.378
2009 Treasure T, Waller D, Tan C, Entwisle J, O'Brien M, O'Byrne K, Thomas G, Snee M, Spicer J, Landau D, Lang-Lazdunski L, Bliss J, Peckitt C, Rogers S, Marriage Née Denholm E, et al. The Mesothelioma and Radical surgery randomized controlled trial: the Mars feasibility study. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 4: 1254-8. PMID 19661833 DOI: 10.1097/Jto.0B013E3181Ae26Ae  0.317
2009 Reid AH, Protheroe A, Attard G, Hayward N, Vidal L, Spicer J, Shaw HM, Bone EA, Carter J, Hooftman L, Harris A, De Bono JS. A first-in-man phase i and pharmacokinetic study on CHR-2797 (Tosedostat), an inhibitor of M1 aminopeptidases, in patients with advanced solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 15: 4978-85. PMID 19638462 DOI: 10.1158/1078-0432.Ccr-09-0306  0.346
2009 Mukherji D, Spicer J. Second-generation epidermal growth factor tyrosine kinase inhibitors in non-small cell lung cancer. Expert Opinion On Investigational Drugs. 18: 293-301. PMID 19243280 DOI: 10.1517/13543780902762843  0.376
2009 Karagiannis P, Singer J, Hunt J, Gan SK, Rudman SM, Mechtcheriakova D, Knittelfelder R, Daniels TR, Hobson PS, Beavil AJ, Spicer J, Nestle FO, Penichet ML, Gould HJ, Jensen-Jarolim E, et al. Characterisation of an engineered trastuzumab IgE antibody and effector cell mechanisms targeting HER2/neu-positive tumour cells. Cancer Immunology, Immunotherapy : Cii. 58: 915-30. PMID 18941743 DOI: 10.1007/S00262-008-0607-1  0.317
2009 Burbridge S, Wilkie S, Davies D, Chiapero‐Stanke L, Maher J, Spicer J. Abstract C242: Development of adoptive‐T‐cell therapy for prostate cancer incorporating a novel chimeric cytokine receptor Molecular Cancer Therapeutics. 8. DOI: 10.1158/1535-7163.Targ-09-C242  0.332
2009 Stavridi F, Eestila S, Merchant S, Cane P, Spicer J. Use of erlotinib in patients selected using clinical criteria in the 2nd and 3rd line treatment of non-small cell lung cancer (NSCLC) Lung Cancer. 63. DOI: 10.1016/S0169-5002(09)70015-7  0.416
2009 Soffin E, Alam S, Hogan V, Rudman S, Spicer J. Treatment-associated deaths and mortality following chemotherapy for non-small cell lung cancer Lung Cancer. 63. DOI: 10.1016/S0169-5002(09)70013-3  0.371
2008 Kyle F, Spicer J. Targeted therapies in non-small cell lung cancer. Cancer Imaging : the Official Publication of the International Cancer Imaging Society. 8: 199-205. PMID 19028612 DOI: 10.1102/1470-7330.2008.0027  0.413
2008 Hughes S, Liong J, Miah A, Ahmad S, Leslie M, Harper P, Prendiville J, Shamash J, Subramaniam R, Gaya A, Spicer J, Landau D. A brief report on the safety study of induction chemotherapy followed by synchronous radiotherapy and cetuximab in stage III non-small cell lung cancer (NSCLC): SCRATCH study. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 3: 648-51. PMID 18520806 DOI: 10.1097/Jto.0B013E3181757A60  0.446
2007 Lord R, Nair S, Schache A, Spicer J, Somaihah N, Khoo V, Pandha H. Low Dose Metronomic Oral Cyclophosphamide for Hormone Resistant Prostate Cancer: A Phase II Study The Journal of Urology. 177: 2136-2140. PMID 17509300 DOI: 10.1016/J.Juro.2007.01.143  0.379
2007 Spicer J, Chowdhury S, Harper P. Targeting novel and established therapies for non-small cell lung cancer. Cancer Letters. 250: 9-16. PMID 17030089 DOI: 10.1016/J.Canlet.2006.09.001  0.435
2007 Spicer J, Ellis P. Towards optimal endocrine therapy for hormone-sensitive breast cancer: Initial versus sequential adjuvant aromatase inhibition Cancer Letters. 248: 165-174. PMID 16919870 DOI: 10.1016/J.Canlet.2006.07.002  0.321
2007 Spicer J, Futreal A, Bono JD. Pharmacogenomics of non-small cell lung cancer Current Pharmacogenomics. 5: 228-234. DOI: 10.2174/157016007781669178  0.374
2007 Protheroe A, Reid A, Attard G, Davies A, Spicer J, Vidal L, Bone E, Hooftman L, Harris A, De-Bono J. First in-human phase 1 trial of a novel amino-peptidase inhibitor, CHR-2797 Journal of Clinical Oncology. 25: 3537-3537. DOI: 10.1200/Jco.2007.25.18_Suppl.3537  0.383
2007 Reid AH, Tang A, Spicer J, Gallerani E, Mears D, Settatree S, Yap TA, Puchalski T, Harrison M, De-Bono JS. An open, pharmacokinetic (PK) and mass balance study of 14C-AZD2171, incorporating DCE-CT evaluations Journal of Clinical Oncology. 25: 14140-14140. DOI: 10.1200/Jco.2007.25.18_Suppl.14140  0.319
2007 Shaw HM, Molife LR, Spicer J, Karavasilis V, Marriott C, Ong TJ, Tate L, Brendel E, Christensen O, Bono JSd. A phase Ib study of telatinib (BAY 57–9352), a VEGFR-2 inhibitor, in combination with docetaxel in patients with advanced solid tumours Journal of Clinical Oncology. 25: 14035-14035. DOI: 10.1200/Jco.2007.25.18_Suppl.14035  0.325
2007 Spicer J, Calvert H, Vidal L, Azribi F, Perrett R, Shahidi M, Temple G, Futreal A, Bono JD, Plummer R. D7-02: Activity of BIBW2992, an oral irreversible dual EGFR/HER2 inhibitor, in non-small cell lung cancer (NSCLC) with mutated EGFR Journal of Thoracic Oncology. 2. DOI: 10.1097/01.Jto.0000283293.26207.0A  0.38
2007 Plummer R, Vidal L, Perrett R, Spicer J, Stopfer P, Shahidi M, Temple G, Futreal A, Calvert H, Bono Jd. 703 POSTER A phase I and pharmacokinetic (PK) study of BIBW 2992, an oral irreversible dual EGFR/HER2 inhibitor Ejc Supplements. 5: 108. DOI: 10.1016/S1359-6349(07)70502-5  0.319
2006 Reid A, Protheroe A, Attard G, Cowsill C, Spicer J, Vidal L, Bone E, Hooftman L, Harris A, De-Bono JS. A phase 1 dose finding study of CHR-2797, an inhibitor of M1 aminopeptidases, in patients with advanced solid tumours Journal of Clinical Oncology. 24: 3053-3053. DOI: 10.1200/Jco.2006.24.18_Suppl.3053  0.387
2006 Attard G, Fong PC, Molife R, Reade S, Shaw H, Reid A, Spicer J, Hamlin J, Gualberto A, Bono JSD. Phase I trial involving the pharmacodynamic (PD) study of circulating tumour cells, of CP-751,871 (C), a monoclonal antibody against the insulin-like growth factor 1 receptor (IGF-1R), with docetaxel (D) in patients (p) with advanced cancer Journal of Clinical Oncology. 24: 3023-3023. DOI: 10.1200/Jco.2006.24.18_Suppl.3023  0.321
2006 de Bono J, Fong P, Boss D, Spicer J, Roelvink M, Tutt A, Mortimer P, O'Connor M, M J, Kaye S. 503 POSTER Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evalutation of an oral small molecule inhibitor of Poly ADP-Ribose Polymerase (PARP), Ku in patients (p) with advance tumours European Journal of Cancer Supplements. 4: 153. DOI: 10.1016/S1359-6349(06)70508-0  0.317
2006 Fong PC, Molife RL, Spicer J, Yap TA, Settatree S, Digue L, Attard G, Karavasilis V, Gualberto A, Bono JSd. 196 POSTER A phase I trial incorporating the pharmacodynamic (PD) study of circulating tumour cells (CTC) of CP-751,871 (C), a monoclonal antibody against the insulin-like growth factor 1 receptor (IGF-1R), in combination with docetaxel (D) in patients (p) with advanced cancer Ejc Supplements. 4: 61-62. DOI: 10.1016/S1359-6349(06)70201-4  0.347
2006 Spicer J, Banerji U, Hanwell J, Judson I. Stable disease for four years in metastatic malignant melanoma treated with the heat shock protein inhibitor 17-AAG Targeted Oncology. 1: 54-55. DOI: 10.1007/S11523-005-0008-8  0.34
2005 Cheong KA, Chrystal K, Spicer J, Harper PG. A single centre retrospective review of oral cyclophosphamide in hormone-refractory prostate cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 23: 4781. PMID 27943818 DOI: 10.1200/Jco.2005.23.16_Suppl.4781  0.382
2005 Spicer J, Harper P. Targeted therapies for non-small cell lung cancer International Journal of Clinical Practice. 59: 1055-1062. PMID 16115182 DOI: 10.1111/J.1742-1241.2005.00622.X  0.401
2005 Spicer J, Harries M, Ellis P. Adjuvant trastuzumab for HER2-positive breast cancer. Lancet (London, England). 366: 634. PMID 16112298 DOI: 10.1016/S0140-6736(05)67134-6  0.353
2005 Cheong K, Spicer J, Chowdhury S, Harper P. Combination therapy versus single agent chemotherapy in non-small cell lung cancer. Expert Opinion On Pharmacotherapy. 6: 1693-700. PMID 16086655 DOI: 10.1517/14656566.6.10.1693  0.404
2005 Spicer J, Plunkett T, Somaiah N, Chan S, Kendall A, Bolunwu N, Pandha H. Phase II study of oral capecitabine in patients with hormone-refractory prostate cancer. Prostate Cancer and Prostatic Diseases. 8: 364-8. PMID 16077679 DOI: 10.1038/Sj.Pcan.4500821  0.38
2004 Spicer J, Quatan N, Plunkett T, Pandha H. Cellular immunotherapy for cancer: current concepts and clinical perspectives Monitoring immune responses and clinical trials: part II. Clinical Oncology. 16: 395-404. PMID 15487131 DOI: 10.1016/J.Clon.2004.03.014  0.306
