Year |
Citation |
Score |
2010 |
Takahashi Y, Hara Y, Imanaka M, Wanibuchi H, Tanaka K, Ishikawa T, Mori S, Fukusato T. No inhibitory effects of (-)-epigallocatechin gallate and lycopene on spontaneous hepatotumorigenesis in C3H/HeN mice. Fukushima Journal of Medical Science. 56: 17-27. PMID 21485652 DOI: 10.5387/Fms.56.17 |
0.385 |
|
2004 |
Nakatsuru Y, Wakabayashi K, Fujii-Kuriyama Y, Ishikawa T, Kusama K, Ide F. Dibenzo[A,L]pyrene-induced genotoxic and carcinogenic responses are dramatically suppressed in aryl hydrocarbon receptor-deficient mice. International Journal of Cancer. 112: 179-83. PMID 15352028 DOI: 10.1002/Ijc.20365 |
0.379 |
|
2004 |
Ide F, Suka N, Kitada M, Sakashita H, Kusama K, Ishikawa T. Skin and salivary gland carcinogenicity of 7,12-dimethylbenz[a]anthracene is equivalent in the presence or absence of aryl hydrocarbon receptor. Cancer Letters. 214: 35-41. PMID 15331171 DOI: 10.1016/J.Canlet.2004.04.014 |
0.392 |
|
2004 |
Ishikawa T, Zhang SS, Qin X, Takahashi Y, Oda H, Nakatsuru Y, Ide F. DNA repair and cancer: lessons from mutant mouse models. Cancer Science. 95: 112-7. PMID 14965359 DOI: 10.1111/J.1349-7006.2004.Tb03190.X |
0.666 |
|
2003 |
Ide F, Kitada M, Sakashita H, Kusama K, Tanaka K, Ishikawa T. p53 haploinsufficiency profoundly accelerates the onset of tongue tumors in mice lacking the xeroderma pigmentosum group A gene. The American Journal of Pathology. 163: 1729-33. PMID 14578172 DOI: 10.1016/S0002-9440(10)63531-6 |
0.401 |
|
2002 |
Takahashi Y, Nakatsuru Y, Zhang S, Shimizu Y, Kume H, Tanaka K, Ide F, Ishikawa T. Enhanced spontaneous and aflatoxin-induced liver tumorigenesis in xeroderma pigmentosum group A gene-deficient mice. Carcinogenesis. 23: 627-33. PMID 11960916 DOI: 10.1093/Carcin/23.4.627 |
0.408 |
|
2001 |
Tsuzuki T, Egashira A, Igarashi H, Iwakuma T, Nakatsuru Y, Tominaga Y, Kawate H, Nakao K, Nakamura K, Ide F, Kura S, Nakabeppu Y, Katsuki M, Ishikawa T, Sekiguchi M. Spontaneous tumorigenesis in mice defective in the MTH1 gene encoding 8-oxo-dGTPase Proceedings of the National Academy of Sciences of the United States of America. 98: 11456-11461. PMID 11572992 DOI: 10.1073/Pnas.191086798 |
0.42 |
|
2001 |
Ishikawa T, Ide F, Qin X, Zhang S, Takahashi Y, Sekiguchi M, Tanaka K, Nakatsuru Y. Importance of DNA repair in carcinogenesis: evidence from transgenic and gene targeting studies. Mutation Research. 477: 41-49. PMID 11376685 DOI: 10.1016/S0027-5107(01)00094-X |
0.436 |
|
2001 |
Ide F, Oda H, Nakatsuru Y, Kusama K, Sakashita H, Tanaka K, Ishikawa T. Xeroderma pigmentosum group A gene action as a protection factor against 4-nitroquinoline 1-oxide-induced tongue carcinogenesis. Carcinogenesis. 22: 567-572. PMID 11285190 DOI: 10.1093/Carcin/22.4.567 |
0.447 |
|
2000 |
Wang XJ, Yuan SL, Li CP, Iida N, Oda H, Aiso S, Ishikawa T. Infrequent p53 gene mutation and expression of the cardia adenocarcinomas from a high-incidence area of Southwest China. World Journal of Gastroenterology. 6: 750-753. PMID 11819688 DOI: 10.3748/Wjg.V6.I5.750 |
0.307 |
|
2000 |
Qin X, Zhang S, Matsukuma S, Zarkovic M, Shimizu S, Ishikawa T, Nakatsuru Y. Protection against malignant progression of spontaneously developing liver tumors in transgenic mice expressing O6-methylguanine-DNA methyltransferase Japanese Journal of Cancer Research. 91: 1085-1089. PMID 11092970 DOI: 10.1111/J.1349-7006.2000.Tb00888.X |
