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Uri Ben-David - Publications

Affiliations: 
Broad Institute (MIT/Harvard) 
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35 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Zerbib J, Ippolito MR, Eliezer Y, De Feudis G, Reuveni E, Savir Kadmon A, Martin S, Viganò S, Leor G, Berstler J, Muenzner J, Mülleder M, Campagnolo EM, Shulman ED, Chang T, ... ... Ben-David U, et al. Human aneuploid cells depend on the RAF/MEK/ERK pathway for overcoming increased DNA damage. Nature Communications. 15: 7772. PMID 39251587 DOI: 10.1038/s41467-024-52176-x  0.385
2024 Martin S, Scorzoni S, Cordone S, Mazzagatti A, Beznoussenko GV, Gunn AL, Di Bona M, Eliezer Y, Leor G, Ben-Yishay T, Loffreda A, Cancila V, Rainone MC, Ippolito MR, Martis V, ... ... Ben-David U, et al. A p62-dependent rheostat dictates micronuclei catastrophe and chromosome rearrangements. Science (New York, N.Y.). 385: eadj7446. PMID 39208097 DOI: 10.1126/science.adj7446  0.313
2024 Nair NU, Schaffer AA, Gertz EM, Cheng K, Zerbib J, Sahu AD, Leor G, Shulman ED, Aldape KD, Ben-David U, Ruppin E. Chromosome 7 gain compensates for chromosome 10 loss in glioma. Cancer Research. PMID 39078448 DOI: 10.1158/0008-5472.CAN-24-1366  0.306
2024 Jubran J, Slutsky R, Rozenblum N, Rokach L, Ben-David U, Yeger-Lotem E. Machine-learning analysis reveals an important role for negative selection in shaping cancer aneuploidy landscapes. Genome Biology. 25: 95. PMID 38622679 DOI: 10.1186/s13059-024-03225-7  0.363
2024 Nair NU, Schäffer AA, Gertz EM, Cheng K, Zerbib J, Sahu AD, Leor G, Shulman ED, Aldape KD, Ben-David U, Ruppin E. Chromosome 7 to the rescue: overcoming chromosome 10 loss in gliomas. Biorxiv : the Preprint Server For Biology. PMID 38313282 DOI: 10.1101/2024.01.17.576103  0.4
2023 Chang TG, Cao Y, Shulman ED, Ben-David U, Schäffer AA, Ruppin E. Optimizing cancer immunotherapy response prediction by tumor aneuploidy score and fraction of copy number alterations. Npj Precision Oncology. 7: 54. PMID 37270587 DOI: 10.1038/s41698-023-00408-6  0.33
2023 Prasad K, Ben-David U. A balancing act: how whole-genome doubling and aneuploidy interact in human cancer. Oncotarget. 14: 382-383. PMID 37185141 DOI: 10.18632/oncotarget.28374  0.374
2023 Garribba L, De Feudis G, Martis V, Galli M, Dumont M, Eliezer Y, Wardenaar R, Ippolito MR, Iyer DR, Tijhuis AE, Spierings DCJ, Schubert M, Taglietti S, Soriani C, Gemble S, ... ... Ben-David U, et al. Short-term molecular consequences of chromosome mis-segregation for genome stability. Nature Communications. 14: 1353. PMID 36906648 DOI: 10.1038/s41467-023-37095-7  0.412
2022 Hoge ACH, Getz M, Zimmer A, Ko M, Raz L, Beroukhim R, Golub TR, Ha G, Ben-David U. Publisher Correction: DNA-based copy number analysis confirms genomic evolution of PDX models. Npj Precision Oncology. 6: 50. PMID 35821277 DOI: 10.1038/s41698-022-00293-5  0.56
2022 Prasad K, Bloomfield M, Levi H, Keuper K, Bernhard SV, Baudoin NC, Leor G, Eliezer Y, Giam M, Wong CK, Rancati G, Storchová Z, Cimini D, Ben-David U. Whole-Genome Duplication Shapes the Aneuploidy Landscape of Human Cancers. Cancer Research. 82: 1736-1752. PMID 35502547 DOI: 10.1158/0008-5472.CAN-21-2065  0.357
2021 Ippolito MR, Martis V, Martin S, Tijhuis AE, Hong C, Wardenaar R, Dumont M, Zerbib J, Spierings DCJ, Fachinetti D, Ben-David U, Foijer F, Santaguida S. Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy. Developmental Cell. PMID 34352223 DOI: 10.1016/j.devcel.2021.07.006  0.355