2004 Quatan N, Spicer J, Plunkett T, Pandha H. Cellular immunotherapy for cancer: current concepts and clinical perspectives scientific basis and approaches for therapeutic cancer vaccines. Part I. Clinical Oncology. 16: 356-365. PMID 15341440 DOI: 10.1016/J.Clon.2004.03.013  0.37
2004 Spicer J, Smith P, Maclennan K, Hoskin P, Hancock B, Linch D, Pettengell R. Long-term follow-up of patients treated with radiotherapy alone for early-stage histologically aggressive non-Hodgkin's lymphoma. British Journal of Cancer. 90: 1151-5. PMID 15026794 DOI: 10.1038/Sj.Bjc.6601675  0.354
Low-probability matches (unlikely to be authored by this person)
2016 Plummer R, Verheul HM, Langenberg M, Leunen K, Molife LR, Rolfo C, Grundtvig-Soerensen P, Greve JD, Rottey S, Jerusalem G, Itiliano A, Spicer J, Dirix L, Goessl C, Birkett J, et al. Pharmacokinetic (PK) effects and safety of olaparib in combination with tamoxifen, anastrozole, or letrozole: Phase I study. Journal of Clinical Oncology. 34: 2562-2562. DOI: 10.1200/Jco.2016.34.15_Suppl.2562  0.299
2018 Jordan EJ, Spicer J, Sarker D. Delayed adverse events in phase I trials of molecularly targeted and cytotoxic agents. Oncotarget. 9: 33961-33971. PMID 30338038 DOI: 10.18632/Oncotarget.26104  0.299
2015 Achkova D, Spicer J, Maher J. Abstract 3144: Development of immunotherapy for anaplastic large cell lymphoma (ALCL) using CSF1R retargeted human T lymphocytes Cancer Research. 75: 3144-3144. DOI: 10.1158/1538-7445.Am2015-3144  0.296
2015 Spicer J, Awada A, Brunsvig P, Saunders A, Olsen WM, Nicolaisen B, Rekdal O, Laruelle M, Marjuadi F, Vakili J, Aftimos P, Barthelemy P, Deva S, Baurain JF. 528 Intratumoural treatment with LTX-, an oncolytic peptide immunotherapy, in patients with advanced metastatic disease induces CD8 effector cells and regression in some injected tumours European Journal of Cancer. 51. DOI: 10.1016/S0959-8049(16)30329-X  0.295
2004 Stebbing J, Bower M, Gazzard B, Wildfire A, Pandha H, Dalgleish A, Spicer J. The common heat shock protein receptor CD91 is up‐regulated on monocytes of advanced melanoma slow progressors Clinical and Experimental Immunology. 138: 312-316. PMID 15498042 DOI: 10.1111/J.1365-2249.2004.02619.X  0.295
2018 Traylor M, Walker JL, Corrigan AA, Hernandez MA, Newhouse SJ, Folarin AA, Patel H, Ross PJ, Sanderson JD, Spicer J, Prescott NJ, Mathew CG, Marinaki AM, Lewis CM. Exome array analysis of adverse reactions to fluoropyrimidine-based therapy for gastrointestinal cancer. Plos One. 13: e0188911. PMID 29715290 DOI: 10.1371/Journal.Pone.0188911  0.295
2015 Spicer J, Tischer B, Peters M. Lba2_Pregfr Mutation Testing And Oncologist Treatment Choice In Advanced Nsclc: Global Trends And Differences Annals of Oncology. 26. DOI: 10.1093/Annonc/Mdv128.04  0.294
2009 Josephs D, Spicer J, O'Doherty M. Molecular imaging in clinical trials. Targeted Oncology. 4: 151-68. PMID 19768637 DOI: 10.1007/S11523-009-0117-X  0.286
2015 Morgan R, Simpson G, Gray S, Gillett C, Tabi Z, Spicer J, Harrington KJ, Pandha HS. HOX transcription factors are potential targets and markers in malignant mesothelioma. Bmc Cancer. 16: 85. PMID 26867567 DOI: 10.1186/S12885-016-2106-7  0.285
2012 Couchman L, Birch M, Ireland R, Corrigan A, Wickramasinghe S, Josephs D, Spicer J, Flanagan RJ. An automated method for the measurement of a range of tyrosine kinase inhibitors in human plasma or serum using turbulent flow liquid chromatography-tandem mass spectrometry. Analytical and Bioanalytical Chemistry. 403: 1685-95. PMID 22526649 DOI: 10.1007/S00216-012-5970-2  0.285
2010 Basu B, Ang J, Blanco M, Dowsett M, Spicer J, Tutt A, Johnston S, Wan S, Bono JD, Swanton C. 655 Preliminary report of efficacy of abiraterone acetate in patients with estrogen (ER) or androgen receptor (AR) positive, advanced breast carcinoma resistant to standard endocrine therapies Ejc Supplements. 8: 204-205. DOI: 10.1016/S1359-6349(10)72362-4  0.282
2021 Abdul-Jawad S, Baù L, Alaguthurai T, Del Molino Del Barrio I, Laing AG, Hayday TS, Monin L, Muñoz-Ruiz M, McDonald L, Francos Quijorna I, McKenzie D, Davis R, Lorenc A, Chan JNE, Ryan S, ... ... Spicer J, et al. Acute immune signatures and their legacies in severe acute respiratory syndrome coronavirus-2 infected cancer patients. Cancer Cell. PMID 33476581 DOI: 10.1016/j.ccell.2021.01.001  0.282
2022 Luigi Banna G, Addeo A, Zygoura P, Tsourti Z, Popat S, Curioni-Fontecedro A, Nadal E, Shah R, Pope A, Fisher P, Spicer J, Roy A, Gilligan D, Gautschi O, Janthur WD, et al. A prognostic score for patients with malignant pleural mesothelioma (MPM) receiving second-line immunotherapy or chemotherapy in the ETOP 9-15 PROMISE-meso phase III trial. Lung Cancer (Amsterdam, Netherlands). 169: 77-83. PMID 35660972 DOI: 10.1016/j.lungcan.2022.05.018  0.281
2010 Tan C, Barrington S, Rankin S, Landau D, Pilling J, Spicer J, Cane P, Lang-Lazdunski L. Role of integrated 18-fluorodeoxyglucose position emission tomography-computed tomography in patients surveillance after multimodality therapy of malignant pleural mesothelioma. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 385-8. PMID 20087231 DOI: 10.1097/Jto.0B013E3181Cbf465  0.281
2013 Karagiannis P, Gilbert AE, Josephs DH, Ali N, Dodev T, Saul L, Correa I, Roberts L, Beddowes E, Koers A, Hobbs C, Ferreira S, Geh JL, Healy C, Harries M, ... ... Spicer JF, et al. IgG4 subclass antibodies impair antitumor immunity in melanoma. The Journal of Clinical Investigation. 123: 1457-74. PMID 23454746 DOI: 10.1172/Jci65579  0.281
2017 Love SB, Brown S, Weir CJ, Harbron C, Yap C, Gaschler-Markefski B, Matcham J, Caffrey L, McKevitt C, Clive S, Craddock C, Spicer J, Cornelius V. Embracing model-based designs for dose-finding trials. British Journal of Cancer. PMID 28664918 DOI: 10.1038/Bjc.2017.186  0.28
2015 Kapp JR, Diss T, Spicer J, Gandy M, Schrijver I, Jennings LJ, Li MM, Tsongalis GJ, de Castro DG, Bridge JA, Wallace A, Deignan JL, Hing S, Butler R, Verghese E, et al. Variation in pre-PCR processing of FFPE samples leads to discrepancies in BRAF and EGFR mutation detection: a diagnostic RING trial. Journal of Clinical Pathology. 68: 111-8. PMID 25430497 DOI: 10.1136/Jclinpath-2014-202644  0.277
2016 Simon ST, Weingärtner V, Higginson IJ, Benalia H, Gysels M, Murtagh FE, Spicer J, Linde P, Voltz R, Bausewein C. "I Can Breathe Again!" Patients' Self-Management Strategies for Episodic Breathlessness in Advanced Disease, Derived from Qualitative Interviews. Journal of Pain and Symptom Management. PMID 27220949 DOI: 10.1016/J.Jpainsymman.2016.02.016  0.277
2019 Perez JMT, Felip E, Brunsvig P, Helland A, Viñolas N, Aix SP, Costa EC, Gomez MD, Arriola E, Campelo RG, Spicer J, Thompson JR, Granados ALO, Holt RJ, Lorens JB, et al. Efficacy results of selective AXL inhibitor bemcentinib with pembrolizumab following chemo in patients with NSCLC Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz260.098  0.277
2015 Hall PE, Spicer J, Popat S. Rationale for targeting the ErbB family of receptors in patients with advanced squamous cell carcinoma of the lung. Future Oncology (London, England). 11: 2175-91. PMID 26039665 DOI: 10.2217/fon.15.110  0.274
2020 Sarker D, Plummer R, Meyer T, Sodergren M, Basu B, Chee CE, Huang KW, Palmer DH, Ma YT, Evans TRJ, Spalding DR, Pai M, Sharma R, Pinato DJ, Spicer J, et al. MTL-CEBPA, a small activating RNA therapeutic up-regulating C/EBP-α, in patients with advanced liver cancer: a first-in-human, multi-centre, open-label, phase I trial. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 32357963 DOI: 10.1158/1078-0432.Ccr-20-0414  0.27
2020 Spicer J, Chamberlain C, Papa S. Provision of cancer care during the COVID-19 pandemic. Nature Reviews. Clinical Oncology. PMID 32296166 DOI: 10.1038/S41571-020-0370-6  0.269
2013 Mohd Noor A, Sarker D, Vizor S, McLennan B, Hunter S, Suder A, Moller H, Spicer JF, Papa S. Effect of patient socioeconomic status on access to early-phase cancer trials. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 31: 224-30. PMID 23213088 DOI: 10.1200/JCO.2012.45.0999  0.267
2020 Bax HJ, Chauhan J, Stavraka C, Khiabany A, Nakamura M, Pellizzari G, Ilieva KM, Lombardi S, Gould HJ, Corrigan CJ, Till SJ, Katugampola S, Jones PS, Barton C, Winship A, ... ... Spicer JF, et al. Basophils from Cancer Patients Respond to Immune Stimuli and Predict Clinical Outcome. Cells. 9. PMID 32645919 DOI: 10.3390/Cells9071631  0.266
2006 Vidal L, Pandha H, Spicer J, Harrington KJ, Allen S, Leader D, Coffey M, Thompson B, Kaye S, De-Bono J. A phase I study of reolysin given intravenously to patients with advanced malignancies Journal of Clinical Oncology. 24: 3064-3064. DOI: 10.1200/Jco.2006.24.18_Suppl.3064  0.265
