Stefan H Oehlers - Publications

Affiliations: 
A*STAR Infectious Diseases Labs 
Area:
Tuberculosis, infection and immunity, zebrafish

53 high-probability publications. We are testing a new system for linking publications to authors. You can help! If you notice any inaccuracies, please sign in and mark papers as correct or incorrect matches. If you identify any major omissions or other inaccuracies in the publication list, please let us know.

Year Citation  Score
2024 Wright K, Han DJ, Song R, de Silva K, Plain KM, Purdie AC, Shepherd A, Chin M, Hortle E, Wong JJ, Britton WJ, Oehlers SH. Zebrafish and increase susceptibility to mycobacterial infection. Life Science Alliance. 7. PMID 38307625 DOI: 10.26508/lsa.202302523  0.38
2023 Johansen MD, Spaink HP, Oehlers SH, Kremer L. Modeling nontuberculous mycobacterial infections in zebrafish. Trends in Microbiology. PMID 38135617 DOI: 10.1016/j.tim.2023.11.011  0.751
2023 Resseguier J, Nguyen-Chi M, Wohlmann J, Rigaudeau D, Salinas I, Oehlers SH, Wiegertjes GF, Johansen FE, Qiao SW, Koppang EO, Verrier B, Boudinot P, Griffiths G. Identification of a pharyngeal mucosal lymphoid organ in zebrafish and other teleosts: Tonsils in fish? Science Advances. 9: eadj0101. PMID 37910624 DOI: 10.1126/sciadv.adj0101  0.656
2023 Shihana F, Cholan PM, Fraser S, Oehlers SH, Seth D. Investigating the role of lipid genes in liver disease using fatty liver models of alcohol and high fat in zebrafish (Danio rerio). Liver International : Official Journal of the International Association For the Study of the Liver. PMID 37650211 DOI: 10.1111/liv.15716  0.598
2023 Dupuy A, Aponte Santamaría C, Yeheskel A, Hortle E, Oehlers SH, Gräter F, Hogg PJ, Passam FH, Chiu J. Mechano-Redox Control of Macrophage-1 Antigen De-Adhesion From ICAM-1 (Intercellular Adhesion Molecule 1) by Protein Disulfide Isomerase Promotes Directional Movement Under Flow. Circulation Research. PMID 37021588 DOI: 10.1161/CIRCRESAHA.122.321926  0.64
2022 Kam JY, Wright K, Britton WJ, Oehlers SH. Treatment of infection-induced vascular pathologies is protective against persistent rough morphotype Mycobacterium abscessus infection in zebrafish. Microbial Pathogenesis. 167: 105590. PMID 35588967 DOI: 10.1016/j.micpath.2022.105590  0.731
2022 Hortle E, Tran VL, Wright K, Fontaine AR, Pinello N, O'Rourke MB, Wong JJ, Hansbro PM, Britton WJ, Oehlers SH. OXSR1 inhibits inflammasome activation by limiting potassium efflux during mycobacterial infection. Life Science Alliance. 5. PMID 35545295 DOI: 10.26508/lsa.202201476  0.734
2022 Kam JY, Cheng T, Garland DC, Britton WJ, Tobin DM, Oehlers SH. Inhibition of infection-induced vascular permeability modulates host leukocyte recruitment to Mycobacterium marinum granulomas in zebrafish. Pathogens and Disease. 80. PMID 35438161 DOI: 10.1093/femspd/ftac009  0.8
2022 Hawkins PME, Hoi DM, Cheung CY, Wang T, Quan D, Sasi VM, Liu DY, Linington RG, Jackson CJ, Oehlers SH, Cook GM, Britton WJ, Clausen T, Payne RJ. Potent Bactericidal Antimycobacterials Targeting the Chaperone ClpC1 Based on the Depsipeptide Natural Products Ecumicin and Ohmyungsamycin A. Journal of Medicinal Chemistry. PMID 35293761 DOI: 10.1021/acs.jmedchem.1c02122  0.656
