Enrique Alvarez, MD, PhD - Publications

Affiliations: 
Neurology University of Colorado, Boulder, Boulder, CO, United States 
Area:
multiple sclerosis, biomarkers

66 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2018 Zivadinov R, Medin J, Khan N, Korn JR, Chitnis T, Naismith RT, Alvarez E, Dwyer MG, Bergsland N, Carl E, Silva D, Weinstock-Guttman B. Impact of fingolimod on clinical and magnetic resonance imaging outcomes in routine clinical practice: A retrospective analysis of the multiple sclerosis, clinical and MRI outcomes in the USA (MS-MRIUS) study. Multiple Sclerosis and Related Disorders. 27: 65-73. PMID 30342416 DOI: 10.1016/j.msard.2018.09.037  0.68
2018 Fox RJ, Coffey CS, Conwit R, Cudkowicz ME, Gleason T, Goodman A, Klawiter EC, Matsuda K, McGovern M, Naismith RT, Ashokkumar A, Barnes J, Ecklund D, Klingner E, Koepp M, ... ... Alvarez E, et al. Phase 2 Trial of Ibudilast in Progressive Multiple Sclerosis. The New England Journal of Medicine. 379: 846-855. PMID 30157388 DOI: 10.1056/NEJMoa1803583  0.68
2018 Zivadinov R, Medin J, Khan N, Korn JR, Bergsland N, Dwyer MG, Chitnis T, Naismith RT, Alvarez E, Kinkel P, Cohan S, Hunter SF, Silva D, Weinstock-Guttman B. Fingolimod's Impact on MRI Brain Volume Measures in Multiple Sclerosis: Results from MS-MRIUS. Journal of Neuroimaging : Official Journal of the American Society of Neuroimaging. PMID 29749661 DOI: 10.1111/jon.12518  0.68
2017 Klawiter EC, Bove R, Elsone L, Alvarez E, Borisow N, Cortez M, Mateen F, Mealy MA, Sorum J, Mutch K, Tobyne SM, Ruprecht K, Buckle G, Levy M, Wingerchuk D, et al. High risk of postpartum relapses in neuromyelitis optica spectrum disorder. Neurology. PMID 29093070 DOI: 10.1212/WNL.0000000000004681  0.68
2017 Bove R, Elsone L, Alvarez E, Borisow N, Cortez MM, Mateen FJ, Mealy MA, Mutch K, Tobyne S, Ruprecht K, Buckle G, Levy M, Wingerchuk DM, Paul F, Cross AH, et al. Female hormonal exposures and neuromyelitis optica symptom onset in a multicenter study. Neurology(R) Neuroimmunology & Neuroinflammation. 4: e339. PMID 28382320 DOI: 10.1212/NXI.0000000000000339  0.68
2015 Alvarez E, Piccio L, Mikesell RJ, Trinkaus K, Parks BJ, Naismith RT, Cross AH. Predicting optimal response to B-cell depletion with rituximab in multiple sclerosis using CXCL13 index, magnetic resonance imaging and clinical measures. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 1: 2055217315623800. PMID 28607711 DOI: 10.1177/2055217315623800  0.68
2015 Patel KR, Luo J, Alvarez E, Piccio L, Schmidt RE, Yablonskiy DA, Cross AH. Detection of cortical lesions in multiple sclerosis: A new imaging approach. Multiple Sclerosis Journal - Experimental, Translational and Clinical. 1: 2055217315606465. PMID 28607704 DOI: 10.1177/2055217315606465  0.68
2015 Redondo N, Madan V, Alvarez E, Carrasco L. Impact of Vesicular Stomatitis Virus M Proteins on Different Cellular Functions. Plos One. 10: e0131137. PMID 26091335 DOI: 10.1371/journal.pone.0131137  1
2014 Moral-López P, Alvarez E, Redondo N, Skern T, Carrasco L. L protease from foot and mouth disease virus confers eIF2-independent translation for mRNAs bearing picornavirus IRES. Febs Letters. 588: 4053-9. PMID 25268112 DOI: 10.1016/j.febslet.2014.09.030  0.68