2015 Thayaparan T, Stegen S, Parente Pereira Puri A, Petrovic R, Spicer J, Maher J. 53: Immunotherapy of malignant pleural mesothelioma using MET specific T-cells Lung Cancer. 87: S21. DOI: 10.1016/S0169-5002(14)70075-3  0.263
2018 Spicer J, Kwatra V, Verma C, Ioannou K, Goldstein R, Brier T, Eremin J, Zareian N, Walker L, Lobo D, Farzaneh F, Eremin O. Phase I trial of a novel hTERT vaccination strategy addressing T effector cells and immune-suppressor mechanisms. Annals of Oncology. 29. DOI: 10.1093/Annonc/Mdy288.030  0.261
2016 Cheung A, Bax HJ, Josephs DH, Ilieva KM, Pellizzari G, Opzoomer J, Bloomfield J, Fittall M, Grigoriadis A, Figini M, Canevari S, Spicer JF, Tutt AN, Karagiannis SN. Targeting folate receptor alpha for cancer treatment. Oncotarget. PMID 27248175 DOI: 10.18632/oncotarget.9651  0.259
2006 Fong PC, Spicer J, Reade S, Reid A, Vidal L, Schellens JH, Tutt A, Harris PA, Kaye S, Bono JSD. Phase I pharmacokinetic (PK) and pharmacodynamic (PD) evaluation of a small molecule inhibitor of Poly ADP-Ribose Polymerase (PARP), KU-0059436 (Ku) in patients (p) with advanced tumours Journal of Clinical Oncology. 24: 3022-3022. DOI: 10.1200/Jco.2006.24.18_Suppl.3022  0.258
2022 Kindler HL, Novello S, Bearz A, Ceresoli GL, Aerts JGJV, Spicer J, Taylor P, Nackaerts K, Greystoke A, Jennens R, Calabrò L, Burgers JA, Santoro A, Cedrés S, Serwatowski P, et al. Anetumab ravtansine versus vinorelbine in patients with relapsed, mesothelin-positive malignant pleural mesothelioma (ARCS-M): a randomised, open-label phase 2 trial. The Lancet. Oncology. 23: 540-552. PMID 35358455 DOI: 10.1016/S1470-2045(22)00061-4  0.257
2014 Soultati A, Josephs DH, Spicer JF. Effect of onartuzumab added to erlotinib on metastasis in patients with lung cancer. Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology. 32: 3781. PMID 25332242 DOI: 10.1200/JCO.2013.54.3413  0.257
2022 Chauhan J, Stavraka C, Grandits M, Palhares LCGF, Josephs DH, Lacy KE, Spicer J, Bax HJ, Karagiannis SN. Clinical and Translational Significance of Basophils in Patients with Cancer. Cells. 11. PMID 35159247 DOI: 10.3390/cells11030438  0.251
2011 Bliss JM, Coombes G, Darlison L, Edwards J, Entwisle J, Kilburn LS, Landau D, Lang-Lazdunski L, O'Brien M, O'Byrne K, Peto J, Senan S, Snee M, Spicer J, Tan C, et al. The MARS feasibility trial: Conclusions not supported by data - Authors' reply The Lancet Oncology. 12: 1094-1095. DOI: 10.1016/S1470-2045(11)70308-4  0.246
2003 Spicer J, Rayter S, Young N, Elliott R, Ashworth A, Smith D. Regulation of the Wnt signalling component PAR1A by the Peutz-Jeghers syndrome kinase LKB1. Oncogene. 22: 4752-6. PMID 12879020 DOI: 10.1038/Sj.Onc.1206669  0.245
2005 Spicer J. Technology evaluation: nimotuzumab, the Center of Molecular Immunology/YM BioSciences/Oncoscience. Current Opinion in Molecular Therapeutics. 7: 182-91. PMID 15844627  0.245
2016 Saul L, Karagiannis P, Ilieva K, Correa I, Geh J, Healy C, Spicer J, Nestle F, Lacy KE, Karagiannis S. 483 Alternative activation of cutaneous B cells and IgG antibody subclass polarisation in melanoma Journal of Investigative Dermatology. 136. DOI: 10.1016/J.Jid.2016.06.505  0.241
1999 Smith DP, Spicer J, Smith A, Swift S, Ashworth A. The mouse Peutz-Jeghers syndrome gene Lkb1 encodes a nuclear protein kinase. Human Molecular Genetics. 8: 1479-85. PMID 10400995 DOI: 10.1093/Hmg/8.8.1479  0.241
2012 Karagiannis P, Gilbert A, Dodev T, Josephs D, Alkathiri N, Dafou D, Ainali C, Koers A, Saul L, Tsoka S, Spicer J, Gould H, Beavil A, Nestle F, Karagiannis S. IgE antibodies targeting a major melanoma antigen are more effective than IgG antibodies for tumour protection in a humanized melanoma model British Journal of Dermatology. 166. DOI: 10.1111/J.1365-2133.2012.10903.X  0.239
2001 Smith DP, Rayter SI, Niederlander C, Spicer J, Jones CM, Ashworth A. LIP1, a cytoplasmic protein functionally linked to the Peutz-Jeghers syndrome kinase LKB1. Human Molecular Genetics. 10: 2869-77. PMID 11741830 DOI: 10.1093/Hmg/10.25.2869  0.238
2013 van Schalkwyk MC, Papa SE, Jeannon JP, Guerrero Urbano T, Spicer JF, Maher J. Design of a phase I clinical trial to evaluate intratumoral delivery of ErbB-targeted chimeric antigen receptor T-cells in locally advanced or recurrent head and neck cancer. Human Gene Therapy. Clinical Development. 24: 134-42. PMID 24099518 DOI: 10.1089/Humc.2013.144  0.236
2010 Irshad S, McLean E, Rankin S, Barrington S, Santis G, Spicer J, Lang-Lazdunski L. Unilateral diffuse idiopathic pulmonary neuroendocrine cell hyperplasia and multiple carcinoids treated with surgical resection. Journal of Thoracic Oncology : Official Publication of the International Association For the Study of Lung Cancer. 5: 921-3. PMID 20502273 DOI: 10.1097/Jto.0B013E3181Db6Ddd  0.234
2021 Russell B, Moss CL, Shah V, Ko TK, Palmer K, Sylva R, George G, Monroy-Iglesias MJ, Patten P, Ceesay MM, Benjamin R, Potter V, Pagliuca A, Papa S, Irshad S, ... ... Spicer J, et al. Risk of COVID-19 death in cancer patients: an analysis from Guy's Cancer Centre and King's College Hospital in London. British Journal of Cancer. PMID 34400804 DOI: 10.1038/s41416-021-01500-z  0.234
2021 McCraw AJ, Chauhan J, Bax HJ, Stavraka C, Osborn G, Grandits M, López-Abente J, Josephs DH, Spicer J, Wagner GK, Karagiannis SN, Chenoweth A, Crescioli S. Insights from IgE Immune Surveillance in Allergy and Cancer for Anti-Tumour IgE Treatments. Cancers. 13. PMID 34503270 DOI: 10.3390/cancers13174460  0.234
2021 Russell B, Moss CL, Palmer K, Sylva R, D'Souza A, Wylie H, Haire A, Cahill F, Steel R, Hoyes A, Wilson I, Macneil A, Shifa B, Monroy-Iglesias MJ, Papa S, ... ... Spicer J, et al. COVID-19 Risk Factors for Cancer Patients: A First Report with Comparator Data from COVID-19 Negative Cancer Patients. Cancers. 13. PMID 34069565 DOI: 10.3390/cancers13102479  0.233
2019 de Bono JS, Concin N, Hong DS, Thistlethwaite FC, Machiels JP, Arkenau HT, Plummer R, Jones RH, Nielsen D, Windfeld K, Ghatta S, Slomovitz BM, Spicer JF, Yachnin J, Ang JE, et al. Tisotumab vedotin in patients with advanced or metastatic solid tumours (InnovaTV 201): a first-in-human, multicentre, phase 1-2 trial. The Lancet. Oncology. PMID 30745090 DOI: 10.1016/S1470-2045(18)30859-3  0.231
2019 Hong DS, Concin N, Vergote I, de Bono JS, Slomovitz BM, Drew Y, Arkenau HT, Machiels JP, Spicer J, Jones R, Forster M, Cornez N, Gennigens C, Johnson ML, Thistlethwaite FC, et al. Tisotumab Vedotin in Previously Treated Recurrent or Metastatic Cervical Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 31796521 DOI: 10.1158/1078-0432.CCR-19-2962  0.231
2019 Popat S, Curioni-Fontecedro A, Polydoropoulou V, Shah R, O’Brien M, Pope A, Fisher P, Spicer J, Roy A, Gilligan D, Gautschi O, Nadal E, Janthur W-, Castro RL, Campelo RG, et al. A multicentre randomized phase III trial comparing pembrolizumab (P) vs single agent chemotherapy (CT) for advanced pre-treated malignant pleural mesothelioma (MPM): Results from the European Thoracic Oncology Platform (ETOP 9-15) PROMISE-meso trial Annals of Oncology. 30. DOI: 10.1093/Annonc/Mdz394.091  0.229
2004 Spicer J, Ashworth A. LKB1 kinase: master and commander of metabolism and polarity. Current Biology : Cb. 14: R383-5. PMID 15186763 DOI: 10.1016/J.Cub.2004.05.012  0.226
2017 Ilieva KM, Cheung A, Mele S, Chiaruttini G, Crescioli S, Griffin M, Nakamura M, Spicer JF, Tsoka S, Lacy KE, Tutt ANJ, Karagiannis SN. Chondroitin Sulfate Proteoglycan 4 and Its Potential As an Antibody Immunotherapy Target across Different Tumor Types. Frontiers in Immunology. 8: 1911. PMID 29375561 DOI: 10.3389/fimmu.2017.01911  0.226
2022 Russell B, Moss C, Tsotra E, Gousis C, Josephs D, Enting D, Karampera C, Khan M, Roca J, Sita-Lumsden A, Owczarczyk K, Wylie H, Haire A, Smith D, Zaki K, ... ... Spicer J, et al. The Impact of COVID-19 on the Delivery of Systemic Anti-Cancer Treatment at Guy's Cancer Centre. Cancers. 14. PMID 35053432 DOI: 10.3390/cancers14020266  0.223
2021 Pellizzari G, Martinez O, Crescioli S, Page R, Di Meo A, Mele S, Chiaruttini G, Hoinka J, Batruch I, Prassas I, Grandits M, López-Abente J, Bugallo-Blanco E, Ward M, Bax HJ, ... ... Spicer J, et al. Immunotherapy using IgE or CAR T cells for cancers expressing the tumor antigen SLC3A2. Journal For Immunotherapy of Cancer. 9. PMID 34112739 DOI: 10.1136/jitc-2020-002140  0.223
2016 Bax HJ, Josephs DH, Pellizzari G, Spicer JF, Montes A, Karagiannis SN. Therapeutic targets and new directions for antibodies developed for ovarian cancer. Mabs. 0. PMID 27494775 DOI: 10.1080/19420862.2016.1219005  0.222
