Shyam S. Sharma, PhD - Publications

Affiliations: 
1999- Department of Pharmacology and Toxicology National Institute of Pharmaceutical Education and Research, Mohali 
Area:
Neuropharmacology
Website:
www.niper.ac.in

65 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2023 Adhya P, Vaidya B, Sharma SS. BTD: A TRPC5 activatorameliorates mechanical allodynia in diabetic peripheral neuropathic rats by modulating TRPC5-CAMKII-ERK pathway. Neurochemistry International. 105609. PMID 37673218 DOI: 10.1016/j.neuint.2023.105609  0.355
2023 Adhya P, Sharma SS. Transient receptor potential canonical 5 (TRPC5) channels activator, BTD [N-{3-(adamantan-2-yloxy)-propyl}-3-(6-methyl-1,1-dioxo-2H-1λ6,2,4-benzothiadiazin-3-yl)-propanamide)] ameliorates diabetic cardiac autonomic neuropathy in rats. Current Neurovascular Research. PMID 37013433 DOI: 10.2174/1567202620666230403134627  0.312
2021 Kaundal RK, Datusalia AK, Sharma SS. Posttranscriptional regulation of Nrf2 through miRNAs and their role in Alzheimer's disease. Pharmacological Research. 175: 106018. PMID 34863823 DOI: 10.1016/j.phrs.2021.106018  0.607
2020 Thapak P, Bishnoi M, Sharma SS. Pharmacological inhibition of Transient Receptor Potential Melastatin 2 (TRPM2) Channels Attenuates Diabetes-induced Cognitive Deficits in Rats: A Mechanistic Study. Current Neurovascular Research. PMID 32294037 DOI: 10.2174/1567202617666200415142211  0.465
2020 Resham K, Khare P, Bishnoi M, Sharma SS. Neuroprotective effects of isoquercitrin in diabetic neuropathy via Wnt/β-catenin signaling pathway inhibition. Biofactors (Oxford, England). PMID 31960520 DOI: 10.1002/Biof.1615  0.493
2019 Resham K, Sharma SS. Pharmacological interventions targeting Wnt/β-catenin signaling pathway attenuate paclitaxel-induced peripheral neuropathy. European Journal of Pharmacology. 172714. PMID 31586636 DOI: 10.1016/J.Ejphar.2019.172714  0.319
2019 Nankar SA, Bulani Y, Sharma SS, Pande AH. APOE-Derived Peptides Attenuated Diabetes-Induced Oxidative Stress and Inflammation. Protein and Peptide Letters. PMID 31577194 DOI: 10.2174/0929866526666191002112655  0.326
2019 Adhya P, Sharma SS. Redox TRPs in diabetes and diabetic complications: mechanisms and pharmacological modulation. Pharmacological Research. 104271. PMID 31096011 DOI: 10.1016/J.Phrs.2019.104271  0.475
2019 Resham K, Sharma SS. Pharmacological Inhibition of Porcupine, Disheveled and β-catenin in Wnt Signaling Pathway Ameliorates Diabetic Peripheral Neuropathy in Rats. The Journal of Pain : Official Journal of the American Pain Society. PMID 31075529 DOI: 10.1016/J.Jpain.2019.04.010  0.46
2018 Datusalia AK, Agarwal P, Singh JN, Sharma SS. Hyper-insulinemia increases the glutamate-excitotoxicity in cortical neurons: A mechanistic study. European Journal of Pharmacology. 833: 524-530. PMID 30017861 DOI: 10.1016/J.Ejphar.2018.07.001  0.658
2018 Bulani Y, Srinivasan K, Sharma SS. Attenuation of type-1 diabetes-induced cardiovascular dysfunctions by direct thrombin inhibitor in rats: a mechanistic study. Molecular and Cellular Biochemistry. PMID 29971544 DOI: 10.1007/S11010-018-3394-9  0.493
2017 Bulani Y, Sharma SS. Argatroban Attenuates Diabetic Cardiomyopathy in Rats by Reducing Fibrosis, Inflammation, Apoptosis, and Protease-Activated Receptor Expression. Cardiovascular Drugs and Therapy. PMID 28695302 DOI: 10.1007/s10557-017-6732-3  0.349
