Timothy James Merkel - Publications

Affiliations: 
Northwestern University, Evanston, IL 
Area:
Nanotechnology, Polymer Chemistry, Nanomedicine

18/62 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2017 Sita TL, Kouri FM, Hurley LA, Merkel TJ, Chalastanis A, May JL, Ghelfi ST, Cole LE, Cayton TC, Barnaby SN, Sprangers AJ, Savalia N, James CD, Lee A, Mirkin CA, et al. Dual bioluminescence and near-infrared fluorescence monitoring to evaluate spherical nucleic acid nanoconjugate activity in vivo. Proceedings of the National Academy of Sciences of the United States of America. PMID 28373576 DOI: 10.1073/Pnas.1702736114  0.729
2016 Chinen AB, Ferrer JR, Merkel TJ, Mirkin CA. Relationships between Poly(ethylene glycol) Modifications on RNA-Spherical Nucleic Acid Conjugates and Cellular Uptake and Circulation Time. Bioconjugate Chemistry. PMID 27762539 DOI: 10.1021/Acs.Bioconjchem.6B00483  0.759
2015 Chinen AB, Guan CM, Ferrer JR, Barnaby SN, Merkel TJ, Mirkin CA. Nanoparticle Probes for the Detection of Cancer Biomarkers, Cells, and Tissues by Fluorescence. Chemical Reviews. 115: 10530-74. PMID 26313138 DOI: 10.1021/Acs.Chemrev.5B00321  0.696
2015 Kouri FM, Hurley LA, Daniel WL, Day ES, Hua Y, Hao L, Peng CY, Merkel TJ, Queisser MA, Ritner C, Zhang H, James CD, Sznajder JI, Chin L, Giljohann DA, et al. miR-182 integrates apoptosis, growth, and differentiation programs in glioblastoma. Genes & Development. 29: 732-45. PMID 25838542 DOI: 10.1101/Gad.257394.114  0.738
2015 Radovic-Moreno AF, Chernyak N, Mader CC, Nallagatla S, Kang RS, Hao L, Walker DA, Halo TL, Merkel TJ, Rische CH, Anantatmula S, Burkhart M, Mirkin CA, Gryaznov SM. Immunomodulatory spherical nucleic acids. Proceedings of the National Academy of Sciences of the United States of America. 112: 3892-7. PMID 25775582 DOI: 10.1073/Pnas.1502850112  0.71
2015 Calabrese CM, Merkel TJ, Briley WE, Randeria PS, Narayan SP, Rouge JL, Walker DA, Scott AW, Mirkin CA. Biocompatible infinite-coordination-polymer nanoparticle-nucleic-acid conjugates for antisense gene regulation. Angewandte Chemie (International Ed. in English). 54: 476-80. PMID 25393766 DOI: 10.1002/anie.201407946  0.71
2013 Jensen SA, Day ES, Ko CH, Hurley LA, Luciano JP, Kouri FM, Merkel TJ, Luthi AJ, Patel PC, Cutler JI, Daniel WL, Scott AW, Rotz MW, Meade TJ, Giljohann DA, et al. Spherical nucleic acid nanoparticle conjugates as an RNAi-based therapy for glioblastoma. Science Translational Medicine. 5: 209ra152. PMID 24174328 DOI: 10.1126/Scitranslmed.3006839  0.703
2012 Chen K, Merkel TJ, Pandya A, Napier ME, Luft JC, Daniel W, Sheiko S, DeSimone JM. Low modulus biomimetic microgel particles with high loading of hemoglobin. Biomacromolecules. 13: 2748-59. PMID 22852860 DOI: 10.1021/Bm3007242  0.539
2012 Merkel TJ, Chen K, Jones SW, Pandya AA, Tian S, Napier ME, Zamboni WE, DeDimone JM. The effect of particle size on the biodistribution of low-modulus hydrogel PRINT particles. Journal of Controlled Release : Official Journal of the Controlled Release Society. 162: 37-44. PMID 22705460 DOI: 10.1016/J.Jconrel.2012.06.009  0.387
2012 Kersey FR, Merkel TJ, Perry JL, Napier ME, DeSimone JM. Effect of aspect ratio and deformability on nanoparticle extravasation through nanopores. Langmuir : the Acs Journal of Surfaces and Colloids. 28: 8773-81. PMID 22612428 DOI: 10.1021/La301279V  0.782