2023 Morton C, Sullivan R, Sarker D, Posner J, Spicer J. Revitalising cancer trials post-pandemic: time for reform. British Journal of Cancer. 1-6. PMID 36959378 DOI: 10.1038/s41416-023-02224-y  0.222
2019 Nakamura M, Bax HJ, Scotto D, Souri EA, Sollie S, Harris RJ, Hammar N, Walldius G, Winship A, Ghosh S, Montes A, Spicer JF, Van Hemelrijck M, Josephs DH, Lacy KE, et al. Immune mediator expression signatures are associated with improved outcome in ovarian carcinoma. Oncoimmunology. 8: e1593811. PMID 31069161 DOI: 10.1080/2162402X.2019.1593811  0.221
2020 Pellizzari G, Bax HJ, Josephs DH, Gotovina J, Jensen-Jarolim E, Spicer JF, Karagiannis SN. Harnessing Therapeutic IgE Antibodies to Re-educate Macrophages against Cancer. Trends in Molecular Medicine. 26: 615-626. PMID 32470387 DOI: 10.1016/j.molmed.2020.03.002  0.221
2018 Lang-Lazdunski L, Tokaca N, Lal KR, Steele J, Newsom-Davis T, Landau D, Spicer J, Popat S. 216PD Should radical surgery be performed in non-epithelioid malignant pleural mesothelioma? Journal of Thoracic Oncology. 13. DOI: 10.1016/S1556-0864(18)30489-1  0.221
2018 Muliaditan T, Opzoomer JW, Caron J, Okesola M, Kosti P, Lall S, Van Hemelrijck M, Dazzi F, Tutt A, Grigoriadis A, Gillett C, Madden SF, Burchell JM, Kordasti S, Diebold SS, ... Spicer J, et al. Repurposing tin mesoporphyrin as an immune checkpoint inhibitor shows therapeutic efficacy in preclinical models of cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 29339440 DOI: 10.1158/1078-0432.CCR-17-2587  0.22
2020 Bax HJ, Khiabany A, Stavraka C, Pellizzari G, Chan Wah Hak C, Robinson A, Ilieva KM, Woodman N, Naceur-Lombardelli C, Gillett C, Pinder S, Gould HJ, Corrigan CJ, Till SJ, Katugampola S, ... ... Spicer JF, et al. Basophil activation test in cancer patient blood evaluating potential hypersensitivity to an anti-tumor IgE therapeutic candidate. Allergy. PMID 32086828 DOI: 10.1111/all.14245  0.218
1997 Patterson H, Barnes D, Gill S, Spicer J, Fisher C, Thomas M, Grimer R, Fletcher C, Gusterson B, Cooper C. Amplification and Over-Expression of the MDM2 Gene in Human Soft Tissue Tumours. Sarcoma. 1: 17-22. PMID 18521196 DOI: 10.1080/13577149778434  0.217
2014 Ilieva KM, Correa I, Josephs DH, Karagiannis P, Egbuniwe IU, Cafferkey MJ, Spicer JF, Harries M, Nestle FO, Lacy KE, Karagiannis SN. Effects of BRAF mutations and BRAF inhibition on immune responses to melanoma. Molecular Cancer Therapeutics. 13: 2769-83. PMID 25385327 DOI: 10.1158/1535-7163.MCT-14-0290  0.208
2004 Spicer J. Technology evaluation: pertuzumab, Roche/Genentech/Chugai. Current Opinion in Molecular Therapeutics. 6: 337-43. PMID 15264437  0.208
2021 Fox L, Monroy-Iglesias MJ, Aggarwal A, Haire K, Purushotham A, Spicer J, Papa S, Rigg A, Dolly S, Sullivan R, Van Hemelrijck M. Association between COVID-19 burden and delays to diagnosis and treatment of cancer patients in England. Journal of Cancer Policy. 31: 100316. PMID 35559868 DOI: 10.1016/j.jcpo.2021.100316  0.208
2022 Bax HJ, Chauhan J, Stavraka C, Santaolalla A, Osborn G, Khiabany A, Grandits M, López-Abente J, Palhares LCGF, Chan Wah Hak C, Robinson A, Pope A, Woodman N, Naceur-Lombardelli C, Malas S, ... ... Spicer J, et al. Folate receptor alpha in ovarian cancer tissue and patient serum is associated with disease burden and treatment outcomes. British Journal of Cancer. PMID 36402875 DOI: 10.1038/s41416-022-02031-x  0.207
2019 Khair DO, Bax HJ, Mele S, Crescioli S, Pellizzari G, Khiabany A, Nakamura M, Harris RJ, French E, Hoffmann RM, Williams IP, Cheung A, Thair B, Beales CT, Touizer E, ... ... Spicer JF, et al. Combining Immune Checkpoint Inhibitors: Established and Emerging Targets and Strategies to Improve Outcomes in Melanoma. Frontiers in Immunology. 10: 453. PMID 30941125 DOI: 10.3389/fimmu.2019.00453  0.206
2017 Griffin M, Scotto D, Josephs DH, Mele S, Crescioli S, Bax HJ, Pellizzari G, Wynne MD, Nakamura M, Hoffmann RM, Ilieva KM, Cheung A, Spicer JF, Papa S, Lacy KE, et al. BRAF inhibitors: resistance and the promise of combination treatments for melanoma. Oncotarget. 8: 78174-78192. PMID 29100459 DOI: 10.18632/oncotarget.19836  0.206
2017 Karagiannis SN, Josephs DH, Bax HJ, Spicer JF. Therapeutic IgE Antibodies: Harnessing a Macrophage-Mediated Immune Surveillance Mechanism against Cancer. Cancer Research. PMID 28526770 DOI: 10.1158/0008-5472.CAN-17-0428  0.206
2020 Hoffmann RM, Mele S, Cheung A, Larcombe-Young D, Bucaite G, Sachouli E, Zlatareva I, Morad HOJ, Marlow R, McDonnell JM, Figini M, Lacy KE, Tutt AJN, Spicer JF, Thurston DE, et al. Rapid conjugation of antibodies to toxins to select candidates for the development of anticancer Antibody-Drug Conjugates (ADCs). Scientific Reports. 10: 8869. PMID 32483228 DOI: 10.1038/S41598-020-65860-X  0.205
2021 Spicer J, Marabelle A, Baurain JF, Jebsen NL, Jøssang DE, Awada A, Kristeleit R, Loirat D, Lazaridis G, Jungels C, Brunsvig P, Nicolaisen B, Saunders A, Patel H, Galon J, et al. Safety, anti-tumor activity and T-cell responses in a dose-ranging phase 1 trial of the oncolytic peptide LTX-315 in patients with solid tumors. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 33542073 DOI: 10.1158/1078-0432.CCR-20-3435  0.204
2021 Monin L, Laing AG, Muñoz-Ruiz M, McKenzie DR, Del Molino Del Barrio I, Alaguthurai T, Domingo-Vila C, Hayday TS, Graham C, Seow J, Abdul-Jawad S, Kamdar S, Harvey-Jones E, Graham R, Cooper J, ... ... Spicer J, et al. Safety and immunogenicity of one versus two doses of the COVID-19 vaccine BNT162b2 for patients with cancer: interim analysis of a prospective observational study. The Lancet. Oncology. PMID 33930323 DOI: 10.1016/S1470-2045(21)00213-8  0.204
2017 Thayaparan T, Petrovic RM, Achkova DY, Zabinski T, Davies DM, Klampatsa A, Parente-Pereira AC, Whilding LM, van der Stegen SJ, Woodman N, Sheaff M, Cochran JR, Spicer JF, Maher J. CAR T-cell immunotherapy of MET-expressing malignant mesothelioma. Oncoimmunology. 6: e1363137. PMID 29209570 DOI: 10.1080/2162402X.2017.1363137  0.203
2020 Szlosarek PW, Phillips MM, Pavlyk I, Steele J, Shamash J, Spicer J, Kumar S, Pacey S, Feng X, Johnston A, Bomalaski J, Moir G, Lau K, Ellis S, Sheaff M. Expansion Phase 1 Study of Pegargiminase Plus Pemetrexed and Cisplatin in Patients With Argininosuccinate Synthetase 1-Deficient Mesothelioma: Safety, Efficacy, and Resistance Mechanisms. Jto Clinical and Research Reports. 1: 100093. PMID 34589965 DOI: 10.1016/j.jtocrr.2020.100093  0.201
2017 Josephs DH, Bax HJ, Dodev T, Georgouli M, Nakamura M, Pellizzari G, Saul L, Karagiannis P, Cheung A, Herraiz C, Ilieva KM, Correa I, Fittall M, Crescioli S, Gazinska P, ... ... Spicer J, et al. Anti-folate receptor-α IgE but not IgG recruits macrophages to attack tumors via TNF-α/MCP-1 signaling. Cancer Research. PMID 28096174 DOI: 10.1158/0008-5472.CAN-16-1829  0.198
2014 Josephs DH, Spicer JF, Karagiannis P, Gould HJ, Karagiannis SN. IgE immunotherapy: a novel concept with promise for the treatment of cancer. Mabs. 6: 54-72. PMID 24423620 DOI: 10.4161/mabs.27029  0.196
2023 Chauhan J, Grandits M, Palhares LCGF, Mele S, Nakamura M, López-Abente J, Crescioli S, Laddach R, Romero-Clavijo P, Cheung A, Stavraka C, Chenoweth AM, Sow HS, Chiaruttini G, Gilbert AE, ... ... Spicer J, et al. Anti-cancer pro-inflammatory effects of an IgE antibody targeting the melanoma-associated antigen chondroitin sulfate proteoglycan 4. Nature Communications. 14: 2192. PMID 37185332 DOI: 10.1038/s41467-023-37811-3  0.194
2022 Hughes DJ, Subesinghe M, Taylor B, Bille A, Spicer J, Papa S, Goh V, Cook GJR. F FDG PET/CT and Novel Molecular Imaging for Directing Immunotherapy in Cancer. Radiology. 212481. PMID 35762888 DOI: 10.1148/radiol.212481  0.191
2012 Karagiannis SN, Josephs DH, Karagiannis P, Gilbert AE, Saul L, Rudman SM, Dodev T, Koers A, Blower PJ, Corrigan C, Beavil AJ, Spicer JF, Nestle FO, Gould HJ. Recombinant IgE antibodies for passive immunotherapy of solid tumours: from concept towards clinical application. Cancer Immunology, Immunotherapy : Cii. 61: 1547-64. PMID 22139135 DOI: 10.1007/s00262-011-1162-8  0.189
2018 Cheung A, Opzoomer JW, Ilieva KM, Gazinska P, Hoffmann RM, Mirza H, Marlow R, Francesch-Domenech E, Fittall MW, Dominguez Rodriguez D, Clifford A, Badder L, Patel N, Mele S, Pellizzari G, ... ... Spicer J, et al. Anti-Folate Receptor alpha-directed Antibody Therapies Restrict the Growth of Triple Negative Breast Cancer. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 30068707 DOI: 10.1158/1078-0432.CCR-18-0652  0.187
