Carmen Aragon, Ph.D. - Publications

Affiliations: 
Molecular Neurobiology Centro de Biología Molecular Severo Ochoa 
Area:
Molecular Neurobiology

57 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2021 de la Rocha-Muñoz A, Núñez E, Vishwanath AA, Gómez-López S, Dhanasobhon D, Rebola N, López-Corcuera B, de Juan-Sanz J, Aragón C. The presynaptic glycine transporter GlyT2 is regulated by the Hedgehog pathway in vitro and in vivo. Communications Biology. 4: 1197. PMID 34663888 DOI: 10.1038/s42003-021-02718-6  0.68
2021 Benito-Muñoz C, Perona A, Felipe R, Pérez-Siles G, Núñez E, Aragón C, López-Corcuera B. Structural Determinants of the Neuronal Glycine Transporter 2 for the Selective Inhibitors ALX1393 and ORG25543. Acs Chemical Neuroscience. PMID 34003005 DOI: 10.1021/acschemneuro.0c00602  0.37
2021 de la Rocha-Muñoz A, Melgarejo E, Aragón C, López-Corcuera B. Rescue of two trafficking-defective variants of the neuronal glycine transporter GlyT2 associated to hyperekplexia. Neuropharmacology. 189: 108543. PMID 33794243 DOI: 10.1016/j.neuropharm.2021.108543  0.418
2019 de la Rocha-Muñoz A, Núñez E, Arribas-González E, López-Corcuera B, Aragón C, de Juan-Sanz J. E3 ubiquitin ligases LNX1 and LNX2 are major regulators of the presynaptic glycine transporter GlyT2. Scientific Reports. 9: 14944. PMID 31628376 DOI: 10.1038/S41598-019-51301-X  0.49
2019 López-Corcuera B, Arribas-González E, Aragón C. Hyperekplexia-associated mutations in the neuronal glycine transporter 2. Neurochemistry International. 123: 95-100. PMID 29859229 DOI: 10.1016/J.Neuint.2018.05.014  0.396
2018 Benito-Muñoz C, Perona A, Abia D, Dos Santos HG, Núñez E, Aragón C, López-Corcuera B. Modification of a Putative Third Sodium Site in the Glycine Transporter GlyT2 Influences the Chloride Dependence of Substrate Transport. Frontiers in Molecular Neuroscience. 11: 347. PMID 30319354 DOI: 10.3389/Fnmol.2018.00347  0.494
2017 López-Corcuera B, Benito-Muñoz C, Aragón C. Glycine Transporters in Glia Cells: Structural Studies. Advances in Neurobiology. 16: 13-32. PMID 28828604 DOI: 10.1007/978-3-319-55769-4_2  0.557
2017 Villarejo-López L, Jiménez E, Bartolomé-Martín D, Zafra F, Lapunzina P, Aragón C, López-Corcuera B. P2X receptors up-regulate the cell-surface expression of the neuronal glycine transporter GlyT2. Neuropharmacology. PMID 28734869 DOI: 10.1016/J.Neuropharm.2017.07.018  0.47
2015 Jiménez E, Núñez E, Ibáñez I, Zafra F, Aragón C, Giménez C. Glycine transporters GlyT1 and GlyT2 are differentially modulated by glycogen synthase kinase 3β. Neuropharmacology. 89: 245-54. PMID 25301276 DOI: 10.1016/J.Neuropharm.2014.09.023  0.479
2013 Arribas-González E, Alonso-Torres P, Aragón C, López-Corcuera B. Calnexin-assisted biogenesis of the neuronal glycine transporter 2 (GlyT2). Plos One. 8. PMID 23650557 DOI: 10.1371/Journal.Pone.0063230  0.546
2012 Werdehausen R, Kremer D, Brandenburger T, Schlösser L, Jadasz J, Küry P, Bauer I, Aragón C, Eulenburg V, Hermanns H. Lidocaine metabolites inhibit glycine transporter 1: a novel mechanism for the analgesic action of systemic lidocaine? Anesthesiology. 116: 147-58. PMID 22133759 DOI: 10.1097/ALN.0b013e31823cf233  0.443
2012 Pérez-Siles G, Núñez E, Morreale A, Jiménez E, Leo-Macías A, Pita G, Cherubino F, Sangaletti R, Bossi E, Ortíz AR, Aragón C, López-Corcuera B. An aspartate residue in the external vestibule of GLYT2 (glycine transporter 2) controls cation access and transport coupling. The Biochemical Journal. 442: 323-34. PMID 22132725 DOI: 10.1042/Bj20110247  0.384