2016 Sharma D, Singh JN, Sharma SS. Effects of 4-phenyl butyric acid on high glucose-induced alterations in dorsal root ganglion neurons. Neuroscience Letters. PMID 27777138 DOI: 10.1016/J.Neulet.2016.10.038  0.399
2016 Khare P, Datusalia AK, Sharma SS. Parthenolide, an NF-κB Inhibitor Ameliorates Diabetes-Induced Behavioural Deficit, Neurotransmitter Imbalance and Neuroinflammation in Type 2 Diabetes Rat Model. Neuromolecular Medicine. PMID 27553015 DOI: 10.1007/S12017-016-8434-6  0.748
2016 Jawale A, Datusalia AK, Bishnoi M, Sharma SS. Reversal of diabetes-induced behavioral and neurochemical deficits by cinnamaldehyde. Phytomedicine : International Journal of Phytotherapy and Phytopharmacology. 23: 923-30. PMID 27387400 DOI: 10.1016/J.Phymed.2016.04.008  0.732
2016 Bajaj P, Tripathy RK, Aggarwal G, Datusalia AK, Sharma SS, Pande AH. Refolded Recombinant Human Paraoxonase 1 Variant Exhibits Prophylactic Activity Against Organophosphate Poisoning. Applied Biochemistry and Biotechnology. PMID 27131877 DOI: 10.1007/S12010-016-2091-Y  0.635
2016 Komirishetty P, Areti A, Yerra VG, Pk R, Sharma SS, Gogoi R, Sistla R, Kumar A. PARP inhibition attenuates neuroinflammation and oxidative stress in chronic constriction injury induced peripheral neuropathy. Life Sciences. PMID 26921631 DOI: 10.1016/J.Lfs.2016.02.085  0.351
2016 Datusalia AK, Sharma SS. Inhibition of GSK-3beta signalling improves cognitive deficits and glutamate-excitotoxicity in diabetes through transcription regulation of CREB European Neuropsychopharmacology. 26. DOI: 10.1016/S0924-977X(16)31101-4  0.702
2015 Datusalia AK, Sharma SS. NF-κB Inhibition Resolves Cognitive Deficits in Experimental Type 2 Diabetes Mellitus through CREB and Glutamate/GABA Neurotransmitters Pathway. Current Neurovascular Research. PMID 26517200 DOI: 10.2174/1567202612666151030104810  0.735
2015 Negi G, Nakkina V, Kamble P, Sharma SS. Heme oxygenase-1, a novel target for the treatment of diabetic complications: focus on diabetic peripheral neuropathy. Pharmacological Research. 102: 158-167. PMID 26432957 DOI: 10.1016/J.Phrs.2015.09.014  0.485
2015 Kharatmal SB, Singh JN, Sharma SS. Comparative evaluation of in vitro and in vivo high glucose-induced alterations in voltage-gated tetrodotoxin-resistant sodium channel: Effects attenuated by sodium channel blockers. Neuroscience. 305: 183-196. PMID 26255676 DOI: 10.1016/J.Neuroscience.2015.07.085  0.417
2015 Kharatmal SB, Singh JN, Sharma SS. Voltage-Gated Sodium Channels as Therapeutic Targets for Treatment of Painful Diabetic Neuropathy. Mini Reviews in Medicinal Chemistry. PMID 26202189 DOI: 10.2174/1389557515666150722112621  0.403
2015 Kharatmal SB, Singh JN, Sharma SS. Calpain inhibitor, MDL 28170 confer electrophysiological, nociceptive and biochemical improvement in diabetic neuropathy. Neuropharmacology. PMID 26087461 DOI: 10.1016/J.Neuropharm.2015.05.040  0.493
2015 Kharatmal SB, Singh JN, Sharma SS. Rufinamide Improves Functional and Behavioral Deficits via Blockade of Tetrodotoxin-Resistant Sodium Channels in Diabetic Neuropathy. Current Neurovascular Research. PMID 26036975 DOI: 10.2174/1567202612666150603130402  0.47
2015 Sharma M, Akhtar N, Sambhav K, Shete G, Bansal AK, Sharma SS. Emerging potential of citrus flavanones as an antioxidant in diabetes and its complications. Current Topics in Medicinal Chemistry. 15: 187-95. PMID 25547100 DOI: 10.2174/1568026615666141209163013  0.449
2015 Negi G, Sharma SS. Inhibition of IκB kinase (IKK) protects against peripheral nerve dysfunction of experimental diabetes. Molecular Neurobiology. 51: 591-8. PMID 24946751 DOI: 10.1007/S12035-014-8784-8  0.466