2013 Simon ST, Higginson IJ, Benalia H, Gysels M, Murtagh FE, Spicer J, Bausewein C. Episodic and continuous breathlessness: a new categorization of breathlessness. Journal of Pain and Symptom Management. 45: 1019-29. PMID 23017608 DOI: 10.1016/J.Jpainsymman.2012.06.008  0.184
2015 Karagiannis P, Villanova F, Josephs DH, Correa I, Van Hemelrijck M, Hobbs C, Saul L, Egbuniwe IU, Tosi I, Ilieva KM, Kent E, Calonje E, Harries M, Fentiman I, Taylor-Papadimitriou J, ... ... Spicer JF, et al. Elevated IgG4 in patient circulation is associated with the risk of disease progression in melanoma. Oncoimmunology. 4: e1032492. PMID 26451312 DOI: 10.1080/2162402X.2015.1032492  0.183
2021 Willsmore ZN, Coumbe BGT, Crescioli S, Reci S, Gupta A, Harris RJ, Chenoweth A, Chauhan J, Bax HJ, McCraw A, Cheung A, Osborn G, Hoffmann RM, Nakamura M, Laddach R, ... ... Spicer JF, et al. Combined anti-PD-1 and anti-CTLA-4 checkpoint blockade: treatment of melanoma and immune mechanisms of action. European Journal of Immunology. PMID 33450785 DOI: 10.1002/eji.202048747  0.18
2020 Chauhan J, McCraw AJ, Nakamura M, Osborn G, Sow HS, Cox VF, Stavraka C, Josephs DH, Spicer JF, Karagiannis SN, Bax HJ. IgE Antibodies against Cancer: Efficacy and Safety. Antibodies (Basel, Switzerland). 9. PMID 33081206 DOI: 10.3390/antib9040055  0.177
2020 Nakamura M, Souri EA, Osborn G, Laddach R, Chauhan J, Stavraka C, Lombardi S, Black A, Khiabany A, Khair DO, Figini M, Winship A, Ghosh S, Montes A, Spicer JF, et al. IgE Activates Monocytes from Cancer Patients to Acquire a Pro-Inflammatory Phenotype. Cancers. 12. PMID 33203088 DOI: 10.3390/cancers12113376  0.175
2023 Papa S, Adami A, Metoudi M, Beatson R, George MS, Achkova D, Williams E, Arif S, Reid F, Elstad M, Beckley-Hoelscher N, Douri A, Delord M, Lyne M, Shivapatham D, ... ... Spicer J, et al. Intratumoral pan-ErbB targeted CAR-T for head and neck squamous cell carcinoma: interim analysis of the T4 immunotherapy study. Journal For Immunotherapy of Cancer. 11. PMID 37321663 DOI: 10.1136/jitc-2023-007162  0.175
2019 Opzoomer JW, Sosnowska D, Anstee JE, Spicer JF, Arnold JN. Cytotoxic Chemotherapy as an Immune Stimulus: A Molecular Perspective on Turning Up the Immunological Heat on Cancer. Frontiers in Immunology. 10: 1654. PMID 31379850 DOI: 10.3389/fimmu.2019.01654  0.174
2016 Thayaparan T, Spicer JF, Maher J. The role of the HGF/Met axis in mesothelioma. Biochemical Society Transactions. 44: 363-70. PMID 27068941 DOI: 10.1042/Bst20150252  0.174
2020 Willsmore ZN, Harris RJ, Crescioli S, Hussein K, Kakkassery H, Thapa D, Cheung A, Chauhan J, Bax HJ, Chenoweth A, Laddach R, Osborn G, McCraw A, Hoffmann RM, Nakamura M, ... ... Spicer JF, et al. B Cells in Patients With Melanoma: Implications for Treatment With Checkpoint Inhibitor Antibodies. Frontiers in Immunology. 11: 622442. PMID 33569063 DOI: 10.3389/fimmu.2020.622442  0.173
2021 Roulstone V, Mansfield D, Harris RJ, Twigger K, White C, de Bono J, Spicer J, Karagiannis SN, Vile R, Pandha H, Melcher A, Harrington K. Antiviral antibody responses to systemic administration of an oncolytic RNA virus: the impact of standard concomitant anticancer chemotherapies. Journal For Immunotherapy of Cancer. 9. PMID 34301814 DOI: 10.1136/jitc-2021-002673  0.168
2018 Crescioli S, Chiaruttini G, Mele S, Ilieva KM, Pellizzari G, Spencer DIR, Gardner RA, Lacy KE, Spicer JF, Tutt ANJ, Wagner GK, Karagiannis SN. Engineering and stable production of recombinant IgE for cancer immunotherapy and AllergoOncology. The Journal of Allergy and Clinical Immunology. PMID 29360527 DOI: 10.1016/J.Jaci.2017.12.986  0.168
2015 Josephs DH, Bax HJ, Lentfer H, Selkirk C, Spicer JF, Karagiannis SN. Potential for monocyte recruitment by IgE immunotherapy for cancer in a rat model of tumour metastasis. Lancet (London, England). 385: S53. PMID 26312875 DOI: 10.1016/S0140-6736(15)60368-3  0.168
2020 Hoffmann RM, Crescioli S, Mele S, Sachouli E, Cheung A, Chui CK, Andriollo P, Jackson PJM, Lacy KE, Spicer JF, Thurston DE, Karagiannis SN. A Novel Antibody-Drug Conjugate (ADC) Delivering a DNA Mono-Alkylating Payload to Chondroitin Sulfate Proteoglycan (CSPG4)-Expressing Melanoma. Cancers. 12. PMID 32331483 DOI: 10.3390/Cancers12041029  0.166
2017 Ilieva KM, Fazekas-Singer J, Achkova DY, Dodev TS, Mele S, Crescioli S, Bax HJ, Cheung A, Karagiannis P, Correa I, Figini M, Marlow R, Josephs DH, Beavil AJ, Maher J, ... Spicer JF, et al. Functionally Active Fc Mutant Antibodies Recognizing Cancer Antigens Generated Rapidly at High Yields. Frontiers in Immunology. 8: 1112. PMID 28959256 DOI: 10.3389/Fimmu.2017.01112  0.164
2021 Osborn G, Stavraka C, Adams R, Sayasneh A, Ghosh S, Montes A, Lacy KE, Kristeleit R, Spicer J, Josephs DH, Arnold JN, Karagiannis SN. Macrophages in ovarian cancer and their interactions with monoclonal antibody therapies. Clinical and Experimental Immunology. PMID 35020853 DOI: 10.1093/cei/uxab020  0.163
2017 Klampatsa A, Achkova DY, Davies DM, Parente-Pereira AC, Woodman N, Rosekilly J, Osborne G, Thayaparan T, Bille A, Sheaf M, Spicer JF, King J, Maher J. Intracavitary 'T4 immunotherapy' of malignant mesothelioma using pan-ErbB re-targeted CAR T-cells. Cancer Letters. PMID 28223167 DOI: 10.1016/J.Canlet.2017.02.015  0.161
2021 Harris RJ, Cheung A, Ng JCF, Laddach R, Chenoweth AM, Crescioli S, Fittall M, Dominguez Rodriguez D, Roberts J, Levi D, Liu F, Alberts E, Quist J, Santaolalla A, Pinder SE, ... ... Spicer JF, et al. Tumor-Infiltrating B Lymphocyte Profiling Identifies IgG-Biased, Clonally Expanded Prognostic Phenotypes In Triple-Negative Breast Cancer. Cancer Research. PMID 34224371 DOI: 10.1158/0008-5472.CAN-20-3773  0.158
2023 Crescioli S, Correa I, Ng J, Willsmore ZN, Laddach R, Chenoweth A, Chauhan J, Di Meo A, Stewart A, Kalliolia E, Alberts E, Adams R, Harris RJ, Mele S, Pellizzari G, ... ... Spicer J, et al. B cell profiles, antibody repertoire and reactivity reveal dysregulated responses with autoimmune features in melanoma. Nature Communications. 14: 3378. PMID 37291228 DOI: 10.1038/s41467-023-39042-y  0.157
2018 Hoffmann RM, Coumbe BGT, Josephs DH, Mele S, Ilieva KM, Cheung A, Tutt AN, Spicer JF, Thurston DE, Crescioli S, Karagiannis SN. Antibody structure and engineering considerations for the design and function of Antibody Drug Conjugates (ADCs). Oncoimmunology. 7: e1395127. PMID 29375935 DOI: 10.1080/2162402X.2017.1395127  0.157
2021 Karagiannis P, Correa I, Chauhan J, Cheung A, Dominguez-Rodriguez D, Terranova Barberio M, Harris RJ, Crescioli S, Spicer J, Bokemeyer C, Lacy KE, Karagiannis SN. Innate stimulation of B cells ex vivo enhances antibody secretion and identifies tumour-reactive antibodies from cancer patients. Clinical and Experimental Immunology. PMID 35020866 DOI: 10.1093/cei/uxab005  0.147
2020 Williams IP, Crescioli S, Sow HS, Bax HJ, Hobbs C, Ilieva KM, French E, Pellizzari G, Cox V, Josephs DH, Spicer JF, Karagiannis SN, Mele S. safety profile of a CSPG4-directed IgE antibody in an immunocompetent rat model. Mabs. 12: 1685349. PMID 31769737 DOI: 10.1080/19420862.2019.1685349  0.137
2010 Wilkie S, Burbridge SE, Chiapero-Stanke L, Pereira AC, Cleary S, van der Stegen SJ, Spicer JF, Davies DM, Maher J. Selective expansion of chimeric antigen receptor-targeted T-cells with potent effector function using interleukin-4. The Journal of Biological Chemistry. 285: 25538-44. PMID 20562098 DOI: 10.1074/Jbc.M110.127951  0.134
2023 Dillon MT, Guevara J, Mohammed K, Patin EC, Smith SA, Dean E, Jones GN, Willis SE, Petrone M, Silva C, Thway K, Bunce C, Roxanis I, Nenclares P, Wilkins A, ... ... Spicer J, et al. Durable responses to ATR inhibition with ceralasertib in tumors with genomic defects and high inflammation. The Journal of Clinical Investigation. PMID 37934611 DOI: 10.1172/JCI175369  0.132
2023 Homicsko K, Zygoura P, Norkin M, Tissot S, Shakarishvili N, Popat S, Curioni-Fontecedro A, O'Brien M, Pope A, Shah R, Fisher P, Spicer J, Roy A, Gilligan D, Rusakiewicz S, et al. PD-1-expressing macrophages and CD8 T cells are independent predictors of clinical benefit from PD-1 inhibition in advanced mesothelioma. Journal For Immunotherapy of Cancer. 11. PMID 37880184 DOI: 10.1136/jitc-2023-007585  0.13
2014 Saul L, Josephs DH, Cutler K, Bradwell A, Karagiannis P, Selkirk C, Gould HJ, Jones P, Spicer JF, Karagiannis SN. Comparative reactivity of human IgE to cynomolgus monkey and human effector cells and effects on IgE effector cell potency. Mabs. 6: 509-22. PMID 24492303 DOI: 10.4161/mabs.27828  0.126