0.445 |
|
2000 |
Ise K, Nakamura K, Nakao K, Shimizu S, Harada H, Ichise T, Miyoshi J, Gondo Y, Ishikawa T, Aiba A, Katsuki M. Targeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesis. Oncogene. 19: 2951-2956. PMID 10871846 DOI: 10.1038/Sj.Onc.1203600 |
0.326 |
|
2000 |
Shindo T, Kurihara H, Kuno K, Yokoyama H, Wada T, Kurihara Y, Imai T, Wang Y, Ogata M, Nishimatsu H, Moriyama N, Oh-hashi Y, Morita H, Ishikawa T, Nagai R, et al. ADAMTS-1: a metalloproteinase-disintegrin essential for normal growth, fertility, and organ morphology and function. Journal of Clinical Investigation. 105: 1345-1352. PMID 10811842 DOI: 10.1172/Jci8635 |
0.316 |
|
2000 |
Ide F, Iida N, Nakatsuru Y, Oda H, Nikaido O, Ishikawa T. In vivo detection of ultraviolet photoproducts and their repair in purkinje cells. Laboratory Investigation. 80: 465-470. PMID 10780663 DOI: 10.1038/Labinvest.3780052 |
0.348 |
|
2000 |
Nakatsuru Y, Minami K, Yoshikawa A, Zhu J, Oda H, Masahito P, Okamoto N, Nakamura Y, Ishikawa T. Eel WT1 sequence and expression in spontaneous nephroblastomas in Japanese eel. Gene. 245: 245-251. PMID 10717475 DOI: 10.1016/S0378-1119(00)00016-0 |
0.359 |
|
2000 |
Kawate H, Itoh R, Sakumi K, Nakabeppu Y, Tsuzuki T, Ide F, Ishikawa T, Noda T, Nawata H, Sekiguchi M. A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice Carcinogenesis. 21: 301-305. PMID 10657972 DOI: 10.1093/Carcin/21.2.301 |
0.428 |
|
2000 |
Shimizu Y, Nakatsuru Y, Ichinose M, Takahashi Y, Kume H, Mimura J, Fujii-Kuriyama Y, Ishikawa T. Benzo[a]pyrene carcinogenicity is lost in mice lacking the aryl hydrocarbon receptor Proceedings of the National Academy of Sciences of the United States of America. 97: 779-782. PMID 10639156 DOI: 10.1073/Pnas.97.2.779 |
0.405 |
|
2000 |
Honda H, Ushijima T, Wakazono K, Oda H, Tanaka Y, Aizawa S, Ishikawa T, Yazaki Y, Hirai H. Acquired loss of p53 induces blastic transformation in p210bcr/abl-expressing hematopoietic cells: a transgenic study for blast crisis of human CML Blood. 95: 1144-1150. DOI: 10.1182/Blood.V95.4.1144.004K04_1144_1150 |
0.321 |
|
2000 |
Ide F, Iida N, Nakatsuru Y, Oda H, Tanaka K, Ishikawa T. Mice deficient in the nucleotide excision repair gene XPA have elevated sensitivity to benzo[a]pyrene induction of lung tumors. Carcinogenesis. 21: 1263-1265. DOI: 10.1093/Carcin/21.6.1263 |
0.398 |
|
1999 |
Shimizu Y, Zhu J, Han F, Ishikawa T, Oda H. Different frequencies of p53 codon-249 hot-spot mutations in hepatocellular carcinomas in Jiang-su province of China. International Journal of Cancer. 82: 187-190. PMID 10389750 DOI: 10.1002/(Sici)1097-0215(19990719)82:2<187::Aid-Ijc6>3.0.Co;2-1 |
0.343 |
|
1999 |
Nozawa H, Oda E, Nakao K, Ishihara M, Ueda S, Yokochi T, Ogasawara K, Nakatsuru Y, Shimizu S, Ohira Y, Hioki K, Aizawa S, Ishikawa T, Katsuki M, Muto T, et al. Loss of transcription factor IRF-1 affects tumor susceptibility in mice carrying the Ha-ras transgene or nullizygosity for p53 Genes & Development. 13: 1240-1245. PMID 10346812 DOI: 10.1101/Gad.13.10.1240 |
0.401 |
|
1999 |
Imai Y, Morishita S, Ikeda Y, Toyoda M, Ashizawa T, Yamamoto K, Inoue T, Ishikawa T. Immunohistochemical and molecular analysis of giant cell carcinoma of the pancreas: a report of three cases. Pancreas. 18: 308-315. PMID 10206490 DOI: 10.1097/00006676-199904000-00013 |
