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Year Citation  Score
2018 Mallet RT, Manukhina EB, Ruelas SS, Caffrey JL, Downey HF. Cardioprotection by intermittent hypoxia conditioning: evidence, mechanisms, and therapeutic potential. American Journal of Physiology. Heart and Circulatory Physiology. 315: H216-H232. PMID 29652543 DOI: 10.1152/ajpheart.00060.2018  0.415
2018 Lazuko SS, Kuzhel OP, Belyaeva LE, Manukhina EB, Downey HF, Fred Downey H, Tseilikman OB, Komelkova MV, Tseilikman VE. Posttraumatic Stress Disorder Disturbs Coronary Tone and Its Regulatory Mechanisms. Cellular and Molecular Neurobiology. 38: 209-217. PMID 28676988 DOI: 10.1007/s10571-017-0517-x  0.302
2013 Manukhina EB, Terekhina OL, Belkina LM, Abramochkin DV, Budanova OP, Mashina SY, Smirin BV, Yakunina EB, Downey HF. [Vasoprotective effect of adaptation to hypoxia in myocardial ischemia and reperfusion injury]. Patologicheskaia Fiziologiia I Eksperimental'Naia Terapiia. 26-31. PMID 24640770  0.334
2013 Manukhina EB, Belkina LM, Terekhina OL, Abramochkin DV, Smirnova EA, Budanova OP, Mallet RT, Downey HF. Normobaric, intermittent hypoxia conditioning is cardio- and vasoprotective in rats. Experimental Biology and Medicine (Maywood, N.J.). 238: 1413-20. PMID 24189016 DOI: 10.1177/1535370213508718  0.374
2008 Ryou MG, Sun J, Oguayo KN, Manukhina EB, Downey HF, Mallet RT. Hypoxic conditioning suppresses nitric oxide production upon myocardial reperfusion. Experimental Biology and Medicine (Maywood, N.J.). 233: 766-74. PMID 18408142 DOI: 10.3181/0710-RM-282  0.413
2008 Setty S, Zong P, Sun W, Tune JD, Downey HF. Hypoxia-induced vasodilation in the right coronary circulation of conscious dogs: role of adrenergic activation. Autonomic Neuroscience : Basic & Clinical. 138: 76-82. PMID 18055275 DOI: 10.1016/J.Autneu.2007.10.004  0.804
2006 Mallet RT, Ryou MG, Williams AG, Howard L, Downey HF. Beta1-Adrenergic receptor antagonism abrogates cardioprotective effects of intermittent hypoxia. Basic Research in Cardiology. 101: 436-46. PMID 16705468 DOI: 10.1007/s00395-006-0599-y  0.319
2005 Knott EM, Tune JD, Stoll ST, Downey HF. Increased lymphatic flow in the thoracic duct during manipulative intervention. The Journal of the American Osteopathic Association. 105: 447-56. PMID 16314677 DOI: 10.7556/Jaoa.2005.105.10.447  0.609
2005 Zong P, Tune JD, Downey HF. Mechanisms of oxygen demand/supply balance in the right ventricle. Experimental Biology and Medicine (Maywood, N.J.). 230: 507-19. PMID 16118400 DOI: 10.1177/153537020523000801  0.737
2005 Martinez RR, Setty S, Zong P, Tune JD, Downey HF. Nitric oxide contributes to right coronary vasodilation during systemic hypoxia. American Journal of Physiology. Heart and Circulatory Physiology. 288: H1139-46. PMID 15513958 DOI: 10.1152/Ajpheart.01139.2003  0.792
2004 Setty S, Tune JD, Downey HF. Nitric oxide contributes to oxygen demand-supply balance in hypoperfused right ventricle. Cardiovascular Research. 64: 431-6. PMID 15537496 DOI: 10.1016/J.Cardiores.2004.07.021  0.738
2004 Zong P, Setty S, Sun W, Martinez R, Tune JD, Ehrenburg IV, Tkatchouk EN, Mallet RT, Downey HF. Intermittent hypoxic training protects canine myocardium from infarction. Experimental Biology and Medicine (Maywood, N.J.). 229: 806-12. PMID 15337835 DOI: 10.1177/153537020422900813  0.775