2011 Rudman SM, Jameson MB, McKeage MJ, Savage P, Jodrell DI, Harries M, Acton G, Erlandsson F, Spicer JF. A phase 1 study of AS1409, a novel antibody-cytokine fusion protein, in patients with malignant melanoma or renal cell carcinoma. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 17: 1998-2005. PMID 21447719 DOI: 10.1158/1078-0432.CCR-10-2490  0.124
2022 Harris RJ, Willsmore Z, Laddach R, Crescioli S, Chauhan J, Cheung A, Black A, Geh JLC, MacKenzie Ross AD, Healy C, Tsoka S, Spicer J, Lacy KE, Karagiannis SN. Enriched circulating and tumor-resident TGF-β regulatory B cells in patients with melanoma promote FOXP3 Tregs. Oncoimmunology. 11: 2104426. PMID 35909944 DOI: 10.1080/2162402X.2022.2104426  0.122
1998 SPICER JB, WALLACE SL. Journal of Materials Science. 33: 3899-3906. DOI: 10.1023/A:1004680209200  0.12
2018 Correa I, Ilieva KM, Crescioli S, Lombardi S, Figini M, Cheung A, Spicer JF, Tutt ANJ, Nestle FO, Karagiannis P, Lacy KE, Karagiannis SN. Evaluation of Antigen-Conjugated Fluorescent Beads to Identify Antigen-Specific B Cells. Frontiers in Immunology. 9: 493. PMID 29628923 DOI: 10.3389/fimmu.2018.00493  0.119
2021 Man F, Koers A, Karagiannis P, Josephs DH, Bax HJ, Gilbert AE, Dodev TS, Mele S, Chiarruttini G, Crescioli S, Chauhan J, Blower JE, Cooper MS, Spicer J, Karagiannis SN, et al. trafficking of a tumor-targeting IgE antibody: molecular imaging demonstrates rapid hepatobiliary clearance compared to IgG counterpart. Oncoimmunology. 10: 1966970. PMID 34513315 DOI: 10.1080/2162402X.2021.1966970  0.118
2016 Saul L, Ilieva KM, Bax HJ, Karagiannis P, Correa I, Rodriguez-Hernandez I, Josephs DH, Tosi I, Egbuniwe IU, Lombardi S, Crescioli S, Hobbs C, Villanova F, Cheung A, Geh JL, ... ... Spicer JF, et al. IgG subclass switching and clonal expansion in cutaneous melanoma and normal skin. Scientific Reports. 6: 29736. PMID 27411958 DOI: 10.1038/Srep29736  0.113
2019 Pellizzari G, Hoskin C, Crescioli S, Mele S, Gotovina J, Chiaruttini G, Bianchini R, Ilieva K, Bax HJ, Papa S, Lacy KE, Jensen-Jarolim E, Tsoka S, Josephs DH, Spicer JF, et al. IgE re-programs alternatively-activated human macrophages towards pro-inflammatory anti-tumoural states. Ebiomedicine. PMID 30956175 DOI: 10.1016/j.ebiom.2019.03.080  0.11
2021 Peng C, Chen M, Spicer JB, Jiang X. Acoustics at the nanoscale (nanoacoustics): A comprehensive literature review.: Part II: Nanoacoustics for biomedical imaging and therapy. Sensors and Actuators. a, Physical. 332. PMID 34937992 DOI: 10.1016/j.sna.2021.112925  0.081
2019 Ilieva KM, Fazekas-Singer J, Bax HJ, Crescioli S, Montero-Morales L, Mele S, Sow HS, Stavraka C, Josephs DH, Spicer JF, Steinkellner H, Jensen-Jarolim E, Tutt ANJ, Karagiannis SN. AllergoOncology: Expression platform development and functional profiling of an anti-HER2 IgE antibody. Allergy. PMID 30964550 DOI: 10.1111/all.13818  0.08
2016 Vigor K, Emerson J, Scott R, Cheek J, Barton C, Bax HJ, Josephs DH, Karagiannis SN, Spicer JF, Lentfer H. Development of Downstream Processing to Minimise Beta-Glucan Impurities in GMP-Manufactured Therapeutic Antibodies. Biotechnology Progress. PMID 27604040 DOI: 10.1002/btpr.2359  0.077
2015 Brupbacher MC, Zhang D, Buchta WM, Rhim YR, Nagle DC, Spicer JB. Post-treatment of Plasma-Sprayed Cr2O3 with Methane-Containing Gas for Conversion to Binder-Free Cr3C2 Journal of Thermal Spray Technology. 24: 1513-1519. DOI: 10.1007/s11666-015-0348-6  0.061
2003 Spicer JB, Dagdigian P, Osiander R, Miragliotta J, Zhang XC, Kersting R, Crosley D, Hanson R, Jeffries J. Overview: MURI Center on spectroscopic and time domain detection of trace explosives in condensed and vapor phases Proceedings of Spie - the International Society For Optical Engineering. 5089: 1088-1094. DOI: 10.1117/12.487531  0.061
2016 Barton C, Vigor K, Scott R, Jones P, Lentfer H, Bax HJ, Josephs DH, Karagiannis SN, Spicer JF. Beta-glucan contamination of pharmaceutical products: How much should we accept? Cancer Immunology, Immunotherapy : Cii. PMID 27473075 DOI: 10.1007/s00262-016-1875-9  0.056
2021 Peng C, Chen M, Spicer JB, Jiang X. Acoustics at the nanoscale (nanoacoustics): A comprehensive literature review.: Part I: Materials, devices and selected applications. Sensors and Actuators. a, Physical. 332. PMID 34937991 DOI: 10.1016/j.sna.2021.112719  0.053
2005 Dodson C, Fitch MJ, Osiander R, Spicer JB. Terahertz imaging for anti-personnel mine detection Proceedings of Spie - the International Society For Optical Engineering. 5790: 85-93. DOI: 10.1117/12.604751  0.048
1987 Wagner JW, Spicer JB. Theoretical noise-limited sensitivity of classical interferometry Journal of the Optical Society of America B: Optical Physics. 4: 1316-1326. DOI: 10.1364/JOSAB.4.001316  0.047
2008 OSIANDER R, FITCH MJ, LEAHY-HOPPA M, DIKMELIK Y, SPICER JB. SIGNATURE AND SIGNAL GENERATION ASPECTS OF EXPLOSIVE DETECTION USING TERAHERTZ TIME-DOMAIN SPECTROSCOPY International Journal of High Speed Electronics and Systems. 18: 295-306. DOI: 10.1142/S0129156408005357  0.043
2007 McEnnis C, Dikmelik Y, Spicer JB. Femtosecond laser-induced fragmentation and cluster formation studies of solid phase trinitrotoluene using time-of-flight mass spectrometry Applied Surface Science. 254: 557-562. DOI: 10.1016/J.APSUSC.2007.06.053  0.043
1996 Ehrlich MJ, Murray TW, Wagner JW, Baldwin KC, Spicer JB. Laser ultrasonics for process control: Issues for implementation Proceedings of Spie - the International Society For Optical Engineering. 2948: 50-61. DOI: 10.1117/12.259213  0.042
2001 Champion JL, Spicer JB, Osiander R, Spicer JWM. Shearographic monitoring of time-dependent thermoelastic deformations Research in Nondestructive Evaluation. 13: 173-187.  0.041
2020 Peters AB, Hernandez A, Zhang D, Brupbacher MC, Nagle DC, McGuiggan PM, Mueller T, Spicer JB. A Reaction Synthesis Approach to Additively Manufacture Net-Shape Chromium Carbide and Non-Oxide Refractory Ceramics Additive Manufacturing. 34: 101186. DOI: 10.1016/j.addma.2020.101186  0.038
2017 Zeng FW, Contescu CI, Gallego NC, Spicer JB. Theory and application of laser ultrasonic shear wave birefringence measurements to the determination of microstructure orientation in transversely isotropic, polycrystalline graphite materials Carbon. 115: 460-470. DOI: 10.1016/J.Carbon.2016.12.042  0.037
2014 Spicer JB, Zeng FW, Han K, Olasov LR, Gallego NC, Contescu CI. Effects of graphite porosity and anisotropy on measurements of elastic modulus using laser ultrasonics Ieee International Ultrasonics Symposium, Ius. 232-235. DOI: 10.1109/ULTSYM.2014.0059  0.037
2015 Zeng FW, Han K, Olasov LR, Gallego NC, Contescu CI, Spicer JB. Characterization of nuclear graphite elastic properties using laser ultrasonic methods Proceedings of Spie - the International Society For Optical Engineering. 9485. DOI: 10.1117/12.2176885  0.035
2013 Spicer JB, Lindamood LR. Studies of texture in nuclear graphites using laser ultrasonic line source measurements Proceedings of Spie - the International Society For Optical Engineering. 8695. DOI: 10.1117/12.2009774  0.035
2019 Jiang X, Spicer JB. Nanoacoustics Comes Quietly [Guest Editorial] Ieee Nanotechnology Magazine. 13: 4-4. DOI: 10.1109/Mnano.2019.2904771  0.035
2012 Spicer JB, Wagner JW. Absolute calibration of interferometric systems for detection and measurement of surface acoustic waves. Applied Optics. 27: 3561-6. PMID 20539416 DOI: 10.1364/AO.27.003561  0.035
2017 Brupbacher MC, Zhang D, Buchta WM, Airola MB, Brown DM, Thomas ME, Spicer JB. Temperature-dependent diffuse reflectance spectroscopy of plasma-sprayed Cr-doped α-alumina using supercontinuum laser illumination and CO2 laser heating. Applied Optics. 56: 7618-7628. PMID 29047739  0.033
2003 Richardson CJK, Spicer JB. Characterization of heat-treated tungsten thin films using picosecond duration thermoelastic transients Optics and Lasers in Engineering. 40: 379-391. DOI: 10.1016/S0143-8166(02)00090-8  0.033
2019 Olasov LR, Zeng FW, Spicer JB, Gallego NC, Contescu CI. Modeling the effects of oxidation-induced porosity on the elastic moduli of nuclear graphites Carbon. 141: 304-315. DOI: 10.1016/J.Carbon.2018.09.051  0.032
2008 Dikmelik Y, McEnnis C, Spicer JB. Femtosecond and nanosecond laser-induced breakdown spectroscopy of trinitrotoluene. Optics Express. 16: 5332-7. PMID 18542635  0.032
2016 Spicer JB, Olasov LR, Zeng FW, Han K, Gallego NC, Contescu CI. Laser ultrasonic assessment of the effects of porosity and microcracking on the elastic moduli of nuclear graphites Journal of Nuclear Materials. 471: 80-91. DOI: 10.1016/J.Jnucmat.2015.12.015  0.032