2014 Meerupally R, Singh JN, Sharma SS. Diabetic-induced increased sodium channel activity attenuated by tetracaine in sensory neurons in vitro. Biochemical and Biophysical Research Communications. 453: 296-301. PMID 25234593 DOI: 10.1016/J.Bbrc.2014.09.035  0.439
2014 Jangra A, Datusalia AK, Sharma SS. Reversal of neurobehavioral and neurochemical alterations in STZ-induced diabetic rats by FeTMPyP, a peroxynitrite decomposition catalyst and 1,5-Isoquinolinediol a poly(ADP-ribose) polymerase inhibitor. Neurological Research. 36: 619-26. PMID 24620961 DOI: 10.1179/1743132813Y.0000000301  0.713
2014 Datusalia AK, Sharma SS. Amelioration of diabetes-induced cognitive deficits by GSK-3β inhibition is attributed to modulation of neurotransmitters and neuroinflammation. Molecular Neurobiology. 50: 390-405. PMID 24420785 DOI: 10.1007/S12035-014-8632-X  0.727
2013 Kumar A, Negi G, Sharma SS. Neuroprotection by resveratrol in diabetic neuropathy: concepts & mechanisms. Current Medicinal Chemistry. 20: 4640-5. PMID 24206125 DOI: 10.2174/09298673113209990151  0.499
2013 Jangra A, Datusalia AK, Khandwe S, Sharma SS. Amelioration of diabetes-induced neurobehavioral and neurochemical changes by melatonin and nicotinamide: implication of oxidative stress-PARP pathway. Pharmacology, Biochemistry, and Behavior. 114: 43-51. PMID 24201044 DOI: 10.1016/J.Pbb.2013.10.021  0.737
2013 Ganesh Yerra V, Negi G, Sharma SS, Kumar A. Potential therapeutic effects of the simultaneous targeting of the Nrf2 and NF-κB pathways in diabetic neuropathy. Redox Biology. 1: 394-7. PMID 24024177 DOI: 10.1016/J.Redox.2013.07.005  0.431
2013 Joshi RP, Negi G, Kumar A, Pawar YB, Munjal B, Bansal AK, Sharma SS. SNEDDS curcumin formulation leads to enhanced protection from pain and functional deficits associated with diabetic neuropathy: an insight into its mechanism for neuroprotection. Nanomedicine : Nanotechnology, Biology, and Medicine. 9: 776-85. PMID 23347896 DOI: 10.1016/J.Nano.2013.01.001  0.492
2012 Kumar A, Negi G, Sharma SS. Suppression of NF-κB and NF-κB regulated oxidative stress and neuroinflammation by BAY 11-7082 (IκB phosphorylation inhibitor) in experimental diabetic neuropathy. Biochimie. 94: 1158-65. PMID 22342224 DOI: 10.1016/J.Biochi.2012.01.023  0.495
2012 Srinivasan K, Sharma SS. 3-Bromo-7-nitroindazole attenuates brain ischemic injury in diabetic stroke via inhibition of endoplasmic reticulum stress pathway involving CHOP. Life Sciences. 90: 154-60. PMID 22075494 DOI: 10.1016/J.Lfs.2011.10.017  0.482
2012 Srinivasan K, Sharma SS. Edaravone offers neuroprotection in a diabetic stroke model via inhibition of endoplasmic reticulum stress. Basic & Clinical Pharmacology & Toxicology. 110: 133-40. PMID 21752197 DOI: 10.1111/J.1742-7843.2011.00763.X  0.464
2011 Negi G, Kumar A, Sharma SS. Nrf2 and NF-κB modulation by sulforaphane counteracts multiple manifestations of diabetic neuropathy in rats and high glucose-induced changes. Current Neurovascular Research. 8: 294-304. PMID 22023613 DOI: 10.2174/156720211798120972  0.52
2011 Srinivasan K, Sharma SS. Augmentation of endoplasmic reticulum stress in cerebral ischemia/reperfusion injury associated with comorbid type 2 diabetes. Neurological Research. 33: 858-65. PMID 22004710 DOI: 10.1179/1743132811Y.0000000015  0.32