2013 Fenoglio C, Ridolfi E, Cantoni C, De Riz M, Bonsi R, Serpente M, Villa C, Pietroboni AM, Naismith RT, Alvarez E, Parks BJ, Bresolin N, Cross AH, Piccio LM, Galimberti D, et al. Decreased circulating miRNA levels in patients with primary progressive multiple sclerosis. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1938-42. PMID 24277735 DOI: 10.1177/1352458513485654  0.68
2013 Alvarez E, Piccio L, Mikesell RJ, Klawiter EC, Parks BJ, Naismith RT, Cross AH. CXCL13 is a biomarker of inflammation in multiple sclerosis, neuromyelitis optica, and other neurological conditions. Multiple Sclerosis (Houndmills, Basingstoke, England). 19: 1204-8. PMID 23322500 DOI: 10.1177/1352458512473362  0.68
2013 Wang LH, Bucelli RC, Patrick E, Rajderkar D, Alvarez Iii E, Lim MM, Debruin G, Sharma V, Dahiya S, Schmidt RE, Benzinger TS, Ward BA, Ances BM. Role of magnetic resonance imaging, cerebrospinal fluid, and electroencephalogram in diagnosis of sporadic Creutzfeldt-Jakob disease. Journal of Neurology. 260: 498-506. PMID 22968768 DOI: 10.1007/s00415-012-6664-6  0.68
2012 Qian P, Lancia S, Alvarez E, Klawiter EC, Cross AH, Naismith RT. Association of neuromyelitis optica with severe and intractable pain. Archives of Neurology. 69: 1482-7. PMID 22926050 DOI: 10.1001/archneurol.2012.768  0.68
2011 Álvarez E, Castelló A, Carrasco L, Izquierdo JM. Alternative splicing, a new target to block cellular gene expression by poliovirus 2A protease. Biochemical and Biophysical Research Communications. 414: 142-7. PMID 21945619 DOI: 10.1016/j.bbrc.2011.09.040  1
2011 Clifford DB, Ances B, Costello C, Rosen-Schmidt S, Andersson M, Parks D, Perry A, Yerra R, Schmidt R, Alvarez E, Tyler KL. Rituximab-associated progressive multifocal leukoencephalopathy in rheumatoid arthritis. Archives of Neurology. 68: 1156-64. PMID 21555606 DOI: 10.1001/archneurol.2011.103  0.68
2011 Castelló A, Alvarez E, Carrasco L. The multifaceted poliovirus 2A protease: regulation of gene expression by picornavirus proteases. Journal of Biomedicine & Biotechnology. 2011: 369648. PMID 21541224 DOI: 10.1155/2011/369648  1
2011 Wu GF, Alvarez E. The immunopathophysiology of multiple sclerosis. Neurologic Clinics. 29: 257-78. PMID 21439440 DOI: 10.1016/j.ncl.2010.12.009  0.68
2009 Castelló A, Franco D, Moral-López P, Berlanga JJ, Alvarez E, Wimmer E, Carrasco L. HIV- 1 protease inhibits Cap- and poly(A)-dependent translation upon eIF4GI and PABP cleavage. Plos One. 4: e7997. PMID 19956697 DOI: 10.1371/journal.pone.0007997  0.68
2009 Klawiter EC, Alvarez E, Xu J, Paciorkowski AR, Zhu L, Parks BJ, Cross AH, Naismith RT. NMO-IgG detected in CSF in seronegative neuromyelitis optica. Neurology. 72: 1101-3. PMID 19307546 DOI: 10.1212/01.wnl.0000345066.57745.50  0.68
2008 Zambrano O P, Delucchi B A, Cavagnaro S F, Hevia J P, Rosati M MP, Lagos R E, Nazal Ch V, González C C, Barrera B P, Alvarez L E, Pinto S V, Salas del C P, Cano Sch F, Contreras M A, Galanti de la P M, et al. [Hemolytic-uremic syndrome in Chile: clinical features, evolution and prognostic factors]. Revista MéDica De Chile. 136: 1240-6. PMID 19194619  0.68
