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Nathalie Saurat, Ph.D B.Sc

Affiliations: 
2010-2014 Gurdon Institute University of Cambridge, Cambridge, England, United Kingdom 
 2015- Memorial Sloan-Kettering Cancer Center, Rockville Centre, NY, United States 
Area:
Stem Cells, Neuroscience, Neurodegeneration, Aging, Disease Modelling
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"Nathalie Saurat"
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Publications

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Saurat N, Minotti AP, Rahman MT, et al. (2024) Genome-wide CRISPR screen identifies neddylation as a regulator of neuronal aging and AD neurodegeneration. Cell Stem Cell
Kim TW, Koo SY, Riessland M, et al. (2024) TNF-NF-κB-p53 axis restricts in vivo survival of hPSC-derived dopamine neurons. Cell
Nazeen S, Wang X, Zielinski D, et al. (2024) Deep sequencing of proteotoxicity modifier genes uncovers a Presenilin-2/beta-amyloid-actin genetic risk module shared among alpha-synucleinopathies. Biorxiv : the Preprint Server For Biology
Zhang C, Saurat N, Cornacchia D, et al. (2023) Establishing RNAge to score cellular aging and rejuvenation paradigms and identify novel age-modulating compounds. Biorxiv : the Preprint Server For Biology
Kim TW, Koo SY, Riessland M, et al. (2023) TNF-NFkB-p53 axis restricts survival of hPSC-derived dopamine neuron. Biorxiv : the Preprint Server For Biology
Baggiolini A, Callahan SJ, Montal E, et al. (2021) Developmental chromatin programs determine oncogenic competence in melanoma. Science (New York, N.Y.). 373: eabc1048
Guttikonda SR, Sikkema L, Tchieu J, et al. (2021) Fully defined human pluripotent stem cell-derived microglia and tri-culture system model C3 production in Alzheimer's disease. Nature Neuroscience
Kishinevsky S, Wang T, Rodina A, et al. (2018) HSP90-incorporating chaperome networks as biosensor for disease-related pathways in patient-specific midbrain dopamine neurons. Nature Communications. 9: 4345
Zeltner N, Fattahi F, Dubois NC, et al. (2016) Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nature Medicine
Saurat NG, Livesey FJ, Moore S. (2016) Cortical Differentiation of Human Pluripotent Cells for In Vitro Modeling of Alzheimer's Disease. Methods in Molecular Biology (Clifton, N.J.). 1303: 267-78
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