2004 Zong P, Sun W, Setty S, Tune JD, Downey HF. Alpha-adrenergic vasoconstrictor tone limits right coronary blood flow in exercising dogs. Experimental Biology and Medicine (Maywood, N.J.). 229: 312-22. PMID 15044714 DOI: 10.1177/153537020422900405  0.784
2004 Setty S, Sun W, Martinez R, Downey HF, Tune JD. Alpha-adrenoceptor-mediated coronary vasoconstriction is augmented during exercise in experimental diabetes mellitus. Journal of Applied Physiology (Bethesda, Md. : 1985). 97: 431-8. PMID 14978008 DOI: 10.1152/Japplphysiol.01122.2003  0.796
2002 Zong P, Tune JD, Setty S, Downey HF. Endogenous nitric oxide regulates right coronary blood flow during acute pulmonary hypertension in conscious dogs. Basic Research in Cardiology. 97: 392-8. PMID 12200639 DOI: 10.1007/S003950200048  0.784
2002 Bian X, Downey HF. Enhanced intra-aortic balloon pump: Markedly improved systemic hemodynamics and cardiac function in canines with severe, acute left ventricular failure Artificial Organs. 26: 727-733. PMID 12139502 DOI: 10.1046/j.1525-1594.2002.06931_6.x  0.427
2002 Tune JD, Yeh C, Setty S, Zong P, Downey HF. Coronary blood flow control is impaired at rest and during exercise in conscious diabetic dogs. Basic Research in Cardiology. 97: 248-57. PMID 12061395 DOI: 10.1007/S003950200018  0.796
2002 Tune JD, Yeh C, Setty S, Downey HF. ATP-dependent K(+) channels contribute to local metabolic coronary vasodilation in experimental diabetes. Diabetes. 51: 1201-7. PMID 11916945 DOI: 10.2337/Diabetes.51.4.1201  0.78
2002 Setty S, Tune JD, Downey HF. Nitric oxide modulates right ventricular flow and oxygen consumption during norepinephrine infusion. American Journal of Physiology. Heart and Circulatory Physiology. 282: H696-703. PMID 11788420 DOI: 10.1152/Ajpheart.00398.2001  0.8
2001 Setty S, Bian X, Tune JD, Downey HF. Endogenous nitric oxide modulates myocardial oxygen consumption in canine right ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 281: H831-7. PMID 11454588 DOI: 10.1152/Ajpheart.2001.281.2.H831  0.739
2001 Hart BJ, Bian X, Gwirtz PA, Setty S, Downey HF. Right ventricular oxygen supply/demand balance in exercising dogs. American Journal of Physiology-Heart and Circulatory Physiology. 281. PMID 11454587 DOI: 10.1152/Ajpheart.2001.281.2.H823  0.373
2000 Yi KD, Downey HF, Bian X, Fu M, Mallet RT. Dobutamine enhances both contractile function and energy reserves in hypoperfused canine right ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 279: H2975-85. PMID 11087255 DOI: 10.1152/ajpheart.2000.279.6.H2975  0.319
2000 Hart BJ, Bian X, Mallet RT, Downey HF. Hyperlipidemia with hypoglycemia reduces myocardial oxygen utilization efficiency but not contractile function during coronary hypoperfusion. Journal of Molecular and Cellular Cardiology. 32: 1539-52. PMID 10900179 DOI: 10.1006/jmcc.2000.1190  0.422
2000 Bian X, Fu M, Mallet RT, Bünger R, Downey HF. Myocardial oxygen consumption modulates adenosine formation by canine right ventricle in absence of hypoxia. Journal of Molecular and Cellular Cardiology. 32: 345-54. PMID 10731434 DOI: 10.1006/jmcc.1999.1077  0.448
1999 Hart BJ, Bian X, Williams AG, Downey HF. A method for producing regional hypoglycemia in blood perfused tissue. Molecular and Cellular Biochemistry. 200: 177-81. PMID 10569198  0.373