2008 Caers J, Menu E, De Raeve H, Lepage D, Van Valckenborgh E, Van Camp B, Alvarez E, Vanderkerken K. Antitumour and antiangiogenic effects of Aplidin® in the 5TMM syngeneic models of multiple myeloma British Journal of Cancer. 98: 1966-1974. PMID 18521088 DOI: 10.1038/sj.bjc.6604388  0.68
2008 Lamirande EW, DeDiego ML, Roberts A, Jackson JP, Alvarez E, Sheahan T, Shieh WJ, Zaki SR, Baric R, Enjuanes L, Subbarao K. A live attenuated severe acute respiratory syndrome coronavirus is immunogenic and efficacious in golden Syrian hamsters. Journal of Virology. 82: 7721-4. PMID 18463152 DOI: 10.1128/JVI.00304-08  0.68
2008 Dediego ML, Pewe L, Alvarez E, Rejas MT, Perlman S, Enjuanes L. Pathogenicity of severe acute respiratory coronavirus deletion mutants in hACE-2 transgenic mice. Virology. 376: 379-89. PMID 18452964 DOI: 10.1016/j.virol.2008.03.005  0.68
2008 Muñoz-Alonso MJ, González-Santiago L, Zarich N, Martínez T, Alvarez E, Rojas JM, Muñoz A. Plitidepsin has a dual effect inhibiting cell cycle and inducing apoptosis via Rac1/c-Jun NH2-terminal kinase activation in human melanoma cells. The Journal of Pharmacology and Experimental Therapeutics. 324: 1093-101. PMID 18089842 DOI: 10.1124/jpet.107.132662  0.68
2008 Enjuanes L, Dediego ML, Alvarez E, Deming D, Sheahan T, Baric R. Vaccines to prevent severe acute respiratory syndrome coronavirus-induced disease. Virus Research. 133: 45-62. PMID 17416434 DOI: 10.1016/j.virusres.2007.01.021  0.68
2007 Gibson RJ, Bowen JM, Alvarez E, Finnie J, Keefe DM. Establishment of a single-dose irinotecan model of gastrointestinal mucositis. Chemotherapy. 53: 360-9. PMID 17713326 DOI: 10.1159/000107458  0.68
2007 Pollack VA, Alvarez E, Tse KF, Torgov MY, Xie S, Shenoy SG, MacDougall JR, Arrol S, Zhong H, Gerwien RW, Hahne WF, Senter PD, Jeffers ME, Lichenstein HS, LaRochelle WJ. Treatment parameters modulating regression of human melanoma xenografts by an antibody-drug conjugate (CR011-vcMMAE) targeting GPNMB. Cancer Chemotherapy and Pharmacology. 60: 423-35. PMID 17541593 DOI: 10.1007/s00280-007-0490-z  0.68
2007 Gibson RJ, Stringer AM, Bowen JM, Logan RM, Yeoh AS, Burns J, Alvarez E, Keefe DM. Velafermin improves gastrointestinal mucositis following irinotecan treatment in tumor-bearing DA rats. Cancer Biology & Therapy. 6: 541-7. PMID 17457046  0.68
2007 González-Santiago L, Alfonso P, Suárez Y, Núñez A, García-Fernández LF, Alvarez E, Muñoz A, Casal JI. Proteomic analysis of the resistance to aplidin in human cancer cells. Journal of Proteome Research. 6: 1286-94. PMID 17338558 DOI: 10.1021/pr060430+  0.68
2006 Almazán F, DeDiego ML, Galán C, Alvarez E, Enjuanes L. Identification of essential genes as a strategy to select a SARS candidate vaccine using a SARS-CoV infectious cDNA. Advances in Experimental Medicine and Biology. 581: 579-83. PMID 17037601  0.68
2006 Enjuanes L, Almazán F, Sola I, Zúñiga S, Alvarez E, Reguera J, Capiscol C. Biochemical aspects of coronavirus replication. Advances in Experimental Medicine and Biology. 581: 13-24. PMID 17037498 DOI: 10.1007/978-0-387-33012-9_2  0.68
2006 Castelló A, Alvarez E, Carrasco L. Differential cleavage of eIF4GI and eIF4GII in mammalian cells. Effects on translation. The Journal of Biological Chemistry. 281: 33206-16. PMID 16959778 DOI: 10.1074/jbc.M604340200  0.68