2018 Brupbacher MC, Zhang D, Buchta WM, Montalbano TJ, Caruso KS, Airola MB, Brown DM, Thomas ME, Spicer JB. Experimental characterization and physics-based modeling of the temperature-dependent diffuse reflectance of plasma-sprayed NdZrO in the near to short-wave infrared. Applied Optics. 57: 7782-7792. PMID 30462042  0.03
2011 Balogun O, Cole GD, Huber R, Chinn D, Murray TW, Spicer JB. High-spatial-resolution sub-surface imaging using a laser-based acoustic microscopy technique. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 58: 226-33. PMID 21244990 DOI: 10.1109/Tuffc.2011.1789  0.029
2002 Matsuda Y, Richardson CJ, Spicer JB. Narrowband generation of ultrafast acoustic and thermal transients in thin films for enhanced detectability. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 49: 915-21. PMID 12152945 DOI: 10.1109/TUFFC.2002.1020161  0.028
2009 Channels L, Chakraborty D, Butrym B, Kovvali N, Spicer J, Papandreou-Suppappola A, Afshari M, Inman D, Chattopadhyay A. A comparative study of fatigue damage sensing in aluminum alloys using electrical impedance and laser ultrasonic methods Proceedings of Spie - the International Society For Optical Engineering. 7295. DOI: 10.1117/12.815980  0.028
2008 Channels L, Chakraborty D, Simon D, Kovvali N, Spicer J, Papandreou-Suppappola A, Cochran D, Peralta P, Chattopadhyay A. Ultrasonic sensing and time-frequency analysis for detecting plastic deformation in an aluminum plate Proceedings of Spie - the International Society For Optical Engineering. 6926. DOI: 10.1117/12.776625  0.027
2012 McKie AD, Wagner JW, Spicer JB, Deaton JB. Dual-beam interferometer for the accurate determination of surface-wave velocity. Applied Optics. 30: 4034-9. PMID 20706500 DOI: 10.1364/AO.30.004034  0.027
1996 Wagner JW, Spicer JB, Murray T, Hurley D, Ehrlich M. Fundamental issues for optimization of laser sources for generation of ultrasound The Journal of the Acoustical Society of America. 100: 2622-2622. DOI: 10.1121/1.417699  0.027
1998 Hurley DH, Spicer JB. Laser-generated ultrasound in single-crystal Mindlin-type plates: Theory and experiment Journal of Engineering and Applied Science. 36: 987-994.  0.027
2009 Balogun O, Huber R, Chinn D, Spicer JB. Laser ultrasonic inspection of the microstructural state of thin metal foils. The Journal of the Acoustical Society of America. 125: 1437-43. PMID 19275301 DOI: 10.1121/1.3068447  0.026
2001 Blodgett DW, Spicer JB. Sub-micron elastic property characterization of materials using a near-field scanning optical microscope Proceedings of Spie - the International Society For Optical Engineering. 4456: 97-106. DOI: 10.1117/12.449527  0.026
2000 Richardson CJK, Wisnioski MH, Spicer JB, Demaree JD, Cole MW, Hubbard CW, Joshi PC, Hirvonen JK, Kim H, Pique A, Chrisey DB. Optimization of The Processing Parameters for Pulsed Laser Deposition of Nickel Silicide Ohmic Contacts On SiC Mrs Proceedings. 617. DOI: 10.1557/PROC-617-J7.4  0.026
2013 Spicer JB. Effects of the nonlinear elastic behavior of bicycle chain on transmission efficiency Journal of Applied Mechanics, Transactions Asme. 80. DOI: 10.1115/1.4007431  0.026
1998 Hurley DH, Spicer JB, Wagner JW, Murray TW. Investigation of the anisotropic nature of laser-generated ultrasound in zinc and unidirectional carbon epoxy composites Ultrasonics. 36: 355-360. DOI: 10.1007/978-1-4615-5947-4_63  0.026
2001 Richardson CJ, Spicer JB, Huber RD, Lee HW. Direct detection of ultrafast thermal transients by use of a chirped, supercontinuum white-light pulse. Optics Letters. 26: 1105-7. PMID 18049534 DOI: 10.1364/OL.26.001105  0.025
1999 Di Scalea FL, Berndt TP, Spicer JB, Djordjevic BB. Remote laser generation of narrow-band surface waves through optical fibers. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 46: 1551-7. PMID 18244353 DOI: 10.1109/58.808880  0.025
2018 Zeng FW, Zhang D, Spicer JB. Palladium nanoparticle formation processes in fluoropolymers by thermal decomposition of organometallic precursors. Physical Chemistry Chemical Physics : Pccp. 20: 24389-24398. PMID 30221271 DOI: 10.1039/c8cp04997a  0.024
1996 Spicer JB, Hurley DH. Epicentral and near epicenter surface displacements on pulsed laser irradiated metallic surfaces Applied Physics Letters. 68: 3561-3563. DOI: 10.1063/1.116637  0.024
2012 Hurley DH, Spicer JB. An investigation of the effects of material anisotropy and heterogeneity on pulsed, laser-generated acoustic signals. Ieee Transactions On Ultrasonics, Ferroelectrics, and Frequency Control. 46: 1387-95. PMID 18244334 DOI: 10.1109/58.808861  0.023
2016 Spicer JB, Zeng FW. Line source representations for shear wave birefringence measurements in transversely isotropic materials using laser ultrasonics Wave Motion. 61: 1-10. DOI: 10.1016/j.wavemoti.2015.10.003  0.023
2005 See KC, Spicer JB, Brupbacher J, Zhang D, Vargo TG. Modeling interband transitions in silver nanoparticle-fluoropolymer composites. The Journal of Physical Chemistry. B. 109: 2693-8. PMID 16851276 DOI: 10.1021/jp046687h  0.023
2017 Spicer JB, Zeng FW, Olasov LR. Subsurface, thermoelastic line source excitation of a transversely isotropic half space Wave Motion. 72: 87-100. DOI: 10.1016/J.WAVEMOTI.2016.12.004  0.023
2015 Brupbacher MC, Zhang D, Buchta WM, Graybeal ML, Rhim YR, Nagle DC, Spicer JB. Synthesis and characterization of binder-free Cr3C2 coatings on nickel-based alloys for molten fluoride salt corrosion resistance Journal of Nuclear Materials. 461: 215-220. DOI: 10.1016/j.jnucmat.2015.03.017  0.023
2018 Guo Q, Bishop CJ, Meyer RA, Wilson DR, Olasov L, Schlesinger DE, Mather PT, Spicer JB, Elisseeff JH, Green JJ. Entanglement-Based Thermoplastic Shape Memory Polymeric Particles with Photothermal Actuation for Biomedical Applications. Acs Applied Materials & Interfaces. PMID 29600843 DOI: 10.1021/Acsami.8B01582  0.022
2012 Wagner JW, Deaton JB, Spicer JB. Generation of ultrasound by repetitively Q-switching a pulsed Nd:YAG laser. Applied Optics. 27: 4696-700. PMID 20539637 DOI: 10.1364/AO.27.004696  0.022
2001 Wetsel GC, Farahi RH, Richardson CJK, Spicer JB. Approach interactions of scanned probes in dynamic pecking mode Applied Physics Letters. 79: 2657-2659. DOI: 10.1063/1.1410334  0.022
1999 Spicer JB, Richardson CJK, Ehrlich MJ, Bernstein JR, Fukuda M, Terada M. Effects of Frictional Loss on Bicycle Chain Drive Efficiency Journal of Mechanical Design. 123: 598-605. DOI: 10.1115/1.1412848  0.022
2004 Hurley DH, Spicer JB. Line source representation for laser-generated ultrasound in an elastic transversely isotropic half-space The Journal of the Acoustical Society of America. 116: 2914-2922. DOI: 10.1121/1.1791721  0.02
2006 Dikmelik Y, Spicer JB, Fitch MJ, Osiander R. Effects of surface roughness on reflection spectra obtained by terahertz time-domain spectroscopy. Optics Letters. 31: 3653-5. PMID 17130934 DOI: 10.1364/Ol.31.003653  0.02
2008 Spicer JB, Dikmelik Y. Dynamic effects in nonlinearly coupled elastic deformation and diffusion fields in solids Journal of Applied Physics. 104: 023528. DOI: 10.1063/1.2956743  0.019
2010 Leahy-Hoppa MR, Miragliotta J, Osiander R, Burnett J, Dikmelik Y, McEnnis C, Spicer JB. Ultrafast laser-based spectroscopy and sensing: applications in LIBS, CARS, and THz spectroscopy. Sensors (Basel, Switzerland). 10: 4342-72. PMID 22399883 DOI: 10.3390/s100504342  0.019
2019 Brupbacher MC, Zhang D, Buchta WM, Airola MB, Brown DM, Thomas ME, Spicer JB. Supercontinuum-laser diffuse reflectance spectroscopy in conjunction with an extended Kubelka-Munk model-a methodology for determination of temperature-dependent quantum efficiency in highly scattering and fluorescent media. Applied Optics. 58: 2438-2445. PMID 31045035 DOI: 10.1364/AO.58.002438  0.018
1986 Wetsel Jr. GC, Spicer JB. Nonlinear effects in photothermal-optical-beam-deflection imaging Canadian Journal of Physics. 64: 1269-1275. DOI: 10.1139/p86-219  0.018
2014 Dejournett TJ, Spicer JB. Photoinduced silver precursor decomposition for particle modification in tungsten oxide-polymer matrix nanocomposites Journal of Physical Chemistry C. 118: 9820-9831. DOI: 10.1021/Jp5015324  0.018
2016 Spicer JB, Zeng FW. Corrigendum to "Line source representations for shear wave birefringence measurements in transversely isotropic materials using laser ultrasonics" [Wave Motion 61 (2016) 1-10] Wave Motion. DOI: 10.1016/j.wavemoti.2016.02.008  0.017
2021 Peters AB, Zhang D, Hernandez A, Brupbacher MC, Nagle DC, Mueller T, Spicer JB. Selective laser sintering in reactive atmospheres: Towards in-situ synthesis of net-shaped carbide and nitride ceramics Additive Manufacturing. 45: 102052. DOI: 10.1016/J.ADDMA.2021.102052  0.016