1999 Bian X, Downey HF. Right coronary pressure modulates right ventricular systolic stiffness and oxygen consumption Cardiovascular Research. 42: 80-86. PMID 10434998 DOI: 10.1016/S0008-6363(98)00288-0  0.455
1999 Bian X, Hart BJ, Williams AG, Downey HF. A method for collecting right coronary venous blood samples from conscious dogs. The American Journal of Physiology. 276: H1086-90. PMID 10070095  0.44
1998 Tune JD, Mallet RT, Downey HF. Insulin improves contractile function during moderate ischemia in canine left ventricle. American Journal of Physiology. Heart and Circulatory Physiology. 274: H1574-H1581. PMID 29586499 DOI: 10.1152/ajpheart.1998.274.5.H1574  0.622
1998 He MX, Downey HF. Downregulation of ventricular contractile function during early ischemia is flow but not pressure dependent. The American Journal of Physiology. 275: H1520-3. PMID 9815056 DOI: 10.1152/ajpheart.1998.275.5.H1520  0.331
1998 Tune JD, Mallet RT, Downey HF. Insulin improves cardiac contractile function and oxygen utilization efficiency during moderate ischemia without compromising myocardial energetics. Journal of Molecular and Cellular Cardiology. 30: 2025-35. PMID 9799656 DOI: 10.1006/Jmcc.1998.0763  0.631
1998 Itoya M, Morrison JD, Downey HF. Effect of ethanol on myocardial infarct size in a canine model of coronary artery occlusion-reperfusion. Molecular and Cellular Biochemistry. 186: 35-41. PMID 9774183  0.369
1998 Bian X, Williams AG, Gwirtz PA, Downey HF. Right coronary autoregulation in conscious, chronically instrumented dogs. The American Journal of Physiology. 275: H169-75. PMID 9688910 DOI: 10.1152/Ajpheart.1998.275.1.H169  0.395
1998 Tune JD, Mallet RT, Downey HF. Insulin improves contractile function during moderate ischemia in canine left ventricle. The American Journal of Physiology. 274: H1574-81. PMID 9612366 DOI: 10.1152/Ajpheart.1998.274.5.H1574  0.627
1997 Yu Y, Tune JD, Downey HF. Elevated right atrial pressure does not reduce collateral blood flow to ischemic myocardium. American Journal of Physiology. Heart and Circulatory Physiology. 273: H2296-H2303. PMID 29586485 DOI: 10.1152/ajpheart.1997.273.5.H2296  0.7
1997 Yu Y, Tune JD, Downey HF. Elevated right atrial pressure does not reduce collateral blood flow to ischemic myocardium. The American Journal of Physiology. 273: H2296-303. PMID 9374766 DOI: 10.1152/Ajpheart.1997.273.5.H2296  0.71
1997 He MX, Wang S, Downey HF. Correlation between myocardial contractile force and cytosolic inorganic phosphate during early ischemia. The American Journal of Physiology. 272: H1333-41. PMID 9087609 DOI: 10.1152/ajpheart.1997.272.3.H1333  0.315
1996 Mallet RT, Lee SC, Downey HF. Endogenous adenosine increases O2 utilisation efficiency in isoprenaline-stimulated canine myocardium. Cardiovascular Research. 31: 102-16. PMID 8849594  0.317
1996 Itoya M, Mallet RT, Gao ZP, Williams AG, Downey HF. Stability of high-energy phosphates in right ventricle: myocardial energetics during right coronary hypotension. The American Journal of Physiology. 271: H320-8. PMID 8760191 DOI: 10.1152/ajpheart.1996.271.1.H320  0.41
1994 Bai XJ, Iwamoto T, Williams AG, Fan WL, Downey HF. Coronary pressure-flow autoregulation protects myocardium from pressure-induced changes in oxygen consumption. The American Journal of Physiology. 266: H2359-68. PMID 8023997 DOI: 10.1152/ajpheart.1994.266.6.H2359  0.468