2011 Wang Y, Finlay JA, Betts DE, Merkel TJ, Luft JC, Callow ME, Callow JA, DeSimone JM. Amphiphilic co-networks with moisture-induced surface segregation for high-performance nonfouling coatings. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 10365-9. PMID 21827199 DOI: 10.1021/La202427Z  0.449
2011 Merkel TJ, DeSimone JM. Dodging drug-resistant cancer with diamonds. Science Translational Medicine. 3: 73ps8. PMID 21389261 DOI: 10.1126/Scitranslmed.3002137  0.496
2011 Merkel TJ, Jones SW, Herlihy KP, Kersey FR, Shields AR, Napier M, Luft JC, Wu H, Zamboni WC, Wang AZ, Bear JE, DeSimone JM. Using mechanobiological mimicry of red blood cells to extend circulation times of hydrogel microparticles. Proceedings of the National Academy of Sciences of the United States of America. 108: 586-91. PMID 21220299 DOI: 10.1073/Pnas.1010013108  0.753
2011 Wang Y, Merkel TJ, Chen K, Fromen CA, Betts DE, DeSimone JM. Generation of a library of particles having controlled sizes and shapes via the mechanical elongation of master templates. Langmuir : the Acs Journal of Surfaces and Colloids. 27: 524-8. PMID 21166444 DOI: 10.1021/La1045095  0.761
2010 Merkel TJ, Herlihy KP, Nunes J, Orgel RM, Rolland JP, DeSimone JM. Scalable, shape-specific, top-down fabrication methods for the synthesis of engineered colloidal particles. Langmuir : the Acs Journal of Surfaces and Colloids. 26: 13086-96. PMID 20000620 DOI: 10.1021/La903890H  0.761
2010 Herlihy KP, Merkel T, DeSimone JM. Abstract 4342: Multimodal contrast agent development using imprint lithography based techniques: New tools for examining biodistribution Cancer Research. 70: 4342-4342. DOI: 10.1158/1538-7445.Am10-4342  0.725
2010 Barrett DG, Merkel TJ, Luft JC, Yousaf MN. One-step syntheses of photocurable polyesters based on a renewable resource Macromolecules. 43: 9660-9667. DOI: 10.1021/Ma1015424  0.315
2009 Herlihy K, Merkel T, An H, Lin W, Desimone J. Soft lithography-based hydrogel particles and the effect of shape and size on biodistribution Technical Proceedings of the 2009 Nsti Nanotechnology Conference and Expo, Nsti-Nanotech 2009. 2: 60-63.  0.462
Low-probability matches (unlikely to be authored by this person)
2012 Niskala JR, Rice WC, Bruce RC, Merkel TJ, Tsui F, You W. Tunneling characteristics of Au-alkanedithiol-Au junctions formed via nanotransfer printing (nTP). Journal of the American Chemical Society. 134: 12072-82. PMID 22720785 DOI: 10.1021/Ja302602B  0.24
1994 Zhou Y, Merkel TJ, Ebright RH. Characterization of the activating region of Escherichia coli catabolite gene activator protein (CAP) II. Role at class I and class II CAP-dependent promoters Journal of Molecular Biology. 243: 603-610. PMID 7966285 DOI: 10.1016/0022-2836(94)90035-3  0.159
2006 Easley CJ, Karlinsey JM, Bienvenue JM, Legendre LA, Roper MG, Feldman SH, Hughes MA, Hewlett EL, Merkel TJ, Ferrance JP, Landers JP. A fully integrated microfluidic genetic analysis system with sample-in-answer-out capability. Proceedings of the National Academy of Sciences of the United States of America. 103: 19272-7. PMID 17159153 DOI: 10.1073/Pnas.0604663103  0.144
1995 Merkel TJ, Dahl JL, Ebright RH, Kadner RJ. Transcription activation at the Escherichia coli uhpT promoter by the catabolite gene activator protein Journal of Bacteriology. 177: 1712-1718. PMID 7896692 DOI: 10.1128/Jb.177.7.1712-1718.1995  0.137
