| Year |
Citation |
Score |
| 2019 |
Bogen S, Gulea M, Fensterbank L, Malacria M. 5-Endo-Trig Radical Cyclizations of Bromomethyldimethylsilyl Diisopropylpropargylic Ethers. A Highly Diastereoselective Access to Functionalized Cyclopentanes. The Journal of Organic Chemistry. 64: 4920-4925. PMID 11674571 DOI: 10.1021/Jo9904260 |
0.343 |
|
| 2019 |
Bogen S, Fensterbank L, Malacria M. Study of a Radical Cyclizations Cascade Leading to Bicyclo[3.1.1]heptanes. The Journal of Organic Chemistry. 64: 819-825. PMID 11674152 DOI: 10.1021/Jo981622U |
0.328 |
|
| 2016 |
Girijavallabhan V, Arasappan A, Bennett F, Chen K, Dang Q, Huang Y, Kerekes A, Nair L, Pissarnitski D, Verma V, Alvarez C, Chen P, Cole D, Esposite S, Huang Y, ... ... Bogen S, et al. 2'-Modified Guanosine Analogs for the Treatment of HCV. Nucleosides, Nucleotides & Nucleic Acids. 1-18. PMID 27104963 DOI: 10.1080/15257770.2016.1154968 |
0.417 |
|
| 2014 |
Dang Q, Zhang Z, Bai Y, Sun R, Yin J, Chen T, Bogen S, Girijavallabhan V, Olsen DB, Meinke PT. Syntheses of nucleosides with a 1′,2′-β-lactam moiety as potential inhibitors of hepatitis C virus NS5B polymerase Tetrahedron Letters. 55: 5576-5579. DOI: 10.1016/J.Tetlet.2014.08.072 |
0.421 |
|
| 2014 |
Dang Q, Zhang Z, Chen T, Tang B, He X, He S, Song Y, Bogen S, Girijavallabhan V, Olsen DB, Meinke PT. Syntheses of 1′,2′-cyclopentyl nucleosides as potential antiviral agents Tetrahedron Letters. 55: 5092-5095. DOI: 10.1016/J.Tetlet.2014.07.037 |
0.394 |
|
| 2014 |
Dang Q, Zhang Z, He S, Liu Y, Chen T, Bogen S, Girijavallabhan V, Olsen DB, Meinke PT. Syntheses of 4′-spirocyclic phosphono-nucleosides as potential inhibitors of hepatitis C virus NS5B polymerase Tetrahedron Letters. 55: 4407-4409. DOI: 10.1016/J.Tetlet.2014.06.029 |
0.473 |
|
| 2014 |
Dang Q, Zhang Z, Tang B, Song Y, Wu L, Chen T, Bogen S, Girijavallabhan V, Olsen DB, Meinke PT. Syntheses of nucleosides with 2′-spirolactam and 2′- spiropyrrolidine moieties as potential inhibitors of hepatitis C virus NS5B polymerase Tetrahedron Letters. 55: 3813-3816. DOI: 10.1016/J.Tetlet.2014.05.051 |
0.442 |
|
| 2012 |
Wang Y, Lipari P, Mirza A, Lin Y, Zhang R, Bogen S, Ma Y, Hicklin DJ, Seidel-Dugan C, Liu S, Wang X, Doll R, Shipps G, Bishop WR. Abstract 2785: Discovery of a novel HDM2 inhibitor with potent in vivo anti-tumor activity Cancer Research. 72: 2785-2785. DOI: 10.1158/1538-7445.Am2012-2785 |
0.312 |
|
| 2010 |
Velázquez F, Sannigrahi M, Bennett F, Lovey RG, Arasappan A, Bogen S, Nair L, Venkatraman S, Blackman M, Hendrata S, Huang Y, Huelgas R, Pinto P, Cheng KC, Tong X, et al. Cyclic sulfones as novel P3-caps for hepatitis C virus NS3/4A (HCV NS3/4A) protease inhibitors: synthesis and evaluation of inhibitors with improved potency and pharmacokinetic profiles. Journal of Medicinal Chemistry. 53: 3075-85. PMID 20302300 DOI: 10.1021/Jm9016027 |
0.444 |
|
| 2010 |
Nair LG, Bogen S, Ruan S, Pan W, Pike R, Tong X, Cheng KC, Guo Z, Doll RJ, Njoroge FG. Towards the second generation of Boceprevir: Dithianes as an alternative P2 substituent for 2,2-dimethyl cycloproyl proline in HCV NS3 protease inhibitors. Bioorganic & Medicinal Chemistry Letters. 20: 1689-92. PMID 20149655 DOI: 10.1016/J.Bmcl.2010.01.037 |
0.461 |
|
| 2010 |
Nair LG, Sannigrahi M, Bogen S, Pinto P, Chen KX, Prongay A, Tong X, Cheng KC, Girijavallabhan V, George Njoroge F. P4 capped amides and lactams as HCV NS3 protease inhibitors with improved potency and DMPK profile. Bioorganic & Medicinal Chemistry Letters. 20: 567-70. PMID 20004570 DOI: 10.1016/J.Bmcl.2009.11.094 |