2022 Kam JY, Hortle E, Krogman E, Warner SE, Wright K, Luo K, Cheng T, Manuneedhi Cholan P, Kikuchi K, Triccas JA, Britton WJ, Johansen MD, Kremer L, Oehlers SH. Rough and smooth variants of Mycobacterium abscessus are differentially controlled by host immunity during chronic infection of adult zebrafish. Nature Communications. 13: 952. PMID 35177649 DOI: 10.1038/s41467-022-28638-5  0.74
2022 Luo K, Ogawa M, Ayer A, Britton WJ, Stocker R, Kikuchi K, Oehlers SH. Zebrafish Is Necessary for Normal Development and Macrophage Migration. Zebrafish. 19: 7-17. PMID 35108124 DOI: 10.1089/zeb.2021.0058  0.644
2021 Morris S, Wright K, Malyla V, Britton WJ, Hansbro PM, Manuneedhi Cholan P, Oehlers SH. Exposure to the gut microbiota from cigarette smoke-exposed mice exacerbates cigarette smoke extract-induced inflammation in zebrafish larvae. Current Research in Immunology. 2: 229-236. PMID 35492390 DOI: 10.1016/j.crimmu.2021.12.001  0.634
2021 Ding L, Luo K, Feng CG, Oehlers SH. Pidotimod increases inflammation in wounded zebrafish embryos. Fish & Shellfish Immunology. PMID 34922016 DOI: 10.1016/j.fsi.2021.12.013  0.735
2021 Tran W, Kusay AS, Hawkins PME, Cheung CY, Nagalingam G, Pujari V, Ford DJ, Stoye A, Ochoa JL, Audette RE, Hortle E, Oehlers SH, Charman SA, Linington RG, Rubin EJ, et al. Synthetic Sansanmycin Analogues as Potent Translocase I Inhibitors. Journal of Medicinal Chemistry. 64: 17326-17345. PMID 34845906 DOI: 10.1021/acs.jmedchem.1c01407  0.647
2021 Tran VLT, Hortle E, Britton WJ, Oehlers SH. Common anti-haemostatic medications increase the severity of systemic infection by uropathogenic Escherichia coli. Microbiological Research. 254: 126918. PMID 34798538 DOI: 10.1016/j.micres.2021.126918  0.721
2021 Manuneedhi Cholan P, Morris S, Luo K, Chen J, Boland JA, McCaughan GW, Britton WJ, Oehlers SH. Transplantation of high fat fed mouse microbiota into zebrafish larvae identifies MyD88-dependent acceleration of hyperlipidaemia by Gram-positive cell wall components. Biofactors (Oxford, England). 48: 329-341. PMID 34665899 DOI: 10.1002/biof.1796  0.663
2021 Hoque MM, Noorian P, Espinoza-Vergara G, Manuneedhi Cholan P, Kim M, Rahman MH, Labbate M, Rice SA, Pernice M, Oehlers SH, McDougald D. Adaptation to an amoeba host drives selection of virulence-associated traits in Vibrio cholerae. The Isme Journal. PMID 34654895 DOI: 10.1038/s41396-021-01134-2  0.661
2021 Yang H, Wang F, Guo X, Liu F, Liu Z, Wu X, Zhao M, Ma M, Liu H, Qin L, Wang L, Tang T, Sha W, Wang Y, Chen J, ... ... Oehlers SH, et al. Interception of host fatty acid metabolism by mycobacteria under hypoxia to suppress anti-TB immunity. Cell Discovery. 7: 90. PMID 34608123 DOI: 10.1038/s41421-021-00301-1  0.705
2021 Morris S, Cholan PM, Britton WJ, Oehlers SH. Glucose inhibits haemostasis and accelerates diet-induced hyperlipidaemia in zebrafish larvae. Scientific Reports. 11: 19049. PMID 34561530 DOI: 10.1038/s41598-021-98566-9  0.638