2021 Wang RW, Viganò S, Ben-David U, Amon A, Santaguida S. Aneuploid senescent cells activate NF-κB to promote their immune clearance by NK cells. Embo Reports. e52032. PMID 34105235 DOI: 10.15252/embr.202052032  0.308
2021 Cohen-Sharir Y, McFarland JM, Abdusamad M, Marquis C, Bernhard SV, Kazachkova M, Tang H, Ippolito MR, Laue K, Zerbib J, Malaby HLH, Jones A, Stautmeister LM, Bockaj I, Wardenaar R, ... ... Ben-David U, et al. Aneuploidy renders cancer cells vulnerable to mitotic checkpoint inhibition. Nature. PMID 33505028 DOI: 10.1038/s41586-020-03114-6  0.666
2020 Rendo V, Enache OM, Ben-David U. Adding to the CASeload: unwarranted p53 signaling induced by Cas9. Molecular & Cellular Oncology. 7: 1789419. PMID 32944644 DOI: 10.1080/23723556.2020.1789419  0.311
2020 Corsello SM, Nagari RT, Spangler RD, Rossen J, Kocak M, Bryan JG, Humeidi R, Peck D, Wu X, Tang AA, Wang VM, Bender SA, Lemire E, Narayan R, Montgomery P, ... Ben-David U, et al. Discovering the anti-cancer potential of non-oncology drugs by systematic viability profiling. Nature Cancer. 1: 235-248. PMID 32613204 DOI: 10.1038/s43018-019-0018-6  0.597
2020 Enache OM, Rendo V, Abdusamad M, Lam D, Davison D, Pal S, Currimjee N, Hess J, Pantel S, Nag A, Thorner AR, Doench JG, Vazquez F, Beroukhim R, Golub TR, ... Ben-David U, et al. Author Correction: Cas9 activates the p53 pathway and selects for p53-inactivating mutations. Nature Genetics. PMID 32587373 DOI: 10.1038/S41588-020-0663-9  0.505
2020 Enache OM, Rendo V, Abdusamad M, Lam D, Davison D, Pal S, Currimjee N, Hess J, Pantel S, Nag A, Thorner AR, Doench JG, Vazquez F, Beroukhim R, Golub TR, ... Ben-David U, et al. Cas9 activates the p53 pathway and selects for p53-inactivating mutations. Nature Genetics. PMID 32424350 DOI: 10.1038/S41588-020-0623-4  0.634
2020 Corsello SM, Nagari RT, Spangler RD, Rossen J, Kocak M, Bryan JG, Humeidi R, Peck D, Wu X, Tang AA, Wang VM, Bender SA, Lemire E, Narayan R, Montgomery P, ... Ben-David U, et al. Discovering the anticancer potential of non-oncology drugs by systematic viability profiling Nature Cancer. 1: 235-248. DOI: 10.1038/s43018-019-0018-6  0.41
2019 Ben-David U, Amon A. Context is everything: aneuploidy in cancer. Nature Reviews. Genetics. PMID 31548659 DOI: 10.1038/S41576-019-0171-X  0.407
2018 Ben-David U, Beroukhim R, Golub TR. Genomic evolution of cancer models: perils and opportunities. Nature Reviews. Cancer. PMID 30578414 DOI: 10.1038/S41568-018-0095-3  0.65
2018 Ben-David U, Siranosian B, Ha G, Tang H, Oren Y, Hinohara K, Strathdee CA, Dempster J, Lyons NJ, Burns R, Nag A, Kugener G, Cimini B, Tsvetkov P, Maruvka YE, et al. Genetic and transcriptional evolution alters cancer cell line drug response. Nature. PMID 30089904 DOI: 10.1038/S41586-018-0409-3  0.714
2018 Abdeen SK, Ben-David U, Shweiki A, Maly B, Aqeilan RI. Somatic loss of WWOX is associated with TP53 perturbation in basal-like breast cancer. Cell Death & Disease. 9: 832. PMID 30082886 DOI: 10.1038/s41419-018-0896-z  0.314
2018 Ben-David U, Siranosian B, Ha G, Tang H, Lyons NJ, Burns R, Nag A, Cimini B, Tsvetkov P, Tubelli AA, Wong B, Thorner AR, Bittker J, Meyerson M, Beroukhim R, et al. Abstract 214: Genetic and transcriptional instability alters cell line drug response Cancer Research. 78: 214-214. DOI: 10.1158/1538-7445.Am2018-214  0.674