2011 Pérez-Siles G, Morreale A, Leo-Macías A, Pita G, Ortíz AR, Aragón C, López-Corcuera B. Molecular basis of the differential interaction with lithium of glycine transporters GLYT1 and GLYT2. Journal of Neurochemistry. 118: 195-204. PMID 21574997 DOI: 10.1111/J.1471-4159.2011.07309.X  0.492
2011 Jiménez E, Zafra F, Pérez-Sen R, Delicado EG, Miras-Portugal MT, Aragón C, López-Corcuera B. P2Y purinergic regulation of the glycine neurotransmitter transporters. The Journal of Biological Chemistry. 286: 10712-24. PMID 21245148 DOI: 10.1074/Jbc.M110.167056  0.471
2009 Núñez E, Pérez-Siles G, Rodenstein L, Alonso-Torres P, Zafra F, Jiménez E, Aragón C, López-Corcuera B. Subcellular localization of the neuronal glycine transporter GLYT2 in brainstem. Traffic (Copenhagen, Denmark). 10: 829-43. PMID 19374720 DOI: 10.1111/J.1600-0854.2009.00911.X  0.561
2008 Fornés A, Núñez E, Alonso-Torres P, Aragón C, López-Corcuera B. Trafficking properties and activity regulation of the neuronal glycine transporter GLYT2 by protein kinase C. Biochemical Journal. 412: 495-506. PMID 18341477 DOI: 10.1042/Bj20071018  0.537
2008 Núñez E, Alonso-Torres P, Fornés A, Aragón C, López-Corcuera B. The neuronal glycine transporter GLYT2 associates with membrane rafts: functional modulation by lipid environment Journal of Neurochemistry. 105: 2080-2090. PMID 18266927 DOI: 10.1111/J.1471-4159.2008.05292.X  0.432
2005 Núñez E, Martínez-Maza R, Geerlings A, Aragón C, López-Corcuera B. Transmembrane domains 1 and 3 of the glycine transporter GLYT1 contain structural determinants of N[3-(4'-fluorophenyl)-3-(4'-phenylphenoxy)-propyl]sarcosine specificity. Neuropharmacology. 49: 922-34. PMID 16143353 DOI: 10.1016/J.Neuropharm.2005.07.010  0.479
2005 Aragón C, López-Corcuera B. Glycine transporters: crucial roles of pharmacological interest revealed by gene deletion. Trends in Pharmacological Sciences. 26: 283-286. PMID 15925702 DOI: 10.1016/J.Tips.2005.04.007  0.391
2004 Fornés A, Núñez E, Aragón C, López-Corcuera B. The second intracellular loop of the glycine transporter 2 contains crucial residues for glycine transport and phorbol ester-induced regulation. Journal of Biological Chemistry. 279: 22934-22943. PMID 15010455 DOI: 10.1074/Jbc.M401337200  0.551
2003 Aragón C, López-Corcuera B. Structure, function and regulation of glycine neurotransporters. European Journal of Pharmacology. 479: 249-262. PMID 14612155 DOI: 10.1016/J.Ejphar.2003.08.074  0.511
2002 Geerlings A, Núñez E, Rodenstein L, López-Corcuera B, Aragón C. Glycine transporter isoforms show differential subcellular localization in PC12 cells Journal of Neurochemistry. 82: 58-65. PMID 12091465 DOI: 10.1046/J.1471-4159.2002.00930.X  0.499
2002 López-Corcuera B, Aragón C, Geerlings A. Regulation of glycine transporters. Biochemical Society Transactions. 29: 742-5. PMID 11709067 DOI: 10.1042/0300-5127:0290742  0.446
2001 López-Corcuera B, Núñez E, Martínez-Maza R, Geerlings A, Aragón C. Substrate-induced conformational changes of extracellular loop 1 in the glycine transporter GLYT2. The Journal of Biological Chemistry. 276: 43463-70. PMID 11551961 DOI: 10.1074/Jbc.M107438200  0.507
2001 López-Corcuera B, Geerlings A, Aragón C. Glycine neurotransmitter transporters: an update. Molecular Membrane Biology. 18: 13-20. PMID 11396606  0.413
2001 Geerlings A, Núñez E, López-Corcuera B, Aragón C. Calcium- and syntaxin 1-mediated trafficking of the neuronal glycine transporter GLYT2. The Journal of Biological Chemistry. 276: 17584-90. PMID 11278707 DOI: 10.1074/Jbc.M010602200  0.53
2001 Roux MJ, Martinez-Maza R, Le Goff A, Lopez-Corcuera B, Aragon C, Supplisson S. The glial and the neuronal glycine transporters differ in their reactivity to sulfhydryl reagents. The Journal of Biological Chemistry. 276: 17699-705. PMID 11278474 DOI: 10.1074/Jbc.M009196200  0.427