0.347 |
|
1999 |
Honda H, Inaba T, Suzuki T, Oda H, Ebihara Y, Tsuiji K, Nakahata T, Ishikawa T, Yazaki Y, Hirai H. Expression of E2A-HLF Chimeric Protein Induced T-Cell Apoptosis, B-Cell Maturation Arrest, and Development of Acute Lymphoblastic Leukemia Blood. 93: 2780-2790. DOI: 10.1182/Blood.V93.9.2780.409A47_2780_2790 |
0.36 |
|
1998 |
Imai Y, Inoue T, Ishikawa T. Mutations of the human MUT S homologue 6 gene in ampullary carcinoma and gastric cancer. International Journal of Cancer. 78: 576-580. PMID 9808525 DOI: 10.1002/(Sici)1097-0215(19981123)78:5<576::Aid-Ijc8>3.0.Co;2-5 |
0.334 |
|
1998 |
Chen T, Yamamoto S, Kitano M, Murai T, Wanibuchi H, Matsukuma S, Nakatsuru Y, Ishikawa T, Fukushima S. Possible rare involvement of O6-methylguanine formation as a significant mutational factor in mouse urinary bladder carcinogenesis models. Teratogenesis Carcinogenesis and Mutagenesis. 18: 101-110. PMID 9728794 DOI: 10.1002/(Sici)1520-6866(1998)18:3<101::Aid-Tcm1>3.0.Co;2-K |
0.397 |
|
1998 |
Tsurutani N, Oda H, Nakatsuru Y, Imai Y, Zhang S, Ueno Y, Ishikawa T. cDNA cloning and developmental expression of the porcine homologue of WT1. Gene. 211: 215-220. PMID 9602131 DOI: 10.1016/S0378-1119(98)00112-7 |
0.351 |
|
1998 |
Imai Y, Tsurutani N, Oda H, Inoue T, Ishikawa T. Genetic instability and mutation of the TGF-β-receptor-II gene in ampullary carcinomas International Journal of Cancer. 76: 407-411. PMID 9579579 DOI: 10.1002/(Sici)1097-0215(19980504)76:3<407::Aid-Ijc19>3.0.Co;2-7 |
0.309 |
|
1998 |
Honda H, Oda H, Suzuki T, Takahashi T, Witte ON, Ozawa K, Ishikawa T, Yazaki Y, Hirai H. Development of Acute Lymphoblastic Leukemia and Myeloproliferative Disorder in Transgenic Mice Expressing p210bcr/abl: A Novel Transgenic Model for Human Ph1-Positive Leukemias Blood. 91: 2067-2075. DOI: 10.1182/Blood.V91.6.2067.2067_2067_2075 |
0.329 |
|
1997 |
Imai Y, Tsurutani N, Oda H, Nakatsuru Y, Inoue T, Ishikawa T. p16INK4 gene mutations are relatively frequent in ampullary carcinomas. Japanese Journal of Cancer Research. 88: 941-946. PMID 9414654 DOI: 10.1111/J.1349-7006.1997.Tb00312.X |
0.357 |
|
1997 |
Maemura K, Kurihara H, Kurihara Y, Oda H, Ishikawa T, Copeland NG, Gilbert DJ, Jenkins NA, Yazaki Y. Sequence analysis, chromosomal location, and developmental expression of the mouse preproendothelin-1 gene. Genomics. 31: 177-84. PMID 8824799 DOI: 10.1006/Geno.1996.0029 |
0.319 |
|
1996 |
Imai Y, Oda H, Arai M, Shimizu S, Nakatsuru Y, Inoue T, Ishikawa T. Mutational Analysis of the p53 and K-ras Genes and Allelotype Study of the Rb-1 Gene for Investigating the Pathogenesis of Combined Hepatocellular-Cholangiocellular Carcinomas Japanese Journal of Cancer Research. 87: 1056-1062. PMID 8957064 DOI: 10.1111/J.1349-7006.1996.Tb03110.X |
0.303 |
|
1996 |
Tsuzuki T, Kunihiko S, Shiraishi A, Kawate H, Igarashi H, Iwakuma T, Tominaga Y, Zhang S, Shimizu S, Ishikawa T, Nakamura K, Nakao K, Katsuki M, Sekiguchi M. Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent. Carcinogenesis. 17: 1215-1220. PMID 8681434 DOI: 10.1093/Carcin/17.6.1215 |
0.423 |
|
1995 |
Oda H, Nakatsuru Y, Imai Y, Sugimura H, Ishikawa T. A mutational hot spot in the p53 gene is associated with hepatoblastomas International Journal of Cancer. 60: 786-790. PMID 7896446 DOI: 10.1002/Ijc.2910600610 |
