Myles H. Akabas
Affiliations: | Albert Einstein College of Medicine, New York, New York, United States |
Area:
NEUROTRANSMITTER-GATED ION CHANNELS, MALARIA PARASITE PHYSIOLOGY AND MECHANISMS OF CHLOROQUINE RESISTANCEWebsite:
http://akabaslab.aecom.yu.edu/index.htmlGoogle:
"Myles Akabas"Mean distance: 14.35 (cluster 16) | S | N | B | C | P |
Parents
Sign in to add mentor| Alan Finkelstein | grad student | Albert Einstein | |
| Arthur Karlin | grad student | Albert Einstein |
Children
Sign in to add trainee| David A. Liebelt | grad student | 2008 | Yeshiva University |
| Alexis Scherl | grad student | 2009 | Yeshiva University |
| Nicole K. McKinnon | grad student | 2010 | Yeshiva University |
| Paul M. Riegelhaupt | grad student | 2010 | Yeshiva University |
| Ithiel J. Frame | grad student | 2013 | Yeshiva University |
| Moez Bali | post-doc | Albert Einstein | |
| Michaela Jansen | post-doc | ||
| David C. Reeves | post-doc | Albert Einstein | |
| Amal Kanti Bera | post-doc | 2001-2004 | Albert Einstein |
BETA: Related publications
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Publications
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| Sosa Y, Deniskin R, Frame IJ, et al. (2019) Parallel Hit Progression Strategy Identifies Improved Small Molecule Inhibitors of the Malaria Purine Uptake Transporter that Inhibit Parasite Proliferation. Acs Infectious Diseases |
| Nishtala SN, Arora A, Reyes J, et al. (2018) Accessibility of substituted cysteines in TM2 and TM10 transmembrane segments in the equilibrative nucleoside transporter PfENT1. The Journal of Biological Chemistry |
| Arora A, Deniskin R, Sosa Y, et al. (2016) Substrate and inhibitor specificity of the Plasmodium berghei Equilibrative Nucleoside Transporter Type 1 (PbENT1). Molecular Pharmacology |
| Deniskin R, Frame IJ, Sosa Y, et al. (2016) Targeting the Plasmodium vivax equilibrative nucleoside transporter 1 (PvENT1) for antimalarial drug development. International Journal For Parasitology. Drugs and Drug Resistance. 6: 1-11 |
| Akabas MH. (2015) Cysteine Modification: Probing Channel Structure, Function and Conformational Change. Advances in Experimental Medicine and Biology. 869: 25-54 |
| Frame IJ, Deniskin R, Rinderspacher A, et al. (2015) Yeast-based high-throughput screen identifies Plasmodium falciparum equilibrative nucleoside transporter 1 inhibitors that kill malaria parasites. Acs Chemical Biology. 10: 775-83 |
| Frame IJ, Deniskin R, Arora A, et al. (2015) Purine import into malaria parasites as a target for antimalarial drug development. Annals of the New York Academy of Sciences. 1342: 19-28 |
| Akabas MH. (2013) Using molecular dynamics to elucidate the structural basis for function in pLGICs. Proceedings of the National Academy of Sciences of the United States of America. 110: 16700-1 |
| Brunner R, Ng CL, Aissaoui H, et al. (2013) UV-triggered affinity capture identifies interactions between the Plasmodium falciparum multidrug resistance protein 1 (PfMDR1) and antimalarial agents in live parasitized cells. The Journal of Biological Chemistry. 288: 22576-83 |
| Akabas MH. (2012) Channels: Rotamers affect ion conductance. Nature Chemical Biology. 8: 953-4 |