2001 López-Corcuera B, Geerlings A, Aragón C. Glycine neurotransmitter transporters: an update Molecular Membrane Biology. 18: 13-20. DOI: 10.1080/09687680010028762  0.469
2001 López-Corcuera B, Aragón C, Geerlings A. Regulation of glycine transporters Biochemical Society Transactions. 29: 742-745. DOI: 10.1042/Bst0290742  0.525
2000 Martínez-Maza R, Poyatos I, López-Corcuera B, N úñez E, Giménez C, Zafra F, Aragón C. The role of N-glycosylation in transport to the plasma membrane and sorting of the neuronal glycine transporter GLYT2. The Journal of Biological Chemistry. 276: 2168-73. PMID 11036075 DOI: 10.1074/Jbc.M006774200  0.517
2000 Ponce J, Biton B, Benavides J, Avenet P, Aragon C. Transmembrane domain III plays an important role in ion binding and permeation in the glycine transporter GLYT2. The Journal of Biological Chemistry. 275: 13856-62. PMID 10788509 DOI: 10.1074/Jbc.275.18.13856  0.483
2000 Geerlings A, López-Corcuera B, Aragón C. Characterization of the interactions between the glycine transporters GLYT1 and GLYT2 and the SNARE protein syntaxin 1A. Febs Letters. 470: 51-4. PMID 10722844 DOI: 10.1016/S0014-5793(00)01297-7  0.41
2000 Núñez E, López-Corcuera B, Vázquez J, Giménez C, Aragón C. Differential effects of the tricyclic antidepressant amoxapine on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters. British Journal of Pharmacology. 129: 200-6. PMID 10694221 DOI: 10.1038/Sj.Bjp.0703049  0.499
2000 Núñez E, López-Corcuera B, Martínez-Maza R, Aragón C. Differential effects of ethanol on glycine uptake mediated by the recombinant GLYT1 and GLYT2 glycine transporters. British Journal of Pharmacology. 129: 802-10. PMID 10683205 DOI: 10.1038/Sj.Bjp.0703100  0.41
1998 Aragón C, López-Corcuera B. Purification, hydrodynamic properties, and glycosylation analysis of glycine transporters. Methods in Enzymology. 296: 3-17. PMID 9779437 DOI: 10.1016/S0076-6879(98)96003-7  0.532
1998 Ponce J, Poyatos I, Aragón C, Giménez C, Zafra F. Characterization of the 5′ region of the rat brain glycine transporter GLYT2 gene: identification of a novel isoform Neuroscience Letters. 242: 25-28. PMID 9509996 DOI: 10.1016/S0304-3940(98)00037-8  0.396
1997 Poyatos I, Ponce J, Aragón C, Giménez C, Zafra F. The glycine transporter GLYT2 is a reliable marker for glycine-immunoreactive neurons. Molecular Brain Research. 49: 63-70. PMID 9387864 DOI: 10.1016/S0169-328X(97)00124-1  0.364
1997 Zafra F, Aragón C, Giménez C. Molecular biology of glycinergic neurotransmission. Molecular Neurobiology. 14: 117-142. PMID 9294860 DOI: 10.1007/Bf02740653  0.454
1997 Olivares L, Aragón C, Giménez C, Zafra F. Analysis of the Transmembrane Topology of the Glycine Transporter GLYT1 Journal of Biological Chemistry. 272: 1211-1217. PMID 8995423 DOI: 10.1074/Jbc.272.2.1211  0.404
1995 Gomeza J, Zafra F, Olivares L, Giménez C, Aragón C. Regulation by phorbol esters of the glycine transporter (GLYT1) in glioblastoma cells Biochimica Et Biophysica Acta. 1233: 41-46. PMID 7833348 DOI: 10.1016/0005-2736(94)00249-O  0.493
1995 Olivares L, Aragon C, Gimenez C, Zafra F. The role of N-glycosylation in the targeting and activity of the GLYT1 glycine transporter Journal of Biological Chemistry. 270: 9437-9442. PMID 7721869 DOI: 10.1074/Jbc.270.16.9437  0.481
1995 Zafra F, Gomeza J, Olivares L, Aragon C, Gimenez C. Regional distribution and developmental variation of the glycine transporters GLYT1 and GLYT2 in the rat CNS European Journal of Neuroscience. 7: 1342-1352. PMID 7582108 DOI: 10.1111/J.1460-9568.1995.Tb01125.X  0.512