0.325 |
|
1995 |
Imal Y, Oda H, Nakatsuru Y, Ishikawa T. A polymorphism at codon 160 of human O6 methylguanine-DNA methyltransferase gene in young patients with adult type cancers and functional assay Carcinogenesis. 16: 2441-2445. PMID 7586149 DOI: 10.1093/Carcin/16.10.2441 |
0.382 |
|
1994 |
Nakatsuru Y, Tsuchiya E, Nakagawa K, Nemoto N, Oda H, Ishikawa T. O6-methylguanine-dna methyltransferase activity in the human lung persists with advancing age Gerontology. 40: 3-9. PMID 7926865 DOI: 10.1159/000213620 |
0.325 |
|
1993 |
Nakatsuru Y, Matsukuma S, Nemoto N, Sugano H, Sekiguchi M, Ishikawa T. O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis Proceedings of the National Academy of Sciences of the United States of America. 90: 6468-6472. PMID 8341657 DOI: 10.1073/Pnas.90.14.6468 |
0.432 |
|
1993 |
Matsumoto J, Akiyama T, Nemoto N, Masahito P, Ishikawa T. Appearance of Tumorous Phenotypes in Goldfish Erythrophores Transfected with ras, src, and myc Oncogenes and Spontaneous Differentiation of the Transformants In Vitro Journal of Investigative Dermatology. 100: 214-221. DOI: 10.1038/Jid.1993.79 |
0.318 |
|
1991 |
Nakatsuru Y, Matsukuma S, Sekiguchi M, Ishikawa T. Characterization of O6-methylguanine-DNA methyltransferase in transgenic mice introduced with the E. coli ada gene. Mutation Research-Dna Repair. 254: 225-230. PMID 2052012 DOI: 10.1016/0921-8777(91)90060-3 |
0.383 |
|
1991 |
Nemoto N, Sakurai J, Tazawa A, Ishikawa T. Regulation of mouse P1450 gene expression in monolayer-cultured hepatocytes from responsive and non-responsive strains Carcinogenesis. 12: 623-629. PMID 1849469 DOI: 10.1093/Carcin/12.4.623 |
0.305 |
|
1990 |
Qin X, Nakatsuru Y, Kohyama K, Ishikawa T. DNA adduct formation and unscheduled DNA synthesis in rat esophages in vivo after treatment with N-methyl-N-nitrosourea Carcinogenesis. 11: 235-238. PMID 2302750 DOI: 10.1093/Carcin/11.2.235 |
0.342 |
|
1990 |
Qin X, Nakatsuru Y, Tada M, Ishikawa T. Species and organ differences in DNA adduct formation and repair after treatment with 4-hydroxyaminoquinoline 1-oxide. Japanese Journal of Cancer Research. 81: 613-619. PMID 2119365 DOI: 10.1111/J.1349-7006.1990.Tb02617.X |
0.352 |
|
1990 |
Nakatsuru Y, Qin X, Masahito P, Ishikawa T. Immunological detection of in vivo aflatoxin B1-DNA adduct formation in rats, rainbow trout and coho salmon. Carcinogenesis. 11: 1523-1526. PMID 2119257 DOI: 10.1093/Carcin/11.9.1523 |
0.343 |
|
1989 |
Nakatsuru Y, Aoki K, Ishikawa T. Age and strain dependence of O6-methylguanine DNA methyltransferase activity in mice Mutation Research. 219: 51-56. PMID 2911271 DOI: 10.1016/0921-8734(89)90040-4 |
0.34 |
|
1989 |
Matsukuma S, Nakatsuru Y, Nakagawa K, Utakoji T, Sugano H, Kataoka H, Sekiguchi M, Ishikawa T. Enhanced O6-methylguanine-DNA methyltransferase activity in transgenic mice containing an integrated E. coli ada repair gene. Mutation Research. 218: 197-206. PMID 2530449 DOI: 10.1016/0921-8777(89)90004-9 |
0.401 |
|
1989 |
Masahito P, Aoki K, Egami N, Ishikawa T, Sugano H. Life-span studies on spontaneous tumor development in the medaka (Oryzias latipes). Japanese Journal of Cancer Research : Gann. 80: 1058-65. PMID 2514168 DOI: 10.1111/J.1349-7006.1989.Tb02259.X |
0.319 |
|
1989 |