2009 Loving CL, Khurana T, Osorio M, Lee GM, Kelly VK, Stibitz S, Merkel TJ. Role of anthrax toxins in dissemination, disease progression, and induction of protective adaptive immunity in the mouse aerosol challenge model Infection and Immunity. 77: 255-265. PMID 18955474 DOI: 10.1128/Iai.00633-08  0.126
1992 Merkel TJ, Nelson DM, Brauer CL, Kadner RJ. Promoter elements required for positive control of transcription of the Escherichia coli uhpT gene Journal of Bacteriology. 174: 2763-2770. PMID 1569008  0.121
2012 Hassan F, Ren D, Zhang W, Merkel TJ, Gu XX. Moraxella catarrhalis activates murine macrophages through multiple toll like receptors and has reduced clearance in lungs from TLR4 mutant mice. Plos One. 7: e37610. PMID 22662179 DOI: 10.1371/journal.pone.0037610  0.119
1998 Merkel TJ, Stibitz S, Keith JM, Leef M, Shahin R. Contribution of regulation by the bvg locus to respiratory infection of mice by Bordetella pertussis. Infection and Immunity. 66: 4367-73. PMID 9712789  0.113
2007 Loving CL, Kennett M, Lee GM, Grippe VK, Merkel TJ. Murine aerosol challenge model of anthrax Infection and Immunity. 75: 2689-2698. PMID 17353290 DOI: 10.1128/Iai.01875-06  0.112
2005 Hughes MA, Green CS, Lowchyj L, Lee GM, Grippe VK, Smith MF, Huang LY, Harvill ET, Merkel TJ. MyD88-dependent signaling contributes to protection following Bacillus anthracis spore challenge of mice: Implications for toll-like receptor signaling Infection and Immunity. 73: 7535-7540. PMID 16239556 DOI: 10.1128/Iai.73.11.7535-7540.2005  0.107
2008 Harvill ET, Osorio M, Loving CL, Lee GM, Kelly VK, Merkel TJ. Anamnestic protective immunity to Bacillus anthracis is antibody mediated but independent of complement and Fc receptors Infection and Immunity. 76: 2177-2182. PMID 18316379 DOI: 10.1128/Iai.00647-07  0.106
2009 Loving CL, Osorio M, Kim YG, Nuñez G, Hughes MA, Merkel TJ. Nod1/Nod2-mediated recognition plays a critical role in induction of adaptive immunity to anthrax after aerosol exposure Infection and Immunity. 77: 4529-4537. PMID 19620350 DOI: 10.1128/Iai.00563-09  0.102
2010 Iyer JK, Khurana T, Langer M, West CM, Ballard JD, Metcalf JP, Merkel TJ, Coggeshall KM. Inflammatory cytokine response to Bacillus anthracis peptidoglycan requires phagocytosis and lysosomal trafficking Infection and Immunity. 78: 2418-2428. PMID 20308305 DOI: 10.1128/Iai.00170-10  0.096
2004 Pickering AK, Osorio M, Lee GM, Grippe VK, Bray M, Merkel TJ. Cytokine response to infection with Bacillus anthracis spores Infection and Immunity. 72: 6382-6389. PMID 15501768 DOI: 10.1128/IAI.72.11.6382-6389.2004  0.092
2014 Feinen B, Petrovsky N, Verma A, Merkel TJ. Advax-adjuvanted recombinant protective antigen provides protection against inhalational anthrax that is further enhanced by addition of murabutide adjuvant. Clinical and Vaccine Immunology : Cvi. 21: 580-6. PMID 24554695 DOI: 10.1128/CVI.00019-14  0.091
2009 Osorio M, Wu Y, Singh S, Merkel TJ, Bhattacharyya S, Blake MS, Kopecko DJ. Anthrax protective antigen delivered by salmonella enterica serovar typhi Ty21a protects mice from a lethal anthrax spore challenged Infection and Immunity. 77: 1475-1482. PMID 19179420 DOI: 10.1128/IAI.00828-08  0.087
