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Myles H. Akabas

Affiliations: 
Albert Einstein College of Medicine, New York, New York, United States 
Area:
NEUROTRANSMITTER-GATED ION CHANNELS, MALARIA PARASITE PHYSIOLOGY AND MECHANISMS OF CHLOROQUINE RESISTANCE
Website:
http://akabaslab.aecom.yu.edu/index.html
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"Myles Akabas"
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Publications

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Sosa Y, Egbo D, Akabas MH. (2019) Impact of field isolate identified non-synonymous single nucleotide polymorphisms on Equilibrative Nucleoside Transporter 1 (PfENT1) inhibitor efficacy. Acs Infectious Diseases
Sosa Y, Deniskin R, Frame IJ, et al. (2019) Parallel Hit Progression Strategy Identifies Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Parasite Proliferation. Acs Infectious Diseases
Nishtala SN, Arora A, Reyes J, et al. (2018) Accessibility of substituted cysteines in TM2 and TM10 transmembrane segments in the equilibrative nucleoside transporter PfENT1. The Journal of Biological Chemistry
Van Voorhis WC, Adams JH, Adelfio R, et al. (2016) Open Source Drug Discovery with the Malaria Box Compound Collection for Neglected Diseases and Beyond. Plos Pathogens. 12: e1005763
Arora A, Deniskin R, Sosa Y, et al. (2016) Substrate and inhibitor specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1 (PbENT1). Molecular Pharmacology
Deniskin R, Frame IJ, Sosa Y, et al. (2016) Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development. International Journal For Parasitology. Drugs and Drug Resistance. 6: 1-11
Deniskin R, Frame IJ, Sosa Y, et al. (2016) Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development International Journal For Parasitology: Drugs and Drug Resistance. 6: 1-11
Akabas MH. (2015) Cysteine Modification: Probing Channel Structure, Function and Conformational Change. Advances in Experimental Medicine and Biology. 869: 25-54
Frame IJ, Deniskin R, Rinderspacher A, et al. (2015) Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites. Acs Chemical Biology. 10: 775-83
Frame IJ, Deniskin R, Arora A, et al. (2015) Purine import into malaria parasites as a target for antimalarial drug development. Annals of the New York Academy of Sciences. 1342: 19-28
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