Year |
Citation |
Score |
2011 |
Pfefferkorn JA, Guzman-Perez A, Oates PJ, Litchfield J, Aspnes G, Basak A, Benbow J, Berliner MA, Bian J, Choi C, Freeman-Cook K, Corbett JW, Didiuk M, Dunetz JR, Filipski KJ, et al. Designing glucokinase activators with reduced hypoglycemia risk: Discovery of N,N-dimethyl-5-(2-methyl-6-((5-methylpyrazin-2-yl)-carbamoyl)benzofuran-4- yloxy)pyrimidine-2-carboxamide as a clinical candidate for the treatment of type 2 diabetes mellitus Medchemcomm. 2: 828-839. DOI: 10.1039/C1Md00116G |
0.56 |
|
2010 |
Kalgutkar AS, Griffith DA, Ryder T, Sun H, Miao Z, Bauman JN, Didiuk MT, Frederick KS, Zhao SX, Prakash C, Soglia JR, Bagley SW, Bechle BM, Kelley RM, Dirico K, ... ... Benbow JW, et al. Discovery tactics to mitigate toxicity risks due to reactive metabolite formation with 2-(2-hydroxyaryl)-5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3h)-one derivatives, potent calcium-sensing receptor antagonists and clinical candidate(s) for the treatment of osteoporosis. Chemical Research in Toxicology. 23: 1115-26. PMID 20507089 DOI: 10.1021/Tx100137N |
0.52 |
|
2009 |
Didiuk MT, Griffith DA, Benbow JW, Liu KK, Walker DP, Bi FC, Morris J, Guzman-Perez A, Gao H, Bechle BM, Kelley RM, Yang X, Dirico K, Ahmed S, Hungerford W, et al. Short-acting 5-(trifluoromethyl)pyrido[4,3-d]pyrimidin-4(3H)-one derivatives as orally-active calcium-sensing receptor antagonists. Bioorganic & Medicinal Chemistry Letters. 19: 4555-9. PMID 19625189 DOI: 10.1016/J.Bmcl.2009.07.004 |
0.504 |
|
2001 |
Williams DR, Benbow JW, Sattleberg TR, Ihle DC. Zirconium cation coordination in the borohydride-mediated synthesis of β-hydroxy-N-alkoxylamines Tetrahedron Letters. 42: 8597-8601. DOI: 10.1016/S0040-4039(01)01862-7 |
0.498 |
|
1993 |
Benbow JW, McClure KF, Danishefsky SJ. Intramolecular cycloaddition reactions of dienyl nitroso compounds: Application to the synthesis of mitomycin K Journal of the American Chemical Society. 115: 12305-12314. DOI: 10.1021/Ja00079A010 |
0.307 |
|
1991 |
McClure KF, Benbow JW, Danishefsky SJ, Schulte GK. A novel photochemical route to the mitomycin and FR-900482 series Journal of the American Chemical Society. 113: 8185-8186. DOI: 10.1021/Ja00021A064 |
0.454 |
|
1990 |
Williams DR, Benbow JW. Alkylation studies of anions from pyruvate oxime ethers and related derivatives Tetrahedron Letters. 31: 5881-5884. DOI: 10.1016/S0040-4039(00)97984-X |
0.4 |
|
1990 |
Williams DR, Benbow JW, Allen EE. Intramolecular dipolar addition of carbonyl ylides. Studies of substituted bicycloundecanones. Tetrahedron Letters. 31: 6769-6772. DOI: 10.1016/S0040-4039(00)97167-3 |
0.394 |
|
1989 |
Williams DR, Brown DL, Benbow JW. Studies of Stemona alkaloids. Total synthesis of (+)-croomine Journal of the American Chemical Society. 111: 1923-1925. DOI: 10.1021/Ja00187A081 |
0.335 |
|
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