2021 Luo K, Stocker R, Britton WJ, Kikuchi K, Oehlers SH. Heme oxygenase limits Mycobacterium marinum infection-induced detrimental ferrostatin-sensitive cell death in zebrafish. The Febs Journal. PMID 34544203 DOI: 10.1111/febs.16209  0.73
2021 Wright K, de Silva K, Plain KM, Purdie AC, Blair TA, Duggin IG, Britton WJ, Oehlers SH. Mycobacterial infection-induced miR-206 inhibits protective neutrophil recruitment via the CXCL12/CXCR4 signalling axis. Plos Pathogens. 17: e1009186. PMID 33826679 DOI: 10.1371/journal.ppat.1009186  0.704
2021 Cronan MR, Hughes EJ, Brewer WJ, Viswanathan G, Hunt EG, Singh B, Mehra S, Oehlers SH, Gregory SG, Kaushal D, Tobin DM. A non-canonical type 2 immune response coordinates tuberculous granuloma formation and epithelialization. Cell. PMID 33761328 DOI: 10.1016/j.cell.2021.02.046  0.809
2020 Cholan PM, Han A, Woodie BR, Watchon M, Kurz AR, Laird AS, Britton WJ, Ye L, Holmes ZC, McCann JR, David LA, Rawls JF, Oehlers SH. Conserved anti-inflammatory effects and sensing of butyrate in zebrafish. Gut Microbes. 12: 1-11. PMID 33064972 DOI: 10.1080/19490976.2020.1824563  0.681
2020 Oehlers SH, Hortle E, Cook KM. A zebrafish model of tuberculosis comorbidity and the effects of HIF-activating intervention. The Febs Journal. PMID 32652856 DOI: 10.1111/febs.15463  0.711
2020 Hortle E, Oehlers SH. Host-directed therapies targeting the tuberculosis granuloma stroma. Pathogens and Disease. 78. PMID 32149337 DOI: 10.1093/femspd/ftaa015  0.743
2019 Cheng T, Kam JY, Johansen MD, Oehlers SH. High content analysis of granuloma histology and neutrophilic inflammation in adult zebrafish infected with Mycobacterium marinum. Micron (Oxford, England : 1993). 129: 102782. PMID 31775097 DOI: 10.1016/j.micron.2019.102782  0.751
2019 Obeidy P, Ju LA, Oehlers SH, Zulkhernain NS, Lee Q, Galeano JL, Niño, Kwan R, Tikoo S, Cavanagh LL, Mrass P, Cook A, Jackson SP, Biro M, Roediger B, et al. Partial loss of actin nucleator Actin Related Protein 2/3 activity triggers blebbing in primary T lymphocytes. Immunology and Cell Biology. PMID 31698518 DOI: 10.1111/imcb.12304  0.618
2019 Oehlers SH. Revisiting hypoxia therapies for tuberculosis. Clinical Science (London, England : 1979). 133: 1271-1280. PMID 31209098 DOI: 10.1042/CS20190415  0.695
2019 Black HD, Xu W, Hortle E, Roberston SI, Britton WJ, Kaur A, New EJ, Witting PK, Chami B, Oehlers SH. The cyclic nitroxide antioxidant 4-methoxy-TEMPO decreases mycobacterial burden in vivo through host and bacterial targets. Free Radical Biology & Medicine. PMID 30878645 DOI: 10.1016/J.Freeradbiomed.2019.03.010  0.737
2019 Hortle E, Johnson KE, Johansen MD, Nguyen T, Shavit JA, Britton WJ, Tobin DM, Oehlers SH. Thrombocyte inhibition restores protective immunity to mycobacterial infection in zebrafish. The Journal of Infectious Diseases. PMID 30877311 DOI: 10.1093/Infdis/Jiz110  0.817
2018 Johansen MD, Hortle E, Kasparian JA, Romero A, Novoa B, Figueras A, Britton WJ, de Silva K, Purdie AC, Oehlers SH. Analysis of mycobacterial infection-induced changes to host lipid metabolism in a zebrafish infection model reveals a conserved role for LDLR in infection susceptibility. Fish & Shellfish Immunology. PMID 30219383 DOI: 10.1016/j.fsi.2018.09.037  0.726