0.426 |
|
| 2010 |
Liu S, Mirza A, Wang X, Lipari P, Lin Y, Bogen S, Ma Y, Doll R, Shipps G, Seidel-Dugan C, Hicklin DJ, Bishop WR, Wang Y. Abstract 4534: A novel and potent small molecule antagonist of HDM2, SCH 1450206, activates the p53 pathway with mechanism-based activity Cancer Research. 70: 4534-4534. DOI: 10.1158/1538-7445.Am10-4534 |
0.307 |
|
| 2010 |
Wang Y, Wang X, Lipari P, Ponery A, Liu S, Mirza A, Liu Y, Bogen S, Ma Y, Doll R, Shipps G, Liu M, Seidel-Dugan C, Hicklin DJ, Bishop WR. Abstract 4533: In vivo activation of the p53 pathway leading to tumor regression by a novel and potent HDM2 antagonist SCH 1450206 Cancer Research. 70: 4533-4533. DOI: 10.1158/1538-7445.Am10-4533 |
0.304 |
|
| 2010 |
Nair LG, Bogen S, Bennett F, Chen K, Vibulbhan B, Huang Y, Yang W, Doll RJ, Shih N-, Njoroge FG. Design and synthesis of novel fluoro amino acids: synthons for potent macrocyclic HCV NS3 protease inhibitors Tetrahedron Letters. 51: 3057-3061. DOI: 10.1016/J.Tetlet.2010.04.010 |
0.437 |
|
| 2010 |
Nair LG, Bogen S, Doll RJ, Shih N-, Njoroge FG. Synthesis of sterically hindered 3,5,5-trimethyl 2,6-dioxo tetrahydro pyrimidine as HCV protease inhibitors Tetrahedron Letters. 51: 1276-1279. DOI: 10.1016/J.Tetlet.2009.12.129 |
0.467 |
|
| 2009 |
Venkatraman S, Blackman M, Wu W, Nair L, Arasappan A, Padilla A, Bogen S, Bennett F, Chen K, Pichardo J, Tong X, Prongay A, Cheng KC, Girijavallabhan V, George Njoroge F. Discovery of novel P3 sulfonamide-capped inhibitors of HCV NS3 protease. Inhibitors with improved cellular potencies. Bioorganic & Medicinal Chemistry. 17: 4486-95. PMID 19481946 DOI: 10.1016/J.Bmc.2009.05.012 |
0.435 |
|
| 2009 |
Velázquez F, Venkatraman S, Blackman M, Pinto P, Bogen S, Sannigrahi M, Chen K, Pichardo J, Hart A, Tong X, Girijavallabhan V, Njoroge FG. Design, synthesis, and evaluation of oxygen-containing macrocyclic peptidomimetics as inhibitors of HCV NS3 protease. Journal of Medicinal Chemistry. 52: 700-8. PMID 19154150 DOI: 10.1021/Jm801201U |
0.451 |
|
| 2009 |
Venkatraman S, Velazquez F, Wu W, Blackman M, Chen KX, Bogen S, Nair L, Tong X, Chase R, Hart A, Agrawal S, Pichardo J, Prongay A, Cheng KC, Girijavallabhan V, et al. Discovery and structure-activity relationship of P1-P3 ketoamide derived macrocyclic inhibitors of hepatitis C virus NS3 protease. Journal of Medicinal Chemistry. 52: 336-46. PMID 19102654 DOI: 10.1021/Jm800940U |
0.437 |
|
| 2008 |
Bogen S, Arasappan A, Pan W, Ruan S, Padilla A, Saksena AK, Girijavallabhan V, Njoroge FG. Hepatitis C virus NS3-4A serine protease inhibitors: SAR of new P1 derivatives of SCH 503034. Bioorganic & Medicinal Chemistry Letters. 18: 4219-23. PMID 18547808 DOI: 10.1016/J.Bmcl.2008.05.060 |
0.445 |
|
| 2008 |
Tong X, Bogen S, Chase R, Girijavallabhan V, Guo Z, Njoroge FG, Prongay A, Saksena A, Skelton A, Xia E, Ralston R. Characterization of resistance mutations against HCV ketoamide protease inhibitors. Antiviral Research. 77: 177-85. PMID 18201776 DOI: 10.1016/J.Antiviral.2007.11.010 |
0.309 |
|
| 2008 |
Li C, Nair L, Liu T, Li F, Pichardo J, Agrawal S, Chase R, Tong X, Uss AS, Bogen S, Njoroge FG, Morrison RA, Cheng KC. Correlation between PAMPA permeability and cellular activities of hepatitis C virus protease inhibitors. Biochemical Pharmacology. 75: 1186-97. PMID 18164692 DOI: 10.1016/J.Bcp.2007.10.031 |
0.362 |
|
| 2008 |