2012 Banda NK, Hyatt S, Antonioli AH, White JT, Glogowska M, Takahashi K, Merkel TJ, Stahl GL, Mueller-Ortiz S, Wetsel R, Arend WP, Holers VM. Role of C3a receptors, C5a receptors, and complement protein C6 deficiency in collagen antibody-induced arthritis in mice. Journal of Immunology (Baltimore, Md. : 1950). 188: 1469-78. PMID 22205026 DOI: 10.4049/Jimmunol.1102310  0.086
2014 Hewlett EL, Burns DL, Cotter PA, Harvill ET, Merkel TJ, Quinn CP, Stibitz ES. Pertussis pathogenesis--what we know and what we don't know. The Journal of Infectious Diseases. 209: 982-5. PMID 24626533 DOI: 10.1093/Infdis/Jit639  0.079
2013 Brady RA, Mocca CP, Prabhakara R, Plaut RD, Shirtliff ME, Merkel TJ, Burns DL. Evaluation of genetically inactivated alpha toxin for protection in multiple mouse models of Staphylococcus aureus infection. Plos One. 8: e63040. PMID 23658662 DOI: 10.1371/journal.pone.0063040  0.077
2004 Pickering AK, Merkel TJ. Macrophages Release Tumor Necrosis Factor Alpha and Interleukin-12 in Response to Intracellular Bacillus anthracis Spores Infection and Immunity. 72: 3069-3072. PMID 15102824 DOI: 10.1128/IAI.72.5.3069-3072.2004  0.073
2013 Prabhakara R, Foreman O, De Pascalis R, Lee GM, Plaut RD, Kim SY, Stibitz S, Elkins KL, Merkel TJ. Epicutaneous model of community-acquired Staphylococcus aureus skin infections Infection and Immunity. 81: 1306-1315. PMID 23381997 DOI: 10.1128/Iai.01304-12  0.068
2013 Eby JC, Gray MC, Warfel JM, Paddock CD, Jones TF, Day SR, Bowden J, Poulter MD, Donato GM, Merkel TJ, Hewlett EL. Quantification of the adenylate cyclase toxin of Bordetella pertussis in vitro and during respiratory infection. Infection and Immunity. 81: 1390-8. PMID 23429530 DOI: 10.1128/Iai.00110-13  0.066
2013 Merkel TJ, Perera PY, Lee GM, Verma A, Hiroi T, Yokote H, Waldmann TA, Perera LP. Protective-antigen (PA) based anthrax vaccines confer protection against inhalation anthrax by precluding the establishment of a systemic infection Human Vaccines and Immunotherapeutics. 9: 1841-1848. PMID 23787486 DOI: 10.4161/Hv.25337  0.065
2013 Plaut RD, Mocca CP, Prabhakara R, Merkel TJ, Stibitz S. Stably Luminescent Staphylococcus aureus Clinical Strains for Use in Bioluminescent Imaging Plos One. 8. PMID 23555002 DOI: 10.1371/journal.pone.0059232  0.065
2005 Harvill ET, Lee G, Grippe VK, Merkel TJ. Complement depletion renders C57BL/6 mice sensitive to the Bacillus anthracis sterne strain Infection and Immunity. 73: 4420-4422. PMID 15972541 DOI: 10.1128/Iai.73.7.4420-4422.2005  0.06
2008 Tsai P, Cao GL, Merkel TJ, Rosen GM. Spin labelling of Bacillus anthracis endospores: A model for in vivo tracking by EPR imaging Free Radical Research. 42: 49-56. PMID 18324523 DOI: 10.1080/10715760701787701  0.059
1995 Merkel TJ, Stibitz S. Identification of a locus required for the regulation of bvg-repressed genes in Bordetella pertussis Journal of Bacteriology. 177: 2727-2736. PMID 7751282  0.059
2013 Warfel JM, Merkel TJ. Bordetella pertussis infection induces a mucosal IL-17 response and long-lived Th17 and Th1 immune memory cells in nonhuman primates Mucosal Immunology. 6: 787-796. PMID 23187316 DOI: 10.1038/Mi.2012.117  0.058
2012 Plaut RD, Kelly VK, Lee GM, Stibitz S, Merkel TJ. Dissemination bottleneck in a murine model of inhalational anthrax. Infection and Immunity. 80: 3189-93. PMID 22753373 DOI: 10.1128/IAI.00515-12  0.054