2006 Alvarez E, Castelló A, Menéndez-Arias L, Carrasco L. HIV protease cleaves poly(A)-binding protein. The Biochemical Journal. 396: 219-26. PMID 16594896 DOI: 10.1042/BJ20060108  1
2006 Ostendorf T, Rong S, Boor P, Wiedemann S, Kunter U, Haubold U, van Roeyen CR, Eitner F, Kawachi H, Starling G, Alvarez E, Smithson G, Floege J. Antagonism of PDGF-D by human antibody CR002 prevents renal scarring in experimental glomerulonephritis. Journal of the American Society of Nephrology : Jasn. 17: 1054-62. PMID 16510766 DOI: 10.1681/ASN.2005070683  0.68
2005 You J, Dove BK, Enjuanes L, DeDiego ML, Alvarez E, Howell G, Heinen P, Zambon M, Hiscox JA. Subcellular localization of the severe acute respiratory syndrome coronavirus nucleocapsid protein. The Journal of General Virology. 86: 3303-10. PMID 16298975 DOI: 10.1099/vir.0.81076-0  0.68
2005 Alvarez E, Zhou W, Witta SE, Freed CR. Characterization of the Bex gene family in humans, mice, and rats. Gene. 357: 18-28. PMID 15958283 DOI: 10.1016/j.gene.2005.05.012  0.68
2005 Dhanabal M, Wu F, Alvarez E, McQueeney KD, Jeffers M, MacDougall J, Boldog FL, Hackett C, Shenoy S, Khramtsov N, Weiner J, Lichenstein HS, LaRochelle WJ. Recombinant semaphorin 6A-1 ectodomain inhibits in vivo growth factor and tumor cell line-induced angiogenesis. Cancer Biology & Therapy. 4: 659-68. PMID 15917651  0.68
2004 Lobb KL, Hipskind PA, Aikins JA, Alvarez E, Cheung YY, Considine EL, De Dios A, Durst GL, Ferritto R, Grossman CS, Giera DD, Hollister BA, Huang Z, Iversen PW, Law KL, et al. Acyl sulfonamide anti-proliferatives: benzene substituent structure-activity relationships for a novel class of antitumor agents. Journal of Medicinal Chemistry. 47: 5367-80. PMID 15481975 DOI: 10.1021/jm030594r  0.68
2004 Buytaert-Hoefen KA, Alvarez E, Freed CR. Generation of tyrosine hydroxylase positive neurons from human embryonic stem cells after coculture with cellular substrates and exposure to GDNF. Stem Cells (Dayton, Ohio). 22: 669-74. PMID 15342931 DOI: 10.1634/stemcells.22-5-669  0.68
2003 Alvarez E, Westmore M, Galvin RJ, Clapp CL, Considine EL, Smith SJ, Keyes K, Iversen PW, Delafuente DM, Sulaimon S, Zambrano C, Ma L, Sato M, Martin TJ, Teicher BA, et al. Properties of bisphosphonates in the 13762 rat mammary carcinoma model of tumor-induced bone resorption. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. 9: 5705-13. PMID 14654555  0.68
2003 Alvarez E, Menéndez-Arias L, Carrasco L. The eukaryotic translation initiation factor 4GI is cleaved by different retroviral proteases. Journal of Virology. 77: 12392-400. PMID 14610163  1
2003 Keyes KA, Mann L, Teicher B, Alvarez E. Site-dependent angiogenic cytokine production in human tumor xenografts. Cytokine. 21: 98-104. PMID 12670449 DOI: 10.1016/S1043-4666(03)00015-2  0.68
2002 Kroep JR, Loves WJ, van der Wilt CL, Alvarez E, Talianidis I, Boven E, Braakhuis BJ, van Groeningen CJ, Pinedo HM, Peters GJ. Pretreatment deoxycytidine kinase levels predict in vivo gemcitabine sensitivity. Molecular Cancer Therapeutics. 1: 371-6. PMID 12477049  0.68