Nakagawa K, Nakatsuru Y, Ishikawa T. Immunohistochemical detection of carcinogen-DNA adducts and DNA repair in mouse skin Journal of Investigative Dermatology. 92: 275. DOI: 10.1038/Jid.1989.81 |
0.364 |
|
1989 |
Masahito P, Ishikawa T, Sugano H. Pigment Cells and Pigment Cell Tumors in Fish Journal of Investigative Dermatology. 92: 266-270. DOI: 10.1038/Jid.1989.79 |
0.35 |
|
1988 |
Nemoto N, Nakatsuru Y, Nakagawa K, Tazawa A, Ishikawa T. Immunohistochemical detection of anti-(±)-trans-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydrobenzo(a)pyrene-bound adduct in nuclei of cultured HeLa cells and mouse lung tissue Journal of Cancer Research and Clinical Oncology. 114: 225-230. PMID 3133374 DOI: 10.1007/Bf00405826 |
0.326 |
|
1988 |
Nakagawa K, Tada M, Morita T, Utsunomiya J, Ishikawa T. Immunohistochemical Detection of 4–Hydroxyaminoquinoline 1–Oxide—DNA Adducts in Mouse Tissues In Vivo Journal of the National Cancer Institute. 80: 419-425. PMID 3130487 DOI: 10.1093/Jnci/80.6.419 |
0.375 |
|
1986 |
Ishikawa T, Masahito P, Nemoto N, Matsumoto J, Shima A. Spontaneous Neurinoma in an African Lungfish, Protopterus annectens, and DNA Repair Studies on Normal and Neoplastic Tissues Journal of the National Cancer Institute. 77: 521-528. DOI: 10.1093/Jnci/77.2.521 |
0.374 |
|
1985 |
Masahito P, Ishikawa T, Yanagisawa A, Sugano H, Ikeda K. Neurogenic Tumors in Coho Salmon (Oncorhynchus kisutch) Reared in Well Water in Japan Journal of the National Cancer Institute. 75: 779-790. DOI: 10.1093/Jnci/75.4.779 |
0.309 |
|
1984 |
Masahito P, Ishikawa T, Takayama S, Sugimura H. Gonadal neoplasms in largemouth bass, Micropterus salmoides and Japanese dace (ugui), Tribolodon hakonensis. Gann Japanese Journal of Cancer Research. 75: 776-783. DOI: 10.20772/Cancersci1959.75.9_776 |
0.307 |
|
1983 |
Matsumoto J, Lynch TJ, Grabowski S, Richards CM, Lo SL, Clark C, Kern D, Taylor JD, Tchen TT, Ishikawa T, Masahito P, Takayama S. Fish tumor pigment cells: Differentiation and comparison to their normal counterparts Integrative and Comparative Biology. 23: 569-580. DOI: 10.1093/Icb/23.3.569 |
0.322 |
|
1982 |
Ide F, Ishikawa T, Takagi M, Umemura S, Takayama S. Unscheduled DNA Synthesis in Human Oral Mucosa Treated With Chemical Carcinogens in Short-Term Organ Culture Journal of the National Cancer Institute. 69: 557-563. DOI: 10.1093/Jnci/69.3.557 |
0.32 |
|
1981 |
Ide F, Ishikawa T, Takayama S. Detection of chemical carcinogens by assay of unscheduled DNA synthesis in rat tracheal epithelium in short-term organ culture Journal of Cancer Research and Clinical Oncology. 102: 115-126. PMID 7338530 DOI: 10.1007/Bf00410663 |
0.318 |
|
1981 |
Ide F, Ishikawa T, Takayama S, Umemura S. Autoradiographic demonstration of unscheduled DNA synthesis in oral tissues treated with chemical carcinogens in short‐term organ culture Journal of Oral Pathology & Medicine. 10: 113-123. PMID 6792332 DOI: 10.1111/J.1600-0714.1981.Tb01256.X |
0.302 |
|
1978 |
Ishikawa T, Takayama S, Kitagawa T. DNA Repair Synthesis in Rat Retinal Ganglion Cells Treated With Chemical Carcinogens or Ultraviolet Light In Vitro, With Special Reference to Aging and Repair Level Journal of the National Cancer Institute. 61: 1101-1105. DOI: 10.1093/Jnci/61.4.1101 |
0.313 |
|
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