2011 Srinivasan K, Sharma SS. Sodium phenylbutyrate ameliorates focal cerebral ischemic/reperfusion injury associated with comorbid type 2 diabetes by reducing endoplasmic reticulum stress and DNA fragmentation. Behavioural Brain Research. 225: 110-6. PMID 21767572 DOI: 10.1016/J.Bbr.2011.07.004  0.441
2011 Kaundal RK, Sharma SS. Ameliorative effects of GW1929, a nonthiazolidinedione PPARγ agonist, on inflammation and apoptosis in focal cerebral ischemic-reperfusion injury. Current Neurovascular Research. 8: 236-45. PMID 21722092 DOI: 10.2174/156720211796558078  0.308
2011 Kumar A, Negi G, Sharma SS. JSH-23 targets nuclear factor-kappa B and reverses various deficits in experimental diabetic neuropathy: effect on neuroinflammation and antioxidant defence. Diabetes, Obesity & Metabolism. 13: 750-8. PMID 21447040 DOI: 10.1111/J.1463-1326.2011.01402.X  0.487
2011 Negi G, Kumar A, Joshi RP, Sharma SS. Oxidative stress and Nrf2 in the pathophysiology of diabetic neuropathy: old perspective with a new angle. Biochemical and Biophysical Research Communications. 408: 1-5. PMID 21439933 DOI: 10.1016/J.Bbrc.2011.03.087  0.492
2011 Negi G, Kumar A, Sharma SS. Melatonin modulates neuroinflammation and oxidative stress in experimental diabetic neuropathy: effects on NF-κB and Nrf2 cascades. Journal of Pineal Research. 50: 124-31. PMID 21062351 DOI: 10.1111/J.1600-079X.2010.00821.X  0.496
2011 Kaundal RK, Sharma SS. GW1929: a nonthiazolidinedione PPARγ agonist, ameliorates neurological damage in global cerebral ischemic-reperfusion injury through reduction in inflammation and DNA fragmentation. Behavioural Brain Research. 216: 606-12. PMID 20833208 DOI: 10.1016/J.Bbr.2010.09.001  0.319
2011 Negi G, Kumar A, Sharma SS. Adopting Nrf2 and NF-κB from cancer: Is there any role of the duo in diabetes? Nature Precedings. 6: 1-1. DOI: 10.1038/Npre.2011.6581.1  0.42
2010 Kaundal RK, Sharma SS. Peroxisome proliferator-activated receptor gamma agonists as neuroprotective agents. Drug News & Perspectives. 23: 241-56. PMID 20520853 DOI: 10.1358/Dnp.2010.23.4.1437710  0.322
2010 Kumar A, Sharma SS. NF-kappaB inhibitory action of resveratrol: a probable mechanism of neuroprotection in experimental diabetic neuropathy. Biochemical and Biophysical Research Communications. 394: 360-5. PMID 20211601 DOI: 10.1016/J.Bbrc.2010.03.014  0.458
2010 Negi G, Kumar A, Kaundal RK, Gulati A, Sharma SS. Functional and biochemical evidence indicating beneficial effect of Melatonin and Nicotinamide alone and in combination in experimental diabetic neuropathy. Neuropharmacology. 58: 585-92. PMID 20005237 DOI: 10.1016/J.Neuropharm.2009.11.018  0.484
2010 Negi G, Kumar A, Sharma SS. Concurrent targeting of nitrosative stress-PARP pathway corrects functional, behavioral and biochemical deficits in experimental diabetic neuropathy. Biochemical and Biophysical Research Communications. 391: 102-6. PMID 19900402 DOI: 10.1016/J.Bbrc.2009.11.010  0.409
2009 Kaundal RK, Iyer S, Kumar A, Sharma SS. Protective effects of pioglitazone against global cerebral ischemic-reperfusion injury in gerbils. Journal of Pharmacological Sciences. 109: 361-7. PMID 19305120 DOI: 10.1254/Jphs.08246Fp  0.301
2009 Sharma SS, Kumar A, Arora M, Kaundal RK. Neuroprotective potential of combination of resveratrol and 4-amino 1,8 naphthalimide in experimental diabetic neuropathy: focus on functional, sensorimotor and biochemical changes. Free Radical Research. 43: 400-8. PMID 19291593 DOI: 10.1080/10715760902801509  0.492