2002 Teicher BA, Menon K, Alvarez E, Shih C, Faul MM. Antiangiogenic and antitumor effects of a protein kinase Cbeta inhibitor in human breast cancer and ovarian cancer xenografts. Investigational New Drugs. 20: 241-51. PMID 12201487 DOI: 10.1023/A:1016297611825  0.68
2002 Teicher BA, Alvarez E, Menon K, Esterman MA, Considine E, Shih C, Faul MM. Antiangiogenic effects of a protein kinase Cbeta-selective small molecule. Cancer Chemotherapy and Pharmacology. 49: 69-77. PMID 11855754 DOI: 10.1007/s00280-001-0386-2  0.68
2001 Teicher BA, Menon K, Alvarez E, Galbreath E, Shih C, Faul MM. Antiangiogenic and antitumor effects of a protein kinase Cβ inhibitor in human HT-29 colon carcinoma and human CaKi1 renal cell carcinoma xenografts Anticancer Research. 21: 3175-3184. PMID 11848470  0.68
2001 Teicher BA, Menon K, Alvarez E, Galbreath E, Shih C, Faul MM. Antiangiogenic and antitumor effects of a protein kinase Cβ inhibitor in murine Lewis lung carcinoma and human Calu-6 non-small-cell lung carcinoma xenografts Cancer Chemotherapy and Pharmacology. 48: 473-480. PMID 11800028 DOI: 10.1007/s002800100372  0.68
2001 Ruiz-Pesini E, Alvarez E, Enríquez JA, López-Pérez MJ. Association between seminal plasma carnitine and sperm mitochondrial enzymatic activities International Journal of Andrology. 24: 335-340. PMID 11737414 DOI: 10.1046/j.1365-2605.2001.00311.x  0.68
2001 Teicher BA, Menon K, Alvarez E, Shih PLC, Faul MM. Antiangiogenic and antitumor effects of a protein kinase Cβ inhibitor in human hepatocellular and gastric cancer xenografts In Vivo. 15: 185-193. PMID 11491013  0.68
2001 Teicher BA, Menon K, Alvarez E, Galbreath E, Shih C, Faul M. Antiangiogenic and antitumor effects of a protein kinase Cβ inhibitor in human T98G glioblastoma multiforme xenografts Clinical Cancer Research. 7: 634-640. PMID 11297259  0.68
2000 van der Wilt CL, Kroep JR, Bergman AM, Loves WJ, Alvarez E, Talianidis I, Eriksson S, van Groeningen CJ, Pinedo HM, Peters GJ. The role of deoxycytidine kinase in gemcitabine cytotoxicity. Advances in Experimental Medicine and Biology. 486: 287-90. PMID 11783501  0.68
2000 Menon K, Alvarez E, Forler P, Phares V, Amsrud T, Shih C, Al-Awar R, Teicher BA. Antitumor activity of cryptophycins: Effect of infusion time and combination studies Cancer Chemotherapy and Pharmacology. 46: 142-149. PMID 10972484  0.68
2000 Ruiz-Pesini E, Lapena AC, Diez-Sanchez C, Perez-Martos A, Montoya J, Alvarez E, Diaz M, Urries A, Montoro L, Lopez-Perez MJ, Enriquez JA. Human mtDNA haplogroups associated with high or reduced spermatozoa motility American Journal of Human Genetics. 67: 682-696. PMID 10936107 DOI: 10.1086/303040  0.68
2000 Liu P, Menon K, Alvarez E, Lu K, Teicher BA. Transforming growth factor-beta and response to anticancer therapies in human liver and gastric tumors in vitro and in vivo International Journal of Oncology. 16: 599-610. PMID 10675495  0.68
1999 Mederos Cuervo LM, Alvarez E, Rosado A, Correa MT, Reyes M, Valdivia JA. Analysis of fatty acids from strains of Mycobacterium habana and Mycobacterium simiae | Análisis de ácidos grasos de cepas de Mycobacterium habana y Mycobacterium simiae Revista Cubana De Medicina Tropical. 51: 106-115. PMID 10887569  0.68