2012 Warfel JM, Beren J, Kelly VK, Lee G, Merkel TJ. Nonhuman primate model of pertussis. Infection and Immunity. 80: 1530-6. PMID 22252879 DOI: 10.1128/Iai.06310-11  0.054
2005 Cróinín TO, Grippe VK, Merkel TJ. Activation of the vrg6 promoter of Bordetella pertussis by RisA Journal of Bacteriology. 187: 1648-1658. PMID 15716435 DOI: 10.1128/JB.187.5.1648-1658.2005  0.05
1998 Merkel TJ, Barros C, Stibitz S. Characterization of the bvgR locus of Bordetella pertussis Journal of Bacteriology. 180: 1682-1690. PMID 9537363  0.05
2010 Merkel TJ, Perera PY, Kelly VK, Verma A, Llewellyn ZN, Waldmann TA, Mosca JD, Perera LP. Development of a highly efficacious vaccinia-based dual vaccine against smallpox and anthrax, two important bioterror entities. Proceedings of the National Academy of Sciences of the United States of America. 107: 18091-6. PMID 20921397 DOI: 10.1073/Pnas.1013083107  0.045
2003 Merkel TJ, Boucher PE, Stibitz S, Grippe VK. Analysis of bvgR Expression in Bordetella pertussis Journal of Bacteriology. 185: 6902-6912. PMID 14617654 DOI: 10.1128/JB.185.23.6902-6912.2003  0.045
2014 Warfel JM, Merkel TJ. The baboon model of pertussis: Effective use and lessons for pertussis vaccines Expert Review of Vaccines. 13: 1241-1252. PMID 25182980 DOI: 10.1586/14760584.2014.946016  0.044
2012 Warfel JM, Beren J, Merkel TJ. Airborne transmission of bordetella pertussis Journal of Infectious Diseases. 206: 902-906. PMID 22807521 DOI: 10.1093/Infdis/Jis443  0.042
2015 Warfel JM, Zimmerman LI, Merkel TJ. Comparison of Three Whole-cell Pertussis Vaccines in the Baboon Model of Pertussis. Clinical and Vaccine Immunology : Cvi. PMID 26561389 DOI: 10.1128/Cvi.00449-15  0.038
2014 Warfel JM, Zimmerman LI, Merkel TJ. Acellular pertussis vaccines protect against disease butfail to prevent infection and transmission ina nonhuman primate model Proceedings of the National Academy of Sciences of the United States of America. 111: 787-792. PMID 24277828 DOI: 10.1073/Pnas.1314688110  0.033
2015 Boinett CJ, Harris SR, Langridge GC, Trainor EA, Merkel TJ, Parkhill J. Complete Genome Sequence of Bordetella pertussis D420. Genome Announcements. 3. PMID 26067980 DOI: 10.1128/genomeA.00657-15  0.031
2014 Merkel TJ, Halperin SA. Nonhuman primate and human challenge models of pertussis Journal of Infectious Diseases. 209: S20-S23. PMID 24626867 DOI: 10.1093/infdis/jit493  0.028
2014 Warfel JM, Merkel TJ. Reply to Domenech de Cellès et al.: Infection and transmission of pertussis in the baboon model Proceedings of the National Academy of Sciences of the United States of America. 111: E718. PMID 24693544 DOI: 10.1073/Pnas.1324074111  0.019
2014 Warfel JM, Papin JF, Wolf RF, Zimmerman LI, Merkel TJ. Maternal and neonatal vaccination protects newborn baboons from pertussis infection Journal of Infectious Diseases. 210: 604-610. PMID 24526741 DOI: 10.1093/Infdis/Jiu090  0.015
2015 Trainor EA, Nicholson TL, Merkel TJ. Bordetella pertussis transmission. Pathogens and Disease. 73: ftv068. PMID 26374235 DOI: 10.1093/femspd/ftv068  0.01
2015 Boinett CJ, Harris SR, Langridge GC, Trainor EA, Merkel TJ, Parkhill J. Erratum for Boinett et al., Complete Genome Sequence of Bordetella pertussis D420. Genome Announcements. 3. PMID 26184951 DOI: 10.1128/genomeA.00842-15  0.01
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