2018 Johansen MD, Kasparian JA, Hortle E, Britton WJ, Purdie AC, Oehlers SH. Mycobacterium marinum infection drives foam cell differentiation in zebrafish infection models. Developmental and Comparative Immunology. PMID 30040967 DOI: 10.1016/j.dci.2018.07.022  0.746
2018 Spain M, Wong JK, Nagalingam G, Batten JM, Hortle E, Oehlers S, Jiang XF, Murage HE, Orford JT, Crisologo P, Triccas JA, Rutledge PJ, Todd MH. Anti-Tubercular bis-Substituted Cyclam Derivatives: Structure-Activity Relationships and In Vivo Studies. Journal of Medicinal Chemistry. PMID 29558124 DOI: 10.1021/Acs.Jmedchem.7B01569  0.629
2017 Alvarez MI, Glover LC, Luo P, Wang L, Theusch E, Oehlers SH, Walton EM, Tram TTB, Kuang YL, Rotter JI, McClean CM, Chinh NT, Medina MW, Tobin DM, Dunstan SJ, et al. Human genetic variation in VAC14 regulates Salmonella invasion and typhoid fever through modulation of cholesterol. Proceedings of the National Academy of Sciences of the United States of America. PMID 28827342 DOI: 10.1073/Pnas.1706070114  0.778
2016 Oehlers SH, Flores MV, Hall CJ, Wang L, Ko DC, Crosier KE, Crosier PS. A whole animal chemical screen approach to identify modifiers of intestinal neutrophilic inflammation. The Febs Journal. PMID 27885812 DOI: 10.1111/Febs.13976  0.65
2016 Cronan MR, Beerman RW, Rosenberg AF, Saelens JW, Johnson MG, Oehlers SH, Sisk DM, Jurcic Smith KL, Medvitz NA, Miller SE, Trinh LA, Fraser SE, Madden JF, Turner J, Stout JE, et al. Macrophage Epithelial Reprogramming Underlies Mycobacterial Granuloma Formation and Promotes Infection. Immunity. 45: 861-876. PMID 27760340 DOI: 10.1016/J.Immuni.2016.09.014  0.796
2016 Oehlers SH, Cronan MR, Beerman RW, Johnson MG, Huang J, Kontos CD, Stout JE, Tobin DM. Infection-induced vascular permeability aids mycobacterial growth. The Journal of Infectious Diseases. PMID 27496976 DOI: 10.1093/Infdis/Jiw355  0.798
2016 Matty MA, Oehlers SH, Tobin DM. Live Imaging of Host-Pathogen Interactions in Zebrafish Larvae. Methods in Molecular Biology (Clifton, N.J.). 1451: 207-23. PMID 27464810 DOI: 10.1007/978-1-4939-3771-4_14  0.777
2015 Cronan MR, Rosenberg AF, Oehlers SH, Saelens JW, Sisk DM, Smith KL, Lee S, Tobin DM. CLARITY and PACT-based imaging of adult zebrafish and mouse for whole-animal analysis of infections. Disease Models & Mechanisms. PMID 26449262 DOI: 10.1242/Dmm.021394  0.793
2015 Tenor JL, Oehlers SH, Yang JL, Tobin DM, Perfect JR. Live Imaging of Host-Parasite Interactions in a Zebrafish Infection Model Reveals Cryptococcal Determinants of Virulence and Central Nervous System Invasion. Mbio. 6. PMID 26419880 DOI: 10.1128/Mbio.01425-15  0.818
2015 Wang L, Oehlers SH, Espenschied ST, Rawls JF, Tobin DM, Ko DC. CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation. Genome Biology. 16: 190. PMID 26374098 DOI: 10.1186/S13059-015-0722-1  0.734
2015 Okuda KS, Misa JP, Oehlers SH, Hall CJ, Ellett F, Alasmari S, Lieschke GJ, Crosier KE, Crosier PS, Astin JW. A zebrafish model of inflammatory lymphangiogenesis. Biology Open. 4: 1270-80. PMID 26369931 DOI: 10.1242/bio.013540  0.638