1994 Iwamoto T, Bai XJ, Downey HF. Coronary perfusion related changes in myocardial contractile force and systolic ventricular stiffness. Cardiovascular Research. 28: 1331-6. PMID 7954641 DOI: 10.1093/cvr/28.9.1331  0.415
1994 Cicutti N, Rakusan K, Downey HF. Coronary artery occlusion extends perfusion territory boundaries through microvascular collaterals. Basic Research in Cardiology. 89: 427-37. PMID 7702535 DOI: 10.1007/BF00788280  0.364
1993 Gaugl JF, Williams AG, Downey HF. Arteriovenous-shunt-mediated increase in venous return causes apparent right coronary arterial autoregulation. Cardiovascular Research. 27: 748-52. PMID 8348574 DOI: 10.1093/cvr/27.5.748  0.482
1993 Shizukuda Y, Iwamoto T, Mallet RT, Downey HF. Hypoxic preconditioning attenuates stunning caused by repeated coronary artery occlusions in dog heart. Cardiovascular Research. 27: 559-64. PMID 8324786 DOI: 10.1093/cvr/27.4.559  0.4
1992 Lee SC, Mallet RT, Shizukuda Y, Williams AG, Downey HF. Canine coronary vasodepressor responses to hypoxia are attenuated but not abolished by 8-phenyltheophylline. The American Journal of Physiology. 262: H955-60. PMID 1566915 DOI: 10.1152/ajpheart.1992.262.4.H955  0.411
1992 Cicutti N, Rakusan K, Downey HF. Colored microspheres reveal interarterial microvascular anastomoses in canine myocardium. Basic Research in Cardiology. 87: 400-9. PMID 1417709 DOI: 10.1007/BF00796525  0.301
1992 Gwirtz PA, Dodd-O JM, Downey HF, Mass HJ, Barron BA, Williams AG, Jones CE. Effects of a coronary alpha 1-constriction on transmural left ventricular flow and contractile function. The American Journal of Physiology. 262: H965-72. PMID 1348911  0.447
1989 Hengy B, Watanabe N, Williams AG, Downey HF. Does peripheral collateralization also cause collateralization in the canine heart? Clinical and Experimental Pharmacology & Physiology. 16: 429-32. PMID 2766583 DOI: 10.1111/j.1440-1681.1989.tb01581.x  0.439
1989 Murakami H, Kim SJ, Downey HF. Persistent right coronary flow reserve at low perfusion pressure. The American Journal of Physiology. 256: H1176-84. PMID 2705556 DOI: 10.1152/ajpheart.1989.256.4.H1176  0.495
1989 Watanabe N, Yonekura S, Williams AG, Scheel KW, Downey HF. Regression and recovery of well-developed coronary collateral function in canine hearts after aorta-coronary bypass. The Journal of Thoracic and Cardiovascular Surgery. 97: 286-96. PMID 2492626  0.46
1988 Crystal GJ, Downey HF. Perfusion with non-oxygenated Tyrode solution causes maximal coronary vasodilation in canine hearts. Clinical and Experimental Pharmacology & Physiology. 14: 851-7. PMID 3447793 DOI: 10.1111/j.1440-1681.1987.tb02421.x  0.502
1988 Yonekura S, Watanabe N, Downey HF. Transmural variation in autoregulation of right ventricular blood flow. Circulation Research. 62: 776-81. PMID 3349576 DOI: 10.1161/01.RES.62.4.776  0.361
1988 Downey HF, Merrill GF, Yonekura S, Watanabe N, Jones CE. Adenosine deaminase attenuates norepinephrine-induced coronary functional hyperemia. The American Journal of Physiology. 254: H417-24. PMID 3348422 DOI: 10.1152/ajpheart.1988.254.3.H417  0.308
1988 Downey HF, Murakami H, Kim SJ, Watanabe N, Yonekura S, Williams AG. Peripheral embolization provides evidence for microvascular collaterals in hearts with chronic coronary artery occlusion. Microcirculation, Endothelium, and Lymphatics. 4: 311-25. PMID 3231181  0.372