1990 Wagner JW, McKie ADW, Spicer JB, Deaton JB. Modulated laser array sources for generation of narrowband and directed ultrasound Journal of Nondestructive Evaluation. 9: 263-270. DOI: 10.1007/BF00565644  0.016
1996 Huber RD, Chinn DJ, Candy JV, Thomas GH, Spicer JB. Enhancement of laser‐based ultrasonic wave detection through signal processing techniques The Journal of the Acoustical Society of America. 100: 2623-2623. DOI: 10.1121/1.417700  0.015
2000 di Scalea FL, Spicer JB, Green RE. Electronic Shearography with Thermal Loading for Detecting Debonds in Thick Polyurethane/Steel Panels for Marine Applications Research in Nondestructive Evaluation. 12: 43-51. DOI: 10.1080/09349840009409648  0.015
2014 Dejournett TJ, Spicer JB. The influence of oxygen on the microstructural, optical and photochromic properties of polymer-matrix, tungsten-oxide nanocomposite films Solar Energy Materials and Solar Cells. 120: 102-108. DOI: 10.1016/J.Solmat.2013.08.023  0.015
2002 Richardson CJK, Spicer JB. Short-time thermoelastic contributions to picosecond-time scale reflectivity measurements of metals Applied Physics Letters. 80: 2895-2897. DOI: 10.1063/1.1472464  0.015
1999 Blodgett DW, Spicer JB. Detection of ultrasound using an apertureless near-field scanning optical microscope Applied Physics Letters. 74: 3735-3737. DOI: 10.1063/1.123237  0.015
2013 DeJournett TJ, Spicer JB. Laser-induced, in situ, nanoparticle shell synthesis in polymer matrix nanocomposites. Physical Chemistry Chemical Physics : Pccp. 15: 19753-62. PMID 24141532 DOI: 10.1039/C3Cp53572J  0.014
2019 Peters AB, Zhang D, Brupbacher MC, Hernandez A, Nagle DC, Mueller T, Spicer JB. Isovolumetric synthesis of chromium carbide for selective laser reaction sintering (SLRS) International Journal of Refractory Metals and Hard Materials. 83: 104967. DOI: 10.1016/J.IJRMHM.2019.05.013  0.014
2002 Bernstein JR, Spicer JB. Hybrid laser/broadband EMAT ultrasonic system for characterizing cracks in metals. The Journal of the Acoustical Society of America. 111: 1685-91. PMID 12002851 DOI: 10.1121/1.1462640  0.014
1996 Candy JV, Thomas GH, Chinn D, Spicer JB. Model reference signal processing for a laser ultrasonics experiment. The Journal of the Acoustical Society of America. 99: 2497-2500. DOI: 10.1121/1.415651  0.013
2001 Champion JL, Spicer JB, Osiander R, Spicer JWM. Shearographic Monitoring of Time-Dependent Thermoelastic Deformations Research in Nondestructive Evaluation. 13: 173-187. DOI: 10.1080/09349840109409696  0.013
2007 Spicer JB, See KC, Zhang D, Katsumi Y, Brupbacher J, Vargo TG. Linear and nonlinear optical behavior of palladium nanoparticle reinforced fluoropolymer composites Chemical Physics Letters. 445: 246-250. DOI: 10.1016/j.cplett.2007.07.087  0.013
1990 Deaton JB, McKie ADW, Spicer JB, Wagner JW. Generation of narrow‐band ultrasound with a long cavity mode‐locked Nd:YAG laser Applied Physics Letters. 56: 2390-2392. DOI: 10.1063/1.102925  0.013
1997 Hurley D, Spicer J, Conant R, Telschow K. Determination of the optical absorption coefficient via analysis of laser-generated plate waves Ieee Transactions On Ultrasonics, Ferroelectrics and Frequency Control. 44: 902-908. DOI: 10.1109/58.655205  0.013
2008 Spicer JB. Nonlinear effects on impurity segregation in edge dislocation strain fields Scripta Materialia. 59: 377-380. DOI: 10.1016/j.scriptamat.2008.01.061  0.013
2015 Dejournett TJ, Han K, Olasov LR, Zeng FW, Lee B, Spicer JB. Linear and nonlinear optical processing of polymer matrix nanocomposites Proceedings of Spie - the International Society For Optical Engineering. 9556. DOI: 10.1117/12.2187113  0.012
2012 DeJournett TJ, Spicer JB. Synthesis and patterning of polymer matrix nanocomposites using femtosecond laser-assisted processing Materials Research Society Symposium Proceedings. 1455: 43-54. DOI: 10.1557/Opl.2012.1297  0.012
1991 Wagner JW, Spicer JB, Deaton JB. The generation of narrow‐band and directed ultrasound using spatially and temporally modulated arrays The Journal of the Acoustical Society of America. 89: 1909-1909. DOI: 10.1121/1.2029466  0.011
1995 Spicer JB. Laser ultrasonic monitoring of steel microstructure at elevated temperatures The Journal of the Acoustical Society of America. 97: 3372-3372. DOI: 10.1121/1.412658  0.01
2021 Ma J, Hu X, Li C, Wirth B, Thomas M, Spicer J. Interpretation of optical absorption loss measurements in synthetic sapphire using positron annihilation lifetime spectroscopy Optical Materials Express. 11: 1656. DOI: 10.1364/OME.417473  0.01
2020 Ma J, Thomas ME, McGuiggan P, Spicer JB. Weak absorption and scattering losses from the visible to the near-infrared in single-crystal sapphire materials Optical Engineering. 59: 1. DOI: 10.1117/1.OE.59.8.087101  0.01
2020 Spicer JB. The Landscape of Nanotechnology Education [Guest Editorial] Ieee Nanotechnology Magazine. 14: 12-12. DOI: 10.1109/mnano.2020.2994800  0.01
2020 Spicer JB. Dynamic, surface displacement measurements using a proximate, radiating electric dipole Aip Advances. 10: 015114. DOI: 10.1063/1.5115126  0.01
2019 Zeng FW, Zhang D, Spicer JB. Laser-Induced Precursor Decomposition for Nanoparticle Modification in Polymer Matrix Nanocomposites The Journal of Physical Chemistry C. 123: 19220-19229. DOI: 10.1021/ACS.JPCC.9B05290  0.01
2018 Zeng FW, Zhang D, Spicer JB. Effect of Polymer Structure on Precursor Diffusion and Particle Formation in Polymer Matrix Nanocomposites Journal of Inorganic and Organometallic Polymers and Materials. 28: 1850-1858. DOI: 10.1007/s10904-018-0843-6  0.01
2015 YOTSUJI J, SPICER JB. Metallic Surface Inspection Using Lateral Wave Microwave Techniques Sice Journal of Control, Measurement, and System Integration. 8: 279-284. DOI: 10.9746/JCMSI.8.279  0.01
2009 Spicer JB, Dikmelik Y. Elastic wavefield interactions with solute species during precipitation processes in solids Acta Materialia. 57: 1459-1465. DOI: 10.1016/J.ACTAMAT.2008.11.026  0.01
2007 Dikmelik Y, McEnnis C, Spicer JB, Dagdigian PJ. Femtosecond laser-induced breakdown spectroscopy of trinitrotoluene Conference On Lasers and Electro-Optics, 2007, Cleo 2007. DOI: 10.1109/CLEO.2007.4452900  0.01
2007 McEnnis C, Dikmelik Y, O'Brien B, Spicer JB, Zhang D, Lucia FCD, Miziolek AW. Laser-induced breakdown spectroscopy of polymer matrix nanocomposites Optics Infobase Conference Papers. DOI: 10.1109/CLEO.2007.4452899  0.01
2006 Suedel BC, Nicholson A, Day CH, Spicer J. The value of metals bioavailability and speciation information for ecological risk assessment in arid soils. Integrated Environmental Assessment and Management. 2: 355-64. PMID 17069177  0.01
2004 Chen Y, Liu H, Deng Y, Schauki D, Fitch MJ, Osiander R, Dodson C, Spicer JB, Shur M, Zhang X. THz spectroscopic investigation of 2,4-dinitrotoluene Chemical Physics Letters. 400: 357-361. DOI: 10.1016/J.Cplett.2004.10.117  0.01
2003 Spicer JB, Richardson CJK. Thermoelastic contributions to picosecond-timescale reflectivity measurements in metals (abstract) Review of Scientific Instruments. 74: 906-906. DOI: 10.1063/1.1521540  0.01
2002 Spicer JB, Richardson CJK. Ultrafast optoacoustic wave generation effects on picosecond‐timescale reflectivity measurements in metal thin films The Journal of the Acoustical Society of America. 112: 2349-2349. DOI: 10.1121/1.4779509  0.01
2001 Matsuda Y, Richardson CJK, Spicer JB. Spectral compression of ultrafast acoustic transients in thin films for enhanced detectability Applied Physics Letters. 79: 2288-2290. DOI: 10.1063/1.1407304  0.01
2000 Shull PJ, Hurley DH, Spicer JWM, Spicer JB. Spatial and temporal control of the degree of cure in polymer composite structures Polymer Engineering & Science. 40: 1157-1164. DOI: 10.1002/pen.11243  0.01
1999 Hurley DH, Spicer JB. Point-source representation for laser-generated ultrasound in an elastic, transversely isotropic half-space Journal of Applied Physics. 86: 3423-3427. DOI: 10.1063/1.371224  0.01
1996 Candy JV, Thomas GH, Chinn DJ, Spicer JB. Laser ultrasonic signal processing: A model‐reference approach The Journal of the Acoustical Society of America. 100: 278-284. DOI: 10.1121/1.415954  0.01
1990 Spicer JB, McKie ADW, Wagner JW. Quantitative theory for laser ultrasonic waves in a thin plate Applied Physics Letters. 57: 1882-1884. DOI: 10.1063/1.103999  0.01
1989 McKie A, Wagner J, Spicer J, Penney C. Laser generation of narrow-band and directed ultrasound Ultrasonics. 27: 323-330. DOI: 10.1016/0041-624X(89)90030-9  0.01
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