1999 Molina JA, Ruiz-Pesini E, Jiménez-Jiménez FJ, López-Pérez MJ, Alvarez E, Berbel A, Ortí-Pareja M, Zurdo M, Tallón-Barranco A, De Bustos F, Arenas J. Respiratory chain enzyme activities in spermatozoa from untreated Parkinson's disease patients Journal of Neural Transmission. 106: 919-924. PMID 10599873 DOI: 10.1007/s007020050211  0.68
1999 Teicher BA, Alvarez E, Liu P, Lu K, Menon K, Dempsey J, Schultz RM. MTA (LY231514) in combination treatment regimens using human tumor xenografts and the EMT-6 murine mammary carcinoma Seminars in Oncology. 26: 55-62. PMID 10598556  0.68
1999 Teicher BA, Alvarez E, Mendelsohn LG, Ara G, Menon K, Ways DK. Enzymatic rationale and preclinical support for a potent protein kinase Cβ inhibitor in cancer therapy Advances in Enzyme Regulation. 39: 313-327. PMID 10470381 DOI: 10.1016/S0065-2571(98)00026-0  0.68
1998 Fajardo EM, Ortiz B, Chávez A, Gaínza N, Izquierdo L, Hernández Y, Labrador I, Alvarez E. [Standardization of the lethal dose 50% of Leptospira interrogans strains used in the control of the leptospirosis cuban vaccine for human use]. Revista Cubana De Medicina Tropical. 50: 22-6. PMID 9842263  0.68
1998 Ruiz-Pesini E, Diez C, Lapena AC, Perez-Martos A, Montoya J, Alvarez E, Arenas J, Lopez-Perez MJ. Correlation of sperm motility with mitochondrial enzymatic activities Clinical Chemistry. 44: 1616-1620. PMID 9702947  0.68
1998 Fajardo EM, Plascencia Y, Chavez A, Munoz X, Sosa R, Alvarez E, Labrador I. Methodology for the establishment of the potency test of the whole-cell pertussis vaccine | Metodologia para el establecimiento del ensayo de potencia de la vacuna antipertussis de celulas completas Biotecnologia Aplicada. 15: 98-101.  0.68
1996 Norero V C, Delucchi B A, Lagos R E, Rosati M P, Cano F, Delucchi A, Rodríguez E, Saieh C, Cortés G, González E, Soto C, Wolff E, Contreras MA, Verdaguer M, Alvarez E, et al. Long term evaluation of two prednisone treatments in initial idiopathic nephrotic syndrome in children. Preliminary results | Cuadro inicial del sindrome nefrósico primario del niño: Evaluación a 18 meses de dos esquemas de tratamiento con prednisona Revista Medica De Chile. 124: 567-572. PMID 9035508  0.68
1995 Alamo M, Castro J, Alvarez E, Brunet L. Extracorporeal membrane oxygenation in adult respiratory distress syndrome. Experience in 2 patients | Oxigenación extracorpórea de membrana en sindrome de distrés respiratorio del adulto. Experiencia en 2 pacientes Revista MéDica De Chile. 123: 1275-1283. PMID 8733320  0.68
1995 Repiso T, García-Patos V, Alvarez E, Castells A. Generalized morphea associated with myelodysplastic syndrome | Morfea generalizada asociada a síndrome mielodisplásico Medicina Clinica. 105: 237. PMID 7658747  0.68
1994 Alvarez E, Falcó V, Barbé J, Ocaña I. Cryptococcal infection of the central nervous system and blindness as its sequela | Afección del sistema nervioso central por criptococo y ceguera como secuela de la misma Medicina Clinica. 102: 517. PMID 8208014  0.68
1989 Blasco E, Torrado J, Cosme A, Alvarez E, Zugasti A, Gutierrez-Hoyos A, Arenas JI. Expression of Lewis antigenic determinants in colorectal adenocarcinomas. Experimental Cell Biology. 57: 153-8. PMID 2476347  0.68
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