1988 Merrill GF, Downey HF, Yonekura S, Watanabe N, Jones CE. Adenosine deaminase attenuates canine coronary vasodilatation during regional non-ischaemic myocardial hypoxia. Cardiovascular Research. 22: 345-50. PMID 3191518 DOI: 10.1093/cvr/22.5.345  0.343
1987 Watanabe N, Yonekura S, Downey HF. Regional myocardial blood flow during cardiac tamponade in hearts with chronic coronary artery occlusion. Cardiovascular Research. 21: 530-6. PMID 3677142 DOI: 10.1093/CVR/21.7.530  0.463
1987 McAndrew JD, Downey HF. Blood flow to acutely ischaemic myocardium during pericardial tamponade: dominant influence of aortic blood pressure. Cardiovascular Research. 20: 822-7. PMID 3621283 DOI: 10.1093/cvr/20.11.822  0.374
1987 Yonekura S, Watanabe N, Caffrey JL, Gaugl JF, Downey HF. Mechanism of attenuated pressure-flow autoregulation in right coronary circulation of dogs. Circulation Research. 60: 133-41. PMID 3568284 DOI: 10.1161/01.RES.60.1.133  0.448
1986 Merrill GF, Downey HF, Jones CE. Adenosine deaminase attenuates canine coronary vasodilation during systemic hypoxia. The American Journal of Physiology. 250: H579-83. PMID 3963215 DOI: 10.1152/ajpheart.1986.250.4.H579  0.313
1984 Crystal GJ, Downey HF, Bashour FA. Persistent coronary vasodilation during long-term, supramaximal doses of adenosine. The American Journal of Physiology. 247: H869-73. PMID 6496766 DOI: 10.1152/AJPHEART.1984.247.5.H869  0.46
1984 DOWNEY H, BASHOUR F, WILLIAMS A. Myocardial oxygen supply and consumption during graded, regional, non-ischemic, myocardial hypoxia: Effect of elevated perfusion pressure* Journal of Molecular and Cellular Cardiology. 16: 16-16. DOI: 10.1016/S0022-2828(84)80079-6  0.32
1983 Crystal GJ, Downey HF, Bashour FA. Pressure-induced changes in coronary flow and volume during reperfusion in canine hearts. Clinical and Experimental Pharmacology & Physiology. 9: 485-94. PMID 7140016 DOI: 10.1111/j.1440-1681.1982.tb00822.x  0.454
1983 Downey HF, Crystal GJ, Bashour FA. Asynchronous transmural perfusion during coronary reactive hyperaemia. Cardiovascular Research. 17: 200-6. PMID 6871909 DOI: 10.1093/CVR/17.4.200  0.443
1983 Downey HF, Crystal GJ, Bashour FA. Regional myocardial blood flow during nicotine infusion after chronic coronary artery occlusion: effect of beta-adrenergic blockade. Journal of Cardiovascular Pharmacology. 5: 685-90. PMID 6193368 DOI: 10.1097/00005344-198307000-00025  0.398
1982 Downey HF, Crystal GJ, Bockman EL, Bashour FA. Nonischemic myocardial hypoxia: coronary dilation without increased tissue adenosine. The American Journal of Physiology. 243: H512-6. PMID 7124959 DOI: 10.1152/AJPHEART.1982.243.4.H512  0.437
1982 Crystal GJ, Downey HF, Bashour FA. Evaluation of noncoronary sources of left ventricular perfusion to intercoronary collateral-dependent myocardium due to chronic major vessel occlusion: absent contribution of luminal and extracardiac channels. American Heart Journal. 102: 841-5. PMID 7030041 DOI: 10.1016/0002-8703(81)90034-X  0.491
1981 Crystal GJ, Downey HF, Bashour FA. Small vessel and total coronary blood volume during intracoronary adenosine. The American Journal of Physiology. 241: H194-201. PMID 7270706 DOI: 10.1152/AJPHEART.1981.241.2.H194  0.429