2015 Chew TS, O'Shea NR, Sewell GW, Oehlers SH, Mulvey CM, Crosier PS, Godovac-Zimmermann J, Bloom SL, Smith AM, Segal AW. Optineurin deficiency in mice contributes to impaired cytokine secretion and neutrophil recruitment in bacteria-driven colitis. Disease Models & Mechanisms. 8: 817-29. PMID 26044960 DOI: 10.1242/dmm.020362  0.689
2015 Oehlers SH, Cronan MR, Scott NR, Thomas MI, Okuda KS, Walton EM, Beerman RW, Crosier PS, Tobin DM. Interception of host angiogenic signalling limits mycobacterial growth. Nature. 517: 612-5. PMID 25470057 DOI: 10.1038/Nature13967  0.806
2013 Hall CJ, Boyle RH, Astin JW, Flores MV, Oehlers SH, Sanderson LE, Ellett F, Lieschke GJ, Crosier KE, Crosier PS. Immunoresponsive gene 1 augments bactericidal activity of macrophage-lineage cells by regulating β-oxidation-dependent mitochondrial ROS production. Cell Metabolism. 18: 265-78. PMID 23931757 DOI: 10.1016/j.cmet.2013.06.018  0.713
2013 Oehlers SH, Flores MV, Hall CJ, Okuda KS, Sison JO, Crosier KE, Crosier PS. Chemically induced intestinal damage models in zebrafish larvae. Zebrafish. 10: 184-93. PMID 23448252 DOI: 10.1089/zeb.2012.0824  0.667
2012 Oehlers SH, Flores MV, Hall CJ, Crosier KE, Crosier PS. Retinoic acid suppresses intestinal mucus production and exacerbates experimental enterocolitis. Disease Models & Mechanisms. 5: 457-67. PMID 22563081 DOI: 10.1242/dmm.009365  0.681
2012 Hall CJ, Flores MV, Oehlers SH, Sanderson LE, Lam EY, Crosier KE, Crosier PS. Infection-responsive expansion of the hematopoietic stem and progenitor cell compartment in zebrafish is dependent upon inducible nitric oxide. Cell Stem Cell. 10: 198-209. PMID 22305569 DOI: 10.1016/j.stem.2012.01.007  0.683
2011 Oehlers SH, Flores MV, Hall CJ, Swift S, Crosier KE, Crosier PS. The inflammatory bowel disease (IBD) susceptibility genes NOD1 and NOD2 have conserved anti-bacterial roles in zebrafish. Disease Models & Mechanisms. 4: 832-41. PMID 21729873 DOI: 10.1242/dmm.006122  0.706
2011 Crawford KC, Vega Flores M, Oehlers SH, Hall CJ, Crosier KE, Crosier PS. Zebrafish heat shock protein a4 genes in the intestinal epithelium are up-regulated during inflammation. Genesis (New York, N.Y. : 2000). 49: 905-11. PMID 21557452 DOI: 10.1002/dvg.20767  0.643
2011 Oehlers SH, Flores MV, Okuda KS, Hall CJ, Crosier KE, Crosier PS. A chemical enterocolitis model in zebrafish larvae that is dependent on microbiota and responsive to pharmacological agents. Developmental Dynamics : An Official Publication of the American Association of Anatomists. 240: 288-98. PMID 21181946 DOI: 10.1002/dvdy.22519  0.688
2011 Oehlers SH, Flores MV, Chen T, Hall CJ, Crosier KE, Crosier PS. Topographical distribution of antimicrobial genes in the zebrafish intestine. Developmental and Comparative Immunology. 35: 385-91. PMID 21093479 DOI: 10.1016/j.dci.2010.11.008  0.654
2010 Oehlers SH, Flores MV, Hall CJ, O'Toole R, Swift S, Crosier KE, Crosier PS. Expression of zebrafish cxcl8 (interleukin-8) and its receptors during development and in response to immune stimulation. Developmental and Comparative Immunology. 34: 352-9. PMID 19941893 DOI: 10.1016/j.dci.2009.11.007  0.671
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