1994 Núñez E, Aragón C. Structural analysis and functional role of the carbohydrate component of glycine transporter. The Journal of Biological Chemistry. 269: 16920-4. PMID 8207014  0.405
1994 Olivares L, Aragón C, Giménez C, Zafra F. Carboxyl terminus of the glycine transporter GLYT1 is necessary for correct processing of the protein. The Journal of Biological Chemistry. 269: 28400-4. PMID 7961780  0.464
1994 Zafra F, Aragon C, Gimenez C. Characteristics and regulation of proline transport in cultured glioblastoma cells Biochemical Journal. 302: 675-680. PMID 7945191 DOI: 10.1042/Bj3020675  0.472
1994 Casado M, Bendahan A, Zafra F, Danbolt NC, Aragón C, Giménez C, Kanner BI. Phosphorylation and modulation of brain glutamate transporters by protein kinase C. The Journal of Biological Chemistry. 268: 27313-7. PMID 7903307  0.401
1993 Lopez-Corcuera B, Alcantara R, Vazquez J, Aragon C. Hydrodynamic properties and immunological identification of the sodium- and chloride-coupled glycine transporter Journal of Biological Chemistry. 268: 2239-2243. PMID 8420992  0.388
1992 Gomeza J, Aragón C, Giménez C. High-affinity transport of choline and amino acid neurotransmitters in synaptosomes from brain regions after lesioning the nucleus basalis magnocellularis of young and aged rats. Neurochemical Research. 17: 345-350. PMID 1355270 DOI: 10.1007/Bf00974576  0.332
1992 Alcántara R, Casado M, Olivares L, Giménez C, Aragón C. L-glutamate transporter derived from mRNAs of primary glial cultures: expression in Xenopus laevis oocytes. Brain Research. Molecular Brain Research. 15: 167-70. PMID 1331663 DOI: 10.1016/0169-328X(92)90166-9  0.399
1991 Gomeza J, Casado M, Gimenez C, Aragon C. Inhibition of high-affinity γ-aminobutyric acid uptake in primary astrocyte cultures by phorbol esters and phospholipase C Biochemical Journal. 275: 435-439. PMID 1902665 DOI: 10.1042/Bj2750435  0.409
1991 Lopez-Corcuera B, Vazquez J, Aragon C. Purification of the sodium- and chloride-coupled glycine transporter from central nervous system Journal of Biological Chemistry. 266: 24809-24814. PMID 1761575  0.43
1991 Casado M, Zafra F, Aragón C, Giménez C. Activation of high-affinity uptake of glutamate by phorbol esters in primary glial cell cultures Journal of Neurochemistry. 57: 1185-1190. PMID 1680157 DOI: 10.1111/J.1471-4159.1991.Tb08278.X  0.468
1991 Alcántara R, López-Corcuera B, Aragón C. Group-selective reagent modification of the sodium- and chloride-coupled glycine transporter under native and reconstituted conditions. Biochimica Et Biophysica Acta. 1067: 64-70. PMID 1651114 DOI: 10.1016/0005-2736(91)90026-5  0.533
1990 Zafra F, Alcantara R, Gomeza J, Aragon C, Gimenez C. Arachidonic acid inhibits glycine transport in cultured glial cells Biochemical Journal. 271: 237-242. PMID 2121132 DOI: 10.1042/Bj2710237  0.403
1989 Lopez-Corcuera B, Aragon C. Solubilization and reconstitution of the sodium-and-chloride-coupled glycine transporter from rat spinal cord European Journal of Biochemistry. 181: 519-524. PMID 2714298 DOI: 10.1111/J.1432-1033.1989.Tb14754.X  0.506
1989 Lopez-Corcuera B, Kanner BI, Aragón C. Reconstitution and partial purification of the sodium and chloride-coupled glycine transporter from rat spinal cord. Biochimica Et Biophysica Acta. 983: 247-52. PMID 2569327 DOI: 10.1016/0005-2736(89)90240-X  0.514
1986 Agullo L, Jimenez B, Aragon C, Gimenez C. β-Alanine transport in synaptic plasma membrane vesicles from rat brain. Efflux, exchange and stoichiometry European Journal of Biochemistry. 159: 611-617. PMID 3093232 DOI: 10.1111/J.1432-1033.1986.Tb09929.X  0.308
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