2009 Kumar P, Kaundal RK, More S, Sharma SS. Beneficial effects of pioglitazone on cognitive impairment in MPTP model of Parkinson's disease. Behavioural Brain Research. 197: 398-403. PMID 18983875 DOI: 10.1016/J.Bbr.2008.10.010  0.34
2008 Arora M, Kumar A, Kaundal RK, Sharma SS. Amelioration of neurological and biochemical deficits by peroxynitrite decomposition catalysts in experimental diabetic neuropathy. European Journal of Pharmacology. 596: 77-83. PMID 18768138 DOI: 10.1016/J.Ejphar.2008.08.003  0.481
2008 Sharma SS, Kumar A, Kaundal RK. Protective effects of 4-amino1,8-napthalimide, a poly (ADP-ribose) polymerase inhibitor in experimental diabetic neuropathy. Life Sciences. 82: 570-6. PMID 18262571 DOI: 10.1016/J.Lfs.2007.11.031  0.492
2007 Saini AK, Kumar H S A, Sharma SS. Preventive and curative effect of edaravone on nerve functions and oxidative stress in experimental diabetic neuropathy. European Journal of Pharmacology. 568: 164-72. PMID 17521626 DOI: 10.1016/j.ejphar.2007.04.016  0.398
2007 Sharma SS, Gupta S. Neuroprotective effect of MnTMPyP, a superoxide dismutase/catalase mimetic in global cerebral ischemia is mediated through reduction of oxidative stress and DNA fragmentation. European Journal of Pharmacology. 561: 72-9. PMID 17320858 DOI: 10.1016/J.Ejphar.2006.12.039  0.333
2007 Sharma SS, Dhar A, Kaundal RK. FeTPPS protects against global cerebral ischemic-reperfusion injury in gerbils. Pharmacological Research. 55: 335-42. PMID 17292620 DOI: 10.1016/J.Phrs.2007.01.002  0.31
2007 Kumar A, Kaundal RK, Iyer S, Sharma SS. Effects of resveratrol on nerve functions, oxidative stress and DNA fragmentation in experimental diabetic neuropathy. Life Sciences. 80: 1236-44. PMID 17289084 DOI: 10.1016/J.Lfs.2006.12.036  0.497
2006 Sharma SS, Sayyed SG. Effects of trolox on nerve dysfunction, thermal hyperalgesia and oxidative stress in experimental diabetic neuropathy. Clinical and Experimental Pharmacology & Physiology. 33: 1022-8. PMID 17042909 DOI: 10.1111/J.1440-1681.2006.04481.X  0.506
2006 Kaundal RK, Shah KK, Sharma SS. Neuroprotective effects of NU1025, a PARP inhibitor in cerebral ischemia are mediated through reduction in NAD depletion and DNA fragmentation. Life Sciences. 79: 2293-302. PMID 16935310 DOI: 10.1016/J.Lfs.2006.07.034  0.324
2006 Dhar A, Kaundal RK, Sharma SS. Neuroprotective effects of FeTMPyP: a peroxynitrite decomposition catalyst in global cerebral ischemia model in gerbils. Pharmacological Research. 54: 311-6. PMID 16877004 DOI: 10.1016/J.Phrs.2006.06.009  0.306
2006 Sayyed SG, Kumar A, Sharma SS. Effects of U83836E on nerve functions, hyperalgesia and oxidative stress in experimental diabetic neuropathy. Life Sciences. 79: 777-83. PMID 16581090 DOI: 10.1016/J.Lfs.2006.02.033  0.519
2006 Saini AK, Patel RJ, Sharma SS, H S AK. Edaravone attenuates hydroxyl radical stress and augmented angiotensin II response in diabetic rats. Pharmacological Research. 54: 6-10. PMID 16545576 DOI: 10.1016/J.Phrs.2006.02.003  0.441
2005 Kumar S, Arun KH, Kaul CL, Sharma SS. Effects of adenosine and adenosine A2A receptor agonist on motor nerve conduction velocity and nerve blood flow in experimental diabetic neuropathy. Neurological Research. 27: 60-6. PMID 15829161 DOI: 10.1179/016164105X18278  0.356
2004 Thiyagarajan M, Sharma SS. Neuroprotective effect of curcumin in middle cerebral artery occlusion induced focal cerebral ischemia in rats. Life Sciences. 74: 969-85. PMID 14672754 DOI: 10.1016/J.Lfs.2003.06.042  0.331
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