2018 Ben-David U, Ha G, Tseng Y, Greenwald NF, Oh C, Shih J, McFarland JM, Wong B, Boehm JS, Beroukhim R, Golub TR. Abstract 1028: Patient-derived xenografts undergo mouse-specific tumor evolution Tumor Biology. DOI: 10.1158/1538-7445.Am2018-1028  0.423
2017 Ben-David U, Ha G, Tseng YY, Greenwald NF, Oh C, Shih J, McFarland JM, Wong B, Boehm JS, Beroukhim R, Golub TR. Patient-derived xenografts undergo mouse-specific tumor evolution. Nature Genetics. PMID 28991255 DOI: 10.1038/Ng.3967  0.641
2016 Bi WL, Horowtiz P, Greenwald N, Abedalthagafi M, Agarwalla PK, Gibson WJ, Mei Y, Schumacher SE, Ben-David U, Chevalier A, Carter SL, Tiao G, Brastianos PK, Ligon AH, Ducar M, et al. Landscape of genomic alterations in pituitary adenomas. Clinical Cancer Research : An Official Journal of the American Association For Cancer Research. PMID 27707790 DOI: 10.1158/1078-0432.Ccr-16-0790  0.583
2016 Ben-David U, Ha G, Khadka P, Jin X, Wong B, Franke L, Golub TR. The landscape of chromosomal aberrations in breast cancer mouse models reveals driver-specific routes to tumorigenesis. Nature Communications. 7: 12160. PMID 27374210 DOI: 10.1038/Ncomms12160  0.63
2016 Aguirre AJ, Meyers RM, Weir BA, Vazquez F, Zhang CZ, Ben-David U, Cook A, Ha G, Harrington WF, Doshi MB, Kost-Alimova M, Gill S, Xu H, Ali LD, Jiang G, et al. Genomic copy number dictates a gene-independent cell response to CRISPR-Cas9 targeting. Cancer Discovery. PMID 27260156 DOI: 10.1158/2159-8290.Cd-16-0154  0.613
2016 Ben-David U, Ha G, Khadka P, Jin X, Franke L, Golub TR. The landscape of chromosomal aberrations in mouse models of breast cancer reveals driver-specific routes to tumor development Cancer Research. 76: 2683-2683. DOI: 10.1158/1538-7445.Am2016-2683  0.466
2015 Ben-David U. Genomic instability, driver genes and cell selection: Projections from cancer to stem cells. Biochimica Et Biophysica Acta. 1849: 427-35. PMID 25132386 DOI: 10.1016/j.bbagrm.2014.08.005  0.351
2014 Ben-David U, Arad G, Weissbein U, Mandefro B, Maimon A, Golan-Lev T, Narwani K, Clark AT, Andrews PW, Benvenisty N, Carlos Biancotti J. Aneuploidy induces profound changes in gene expression, proliferation and tumorigenicity of human pluripotent stem cells. Nature Communications. 5: 4825. PMID 25198699 DOI: 10.1038/Ncomms5825  0.318
2014 Ben-David U, Biran A, Scaffidi P, Herold-Mende C, Boehringer M, Meshorer E, Benvenisty N. Elimination of undifferentiated cancer cells by pluripotent stem cell inhibitors. Journal of Molecular Cell Biology. 6: 267-9. PMID 24683201 DOI: 10.1093/Jmcb/Mju012  0.331
2013 Ben-David U, Mayshar Y, Benvenisty N. Virtual karyotyping of pluripotent stem cells on the basis of their global gene expression profiles. Nature Protocols. 8: 989-97. PMID 23619890 DOI: 10.1038/Nprot.2013.051  0.305
2012 Ben-David U, Benvenisty N. High prevalence of evolutionarily conserved and species-specific genomic aberrations in mouse pluripotent stem cells. Stem Cells (Dayton, Ohio). 30: 612-22. PMID 22328490 DOI: 10.1002/Stem.1057  0.317
2010 Mayshar Y, Ben-David U, Lavon N, Biancotti JC, Yakir B, Clark AT, Plath K, Lowry WE, Benvenisty N. Identification and classification of chromosomal aberrations in human induced pluripotent stem cells. Cell Stem Cell. 7: 521-31. PMID 20887957 DOI: 10.1016/J.Stem.2010.07.017  0.333
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