1981 Downey HF, Crystal GJ, Bashour FA. Functional significance of microvascular collateral anastomoses after chronic coronary artery occlusion. Microvascular Research. 21: 212-22. PMID 7219201 DOI: 10.1016/0026-2862(81)90033-9  0.328
1981 Crystal GJ, Downey HF, Bashour FA. Myocardial oxygen consumption and blood flow during nicotine infusion: effect of combined alpha- and beta-adrenergic blockade. Journal of Cardiovascular Pharmacology. 3: 317-27. PMID 6166803 DOI: 10.1097/00005344-198103000-00010  0.465
1980 Boatwright RB, Downey HF, Bashour FA, Crystal GJ. Transmural variation in autoregulation of coronary blood flow in hyperperfused canine myocardium. Circulation Research. 47: 599-609. PMID 7408136 DOI: 10.1161/01.res.47.4.599  0.409
1979 Downey HF, Bashour FA, Jishi B, Parker PE. Arteriovenous shunts in dilated or reperfused canine coronary vasculature. Microvascular Research. 17: 22-6. PMID 459930 DOI: 10.1016/0026-2862(79)90004-9  0.363
1979 Crystal GJ, Boatwright RB, Downey HF, Bashour FA. Shunting of microspheres across the canine coronary circulation. The American Journal of Physiology. 236: H7-12. PMID 434177 DOI: 10.1152/AJPHEART.1979.236.1.H7  0.465
1979 Parker PE, Bashour FA, Downey HF, Boutros IS. Coronary reperfusion: effects of hyperosmotic mannitol. American Heart Journal. 97: 745-52. PMID 433751 DOI: 10.1016/0002-8703(79)90009-7  0.321
1979 Crystal GJ, Bashour FA, Downey HF, Parker PE. Myocardial blood flow and oxygen consumption during moderate cardiac tamponade: role of reflex vasoconstriction. Proceedings of the Society For Experimental Biology and Medicine. Society For Experimental Biology and Medicine (New York, N.Y.). 160: 65-8. PMID 419129 DOI: 10.3181/00379727-160-40390  0.376
1977 Parker PE, Bashour FA, Downey HF, Boutros IS. Coronary reperfusion: effects of vasodilators (papaverine and adenosine). American Heart Journal. 93: 66-72. PMID 831413 DOI: 10.1016/S0002-8703(77)80173-7  0.394
1977 Downey HF, Bashour CA, Boutros IS, Bashour FA, Parker PE. Regional myocardial blood flow during nicotine infusion: effects of beta adrenergic blockade, and acute coronary artery occlusion. The Journal of Pharmacology and Experimental Therapeutics. 202: 55-68. PMID 17730  0.387
1976 Parker PE, Bashour FA, Downey HF, Kechejian SJ, Williams AG. Coronary hemodynamics during reperfusion following acute coronary ligation in dogs. American Heart Journal. 90: 593-9. PMID 1190037 DOI: 10.1016/0002-8703(75)90223-9  0.458
1975 Downey HF, Bashour FA, Boatwright RB, Parker PE, Kechejian SJ. Uniformity of transmural perfusion in anesthetized dogs with maximally dilated coronary circulations. Circulation Research. 37: 111-7. PMID 1149181 DOI: 10.1161/01.RES.37.1.111  0.399
1975 Downey HF, Bashour FA, Parker PE, Bashour CA, Rutherford CS. Myocardial and total body extractions of radiorubidium in anesthetized dogs. Journal of Applied Physiology. 38: 31-2. PMID 1110239 DOI: 10.1152/JAPPL.1975.38.1.31  0.355
1974 Downey JM, Downey HF, Kirk ES. Effects of myocardial strains on coronary blood flow Circulation Research. 34: 286-292. PMID 4818755 DOI: 10.1161/01.RES.34.3.286  0.472
1974 Downey HF, Bashour FA, Stephens AJ, Kechejian SJ, Underwood RH. Transmural gradient of retrograde collateral blood flow in acutely ischemic canine myocardium Circulation Research. 35: 365-371. PMID 4424220 DOI: 10.1161/01.RES.35.3.365  0.4
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