Ole Isacson
Affiliations: | Harvard Medical School, Boston, MA, United States |
Area:
NeuroregenerationGoogle:
"Ole Isacson"Mean distance: 15.2 (cluster 11)
Children
Sign in to add trainee| Ryan Richardson | research assistant | 2008-2009 | McLean Hospital - Harvard Medical School |
| Chee Yeun Chung | post-doc | Whitehead Institute | |
| Stephen B Tatter | post-doc | 1992-1997 | Harvard Medical School |
| Gaynor A Smith | post-doc | 2011-2014 |
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Publications
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| Brekk OR, Korecka JA, Crapart CC, et al. (2020) Upregulating β-hexosaminidase activity in rodents prevents α-synuclein lipid associations and protects dopaminergic neurons from α-synuclein-mediated neurotoxicity. Acta Neuropathologica Communications. 8: 127 |
| Thomas R, Hallett PJ, Isacson O. (2020) Experimental studies of mitochondrial and lysosomal function in in vitro and in vivo models relevant to Parkinson's disease genetic risk. International Review of Neurobiology. 154: 279-302 |
| Korecka JA, Thomas R, Hinrich AJ, et al. (2020) Splice-Switching Antisense Oligonucleotides Reduce LRRK2 Kinase Activity in Human LRRK2 Transgenic Mice. Molecular Therapy. Nucleic Acids. 21: 623-635 |
| Osborn TM, Hallett PJ, Schumacher JM, et al. (2020) Advantages and Recent Developments of Autologous Cell Therapy for Parkinson's Disease Patients. Frontiers in Cellular Neuroscience. 14: 58 |
| Huebecker M, Moloney EB, van der Spoel AC, et al. (2019) Reduced sphingolipid hydrolase activities, substrate accumulation and ganglioside decline in Parkinson's disease. Molecular Neurodegeneration. 14: 40 |
| Isacson O, Brekk OR, Hallett PJ. (2019) Novel Results and Concepts Emerging From Lipid Cell Biology Relevant to Degenerative Brain Aging and Disease. Frontiers in Neurology. 10: 1053 |
| Menon V, Thomas R, Elgueta C, et al. (2019) Comprehensive cell surface antigen analysis identifies transferrin receptor protein-1 (CD71) as a negative selection marker for human neuronal cells. Stem Cells (Dayton, Ohio) |
| Hallett PJ, Engelender S, Isacson O. (2019) Lipid and immune abnormalities causing age-dependent neurodegeneration and Parkinson's disease. Journal of Neuroinflammation. 16: 153 |
| Korecka JA, Thomas R, Christensen DP, et al. (2019) Mitochondrial clearance and maturation of autophagosomes are compromised in LRRK2 G2019S familial Parkinson's disease patient fibroblasts. Human Molecular Genetics |
| Korecka JA, Talbot S, Osborn TM, et al. (2019) Neurite Collapse and Altered ER Ca Control in Human Parkinson Disease Patient iPSC-Derived Neurons with LRRK2 G2019S Mutation. Stem Cell Reports. 12: 29-41 |