Bogen S, Goddard J, Fensterbank L, Malacria M. Effect of propargylic substitution on the 5-endo-trig cyclization of bromomethyldimethylsilyl propargyl ethers Arkivoc. 2008. DOI: 10.3998/Ark.5550190.0009.812 |
0.392 |
|
| 2006 |
Guo Z, Prongay A, Tong X, Fischmann T, Bogen S, Velazquez F, Venkatraman S, Njoroge FG, Madison V. Computational Study of the Effects of Mutations A156T, D168V, and D168Q on the Binding of HCV Protease Inhibitors. Journal of Chemical Theory and Computation. 2: 1657-63. PMID 26627036 DOI: 10.1021/Ct600151Y |
0.337 |
|
| 2006 |
Liu R, Abid K, Pichardo J, Pazienza V, Ingravallo P, Kong R, Agrawal S, Bogen S, Saksena A, Cheng K, Prongay A, Njoroge FG, Baroudy BM, Negro F. In vitro antiviral activity of SCH446211 (SCH6), a novel inhibitor of the hepatitis C virus NS3 serine protease Journal of Antimicrobial Chemotherapy. 59: 51-58. PMID 17151003 DOI: 10.1093/Jac/Dkl455 |
0.426 |
|
| 2005 |
Bogen S, Saksena AK, Arasappan A, Gu H, Njoroge FG, Girijavallabhan V, Pichardo J, Butkiewicz N, Prongay A, Madison V. Hepatitis C Virus NS3-4A serine protease inhibitors: Use of a P2-P1 cyclopropyl alanine combination for improved potency. Bioorganic & Medicinal Chemistry Letters. 15: 4515-4519. PMID 16112862 DOI: 10.1016/J.Bmcl.2005.07.009 |
0.438 |
|
| 2003 |
Jao E, Bogen S, Saksena AK, Girijavallabhan V. Preparation of (2,2-dimethylhexahydrofuro[2,3-c]pyrrol-6-yl)methanol: A conformationally restricted congener of nonproteinogenic 3-hydroxy-4-methylproline Synthesis. 2003: 2643-2646. DOI: 10.1055/S-2003-42426 |
0.355 |
|
| 2003 |
Jao E, Bogen S, Saksena AK, Girijavallabhan V. [3+2] Cycloaddition of trimethylenemethane (TMM) to α,β-unsaturated γ-lactam. Preparation of 5,5-fused proline surrogates Tetrahedron Letters. 44: 5033-5035. DOI: 10.1016/S0040-4039(03)01191-2 |
0.337 |
|
| 2001 |
Bogen S, Fensterbank L, Malacria M. Radical cyclization of homopropargylic bromomethyldimethylsilyl ethers. Evidence for a hetero-trans-cycloheptene intermediate Comptes Rendus De L'AcadéMie Des Sciences - Series Iic - Chemistry. 4: 423-426. DOI: 10.1016/S1387-1609(01)01247-6 |
0.359 |
|
| 1997 |
Bogen S, Fensterbank L, Malacria M. Unprecedented Radical Cyclizations Cascade Leading to Bicyclo[3.1.1]Heptanes. Toward a New Generation of Radical Cascades Journal of the American Chemical Society. 119: 5037-5038. DOI: 10.1021/Ja9702879 |
0.311 |
|
| 1996 |
Bogen S, Malacria M. 5-endo-trigRadical Cyclizations: A New Means to the Stereoselective Synthesis of Cyclopentanes and Diquinanes Journal of the American Chemical Society. 118: 3992-3993. DOI: 10.1021/Ja953806L |
0.322 |
|
| 1996 |
Fensterbank L, Dhimane A, Wu S, Lacôte E, Bogen S, Malacria M. Variations on radical cascades of vinyl radicals generated from bromomethyldimethylsilyl propargyl ethers Tetrahedron. 52: 11405-11420. DOI: 10.1016/0040-4020(96)00634-5 |
0.331 |
|
| 1994 |
Bogen S, Journet M, Malacria M. Radical Cyclization of Bromomethyldimethylsilyl Propargyl Ethers; a General Method for the Stereoselective Synthesis of Variously Substituted Trimethylenemethane (TMM) Precursors Synthetic Communications. 24: 1215-1221. DOI: 10.1080/00397919408011720 |
0.387 |
|
| 1994 |
Bogen S, Journet M, Malacria M. Radical Cyclization of Bromomethyldimethylsilyl Propargyl Ethers. Diastereoselective Synthesis of Functionalized Cyclopentanone Precursorsviaa (1,5) Hydrogen-Atom Transfer. Synlett. 1994: 958-960. DOI: 10.1055/S-1994-23063 |
0.301 |
|
| Show low-probability matches. |